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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7309269
log Bayes Factor = 13.6679
Chromosome 12   position 7,757,834  (GRCh37) Explore rs7309269 on Ensembl!
Variant rs7309269 is part of Cluster X0123

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter XX External causes of morbidity and mortality
0.998 0.002 0.000
J40-J47 Chronic lower respiratory diseases
0.998 0.002 0.000
G40-G47 Episodic and paroxysmal disorders
0.998 0.002 0.000
G40 Epilepsy
0.992 0.008 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.992 0.008 0.000
J09-J18 Influenza and pneumonia
0.987 0.013 0.000
J44 Other chronic obstructive pulmonary disease
0.987 0.013 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.982 0.018 0.000
S00-S09 Injuries to the head
0.982 0.018 0.000
M50-M54 Other dorsopathies
0.978 0.022 0.000
J18 Pneumonia, organism unspecified
0.977 0.023 0.000
R47-R49 Symptoms and signs involving speech and voice
0.977 0.023 0.000
S00 Superficial injury of head
0.972 0.028 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.968 0.032 0.000
J18.9 Pneumonia, unspecified
0.962 0.038 0.000
S20-S29 Injuries to the thorax
0.961 0.039 0.000
W00-W19 Falls
0.959 0.041 0.000
G43 Migraine
0.955 0.045 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.955 0.045 0.000
M05-M14 Inflammatory polyarthropathies
0.951 0.049 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.950 0.050 0.000
M45-M49 Spondylopathies
0.950 0.050 0.000
G30-G32 Other degenerative diseases of the nervous system
0.948 0.052 0.000
S00.8 Superficial injury of other parts of head
0.935 0.065 0.000
R49 Voice disturbances
0.934 0.066 0.000
Chapter I Certain infectious and parasitic diseases
0.933 0.067 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.932 0.068 0.000
M86-M90 Other osteopathies
0.926 0.074 0.000
M51 Other intervertebral disk disorders
0.924 0.076 0.000
M06 Other rheumatoid arthritis
0.923 0.077 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.923 0.077 0.000
M48 Other spondylopathies
0.922 0.078 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.921 0.078 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.920 0.080 0.000
G82 Paraplegia and tetraplegia
0.918 0.082 0.000
J47 Bronchiectasis
0.913 0.087 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.910 0.090 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.909 0.091 0.000
R47 Speech disturbances, not elsewhere classified
0.908 0.092 0.000
M06.9 Rheumatoid arthritis, unspecified
0.908 0.092 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.905 0.095 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.902 0.098 0.000
S01 Open wound of head
0.900 0.100 0.000
W19 Unspecified fall
0.897 0.103 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.894 0.106 0.000
R49.0 Dysphonia
0.893 0.107 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.890 0.110 0.000
G43.9 Migraine, unspecified
0.889 0.111 0.000
Chapter XXII Codes for special purposes
0.887 0.113 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.886 0.114 0.000
V10-V19 Pedal cyclist injured in transport accident
0.883 0.117 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.881 0.119 0.000
R29.6 Tendency to fall, not elsewhere classified
0.878 0.122 0.000
G40.9 Epilepsy, unspecified
0.876 0.124 0.000
M48.0 Spinal stenosis
0.875 0.125 0.000
Chapter II Neoplasms
0.871 0.129 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.871 0.129 0.000
M51.2 Other specified intervertebral disk displacement
0.871 0.129 0.000
W19.9 Unspecified place
0.870 0.130 0.000
J42 Unspecified chronic bronchitis
0.869 0.131 0.000
J46 Status asthmaticus
0.868 0.132 0.000
J00-J06 Acute upper respiratory infections
0.866 0.134 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.862 0.138 0.000
M20-M25 Other joint disorders
0.859 0.141 0.000
Chapter VIII Diseases of the ear and mastoid process
0.859 0.141 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.858 0.142 0.000
M48.06 Spinal stenosis (Lumbar region)
0.858 0.142 0.000
M54 Dorsalgia
0.856 0.144 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.855 0.145 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.853 0.147 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.853 0.147 0.000
Y52 Agents primarily affecting the cardiovascular system
0.851 0.149 0.000
W20-W49 Exposure to inanimate mechanical forces
0.850 0.150 0.000
Y40 Systemic antibiotics
0.847 0.153 0.000
G82.2 Paraplegia, unspecified
0.846 0.154 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.844 0.156 0.000
M80-M85 Disorders of bone density and structure
0.842 0.158 0.000
G70-G73 Diseases of myoneural junction and muscle
0.841 0.159 0.000
J18.1 Lobar pneumonia, unspecified
0.838 0.162 0.000
R47.8 Other and unspecified speech disturbances
0.835 0.165 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.834 0.166 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.832 0.168 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.829 0.171 0.000
M50 Cervical disk disorders
0.827 0.173 0.000
Y43 Primarily systemic agents
0.822 0.178 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.821 0.179 0.000
H80-H83 Diseases of inner ear
0.818 0.182 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.814 0.186 0.000
S22.0 Fracture of thoracic vertebra
0.814 0.186 0.000
R00 Abnormalities of heart beat
0.812 0.188 0.000
M24 Other specific joint derangements
0.810 0.190 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.805 0.195 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.804 0.196 0.000
G44 Other headache syndromes
0.804 0.196 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.803 0.197 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.800 0.200 0.000
S22.4 Multiple fractures of ribs
0.800 0.200 0.000
M54.1 Radiculopathy
0.799 0.200 0.000
J43 Emphysema
0.798 0.202 0.000
M25 Other joint disorders, not elsewhere classified
0.797 0.203 0.000
G82.5 Tetraplegia, unspecified
0.797 0.203 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.796 0.204 0.000
G43.1 Migraine with aura [classical migraine]
0.794 0.206 0.000
R47.0 Dysphasia and aphasia
0.792 0.208 0.000
B25-B34 Other viral diseases
0.792 0.208 0.000
M87 Osteonecrosis
0.790 0.210 0.000
S10-S19 Injuries to the neck
0.790 0.210 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.790 0.210 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.789 0.211 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.789 0.211 0.000
M45 Ankylosing spondylitis
0.787 0.213 0.000
V80-V89 Other land transport accidents
0.785 0.215 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.785 0.215 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.784 0.216 0.000
S00.9 Superficial injury of head, part unspecified
0.784 0.216 0.000
C64-C68 Malignant neoplasms of urinary tract
0.783 0.217 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.783 0.217 0.000
M40-M43 Deforming dorsopathies
0.782 0.218 0.000
S00.0 Superficial injury of scalp
0.781 0.219 0.000
M86 Osteomyelitis
0.781 0.219 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.780 0.220 0.000
R05 Cough
0.779 0.221 0.000
W17 Other fall from one level to another
0.778 0.222 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.778 0.222 0.000
Q50-Q56 Congenital malformations of genital organs
0.777 0.223 0.000
T92 Sequelae of injuries of upper limb
0.777 0.223 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.775 0.225 0.000
T91 Sequelae of injuries of neck and trunk
0.775 0.225 0.000
M10 Gout
0.774 0.226 0.000
Q00-Q07 Congenital malformations of the nervous system
0.773 0.226 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.773 0.227 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.773 0.227 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.772 0.228 0.000
G90-G99 Other disorders of the nervous system
0.770 0.230 0.000
G35 Multiple sclerosis
0.770 0.230 0.000
S27 Injury of other and unspecified intrathoracic organs
0.769 0.231 0.000
Q80-Q89 Other congenital malformations
0.767 0.232 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.767 0.233 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.765 0.235 0.000
T93 Sequelae of injuries of lower limb
0.765 0.235 0.000
S00.1 Contusion of eyelid and periocular area
0.765 0.235 0.000
Y48 Anaesthetics and therapeutic gases
0.764 0.236 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.764 0.236 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.764 0.236 0.000
R00.1 Bradycardia, unspecified
0.762 0.238 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.762 0.238 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.762 0.238 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.761 0.239 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.761 0.239 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.761 0.239 0.000
S01.4 Open wound of cheek and temporomandibular area
0.758 0.242 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.758 0.242 0.000
S40-S49 Injuries to the shoulder and upper arm
0.757 0.242 0.000
G40.8 Other epilepsy
0.756 0.244 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.756 0.244 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.755 0.245 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.754 0.246 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.753 0.246 0.000
S29 Other and unspecified injuries of thorax
0.753 0.247 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.752 0.248 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.752 0.248 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.749 0.251 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.749 0.251 0.000
G61 Inflammatory polyneuropathy
0.748 0.252 0.000
G43.8 Other migraine
0.748 0.252 0.000
M89 Other disorders of bone
0.748 0.252 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.747 0.253 0.000
M60-M63 Disorders of muscles
0.747 0.253 0.000
S01.5 Open wound of lip and oral cavity
0.747 0.253 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.746 0.253 0.000
Q23 Congenital malformations of aortic and mitral valves
0.746 0.254 0.000
C67 Malignant neoplasm of bladder
0.746 0.254 0.000
J90-J94 Other diseases of pleura
0.746 0.254 0.000
S01.0 Open wound of scalp
0.746 0.254 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.745 0.255 0.000
S22.00 Fracture of thoracic vertebra (closed)
0.745 0.255 0.000
S90-S99 Injuries to the ankle and foot
0.744 0.256 0.000
R20 Disturbances of skin sensation
0.743 0.257 0.000
W13 Fall from, out of or through building or structure
0.742 0.258 0.000
G82.1 Spastic paraplegia
0.741 0.259 0.000
M91-M94 Chondropathies
0.740 0.260 0.000
G31.8 Other specified degenerative diseases of nervous system
0.739 0.261 0.000
M50.3 Other cervical disk degeneration
0.739 0.261 0.000
X20-X29 Contact with venomous animals and plants
0.738 0.262 0.000
R50-R69 General symptoms and signs
0.738 0.262 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.735 0.265 0.000
R49.8 Other and unspecified voice disturbances
0.735 0.265 0.000
S22.1 Multiple fractures of thoracic spine
0.735 0.265 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.732 0.268 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.732 0.268 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.731 0.269 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.730 0.270 0.000
T79-T79 Certain early complications of trauma
0.729 0.271 0.000
M25.5 Pain in joint
0.729 0.271 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.728 0.272 0.000
S01.8 Open wound of other parts of head
0.727 0.273 0.000
D47.2 Monoclonal gammopathy
0.727 0.273 0.000
B99-B99 Other infectious diseases
0.726 0.274 0.000
M21 Other acquired deformities of limbs
0.725 0.275 0.000
V18.0 Driver injured in nontraffic accident
0.723 0.277 0.000
J11 Influenza, virus not identified
0.723 0.277 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.723 0.277 0.000
M00-M03 Infectious arthropathies
0.723 0.277 0.000
M11 Other crystal arthropathies
0.722 0.277 0.000
V40-V49 Car occupant injured in transport accident
0.721 0.279 0.000
S22.40 Multiple fractures of ribs (closed)
0.721 0.279 0.000
H90-H95 Other disorders of ear
0.720 0.280 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.720 0.280 0.000
J18.0 Bronchopneumonia, unspecified
0.719 0.281 0.000
R00.0 Tachycardia, unspecified
0.719 0.281 0.000
H83 Other diseases of inner ear
0.718 0.282 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.716 0.284 0.000
Y35-Y36 Legal intervention and operations of war
0.716 0.284 0.000
Y10-Y34 Event of undetermined intent
0.716 0.284 0.000
Y00-Y09 Assault
0.716 0.284 0.000
X85-X99 Assault
0.716 0.284 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.716 0.284 0.000
X50-X57 Overexertion, travel and privation
0.716 0.284 0.000
X30-X39 Exposure to forces of nature
0.716 0.284 0.000
X10-X19 Contact with heat and hot substances
0.716 0.284 0.000
X00-X09 Exposure to smoke, fire and flames
0.716 0.284 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.716 0.284 0.000
W75-W84 Other accidental threats to breathing
0.716 0.284 0.000
W65-W74 Accidental drowning and submersion
0.716 0.284 0.000
W50-W64 Exposure to animate mechanical forces
0.716 0.284 0.000
V98-V99 Other and unspecified transport accidents
0.716 0.284 0.000
V95-V97 Air and space transport accidents
0.716 0.284 0.000
V90-V94 Water transport accidents
0.716 0.284 0.000
V70-V79 Bus occupant injured in transport accident
0.716 0.284 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.716 0.284 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.716 0.284 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.716 0.284 0.000
V01-V09 Pedestrian injured in transport accident
0.716 0.284 0.000
J41 Simple and mucopurulent chronic bronchitis
0.716 0.284 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.715 0.284 0.000
U88 Agent resistant to multiple antibiotics
0.716 0.284 0.000
V20-V29 Motorcycle rider injured in transport accident
0.715 0.285 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.714 0.285 0.000
Y40.8 Other systemic antibiotics
0.714 0.286 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.713 0.287 0.000
B02 Zoster [herpes zoster]
0.713 0.287 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.711 0.289 0.000
G40.5 Special epileptic syndromes
0.711 0.289 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.711 0.289 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.711 0.289 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.711 0.289 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.710 0.290 0.000
G41 Status epilepticus
0.710 0.290 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.709 0.291 0.000
G37 Other demyelinating diseases of central nervous system
0.708 0.292 0.000
J17 Pneumonia in diseases classified elsewhere
0.708 0.292 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.708 0.292 0.000
J12 Viral pneumonia, not elsewhere classified
0.708 0.292 0.000
J09 Influenza due to certain identified influenza virus
0.708 0.292 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.708 0.292 0.000
J60-J70 Lung diseases due to external agents
0.708 0.292 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.706 0.294 0.000
Y95 Nosocomial condition
0.706 0.294 0.000
Q60-Q64 Congenital malformations of the urinary system
0.706 0.294 0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)
0.704 0.296 0.000
Y59 Other and unspecified vaccines and biological substances
0.704 0.296 0.000
Y58 Bacterial vaccines
0.704 0.296 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.704 0.296 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.704 0.296 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.704 0.296 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.704 0.296 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.704 0.296 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.704 0.296 0.000
B95-B98 Bacterial, viral and other infectious agents
0.704 0.296 0.000
S08 Traumatic amputation of part of head
0.704 0.296 0.000
S07 Crushing injury of head
0.704 0.296 0.000
S04 Injury of cranial nerves
0.704 0.296 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.704 0.296 0.000
B15-B19 Viral hepatitis
0.703 0.296 0.000
M54.12 Radiculopathy (Cervical region)
0.703 0.297 0.000
Y43.3 Other antineoplastic drugs
0.702 0.298 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.701 0.299 0.000
J18.8 Other pneumonia, organism unspecified
0.701 0.299 0.000
J18.2 Hypostatic pneumonia, unspecified
0.701 0.299 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.700 0.299 0.000
H80 Otosclerosis
0.700 0.300 0.000
G83 Other paralytic syndromes
0.698 0.302 0.000
S00.7 Multiple superficial injuries of head
0.697 0.303 0.000
S00.5 Superficial injury of lip and oral cavity
0.697 0.303 0.000
S00.4 Superficial injury of ear
0.697 0.303 0.000
S00.3 Superficial injury of nose
0.697 0.303 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.697 0.303 0.000
A30-A49 Other bacterial diseases
0.696 0.304 0.000
G31.2 Degeneration of nervous system due to alcohol
0.696 0.304 0.000
B00 Herpesviral [herpes simplex] infections
0.695 0.305 0.000
W22 Striking against or struck by other objects
0.695 0.305 0.000
J10 Influenza due to identified influenza virus
0.695 0.305 0.000
W29 Contact with other powered hand tools and household machinery
0.695 0.305 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.694 0.306 0.000
Q35-Q37 Cleft lip and cleft palate
0.694 0.306 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.694 0.306 0.000
S20 Superficial injury of thorax
0.694 0.306 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.694 0.306 0.000
T66-T78 Other and unspecified effects of external causes
0.692 0.308 0.000
B35-B49 Mycoses
0.692 0.308 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.691 0.309 0.000
Chapter IX Diseases of the circulatory system
0.691 0.309 0.000
M24.1 Other articular cartilage disorders
0.690 0.310 0.000
B07 Viral warts
0.690 0.310 0.000
R20.2 Paraesthesia of skin
0.689 0.311 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.689 0.311 0.000
S26 Injury of heart
0.689 0.311 0.000
S25 Injury of blood vessels of thorax
0.689 0.311 0.000
S24 Injury of nerves and spinal cord at thorax level
0.689 0.311 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.689 0.311 0.000
S21 Open wound of thorax
0.689 0.311 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.688 0.312 0.000
S70-S79 Injuries to the hip and thigh
0.688 0.312 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.687 0.312 0.000
W15 Fall from cliff
0.687 0.312 0.000
W14 Fall from tree
0.687 0.312 0.000
W12 Fall on and from scaffolding
0.687 0.312 0.000
W11 Fall on and from ladder
0.687 0.312 0.000
W09 Fall involving playground equipment
0.687 0.312 0.000
W05 Fall involving wheelchair
0.687 0.312 0.000
W04 Fall while being carried or supported by other persons
0.687 0.312 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.687 0.312 0.000
W00 Fall on same level involving ice and snow
0.687 0.312 0.000
H81 Disorders of vestibular function
0.688 0.312 0.000
J04 Acute laryngitis and tracheitis
0.687 0.313 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.687 0.313 0.000
G60 Hereditary and idiopathic neuropathy
0.686 0.314 0.000
G43.3 Complicated migraine
0.685 0.315 0.000
G43.2 Status migrainosus
0.685 0.315 0.000
G43.0 Migraine without aura [common migraine]
0.685 0.315 0.000
M07 Psoriatic and enteropathic arthropathies
0.685 0.315 0.000
S05 Injury of eye and orbit
0.685 0.315 0.000
M54.3 Sciatica
0.684 0.316 0.000
W18 Other fall on same level
0.683 0.317 0.000
C78.7 Secondary malignant neoplasm of liver
0.683 0.317 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.683 0.317 0.000
R53 Malaise and fatigue
0.682 0.318 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.682 0.318 0.000
M54.2 Cervicalgia
0.682 0.318 0.000
M14 Arthropathies in other diseases classified elsewhere
0.682 0.318 0.000
M12 Other specific arthropathies
0.682 0.318 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.682 0.318 0.000
M08 Juvenile arthritis
0.682 0.318 0.000
M54.9 Dorsalgia, unspecified
0.682 0.318 0.000
W19.4 Street and highway
0.681 0.319 0.000
M49 Spondylopathies in diseases classified elsewhere
0.681 0.319 0.000
M06.4 Inflammatory polyarthropathy
0.681 0.319 0.000
G71 Primary disorders of muscles
0.680 0.320 0.000
C67.2 Lateral wall of bladder
0.680 0.320 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.680 0.320 0.000
B34 Viral infection of unspecified site
0.679 0.321 0.000
W08 Fall involving other furniture
0.679 0.321 0.000
S01.7 Multiple open wounds of head
0.678 0.322 0.000
Y40.0 Penicillins
0.678 0.322 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.677 0.323 0.000
M86.9 Osteomyelitis, unspecified
0.677 0.323 0.000
Y57 Other and unspecified drugs and medicaments
0.676 0.324 0.000
Q43 Other congenital malformations of intestine
0.675 0.325 0.000
M87.9 Osteonecrosis, unspecified
0.675 0.325 0.000
S01.2 Open wound of nose
0.675 0.325 0.000
R21 Rash and other nonspecific skin eruption
0.675 0.325 0.000
M25.51 Pain in joint (Shoulder region)
0.675 0.325 0.000
Y44 Agents primarily affecting blood constituents
0.674 0.326 0.000
G70 Myasthenia gravis and other myoneural disorders
0.674 0.326 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.674 0.326 0.000
M96.8 Other postprocedural musculoskeletal disorders
0.673 0.326 0.000
M46 Other inflammatory spondylopathies
0.673 0.327 0.000
G20-G26 Extrapyramidal and movement disorders
0.671 0.329 0.000
M82 Osteoporosis in diseases classified elsewhere
0.671 0.329 0.000
G06.1 Intraspinal abscess and granuloma
0.670 0.329 0.000
M65-M68 Disorders of synovium and tendon
0.670 0.330 0.000
R49.2 Hypernasality and hyponasality
0.669 0.330 0.000
R49.1 Aphonia
0.669 0.330 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.669 0.331 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.669 0.331 0.000
B65-B83 Helminthiases
0.669 0.331 0.000
B50-B64 Protozoal diseases
0.669 0.331 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.669 0.331 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.669 0.331 0.000
A75-A79 Rickettsioses
0.669 0.331 0.000
A70-A74 Other diseases caused by chlamydiae
0.669 0.331 0.000
A65-A69 Other spirochaetal diseases
0.669 0.331 0.000
A20-A28 Certain zoonotic bacterial diseases
0.669 0.331 0.000
A15-A19 Tuberculosis
0.669 0.331 0.000
R02 Gangrene, not elsewhere classified
0.669 0.331 0.000
Q23.1 Congenital insufficiency of aortic valve
0.668 0.332 0.000
S01.3 Open wound of ear
0.668 0.332 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.668 0.332 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.668 0.332 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.668 0.332 0.000
M51.8 Other specified intervertebral disk disorders
0.667 0.333 0.000
M33 Dermatopolymyositis
0.666 0.334 0.000
G80 Infantile cerebral palsy
0.665 0.335 0.000
M85 Other disorders of bone density and structure
0.665 0.335 0.000
J14 Pneumonia due to Haemophilus influenzae
0.665 0.335 0.000
M90 Osteopathies in diseases classified elsewhere
0.664 0.336 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.663 0.337 0.000
Q24 Other congenital malformations of heart
0.663 0.337 0.000
J06.9 Acute upper respiratory infection, unspecified
0.662 0.338 0.000
M51.3 Other specified intervertebral disk degeneration
0.662 0.338 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.662 0.338 0.000
M51.4 Schmorl's nodes
0.662 0.338 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.662 0.338 0.000
M06.8 Other specified rheumatoid arthritis
0.662 0.338 0.000
M06.3 Rheumatoid nodule
0.662 0.338 0.000
M06.2 Rheumatoid bursitis
0.662 0.338 0.000
M06.1 Adult-onset Still's disease
0.662 0.338 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.662 0.338 0.000
M48.9 Spondylopathy, unspecified
0.661 0.339 0.000
M48.8 Other specified spondylopathies
0.661 0.339 0.000
M48.4 Fatigue fracture of vertebra
0.661 0.339 0.000
M48.3 Traumatic spondylopathy
0.661 0.339 0.000
M48.2 Kissing spine
0.661 0.339 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.661 0.339 0.000
W21 Striking against or struck by sports equipment
0.661 0.339 0.000
G31.1 Senile degeneration of brain, not elsewhere classified
0.661 0.339 0.000
G31.0 Circumscribed brain atrophy
0.661 0.339 0.000
T98 Sequelae of other and unspecified effects of external causes
0.660 0.340 0.000
T95 Sequelae of burns, corrosions and frostbite
0.660 0.340 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.660 0.340 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.660 0.340 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.660 0.340 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.659 0.341 0.000
W01.6 Industrial and construction area
0.659 0.341 0.000
G82.4 Spastic tetraplegia
0.658 0.342 0.000
G82.3 Flaccid tetraplegia
0.658 0.342 0.000
G82.0 Flaccid paraplegia
0.658 0.342 0.000
R23 Other skin changes
0.658 0.342 0.000
M30 Polyarteritis nodosa and related conditions
0.656 0.344 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.656 0.344 0.000
R22.4 Localised swelling, mass and lump, lower limb
0.656 0.344 0.000
W06 Fall involving bed
0.655 0.344 0.000
M54.17 Radiculopathy (Lumbosacral region)
0.655 0.345 0.000
G61.0 Guillain-Barre syndrome
0.654 0.346 0.000
W19.3 Sports and athletics area
0.654 0.346 0.000
M88 Paget's disease of bone [osteitis deformans]
0.654 0.346 0.000
M25.3 Other instability of joint
0.654 0.346 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.653 0.347 0.000
S22.9 Fracture of bony thorax, part unspecified
0.652 0.348 0.000
S22.8 Fracture of other parts of bony thorax
0.652 0.348 0.000
S22.5 Flail chest
0.652 0.348 0.000
G62 Other polyneuropathies
0.652 0.348 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.651 0.348 0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)
0.651 0.348 0.000
R29.4 Clicking hip
0.651 0.348 0.000
R29.3 Abnormal posture
0.651 0.348 0.000
R29.2 Abnormal reflex
0.651 0.348 0.000
R29.1 Meningismus
0.651 0.348 0.000
R29.0 Tetany
0.651 0.348 0.000
J01 Acute sinusitis
0.651 0.349 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.651 0.349 0.000
J95-J99 Other diseases of the respiratory system
0.651 0.349 0.000
R27 Other lack of coordination
0.650 0.349 0.000
M89.0 Algoneurodystrophy
0.650 0.349 0.000
M53 Other dorsopathies, not elsewhere classified
0.650 0.350 0.000
M05 Seropositive rheumatoid arthritis
0.650 0.350 0.000
M50.1 Cervical disk disorder with radiculopathy
0.649 0.351 0.000
W17.4 Street and highway
0.649 0.351 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.649 0.351 0.000
G81 Hemiplegia
0.648 0.352 0.000
W07 Fall involving chair
0.648 0.352 0.000
M10.9 Gout, unspecified
0.648 0.352 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.647 0.353 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.647 0.353 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.647 0.353 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.647 0.353 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.647 0.353 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.647 0.353 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.647 0.353 0.000
T36 Poisoning by systemic antibiotics
0.647 0.353 0.000
X60-X84 Intentional self-harm
0.647 0.353 0.000
H83.0 Labyrinthitis
0.647 0.353 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.647 0.353 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.644 0.356 0.000
Y43.1 Antineoplastic antimetabolites
0.644 0.356 0.000
G03 Meningitis due to other and unspecified causes
0.644 0.356 0.000
M84 Disorders of continuity of bone
0.644 0.356 0.000
W19.8 Other specified place
0.643 0.356 0.000
W19.5 Trade and service area
0.643 0.356 0.000
W19.0 Home
0.643 0.356 0.000
W19.7 Farm
0.643 0.356 0.000
W19.6 Industrial and construction area
0.643 0.356 0.000
W19.1 Residential institution
0.643 0.356 0.000
G44.4 Drug-induced headache, not elsewhere classified
0.643 0.357 0.000
R80 Isolated proteinuria
0.641 0.359 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.639 0.360 0.000
M24.5 Contracture of joint
0.639 0.361 0.000
M24.2 Disorder of ligament
0.639 0.361 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.637 0.363 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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