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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72845730
log Bayes Factor = 263.988
Chromosome 6   position 32,526,731  (GRCh37) Explore rs72845730 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
K51 Ulcerative colitis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E14.9 Without complications
0.000 0.000 1.000
Z93.2 Ileostomy status
1.000 0.000 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
C44.3 Skin of other and unspecified parts of face
1.000 0.000 0.000
J40-J47 Chronic lower respiratory diseases
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
J45 Asthma
0.000 0.000 1.000
Chapter X Diseases of the respiratory system
0.000 0.000 1.000
H36 Retinal disorders in diseases classified elsewhere
0.000 0.001 0.999
E10.4 With neurological complications
0.000 0.001 0.999
K90 Intestinal malabsorption
0.000 0.001 0.999
K51.4 Pseudopolyposis of colon
0.999 0.001 0.000
H30-H36 Disorders of choroid and retina
0.000 0.001 0.999
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
Chapter XI Diseases of the digestive system
0.000 0.001 0.999
C44 Other malignant neoplasms of skin
0.998 0.002 0.000
K90-K93 Other diseases of the digestive system
0.000 0.002 0.998
Chapter VII Diseases of the eye and adnexa
0.000 0.003 0.997
K51.8 Other ulcerative colitis
0.996 0.004 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.995 0.005 0.000
K70-K77 Diseases of liver
0.000 0.005 0.995
E14.3 With ophthalmic complications
0.000 0.008 0.992
H43-H45 Disorders of vitreous body and globe
0.000 0.008 0.992
H43 Disorders of vitreous body
0.000 0.010 0.990
G35-G37 Demyelinating diseases of the central nervous system
0.987 0.012 0.001
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.013 0.987
J33 Nasal polyp
0.000 0.013 0.987
E05.9 Thyrotoxicosis, unspecified
0.000 0.013 0.987
E11.1 With ketoacidosis
0.000 0.014 0.986
J33.9 Nasal polyp, unspecified
0.000 0.014 0.986
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.014 0.986
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.015 0.985
G37 Other demyelinating diseases of central nervous system
0.984 0.015 0.000
E10.5 With peripheral circulatory complications
0.000 0.016 0.984
K51.2 Ulcerative (chronic) proctitis
0.984 0.016 0.000
K86 Other diseases of pancreas
0.000 0.017 0.983
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.018 0.982
E11.3 With ophthalmic complications
0.000 0.018 0.982
L90.0 Lichen sclerosus et atrophicus
0.000 0.018 0.982
L90 Atrophic disorders of skin
0.000 0.019 0.981
G37.9 Demyelinating disease of central nervous system, unspecified
0.981 0.019 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.019 0.981
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.020 0.980
J43 Emphysema
0.000 0.023 0.977
K75 Other inflammatory liver diseases
0.000 0.025 0.975
J33.8 Other polyp of sinus
0.000 0.028 0.972
L92 Granulomatous disorders of skin and subcutaneous tissue
0.000 0.029 0.971
L40-L45 Papulosquamous disorders
0.000 0.029 0.971
K75.4 Autoimmune hepatitis
0.000 0.029 0.971
D64.9 Anaemia, unspecified
0.000 0.029 0.971
D60-D64 Aplastic and other anaemias
0.000 0.030 0.970
D64 Other anaemias
0.000 0.031 0.969
H43.3 Other vitreous opacities
0.000 0.032 0.968
K86.1 Other chronic pancreatitis
0.000 0.033 0.967
L40 Psoriasis
0.000 0.036 0.964
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.036 0.964
J33.0 Polyp of nasal cavity
0.000 0.037 0.963
H34 Retinal vascular occlusions
0.000 0.039 0.961
J95-J99 Other diseases of the respiratory system
0.000 0.040 0.960
J43.9 Emphysema, unspecified
0.000 0.040 0.960
K74 Fibrosis and cirrhosis of liver
0.000 0.042 0.958
E10.8 With unspecified complications
0.000 0.043 0.957
L40.9 Psoriasis, unspecified
0.000 0.043 0.957
L80 Vitiligo
0.000 0.051 0.949
H43.8 Other disorders of vitreous body
0.000 0.051 0.949
E20-E35 Disorders of other endocrine glands
0.000 0.052 0.948
K86.0 Alcohol-induced chronic pancreatitis
0.000 0.054 0.946
L92.0 Granuloma annulare
0.000 0.058 0.942
E11.2 With renal complications
0.000 0.060 0.940
E11.5 With peripheral circulatory complications
0.000 0.060 0.940
C44.9 Malignant neoplasm of skin, unspecified
0.940 0.060 0.000
Chapter VIII Diseases of the ear and mastoid process
0.000 0.061 0.939
C44.7 Skin of lower limb, including hip
0.939 0.061 0.000
D50-D53 Nutritional anaemias
0.000 0.063 0.937
H60-H62 Diseases of external ear
0.000 0.064 0.936
J46 Status asthmaticus
0.000 0.065 0.935
J98 Other respiratory disorders
0.000 0.065 0.935
J86 Pyothorax
0.000 0.065 0.935
K90.9 Intestinal malabsorption, unspecified
0.000 0.067 0.933
E10.0 With coma
0.000 0.068 0.932
H61 Other disorders of external ear
0.000 0.071 0.929
H34.8 Other retinal vascular occlusions
0.000 0.075 0.925
C44.5 Skin of trunk
0.924 0.076 0.000
C44.1 Skin of eyelid, including canthus
0.924 0.076 0.000
D50 Iron deficiency anaemia
0.000 0.077 0.923
H61.0 Perichondritis of external ear
0.000 0.078 0.922
J30-J39 Other diseases of upper respiratory tract
0.000 0.079 0.921
D50.9 Iron deficiency anaemia, unspecified
0.000 0.079 0.921
Chapter IX Diseases of the circulatory system
0.000 0.080 0.920
K86.3 Pseudocyst of pancreas
0.000 0.081 0.919
I10-I15 Hypertensive diseases
0.000 0.084 0.916
K51.5 Mucosal proctocolitis
0.908 0.092 0.000
E11.6 With other specified complications
0.000 0.093 0.907
E24 Cushing's syndrome
0.000 0.094 0.906
E10.2 With renal complications
0.000 0.096 0.904
E03.8 Other specified hypothyroidism
0.000 0.096 0.904
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.097 0.903
K72 Hepatic failure, not elsewhere classified
0.000 0.097 0.903
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.000 0.103 0.897
I10 Essential (primary) hypertension
0.000 0.104 0.896
E13 Other specified diabetes mellitus
0.000 0.107 0.893
D80-D89 Certain disorders involving the immune mechanism
0.000 0.109 0.891
E83 Disorders of mineral metabolism
0.887 0.113 0.000
H43.1 Vitreous haemorrhage
0.000 0.113 0.887
H35 Other retinal disorders
0.000 0.117 0.883
J44 Other chronic obstructive pulmonary disease
0.000 0.117 0.883
J98.0 Diseases of bronchus, not elsewhere classified
0.000 0.117 0.883
E06 Thyroiditis
0.000 0.122 0.878
K74.3 Primary biliary cirrhosis
0.000 0.128 0.872
E83.3 Disorders of phosphorus metabolism
0.871 0.129 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.135 0.865
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.136 0.864
D86 Sarcoidosis
0.000 0.136 0.864
J86.9 Pyothorax without fistula
0.000 0.139 0.861
J98.4 Other disorders of lung
0.000 0.139 0.861
E10.6 With other specified complications
0.000 0.139 0.861
J86.0 Pyothorax with fistula
0.000 0.141 0.859
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.143 0.857
E14.8 With unspecified complications
0.000 0.145 0.855
E65-E68 Obesity and other hyperalimentation
0.000 0.146 0.854
K82 Other diseases of gallbladder
0.000 0.151 0.849
E27 Other disorders of adrenal gland
0.000 0.152 0.848
E16.1 Other hypoglycaemia
0.000 0.158 0.842
K73 Chronic hepatitis, not elsewhere classified
0.000 0.159 0.841
E07 Other disorders of thyroid
0.000 0.167 0.833
K86.8 Other specified diseases of pancreas
0.000 0.168 0.832
H60 Otitis externa
0.000 0.168 0.832
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.000 0.169 0.831
K74.6 Other and unspecified cirrhosis of liver
0.000 0.172 0.828
K74.5 Biliary cirrhosis, unspecified
0.000 0.172 0.828
K72.0 Acute and subacute hepatic failure
0.000 0.174 0.826
D86.9 Sarcoidosis, unspecified
0.000 0.175 0.825
I15 Secondary hypertension
0.000 0.176 0.824
I20-I25 Ischaemic heart diseases
0.000 0.176 0.824
E13.9 Without complications
0.000 0.180 0.820
L40.0 Psoriasis vulgaris
0.000 0.184 0.816
I24 Other acute ischaemic heart diseases
0.000 0.187 0.813
H35.2 Other proliferative retinopathy
0.000 0.189 0.811
K86.2 Cyst of pancreas
0.000 0.195 0.805
L10-L14 Bullous disorders
0.000 0.198 0.802
E14.6 With other specified complications
0.000 0.198 0.802
E27.1 Primary adrenocortical insufficiency
0.000 0.200 0.800
E06.3 Autoimmune thyroiditis
0.000 0.201 0.799
H53-H54 Visual disturbances and blindness
0.000 0.203 0.797
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.797 0.203 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.205 0.795
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.206 0.794
E40-E46 Malnutrition
0.000 0.208 0.792
E21.0 Primary hyperparathyroidism
0.000 0.209 0.791
E24.9 Cushing's syndrome, unspecified
0.000 0.212 0.788
E24.2 Drug-induced Cushing's syndrome
0.000 0.212 0.788
Q60-Q64 Congenital malformations of the urinary system
0.000 0.213 0.787
L40.8 Other psoriasis
0.000 0.213 0.787
J98.6 Disorders of diaphragm
0.000 0.215 0.785
K82.8 Other specified diseases of gallbladder
0.000 0.217 0.783
J98.9 Respiratory disorder, unspecified
0.000 0.219 0.781
Q80-Q89 Other congenital malformations
0.000 0.224 0.776
E66 Obesity
0.000 0.228 0.772
H61.8 Other specified disorders of external ear
0.000 0.228 0.772
H60.9 Otitis externa, unspecified
0.000 0.230 0.770
J43.2 Centrilobular emphysema
0.000 0.232 0.768
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.000 0.233 0.767
H61.3 Acquired stenosis of external ear canal
0.000 0.235 0.765
J42 Unspecified chronic bronchitis
0.000 0.235 0.765
E24.0 Pituitary-dependent Cushing's disease
0.000 0.236 0.764
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.237 0.763
C44.0 Skin of lip
0.760 0.240 0.000
E14.2 Withrenal complications
0.000 0.240 0.760
K74.0 Hepatic fibrosis
0.000 0.240 0.760
L40.1 Generalised pustular psoriasis
0.000 0.240 0.760
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.240 0.760
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.241 0.759
E14.5 With peripheral circulatory complications
0.000 0.241 0.759
D86.8 Sarcoidosis of other and combined sites
0.000 0.242 0.758
E14.4 With neurological complications
0.000 0.243 0.757
I12 Hypertensive renal disease
0.000 0.246 0.754
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.246 0.754
I85 Oesophageal varices
0.000 0.247 0.753
C44.4 Skin of scalp and neck
0.753 0.247 0.000
H34.2 Other retinal artery occlusions
0.000 0.249 0.751
E66.9 Obesity, unspecified
0.000 0.251 0.749
Q61 Cystic kidney disease
0.000 0.252 0.748
H35.8 Other specified retinal disorders
0.000 0.252 0.748
H35.0 Background retinopathy and retinal vascular changes
0.000 0.252 0.748
I11 Hypertensive heart disease
0.000 0.253 0.747
H43.2 Crystalline deposits in vitreous body
0.000 0.257 0.743
E21.3 Hyperparathyroidism, unspecified
0.000 0.257 0.743
C44.2 Skin of ear and external auricular canal
0.742 0.258 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.258 0.742
K51.0 Ulcerative (chronic) enterocolitis
0.741 0.259 0.000
L94 Other localised connective tissue disorders
0.000 0.260 0.740
H54 Blindness and low vision
0.000 0.261 0.739
I86 Varicose veins of other sites
0.000 0.261 0.739
C44.6 Skin of upper limb, including shoulder
0.737 0.263 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.736 0.264 0.000
I85.9 Oesophageal varices without bleeding
0.000 0.264 0.736
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.264 0.736
J33.1 Polypoid sinus degeneration
0.000 0.266 0.734
J98.8 Other specified respiratory disorders
0.000 0.266 0.734
J85 Abscess of lung and mediastinum
0.000 0.276 0.724
G36 Other acute disseminated demyelination
0.721 0.278 0.001
H35.6 Retinal haemorrhage
0.000 0.279 0.721
H34.9 Retinal vascular occlusion, unspecified
0.000 0.280 0.720
E07.9 Disorder of thyroid, unspecified
0.000 0.280 0.720
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
Q85 Phakomatoses, not elsewhere classified
0.000 0.283 0.717
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.283 0.716
K90.3 Pancreatic steatorrhoea
0.000 0.284 0.716
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.284 0.716
K90.1 Tropical sprue
0.000 0.284 0.716
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.284 0.716
E05.5 Thyroid crisis or storm
0.000 0.284 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.284 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.284 0.716
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.284 0.716
C44.8 Overlapping lesion of skin
0.716 0.284 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.285 0.715
N00-N08 Glomerular diseases
0.000 0.286 0.714
H54.7 Unspecified visual loss
0.000 0.286 0.714
J45.1 Nonallergic asthma
0.000 0.286 0.714
K77 Liver disorders in diseases classified elsewhere
0.000 0.287 0.713
J45.0 Predominantly allergic asthma
0.000 0.287 0.713
E83.9 Disorder of mineral metabolism, unspecified
0.712 0.288 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.288 0.712
Chapter XIV Diseases of the genitourinary system
0.000 0.289 0.711
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.289 0.711
H43.0 Vitreous prolapse
0.000 0.290 0.710
I86.4 Gastric varices
0.000 0.291 0.709
K82.9 Disease of gallbladder, unspecified
0.000 0.291 0.709
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.000 0.293 0.707
L87 Transepidermal elimination disorders
0.000 0.293 0.707
L86 Keratoderma in diseases classified elsewhere
0.000 0.293 0.707
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.293 0.707
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.293 0.707
H61.1 Non-infective disorders of pinna
0.000 0.294 0.706
G37.5 Concentric sclerosis [Balo]
0.706 0.294 0.000
G37.4 Subacute necrotising myelitis
0.706 0.294 0.000
G37.2 Central pontine myelinolysis
0.706 0.294 0.000
G37.1 Central demyelination of corpus callosum
0.706 0.294 0.000
G37.0 Diffuse sclerosis
0.706 0.294 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.000 0.296 0.704
L90.9 Atrophic disorder of skin, unspecified
0.000 0.296 0.704
L90.6 Striae atrophicae
0.000 0.296 0.704
L90.4 Acrodermatitis chronica atrophicans
0.000 0.296 0.704
L90.3 Atrophoderma of Pasini and Pierini
0.000 0.296 0.704
L90.2 Anetoderma of Jadassohn-Pellizzari
0.000 0.296 0.704
L90.1 Anetoderma of Schweninger-Buzzi
0.000 0.296 0.704
E29 Testicular dysfunction
0.000 0.296 0.704
N08 Glomerular disorders in diseases classified elsewhere
0.000 0.297 0.703
N05 Unspecified nephritic syndrome
0.000 0.298 0.702
N08.3 Glomerular disorders in diabetes mellitus
0.000 0.298 0.702
K71 Toxic liver disease
0.000 0.298 0.702
J37 Chronic laryngitis and laryngotracheitis
0.000 0.298 0.701
J98.2 Interstitial emphysema
0.000 0.299 0.701
J43.1 Panlobular emphysema
0.000 0.299 0.701
J43.0 MacLeod's syndrome
0.000 0.299 0.701
I15.9 Seconday hypertension, unspecified
0.000 0.299 0.701
L43 Lichen planus
0.000 0.300 0.700
K75.2 Nonspecific reactive hepatitis
0.000 0.301 0.699
K75.1 Phlebitis of portal vein
0.000 0.301 0.699
L92.2 Granuloma faciale [eosinophilic granuloma of skin]
0.000 0.304 0.696
L92.1 Necrobiosis lipoidica, not elsewhere classified
0.000 0.304 0.696
L44 Other papulosquamous disorders
0.000 0.304 0.696
L41 Parapsoriasis
0.000 0.304 0.696
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.304 0.696
Q61.2 Polycystic kidney, adult type
0.000 0.305 0.695
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.305 0.695
D86.1 Sarcoidosis of lymph nodes
0.000 0.305 0.695
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.305 0.695
D64.4 Congenital dyserythropoietic anaemia
0.000 0.305 0.694
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.305 0.694
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.305 0.694
D64.0 Hereditary sideroblastic anaemia
0.000 0.305 0.694
L13 Other bullous disorders
0.000 0.307 0.693
H30 Chorioretinal inflammation
0.000 0.307 0.693
L40.4 Guttate psoriasis
0.000 0.308 0.691
L40.3 Pustulosis palmaris et plantaris
0.000 0.308 0.691
L40.2 Acrodermatitis continua
0.000 0.308 0.691
Q89 Other congenital malformations, not elsewhere classified
0.000 0.308 0.691
J95.0 Tracheostomy malfunction
0.000 0.310 0.690
K72.9 Hepatic failure, unspecified
0.000 0.310 0.690
H34.0 Transient retinal artery occlusion
0.000 0.311 0.689
J96 Respiratory failure, not elsewhere classified
0.000 0.312 0.688
K74.4 Secondary biliary cirrhosis
0.000 0.313 0.687
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.313 0.687
Q61.3 Polycystic kidney, unspecified
0.000 0.314 0.686
I70 Atherosclerosis
0.000 0.316 0.684
D53 Other nutritional anaemias
0.000 0.317 0.683
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.320 0.680
J45.8 Mixed asthma
0.000 0.320 0.680
I86.8 Varicose veins of other specified sites
0.000 0.320 0.680
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.320 0.680
E32 Diseases of thymus
0.000 0.320 0.680
E31 Polyglandular dysfunction
0.000 0.320 0.680
E30 Disorders of puberty, not elsewhere classified
0.000 0.320 0.680
H35.4 Peripheral retinal degeneration
0.000 0.321 0.679
I15.1 Hypertension secondary to other renal disorders
0.000 0.322 0.678
J41 Simple and mucopurulent chronic bronchitis
0.000 0.324 0.676
H60.3 Other infective otitis externa
0.000 0.325 0.675
N40-N51 Diseases of male genital organs
0.000 0.328 0.672
H62 Disorders of external ear in diseases classified elsewhere
0.000 0.329 0.671
J98.3 Compensatory emphysema
0.000 0.330 0.670
N17-N19 Renal failure
0.000 0.330 0.670
N18 Chronic renal failure
0.000 0.331 0.669
E05.8 Other thyrotoxicosis
0.000 0.332 0.668
E20 Hypoparathyroidism
0.000 0.332 0.667
D83 Common variable immunodeficiency
0.000 0.334 0.665
N48 Other disorders of penis
0.000 0.335 0.665
D80 Immunodeficiency with predominantly antibody defects
0.000 0.335 0.665
N18.9 Chronic renal failure, unspecified
0.000 0.335 0.665
I85.0 Oesophageal varices with bleeding
0.000 0.336 0.664
H34.1 Central retinal artery occlusion
0.000 0.337 0.663
D50.1 Sideropenic dysphagia
0.000 0.338 0.662
I12.9 Hypertensive renal disease without renal failure
0.000 0.340 0.660
D55-D59 Haemolytic anaemias
0.000 0.342 0.658
K82.3 Fistula of gallbladder
0.000 0.344 0.656
E03.1 Congenital hypothyroidism without goitre
0.000 0.346 0.654
N47 Redundant prepuce, phimosis and paraphimosis
0.000 0.346 0.654
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.000 0.346 0.654
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.347 0.653
I00-I02 Acute rheumatic fever
0.000 0.349 0.651
H35.5 Hereditary retinal dystrophy
0.000 0.350 0.650
E24.8 Other Cushing's syndrome
0.000 0.350 0.650
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.350 0.650
E24.3 Ectopic ACTH syndrome
0.000 0.350 0.650
E24.1 Nelson's syndrome
0.000 0.350 0.650
Q85.9 Phakomatosis, unspecified
0.000 0.351 0.649
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.354 0.646
E11.8 With unspecified complications
0.000 0.354 0.646
H43.9 Disorder of vitreous body, unspecified
0.000 0.355 0.644
E46 Unspecified protein-energy malnutrition
0.000 0.357 0.643
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.357 0.643
I70.0 Atherosclerosis of aorta
0.000 0.357 0.643
J43.8 Other emphysema
0.000 0.358 0.642
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.000 0.358 0.642
H80-H83 Diseases of inner ear
0.000 0.359 0.641
K72.1 Chronic hepatic failure
0.000 0.359 0.641
E13.8 With unspecified complications
0.000 0.360 0.640
E13.7 With multiple complications
0.000 0.360 0.640
E13.6 With other specified complications
0.000 0.360 0.640
E13.5 With peripheral circulatory complications
0.000 0.360 0.640
E13.4 With neurological complications
0.000 0.360 0.640
E13.2 With renal complications
0.000 0.360 0.640
E13.1 With ketoacidosis
0.000 0.360 0.640
E13.0 With coma
0.000 0.360 0.640
D82 Immunodeficiency associated with other major defects
0.000 0.361 0.639
D81 Combined immunodeficiencies
0.000 0.361 0.639
K73.9 Chronic hepatitis, unspecified
0.000 0.362 0.638
Q60 Renal agenesis and other reduction defects of kidney
0.000 0.363 0.637
N04 Nephrotic syndrome
0.000 0.363 0.637
E83.8 Other disorders of mineral metabolism
0.636 0.364 0.000
E83.2 Disorders of zinc metabolism
0.636 0.364 0.000
E83.0 Disorders of copper metabolism
0.636 0.364 0.000
L84 Corns and callosities
0.000 0.364 0.636
K90.8 Other intestinal malabsorption
0.000 0.366 0.634
H35.1 Retinopathy of prematurity
0.000 0.367 0.633
N48.6 Balanitis xerotica obliterans
0.000 0.367 0.633
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.369 0.631
N05.2 Diffuse membranous glomerulonephritis
0.000 0.369 0.631
Q89.2 Congenital malformations of other endocrine glands
0.000 0.369 0.631
K51.1 Ulcerative (chronic) ileocolitis
0.630 0.369 0.000
E06.5 Other chronic thyroiditis
0.000 0.371 0.629
E06.4 Drug-induced thyroiditis
0.000 0.371 0.629
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.371 0.629
E06.1 Subacute thyroiditis
0.000 0.371 0.629
E06.0 Acute thyroiditis
0.000 0.371 0.629
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.000 0.371 0.629
J85.2 Abscess of lung without pneumonia
0.000 0.374 0.626
K75.8 Other specified inflammatory liver diseases
0.000 0.374 0.626
K82.2 Perforation of gallbladder
0.000 0.375 0.625
N48.0 Leukoplakia of penis
0.000 0.375 0.625
I15.0 Renovascular hypertension
0.000 0.375 0.625
E13.3 With ophthalmic complications
0.000 0.375 0.624
H60.8 Other otitis externa
0.000 0.378 0.622
N42 Other disorders of prostate
0.000 0.378 0.622
D86.3 Sarcoidosis of skin
0.000 0.381 0.619
Q83 Congenital malformations of breast
0.000 0.381 0.619
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.618 0.382 0.000
H54.0 Blindness, both eyes
0.000 0.383 0.617
E28 Ovarian dysfunction
0.000 0.384 0.616
L13.0 Dermatitis herpetiformis
0.000 0.385 0.615
N48.1 Balanoposthitis
0.000 0.386 0.614
I13 Hypertensive heart and renal disease
0.000 0.386 0.614
E11.0 With coma
0.000 0.386 0.614
D50.8 Other iron deficiency anaemias
0.000 0.386 0.614
D64.3 Other sideroblastic anaemias
0.000 0.386 0.613
H60.5 Acute otitis externa, non-infective
0.000 0.387 0.613
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.387 0.613
E67 Other hyperalimentation
0.000 0.387 0.612
E68 Sequelae of hyperalimentation
0.000 0.387 0.612
Q61.0 Congenital single renal cyst
0.000 0.389 0.611
K82.0 Obstruction of gallbladder
0.000 0.390 0.610
L90.8 Other atrophic disorders of skin
0.000 0.390 0.610
E27.5 Adrenomedullary hyperfunction
0.000 0.392 0.608
E27.0 Other adrenocortical overactivity
0.000 0.392 0.608
Q38-Q45 Other congenital malformations of the digestive system
0.000 0.393 0.607
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.606 0.394 0.000
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.397 0.603
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.397 0.603
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.397 0.603
E21.2 Other hyperparathyroidism
0.000 0.397 0.603
K75.9 Inflammatory liver disease, unspecified
0.000 0.397 0.603
I86.2 Pelvic varices
0.000 0.398 0.602
E06.9 Thyroiditis, unspecified
0.000 0.398 0.602
E21.4 Other specified disorders of parathyroid gland
0.000 0.400 0.599
N05.9 Unspecified
0.000 0.401 0.599
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.402 0.598
E07.1 Dyshormogenetic goitre
0.000 0.402 0.597
E07.0 Hypersecretion of calcitonin
0.000 0.402 0.597
H60.2 Malignant otitis externa
0.000 0.404 0.596
I74 Arterial embolism and thrombosis
0.000 0.406 0.594
N05.1 Focal and segmental glomerular lesions
0.000 0.406 0.594
Q85.0 Neurofibromatosis (nonmalignant)
0.000 0.407 0.593
H61.9 Disorder of external ear, unspecified
0.000 0.407 0.592
I15.8 Other secondary hypertension
0.000 0.409 0.591
I15.2 Hypertension secondary to endocrine disorders
0.000 0.409 0.591
I22 Subsequent myocardial infarction
0.000 0.410 0.590
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.000 0.413 0.587
E25 Adrenogenital disorders
0.000 0.413 0.586
I20 Angina pectoris
0.000 0.414 0.586
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.414 0.586
J95.9 Postprocedural respiratory disorder, unspecified
0.000 0.414 0.586
L11 Other acantholytic disorders
0.000 0.414 0.586
E07.8 Other specified disorders of thyroid
0.000 0.415 0.585
E26 Hyperaldosteronism
0.000 0.416 0.584
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.416 0.584
N04.9 Unspecified
0.000 0.419 0.581
N18.2 Chronic kidney disease, stage 2
0.000 0.419 0.581
H54.2 Low vision, both eyes
0.000 0.421 0.579
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.422 0.578
N05.8 Other
0.000 0.423 0.577
L10 Pemphigus
0.000 0.425 0.575
L14 Bullous disorders in diseases classified elsewhere
0.000 0.425 0.575
L94.2 Calcinosis cutis
0.000 0.425 0.575
E27.8 Other specified disorders of adrenal gland
0.000 0.426 0.574
L94.9 Localised connective tissue disorder, unspecified
0.000 0.426 0.573
I81 Portal vein thrombosis
0.000 0.427 0.573
E83.5 Disorders of calcium metabolism
0.571 0.429 0.000
Q35-Q37 Cleft lip and cleft palate
0.000 0.432 0.568
N42.9 Disorder of prostate, unspecified
0.000 0.432 0.568
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.432 0.568
E45 Retarded development following protein-energy malnutrition
0.000 0.432 0.568
E43 Unspecified severe protein-energy malnutrition
0.000 0.432 0.568
E42 Marasmic kwashiorkor
0.000 0.432 0.568
E41 Nutritional marasmus
0.000 0.432 0.568
E40 Kwashiorkor
0.000 0.432 0.568
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.434 0.566
L95 Vasculitis limited to skin, not elsewhere classified
0.000 0.436 0.564
Q00-Q07 Congenital malformations of the nervous system
0.000 0.436 0.563
I24.1 Dressler's syndrome
0.000 0.439 0.561
H54.1 Blindness, one eye, low vision, other eye
0.000 0.440 0.560
I23 Certain current complications following acute myocardial infarction
0.000 0.440 0.560
I72 Other aneurysm
0.000 0.441 0.559
E27.9 Disorder of adrenal gland, unspecified
0.000 0.442 0.558
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified
0.000 0.443 0.557
Q84 Other congenital malformations of integument
0.000 0.443 0.557
Q81 Epidermolysis bullosa
0.000 0.443 0.557
Q80 Congenital ichthyosis
0.000 0.443 0.557
Q30-Q34 Congenital malformations of the respiratory system
0.000 0.445 0.555
E66.1 Drug-induced obesity
0.000 0.446 0.554
N42.2 Atrophy of prostate
0.000 0.448 0.552
H60.4 Cholesteatoma of external ear
0.000 0.448 0.552

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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