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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72952664
log Bayes Factor = 8.79899
Chromosome 2   position 216,969,624  (GRCh37) Explore rs72952664 on Ensembl!
Variant rs72952664 is part of Cluster X0240

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
R30-R39 Symptoms and signs involving the urinary system
0.997 0.003 0.000
I10-I15 Hypertensive diseases
0.997 0.003 0.000
Chapter V Mental and behavioural disorders
0.994 0.006 0.000
I60-I69 Cerebrovascular diseases
0.993 0.007 0.000
F30-F39 Mood [affective] disorders
0.986 0.014 0.000
I10 Essential (primary) hypertension
0.985 0.015 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.980 0.020 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.978 0.022 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.977 0.023 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.977 0.023 0.000
I69 Sequelae of cerebrovascular disease
0.973 0.027 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.970 0.030 0.000
Chapter XX External causes of morbidity and mortality
0.967 0.033 0.000
I12 Hypertensive renal disease
0.962 0.038 0.000
F31 Bipolar affective disorder
0.959 0.041 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.958 0.042 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.954 0.046 0.000
S20-S29 Injuries to the thorax
0.949 0.051 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.949 0.051 0.000
R32 Unspecified urinary incontinence
0.946 0.054 0.000
T40.2 Other opioids
0.946 0.054 0.000
R39 Other symptoms and signs involving the urinary system
0.942 0.058 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.941 0.059 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.934 0.066 0.000
I12.0 Hypertensive renal disease with renal failure
0.934 0.066 0.000
R33 Retention of urine
0.931 0.069 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.928 0.072 0.000
R39.1 Other difficulties with micturition
0.927 0.073 0.000
I05-I09 Chronic rheumatic heart diseases
0.922 0.078 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.921 0.079 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.920 0.080 0.000
S70-S79 Injuries to the hip and thigh
0.920 0.080 0.000
I63 Cerebral infarction
0.915 0.085 0.000
R35 Polyuria
0.912 0.088 0.000
R41.0 Disorientation, unspecified
0.905 0.095 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.902 0.098 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.897 0.103 0.000
T39.1 4-Aminophenol derivatives
0.895 0.105 0.000
I67 Other cerebrovascular diseases
0.889 0.111 0.000
R47-R49 Symptoms and signs involving speech and voice
0.889 0.111 0.000
T66-T78 Other and unspecified effects of external causes
0.883 0.117 0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.883 0.117 0.000
I95 Hypotension
0.880 0.120 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.875 0.124 0.000
R45 Symptoms and signs involving emotional state
0.873 0.127 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.872 0.128 0.000
F32 Depressive episode
0.863 0.137 0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.861 0.139 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.860 0.140 0.000
T39.0 Salicylates
0.859 0.141 0.000
S40-S49 Injuries to the shoulder and upper arm
0.854 0.146 0.000
R94 Abnormal results of function studies
0.850 0.150 0.000
T91 Sequelae of injuries of neck and trunk
0.848 0.152 0.000
Q23 Congenital malformations of aortic and mitral valves
0.847 0.153 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.847 0.153 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.846 0.154 0.000
R21 Rash and other nonspecific skin eruption
0.845 0.155 0.000
S27 Injury of other and unspecified intrathoracic organs
0.837 0.163 0.000
X60-X84 Intentional self-harm
0.834 0.166 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.832 0.168 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.832 0.168 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.831 0.169 0.000
F31.9 Bipolar affective disorder, unspecified
0.831 0.169 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.823 0.177 0.000
T90 Sequelae of injuries of head
0.818 0.182 0.000
I05 Rheumatic mitral valve diseases
0.816 0.184 0.000
I95.9 Hypotension, unspecified
0.814 0.186 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.813 0.187 0.000
S00-S09 Injuries to the head
0.812 0.188 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.811 0.189 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.810 0.190 0.000
Q50-Q56 Congenital malformations of genital organs
0.810 0.190 0.000
S90-S99 Injuries to the ankle and foot
0.809 0.191 0.000
T00-T07 Injuries involving multiple body regions
0.808 0.191 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.807 0.193 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.807 0.193 0.000
F39 Unspecified mood [affective] disorder
0.806 0.194 0.000
W50-W64 Exposure to animate mechanical forces
0.804 0.196 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.801 0.199 0.000
T40.4 Other synthetic narcotics
0.799 0.201 0.000
S80-S89 Injuries to the knee and lower leg
0.797 0.203 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.797 0.203 0.000
S10-S19 Injuries to the neck
0.797 0.203 0.000
R46 Symptoms and signs involving appearance and behaviour
0.796 0.204 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.796 0.204 0.000
T78 Adverse effects, not elsewhere classified
0.796 0.204 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.790 0.210 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.786 0.214 0.000
F33 Recurrent depressive disorder
0.784 0.216 0.000
Q21 Congenital malformations of cardiac septa
0.781 0.219 0.000
T31 Burns classified according to extent of body surface involved
0.781 0.219 0.000
F01 Vascular dementia
0.780 0.219 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.780 0.220 0.000
S00 Superficial injury of head
0.780 0.220 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.778 0.222 0.000
I95.1 Orthostatic hypotension
0.778 0.222 0.000
S22.4 Multiple fractures of ribs
0.778 0.222 0.000
V80-V89 Other land transport accidents
0.777 0.223 0.000
W20-W49 Exposure to inanimate mechanical forces
0.777 0.223 0.000
R20 Disturbances of skin sensation
0.776 0.224 0.000
Chapter XXII Codes for special purposes
0.773 0.227 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.772 0.228 0.000
F03 Unspecified dementia
0.772 0.228 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.769 0.231 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.768 0.232 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.767 0.233 0.000
R41.3 Other amnesia
0.766 0.234 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.765 0.235 0.000
T36 Poisoning by systemic antibiotics
0.764 0.236 0.000
I07 Rheumatic tricuspid valve diseases
0.762 0.238 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.762 0.238 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.761 0.239 0.000
T93 Sequelae of injuries of lower limb
0.759 0.241 0.000
T40.6 Other and unspecified narcotics
0.759 0.241 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.759 0.241 0.000
R47 Speech disturbances, not elsewhere classified
0.758 0.242 0.000
I67.2 Cerebral atherosclerosis
0.758 0.242 0.000
S72 Fracture of femur
0.758 0.242 0.000
T17 Foreign body in respiratory tract
0.756 0.244 0.000
Q23.1 Congenital insufficiency of aortic valve
0.756 0.244 0.000
V01-V09 Pedestrian injured in transport accident
0.755 0.245 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.755 0.245 0.000
Q60-Q64 Congenital malformations of the urinary system
0.753 0.247 0.000
S71 Open wound of hip and thigh
0.752 0.248 0.000
R34 Anuria and oliguria
0.751 0.249 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.751 0.249 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.749 0.251 0.000
Chapter I Certain infectious and parasitic diseases
0.748 0.252 0.000
F80-F89 Disorders of psychological development
0.746 0.254 0.000
S29 Other and unspecified injuries of thorax
0.746 0.254 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.746 0.254 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.745 0.254 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.740 0.260 0.000
I15 Secondary hypertension
0.739 0.261 0.000
X50-X57 Overexertion, travel and privation
0.739 0.261 0.000
S70 Superficial injury of hip and thigh
0.739 0.261 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.736 0.264 0.000
R49 Voice disturbances
0.735 0.265 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.732 0.268 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.732 0.268 0.000
S27.0 Traumatic pneumothorax
0.731 0.269 0.000
F32.9 Depressive episode, unspecified
0.730 0.270 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.729 0.271 0.000
S22.40 Multiple fractures of ribs (closed)
0.729 0.271 0.000
R94.5 Abnormal results of liver function studies
0.727 0.273 0.000
X20-X29 Contact with venomous animals and plants
0.722 0.278 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.722 0.278 0.000
T91.3 Sequelae of injury of spinal cord
0.721 0.279 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.721 0.279 0.000
S82 Fracture of lower leg, including ankle
0.721 0.279 0.000
S00.1 Contusion of eyelid and periocular area
0.719 0.281 0.000
X10-X19 Contact with heat and hot substances
0.719 0.281 0.000
R45.2 Unhappiness
0.719 0.281 0.000
T20 Burn and corrosion of head and neck
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.717 0.283 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.717 0.283 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.717 0.283 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.717 0.283 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
W00-W19 Falls
0.717 0.283 0.000
S79 Other and unspecified injuries of hip and thigh
0.716 0.284 0.000
T31.0 Burns involving less than 10% of body surface
0.716 0.284 0.000
R36 Urethral discharge
0.715 0.285 0.000
I63.9 Cerebral infarction, unspecified
0.715 0.285 0.000
I13 Hypertensive heart and renal disease
0.715 0.285 0.000
R45.8 Other symptoms and signs involving emotional state
0.714 0.286 0.000
I12.9 Hypertensive renal disease without renal failure
0.714 0.286 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.713 0.287 0.000
F70-F79 Mental retardation
0.713 0.287 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.712 0.288 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.712 0.288 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.712 0.288 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.711 0.289 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.711 0.289 0.000
Q80-Q89 Other congenital malformations
0.710 0.290 0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
0.710 0.290 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.708 0.292 0.000
F30 Manic episode
0.708 0.292 0.000
F38 Other mood [affective] disorders
0.707 0.293 0.000
F34 Persistent mood [affective] disorders
0.707 0.293 0.000
F05.9 Delirium, unspecified
0.706 0.294 0.000
I05.9 Mitral valve disease, unspecified
0.705 0.295 0.000
I67.1 Cerebral aneurysm, nonruptured
0.705 0.295 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.703 0.297 0.000
Q35-Q37 Cleft lip and cleft palate
0.703 0.297 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.703 0.297 0.000
I08 Multiple valve diseases
0.702 0.298 0.000
R43 Disturbances of smell and taste
0.701 0.299 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.701 0.299 0.000
T40.8 Lysergide [LSD]
0.701 0.299 0.000
T40.7 Cannabis (derivatives)
0.701 0.299 0.000
T40.5 Cocaine
0.701 0.299 0.000
T40.3 Methadone
0.701 0.299 0.000
T40.1 Heroin
0.701 0.299 0.000
T40.0 Opium
0.701 0.299 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.700 0.300 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.699 0.301 0.000
R47.8 Other and unspecified speech disturbances
0.699 0.301 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.698 0.302 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.698 0.302 0.000
Q27 Other congenital malformations of peripheral vascular system
0.696 0.304 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.696 0.304 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.696 0.304 0.000
T39.4 Antirheumatics, not elsewhere classified
0.696 0.304 0.000
T39.2 Pyrazolone derivatives
0.696 0.304 0.000
S00.9 Superficial injury of head, part unspecified
0.696 0.304 0.000
Q23.0 Congenital stenosis of aortic valve
0.695 0.305 0.000
S41 Open wound of shoulder and upper arm
0.694 0.306 0.000
I69.3 Sequelae of cerebral infarction
0.693 0.307 0.000
Y35-Y36 Legal intervention and operations of war
0.693 0.307 0.000
Y10-Y34 Event of undetermined intent
0.693 0.307 0.000
Y00-Y09 Assault
0.693 0.307 0.000
X85-X99 Assault
0.693 0.307 0.000
X30-X39 Exposure to forces of nature
0.693 0.307 0.000
X00-X09 Exposure to smoke, fire and flames
0.693 0.307 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.693 0.307 0.000
W75-W84 Other accidental threats to breathing
0.693 0.307 0.000
W65-W74 Accidental drowning and submersion
0.693 0.307 0.000
V98-V99 Other and unspecified transport accidents
0.693 0.307 0.000
V95-V97 Air and space transport accidents
0.693 0.307 0.000
V90-V94 Water transport accidents
0.693 0.307 0.000
V70-V79 Bus occupant injured in transport accident
0.693 0.307 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.693 0.307 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.693 0.307 0.000
V40-V49 Car occupant injured in transport accident
0.693 0.307 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.693 0.307 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.693 0.307 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.691 0.309 0.000
F60-F69 Disorders of adult personality and behaviour
0.691 0.309 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.691 0.309 0.000
S27.3 Other injuries of lung
0.690 0.310 0.000
R45.1 Restlessness and agitation
0.688 0.312 0.000
F31.8 Other bipolar affective disorders
0.687 0.313 0.000
F31.7 Bipolar affective disorder, currently in remission
0.687 0.313 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.687 0.313 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.687 0.313 0.000
T23 Burn and corrosion of wrist and hand
0.686 0.314 0.000
R44.3 Hallucinations, unspecified
0.685 0.315 0.000
T92 Sequelae of injuries of upper limb
0.684 0.316 0.000
R93.6 Abnormal findings on diagnostic imaging of limbs
0.684 0.316 0.000
R44.0 Auditory hallucinations
0.683 0.316 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.682 0.318 0.000
T17.2 Foreign body in pharynx
0.682 0.318 0.000
T42.4 Benzodiazepines
0.681 0.319 0.000
T91.8 Sequelae of other specified injuries of neck and trunk
0.681 0.319 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.680 0.319 0.000
S26 Injury of heart
0.680 0.319 0.000
S25 Injury of blood vessels of thorax
0.680 0.319 0.000
S24 Injury of nerves and spinal cord at thorax level
0.680 0.319 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.680 0.319 0.000
S21 Open wound of thorax
0.680 0.319 0.000
T95 Sequelae of burns, corrosions and frostbite
0.680 0.320 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.680 0.320 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.680 0.320 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.680 0.320 0.000
Q28 Other congenital malformations of circulatory system
0.680 0.320 0.000
B35-B49 Mycoses
0.680 0.320 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.679 0.321 0.000
R23 Other skin changes
0.678 0.322 0.000
T79-T79 Certain early complications of trauma
0.678 0.322 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.678 0.322 0.000
Q21.1 Atrial septal defect
0.676 0.324 0.000
R39.2 Extrarenal uraemia
0.675 0.325 0.000
R39.0 Extravasation of urine
0.675 0.325 0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
0.675 0.325 0.000
R41.1 Anterograde amnesia
0.675 0.325 0.000
S82.1 Fracture of upper end of tibia
0.675 0.325 0.000
Chapter VII Diseases of the eye and adnexa
0.674 0.326 0.000
F40 Phobic anxiety disorders
0.673 0.327 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.673 0.327 0.000
F01.9 Vascular dementia, unspecified
0.671 0.329 0.000
F32.0 Mild depressive episode
0.670 0.330 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.670 0.330 0.000
F02 Dementia in other diseases classified elsewhere
0.670 0.330 0.000
F09 Unspecified organic or symptomatic mental disorder
0.670 0.330 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.670 0.330 0.000
S49.9 Unspecified injury of shoulder and upper arm
0.668 0.332 0.000
W44 Foreign body entering into or through eye or natural orifice
0.668 0.332 0.000
R46.8 Other symptoms and signs involving appearance and behaviour
0.667 0.333 0.000
S72.0 Fracture of neck of femur
0.666 0.334 0.000
R94.4 Abnormal results of kidney function studies
0.666 0.334 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.665 0.335 0.000
Q26 Congenital malformations of great veins
0.665 0.335 0.000
Q25 Congenital malformations of great arteries
0.665 0.335 0.000
Q24 Other congenital malformations of heart
0.665 0.335 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.665 0.335 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.665 0.335 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.665 0.335 0.000
F99-F99 Unspecified mental disorder
0.664 0.335 0.000
R40 Somnolence, stupor and coma
0.664 0.336 0.000
I09 Other rheumatic heart diseases
0.661 0.339 0.000
I06 Rheumatic aortic valve diseases
0.661 0.339 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.660 0.340 0.000
S78 Traumatic amputation of hip and thigh
0.660 0.340 0.000
S77 Crushing injury of hip and thigh
0.660 0.340 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.660 0.340 0.000
S75 Injury of blood vessels at hip and thigh level
0.660 0.340 0.000
S74 Injury of nerves at hip and thigh level
0.660 0.340 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.660 0.340 0.000
T98 Sequelae of other and unspecified effects of external causes
0.659 0.341 0.000
Y43 Primarily systemic agents
0.659 0.341 0.000
T00 Superficial injuries involving multiple body regions
0.659 0.341 0.000
X62.9 Unspecified place
0.658 0.342 0.000
I99 Other and unspecified disorders of circulatory system
0.658 0.342 0.000
S22.2 Fracture of sternum
0.656 0.344 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.656 0.344 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.656 0.344 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.656 0.344 0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)
0.655 0.345 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.654 0.346 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.654 0.346 0.000
I95.8 Other hypotension
0.653 0.346 0.000
T91.1 Sequelae of fracture of spine
0.652 0.348 0.000
S99 Other and unspecified injuries of ankle and foot
0.652 0.348 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.651 0.349 0.000
T14 Injury of unspecified body region
0.650 0.350 0.000
S20 Superficial injury of thorax
0.649 0.351 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.649 0.351 0.000
T78.3 Angioneurotic oedema
0.648 0.352 0.000
I11 Hypertensive heart disease
0.648 0.352 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.647 0.352 0.000
I07.1 Tricuspid insufficiency
0.647 0.353 0.000
T50.8 Diagnostic agents
0.646 0.353 0.000
T50.7 Analeptics and opioid receptor antagonists
0.646 0.353 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.646 0.353 0.000
T50.5 Appetite depressants
0.646 0.353 0.000
T50.4 Drugs affecting uric acid metabolism
0.646 0.353 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.646 0.353 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.646 0.353 0.000
T50.1 Loop [high-ceiling] diuretics
0.646 0.353 0.000
T50.0 Mineralocorticoids and their antagonists
0.646 0.353 0.000
T68 Hypothermia
0.645 0.354 0.000
Q54 Hypospadias
0.644 0.356 0.000
W51 Striking against or bumped into by another person
0.644 0.356 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.643 0.357 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.643 0.357 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.643 0.357 0.000
T42.3 Barbiturates
0.643 0.357 0.000
T42.2 Succinimides and oxazolidinediones
0.643 0.357 0.000
T42.1 Iminostilbenes
0.643 0.357 0.000
T42.0 Hydantoin derivatives
0.643 0.357 0.000
R44.1 Visual hallucinations
0.643 0.357 0.000
S40 Superficial injury of shoulder and upper arm
0.642 0.357 0.000
Chapter VI Diseases of the nervous system
0.642 0.358 0.000
S82.10 Fracture of upper end of tibia (closed)
0.642 0.358 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.642 0.358 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.641 0.359 0.000
T78.2 Anaphylactic shock, unspecified
0.641 0.359 0.000
R90.0 Intracranial space-occupying lesion
0.640 0.359 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.640 0.360 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.639 0.361 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.638 0.362 0.000
I67.8 Other specified cerebrovascular diseases
0.638 0.362 0.000
Q00-Q07 Congenital malformations of the nervous system
0.638 0.362 0.000
Y45.1 Salicylates
0.638 0.362 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.637 0.363 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.637 0.363 0.000
I67.5 Moyamoya disease
0.637 0.363 0.000
I67.4 Hypertensive encephalopathy
0.637 0.363 0.000
I67.3 Progressive vascular leukoencephalopathy
0.637 0.363 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.637 0.363 0.000
S06 Intracranial injury
0.637 0.363 0.000
T56 Toxic effect of metals
0.636 0.364 0.000
R30 Pain associated with micturition
0.636 0.364 0.000
F00 Dementia in Alzheimer's disease
0.635 0.364 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.635 0.365 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.634 0.366 0.000
T75 Effects of other external causes
0.633 0.366 0.000
T74 Maltreatment syndromes
0.633 0.366 0.000
T73 Effects of other deprivation
0.633 0.366 0.000
T70 Effects of air pressure and water pressure
0.633 0.366 0.000
T69 Other effects of reduced temperature
0.633 0.366 0.000
T67 Effects of heat and light
0.633 0.366 0.000
T71 Asphyxiation
0.633 0.366 0.000
T66 Unspecified effects of radiation
0.633 0.366 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.633 0.367 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.633 0.367 0.000
S71.1 Open wound of thigh
0.631 0.368 0.000
I95.0 Idiopathic hypotension
0.631 0.369 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.631 0.369 0.000
T78.0 Anaphylactic shock due to adverse food reaction
0.630 0.369 0.000
V20-V29 Motorcycle rider injured in transport accident
0.629 0.370 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.629 0.371 0.000
I05.0 Mitral stenosis
0.629 0.371 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.628 0.372 0.000
T25 Burn and corrosion of ankle and foot
0.628 0.372 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.628 0.372 0.000
T21 Burn and corrosion of trunk
0.628 0.372 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.628 0.372 0.000
R45.7 State of emotional shock and stress, unspecified
0.626 0.374 0.000
R45.6 Physical violence
0.626 0.374 0.000
R45.5 Hostility
0.626 0.374 0.000
R45.4 Irritability and anger
0.626 0.374 0.000
R45.3 Demoralisation and apathy
0.626 0.374 0.000
R45.0 Nervousness
0.626 0.374 0.000
S86 Injury of muscle and tendon at lower leg level
0.626 0.374 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.626 0.374 0.000
R41.2 Retrograde amnesia
0.626 0.374 0.000
T32 Corrosions classified according to extent of body surface involved
0.625 0.374 0.000
T30 Burn and corrosion, body region unspecified
0.625 0.374 0.000
T29 Burns and corrosions of multiple body regions
0.625 0.374 0.000
T18 Foreign body in alimentary tract
0.625 0.375 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.624 0.376 0.000
I60 Subarachnoid haemorrhage
0.623 0.377 0.000
V10-V19 Pedal cyclist injured in transport accident
0.621 0.379 0.000
I05.2 Mitral stenosis with insufficiency
0.620 0.380 0.000
F32.8 Other depressive episodes
0.619 0.381 0.000
S19 Other and unspecified injuries of neck
0.617 0.383 0.000
I61 Intracerebral haemorrhage
0.617 0.383 0.000
S70.9 Superficial injury of hip and thigh, unspecified
0.617 0.383 0.000
T19 Foreign body in genito-urinary tract
0.616 0.383 0.000
T15 Foreign body on external eye
0.616 0.383 0.000
T16 Foreign body in ear
0.616 0.383 0.000
R94.3 Abnormal results of cardiovascular function studies
0.615 0.385 0.000
X58 Exposure to other specified factors
0.615 0.385 0.000
T93.2 Sequelae of other fractures of lower limb
0.614 0.386 0.000
A30-A49 Other bacterial diseases
0.613 0.387 0.000
S12 Fracture of neck
0.613 0.387 0.000
S48 Traumatic amputation of shoulder and upper arm
0.612 0.388 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.612 0.388 0.000
S44 Injury of nerves at shoulder and upper arm level
0.612 0.388 0.000
S47 Crushing injury of shoulder and upper arm
0.612 0.388 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.612 0.388 0.000
R20.2 Paraesthesia of skin
0.610 0.390 0.000
W55 Bitten or struck by other mammals
0.610 0.390 0.000
R94.8 Abnormal results of function studies of other organs and systems
0.609 0.391 0.000
R94.7 Abnormal results of other endocrine function studies
0.609 0.391 0.000
R94.6 Abnormal results of thyroid function studies
0.609 0.391 0.000
R94.2 Abnormal results of pulmonary function studies
0.609 0.391 0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses
0.609 0.391 0.000
R94.0 Abnormal results of function studies of central nervous system
0.609 0.391 0.000
T90.4 Sequelae of injury of eye and orbit
0.609 0.391 0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person
0.609 0.391 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.608 0.392 0.000
T91.9 Sequelae of unspecified injury of neck and trunk
0.608 0.392 0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs
0.608 0.392 0.000
T91.4 Sequelae of injury of intrathoracic organs
0.608 0.392 0.000
T91.2 Sequelae of other fracture of thorax and pelvis
0.608 0.392 0.000
T91.0 Sequelae of superficial injury and open wound of neck and trunk
0.608 0.392 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.608 0.392 0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified
0.607 0.392 0.000
Q23.8 Other congenital malformations of aortic and mitral valves
0.607 0.392 0.000
Q23.4 Hypoplastic left heart syndrome
0.607 0.392 0.000
Q23.3 Congenital mitral insufficiency
0.607 0.392 0.000
Q23.2 Congenital mitral stenosis
0.607 0.392 0.000
T58 Toxic effect of carbon monoxide
0.607 0.392 0.000
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions
0.607 0.393 0.000
R44.2 Other hallucinations
0.607 0.393 0.000
S22.9 Fracture of bony thorax, part unspecified
0.607 0.393 0.000
S22.8 Fracture of other parts of bony thorax
0.607 0.393 0.000
S22.5 Flail chest
0.607 0.393 0.000
S22.1 Multiple fractures of thoracic spine
0.606 0.394 0.000
Y54.3 Benzothiadiazine derivatives
0.606 0.394 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.604 0.396 0.000
V01 Pedestrian injured in collision with pedal cycle
0.604 0.396 0.000
R47.0 Dysphasia and aphasia
0.604 0.396 0.000
T20.1 Burn of first degree of head and neck
0.604 0.396 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.604 0.396 0.000
Q43 Other congenital malformations of intestine
0.602 0.398 0.000
S90 Superficial injury of ankle and foot
0.601 0.398 0.000
F42 Obsessive-compulsive disorder
0.601 0.399 0.000
S72.00 Fracture of neck of femur (closed)
0.601 0.399 0.000
S27.9 Injury of unspecified intrathoracic organ
0.600 0.400 0.000
S27.8 Injury of other specified intrathoracic organs
0.600 0.400 0.000
S27.7 Multiple injuries of intrathoracic organs
0.600 0.400 0.000
S27.6 Injury of pleura
0.600 0.400 0.000
S27.5 Injury of thoracic trachea
0.600 0.400 0.000
S27.4 Injury of bronchus
0.600 0.400 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.600 0.400 0.000
S29.9 Unspecified injury of thorax
0.600 0.400 0.000
H55-H59 Other disorders of eye and adnexa
0.599 0.400 0.000
T02 Fractures involving multiple body regions
0.599 0.401 0.000
X84 Intentional self-harm by unspecified means
0.598 0.402 0.000
X83 Intentional self-harm by other specified means
0.598 0.402 0.000
X82 Intentional self-harm by crashing of motor vehicle
0.598 0.402 0.000
X81 Intentional self-harm by jumping or lying before moving object
0.598 0.402 0.000
X80 Intentional self-harm by jumping from a high place
0.598 0.402 0.000
X79 Intentional self-harm by blunt object
0.598 0.402 0.000
X77 Intentional self-harm by steam, hot vapours and hot objects
0.598 0.402 0.000
X76 Intentional self-harm by smoke, fire and flames
0.598 0.402 0.000
X75 Intentional self-harm by explosive material
0.598 0.402 0.000
X74 Intentional self-harm by other and unspecified firearm discharge
0.598 0.402 0.000
X73 Intentional self-harm by rifle, shotgun and larger firearm discharge
0.598 0.402 0.000
X72 Intentional self-harm by handgun discharge
0.598 0.402 0.000
X71 Intentional self-harm by drowning and submersion
0.598 0.402 0.000
X70 Intentional self-harm by hanging, strangulation and suffocation
0.598 0.402 0.000
X69 Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
0.598 0.402 0.000
X68 Intentional self-poisoning by and exposure to pesticides
0.598 0.402 0.000
X67 Intentional self-poisoning by and exposure to other gases and vapours
0.598 0.402 0.000
X66 Intentional self-poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours
0.598 0.402 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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