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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs73250776
log Bayes Factor = 15.8949
Chromosome 4   position 23,408,210  (GRCh37) Explore rs73250776 on Ensembl!
Variant rs73250776 is part of Cluster X0126

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
Chapter I Certain infectious and parasitic diseases
0.998 0.002 0.000
M70-M79 Other soft tissue disorders
0.998 0.002 0.000
I30-I52 Other forms of heart disease
0.994 0.006 0.000
M75 Shoulder lesions
0.994 0.006 0.000
Chapter V Mental and behavioural disorders
0.993 0.007 0.000
M75.4 Impingement syndrome of shoulder
0.990 0.010 0.000
M50-M54 Other dorsopathies
0.988 0.012 0.000
B95-B98 Bacterial, viral and other infectious agents
0.985 0.015 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.978 0.022 0.000
Chapter VI Diseases of the nervous system
0.976 0.024 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.974 0.026 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.971 0.029 0.000
M54 Dorsalgia
0.970 0.030 0.000
S00-S09 Injuries to the head
0.969 0.031 0.000
M45-M49 Spondylopathies
0.967 0.033 0.000
I20-I25 Ischaemic heart diseases
0.964 0.036 0.000
R50-R69 General symptoms and signs
0.964 0.036 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.962 0.038 0.000
Chapter XXI Factors influencing health status and contact with health services
0.958 0.042 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.958 0.042 0.000
I51 Complications and ill-defined descriptions of heart disease
0.952 0.048 0.000
M47 Spondylosis
0.950 0.050 0.000
G90-G99 Other disorders of the nervous system
0.945 0.055 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.938 0.062 0.000
F10.2 Dependence syndrome
0.930 0.070 0.000
M47.8 Other spondylosis
0.928 0.072 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.927 0.073 0.000
I51.7 Cardiomegaly
0.926 0.074 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.925 0.075 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.925 0.075 0.000
R55 Syncope and collapse
0.924 0.076 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.921 0.079 0.000
S02 Fracture of skull and facial bones
0.921 0.079 0.000
Chapter XX External causes of morbidity and mortality
0.915 0.085 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.914 0.086 0.000
M54.5 Low back pain
0.905 0.095 0.000
M47.86 Other spondylosis (Lumbar region)
0.900 0.100 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.896 0.104 0.000
I25 Chronic ischaemic heart disease
0.892 0.108 0.000
M54.9 Dorsalgia, unspecified
0.891 0.109 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.884 0.116 0.000
S60-S69 Injuries to the wrist and hand
0.882 0.118 0.000
M15-M19 Arthrosis
0.877 0.123 0.000
G93 Other disorders of brain
0.876 0.124 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.871 0.129 0.000
Chapter X Diseases of the respiratory system
0.870 0.130 0.000
I34 Nonrheumatic mitral valve disorders
0.869 0.131 0.000
A00-A09 Intestinal infectious diseases
0.868 0.132 0.000
O60-O75 Complications of labour and delivery
0.864 0.136 0.000
I20 Angina pectoris
0.864 0.136 0.000
M75.5 Bursitis of shoulder
0.863 0.137 0.000
E20-E35 Disorders of other endocrine glands
0.862 0.138 0.000
Z92 Personal history of medical treatment
0.861 0.139 0.000
I50 Heart failure
0.858 0.142 0.000
I46 Cardiac arrest
0.857 0.143 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.857 0.143 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.855 0.145 0.000
R51 Headache
0.855 0.145 0.000
J44 Other chronic obstructive pulmonary disease
0.855 0.145 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.855 0.145 0.000
J40-J47 Chronic lower respiratory diseases
0.854 0.146 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.852 0.148 0.000
M80-M85 Disorders of bone density and structure
0.847 0.153 0.000
M17 Gonarthrosis [arthrosis of knee]
0.847 0.153 0.000
M51 Other intervertebral disk disorders
0.844 0.156 0.000
R63 Symptoms and signs concerning food and fluid intake
0.842 0.158 0.000
I25.2 Old myocardial infarction
0.840 0.160 0.000
W00-W19 Falls
0.839 0.161 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.838 0.162 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.838 0.162 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.838 0.162 0.000
I38 Endocarditis, valve unspecified
0.836 0.164 0.000
B35-B49 Mycoses
0.835 0.165 0.000
R60 Oedema, not elsewhere classified
0.832 0.168 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.831 0.169 0.000
F30-F39 Mood [affective] disorders
0.831 0.169 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.831 0.169 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.831 0.169 0.000
A30-A49 Other bacterial diseases
0.830 0.170 0.000
S06 Intracranial injury
0.829 0.171 0.000
Z80 Family history of malignant neoplasm
0.828 0.172 0.000
M54.57 Low back pain (Lumbosacral region)
0.822 0.178 0.000
M20-M25 Other joint disorders
0.821 0.179 0.000
Chapter XXII Codes for special purposes
0.820 0.180 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.820 0.180 0.000
A04 Other bacterial intestinal infections
0.819 0.181 0.000
F10.4 Withdrawal state with delirium
0.819 0.181 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.818 0.182 0.000
M47.9 Spondylosis, unspecified
0.818 0.182 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.817 0.183 0.000
I70 Atherosclerosis
0.817 0.183 0.000
G20-G26 Extrapyramidal and movement disorders
0.816 0.184 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.813 0.187 0.000
M79.6 Pain in limb
0.812 0.188 0.000
I51.9 Heart disease, unspecified
0.812 0.188 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.811 0.189 0.000
M17.9 Gonarthrosis, unspecified
0.811 0.189 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.809 0.191 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.808 0.192 0.000
I35 Nonrheumatic aortic valve disorders
0.805 0.195 0.000
I71 Aortic aneurysm and dissection
0.805 0.195 0.000
O80-O84 Delivery
0.804 0.196 0.000
M71 Other bursopathies
0.804 0.196 0.000
M77 Other enthesopathies
0.803 0.197 0.000
Z80.3 Family history of malignant neoplasm of breast
0.801 0.199 0.000
I77 Other disorders of arteries and arterioles
0.800 0.200 0.000
E00-E07 Disorders of thyroid gland
0.799 0.201 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.798 0.202 0.000
M65-M68 Disorders of synovium and tendon
0.798 0.202 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.798 0.202 0.000
O48 Prolonged pregnancy
0.797 0.203 0.000
I50.1 Left ventricular failure
0.797 0.203 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.797 0.203 0.000
I30 Acute pericarditis
0.795 0.205 0.000
F60-F69 Disorders of adult personality and behaviour
0.792 0.208 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.792 0.208 0.000
S02.2 Fracture of nasal bones
0.792 0.208 0.000
S80-S89 Injuries to the knee and lower leg
0.791 0.209 0.000
I20.1 Angina pectoris with documented spasm
0.791 0.209 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.791 0.209 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.788 0.212 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.788 0.212 0.000
M54.59 Low back pain (Site unspecified)
0.787 0.213 0.000
I05-I09 Chronic rheumatic heart diseases
0.787 0.213 0.000
M54.4 Lumbago with sciatica
0.787 0.213 0.000
G30-G32 Other degenerative diseases of the nervous system
0.785 0.215 0.000
S20-S29 Injuries to the thorax
0.785 0.215 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.784 0.216 0.000
S01 Open wound of head
0.783 0.217 0.000
S02.1 Fracture of base of skull
0.783 0.217 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.783 0.217 0.000
F10.3 Withdrawal state
0.781 0.219 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.780 0.220 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.776 0.224 0.000
Chapter VII Diseases of the eye and adnexa
0.776 0.224 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.775 0.225 0.000
I36 Nonrheumatic tricuspid valve disorders
0.770 0.230 0.000
S90-S99 Injuries to the ankle and foot
0.769 0.230 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.769 0.230 0.000
R54 Senility
0.768 0.231 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.768 0.232 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.766 0.234 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.766 0.234 0.000
R47-R49 Symptoms and signs involving speech and voice
0.766 0.234 0.000
F10.0 Acute intoxication
0.764 0.236 0.000
T86 Failure and rejection of transplanted organs and tissues
0.764 0.236 0.000
I34.0 Mitral (valve) insufficiency
0.764 0.236 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.761 0.239 0.000
R61 Hyperhidrosis
0.760 0.240 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.759 0.240 0.000
A49 Bacterial infection of unspecified site
0.759 0.241 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.759 0.241 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.759 0.241 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.759 0.241 0.000
G93.8 Other specified disorders of brain
0.758 0.242 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.757 0.243 0.000
O70 Perineal laceration during delivery
0.756 0.244 0.000
Z92.3 Personal history of irradiation
0.756 0.244 0.000
R56 Convulsions, not elsewhere classified
0.756 0.244 0.000
M75.1 Rotator cuff syndrome
0.753 0.246 0.000
I46.9 Cardiac arrest, unspecified
0.753 0.247 0.000
M75.2 Bicipital tendinitis
0.753 0.247 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.753 0.247 0.000
Z22 Carrier of infectious disease
0.753 0.247 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.753 0.247 0.000
M54.6 Pain in thoracic spine
0.752 0.248 0.000
S02.4 Fracture of malar and maxillary bones
0.752 0.248 0.000
F99-F99 Unspecified mental disorder
0.747 0.253 0.000
W19 Unspecified fall
0.747 0.253 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.747 0.253 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.746 0.254 0.000
R27 Other lack of coordination
0.746 0.254 0.000
R60.0 Localised oedema
0.746 0.254 0.000
Z36 Antenatal screening
0.745 0.255 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.744 0.256 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.744 0.256 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.743 0.257 0.000
I42 Cardiomyopathy
0.743 0.257 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.742 0.258 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.741 0.259 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.740 0.259 0.000
G91 Hydrocephalus
0.740 0.260 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.740 0.260 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.739 0.261 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.738 0.262 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.736 0.264 0.000
S61 Open wound of wrist and hand
0.734 0.265 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.734 0.266 0.000
I22 Subsequent myocardial infarction
0.733 0.267 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.733 0.267 0.000
S09 Other and unspecified injuries of head
0.732 0.268 0.000
T66-T78 Other and unspecified effects of external causes
0.732 0.268 0.000
M50 Cervical disk disorders
0.731 0.268 0.000
M84 Disorders of continuity of bone
0.731 0.269 0.000
R52 Pain, not elsewhere classified
0.730 0.270 0.000
Z89 Acquired absence of limb
0.729 0.271 0.000
Z83 Family history of other specific disorders
0.729 0.271 0.000
S60 Superficial injury of wrist and hand
0.728 0.271 0.000
I49 Other cardiac arrhythmias
0.727 0.273 0.000
G93.3 Postviral fatigue syndrome
0.727 0.273 0.000
A04.8 Other specified bacterial intestinal infections
0.726 0.274 0.000
M17.1 Other primary gonarthrosis
0.725 0.275 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.723 0.277 0.000
E23 Hypofunction and other disorders of pituitary gland
0.723 0.277 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.722 0.278 0.000
B07 Viral warts
0.721 0.279 0.000
Z85 Personal history of malignant neoplasm
0.721 0.279 0.000
M46 Other inflammatory spondylopathies
0.720 0.280 0.000
B25-B34 Other viral diseases
0.720 0.280 0.000
B37 Candidiasis
0.719 0.281 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.718 0.282 0.000
M79.66 Pain in limb (Lower leg)
0.718 0.282 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.718 0.282 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.283 0.000
B99-B99 Other infectious diseases
0.716 0.284 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.716 0.284 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.716 0.284 0.000
B65-B83 Helminthiases
0.716 0.284 0.000
B50-B64 Protozoal diseases
0.716 0.284 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.716 0.284 0.000
B15-B19 Viral hepatitis
0.716 0.284 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.716 0.284 0.000
A80-A89 Viral infections of the central nervous system
0.716 0.284 0.000
A75-A79 Rickettsioses
0.716 0.284 0.000
A70-A74 Other diseases caused by chlamydiae
0.716 0.284 0.000
A65-A69 Other spirochaetal diseases
0.716 0.284 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.716 0.284 0.000
A20-A28 Certain zoonotic bacterial diseases
0.716 0.284 0.000
A15-A19 Tuberculosis
0.716 0.284 0.000
F20 Schizophrenia
0.716 0.284 0.000
M76 Enthesopathies of lower limb, excluding foot
0.716 0.284 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.716 0.284 0.000
I33 Acute and subacute endocarditis
0.715 0.285 0.000
Z88.6 Personal history of allergy to analgesic agent
0.715 0.285 0.000
I52 Other heart disorders in diseases classified elsewhere
0.713 0.287 0.000
I48 Atrial fibrillation and flutter
0.713 0.287 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.713 0.287 0.000
I41 Myocarditis in diseases classified elsewhere
0.713 0.287 0.000
I40 Acute myocarditis
0.713 0.287 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.713 0.287 0.000
I37 Pulmonary valve disorders
0.713 0.287 0.000
I32 Pericarditis in diseases classified elsewhere
0.713 0.287 0.000
O70.1 Second degree perineal laceration during delivery
0.713 0.287 0.000
M75.8 Other shoulder lesions
0.712 0.287 0.000
M75.9 Shoulder lesion, unspecified
0.712 0.287 0.000
M40-M43 Deforming dorsopathies
0.712 0.288 0.000
R29.6 Tendency to fall, not elsewhere classified
0.712 0.288 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.712 0.288 0.000
F80-F89 Disorders of psychological development
0.712 0.288 0.000
F70-F79 Mental retardation
0.712 0.288 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.712 0.288 0.000
Z86 Personal history of certain other diseases
0.711 0.289 0.000
J95-J99 Other diseases of the respiratory system
0.711 0.289 0.000
M53 Other dorsopathies, not elsewhere classified
0.708 0.291 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.708 0.292 0.000
Z82.3 Family history of stroke
0.708 0.292 0.000
Z93 Artificial opening status
0.706 0.294 0.000
M54.50 Low back pain (Multiple sites in spine)
0.704 0.295 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.704 0.296 0.000
O00-O08 Pregnancy with abortive outcome
0.704 0.296 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.704 0.296 0.000
R63.0 Anorexia
0.704 0.296 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.703 0.297 0.000
I24 Other acute ischaemic heart diseases
0.703 0.297 0.000
T87 Complications peculiar to reattachment and amputation
0.701 0.299 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.701 0.299 0.000
M25 Other joint disorders, not elsewhere classified
0.701 0.299 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.700 0.300 0.000
W08 Fall involving other furniture
0.700 0.300 0.000
G70-G73 Diseases of myoneural junction and muscle
0.700 0.300 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.700 0.300 0.000
S02.20 Fracture of nasal bones (closed)
0.700 0.300 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.699 0.301 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.699 0.301 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.699 0.301 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.699 0.301 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.699 0.301 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.699 0.301 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.699 0.301 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.699 0.301 0.000
F11 Mental and behavioural disorders due to use of opioids
0.699 0.301 0.000
O63 Long labour
0.697 0.303 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.696 0.304 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.696 0.304 0.000
M54.8 Other dorsalgia
0.696 0.304 0.000
M54.1 Radiculopathy
0.696 0.304 0.000
M54.0 Panniculitis affecting regions of neck and back
0.696 0.304 0.000
S08 Traumatic amputation of part of head
0.695 0.305 0.000
S07 Crushing injury of head
0.695 0.305 0.000
S05 Injury of eye and orbit
0.695 0.305 0.000
S04 Injury of cranial nerves
0.695 0.305 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.695 0.305 0.000
Z80.9 Family history of malignant neoplasm, unspecified
0.695 0.305 0.000
S40-S49 Injuries to the shoulder and upper arm
0.694 0.306 0.000
E10-E14 Diabetes mellitus
0.694 0.306 0.000
S02.5 Fracture of tooth
0.694 0.306 0.000
M49 Spondylopathies in diseases classified elsewhere
0.694 0.306 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.692 0.308 0.000
T39.1 4-Aminophenol derivatives
0.692 0.308 0.000
R63.4 Abnormal weight loss
0.692 0.308 0.000
I23 Certain current complications following acute myocardial infarction
0.691 0.308 0.000
R68 Other general symptoms and signs
0.691 0.309 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.691 0.309 0.000
R62 Lack of expected normal physiological development
0.691 0.309 0.000
R57 Shock, not elsewhere classified
0.691 0.309 0.000
R64 Cachexia
0.691 0.309 0.000
R58 Haemorrhage, not elsewhere classified
0.691 0.309 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.691 0.309 0.000
G96 Other disorders of central nervous system
0.691 0.309 0.000
I25.5 Ischaemic cardiomyopathy
0.691 0.309 0.000
F10.9 Unspecified mental and behavioural disorder
0.690 0.310 0.000
F10.8 Other mental and behavioural disorders
0.690 0.310 0.000
F10.7 Residual and late-onset psychotic disorder
0.690 0.310 0.000
F10.6 Amnesic syndrome
0.690 0.310 0.000
F10.5 Psychotic disorder
0.690 0.310 0.000
M86-M90 Other osteopathies
0.689 0.310 0.000
T81 Complications of procedures, not elsewhere classified
0.689 0.311 0.000
I25.3 Aneurysm of heart
0.689 0.311 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.689 0.311 0.000
O85-O92 Complications predominantly related to the puerperium
0.687 0.313 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.686 0.314 0.000
E22 Hyperfunction of pituitary gland
0.686 0.314 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.685 0.315 0.000
O80 Single spontaneous delivery
0.685 0.315 0.000
S02.6 Fracture of mandible
0.685 0.315 0.000
S61.8 Open wound of other parts of wrist and hand
0.685 0.315 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.685 0.315 0.000
R25 Abnormal involuntary movements
0.684 0.316 0.000
G20 Parkinson's disease
0.684 0.316 0.000
S02.10 Fracture of base of skull (closed)
0.684 0.316 0.000
S50-S59 Injuries to the elbow and forearm
0.683 0.317 0.000
M19 Other arthrosis
0.683 0.317 0.000
I70.0 Atherosclerosis of aorta
0.683 0.317 0.000
I51.6 Cardiovascular disease, unspecified
0.683 0.317 0.000
I51.5 Myocardial degeneration
0.683 0.317 0.000
I51.4 Myocarditis, unspecified
0.683 0.317 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.683 0.317 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.683 0.317 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.683 0.317 0.000
I51.0 Cardiac septal defect, acquired
0.683 0.317 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.683 0.317 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.682 0.318 0.000
Z86.4 Personal history of psychoactive substance abuse
0.682 0.318 0.000
Z22.3 Carrier of other specified bacterial diseases
0.682 0.318 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.682 0.318 0.000
M47.1 Other spondylosis with myelopathy
0.681 0.319 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.681 0.319 0.000
O36 Maternal care for other known or suspected foetal problems
0.681 0.319 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.681 0.319 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.680 0.320 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.680 0.320 0.000
Z35 Supervision of high-risk pregnancy
0.680 0.320 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.680 0.320 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.679 0.321 0.000
H53-H54 Visual disturbances and blindness
0.679 0.321 0.000
S06.5 Traumatic subdural haemorrhage
0.679 0.321 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.678 0.322 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.678 0.322 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.677 0.323 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.677 0.323 0.000
G90 Disorders of autonomic nervous system
0.677 0.323 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.677 0.323 0.000
G92 Toxic encephalopathy
0.677 0.323 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.677 0.323 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.677 0.323 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.676 0.324 0.000
T51 Toxic effect of alcohol
0.676 0.324 0.000
F33 Recurrent depressive disorder
0.676 0.324 0.000
M79.64 Pain in limb (Hand)
0.676 0.324 0.000
M51.9 Intervertebral disk disorder, unspecified
0.676 0.324 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.675 0.324 0.000
M54.3 Sciatica
0.674 0.326 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.673 0.326 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.673 0.327 0.000
F10.1 Harmful use
0.673 0.327 0.000
A04.5 Campylobacter enteritis
0.673 0.327 0.000
F00 Dementia in Alzheimer's disease
0.673 0.327 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.672 0.327 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.672 0.327 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.672 0.327 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.672 0.327 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.672 0.327 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.672 0.327 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.672 0.327 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.672 0.327 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.672 0.327 0.000
T36 Poisoning by systemic antibiotics
0.672 0.327 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.672 0.327 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.672 0.328 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.671 0.329 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.671 0.329 0.000
M67 Other disorders of synovium and tendon
0.670 0.330 0.000
A49.8 Other bacterial infections of unspecified site
0.669 0.331 0.000
O62 Abnormalities of forces of labour
0.668 0.332 0.000
S70-S79 Injuries to the hip and thigh
0.667 0.333 0.000
H55-H59 Other disorders of eye and adnexa
0.666 0.334 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.666 0.334 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.666 0.334 0.000
Z29 Need for other prophylactic measures
0.666 0.334 0.000
M47.89 Other spondylosis (Site unspecified)
0.665 0.335 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.665 0.335 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.665 0.335 0.000
M47.84 Other spondylosis (Thoracic region)
0.665 0.335 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.665 0.335 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.665 0.335 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.665 0.335 0.000
I72 Other aneurysm
0.665 0.335 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.665 0.335 0.000
M71.2 Synovial cyst of popliteal space [Baker]
0.665 0.335 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.664 0.336 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.664 0.336 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.663 0.336 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.663 0.336 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.663 0.336 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.663 0.337 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.663 0.337 0.000
G40-G47 Episodic and paroxysmal disorders
0.663 0.337 0.000
M31 Other necrotising vasculopathies
0.662 0.338 0.000
E40-E46 Malnutrition
0.660 0.340 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.660 0.340 0.000
S02.8 Fractures of other skull and facial bones
0.660 0.340 0.000
S02.7 Multiple fractures involving skull and facial bones
0.660 0.340 0.000
S02.3 Fracture of orbital floor
0.660 0.340 0.000
S02.0 Fracture of vault of skull
0.660 0.340 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.660 0.340 0.000
I60-I69 Cerebrovascular diseases
0.660 0.340 0.000
G30 Alzheimer's disease
0.659 0.340 0.000
L03 Cellulitis
0.659 0.341 0.000
S01.8 Open wound of other parts of head
0.659 0.341 0.000
H10-H13 Disorders of conjunctiva
0.659 0.341 0.000
R50 Fever of unknown origin
0.658 0.342 0.000
T85.2 Mechanical complication of intraocular lens
0.658 0.342 0.000
I34.1 Mitral (valve) prolapse
0.658 0.342 0.000
Z94 Transplanted organ and tissue status
0.658 0.342 0.000
I80 Phlebitis and thrombophlebitis
0.657 0.343 0.000
R05 Cough
0.657 0.343 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.656 0.344 0.000
Y35-Y36 Legal intervention and operations of war
0.656 0.344 0.000
Y10-Y34 Event of undetermined intent
0.656 0.344 0.000
Y00-Y09 Assault
0.656 0.344 0.000
X85-X99 Assault
0.656 0.344 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.656 0.344 0.000
X50-X57 Overexertion, travel and privation
0.656 0.344 0.000
X30-X39 Exposure to forces of nature
0.656 0.344 0.000
X20-X29 Contact with venomous animals and plants
0.656 0.344 0.000
X10-X19 Contact with heat and hot substances
0.656 0.344 0.000
X00-X09 Exposure to smoke, fire and flames
0.656 0.344 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.656 0.344 0.000
W75-W84 Other accidental threats to breathing
0.656 0.344 0.000
W65-W74 Accidental drowning and submersion
0.656 0.344 0.000
W50-W64 Exposure to animate mechanical forces
0.656 0.344 0.000
V98-V99 Other and unspecified transport accidents
0.656 0.344 0.000
V95-V97 Air and space transport accidents
0.656 0.344 0.000
V90-V94 Water transport accidents
0.656 0.344 0.000
V80-V89 Other land transport accidents
0.656 0.344 0.000
V70-V79 Bus occupant injured in transport accident
0.656 0.344 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.656 0.344 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.656 0.344 0.000
V40-V49 Car occupant injured in transport accident
0.656 0.344 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.656 0.344 0.000
V20-V29 Motorcycle rider injured in transport accident
0.656 0.344 0.000
V01-V09 Pedestrian injured in transport accident
0.656 0.344 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.656 0.344 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.655 0.344 0.000
Z84 Family history of other conditions
0.655 0.344 0.000
Z81 Family history of mental and behavioural disorders
0.655 0.344 0.000
X60-X84 Intentional self-harm
0.655 0.344 0.000
E21.0 Primary hyperparathyroidism
0.655 0.345 0.000
Y52 Agents primarily affecting the cardiovascular system
0.655 0.345 0.000
O43 Placental disorders
0.654 0.346 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.654 0.346 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.654 0.346 0.000
I35.0 Aortic (valve) stenosis
0.653 0.347 0.000
I30.9 Acute pericarditis, unspecified
0.653 0.347 0.000
Z57 Occupational exposure to risk-factors
0.653 0.347 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.653 0.347 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.653 0.347 0.000
L08 Other local infections of skin and subcutaneous tissue
0.652 0.348 0.000
Z36.0 Antenatal screening for chromosomal anomalies
0.650 0.350 0.000
I20.9 Angina pectoris, unspecified
0.650 0.350 0.000
M47.2 Other spondylosis with radiculopathy
0.650 0.350 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.649 0.351 0.000
M54.55 Low back pain (Thoracolumbar region)
0.649 0.351 0.000
M54.54 Low back pain-Thoracic
0.649 0.351 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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