TreeWAS – Variant ID: rs72849247

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	1.000	0.000	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	1.000	0.000	0.000
C44.3 Skin of other and unspecified parts of face	1.000	0.000	0.000
J45.9 Asthma, unspecified	0.000	0.000	1.000
K51.9 Ulcerative colitis, unspecified	1.000	0.000	0.000
K90.0 Coeliac disease	0.000	0.000	1.000
M06.9 Rheumatoid arthritis, unspecified	1.000	0.000	0.000
C44 Other malignant neoplasms of skin	1.000	0.000	0.000
K51 Ulcerative colitis	1.000	0.000	0.000
M06 Other rheumatoid arthritis	1.000	0.000	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.000	1.000
E10 Insulin-dependent diabetes mellitus	0.000	0.000	1.000
E10-E14 Diabetes mellitus	0.000	0.000	1.000
E10.9 Without complications	0.000	0.000	1.000
M05-M14 Inflammatory polyarthropathies	0.999	0.001	0.000
Z93.2 Ileostomy status	0.999	0.001	0.000
M06.0 Seronegative rheumatoid arthritis	0.999	0.001	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.999	0.001	0.000
E00-E07 Disorders of thyroid gland	0.000	0.001	0.999
C44.2 Skin of ear and external auricular canal	0.998	0.002	0.000
K50-K52 Noninfective enteritis and colitis	0.997	0.003	0.000
C44.7 Skin of lower limb, including hip	0.997	0.003	0.000
E03 Other hypothyroidism	0.000	0.003	0.997
E03.9 Hypothyroidism, unspecified	0.000	0.004	0.996
K50 Crohn's disease [regional enteritis]	0.996	0.004	0.000
K51.4 Pseudopolyposis of colon	0.996	0.004	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.996	0.004	0.000
C44.5 Skin of trunk	0.995	0.005	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.985	0.005	0.010
K50.1 Crohn's disease of large intestine	0.994	0.006	0.000
M05 Seropositive rheumatoid arthritis	0.994	0.006	0.000
E20-E35 Disorders of other endocrine glands	0.000	0.006	0.994
M05.9 Seropositive rheumatoid arthritis, unspecified	0.991	0.009	0.000
D86 Sarcoidosis	0.000	0.009	0.991
D50-D53 Nutritional anaemias	0.000	0.011	0.989
D86.9 Sarcoidosis, unspecified	0.000	0.011	0.989
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.013	0.987
D80-D89 Certain disorders involving the immune mechanism	0.000	0.014	0.986
Chapter II Neoplasms	0.056	0.014	0.929
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.985	0.015	0.000
D50 Iron deficiency anaemia	0.000	0.016	0.984
D50.9 Iron deficiency anaemia, unspecified	0.000	0.017	0.983
M07 Psoriatic and enteropathic arthropathies	0.983	0.017	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.978	0.019	0.002
D51 Vitamin B12 deficiency anaemia	0.000	0.020	0.980
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.974	0.026	0.000
E27 Other disorders of adrenal gland	0.000	0.027	0.973
E10.3 With ophthalmic complications	0.000	0.028	0.972
M07.3 Other psoriatic arthropathies	0.972	0.028	0.000
K90 Intestinal malabsorption	0.000	0.028	0.971
C83 Diffuse non-Hodgkin's lymphoma	0.968	0.030	0.002
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.032	0.968
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.037	0.963
D86.0 Sarcoidosis of lung	0.000	0.038	0.962
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.000	0.039	0.961
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.021	0.041	0.938
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.959	0.041	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.957	0.043	0.000
C34 Malignant neoplasm of bronchus and lung	0.000	0.046	0.953
C83.3 Large cell (diffuse)	0.953	0.047	0.000
K50.9 Crohn's disease, unspecified	0.952	0.048	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.050	0.950
C34.9 Bronchus or lung, unspecified	0.000	0.050	0.950
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.050	0.950
E27.1 Primary adrenocortical insufficiency	0.000	0.053	0.947
K51.2 Ulcerative (chronic) proctitis	0.938	0.062	0.000
E10.1 With ketoacidosis	0.000	0.062	0.938
# Top node	0.007	0.063	0.930
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.937	0.063	0.000
C44.4 Skin of scalp and neck	0.936	0.064	0.000
K51.8 Other ulcerative colitis	0.934	0.066	0.000
E21.0 Primary hyperparathyroidism	0.000	0.071	0.929
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.001	0.072	0.927
C15-C26 Malignant neoplasms of digestive organs	0.000	0.078	0.922
C44.0 Skin of lip	0.921	0.079	0.000
C80 Malignant neoplasm without specification of site	0.000	0.081	0.919
Chapter XII Diseases of the skin and subcutaneous tissue	0.007	0.083	0.909
C34.3 Lower lobe, bronchus or lung	0.000	0.085	0.915
E16 Other disorders of pancreatic internal secretion	0.000	0.085	0.915
C82.0 Small cleaved cell, follicular	0.909	0.091	0.000
L80-L99 Other disorders of the skin and subcutaneous tissue	0.000	0.092	0.908
C80.0 Malignant neoplasm, primary site unknown, so stated	0.000	0.092	0.908
C44.1 Skin of eyelid, including canthus	0.907	0.093	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.093	0.907
L91 Hypertrophic disorders of skin	0.000	0.101	0.899
C21 Malignant neoplasm of anus and anal canal	0.000	0.103	0.897
L90 Atrophic disorders of skin	0.000	0.104	0.896
C79 Secondary malignant neoplasm of other sites	0.000	0.104	0.896
L91.8 Other hypertrophic disorders of skin	0.000	0.113	0.887
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.887	0.113	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.114	0.886
L90.0 Lichen sclerosus et atrophicus	0.000	0.115	0.885
E16.2 Hypoglycaemia, unspecified	0.000	0.115	0.885
M07.30 Other psoriatic arthropathies (Multiple sites)	0.879	0.121	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.877	0.123	0.000
M06.3 Rheumatoid nodule	0.876	0.124	0.000
D86.8 Sarcoidosis of other and combined sites	0.000	0.125	0.875
E22 Hyperfunction of pituitary gland	0.000	0.126	0.874
L97 Ulcer of lower limb, not elsewhere classified	0.000	0.129	0.871
C25 Malignant neoplasm of pancreas	0.000	0.129	0.871
M07.39 Other psoriatic arthropathies (Site unspecified)	0.868	0.132	0.000
C20 Malignant neoplasm of rectum	0.000	0.139	0.861
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.860	0.139	0.000
C44.6 Skin of upper limb, including shoulder	0.858	0.142	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.857	0.143	0.000
C64-C68 Malignant neoplasms of urinary tract	0.017	0.144	0.838
K90.9 Intestinal malabsorption, unspecified	0.000	0.155	0.845
M07.36 Other psoriatic arthropathies (Lower leg)	0.844	0.156	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.840	0.160	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.711	0.161	0.127
L92 Granulomatous disorders of skin and subcutaneous tissue	0.000	0.162	0.838
C82.3 Follicular lymphoma grade IIIa	0.837	0.163	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.834	0.166	0.000
C21.0 Anus, unspecified	0.000	0.169	0.831
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.000	0.171	0.829
M45 Ankylosing spondylitis	0.828	0.172	0.000
C21.1 Anal canal	0.000	0.173	0.827
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.823	0.177	0.000
C67 Malignant neoplasm of bladder	0.001	0.181	0.818
C34.0 Main bronchus	0.000	0.181	0.819
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.817	0.183	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.817	0.183	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.815	0.185	0.000
M45-M49 Spondylopathies	0.814	0.186	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.814	0.186	0.000
C25.9 Pancreas, unspecified	0.000	0.190	0.810
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.809	0.191	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.195	0.805
D52 Folate deficiency anaemia	0.000	0.200	0.800
C34.1 Upper lobe, bronchus or lung	0.000	0.203	0.796
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.205	0.795
C79.7 Secondary malignant neoplasm of adrenal gland	0.000	0.206	0.794
C67.9 Bladder, unspecified	0.000	0.208	0.792
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.000	0.209	0.791
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.789	0.211	0.000
K90-K93 Other diseases of the digestive system	0.007	0.211	0.782
E10.8 With unspecified complications	0.000	0.212	0.788
L91.0 Keloid scar	0.000	0.216	0.784
E20 Hypoparathyroidism	0.000	0.217	0.783
E21.3 Hyperparathyroidism, unspecified	0.000	0.218	0.782
C80.9 Malignant neoplasm, unspecified	0.000	0.222	0.778
Chapter XI Diseases of the digestive system	0.007	0.223	0.770
E27.2 Addisonian crisis	0.000	0.226	0.774
L50-L54 Urticaria and erythema	0.004	0.226	0.770
K51.5 Mucosal proctocolitis	0.773	0.227	0.000
D55-D59 Haemolytic anaemias	0.000	0.232	0.767
E29 Testicular dysfunction	0.000	0.242	0.758
C23 Malignant neoplasm of gallbladder	0.000	0.243	0.756
M06.34 Rheumatoid nodule (Hand)	0.754	0.246	0.000
C79.2 Secondary malignant neoplasm of skin	0.000	0.248	0.752
K86 Other diseases of pancreas	0.000	0.250	0.750
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.749	0.250	0.001
G35 Multiple sclerosis	0.000	0.250	0.750
Chapter VI Diseases of the nervous system	0.000	0.252	0.748
C83.1 Small cleaved cell (diffuse)	0.746	0.253	0.001
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.253	0.747
E13 Other specified diabetes mellitus	0.000	0.253	0.747
K50.8 Other Crohn's disease	0.745	0.255	0.000
E10.0 With coma	0.000	0.257	0.743
E24 Cushing's syndrome	0.000	0.260	0.740
C79.6 Secondary malignant neoplasm of ovary	0.000	0.260	0.739
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.000	0.261	0.739
C79.9 Secondary malignant neoplasm, unspecified site	0.000	0.262	0.738
K86.1 Other chronic pancreatitis	0.000	0.264	0.736
E10.5 With peripheral circulatory complications	0.000	0.266	0.734
L92.0 Granuloma annulare	0.000	0.266	0.734
C84 Peripheral and cutaneous T-cell lymphomas	0.722	0.271	0.006
C82.1 Mixed small cleaved and large cell, follicular	0.728	0.272	0.000
E14 Unspecified diabetes mellitus	0.000	0.274	0.726
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.274	0.726
E10.6 With other specified complications	0.000	0.274	0.726
C82.2 Large cell, follicular	0.723	0.277	0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.000	0.277	0.723
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.721	0.277	0.001
L50 Urticaria	0.001	0.278	0.721
E50-E64 Other nutritional deficiencies	0.000	0.279	0.720
M65-M68 Disorders of synovium and tendon	0.720	0.280	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.719	0.281	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.718	0.282	0.000
M06.4 Inflammatory polyarthropathy	0.718	0.282	0.000
C44.8 Overlapping lesion of skin	0.717	0.283	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.717	0.283	0.000
M06.8 Other specified rheumatoid arthritis	0.717	0.283	0.000
M06.2 Rheumatoid bursitis	0.717	0.283	0.000
M06.1 Adult-onset Still's disease	0.717	0.283	0.000
E10.7 With multiple complications	0.000	0.283	0.717
M14 Arthropathies in other diseases classified elsewhere	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.000	0.283	0.717
M12 Other specific arthropathies	0.716	0.284	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.716	0.284	0.000
M08 Juvenile arthritis	0.716	0.284	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.716	0.284	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.716	0.284	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.716	0.284	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.716	0.284	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.716	0.284	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.716	0.284	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.716	0.284	0.000
C82.6 Cutaneous follicle centre lymphoma	0.716	0.284	0.000
C82.5 Diffuse follicle centre lymphoma	0.716	0.284	0.000
C82.4 Follicular lymphoma grade IIIb	0.716	0.284	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.284	0.716
E00 Congenital iodine-deficiency syndrome	0.000	0.284	0.716
C25.2 Tail of pancreas	0.000	0.284	0.716
E03.5 Myxoedema coma	0.000	0.285	0.715
E03.4 Atrophy of thyroid (acquired)	0.000	0.285	0.715
E03.3 Postinfectious hypothyroidism	0.000	0.285	0.715
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.285	0.715
E03.1 Congenital hypothyroidism without goitre	0.000	0.285	0.715
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.285	0.715
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.706	0.287	0.007
C95 Leukaemia of unspecified cell type	0.706	0.287	0.007
C94 Other leukaemias of specified cell type	0.706	0.287	0.007
C93 Monocytic leukaemia	0.706	0.287	0.007
C86 Other specified types of T/NK-cell lymphoma	0.706	0.287	0.007
M05.8 Other seropositive rheumatoid arthritis	0.713	0.287	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.713	0.287	0.000
M05.2 Rheumatoid vasculitis	0.713	0.287	0.000
M05.1 Rheumatoid lung disease	0.713	0.287	0.000
M05.0 Felty's syndrome	0.713	0.287	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.287	0.713
E32 Diseases of thymus	0.000	0.287	0.713
E31 Polyglandular dysfunction	0.000	0.287	0.713
E30 Disorders of puberty, not elsewhere classified	0.000	0.287	0.713
E25 Adrenogenital disorders	0.000	0.287	0.713
M46 Other inflammatory spondylopathies	0.711	0.289	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.710	0.290	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.710	0.290	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.710	0.290	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.710	0.290	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.710	0.290	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.710	0.290	0.000
D86.3 Sarcoidosis of skin	0.000	0.290	0.710
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.290	0.710
D86.1 Sarcoidosis of lymph nodes	0.000	0.290	0.710
D82 Immunodeficiency associated with other major defects	0.000	0.293	0.707
D81 Combined immunodeficiencies	0.000	0.293	0.707
E10.4 With neurological complications	0.000	0.294	0.706
L90.5 Scar conditions and fibrosis of skin	0.000	0.294	0.706
D50.1 Sideropenic dysphagia	0.000	0.294	0.705
C85.1 B-cell lymphoma, unspecified	0.705	0.295	0.001
M07.6 Other enteropathic arthropathies	0.705	0.295	0.000
M07.5 Arthropathy in ulcerative colitis	0.705	0.295	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.705	0.295	0.000
M07.2 Psoriatic spondylitis	0.705	0.295	0.000
M07.1 Arthritis mutilans	0.705	0.295	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.705	0.295	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.701	0.297	0.002
C85.0 Lymphosarcoma	0.701	0.297	0.002
D51.8 Other vitamin B12 deficiency anaemias	0.000	0.297	0.703
D51.3 Other dietary vitamin B12 deficiency anaemia	0.000	0.297	0.703
D51.2 Transcobalamin II deficiency	0.000	0.297	0.703
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.000	0.297	0.703
M11 Other crystal arthropathies	0.702	0.298	0.000
L80 Vitiligo	0.000	0.299	0.701
C67.6 Ureteric orifice	0.001	0.300	0.699
E27.5 Adrenomedullary hyperfunction	0.000	0.302	0.698
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.302	0.698
E27.0 Other adrenocortical overactivity	0.000	0.302	0.698
E27.9 Disorder of adrenal gland, unspecified	0.000	0.303	0.697
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.303	0.697
M07.38 Other psoriatic arthropathies (Other)	0.697	0.303	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.697	0.303	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.697	0.303	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.697	0.303	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.697	0.303	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.697	0.303	0.000
K90.3 Pancreatic steatorrhoea	0.000	0.303	0.696
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.303	0.696
K90.1 Tropical sprue	0.000	0.303	0.696
E65-E68 Obesity and other hyperalimentation	0.000	0.304	0.696
C83.7 Burkitt's tumour	0.694	0.304	0.002
C83.6 Undifferentiated (diffuse)	0.694	0.304	0.002
C83.5 Lymphoblastic (diffuse)	0.694	0.304	0.002
C83.4 Immunoblastic (diffuse)	0.694	0.304	0.002
C83.2 Mixed small and large cell (diffuse)	0.694	0.304	0.002
L40-L45 Papulosquamous disorders	0.009	0.305	0.686
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.305	0.695
C88 Malignant immunoproliferative diseases	0.687	0.306	0.007
E05.5 Thyroid crisis or storm	0.000	0.306	0.694
E05.4 Thyrotoxicosis factitia	0.000	0.306	0.694
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.306	0.694
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.306	0.694
M06.37 Rheumatoid nodule (Ankle and foot)	0.694	0.306	0.000
C44.9 Malignant neoplasm of skin, unspecified	0.693	0.307	0.000
K90.8 Other intestinal malabsorption	0.000	0.308	0.692
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.310	0.690
E21.4 Other specified disorders of parathyroid gland	0.000	0.310	0.690
E21.2 Other hyperparathyroidism	0.000	0.310	0.690
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.688	0.311	0.000
Chapter XXII Codes for special purposes	0.005	0.312	0.683
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.015	0.312	0.673
C31 Malignant neoplasm of accessory sinuses	0.015	0.312	0.673
C37 Malignant neoplasm of thymus	0.015	0.312	0.673
C33 Malignant neoplasm of trachea	0.015	0.312	0.673
C22.9 Liver, unspecified	0.000	0.313	0.687
G80-G83 Cerebral palsy and other paralytic syndromes	0.000	0.315	0.685
C34.8 Overlapping lesion of bronchus and lung	0.000	0.316	0.684
E15 Nondiabetic hypoglycaemic coma	0.000	0.318	0.681
E03.8 Other specified hypothyroidism	0.000	0.319	0.681
C22.1 Intrahepatic bile duct carcinoma	0.000	0.321	0.679
E05.9 Thyrotoxicosis, unspecified	0.000	0.323	0.677
E05.8 Other thyrotoxicosis	0.000	0.325	0.674
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.326	0.674
C32 Malignant neoplasm of larynx	0.011	0.328	0.661
Chapter XVI Certain conditions originating in the perinatal period	0.005	0.328	0.667
D53 Other nutritional anaemias	0.000	0.329	0.671
C85.7 Other specified types of non-Hodgkin's lymphoma	0.668	0.330	0.002
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.000	0.332	0.668
D59 Acquired haemolytic anaemia	0.000	0.333	0.667
E40-E46 Malnutrition	0.000	0.333	0.667
C40-C41 Malignant neoplasms of bone and articular cartilage	0.043	0.336	0.621
M65 Synovitis and tenosynovitis	0.664	0.336	0.000
D52.9 Folate deficiency anaemia, unspecified	0.000	0.336	0.664
C25.1 Body of pancreas	0.000	0.338	0.662
L93 Lupus erythematosus	0.000	0.342	0.658
L89 Decubitus ulcer	0.000	0.344	0.656
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.344	0.656
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.344	0.656
E16.4 Abnormal secretion of gastrin	0.000	0.344	0.656
E16.3 Increased secretion of glucagon	0.000	0.344	0.656
E16.1 Other hypoglycaemia	0.000	0.344	0.656
C22.0 Liver cell carcinoma	0.000	0.345	0.655
C19 Malignant neoplasm of rectosigmoid junction	0.000	0.346	0.654
C30 Malignant neoplasm of nasal cavity and middle ear	0.015	0.346	0.638
L40 Psoriasis	0.009	0.347	0.644
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.000	0.349	0.651
L87 Transepidermal elimination disorders	0.000	0.349	0.651
L86 Keratoderma in diseases classified elsewhere	0.000	0.349	0.651
L83 Acanthosis nigricans	0.000	0.351	0.649
C34.2 Middle lobe, bronchus or lung	0.000	0.353	0.646
K52 Other non-infective gastro-enteritis and colitis	0.647	0.353	0.000
L50.0 Allergic urticaria	0.001	0.355	0.644
K86.3 Pseudocyst of pancreas	0.000	0.356	0.644
M45.X2 Ankylosing spondylitis (Cervical region)	0.644	0.356	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.000	0.357	0.643
C21.2 Cloacogenic zone	0.000	0.357	0.643
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.357	0.643
L90.9 Atrophic disorder of skin, unspecified	0.000	0.357	0.643
L90.8 Other atrophic disorders of skin	0.000	0.357	0.643
L90.6 Striae atrophicae	0.000	0.357	0.643
L90.4 Acrodermatitis chronica atrophicans	0.000	0.357	0.643
L90.3 Atrophoderma of Pasini and Pierini	0.000	0.357	0.643
L90.2 Anetoderma of Jadassohn-Pellizzari	0.000	0.357	0.643
L90.1 Anetoderma of Schweninger-Buzzi	0.000	0.357	0.643
C38 Malignant neoplasm of heart, mediastinum and pleura	0.016	0.359	0.626
E10.2 With renal complications	0.000	0.360	0.640
C76 Malignant neoplasm of other and ill-defined sites	0.001	0.360	0.639
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.000	0.361	0.639
C66 Malignant neoplasm of ureter	0.010	0.361	0.628
G83 Other paralytic syndromes	0.000	0.362	0.638
D80 Immunodeficiency with predominantly antibody defects	0.000	0.364	0.635
M65.9 Synovitis and tenosynovitis, unspecified	0.635	0.365	0.000
E34 Other endocrine disorders	0.000	0.366	0.634
M00-M03 Infectious arthropathies	0.633	0.367	0.000
E20.9 Hypoparathyroidism, unspecified	0.000	0.368	0.632
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.632	0.368	0.000
C79.8 Secondary malignant neoplasm of other specified sites	0.000	0.369	0.631
E07 Other disorders of thyroid	0.000	0.370	0.630
D83 Common variable immunodeficiency	0.000	0.370	0.630
M06.39 Rheumatoid nodule (Site unspecified)	0.628	0.372	0.000
M06.38 Rheumatoid nodule (Other)	0.628	0.372	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.628	0.372	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.628	0.372	0.000
M06.33 Rheumatoid nodule (Forearm)	0.628	0.372	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.628	0.372	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.628	0.372	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.628	0.372	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.373	0.627
E22.8 Other hyperfunction of pituitary gland	0.000	0.373	0.627
L50.9 Urticaria, unspecified	0.001	0.374	0.626
C25.8 Overlapping lesion of pancreas	0.000	0.376	0.624
C25.7 Other parts of pancreas	0.000	0.376	0.624
C25.4 Endocrine pancreas	0.000	0.376	0.624
E22.1 Hyperprolactinaemia	0.000	0.376	0.624
M40-M43 Deforming dorsopathies	0.623	0.377	0.000
E27.8 Other specified disorders of adrenal gland	0.000	0.377	0.623
L88 Pyoderma gangrenosum	0.000	0.378	0.622
C67.4 Posterior wall of bladder	0.001	0.378	0.621
C25.0 Head of pancreas	0.000	0.379	0.621
L40.9 Psoriasis, unspecified	0.000	0.381	0.619
L10-L14 Bullous disorders	0.006	0.381	0.614
L60-L75 Disorders of skin appendages	0.002	0.381	0.617
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.043	0.381	0.575
C67.3 Anterior wall of bladder	0.001	0.382	0.617
K83 Other diseases of biliary tract	0.000	0.383	0.617
C68 Malignant neoplasm of other and unspecified urinary organs	0.013	0.386	0.601
E22.0 Acromegaly and pituitary gigantism	0.000	0.388	0.612
K86.8 Other specified diseases of pancreas	0.000	0.390	0.610
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.000	0.393	0.607
E53 Deficiency of other B group vitamins	0.000	0.393	0.606
C43 Malignant melanoma of skin	0.590	0.394	0.016
C17 Malignant neoplasm of small intestine	0.000	0.394	0.605
C83.0 Small cell (diffuse)	0.603	0.395	0.002
M49 Spondylopathies in diseases classified elsewhere	0.602	0.398	0.000
L95 Vasculitis limited to skin, not elsewhere classified	0.000	0.399	0.601
L92.2 Granuloma faciale [eosinophilic granuloma of skin]	0.000	0.399	0.601
L92.1 Necrobiosis lipoidica, not elsewhere classified	0.000	0.399	0.601
C81 Hodgkin's disease	0.592	0.399	0.008
E06 Thyroiditis	0.000	0.402	0.598
C67.8 Overlapping lesion of bladder	0.001	0.403	0.596
D59.1 Other autoimmune haemolytic anaemias	0.000	0.404	0.595
L89.2 Stage III decubitus ulcer	0.000	0.405	0.595
C22.7 Other specified carcinomas of liver	0.000	0.406	0.594
C22.4 Other sarcomas of liver	0.000	0.406	0.594
C22.3 Angiosarcoma of liver	0.000	0.406	0.594
C22.2 Hepatoblastoma	0.000	0.406	0.594
C25.3 Pancreatic duct	0.000	0.406	0.594
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.594	0.406	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.594	0.406	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.594	0.406	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.594	0.406	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.594	0.406	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.594	0.406	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.594	0.406	0.000
J45 Asthma	0.001	0.410	0.589
E29.1 Testicular hypofunction	0.000	0.411	0.589
C67.7 Urachus	0.001	0.413	0.586
C67.0 Trigone of bladder	0.001	0.413	0.586
E14.9 Without complications	0.000	0.413	0.587
K86.9 Disease of pancreas, unspecified	0.000	0.415	0.585
C67.5 Bladder neck	0.001	0.416	0.583
C60-C63 Malignant neoplasms of male genital organs	0.016	0.417	0.567
M60-M63 Disorders of muscles	0.581	0.419	0.000
L94 Other localised connective tissue disorders	0.000	0.420	0.579
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.030	0.420	0.549
C26 Malignant neoplasm of other and ill-defined digestive organs	0.000	0.421	0.579
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.577	0.423	0.000
M46.1 Sacro-iliitis, not elsewhere classified	0.576	0.424	0.000
C43.6 Malignant melanoma of upper limb, including shoulder	0.573	0.426	0.002
L60 Nail disorders	0.001	0.426	0.573
D52.8 Other folate deficiency anaemias	0.000	0.426	0.573
D52.1 Drug-induced folate deficiency anaemia	0.000	0.426	0.573
D52.0 Dietary folate deficiency anaemia	0.000	0.426	0.573
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.000	0.429	0.571
L40.0 Psoriasis vulgaris	0.003	0.430	0.566
C67.2 Lateral wall of bladder	0.001	0.431	0.568
D84 Other immunodeficiencies	0.001	0.433	0.567
K93 Disorders of other digestive organs in diseases classified elsewhere	0.005	0.434	0.561
E13.9 Without complications	0.000	0.435	0.565
M46.9 Inflammatory spondylopathy, unspecified	0.565	0.435	0.000
L20-L30 Dermatitis and eczema	0.002	0.435	0.562
L91.9 Hypertrophic disorder of skin, unspecified	0.000	0.437	0.563
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.563	0.437	0.000
L92.8 Other granulomatous disorders of skin and subcutaneous tissue	0.000	0.438	0.562
E20.8 Other hypoparathyroidism	0.000	0.438	0.562
E20.1 Pseudohypoparathyroidism	0.000	0.438	0.562
E20.0 Idiopathic hypoparathyroidism	0.000	0.438	0.562
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.001	0.439	0.561
C65 Malignant neoplasm of renal pelvis	0.013	0.441	0.547
E24.9 Cushing's syndrome, unspecified	0.000	0.442	0.558
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.002	0.444	0.554
L54 Erythema in diseases classified elsewhere	0.003	0.445	0.552
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.000	0.449	0.551
D57 Sickle-cell disorders	0.000	0.449	0.550
D55 Anaemia due to enzyme disorders	0.000	0.449	0.550
L52 Erythema nodosum	0.003	0.452	0.545
M11.9 Crystal arthropathy, unspecified	0.548	0.452	0.000
L60.0 Ingrowing nail	0.000	0.454	0.546
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.000	0.456	0.544
G30-G32 Other degenerative diseases of the nervous system	0.000	0.456	0.544
K83.0 Cholangitis	0.000	0.456	0.544
E29.9 Testicular dysfunction, unspecified	0.000	0.456	0.543
E29.8 Other testicular dysfunction	0.000	0.456	0.543
E29.0 Testicular hyperfunction	0.000	0.456	0.543
M46.2 Osteomyelitis of vertebra	0.543	0.457	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.542	0.458	0.000
G81 Hemiplegia	0.000	0.458	0.542
K83.1 Obstruction of bile duct	0.000	0.460	0.540
G83.1 Monoplegia of lower limb	0.000	0.462	0.538
K52.1 Toxic gastro-enteritis and colitis	0.538	0.462	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.530	0.463	0.007
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.463	0.537
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.000	0.463	0.536
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.536	0.464	0.000
G36 Other acute disseminated demyelination	0.000	0.464	0.535
E13.8 With unspecified complications	0.000	0.464	0.535
E13.7 With multiple complications	0.000	0.464	0.535
E13.6 With other specified complications	0.000	0.464	0.535
E13.5 With peripheral circulatory complications	0.000	0.464	0.535
E13.4 With neurological complications	0.000	0.464	0.535
E13.3 With ophthalmic complications	0.000	0.464	0.535
E13.2 With renal complications	0.000	0.464	0.535
E13.1 With ketoacidosis	0.000	0.464	0.535
E13.0 With coma	0.000	0.464	0.535
L53 Other erythematous conditions	0.002	0.465	0.533
M66 Spontaneous rupture of synovium and tendon	0.534	0.465	0.000
C84.5 Other and unspecified T-cell lymphomas	0.528	0.467	0.004
M91-M94 Chondropathies	0.531	0.469	0.000
E24.8 Other Cushing's syndrome	0.000	0.469	0.530
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.469	0.530
E24.3 Ectopic ACTH syndrome	0.000	0.469	0.530
E24.2 Drug-induced Cushing's syndrome	0.000	0.469	0.530
E24.1 Nelson's syndrome	0.000	0.469	0.530
E24.0 Pituitary-dependent Cushing's disease	0.000	0.469	0.530
M10 Gout	0.530	0.470	0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.000	0.470	0.530
E53.8 Deficiency of other specified B group vitamins	0.000	0.472	0.528
C84.4 Peripheral T-cell lymphoma	0.524	0.472	0.004

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations