TreeWAS – Variant ID: rs73336408

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter II Neoplasms	1.000	0.000
Chapter X Diseases of the respiratory system	1.000	0.000
J90 Pleural effusion, not elsewhere classified	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
J90-J94 Other diseases of pleura	1.000	0.000
Chapter XX External causes of morbidity and mortality	1.000	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.999	0.001
Chapter VI Diseases of the nervous system	0.997	0.003
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.994	0.006
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.993	0.007
Y83.1 Surgical operation with implant of artificial internal device	0.989	0.011
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.987	0.013
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.986	0.014
C79 Secondary malignant neoplasm of other sites	0.983	0.017
C77.1 Intrathoracic lymph nodes	0.975	0.025
G50-G59 Nerve, nerve root and plexus disorders	0.974	0.026
C64-C68 Malignant neoplasms of urinary tract	0.970	0.030
J09-J18 Influenza and pneumonia	0.960	0.040
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.959	0.041
C64 Malignant neoplasm of kidney, except renal pelvis	0.952	0.048
C77.2 Intra-abdominal lymph nodes	0.943	0.057
T84.1 Mechanical complication of internal fixation device of bones of limb	0.938	0.062
Y83.2 Surgical operation with anastomosis, bypass or graft	0.934	0.066
S90-S99 Injuries to the ankle and foot	0.930	0.070
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.929	0.071
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.924	0.076
T81 Complications of procedures, not elsewhere classified	0.923	0.077
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.914	0.086
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.910	0.090
C79.8 Secondary malignant neoplasm of other specified sites	0.910	0.090
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.906	0.094
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.903	0.097
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.900	0.100
G55.2 Nerve root and plexus compressions in spondylosis	0.900	0.100
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.898	0.102
C50-C50 Malignant neoplasm of breast	0.897	0.103
T81.4 Infection following a procedure, not elsewhere classified	0.894	0.106
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.886	0.114
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.885	0.115
G54 Nerve root and plexus disorders	0.885	0.115
J18 Pneumonia, organism unspecified	0.883	0.117
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.870	0.130
J95-J99 Other diseases of the respiratory system	0.865	0.135
G20-G26 Extrapyramidal and movement disorders	0.863	0.137
J18.9 Pneumonia, unspecified	0.862	0.138
D37-D48 Neoplasms of uncertain or unknown behaviour	0.861	0.139
Chapter VIII Diseases of the ear and mastoid process	0.860	0.140
M05-M14 Inflammatory polyarthropathies	0.858	0.142
C77.0 Lymph nodes of head, face and neck	0.857	0.143
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.854	0.146
G80-G83 Cerebral palsy and other paralytic syndromes	0.854	0.146
S92 Fracture of foot, except ankle	0.851	0.149
G57 Mononeuropathies of lower limb	0.851	0.149
G90-G99 Other disorders of the nervous system	0.850	0.150
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.846	0.154
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.843	0.157
T84.0 Mechanical complication of internal joint prosthesis	0.841	0.159
T92 Sequelae of injuries of upper limb	0.837	0.163
S10-S19 Injuries to the neck	0.837	0.163
W20-W49 Exposure to inanimate mechanical forces	0.835	0.165
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.835	0.165
C79.7 Secondary malignant neoplasm of adrenal gland	0.835	0.165
J86 Pyothorax	0.834	0.166
M45-M49 Spondylopathies	0.833	0.167
Y95 Nosocomial condition	0.833	0.167
S20-S29 Injuries to the thorax	0.828	0.172
J13 Pneumonia due to Streptococcus pneumoniae	0.828	0.172
D00-D09 In situ neoplasms	0.826	0.174
C50 Malignant neoplasm of breast	0.824	0.176
Y00-Y09 Assault	0.823	0.177
H90-H95 Other disorders of ear	0.815	0.185
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.814	0.186
S70-S79 Injuries to the hip and thigh	0.814	0.186
T15-T19 Effects of foreign body entering through natural orifice	0.809	0.191
G20 Parkinson's disease	0.809	0.191
G58 Other mononeuropathies	0.805	0.195
J93 Pneumothorax	0.802	0.198
M80-M85 Disorders of bone density and structure	0.800	0.200
J98 Other respiratory disorders	0.800	0.200
T85 Complications of other internal prosthetic devices, implants and grafts	0.799	0.201
Y83.9 Surgical procedure, unspecified	0.799	0.201
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.799	0.201
T86 Failure and rejection of transplanted organs and tissues	0.798	0.202
C34 Malignant neoplasm of bronchus and lung	0.797	0.203
Y83.5 Amputation of limb(s)	0.795	0.205
Chapter XII Diseases of the skin and subcutaneous tissue	0.795	0.205
M40-M43 Deforming dorsopathies	0.793	0.207
C80 Malignant neoplasm without specification of site	0.793	0.207
H91 Other hearing loss	0.791	0.209
S40-S49 Injuries to the shoulder and upper arm	0.789	0.211
J86.9 Pyothorax without fistula	0.785	0.215
J91 Pleural effusion in conditions classified elsewhere	0.774	0.226
H91.9 Hearing loss, unspecified	0.774	0.226
J15 Bacterial pneumonia, not elsewhere classified	0.773	0.226
T79-T79 Certain early complications of trauma	0.773	0.227
X58-X59 Accidental exposure to other and unspecified factors	0.772	0.228
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.772	0.228
S99 Other and unspecified injuries of ankle and foot	0.772	0.228
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.771	0.229
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.771	0.229
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.770	0.230
D70-D77 Other diseases of blood and blood-forming organs	0.769	0.231
S60-S69 Injuries to the wrist and hand	0.769	0.231
C50.9 Breast, unspecified	0.768	0.232
M07 Psoriatic and enteropathic arthropathies	0.766	0.234
G62 Other polyneuropathies	0.766	0.234
Y83.3 Surgical operation with formation of external stoma	0.765	0.235
Q60-Q64 Congenital malformations of the urinary system	0.761	0.238
J94 Other pleural conditions	0.759	0.240
G95 Other diseases of spinal cord	0.759	0.241
G63 Polyneuropathy in diseases classified elsewhere	0.759	0.241
T20-T25 Burns and corrosions of external body surface, specified by site	0.759	0.241
M05 Seropositive rheumatoid arthritis	0.759	0.241
G35-G37 Demyelinating diseases of the central nervous system	0.759	0.241
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.757	0.243
T92.1 Sequelae of fracture of arm	0.754	0.246
T66-T78 Other and unspecified effects of external causes	0.752	0.247
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.751	0.249
C34.9 Bronchus or lung, unspecified	0.751	0.249
X40-X49 Accidental poisoning by and exposure to noxious substances	0.749	0.251
T59 Toxic effect of other gases, fumes and vapours	0.745	0.255
C66 Malignant neoplasm of ureter	0.744	0.256
S92.0 Fracture of calcaneus	0.743	0.257
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.742	0.258
M48 Other spondylopathies	0.742	0.258
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.741	0.259
V80-V89 Other land transport accidents	0.737	0.263
C45 Mesothelioma	0.737	0.263
T51 Toxic effect of alcohol	0.737	0.263
C73 Malignant neoplasm of thyroid gland	0.737	0.263
G54.4 Lumbosacral root disorders, not elsewhere classified	0.736	0.264
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.734	0.266
X20-X29 Contact with venomous animals and plants	0.734	0.266
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.732	0.268
G70-G73 Diseases of myoneural junction and muscle	0.731	0.269
G54.9 Nerve root and plexus disorder, unspecified	0.729	0.271
L80-L99 Other disorders of the skin and subcutaneous tissue	0.729	0.271
G55.0 Nerve root and plexus compressions in neoplastic disease	0.728	0.272
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.728	0.272
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.728	0.272
G91 Hydrocephalus	0.726	0.274
T93 Sequelae of injuries of lower limb	0.726	0.274
M41 Scoliosis	0.726	0.274
V20-V29 Motorcycle rider injured in transport accident	0.724	0.276
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.723	0.277
W50-W64 Exposure to animate mechanical forces	0.721	0.279
G00-G09 Inflammatory diseases of the central nervous system	0.721	0.279
M06 Other rheumatoid arthritis	0.721	0.279
Y86 Sequelae of other accidents	0.720	0.280
D06 Carcinoma in situ of cervix uteri	0.719	0.281
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.717	0.283
M86-M90 Other osteopathies	0.717	0.283
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
Y35-Y36 Legal intervention and operations of war	0.717	0.283
Y10-Y34 Event of undetermined intent	0.717	0.283
X85-X99 Assault	0.717	0.283
X50-X57 Overexertion, travel and privation	0.717	0.283
X30-X39 Exposure to forces of nature	0.717	0.283
X10-X19 Contact with heat and hot substances	0.717	0.283
X00-X09 Exposure to smoke, fire and flames	0.717	0.283
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.717	0.283
W75-W84 Other accidental threats to breathing	0.717	0.283
W65-W74 Accidental drowning and submersion	0.717	0.283
V98-V99 Other and unspecified transport accidents	0.717	0.283
V95-V97 Air and space transport accidents	0.717	0.283
V90-V94 Water transport accidents	0.717	0.283
V70-V79 Bus occupant injured in transport accident	0.717	0.283
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.717	0.283
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.717	0.283
V40-V49 Car occupant injured in transport accident	0.717	0.283
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.717	0.283
V01-V09 Pedestrian injured in transport accident	0.717	0.283
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.716	0.284
C76 Malignant neoplasm of other and ill-defined sites	0.716	0.284
C65 Malignant neoplasm of renal pelvis	0.715	0.285
Q00-Q07 Congenital malformations of the nervous system	0.715	0.285
Y85 Sequelae of transport accidents	0.714	0.286
G54.0 Brachial plexus disorders	0.712	0.288
T56 Toxic effect of metals	0.709	0.291
G90 Disorders of autonomic nervous system	0.709	0.291
L40-L45 Papulosquamous disorders	0.709	0.291
C50.2 Upper-inner quadrant of breast	0.708	0.292
J10 Influenza due to identified influenza virus	0.706	0.294
Y45.0 Opioids and related analgesics	0.705	0.295
C79.6 Secondary malignant neoplasm of ovary	0.705	0.295
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.705	0.295
T81.9 Unspecified complication of procedure	0.704	0.296
G57.6 Lesion of plantar nerve	0.704	0.296
G60 Hereditary and idiopathic neuropathy	0.703	0.296
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.703	0.297
C77.8 Lymph nodes of multiple regions	0.701	0.299
M07.3 Other psoriatic arthropathies	0.700	0.300
G83 Other paralytic syndromes	0.700	0.300
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.699	0.301
M91-M94 Chondropathies	0.699	0.301
G53 Cranial nerve disorders in diseases classified elsewhere	0.698	0.301
G52 Disorders of other cranial nerves	0.698	0.301
T91 Sequelae of injuries of neck and trunk	0.698	0.302
D10-D36 Benign neoplasms	0.698	0.302
J93.9 Pneumothorax, unspecified	0.697	0.303
C50.5 Lower-outer quadrant of breast	0.697	0.303
Y04 Assault by bodily force	0.697	0.303
C79.2 Secondary malignant neoplasm of skin	0.696	0.304
T90 Sequelae of injuries of head	0.696	0.304
C68 Malignant neoplasm of other and unspecified urinary organs	0.695	0.305
G57.8 Other mononeuropathies of lower limb	0.695	0.305
L98.9 Disorder of skin and subcutaneous tissue, unspecified	0.694	0.306
W22 Striking against or struck by other objects	0.694	0.306
T87 Complications peculiar to reattachment and amputation	0.693	0.307
Y60-Y69 Misadventures to patients during surgical and medical care	0.693	0.307
S92.3 Fracture of metatarsal bone	0.692	0.308
Q80-Q89 Other congenital malformations	0.692	0.308
D47.2 Monoclonal gammopathy	0.690	0.310
D47.3 Essential (haemorrhagic) thrombocythaemia	0.689	0.311
T98 Sequelae of other and unspecified effects of external causes	0.689	0.311
J17 Pneumonia in diseases classified elsewhere	0.688	0.312
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.688	0.312
J12 Viral pneumonia, not elsewhere classified	0.688	0.312
J14 Pneumonia due to Haemophilus influenzae	0.688	0.312
J09 Influenza due to certain identified influenza virus	0.688	0.312
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.688	0.312
M05.9 Seropositive rheumatoid arthritis, unspecified	0.688	0.312
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.687	0.312
H90 Conductive and sensorineural hearing loss	0.687	0.313
J98.8 Other specified respiratory disorders	0.686	0.314
C51-C58 Malignant neoplasms of female genital organs	0.686	0.314
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.685	0.314
W49 Exposure to other and unspecified inanimate mechanical forces	0.684	0.316
T86.1 Kidney transplant failure and rejection	0.684	0.316
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.683	0.317
M80 Osteoporosis with pathological fracture	0.683	0.317
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.681	0.319
G50 Disorders of trigeminal nerve	0.680	0.320
D23 Other benign neoplasms of skin	0.679	0.321
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.679	0.321
Y89 Sequelae of other external causes	0.679	0.321
M41.9 Scoliosis, unspecified	0.678	0.322
J60-J70 Lung diseases due to external agents	0.677	0.323
G30-G32 Other degenerative diseases of the nervous system	0.677	0.323
Q61 Cystic kidney disease	0.676	0.324
T80 Complications following infusion, transfusion and therapeutic injection	0.676	0.324
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.676	0.324
S68 Traumatic amputation of wrist and hand	0.674	0.326
M50-M54 Other dorsopathies	0.674	0.326
Y83.8 Other surgical procedures	0.674	0.326
S91 Open wound of ankle and foot	0.673	0.327
Y91 Evidence of alcohol involvement determined by level of intoxication	0.673	0.327
M85 Other disorders of bone density and structure	0.672	0.328
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.671	0.329
Q20-Q28 Congenital malformations of the circulatory system	0.671	0.329
M14 Arthropathies in other diseases classified elsewhere	0.669	0.331
L40 Psoriasis	0.669	0.331
S22 Fracture of rib(s), sternum and thoracic spine	0.669	0.331
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.668	0.332
T85.4 Mechanical complication of breast prosthesis and implant	0.667	0.333
S98 Traumatic amputation of ankle and foot	0.666	0.333
S97 Crushing injury of ankle and foot	0.666	0.333
S96 Injury of muscle and tendon at ankle and foot level	0.666	0.333
S95 Injury of blood vessels at ankle and foot level	0.666	0.333
S94 Injury of nerves at ankle and foot level	0.666	0.333
S92.00 Fracture of calcaneus (closed)	0.666	0.334
T95 Sequelae of burns, corrosions and frostbite	0.666	0.334
T94 Sequelae of injuries involving multiple and unspecified body regions	0.666	0.334
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.666	0.334
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.666	0.334
M45 Ankylosing spondylitis	0.666	0.334
S50-S59 Injuries to the elbow and forearm	0.666	0.334
D09 Carcinoma in situ of other and unspecified sites	0.666	0.334
G58.9 Mononeuropathy, unspecified	0.665	0.335
S20 Superficial injury of thorax	0.664	0.336
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere	0.662	0.338
Chapter XXII Codes for special purposes	0.662	0.338
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.661	0.338
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.660	0.340
G80 Infantile cerebral palsy	0.660	0.340
S72 Fracture of femur	0.660	0.340
S99.9 Unspecified injury of ankle and foot	0.659	0.341
M60-M63 Disorders of muscles	0.659	0.341
Y83.4 Other reconstructive surgery	0.659	0.341
G63.2 Diabetic polyneuropathy	0.658	0.342
W23 Caught, crushed, jammed or pinched in or between objects	0.658	0.342
J98.0 Diseases of bronchus, not elsewhere classified	0.657	0.343
L89 Decubitus ulcer	0.657	0.343
X60-X84 Intentional self-harm	0.657	0.343
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.655	0.345
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.655	0.345
Q38-Q45 Other congenital malformations of the digestive system	0.655	0.345
Q35-Q37 Cleft lip and cleft palate	0.655	0.345
Q30-Q34 Congenital malformations of the respiratory system	0.655	0.345
T17 Foreign body in respiratory tract	0.655	0.345
D45 Polycythaemia vera	0.653	0.347
C32 Malignant neoplasm of larynx	0.653	0.347
C79.9 Secondary malignant neoplasm, unspecified site	0.653	0.347
G55.3 Nerve root and plexus compressions in other dorsopathies	0.651	0.349
T51.9 Alcohol, unspecified	0.651	0.349
Q50-Q56 Congenital malformations of genital organs	0.651	0.349
T84.3 Mechanical complication of other bone devices, implants and grafts	0.650	0.350
Y90 Evidence of alcohol involvement determined by blood alcohol level	0.650	0.350
Y98 Lifestyle-related condition	0.650	0.350
Y97 Environmental-pollution-related condition	0.650	0.350
Y96 Work-related condition	0.650	0.350
G62.8 Other specified polyneuropathies	0.650	0.350
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.649	0.351
V10-V19 Pedal cyclist injured in transport accident	0.649	0.351
G59 Mononeuropathy in diseases classified elsewhere	0.648	0.352
J85 Abscess of lung and mediastinum	0.648	0.352
C50.0 Nipple and areola	0.647	0.353
G64 Other disorders of peripheral nervous system	0.645	0.354
M00-M03 Infectious arthropathies	0.645	0.355
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.645	0.355
J98.4 Other disorders of lung	0.645	0.355
T65 Toxic effect of other and unspecified substances	0.644	0.356
T62 Toxic effect of other noxious substances eaten as food	0.644	0.356
T61 Toxic effect of noxious substances eaten as seafood	0.644	0.356
T60 Toxic effect of pesticides	0.644	0.356
T57 Toxic effect of other inorganic substances	0.644	0.356
T54 Toxic effect of corrosive substances	0.644	0.356
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.644	0.356
T52 Toxic effect of organic solvents	0.644	0.356
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.644	0.356
T58 Toxic effect of carbon monoxide	0.644	0.356
T55 Toxic effect of soaps and detergents	0.644	0.356
G81 Hemiplegia	0.643	0.357
D06.9 Cervix, unspecified	0.642	0.358
C45.0 Mesothelioma of pleura	0.642	0.358
M48.0 Spinal stenosis	0.642	0.358
S92.5 Fracture of other toe	0.641	0.359
D80-D89 Certain disorders involving the immune mechanism	0.641	0.359
T63 Toxic effect of contact with venomous animals	0.640	0.360
C50.1 Central portion of breast	0.640	0.360
S19 Other and unspecified injuries of neck	0.639	0.361
T81.3 Disruption of operation wound, not elsewhere classified	0.638	0.362
J11 Influenza, virus not identified	0.637	0.363
M46 Other inflammatory spondylopathies	0.637	0.363
G91.9 Hydrocephalus, unspecified	0.637	0.363
T84.2 Mechanical complication of internal fixation device of other bones	0.636	0.364
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.636	0.364
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.635	0.365
C38 Malignant neoplasm of heart, mediastinum and pleura	0.635	0.365
C31 Malignant neoplasm of accessory sinuses	0.635	0.365
C30 Malignant neoplasm of nasal cavity and middle ear	0.635	0.365
C37 Malignant neoplasm of thymus	0.635	0.365
C33 Malignant neoplasm of trachea	0.635	0.365
S46 Injury of muscle and tendon at shoulder and upper arm level	0.635	0.365
D73 Diseases of spleen	0.635	0.365
G54.8 Other nerve root and plexus disorders	0.634	0.365
G54.7 Phantom limb syndrome without pain	0.634	0.365
G54.6 Phantom limb syndrome with pain	0.634	0.365
G54.5 Neuralgic amyotrophy	0.634	0.365
G54.3 Thoracic root disorders, not elsewhere classified	0.634	0.365
G54.2 Cervical root disorders, not elsewhere classified	0.634	0.365
G54.1 Lumbosacral plexus disorders	0.634	0.365
D37.5 Rectum	0.634	0.366
J18.8 Other pneumonia, organism unspecified	0.633	0.367
J18.2 Hypostatic pneumonia, unspecified	0.633	0.367
D23.7 Skin of lower limb, including hip	0.633	0.367
S92.2 Fracture of other tarsal bone(s)	0.633	0.367
S70 Superficial injury of hip and thigh	0.632	0.368
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.632	0.368
C69 Malignant neoplasm of eye and adnexa	0.631	0.369
D55-D59 Haemolytic anaemias	0.630	0.370
Y49 Psychotropic drugs, not elsewhere classified	0.629	0.371
T81.7 Vascular complications following a procedure, not elsewhere classified	0.628	0.372
G57.1 Meralgia paraesthetica	0.627	0.373
G95.8 Other specified diseases of spinal cord	0.627	0.373
D26 Other benign neoplasms of uterus	0.626	0.374
G82 Paraplegia and tetraplegia	0.625	0.375
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.625	0.375
S12 Fracture of neck	0.625	0.375
M82 Osteoporosis in diseases classified elsewhere	0.625	0.375
D02 Carcinoma in situ of middle ear and respiratory system	0.624	0.376
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent	0.623	0.376
T59.9 Gases, fumes and vapours, unspecified	0.623	0.377
S90 Superficial injury of ankle and foot	0.623	0.377
L40.5 Arthropathic psoriasis	0.623	0.377
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.623	0.377
M07.39 Other psoriatic arthropathies (Site unspecified)	0.622	0.378
Y57 Other and unspecified drugs and medicaments	0.621	0.379
Y83.0 Surgical operation with transplant of whole organ	0.621	0.379
D72 Other disorders of white blood cells	0.621	0.379
M41.99 Scoliosis, unspecified (Site unspecified)	0.621	0.379
J96 Respiratory failure, not elsewhere classified	0.620	0.380
D04 Carcinoma in situ of skin	0.620	0.380
Y51 Drugs primarily affecting the autonomic nervous system	0.619	0.381
G23 Other degenerative diseases of basal ganglia	0.619	0.381
G21 Secondary Parkinsonism	0.619	0.381
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.619	0.381
G22 Parkinsonism in diseases classified elsewhere	0.619	0.381
J98.9 Respiratory disorder, unspecified	0.618	0.382
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.618	0.382
Y52 Agents primarily affecting the cardiovascular system	0.618	0.382
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.617	0.382
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.617	0.382
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.617	0.382
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.617	0.382
T92.2 Sequelae of fracture at wrist and hand level	0.616	0.383
C80.9 Malignant neoplasm, unspecified	0.616	0.384
M54 Dorsalgia	0.616	0.384
G95.1 Vascular myelopathies	0.616	0.384
M12 Other specific arthropathies	0.615	0.385
M09 Juvenile arthritis in diseases classified elsewhere	0.615	0.385
M08 Juvenile arthritis	0.615	0.385
J15.2 Pneumonia due to staphylococcus	0.613	0.387
T79 Certain early complications of trauma, not elsewhere classified	0.611	0.389
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.610	0.390
S92.9 Fracture of foot, unspecified	0.610	0.390
S92.7 Multiple fractures of foot	0.610	0.390
S92.4 Fracture of great toe	0.610	0.390
S92.1 Fracture of talus	0.610	0.390
G57.9 Mononeuropathy of lower limb, unspecified	0.610	0.390
G57.5 Tarsal tunnel syndrome	0.610	0.390
G57.4 Lesion of medial popliteal nerve	0.610	0.390
G57.3 Lesion of lateral popliteal nerve	0.610	0.390
G57.2 Lesion of femoral nerve	0.610	0.390
G57.0 Lesion of sciatic nerve	0.610	0.390
Y44 Agents primarily affecting blood constituents	0.610	0.390
G99 Other disorders of nervous system in diseases classified elsewhere	0.610	0.390
G94 Other disorders of brain in diseases classified elsewhere	0.610	0.390
G98 Other disorders of nervous system, not elsewhere classified	0.610	0.390
G92 Toxic encephalopathy	0.610	0.390
X59 Exposure to unspecified factor	0.609	0.390
T14 Injury of unspecified body region	0.609	0.391
G90.3 Multisystem degeneration	0.608	0.392
Y85.0 Sequelae of motor-vehicle accident	0.608	0.392
D47.1 Chronic myeloproliferative disease	0.607	0.393
C75 Malignant neoplasm of other endocrine glands and related structures	0.607	0.393
C74 Malignant neoplasm of adrenal gland	0.607	0.393
T18 Foreign body in alimentary tract	0.606	0.394
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.606	0.394
G58.8 Other specified mononeuropathies	0.606	0.394
Y04.8 Other specified place	0.606	0.394
M89 Other disorders of bone	0.606	0.394
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.605	0.394
C80.0 Malignant neoplasm, primary site unknown, so stated	0.605	0.395
S27 Injury of other and unspecified intrathoracic organs	0.605	0.395
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.605	0.395
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system	0.605	0.395
C46 Kaposi's sarcoma	0.605	0.395
Y83.6 Removal of other organ (partial) (total)	0.605	0.395
J93.8 Other pneumothorax	0.604	0.396
M48.5 Collapsed vertebra, not elsewhere classified	0.603	0.396
C34.3 Lower lobe, bronchus or lung	0.603	0.397
H60-H62 Diseases of external ear	0.602	0.398
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.602	0.398
D60-D64 Aplastic and other anaemias	0.602	0.398
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.601	0.399
S41 Open wound of shoulder and upper arm	0.600	0.400
T92.9 Sequelae of unspecified injury of upper limb	0.600	0.400
T92.8 Sequelae of other specified injuries of upper limb	0.600	0.400
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.600	0.400
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.600	0.400
T92.4 Sequelae of injury of nerve of upper limb	0.600	0.400
T92.0 Sequelae of open wound of upper limb	0.600	0.400
S17 Crushing injury of neck	0.600	0.400
S15 Injury of blood vessels at neck level	0.600	0.400
S14 Injury of nerves and spinal cord at neck level	0.600	0.400
S11 Open wound of neck	0.600	0.400
S10 Superficial injury of neck	0.600	0.400
S18 Traumatic amputation at neck level	0.600	0.400
S16 Injury of muscle and tendon at neck level	0.600	0.400
C77.4 Inguinal and lower limb lymph nodes	0.599	0.401
T68 Hypothermia	0.599	0.401
D32 Benign neoplasm of meninges	0.599	0.401
W46 Contact with hypodermic needle	0.599	0.401
W45 Foreign body or object entering through skin	0.599	0.401
W43 Exposure to vibration	0.599	0.401
W42 Exposure to noise	0.599	0.401
W41 Exposure to high-pressure jet	0.599	0.401
W40 Explosion of other materials	0.599	0.401
W39 Discharge of firework	0.599	0.401
W38 Explosion and rupture of other specified pressurised devices	0.599	0.401
W37 Explosion and rupture of pressurised tyre, pipe or hose	0.599	0.401
W36 Explosion and rupture of gas cylinder	0.599	0.401
W35 Explosion and rupture of boiler	0.599	0.401
W34 Discharge from other and unspecified firearms	0.599	0.401
W33 Rifle, shotgun and larger firearm discharge	0.599	0.401
W32 Handgun discharge	0.599	0.401
W31 Contact with other and unspecified machinery	0.599	0.401
W30 Contact with agricultural machinery	0.599	0.401
W28 Contact with powered lawn mower	0.599	0.401
W27 Contact with nonpowered hand tool	0.599	0.401
W26 Contact with knife, sword or dagger	0.599	0.401
W24 Contact with lifting and transmission devices, not elsewhere classified	0.599	0.401
W20 Struck by thrown, projected or falling object	0.599	0.401
Y59 Other and unspecified vaccines and biological substances	0.599	0.401
Y58 Bacterial vaccines	0.599	0.401
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.599	0.401
Y53 Agents primarily affecting the gastro-intestinal system	0.599	0.401
Y50 Central nervous system stimulants, not elsewhere classified	0.599	0.401
Y48 Anaesthetics and therapeutic gases	0.599	0.401
Y47 Sedatives, hypnotics and antianxiety drugs	0.599	0.401
Y46 Antiepileptics and anti-Parkinsonism drugs	0.599	0.401
J30-J39 Other diseases of upper respiratory tract	0.598	0.402
J86.0 Pyothorax with fistula	0.598	0.402
M49 Spondylopathies in diseases classified elsewhere	0.598	0.402

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations