TreeWAS – Variant ID: rs7283054

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
# Top node	0.924	0.076	0.000
Chapter XXI Factors influencing health status and contact with health services	0.911	0.089	0.000
Chapter II Neoplasms	0.898	0.102	0.000
Z40-Z54 Persons encountering health services for specific procedures and health care	0.878	0.122	0.000
Chapter X Diseases of the respiratory system	0.877	0.123	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.846	0.154	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.833	0.166	0.000
D10-D36 Benign neoplasms	0.808	0.192	0.000
Z53 Persons encountering health services for specifie procedures, not carried out	0.806	0.194	0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.804	0.196	0.000
C50-C50 Malignant neoplasm of breast	0.800	0.200	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.799	0.201	0.000
J40-J47 Chronic lower respiratory diseases	0.782	0.218	0.000
Chapter VI Diseases of the nervous system	0.773	0.227	0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.768	0.232	0.000
Z51 Other medical care	0.767	0.233	0.000
Chapter VII Diseases of the eye and adnexa	0.765	0.235	0.000
J30-J39 Other diseases of upper respiratory tract	0.762	0.238	0.000
Z85 Personal history of malignant neoplasm	0.759	0.241	0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.754	0.246	0.000
M20-M25 Other joint disorders	0.748	0.252	0.000
E70-E90 Metabolic disorders	0.743	0.257	0.000
Chapter IX Diseases of the circulatory system	0.741	0.259	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.739	0.261	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.730	0.270	0.000
C50 Malignant neoplasm of breast	0.729	0.271	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.718	0.282	0.000
Z85.3 Personal history of malignant neoplasm of breast	0.717	0.283	0.000
Z46 Fitting and adjustment of other devices	0.713	0.287	0.000
J45 Asthma	0.709	0.290	0.000
Chapter XIV Diseases of the genitourinary system	0.707	0.293	0.000
Z88.0 Personal history of allergy to penicillin	0.701	0.299	0.000
Z53.8 Procedure not carried out for other reasons	0.696	0.304	0.000
E00-E07 Disorders of thyroid gland	0.694	0.306	0.000
J09-J18 Influenza and pneumonia	0.693	0.307	0.000
E10-E14 Diabetes mellitus	0.682	0.318	0.000
Chapter I Certain infectious and parasitic diseases	0.682	0.318	0.000
J95-J99 Other diseases of the respiratory system	0.673	0.327	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.673	0.327	0.000
Z37 Outcome of delivery	0.668	0.332	0.000
C60-C63 Malignant neoplasms of male genital organs	0.667	0.333	0.000
D24 Benign neoplasm of breast	0.665	0.335	0.000
Chapter XXII Codes for special purposes	0.662	0.338	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.662	0.338	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.662	0.338	0.000
Z51.2 Other chemotherapy	0.662	0.338	0.000
Z88.6 Personal history of allergy to analgesic agent	0.661	0.339	0.000
J45.9 Asthma, unspecified	0.658	0.342	0.000
Z85.4 Personal history of malignant neoplasm of genital organs	0.657	0.343	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.655	0.345	0.000
L80-L99 Other disorders of the skin and subcutaneous tissue	0.654	0.345	0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.653	0.347	0.000
Chapter VIII Diseases of the ear and mastoid process	0.652	0.348	0.000
Z53.0 Procedure not carried out because of contraindication	0.651	0.349	0.000
L60-L75 Disorders of skin appendages	0.650	0.350	0.000
M20 Acquired deformities of fingers and toes	0.649	0.351	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.648	0.352	0.000
Z53.9 Procedure not carried out, unspecified reason	0.648	0.352	0.000
C50.9 Breast, unspecified	0.645	0.355	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.644	0.356	0.000
D00-D09 In situ neoplasms	0.644	0.356	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.644	0.356	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.644	0.356	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.644	0.356	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.644	0.356	0.000
C64-C68 Malignant neoplasms of urinary tract	0.644	0.356	0.000
C51-C58 Malignant neoplasms of female genital organs	0.644	0.356	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.644	0.356	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.644	0.356	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.644	0.356	0.000
C15-C26 Malignant neoplasms of digestive organs	0.644	0.356	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.644	0.356	0.000
I30-I52 Other forms of heart disease	0.642	0.358	0.000
D18 Haemangioma and lymphangioma, any site	0.641	0.359	0.000
Chapter XX External causes of morbidity and mortality	0.640	0.360	0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.638	0.362	0.000
M80-M85 Disorders of bone density and structure	0.637	0.362	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.636	0.364	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.633	0.367	0.000
Z54 Convalescence	0.630	0.370	0.000
Z52 Donors of organs and tissues	0.630	0.370	0.000
Z50 Care involving use of rehabilitation procedures	0.630	0.370	0.000
Z49 Care involving dialysis	0.630	0.370	0.000
Z48 Other surgical follow-up care	0.630	0.370	0.000
Z45 Adjustment and management of implanted device	0.630	0.370	0.000
Z44 Fitting and adjustment of external prosthetic device	0.630	0.370	0.000
Z43 Attention to artificial openings	0.630	0.370	0.000
Z42 Follow-up care involving plastic surgery	0.630	0.370	0.000
Z41 Procedures for purposes other than remedying health state	0.630	0.370	0.000
Z40 Prophylactic surgery	0.630	0.370	0.000
J32 Chronic sinusitis	0.629	0.371	0.000
Z00-Z13 Persons encountering health services for examination and investigation	0.629	0.371	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.628	0.371	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.628	0.371	0.000
J60-J70 Lung diseases due to external agents	0.628	0.371	0.000
J00-J06 Acute upper respiratory infections	0.628	0.371	0.000
M15-M19 Arthrosis	0.627	0.373	0.000
J90-J94 Other diseases of pleura	0.626	0.374	0.000
M05-M14 Inflammatory polyarthropathies	0.626	0.374	0.000
D27 Benign neoplasm of ovary	0.620	0.380	0.000
M23 Internal derangement of knee	0.617	0.383	0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.610	0.389	0.000
Z47 Other orthopaedic follow-up care	0.610	0.390	0.000
E50-E64 Other nutritional deficiencies	0.606	0.393	0.000
E40-E46 Malnutrition	0.606	0.393	0.000
E20-E35 Disorders of other endocrine glands	0.606	0.393	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.606	0.393	0.000
C50.4 Upper-outer quadrant of breast	0.607	0.393	0.000
D17 Benign lipomatous neoplasm	0.606	0.394	0.000
E78.0 Pure hypercholesterolaemia	0.602	0.398	0.000
H25-H28 Disorders of lens	0.599	0.401	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.598	0.402	0.000
M91-M94 Chondropathies	0.598	0.402	0.000
M86-M90 Other osteopathies	0.598	0.402	0.000
M65-M68 Disorders of synovium and tendon	0.598	0.402	0.000
M60-M63 Disorders of muscles	0.598	0.402	0.000
M50-M54 Other dorsopathies	0.598	0.402	0.000
M45-M49 Spondylopathies	0.598	0.402	0.000
M40-M43 Deforming dorsopathies	0.598	0.402	0.000
M00-M03 Infectious arthropathies	0.598	0.402	0.000
Z37.0 Single live birth	0.596	0.404	0.000
J34 Other disorders of nose and nasal sinuses	0.596	0.404	0.000
D22 Melanocytic naevi	0.595	0.404	0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.595	0.405	0.000
Z46.6 Fitting and adjustment of urinary device	0.595	0.405	0.000
N30-N39 Other diseases of urinary system	0.595	0.405	0.000
Chapter V Mental and behavioural disorders	0.593	0.406	0.000
H30-H36 Disorders of choroid and retina	0.593	0.407	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.591	0.409	0.000
Z51.1 Chemotherapy session for neoplasm	0.590	0.410	0.000
J33 Nasal polyp	0.588	0.412	0.000
D25 Leiomyoma of uterus	0.586	0.414	0.000
E03 Other hypothyroidism	0.584	0.415	0.000
G40-G47 Episodic and paroxysmal disorders	0.584	0.416	0.000
Z92 Personal history of medical treatment	0.582	0.418	0.000
Z60 Problems related to social environment	0.581	0.419	0.000
D36 Benign neoplasm of other and unspecified sites	0.580	0.420	0.000
D35 Benign neoplasm of other and unspecified endocrine glands	0.580	0.420	0.000
D33 Benign neoplasm of brain and other parts of central nervous system	0.580	0.420	0.000
D32 Benign neoplasm of meninges	0.580	0.420	0.000
D31 Benign neoplasm of eye and adnexa	0.580	0.420	0.000
D30 Benign neoplasm of urinary organs	0.580	0.420	0.000
D29 Benign neoplasm of male genital organs	0.580	0.420	0.000
D28 Benign neoplasm of other and unspecified female genital organs	0.580	0.420	0.000
D26 Other benign neoplasms of uterus	0.580	0.420	0.000
D23 Other benign neoplasms of skin	0.580	0.420	0.000
D21 Other benign neoplasms of connective and other soft tissue	0.580	0.420	0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.580	0.420	0.000
D19 Benign neoplasm of mesothelial tissue	0.580	0.420	0.000
D16 Benign neoplasm of bone and articular cartilage	0.580	0.420	0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.580	0.420	0.000
D14 Benign neoplasm of middle ear and respiratory system	0.580	0.420	0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.580	0.420	0.000
D11 Benign neoplasm of major salivary glands	0.580	0.420	0.000
D10 Benign neoplasm of mouth and pharynx	0.580	0.420	0.000
D34 Benign neoplasm of thyroid gland	0.580	0.420	0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons	0.578	0.422	0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure	0.578	0.422	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.576	0.424	0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.576	0.424	0.000
Z97 Presence of other devices	0.576	0.424	0.000
Z94 Transplanted organ and tissue status	0.576	0.424	0.000
Z93 Artificial opening status	0.576	0.424	0.000
Z89 Acquired absence of limb	0.576	0.424	0.000
Z84 Family history of other conditions	0.576	0.424	0.000
Z83 Family history of other specific disorders	0.576	0.424	0.000
Z81 Family history of mental and behavioural disorders	0.576	0.424	0.000
J44 Other chronic obstructive pulmonary disease	0.574	0.426	0.000
Z98 Other postsurgical states	0.573	0.427	0.000
L50-L54 Urticaria and erythema	0.573	0.427	0.000
L40-L45 Papulosquamous disorders	0.573	0.427	0.000
L20-L30 Dermatitis and eczema	0.573	0.427	0.000
L10-L14 Bullous disorders	0.573	0.427	0.000
G56 Mononeuropathies of upper limb	0.572	0.428	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.572	0.428	0.000
O80-O84 Delivery	0.569	0.431	0.000
E86 Volume depletion	0.568	0.432	0.000
J20-J22 Other acute lower respiratory infections	0.566	0.433	0.000
I10-I15 Hypertensive diseases	0.566	0.434	0.000
J18 Pneumonia, organism unspecified	0.561	0.439	0.000
J43 Emphysema	0.560	0.439	0.000
J41 Simple and mucopurulent chronic bronchitis	0.560	0.439	0.000
J47 Bronchiectasis	0.560	0.439	0.000
J46 Status asthmaticus	0.560	0.439	0.000
J42 Unspecified chronic bronchitis	0.560	0.439	0.000
J40 Bronchitis, not specified as acute or chronic	0.560	0.439	0.000
H40-H42 Glaucoma	0.557	0.442	0.000
Z51.5 Palliative care	0.557	0.443	0.000
N20-N23 Urolithiasis	0.556	0.444	0.000
M70-M79 Other soft tissue disorders	0.555	0.445	0.000
Z51.0 Radiotherapy session	0.555	0.445	0.000
G90-G99 Other disorders of the nervous system	0.554	0.446	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.554	0.446	0.000
G70-G73 Diseases of myoneural junction and muscle	0.554	0.446	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.554	0.446	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.554	0.446	0.000
G30-G32 Other degenerative diseases of the nervous system	0.554	0.446	0.000
G20-G26 Extrapyramidal and movement disorders	0.554	0.446	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.554	0.446	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.554	0.446	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.552	0.448	0.000
L82 Seborrhoeic keratosis	0.552	0.448	0.000
Z39 Postpartum care and examination	0.551	0.449	0.000
Z38 Liveborn infants according to place of birth	0.551	0.449	0.000
Z36 Antenatal screening	0.551	0.449	0.000
Z35 Supervision of high-risk pregnancy	0.551	0.449	0.000
Z34 Supervision of normal pregnancy	0.551	0.449	0.000
Z32 Pregnancy examination and test	0.551	0.449	0.000
Z31 Procreative management	0.551	0.449	0.000
Z33 Pregnant state, incidental	0.551	0.449	0.000
Z51.9 Medical care, unspecified	0.550	0.450	0.000
Z51.8 Other specified medical care	0.550	0.450	0.000
Z51.6 Desensitisation to allergens	0.550	0.450	0.000
Z51.4 Preparatory care for treatment, not elsewhere classified	0.550	0.450	0.000
Z51.3 Blood transfusion without reported diagnosis	0.550	0.450	0.000
H55-H59 Other disorders of eye and adnexa	0.549	0.451	0.000
H53-H54 Visual disturbances and blindness	0.549	0.451	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.549	0.451	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.549	0.451	0.000
H43-H45 Disorders of vitreous body and globe	0.549	0.451	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.549	0.451	0.000
H10-H13 Disorders of conjunctiva	0.549	0.451	0.000
Z91 Personal history of risk-factors, not elsewhere classified	0.548	0.452	0.000
M20.1 Hallux valgus (acquired)	0.547	0.452	0.000
E65-E68 Obesity and other hyperalimentation	0.547	0.453	0.000
Z30 Contraceptive management	0.547	0.453	0.000
J39 Other diseases of upper respiratory tract	0.546	0.454	0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.546	0.454	0.000
J37 Chronic laryngitis and laryngotracheitis	0.546	0.454	0.000
J35 Chronic diseases of tonsils and adenoids	0.546	0.454	0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.546	0.454	0.000
J30 Vasomotor and allergic rhinitis	0.546	0.454	0.000
J36 Peritonsillar abscess	0.546	0.454	0.000
Z85.0 Personal history of malignant neoplasm of digestive organs	0.544	0.456	0.000
Z85.9 Personal history of malignant neoplasm, unspecified	0.544	0.456	0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues	0.544	0.456	0.000
Z85.6 Personal history of leukaemia	0.544	0.456	0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs	0.544	0.456	0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung	0.544	0.456	0.000
L72 Follicular cysts of skin and subcutaneous tissue	0.544	0.456	0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances	0.541	0.459	0.000
Z88.7 Personal history of allergy to serum and vaccine	0.541	0.459	0.000
Z88.5 Personal history of allergy to narcotic agent	0.541	0.459	0.000
Z88.4 Personal history of allergy to anaesthetic agent	0.541	0.459	0.000
Z88.3 Personal history of allergy to other anti-infective agents	0.541	0.459	0.000
Z88.2 Personal history of allergy to sulphonamides	0.541	0.459	0.000
Z88.1 Personal history of allergy to other antibiotic agents	0.541	0.459	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.536	0.464	0.000
M35 Other systemic involvement of connective tissue	0.536	0.464	0.000
M34 Systemic sclerosis	0.536	0.464	0.000
M33 Dermatopolymyositis	0.536	0.464	0.000
M32 Systemic lupus erythematosus	0.536	0.464	0.000
M31 Other necrotising vasculopathies	0.536	0.464	0.000
M30 Polyarteritis nodosa and related conditions	0.536	0.464	0.000
M24 Other specific joint derangements	0.536	0.464	0.000
M22 Disorders of patella	0.536	0.464	0.000
M21 Other acquired deformities of limbs	0.536	0.464	0.000
M25 Other joint disorders, not elsewhere classified	0.535	0.465	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.534	0.466	0.000
N10-N16 Renal tubulo-interstitial diseases	0.534	0.466	0.000
J32.9 Chronic sinusitis, unspecified	0.533	0.467	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.533	0.467	0.000
E88 Other metabolic disorders	0.533	0.467	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.533	0.467	0.000
E85 Amyloidosis	0.533	0.467	0.000
E84 Cystic fibrosis	0.533	0.467	0.000
E83 Disorders of mineral metabolism	0.533	0.467	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.533	0.467	0.000
E79 Disorders of purine and pyrimidine metabolism	0.533	0.467	0.000
E77 Disorders of glycoprotein metabolism	0.533	0.467	0.000
E76 Disorders of glycosaminoglycan metabolism	0.533	0.467	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.533	0.467	0.000
E74 Other disorders of carbohydrate metabolism	0.533	0.467	0.000
E73 Lactose intolerance	0.533	0.467	0.000
E72 Other disorders of amino-acid metabolism	0.533	0.467	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.533	0.467	0.000
E70 Disorders of aromatic amino-acid metabolism	0.533	0.467	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.533	0.467	0.000
E11 Non-insulin-dependent diabetes mellitus	0.532	0.468	0.000
E14 Unspecified diabetes mellitus	0.531	0.468	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.531	0.469	0.000
I05-I09 Chronic rheumatic heart diseases	0.531	0.469	0.000
I00-I02 Acute rheumatic fever	0.531	0.469	0.000
A30-A49 Other bacterial diseases	0.530	0.470	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.530	0.470	0.000
O85-O92 Complications predominantly related to the puerperium	0.530	0.470	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.530	0.470	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.530	0.470	0.000
O00-O08 Pregnancy with abortive outcome	0.530	0.470	0.000
O60-O75 Complications of labour and delivery	0.528	0.472	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.528	0.472	0.000
J98 Other respiratory disorders	0.527	0.473	0.000
C77.3 Axillary and upper limb lymph nodes	0.525	0.475	0.000
C80 Malignant neoplasm without specification of site	0.524	0.476	0.000
C76 Malignant neoplasm of other and ill-defined sites	0.524	0.476	0.000
M23.2 Derangement of meniscus due to old tear or injury	0.523	0.477	0.000
C50.8 Overlapping lesion of breast	0.523	0.477	0.000
C50.6 Axillary tail of breast	0.523	0.477	0.000
C50.5 Lower-outer quadrant of breast	0.523	0.477	0.000
C50.3 Lower-inner quadrant of breast	0.523	0.477	0.000
C50.2 Upper-inner quadrant of breast	0.523	0.477	0.000
C50.1 Central portion of breast	0.523	0.477	0.000
C50.0 Nipple and areola	0.523	0.477	0.000
I50 Heart failure	0.522	0.478	0.000
D18.0 Haemangioma, any site	0.521	0.479	0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.520	0.480	0.000
L57 Skin changes due to chronic exposure to nonionising radiation	0.519	0.481	0.000
C79 Secondary malignant neoplasm of other sites	0.519	0.481	0.000
G56.0 Carpal tunnel syndrome	0.518	0.482	0.000
I51 Complications and ill-defined descriptions of heart disease	0.518	0.482	0.000
I60-I69 Cerebrovascular diseases	0.518	0.482	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.515	0.485	0.000
Z65 Problems related to other psychosocial circumstances	0.515	0.485	0.000
Z64 Problems related to certain psychosocial circumstances	0.515	0.485	0.000
Z63 Other problems related to primary support group, including family circumstances	0.515	0.485	0.000
Z62 Other problems related to upbringing	0.515	0.485	0.000
Z61 Problems related to negative life events in childhood	0.515	0.485	0.000
Z59 Problems related to housing and economic circumstances	0.515	0.485	0.000
Z58 Problems related to physical environment	0.515	0.485	0.000
Z57 Occupational exposure to risk-factors	0.515	0.485	0.000
Z56 Problems related to employment and unemployment	0.515	0.485	0.000
Z55 Problems related to education and literacy	0.515	0.485	0.000
N17-N19 Renal failure	0.513	0.487	0.000
Z86 Personal history of certain other diseases	0.511	0.489	0.000
Z46.9 Fitting and adjustment of other unspecified device	0.511	0.489	0.000
Z46.8 Fitting and adjustment of other specified devices	0.511	0.489	0.000
Z46.7 Fitting and adjustment of orthopaedic device	0.511	0.489	0.000
Z46.5 Fitting and adjustment of ileostomy and other intestinal appliances	0.511	0.489	0.000
Z46.4 Fitting and adjustment of orthodontic device	0.511	0.489	0.000
Z46.3 Fitting and adjustment of dental prosthetic device	0.511	0.489	0.000
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses	0.511	0.489	0.000
Z46.1 Fitting and adjustment of hearing aid	0.511	0.489	0.000
Z46.0 Fitting and adjustment of spectacles and contact lenses	0.511	0.489	0.000
C44 Other malignant neoplasms of skin	0.511	0.489	0.000
J45.8 Mixed asthma	0.509	0.491	0.000
J45.1 Nonallergic asthma	0.509	0.491	0.000
J45.0 Predominantly allergic asthma	0.509	0.491	0.000
Z70-Z76 Persons encountering health services in other circumstances	0.507	0.492	0.001
Z80 Family history of malignant neoplasm	0.507	0.492	0.000
N32 Other disorders of bladder	0.507	0.493	0.000
N99-N99 Other disorders of the genitourinary system	0.507	0.493	0.000
N70-N77 Inflammatory diseases of female pelvic organs	0.507	0.493	0.000
N60-N64 Disorders of breast	0.507	0.493	0.000
N25-N29 Other disorders of kidney and ureter	0.507	0.493	0.000
N00-N08 Glomerular diseases	0.507	0.493	0.000
E03.9 Hypothyroidism, unspecified	0.506	0.494	0.000
Z87 Personal history of other diseases and conditions	0.504	0.495	0.000
Z85.5 Personal history of malignant neoplasm of urinary tract	0.503	0.497	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.502	0.497	0.000
C61 Malignant neoplasm of prostate	0.502	0.498	0.000
M20.5 Other deformities of toe(s) (acquired)	0.499	0.500	0.000
E07 Other disorders of thyroid	0.497	0.503	0.000
E06 Thyroiditis	0.497	0.503	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.497	0.503	0.000
E04 Other non-toxic goitre	0.497	0.503	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.497	0.503	0.000
E00 Congenital iodine-deficiency syndrome	0.497	0.503	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.497	0.503	0.000
M81 Osteoporosis without pathological fracture	0.497	0.503	0.000
J17 Pneumonia in diseases classified elsewhere	0.497	0.503	0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.497	0.503	0.000
J15 Bacterial pneumonia, not elsewhere classified	0.497	0.503	0.000
J12 Viral pneumonia, not elsewhere classified	0.497	0.503	0.000
J11 Influenza, virus not identified	0.497	0.503	0.000
J10 Influenza due to identified influenza virus	0.497	0.503	0.000
J14 Pneumonia due to Haemophilus influenzae	0.497	0.503	0.000
J13 Pneumonia due to Streptococcus pneumoniae	0.497	0.503	0.000
J09 Influenza due to certain identified influenza virus	0.497	0.503	0.000
M20.2 Hallux rigidus	0.494	0.506	0.000
E13 Other specified diabetes mellitus	0.489	0.511	0.000
E12 Malnutrition-related diabetes mellitus	0.489	0.511	0.000
E10 Insulin-dependent diabetes mellitus	0.489	0.511	0.000
B99-B99 Other infectious diseases	0.489	0.511	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.489	0.511	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.489	0.511	0.000
B65-B83 Helminthiases	0.489	0.511	0.000
B50-B64 Protozoal diseases	0.489	0.511	0.000
B35-B49 Mycoses	0.489	0.511	0.000
B25-B34 Other viral diseases	0.489	0.511	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.489	0.511	0.000
B15-B19 Viral hepatitis	0.489	0.511	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.489	0.511	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.489	0.511	0.000
A80-A89 Viral infections of the central nervous system	0.489	0.511	0.000
A75-A79 Rickettsioses	0.489	0.511	0.000
A70-A74 Other diseases caused by chlamydiae	0.489	0.511	0.000
A65-A69 Other spirochaetal diseases	0.489	0.511	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.489	0.511	0.000
A20-A28 Certain zoonotic bacterial diseases	0.489	0.511	0.000
A15-A19 Tuberculosis	0.489	0.511	0.000
M19 Other arthrosis	0.488	0.512	0.000
Z13 Special screening examination for other diseases and disorders	0.488	0.512	0.000
H26 Other cataract	0.486	0.514	0.000
I44 Atrioventricular and left bundle-branch block	0.484	0.516	0.000
I95 Hypotension	0.483	0.516	0.000
J34.8 Other specified disorders of nose and nasal sinuses	0.483	0.516	0.000
J99 Respiratory disorders in diseases classified elsewhere	0.483	0.517	0.000
J96 Respiratory failure, not elsewhere classified	0.483	0.517	0.000
J95 Postprocedural respiratory disorders, not elsewhere classified	0.483	0.517	0.000
B95-B98 Bacterial, viral and other infectious agents	0.482	0.517	0.000
C43 Malignant melanoma of skin	0.482	0.518	0.000
M06 Other rheumatoid arthritis	0.482	0.518	0.000
Z60.2 Living alone	0.482	0.518	0.000
Chapter XI Diseases of the digestive system	0.480	0.520	0.000
Z37.9 Outcome of delivery unspecified	0.479	0.521	0.000
Z37.7 Other multiple births, all stillborn	0.479	0.521	0.000
Z37.6 Other multiple births, some liveborn	0.479	0.521	0.000
Z37.5 Other multiple births, all liveborn	0.479	0.521	0.000
Z37.4 Twins, both stillborn	0.479	0.521	0.000
Z37.3 Twins, one liveborn and one stillborn	0.479	0.521	0.000
Z37.2 Twins, both liveborn	0.479	0.521	0.000
Z37.1 Single stillbirth	0.479	0.521	0.000
C63 Malignant neoplasm of other and unspecified male genital organs	0.478	0.521	0.000
C62 Malignant neoplasm of testis	0.478	0.521	0.000
C60 Malignant neoplasm of penis	0.478	0.521	0.000
P90-P96 Other disorders originating in the perinatal period	0.475	0.525	0.000
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn	0.475	0.525	0.000
P75-P78 Digestive system disorders of fetus and newborn	0.475	0.525	0.000
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn	0.475	0.525	0.000
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn	0.475	0.525	0.000
P35-P39 Infections specific to the perinatal period	0.475	0.525	0.000
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period	0.475	0.525	0.000
P10-P15 Birth trauma	0.475	0.525	0.000
P05-P08 Disorders related to length of gestation and fetal growth	0.475	0.525	0.000
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery	0.475	0.525	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.475	0.525	0.000
Q80-Q89 Other congenital malformations	0.475	0.525	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.475	0.525	0.000
Q60-Q64 Congenital malformations of the urinary system	0.475	0.525	0.000
Q50-Q56 Congenital malformations of genital organs	0.475	0.525	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.475	0.525	0.000
Q35-Q37 Cleft lip and cleft palate	0.475	0.525	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.475	0.525	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.475	0.525	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.475	0.525	0.000
Q00-Q07 Congenital malformations of the nervous system	0.475	0.525	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.475	0.525	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.475	0.525	0.000
D12.0 Caecum	0.475	0.525	0.000
M10 Gout	0.474	0.526	0.000
J18.9 Pneumonia, unspecified	0.474	0.526	0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.474	0.526	0.000
N35 Urethral stricture	0.471	0.528	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.470	0.530	0.000
E78.8 Other disorders of lipoprotein metabolism	0.470	0.530	0.000
E78.6 Lipoprotein deficiency	0.470	0.530	0.000
E78.4 Other hyperlipidaemia	0.470	0.530	0.000
E78.3 Hyperchylomicronaemia	0.470	0.530	0.000
E78.2 Mixed hyperlipidaemia	0.470	0.530	0.000
E78.1 Pure hyperglyceridaemia	0.470	0.530	0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems	0.469	0.530	0.000
H35 Other retinal disorders	0.469	0.531	0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.469	0.531	0.000
L95 Vasculitis limited to skin, not elsewhere classified	0.469	0.531	0.000
L94 Other localised connective tissue disorders	0.469	0.531	0.000
L93 Lupus erythematosus	0.469	0.531	0.000
L92 Granulomatous disorders of skin and subcutaneous tissue	0.469	0.531	0.000
L91 Hypertrophic disorders of skin	0.469	0.531	0.000
L90 Atrophic disorders of skin	0.469	0.531	0.000
L89 Decubitus ulcer	0.469	0.531	0.000
L87 Transepidermal elimination disorders	0.469	0.531	0.000
L85 Other epidermal thickening	0.469	0.531	0.000
L81 Other disorders of pigmentation	0.469	0.531	0.000
L97 Ulcer of lower limb, not elsewhere classified	0.469	0.531	0.000
L88 Pyoderma gangrenosum	0.469	0.531	0.000
L86 Keratoderma in diseases classified elsewhere	0.469	0.531	0.000
L84 Corns and callosities	0.469	0.531	0.000
L83 Acanthosis nigricans	0.469	0.531	0.000
L80 Vitiligo	0.469	0.531	0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.468	0.531	0.000
Z29 Need for other prophylactic measures	0.468	0.532	0.000
Z28 Immunisation not carried out	0.468	0.532	0.000
Z27 Need for immunisation against combinations of infectious diseases	0.468	0.532	0.000
Z26 Need for immunisation against other single infectious diseases	0.468	0.532	0.000
Z25 Need for immunisation against other single viral diseases	0.468	0.532	0.000
Z24 Need for immunisation against certain single viral diseases	0.468	0.532	0.000
Z23 Need for immunisation against single bacterial diseases	0.468	0.532	0.000
Z22 Carrier of infectious disease	0.468	0.532	0.000
Z20 Contact with and exposure to communicable diseases	0.468	0.532	0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status	0.468	0.532	0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.468	0.532	0.000
H80-H83 Diseases of inner ear	0.467	0.532	0.000
H65-H75 Diseases of middle ear and mastoid	0.467	0.532	0.000
H60-H62 Diseases of external ear	0.467	0.532	0.000
A00-A09 Intestinal infectious diseases	0.467	0.533	0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs	0.467	0.533	0.000
L75 Apocrine sweat disorders	0.466	0.534	0.000
L74 Eccrine sweat disorders	0.466	0.534	0.000
L73 Other follicular disorders	0.466	0.534	0.000
L71 Rosacea	0.466	0.534	0.000
L70 Acne	0.466	0.534	0.000
L68 Hypertrichosis	0.466	0.534	0.000
L67 Hair colour and hair shaft abnormalities	0.466	0.534	0.000
L66 Cicatricial alopecia [scarring hair loss]	0.466	0.534	0.000
L65 Other nonscarring hair loss	0.466	0.534	0.000
L64 Androgenic alopecia	0.466	0.534	0.000
L63 Alopecia areata	0.466	0.534	0.000
L62 Nail disorders in diseases classified elsewhere	0.466	0.534	0.000
L60 Nail disorders	0.466	0.534	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.466	0.534	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations