TreeWAS – Variant ID: rs73431975

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
M81.99 Osteoporosis, unspecified (Site unspecified)	0.084	0.916
M81.9 Osteoporosis, unspecified	0.067	0.933
M81.98 Osteoporosis, unspecified (Other)	0.054	0.946
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.053	0.947
M81.96 Osteoporosis, unspecified (Lower leg)	0.048	0.952
M81.94 Osteoporosis, unspecified (Hand)	0.048	0.952
M81.93 Osteoporosis, unspecified (Forearm)	0.048	0.952
M81.92 Osteoporosis, unspecified (Upper arm)	0.048	0.952
M81.91 Osteoporosis, unspecified (Shoulder region)	0.048	0.952
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.047	0.952
M81 Osteoporosis without pathological fracture	0.047	0.952
H54.7 Unspecified visual loss	0.045	0.955
H54 Blindness and low vision	0.045	0.955
M81.90 Osteoporosis, unspecified (Multiple sites)	0.045	0.955
H54.4 Blindness, one eye	0.043	0.957
H53-H54 Visual disturbances and blindness	0.039	0.961
H54.5 Low vision, one eye	0.037	0.963
H54.0 Blindness, both eyes	0.037	0.963
M80-M85 Disorders of bone density and structure	0.036	0.964
M81.8 Other osteoporosis	0.034	0.966
M81.6 Localised osteoporosis [Lequesne]	0.034	0.966
M81.5 Idiopathic osteoporosis	0.034	0.966
M81.3 Postsurgical malabsorption osteoporosis	0.034	0.966
M81.2 Osteoporosis of disuse	0.034	0.966
M81.1 Postoophorectomy osteoporosis	0.034	0.966
M81.0 Postmenopausal osteoporosis	0.034	0.966
H53 Visual disturbances	0.033	0.967
H54.6 Unqualified visual loss, one eye	0.033	0.967
H54.3 Unqualified visual loss, both eyes	0.033	0.967
H54.2 Low vision, both eyes	0.033	0.967
H54.1 Blindness, one eye, low vision, other eye	0.033	0.967
M81.4 Drug-induced osteoporosis	0.032	0.968
H53.2 Diplopia	0.031	0.969
Chapter VII Diseases of the eye and adnexa	0.031	0.969
M84 Disorders of continuity of bone	0.030	0.970
H53.1 Subjective visual disturbances	0.028	0.972
H43-H45 Disorders of vitreous body and globe	0.028	0.972
M82 Osteoporosis in diseases classified elsewhere	0.027	0.972
M84.0 Malunion of fracture	0.027	0.973
M85 Other disorders of bone density and structure	0.027	0.973
H54.9 Unspecified visual impairment (binocular)	0.027	0.973
H55-H59 Other disorders of eye and adnexa	0.027	0.973
H53.8 Other visual disturbances	0.026	0.974
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.026	0.974
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.026	0.974
H46-H48 Disorders of optic nerve and visual pathways	0.026	0.974
M83 Adult osteomalacia	0.026	0.974
N48.6 Balanitis xerotica obliterans	0.025	0.975
H10-H13 Disorders of conjunctiva	0.025	0.975
Chapter XX External causes of morbidity and mortality	0.025	0.975
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.025	0.975
M81.08 Postmenopausal osteoporosis (Other)	0.025	0.975
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.025	0.975
M81.06 Postmenopausal osteoporosis (Lower leg)	0.025	0.975
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.025	0.975
M81.04 Postmenopausal osteoporosis (Hand)	0.025	0.975
M81.03 Postmenopausal osteoporosis (Forearm)	0.025	0.975
M81.02 Postmenopausal osteoporosis (Upper arm)	0.025	0.975
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.025	0.975
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.025	0.975
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.025	0.975
M81.18 Postoophorectomy osteoporosis (Other)	0.025	0.975
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.025	0.975
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.025	0.975
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.025	0.975
M81.14 Postoophorectomy osteoporosis (Hand)	0.025	0.975
M81.13 Postoophorectomy osteoporosis (Forearm)	0.025	0.975
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.025	0.975
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.025	0.975
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.025	0.975
M81.29 Osteoporosis of disuse (Site unspecified)	0.025	0.975
M81.28 Osteoporosis of disuse (Other)	0.025	0.975
M81.27 Osteoporosis of disuse (Ankle and foot)	0.025	0.975
M81.26 Osteoporosis of disuse (Lower leg)	0.025	0.975
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.025	0.975
M81.24 Osteoporosis of disuse (Hand)	0.025	0.975
M81.23 Osteoporosis of disuse (Forearm)	0.025	0.975
M81.22 Osteoporosis of disuse (Upper arm)	0.025	0.975
M81.21 Osteoporosis of disuse (Shoulder region)	0.025	0.975
M81.20 Osteoporosis of disuse (Multiple sites)	0.025	0.975
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.025	0.975
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.025	0.975
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.025	0.975
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.025	0.975
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.025	0.975
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.025	0.975
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.025	0.975
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.025	0.975
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.025	0.975
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.025	0.975
M81.59 Idiopathic osteoporosis (Site unspecified)	0.025	0.975
M81.58 Idiopathic osteoporosis (Other)	0.025	0.975
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.025	0.975
M81.56 Idiopathic osteoporosis (Lower leg)	0.025	0.975
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.025	0.975
M81.54 Idiopathic osteoporosis (Hand)	0.025	0.975
M81.53 Idiopathic osteoporosis (Forearm)	0.025	0.975
M81.52 Idiopathic osteoporosis (Upper arm)	0.025	0.975
M81.51 Idiopathic osteoporosis (Shoulder region)	0.025	0.975
M81.50 Idiopathic osteoporosis (Multiple sites)	0.025	0.975
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.025	0.975
M81.68 Localized osteoporosis [Lequesne] (Other)	0.025	0.975
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.025	0.975
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.025	0.975
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.025	0.975
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.025	0.975
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.025	0.975
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.025	0.975
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.025	0.975
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.025	0.975
M81.89 Other osteoporosis (Site unspecified)	0.025	0.975
M81.88 Other osteoporosis (Other)	0.025	0.975
M81.87 Other osteoporosis (Ankle and foot)	0.025	0.975
M81.86 Other osteoporosis (Lower leg)	0.025	0.975
M81.85 Other osteoporosis (Pelvic region and thigh)	0.025	0.975
M81.84 Other osteoporosis (Hand)	0.025	0.975
M81.83 Other osteoporosis (Forearm)	0.025	0.975
M81.82 Other osteoporosis (Upper arm)	0.025	0.975
M81.81 Other osteoporosis (Shoulder region)	0.025	0.975
M81.80 Other osteoporosis (Multiple sites)	0.025	0.975
Y52 Agents primarily affecting the cardiovascular system	0.025	0.975
W20-W49 Exposure to inanimate mechanical forces	0.025	0.975
M84.03 Malunion of fracture (Forearm)	0.024	0.975
N19 Unspecified renal failure	0.024	0.976
M80 Osteoporosis with pathological fracture	0.024	0.976
S20-S29 Injuries to the thorax	0.024	0.976
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.024	0.976
H53.6 Night blindness	0.024	0.976
H53.5 Colour vision deficiencies	0.024	0.976
H53.3 Other disorders of binocular vision	0.024	0.976
H43 Disorders of vitreous body	0.024	0.976
M81.49 Drug-induced osteoporosis (Site unspecified)	0.023	0.977
M81.48 Drug-induced osteoporosis (Other)	0.023	0.977
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.023	0.977
M81.46 Drug-induced osteoporosis (Lower leg)	0.023	0.977
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.023	0.977
M81.44 Drug-induced osteoporosis (Hand)	0.023	0.977
M81.43 Drug-induced osteoporosis (Forearm)	0.023	0.977
M81.42 Drug-induced osteoporosis (Upper arm)	0.023	0.977
M81.41 Drug-induced osteoporosis (Shoulder region)	0.023	0.977
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.023	0.977
H44 Disorders of globe	0.023	0.977
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.023	0.977
M84.06 Malunion of fracture (Lower leg)	0.022	0.977
H47 Other disorders of optic [2nd] nerve and visual pathways	0.022	0.978
S40-S49 Injuries to the shoulder and upper arm	0.022	0.978
H11 Other disorders of conjunctiva	0.022	0.978
H65 Nonsuppurative otitis media	0.022	0.978
M82.1 Osteoporosis in endocrine disorders	0.022	0.978
S22 Fracture of rib(s), sternum and thoracic spine	0.022	0.978
M84.9 Disorder of continuity of bone, unspecified	0.022	0.978
M84.8 Other disorders of continuity of bone	0.022	0.978
M84.4 Pathological fracture, not elsewhere classified	0.022	0.978
M84.3 Stress fracture, not elsewhere classified	0.022	0.978
M84.2 Delayed union of fracture	0.022	0.978
H57 Other disorders of eye and adnexa	0.022	0.978
S20 Superficial injury of thorax	0.022	0.978
Y52.3 Coronary vasodilators, not elsewhere classified	0.022	0.978
N48 Other disorders of penis	0.022	0.978
S00-S09 Injuries to the head	0.022	0.978
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.021	0.978
H65.3 Chronic mucoid otitis media	0.021	0.979
H43.8 Other disorders of vitreous body	0.021	0.979
W00-W19 Falls	0.021	0.979
M81.40 Drug-induced osteoporosis (Multiple sites)	0.021	0.979
# Top node	0.021	0.979
W25 Contact with sharp glass	0.021	0.979
H65.9 Nonsuppurative otitis media, unspecified	0.021	0.979
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.021	0.979
Y40 Systemic antibiotics	0.021	0.979
M85.8 Other specified disorders of bone density and structure	0.021	0.979
Q20-Q28 Congenital malformations of the circulatory system	0.021	0.979
Y60-Y69 Misadventures to patients during surgical and medical care	0.021	0.979
H55 Nystagmus and other irregular eye movements	0.021	0.979
H20 Iridocyclitis	0.021	0.979
W21 Striking against or struck by sports equipment	0.021	0.979
H53.0 Amblyopia ex anopsia	0.021	0.979
Y48 Anaesthetics and therapeutic gases	0.021	0.979
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.021	0.979
Y44 Agents primarily affecting blood constituents	0.021	0.979
Q60-Q64 Congenital malformations of the urinary system	0.021	0.979
N17-N19 Renal failure	0.021	0.979
Y47 Sedatives, hypnotics and antianxiety drugs	0.020	0.979
S27 Injury of other and unspecified intrathoracic organs	0.020	0.979
S40 Superficial injury of shoulder and upper arm	0.020	0.979
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.020	0.980
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.020	0.980
H65-H75 Diseases of middle ear and mastoid	0.020	0.980
H11.3 Conjunctival haemorrhage	0.020	0.980
H16 Keratitis	0.020	0.980
W50-W64 Exposure to animate mechanical forces	0.020	0.980
H43.3 Other vitreous opacities	0.020	0.980
W20 Struck by thrown, projected or falling object	0.020	0.980
Y54.4 Loop [high-ceiling] diuretics	0.020	0.980
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.020	0.980
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.020	0.980
Chapter XIV Diseases of the genitourinary system	0.020	0.980
Chapter VIII Diseases of the ear and mastoid process	0.020	0.980
M82.8 Osteoporosis in other diseases classified elsewhere	0.020	0.980
M82.0 Osteoporosis in multiple myelomatosis	0.020	0.980
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.020	0.980
T00-T07 Injuries involving multiple body regions	0.020	0.980
Y51 Drugs primarily affecting the autonomic nervous system	0.020	0.980
M84.09 Malunion of fracture (Site unspecified)	0.020	0.980
M84.08 Malunion of fracture (Other)	0.020	0.980
M84.07 Malunion of fracture (Ankle and foot)	0.020	0.980
M84.05 Malunion of fracture (Pelvic region and thigh)	0.020	0.980
M84.04 Malunion of fracture (Hand)	0.020	0.980
M84.02 Malunion of fracture (Upper arm)	0.020	0.980
M84.01 Malunion of fracture (Shoulder region)	0.020	0.980
M84.00 Malunion of fracture (Multiple sites)	0.020	0.980
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.020	0.980
Chapter I Certain infectious and parasitic diseases	0.020	0.980
T15-T19 Effects of foreign body entering through natural orifice	0.020	0.980
S70-S79 Injuries to the hip and thigh	0.020	0.980
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.020	0.980
N50.8 Other specified disorders of male genital organs	0.020	0.980
S20.2 Contusion of thorax	0.020	0.980
H53.4 Visual field defects	0.020	0.980
Y41 Other systemic anti-infectives and antiparasitics	0.020	0.980
N40-N51 Diseases of male genital organs	0.020	0.980
M85.0 Fibrous dysplasia (monostotic)	0.019	0.980
S50-S59 Injuries to the elbow and forearm	0.020	0.980
H46 Optic neuritis	0.020	0.980
M85.9 Disorder of bone density and structure, unspecified	0.019	0.980
M85.6 Other cyst of bone	0.019	0.980
M85.5 Aneurysmal bone cyst	0.019	0.980
M85.4 Solitary bone cyst	0.019	0.980
M85.3 Osteitis condensans	0.019	0.980
M85.2 Hyperostosis of skull	0.019	0.980
M85.1 Skeletal fluorosis	0.019	0.980
H17 Corneal scars and opacities	0.019	0.980
S05 Injury of eye and orbit	0.020	0.980
N50 Other disorders of male genital organs	0.020	0.980
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.019	0.981
X58-X59 Accidental exposure to other and unspecified factors	0.019	0.981
S22.4 Multiple fractures of ribs	0.019	0.981
H21 Other disorders of iris and ciliary body	0.019	0.981
H57.1 Ocular pain	0.019	0.981
T66-T78 Other and unspecified effects of external causes	0.019	0.981
S01.9 Open wound of head, part unspecified	0.019	0.981
Y00-Y09 Assault	0.019	0.981
H47.1 Papilloedema, unspecified	0.019	0.981
S01 Open wound of head	0.019	0.981
H30-H36 Disorders of choroid and retina	0.019	0.981
A30-A49 Other bacterial diseases	0.019	0.981
V40-V49 Car occupant injured in transport accident	0.019	0.981
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.019	0.981
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.019	0.981
H15 Disorders of sclera	0.019	0.981
Y59 Other and unspecified vaccines and biological substances	0.019	0.981
Y58 Bacterial vaccines	0.019	0.981
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.019	0.981
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.019	0.981
Y53 Agents primarily affecting the gastro-intestinal system	0.019	0.981
Y50 Central nervous system stimulants, not elsewhere classified	0.019	0.981
Y49 Psychotropic drugs, not elsewhere classified	0.019	0.981
Y46 Antiepileptics and anti-Parkinsonism drugs	0.019	0.981
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere	0.019	0.981
T20-T25 Burns and corrosions of external body surface, specified by site	0.019	0.981
M83.9 Adult osteomalacia, unspecified	0.018	0.981
M83.8 Other adult osteomalacia	0.018	0.981
M83.5 Other drug-induced osteomalacia in adults	0.018	0.981
M83.4 Aluminum bone disease	0.018	0.981
M83.3 Adult osteomalacia due to malnutrition	0.018	0.981
M83.2 Adult osteomalacia due to malabsorption	0.018	0.981
M83.1 Senile osteomalacia	0.018	0.981
M83.0 Puerperal osteomalacia	0.018	0.981
X50-X57 Overexertion, travel and privation	0.019	0.981
S46 Injury of muscle and tendon at shoulder and upper arm level	0.019	0.981
W22 Striking against or struck by other objects	0.019	0.981
S22.2 Fracture of sternum	0.018	0.981
H47.0 Disorders of optic nerve, not elsewhere classified	0.018	0.981
H44.2 Degenerative myopia	0.018	0.981
W25.9 Unspecified place	0.018	0.981
H13 Disorders of conjunctiva in diseases classified elsewhere	0.018	0.981
W44 Foreign body entering into or through eye or natural orifice	0.018	0.981
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.018	0.981
V10-V19 Pedal cyclist injured in transport accident	0.018	0.981
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.018	0.982
Y35-Y36 Legal intervention and operations of war	0.018	0.982
Y10-Y34 Event of undetermined intent	0.018	0.982
X85-X99 Assault	0.018	0.982
X30-X39 Exposure to forces of nature	0.018	0.982
X20-X29 Contact with venomous animals and plants	0.018	0.982
X10-X19 Contact with heat and hot substances	0.018	0.982
X00-X09 Exposure to smoke, fire and flames	0.018	0.982
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.018	0.982
W75-W84 Other accidental threats to breathing	0.018	0.982
W65-W74 Accidental drowning and submersion	0.018	0.982
V98-V99 Other and unspecified transport accidents	0.018	0.982
V95-V97 Air and space transport accidents	0.018	0.982
V90-V94 Water transport accidents	0.018	0.982
V70-V79 Bus occupant injured in transport accident	0.018	0.982
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.018	0.982
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.018	0.982
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.018	0.982
V01-V09 Pedestrian injured in transport accident	0.018	0.982
M80.0 Postmenopausal osteoporosis with pathological fracture	0.018	0.982
W29 Contact with other powered hand tools and household machinery	0.018	0.982
S27.0 Traumatic pneumothorax	0.018	0.982
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.018	0.982
M84.1 Nonunion of fracture [pseudarthrosis]	0.018	0.982
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.018	0.982
A49 Bacterial infection of unspecified site	0.018	0.982
S30 Superficial injury of abdomen, lower back and pelvis	0.018	0.982
H11.8 Other specified disorders of conjunctiva	0.018	0.982
W21.9 Unspecified place	0.018	0.982
W18 Other fall on same level	0.018	0.982
Y52.4 Angiotensin-converting-enzyme inhibitors	0.018	0.982
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.018	0.982
Y52.8 Antivaricose drugs, including sclerosing agents	0.018	0.982
Y52.7 Peripheral vasodilators	0.018	0.982
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.018	0.982
Y52.1 Calcium-channel blockers	0.018	0.982
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.018	0.982
Q61 Cystic kidney disease	0.018	0.982
V80-V89 Other land transport accidents	0.018	0.982
S41 Open wound of shoulder and upper arm	0.018	0.982
Y54.5 Other diuretics	0.018	0.982
N48.8 Other specified disorders of penis	0.018	0.982
W49 Exposure to other and unspecified inanimate mechanical forces	0.018	0.982
W46 Contact with hypodermic needle	0.018	0.982
W45 Foreign body or object entering through skin	0.018	0.982
W43 Exposure to vibration	0.018	0.982
W42 Exposure to noise	0.018	0.982
W41 Exposure to high-pressure jet	0.018	0.982
W40 Explosion of other materials	0.018	0.982
W39 Discharge of firework	0.018	0.982
W38 Explosion and rupture of other specified pressurised devices	0.018	0.982
W37 Explosion and rupture of pressurised tyre, pipe or hose	0.018	0.982
W36 Explosion and rupture of gas cylinder	0.018	0.982
W35 Explosion and rupture of boiler	0.018	0.982
W34 Discharge from other and unspecified firearms	0.018	0.982
W33 Rifle, shotgun and larger firearm discharge	0.018	0.982
W32 Handgun discharge	0.018	0.982
W31 Contact with other and unspecified machinery	0.018	0.982
W30 Contact with agricultural machinery	0.018	0.982
W28 Contact with powered lawn mower	0.018	0.982
W27 Contact with nonpowered hand tool	0.018	0.982
W26 Contact with knife, sword or dagger	0.018	0.982
W24 Contact with lifting and transmission devices, not elsewhere classified	0.018	0.982
W23 Caught, crushed, jammed or pinched in or between objects	0.018	0.982
S22.40 Multiple fractures of ribs (closed)	0.018	0.982
M80.8 Other osteoporosis with pathological fracture	0.018	0.982
M80.5 Idiopathic osteoporosis with pathological fracture	0.018	0.982
M80.4 Drug-induced osteoporosis with pathological fracture	0.018	0.982
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.018	0.982
M80.2 Osteoporosis of disuse with pathological fracture	0.018	0.982
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.018	0.982
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.018	0.982
S26 Injury of heart	0.018	0.982
S25 Injury of blood vessels of thorax	0.018	0.982
S24 Injury of nerves and spinal cord at thorax level	0.018	0.982
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.018	0.982
S21 Open wound of thorax	0.018	0.982
T33-T35 Frostbite	0.018	0.982
T26-T28 Burns and corrosions confined to eye and internal organs	0.018	0.982
H10 Conjunctivitis	0.018	0.982
Q38-Q45 Other congenital malformations of the digestive system	0.018	0.982
Q27 Other congenital malformations of peripheral vascular system	0.018	0.982
X60-X84 Intentional self-harm	0.018	0.982
H43.9 Disorder of vitreous body, unspecified	0.017	0.982
H43.2 Crystalline deposits in vitreous body	0.017	0.982
H43.0 Vitreous prolapse	0.017	0.982
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.017	0.982
S05.1 Contusion of eyeball and orbital tissues	0.017	0.982
S20.3 Other superficial injuries of front wall of thorax	0.017	0.982
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.017	0.982
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.017	0.983
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.017	0.983
B15-B19 Viral hepatitis	0.017	0.983
N25-N29 Other disorders of kidney and ureter	0.017	0.983
H44.0 Purulent endophthalmitis	0.017	0.983
Y40.0 Penicillins	0.017	0.983
W19 Unspecified fall	0.017	0.983
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.017	0.983
B25-B34 Other viral diseases	0.017	0.983
Q24 Other congenital malformations of heart	0.017	0.983
H18 Other disorders of cornea	0.017	0.983
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.017	0.983
A49.0 Staphylococcal infection, unspecified	0.017	0.983
S29 Other and unspecified injuries of thorax	0.017	0.983
S22.5 Flail chest	0.017	0.983
H11.9 Disorder of conjunctiva, unspecified	0.017	0.983
H11.1 Conjunctival degenerations and deposits	0.017	0.983
W20.0 Home	0.017	0.983
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.017	0.983
Q25 Congenital malformations of great arteries	0.017	0.983
Y44.5 Thrombolytic drugs	0.017	0.983
W11 Fall on and from ladder	0.017	0.983
T00 Superficial injuries involving multiple body regions	0.017	0.983
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.017	0.983
H66 Suppurative and unspecified otitis media	0.017	0.983
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.017	0.983
S00 Superficial injury of head	0.017	0.983
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.017	0.983
X40-X49 Accidental poisoning by and exposure to noxious substances	0.017	0.983
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.017	0.983
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.017	0.983
S10-S19 Injuries to the neck	0.017	0.983
S50 Superficial injury of forearm	0.017	0.983
Y48.4 Anaesthetic, unspecified	0.017	0.983
H20.0 Acute and subacute iridocyclitis	0.017	0.983
T14 Injury of unspecified body region	0.017	0.983
Y54.9 Mineral salts, not elsewhere classified	0.016	0.983
Y54.8 Agents affecting uric acid metabolism	0.016	0.983
Y54.7 Agents affecting calcification	0.016	0.983
Y54.6 Electrolytic, caloric and water-balance agents	0.016	0.983
Y54.2 Carbonic-anhydrase inhibitors	0.016	0.983
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.016	0.983
Y54.0 Mineralocorticoids	0.016	0.983
S90-S99 Injuries to the ankle and foot	0.017	0.983
W08 Fall involving other furniture	0.017	0.983
S70 Superficial injury of hip and thigh	0.017	0.983
N50.0 Atrophy of testis	0.017	0.983
Q60 Renal agenesis and other reduction defects of kidney	0.016	0.983
Y47.1 Benzodiazepines	0.016	0.983
T79-T79 Certain early complications of trauma	0.016	0.983
H44.9 Disorder of globe, unspecified	0.016	0.983
H44.8 Other disorders of globe	0.016	0.983
H44.7 Retained (old) intraocular foreign body, nonmagnetic	0.016	0.983
H44.6 Retained (old) intraocular foreign body, magnetic	0.016	0.983
H44.5 Degenerated conditions of globe	0.016	0.983
H44.4 Hypotony of eye	0.016	0.983
H44.3 Other degenerative disorders of globe	0.016	0.983
H44.1 Other endophthalmitis	0.016	0.983
H53.9 Visual disturbance, unspecified	0.016	0.984
N20-N23 Urolithiasis	0.016	0.984
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.016	0.984
Q35-Q37 Cleft lip and cleft palate	0.016	0.984
Q30-Q34 Congenital malformations of the respiratory system	0.016	0.984
H47.2 Optic atrophy	0.016	0.984
H47.7 Disorder of visual pathways, unspecified	0.016	0.984
H47.6 Disorders of visual cortex	0.016	0.984
H47.5 Disorders of other visual pathways	0.016	0.984
H47.4 Disorders of optic chiasm	0.016	0.984
N44 Torsion of testis	0.016	0.984
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.016	0.984
Q23 Congenital malformations of aortic and mitral valves	0.016	0.984
Q63 Other congenital malformations of kidney	0.016	0.984
S22.20 Fracture of sternum (closed)	0.016	0.984
V20-V29 Motorcycle rider injured in transport accident	0.016	0.984
H80-H83 Diseases of inner ear	0.016	0.984
S48 Traumatic amputation of shoulder and upper arm	0.016	0.984
S45 Injury of blood vessels at shoulder and upper arm level	0.016	0.984
S44 Injury of nerves at shoulder and upper arm level	0.016	0.984
S47 Crushing injury of shoulder and upper arm	0.016	0.984
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.016	0.984
N48.1 Balanoposthitis	0.016	0.984
H65.2 Chronic serous otitis media	0.016	0.984
H11.2 Conjunctival scars	0.016	0.984
Y40.1 Cefalosporins and other -lactam antibiotics	0.016	0.984
T17 Foreign body in respiratory tract	0.016	0.984
Q61.2 Polycystic kidney, adult type	0.016	0.984
H65.4 Other chronic nonsuppurative otitis media	0.016	0.984
H65.1 Other acute nonsuppurative otitis media	0.016	0.984
H65.0 Acute serous otitis media	0.016	0.984
S40.0 Contusion of shoulder and upper arm	0.016	0.984
B34 Viral infection of unspecified site	0.016	0.984
S52 Fracture of forearm	0.016	0.984
T78 Adverse effects, not elsewhere classified	0.016	0.984
H16.0 Corneal ulcer	0.016	0.984
B65-B83 Helminthiases	0.016	0.984
Y54.3 Benzothiadiazine derivatives	0.016	0.984
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods	0.016	0.984
N23 Unspecified renal colic	0.016	0.984
Y57 Other and unspecified drugs and medicaments	0.016	0.984
M82.19 Osteoporosis in endocrine disorders (Site unspecified)	0.016	0.984
M82.18 Osteoporosis in endocrine disorders (Other)	0.016	0.984
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)	0.016	0.984
M82.16 Osteoporosis in endocrine disorders (Lower leg)	0.016	0.984
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)	0.016	0.984
M82.14 Osteoporosis in endocrine disorders (Hand)	0.016	0.984
M82.13 Osteoporosis in endocrine disorders (Forearm)	0.016	0.984
M82.12 Osteoporosis in endocrine disorders (Upper arm)	0.016	0.984
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.016	0.984
S05.8 Other injuries of eye and orbit	0.016	0.984
S22.9 Fracture of bony thorax, part unspecified	0.016	0.984
S22.8 Fracture of other parts of bony thorax	0.016	0.984
H33 Retinal detachments and breaks	0.016	0.984
S60-S69 Injuries to the wrist and hand	0.016	0.984
M84.29 Delayed union of fracture (Site unspecified)	0.016	0.984
M84.28 Delayed union of fracture (Other)	0.016	0.984
M84.27 Delayed union of fracture (Ankle and foot)	0.016	0.984
M84.26 Delayed union of fracture (Lower leg)	0.016	0.984
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.016	0.984
M84.24 Delayed union of fracture (Hand)	0.016	0.984
M84.23 Delayed union of fracture (Forearm)	0.016	0.984
M84.22 Delayed union of fracture (Upper arm)	0.016	0.984
M84.21 Delayed union of fracture (Shoulder region)	0.016	0.984
M84.20 Delayed union of fracture (Multiple sites)	0.016	0.984
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.016	0.984
M84.38 Stress fracture, not elsewhere classified (Other)	0.016	0.984
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.016	0.984
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.016	0.984
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.016	0.984
M84.34 Stress fracture, not elsewhere classified (Hand)	0.016	0.984
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.016	0.984
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.016	0.984

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations