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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72881062
log Bayes Factor = 15.7439
Chromosome 6   position 56,801,308  (GRCh37) Explore rs72881062 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
0.999 0.001 0.000
I30-I52 Other forms of heart disease
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.997 0.003 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.996 0.004 0.000
Chapter XXI Factors influencing health status and contact with health services
0.995 0.005 0.000
I25.1 Atherosclerotic heart disease
0.993 0.007 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.993 0.007 0.000
I21 Acute myocardial infarction
0.992 0.008 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.990 0.010 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.990 0.010 0.000
Z92 Personal history of medical treatment
0.988 0.012 0.000
O60-O75 Complications of labour and delivery
0.981 0.019 0.000
Chapter XX External causes of morbidity and mortality
0.975 0.025 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.974 0.026 0.000
O00-O08 Pregnancy with abortive outcome
0.973 0.027 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.970 0.030 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.964 0.036 0.000
I20 Angina pectoris
0.961 0.039 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.957 0.043 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.956 0.044 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.950 0.050 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.946 0.054 0.000
Chapter VIII Diseases of the ear and mastoid process
0.946 0.054 0.000
I42 Cardiomyopathy
0.946 0.054 0.000
R00 Abnormalities of heart beat
0.946 0.054 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.944 0.056 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.943 0.057 0.000
F30-F39 Mood [affective] disorders
0.942 0.058 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.941 0.059 0.000
Z80 Family history of malignant neoplasm
0.934 0.066 0.000
R00.2 Palpitations
0.934 0.066 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.932 0.068 0.000
I51 Complications and ill-defined descriptions of heart disease
0.931 0.069 0.000
I60-I69 Cerebrovascular diseases
0.930 0.070 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.922 0.078 0.000
I20.9 Angina pectoris, unspecified
0.918 0.082 0.000
O02 Other abnormal products of conception
0.915 0.085 0.000
T42.4 Benzodiazepines
0.911 0.089 0.000
O03 Spontaneous abortion
0.911 0.089 0.000
R00.1 Bradycardia, unspecified
0.910 0.090 0.000
H65-H75 Diseases of middle ear and mastoid
0.907 0.093 0.000
O70 Perineal laceration during delivery
0.902 0.098 0.000
I50 Heart failure
0.902 0.098 0.000
Z80.3 Family history of malignant neoplasm of breast
0.897 0.103 0.000
Z99.1 Dependence on respirator
0.897 0.103 0.000
S60-S69 Injuries to the wrist and hand
0.896 0.104 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.895 0.105 0.000
Z99.3 Dependence on wheelchair
0.894 0.106 0.000
I46 Cardiac arrest
0.892 0.108 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.891 0.109 0.000
I05-I09 Chronic rheumatic heart diseases
0.891 0.109 0.000
I34 Nonrheumatic mitral valve disorders
0.891 0.109 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.889 0.110 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.886 0.114 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.884 0.116 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.881 0.119 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.880 0.120 0.000
I35 Nonrheumatic aortic valve disorders
0.879 0.121 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.875 0.125 0.000
O02.1 Missed abortion
0.873 0.127 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.868 0.132 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.866 0.134 0.000
F32 Depressive episode
0.866 0.134 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.865 0.135 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.865 0.135 0.000
I25.2 Old myocardial infarction
0.864 0.136 0.000
I63 Cerebral infarction
0.863 0.137 0.000
F60-F69 Disorders of adult personality and behaviour
0.860 0.139 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.860 0.140 0.000
F40 Phobic anxiety disorders
0.859 0.141 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.858 0.142 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.854 0.146 0.000
O03.9 Complete or unspecified, without complication
0.852 0.148 0.000
Z92.0 Personal history of contraception
0.852 0.148 0.000
I42.0 Dilated cardiomyopathy
0.852 0.148 0.000
F10.1 Harmful use
0.851 0.149 0.000
Z95.2 Presence of prosthetic heart valve
0.851 0.149 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.850 0.150 0.000
Z94 Transplanted organ and tissue status
0.846 0.154 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.842 0.158 0.000
O70.0 First degree perineal laceration during delivery
0.842 0.158 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.839 0.161 0.000
I50.1 Left ventricular failure
0.838 0.162 0.000
O80-O84 Delivery
0.838 0.162 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.833 0.167 0.000
Z83 Family history of other specific disorders
0.832 0.168 0.000
Y44 Agents primarily affecting blood constituents
0.831 0.169 0.000
Y52 Agents primarily affecting the cardiovascular system
0.831 0.169 0.000
O73 Retained placenta and membranes, without haemorrhage
0.828 0.172 0.000
R42 Dizziness and giddiness
0.826 0.174 0.000
Z95.1 Presence of aortocoronary bypass graft
0.826 0.174 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.823 0.177 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.821 0.179 0.000
Chapter II Neoplasms
0.821 0.179 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.818 0.182 0.000
D69 Purpura and other haemorrhagic conditions
0.815 0.185 0.000
I51.7 Cardiomegaly
0.815 0.185 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.814 0.186 0.000
R04 Haemorrhage from respiratory passages
0.809 0.191 0.000
I63.9 Cerebral infarction, unspecified
0.808 0.192 0.000
F40.2 Specific (isolated) phobias
0.806 0.194 0.000
Chapter XXII Codes for special purposes
0.806 0.194 0.000
I45 Other conduction disorders
0.806 0.194 0.000
Z99.2 Dependence on renal dialysis
0.805 0.195 0.000
Z91.5 Personal history of self-harm
0.802 0.198 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.802 0.198 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.798 0.202 0.000
F80-F89 Disorders of psychological development
0.795 0.205 0.000
I34.0 Mitral (valve) insufficiency
0.791 0.209 0.000
O36 Maternal care for other known or suspected foetal problems
0.791 0.209 0.000
I08 Multiple valve diseases
0.789 0.210 0.000
H74 Other disorders of middle ear and mastoid
0.786 0.214 0.000
F99-F99 Unspecified mental disorder
0.786 0.214 0.000
H72 Perforation of tympanic membrane
0.786 0.214 0.000
X60-X84 Intentional self-harm
0.782 0.218 0.000
Z95.3 Presence of xenogenic heart valve
0.782 0.218 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.781 0.219 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.780 0.220 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.780 0.220 0.000
I22 Subsequent myocardial infarction
0.779 0.221 0.000
I10-I15 Hypertensive diseases
0.779 0.221 0.000
Y57 Other and unspecified drugs and medicaments
0.778 0.222 0.000
I71 Aortic aneurysm and dissection
0.778 0.222 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.777 0.223 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.777 0.223 0.000
F33 Recurrent depressive disorder
0.776 0.224 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.775 0.225 0.000
X20-X29 Contact with venomous animals and plants
0.771 0.229 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.770 0.230 0.000
I42.9 Cardiomyopathy, unspecified
0.770 0.230 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.769 0.231 0.000
D69.6 Thrombocytopenia, unspecified
0.768 0.232 0.000
I20.0 Unstable angina
0.766 0.234 0.000
I46.0 Cardiac arrest with successful resuscitation
0.766 0.234 0.000
S50-S59 Injuries to the elbow and forearm
0.765 0.235 0.000
Z89 Acquired absence of limb
0.765 0.235 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.765 0.235 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.764 0.236 0.000
R02 Gangrene, not elsewhere classified
0.764 0.236 0.000
I51.8 Other ill-defined heart diseases
0.762 0.238 0.000
F60 Specific personality disorders
0.761 0.239 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.761 0.239 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.761 0.239 0.000
I20.1 Angina pectoris with documented spasm
0.760 0.240 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.759 0.240 0.000
I31 Other diseases of pericardium
0.759 0.241 0.000
O80 Single spontaneous delivery
0.759 0.241 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.757 0.243 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.757 0.243 0.000
Z80.6 Family history of leukaemia
0.756 0.244 0.000
H73 Other disorders of tympanic membrane
0.755 0.245 0.000
O61 Failed induction of labour
0.755 0.245 0.000
I51.0 Cardiac septal defect, acquired
0.753 0.247 0.000
F41 Other anxiety disorders
0.752 0.248 0.000
Z81 Family history of mental and behavioural disorders
0.752 0.248 0.000
R26 Abnormalities of gait and mobility
0.752 0.248 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.750 0.250 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.750 0.250 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.750 0.250 0.000
R01 Cardiac murmurs and other cardiac sounds
0.748 0.252 0.000
H90-H95 Other disorders of ear
0.747 0.253 0.000
T66-T78 Other and unspecified effects of external causes
0.747 0.253 0.000
S60 Superficial injury of wrist and hand
0.745 0.255 0.000
I42.2 Other hypertrophic cardiomyopathy
0.744 0.256 0.000
S62 Fracture at wrist and hand level
0.743 0.257 0.000
R47-R49 Symptoms and signs involving speech and voice
0.743 0.257 0.000
Y44.2 Anticoagulants
0.742 0.258 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.742 0.258 0.000
F03 Unspecified dementia
0.741 0.259 0.000
O63 Long labour
0.741 0.259 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.740 0.260 0.000
I46.9 Cardiac arrest, unspecified
0.739 0.261 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.738 0.262 0.000
S64 Injury of nerves at wrist and hand level
0.738 0.262 0.000
I35.1 Aortic (valve) insufficiency
0.737 0.263 0.000
D68 Other coagulation defects
0.737 0.263 0.000
R04.0 Epistaxis
0.736 0.264 0.000
T51 Toxic effect of alcohol
0.731 0.269 0.000
I05 Rheumatic mitral valve diseases
0.731 0.269 0.000
Z95.4 Presence of other heart-valve replacement
0.729 0.271 0.000
F32.8 Other depressive episodes
0.728 0.272 0.000
H71 Cholesteatoma of middle ear
0.728 0.272 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.726 0.274 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.726 0.274 0.000
H60-H62 Diseases of external ear
0.725 0.275 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.724 0.276 0.000
O16 Unspecified maternal hypertension
0.724 0.276 0.000
W20-W49 Exposure to inanimate mechanical forces
0.723 0.277 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.722 0.278 0.000
F32.1 Moderate depressive episode
0.720 0.280 0.000
V10-V19 Pedal cyclist injured in transport accident
0.720 0.280 0.000
Y43 Primarily systemic agents
0.719 0.281 0.000
H66 Suppurative and unspecified otitis media
0.719 0.281 0.000
R00.0 Tachycardia, unspecified
0.719 0.281 0.000
O73.0 Retained placenta, without haemorrhage
0.718 0.282 0.000
R03.1 Nonspecific low blood-pressure reading
0.717 0.283 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.3 Aneurysm of heart
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
O85-O92 Complications predominantly related to the puerperium
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.716 0.283 0.000
F70-F79 Mental retardation
0.716 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.284 0.000
I48 Atrial fibrillation and flutter
0.716 0.284 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.284 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.284 0.000
I40 Acute myocarditis
0.716 0.284 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.284 0.000
I37 Pulmonary valve disorders
0.716 0.284 0.000
I36 Nonrheumatic tricuspid valve disorders
0.716 0.284 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.284 0.000
I30 Acute pericarditis
0.716 0.284 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.716 0.284 0.000
T33-T35 Frostbite
0.715 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.285 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.715 0.285 0.000
T00-T07 Injuries involving multiple body regions
0.715 0.285 0.000
S10-S19 Injuries to the neck
0.715 0.285 0.000
O43 Placental disorders
0.715 0.285 0.000
Z92.8 Personal history of other medical treatment
0.714 0.285 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.714 0.286 0.000
Z84 Family history of other conditions
0.714 0.286 0.000
I67 Other cerebrovascular diseases
0.714 0.286 0.000
O03.4 Incomplete, without complication
0.714 0.286 0.000
T39.1 4-Aminophenol derivatives
0.713 0.287 0.000
O23 Infections of genito-urinary tract in pregnancy
0.712 0.288 0.000
O36.5 Maternal care for poor foetal growth
0.712 0.288 0.000
I25.5 Ischaemic cardiomyopathy
0.711 0.289 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.711 0.289 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.711 0.289 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.710 0.290 0.000
F43 Reaction to severe stress, and adjustment disorders
0.710 0.290 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.710 0.290 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.710 0.290 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.710 0.290 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.710 0.290 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.710 0.290 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.710 0.290 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.710 0.290 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.710 0.290 0.000
T36 Poisoning by systemic antibiotics
0.710 0.290 0.000
Z92.9 Personal history of medical treatment, unspecified
0.709 0.291 0.000
Z92.5 Personal history of rehabilitation measures
0.709 0.291 0.000
F31 Bipolar affective disorder
0.708 0.292 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.707 0.293 0.000
O00 Ectopic pregnancy
0.707 0.293 0.000
V20-V29 Motorcycle rider injured in transport accident
0.707 0.293 0.000
S90-S99 Injuries to the ankle and foot
0.706 0.294 0.000
O80.9 Single spontaneous delivery, unspecified
0.705 0.295 0.000
I12 Hypertensive renal disease
0.704 0.296 0.000
O74 Complications of anaesthesia during labour and delivery
0.703 0.297 0.000
O71 Other obstetric trauma
0.703 0.297 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.703 0.297 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.703 0.297 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.703 0.297 0.000
O62 Abnormalities of forces of labour
0.703 0.297 0.000
O60 Preterm delivery
0.703 0.297 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.702 0.297 0.000
Z83.5 Family history of eye and ear disorders
0.702 0.298 0.000
Z94.0 Kidney transplant status
0.702 0.298 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.700 0.300 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.699 0.301 0.000
Y35-Y36 Legal intervention and operations of war
0.699 0.301 0.000
Y10-Y34 Event of undetermined intent
0.699 0.301 0.000
Y00-Y09 Assault
0.699 0.301 0.000
X85-X99 Assault
0.699 0.301 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.699 0.301 0.000
X50-X57 Overexertion, travel and privation
0.699 0.301 0.000
X30-X39 Exposure to forces of nature
0.699 0.301 0.000
X10-X19 Contact with heat and hot substances
0.699 0.301 0.000
X00-X09 Exposure to smoke, fire and flames
0.699 0.301 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.699 0.301 0.000
W75-W84 Other accidental threats to breathing
0.699 0.301 0.000
W65-W74 Accidental drowning and submersion
0.699 0.301 0.000
W50-W64 Exposure to animate mechanical forces
0.699 0.301 0.000
V98-V99 Other and unspecified transport accidents
0.699 0.301 0.000
V95-V97 Air and space transport accidents
0.699 0.301 0.000
V90-V94 Water transport accidents
0.699 0.301 0.000
V80-V89 Other land transport accidents
0.699 0.301 0.000
V70-V79 Bus occupant injured in transport accident
0.699 0.301 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.699 0.301 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.699 0.301 0.000
V40-V49 Car occupant injured in transport accident
0.699 0.301 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.699 0.301 0.000
V01-V09 Pedestrian injured in transport accident
0.699 0.301 0.000
Q23 Congenital malformations of aortic and mitral valves
0.699 0.301 0.000
Z99.9 Dependence on unspecified enabling machine and device
0.698 0.302 0.000
Z99.4 Dependence on artificial heart
0.698 0.302 0.000
Z99.0 Dependence on aspirator
0.698 0.302 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.698 0.302 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.697 0.302 0.000
O07 Failed attempted abortion
0.697 0.302 0.000
O06 Unspecified abortion
0.697 0.302 0.000
O05 Other abortion
0.697 0.302 0.000
O01 Hydatidiform mole
0.697 0.302 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.697 0.303 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.696 0.304 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.696 0.304 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.695 0.305 0.000
I34.1 Mitral (valve) prolapse
0.694 0.306 0.000
O21 Excessive vomiting in pregnancy
0.693 0.307 0.000
I33 Acute and subacute endocarditis
0.692 0.308 0.000
D00-D09 In situ neoplasms
0.692 0.308 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.692 0.308 0.000
S20-S29 Injuries to the thorax
0.689 0.311 0.000
O66 Other obstructed labour
0.688 0.311 0.000
F10.2 Dependence syndrome
0.687 0.313 0.000
O72 Postpartum haemorrhage
0.687 0.313 0.000
T43.2 Other and unspecified antidepressants
0.686 0.314 0.000
Y59 Other and unspecified vaccines and biological substances
0.686 0.314 0.000
Y58 Bacterial vaccines
0.686 0.314 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.686 0.314 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.686 0.314 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.686 0.314 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.686 0.314 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.686 0.314 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.686 0.314 0.000
Y48 Anaesthetics and therapeutic gases
0.686 0.314 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.686 0.314 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.686 0.314 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.686 0.314 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.685 0.315 0.000
Z80.8 Family history of malignant neoplasm of other organs or systems
0.685 0.315 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.685 0.315 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.684 0.316 0.000
I08.0 Disorders of both mitral and aortic valves
0.684 0.316 0.000
O48 Prolonged pregnancy
0.684 0.316 0.000
T79-T79 Certain early complications of trauma
0.682 0.318 0.000
O41 Other disorders of amniotic fluid and membranes
0.682 0.318 0.000
I60 Subarachnoid haemorrhage
0.681 0.318 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.681 0.319 0.000
S80-S89 Injuries to the knee and lower leg
0.681 0.319 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.680 0.319 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.680 0.320 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.680 0.320 0.000
Z94.4 Liver transplant status
0.679 0.321 0.000
I42.8 Other cardiomyopathies
0.678 0.322 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.678 0.322 0.000
I42.6 Alcoholic cardiomyopathy
0.678 0.322 0.000
I42.5 Other restrictive cardiomyopathy
0.678 0.322 0.000
I42.4 Endocardial fibroelastosis
0.678 0.322 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.678 0.322 0.000
D45 Polycythaemia vera
0.677 0.323 0.000
H92 Otalgia and effusion of ear
0.677 0.323 0.000
W00-W19 Falls
0.676 0.324 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.676 0.324 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.676 0.324 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.676 0.324 0.000
T42.3 Barbiturates
0.676 0.324 0.000
T42.2 Succinimides and oxazolidinediones
0.676 0.324 0.000
T42.1 Iminostilbenes
0.676 0.324 0.000
T42.0 Hydantoin derivatives
0.676 0.324 0.000
T90 Sequelae of injuries of head
0.675 0.324 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.675 0.325 0.000
F38 Other mood [affective] disorders
0.675 0.325 0.000
F34 Persistent mood [affective] disorders
0.675 0.325 0.000
F30 Manic episode
0.675 0.325 0.000
F39 Unspecified mood [affective] disorder
0.675 0.325 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.673 0.327 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.672 0.328 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.672 0.328 0.000
T93 Sequelae of injuries of lower limb
0.672 0.328 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.671 0.328 0.000
I51.9 Heart disease, unspecified
0.670 0.330 0.000
Y40 Systemic antibiotics
0.670 0.330 0.000
Q50-Q56 Congenital malformations of genital organs
0.670 0.330 0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues
0.670 0.330 0.000
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs
0.670 0.330 0.000
D55-D59 Haemolytic anaemias
0.670 0.330 0.000
I45.9 Conduction disorder, unspecified
0.669 0.330 0.000
F48 Other neurotic disorders
0.668 0.331 0.000
F44 Dissociative [conversion] disorders
0.668 0.331 0.000
F42 Obsessive-compulsive disorder
0.668 0.331 0.000
F01 Vascular dementia
0.668 0.332 0.000
O70.1 Second degree perineal laceration during delivery
0.668 0.332 0.000
I51.6 Cardiovascular disease, unspecified
0.667 0.333 0.000
I51.5 Myocardial degeneration
0.667 0.333 0.000
I51.4 Myocarditis, unspecified
0.667 0.333 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.667 0.333 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.667 0.333 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.667 0.333 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.667 0.333 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.667 0.333 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.666 0.334 0.000
I49 Other cardiac arrhythmias
0.666 0.334 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.664 0.335 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.662 0.338 0.000
T39.0 Salicylates
0.662 0.338 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.661 0.339 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.661 0.339 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.661 0.339 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.661 0.339 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.661 0.339 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.661 0.339 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.661 0.339 0.000
F11 Mental and behavioural disorders due to use of opioids
0.661 0.339 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.659 0.340 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.659 0.341 0.000
I21.4 Acute subendocardial myocardial infarction
0.658 0.342 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.657 0.342 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.657 0.343 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.656 0.344 0.000
O02.9 Abnormal product of conception, unspecified
0.656 0.344 0.000
O02.8 Other specified abnormal products of conception
0.656 0.344 0.000
O02.0 Blighted ovum and nonhydatidiform mole
0.656 0.344 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.656 0.344 0.000
O75.2 Pyrexia during labour, not elsewhere classified
0.655 0.345 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.654 0.346 0.000
Z99.8 Dependence on other enabling machines and devices
0.654 0.346 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.653 0.347 0.000
O20 Haemorrhage in early pregnancy
0.653 0.347 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.653 0.347 0.000
O03.8 Complete or unspecified, with other and unspecified complications
0.653 0.347 0.000
O03.7 Complete or unspecified, complicated by embolism
0.653 0.347 0.000
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage
0.653 0.347 0.000
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection
0.653 0.347 0.000
O03.3 Incomplete, with other and unspecified complications
0.653 0.347 0.000
O03.2 Incomplete, complicated by embolism
0.653 0.347 0.000
O03.1 Incomplete, complicated by delayed or excessive haemorrhage
0.653 0.347 0.000
O03.0 Incomplete, complicated by genital tract and pelvic infection
0.653 0.347 0.000
I50.0 Congestive heart failure
0.652 0.347 0.000
Z83.3 Family history of diabetes mellitus
0.651 0.349 0.000
I35.9 Aortic valve disorder, unspecified
0.651 0.349 0.000
Y57.9 Drug or medicament, unspecified
0.650 0.350 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.650 0.350 0.000
H70 Mastoiditis and related conditions
0.650 0.350 0.000
H69 Other disorders of Eustachian tube
0.650 0.350 0.000
H68 Eustachian salpingitis and obstruction
0.650 0.350 0.000
H67 Otitis media in diseases classified elsewhere
0.650 0.350 0.000
I12.0 Hypertensive renal disease with renal failure
0.650 0.350 0.000
F60.3 Emotionally unstable personality disorder
0.650 0.350 0.000
F81 Specific developmental disorders of scholastic skills
0.649 0.351 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.648 0.352 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.648 0.352 0.000
Q60-Q64 Congenital malformations of the urinary system
0.648 0.352 0.000
O70.9 Perineal laceration during delivery, unspecified
0.647 0.353 0.000
O70.3 Fourth degree perineal laceration during delivery
0.647 0.353 0.000
O70.2 Third degree perineal laceration during delivery
0.647 0.353 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.647 0.353 0.000
H73.8 Other specified disorders of tympanic membrane
0.647 0.353 0.000
I31.9 Disease of pericardium, unspecified
0.647 0.353 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.646 0.354 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.644 0.356 0.000
Z82.3 Family history of stroke
0.644 0.356 0.000
I47 Paroxysmal tachycardia
0.644 0.356 0.000
S67 Crushing injury of wrist and hand
0.643 0.357 0.000
S65 Injury of blood vessels at wrist and hand level
0.643 0.357 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.643 0.357 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.642 0.358 0.000
Q80-Q89 Other congenital malformations
0.642 0.358 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.642 0.358 0.000
Q35-Q37 Cleft lip and cleft palate
0.642 0.358 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.642 0.358 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.642 0.358 0.000
Q00-Q07 Congenital malformations of the nervous system
0.642 0.358 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.641 0.359 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.641 0.359 0.000
I45.6 Preexcitation syndrome
0.641 0.359 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.640 0.360 0.000
T51.0 Ethanol
0.640 0.360 0.000
I46.1 Sudden cardiac death, so described
0.640 0.360 0.000
S69 Other and unspecified injuries of wrist and hand
0.639 0.361 0.000
O36.8 Maternal care for other specified foetal problems
0.639 0.361 0.000
I09 Other rheumatic heart diseases
0.639 0.361 0.000
I06 Rheumatic aortic valve diseases
0.639 0.361 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.639 0.361 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.639 0.361 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.639 0.361 0.000
O42 Premature rupture of membranes
0.638 0.362 0.000
T43.9 Psychotropic drug, unspecified
0.638 0.362 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.638 0.362 0.000
T43.6 Psychostimulants with abuse potential
0.638 0.362 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.638 0.362 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.638 0.362 0.000
C71 Malignant neoplasm of brain
0.638 0.362 0.000
F33.9 Recurrent depressive disorder, unspecified
0.637 0.362 0.000
H74.0 Tympanosclerosis
0.637 0.363 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.637 0.363 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.636 0.363 0.000
O75.8 Other specified complications of labour and delivery
0.637 0.363 0.000
Z97 Presence of other devices
0.636 0.364 0.000
S60.9 Superficial injury of wrist and hand, unspecified
0.636 0.364 0.000
Q24 Other congenital malformations of heart
0.636 0.364 0.000
S64.0 Injury of ulnar nerve at wrist and hand level
0.636 0.364 0.000
T87 Complications peculiar to reattachment and amputation
0.635 0.365 0.000
T86 Failure and rejection of transplanted organs and tissues
0.635 0.365 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.635 0.365 0.000
F10.3 Withdrawal state
0.635 0.365 0.000
D50-D53 Nutritional anaemias
0.635 0.365 0.000
O46.9 Antepartum haemorrhage, unspecified
0.634 0.366 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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