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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7349908
log Bayes Factor = 42.9684
Chromosome 6   position 29,397,521  (GRCh37) Explore rs7349908 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10.9 Without complications
0.000 0.001 0.999
E10.3 With ophthalmic complications
0.000 0.004 0.996
E10-E14 Diabetes mellitus
0.000 0.013 0.987
E10.1 With ketoacidosis
0.000 0.031 0.969
E13 Other specified diabetes mellitus
0.000 0.038 0.962
E10.2 With renal complications
0.000 0.046 0.954
E13.9 Without complications
0.000 0.057 0.943
E10.4 With neurological complications
0.000 0.083 0.917
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.095 0.905
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.102 0.898
E16 Other disorders of pancreatic internal secretion
0.000 0.106 0.894
E16.2 Hypoglycaemia, unspecified
0.000 0.113 0.887
E00-E07 Disorders of thyroid gland
0.000 0.170 0.830
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.174 0.826
E05.9 Thyrotoxicosis, unspecified
0.000 0.182 0.818
E10.6 With other specified complications
0.000 0.194 0.806
E10.0 With coma
0.000 0.215 0.785
E16.1 Other hypoglycaemia
0.000 0.230 0.770
E10.5 With peripheral circulatory complications
0.000 0.232 0.768
E14 Unspecified diabetes mellitus
0.000 0.242 0.758
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.261 0.739
E20-E35 Disorders of other endocrine glands
0.000 0.274 0.726
E05.8 Other thyrotoxicosis
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.292 0.708
E10.8 With unspecified complications
0.000 0.308 0.692
E13.8 With unspecified complications
0.000 0.311 0.689
E13.7 With multiple complications
0.000 0.311 0.689
E13.6 With other specified complications
0.000 0.311 0.689
E13.5 With peripheral circulatory complications
0.000 0.311 0.689
E13.4 With neurological complications
0.000 0.311 0.689
E13.3 With ophthalmic complications
0.000 0.311 0.689
E13.2 With renal complications
0.000 0.311 0.689
E13.1 With ketoacidosis
0.000 0.311 0.689
E13.0 With coma
0.000 0.311 0.689
E23 Hypofunction and other disorders of pituitary gland
0.000 0.338 0.662
E15 Nondiabetic hypoglycaemic coma
0.000 0.356 0.644
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.359 0.641
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.359 0.641
E16.4 Abnormal secretion of gastrin
0.000 0.359 0.641
E16.3 Increased secretion of glucagon
0.000 0.359 0.641
E50-E64 Other nutritional deficiencies
0.000 0.360 0.640
E24 Cushing's syndrome
0.000 0.371 0.629
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.380 0.619
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.383 0.617
E23.0 Hypopituitarism
0.000 0.397 0.603
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.405 0.595
E00 Congenital iodine-deficiency syndrome
0.000 0.405 0.595
E05.5 Thyroid crisis or storm
0.000 0.408 0.592
E05.4 Thyrotoxicosis factitia
0.000 0.408 0.592
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.408 0.592
E14.9 Without complications
0.000 0.417 0.583
E20 Hypoparathyroidism
0.000 0.418 0.582
E40-E46 Malnutrition
0.000 0.419 0.581
E11 Non-insulin-dependent diabetes mellitus
0.000 0.423 0.577
E14.2 Withrenal complications
0.000 0.423 0.576
E14.4 With neurological complications
0.000 0.429 0.571
E22 Hyperfunction of pituitary gland
0.000 0.433 0.567
E23.2 Diabetes insipidus
0.000 0.439 0.561
E14.8 With unspecified complications
0.000 0.444 0.556
E29 Testicular dysfunction
0.000 0.450 0.550
E14.1 With ketoacidosis
0.000 0.454 0.546
E14.7 With multiple complications
0.000 0.456 0.544
E14.6 With other specified complications
0.000 0.456 0.544
E14.5 With peripheral circulatory complications
0.000 0.456 0.544
E14.0 With coma
0.000 0.456 0.544
E24.9 Cushing's syndrome, unspecified
0.000 0.458 0.542
E55 Vitamin D deficiency
0.000 0.472 0.527
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.480 0.520
E32 Diseases of thymus
0.000 0.480 0.520
E30 Disorders of puberty, not elsewhere classified
0.000 0.480 0.520
E25 Adrenogenital disorders
0.000 0.480 0.520
E07 Other disorders of thyroid
0.000 0.489 0.511
E12.9 Without complications
0.000 0.492 0.507
E12.8 With unspecified complications
0.000 0.492 0.507
E12.7 With multiple complications
0.000 0.492 0.507
E12.6 With other specified complications
0.000 0.492 0.507
E12.5 With peripheral circulatory complications
0.000 0.492 0.507
E12.4 With neurological complications
0.000 0.492 0.507
E12.3 With ophthalmic complications
0.000 0.492 0.507
E12.2 With renal complications
0.000 0.492 0.507
E12.1 With ketoacidosis
0.000 0.492 0.507
E12.0 With coma
0.000 0.492 0.507
E11.2 With renal complications
0.000 0.494 0.506
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.503 0.497
E11.6 With other specified complications
0.000 0.510 0.490
E28 Ovarian dysfunction
0.000 0.511 0.489
E24.2 Drug-induced Cushing's syndrome
0.000 0.512 0.488
E23.7 Disorder of pituitary gland, unspecified
0.000 0.515 0.485
E20.9 Hypoparathyroidism, unspecified
0.000 0.521 0.479
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.525 0.474
E23.1 Drug-induced hypopituitarism
0.000 0.525 0.474
E56 Other vitamin deficiencies
0.000 0.530 0.470
E31 Polyglandular dysfunction
0.000 0.531 0.469
E14.3 With ophthalmic complications
0.000 0.533 0.467
E11.0 With coma
0.000 0.535 0.465
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.541 0.459
E63 Other nutritional deficiencies
0.000 0.541 0.459
E53 Deficiency of other B group vitamins
0.000 0.541 0.459
E51 Thiamine deficiency
0.000 0.541 0.459
E50 Vitamin A deficiency
0.000 0.541 0.459
E60 Dietary zinc deficiency
0.000 0.541 0.459
E59 Dietary selenium deficiency
0.000 0.541 0.459
E54 Ascorbic acid deficiency
0.000 0.541 0.459
E52 Niacin deficiency [pellagra]
0.000 0.541 0.459
E06 Thyroiditis
0.000 0.542 0.457
E22.0 Acromegaly and pituitary gigantism
0.000 0.543 0.457
E24.8 Other Cushing's syndrome
0.000 0.549 0.451
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.549 0.451
E24.3 Ectopic ACTH syndrome
0.000 0.549 0.451
E24.1 Nelson's syndrome
0.000 0.549 0.451
E24.0 Pituitary-dependent Cushing's disease
0.000 0.549 0.451
E55.9 Vitamin D deficiency, unspecified
0.000 0.553 0.447
E27 Other disorders of adrenal gland
0.000 0.564 0.436
E34 Other endocrine disorders
0.000 0.567 0.432
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.573 0.426
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.573 0.426
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.573 0.426
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.573 0.426
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.573 0.426
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.573 0.426
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.573 0.426
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.573 0.426
E29.1 Testicular hypofunction
0.000 0.575 0.425
E11.8 With unspecified complications
0.000 0.578 0.422
E11.1 With ketoacidosis
0.000 0.579 0.420
E26 Hyperaldosteronism
0.000 0.580 0.419
E20.8 Other hypoparathyroidism
0.000 0.582 0.417
E20.1 Pseudohypoparathyroidism
0.000 0.582 0.417
E20.0 Idiopathic hypoparathyroidism
0.000 0.582 0.417
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.583 0.416
E45 Retarded development following protein-energy malnutrition
0.000 0.583 0.416
E43 Unspecified severe protein-energy malnutrition
0.000 0.583 0.416
E42 Marasmic kwashiorkor
0.000 0.583 0.416
E41 Nutritional marasmus
0.000 0.583 0.416
E40 Kwashiorkor
0.000 0.583 0.416
E11.7 With multiple complications
0.000 0.586 0.414
E53.9 Vitamin B deficiency, unspecified
0.000 0.593 0.407
E22.1 Hyperprolactinaemia
0.000 0.593 0.406
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.594 0.406
E22.8 Other hyperfunction of pituitary gland
0.000 0.594 0.406
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.601 0.399
E58 Dietary calcium deficiency
0.000 0.601 0.399
E29.9 Testicular dysfunction, unspecified
0.000 0.605 0.395
E29.8 Other testicular dysfunction
0.000 0.605 0.395
E29.0 Testicular hyperfunction
0.000 0.605 0.395
E61 Deficiency of other nutrient elements
0.000 0.606 0.394
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.615 0.384
E03 Other hypothyroidism
0.000 0.620 0.380
E11.5 With peripheral circulatory complications
0.000 0.621 0.379
E07.8 Other specified disorders of thyroid
0.000 0.621 0.379
E55.0 Rickets, active
0.000 0.622 0.378
E23.6 Other disorders of pituitary gland
0.000 0.622 0.377
E28.3 Primary ovarian failure
0.000 0.626 0.374
E25.9 Adrenogenital disorder, unspecified
0.000 0.627 0.373
E25.8 Other adrenogenital disorders
0.000 0.627 0.373
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.627 0.373
E30.9 Disorder of puberty, unspecified
0.000 0.627 0.373
E30.8 Other disorders of puberty
0.000 0.627 0.373
E30.1 Precocious puberty
0.000 0.627 0.373
E30.0 Delayed puberty
0.000 0.627 0.373
E32.9 Disease of thymus, unspecified
0.000 0.627 0.373
E32.8 Other diseases of thymus
0.000 0.627 0.373
E32.1 Abscess of thymus
0.000 0.627 0.373
E32.0 Persistent hyperplasia of thymus
0.000 0.627 0.373
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.627 0.373
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.627 0.373
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.627 0.373
E06.9 Thyroiditis, unspecified
0.000 0.630 0.370
E07.1 Dyshormogenetic goitre
0.000 0.633 0.366
E07.0 Hypersecretion of calcitonin
0.000 0.633 0.366
E27.1 Primary adrenocortical insufficiency
0.000 0.637 0.363
K90 Intestinal malabsorption
0.000 0.644 0.356
E28.9 Ovarian dysfunction, unspecified
0.000 0.649 0.351
E28.8 Other ovarian dysfunction
0.000 0.649 0.351
E28.1 Androgen excess
0.000 0.649 0.351
E28.0 Oestrogen excess
0.000 0.649 0.351
E56.1 Deficiency of vitamin K
0.000 0.652 0.348
E46 Unspecified protein-energy malnutrition
0.000 0.652 0.348
E56.9 Vitamin deficiency, unspecified
0.000 0.663 0.337
E56.8 Deficiency of other vitamins
0.000 0.663 0.337
E56.0 Deficiency of vitamin E
0.000 0.663 0.337
E31.9 Polyglandular dysfunction, unspecified
0.000 0.664 0.336
E31.8 Other polyglandular dysfunction
0.000 0.664 0.336
E31.1 Polyglandular hyperfunction
0.000 0.664 0.336
E83 Disorders of mineral metabolism
0.331 0.669 0.000
E50.9 Vitamin A deficiency, unspecified
0.000 0.671 0.329
E50.8 Other manifestations of vitamin A deficiency
0.000 0.671 0.329
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.671 0.329
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.671 0.329
E50.5 Vitamin A deficiency with night blindness
0.000 0.671 0.329
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.671 0.329
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.671 0.329
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.671 0.329
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.671 0.329
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.671 0.329
E51.9 Thiamine deficiency, unspecified
0.000 0.671 0.329
E51.8 Other manifestations of thiamine deficiency
0.000 0.671 0.329
E51.2 Wernicke's encephalopathy
0.000 0.671 0.329
E51.1 Beriberi
0.000 0.671 0.329
E53.1 Pyridoxine deficiency
0.000 0.671 0.329
E53.0 Riboflavin deficiency
0.000 0.671 0.329
E63.9 Nutritional deficiency, unspecified
0.000 0.671 0.329
E63.8 Other specified nutritional deficiencies
0.000 0.671 0.329
E63.1 Imbalance of constituents of food intake
0.000 0.671 0.329
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.671 0.329
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.671 0.329
E64.8 Sequelae of other nutritional deficiencies
0.000 0.671 0.329
E64.3 Sequelae of rickets
0.000 0.671 0.329
E64.2 Sequelae of vitamin C deficiency
0.000 0.671 0.329
E64.1 Sequelae of vitamin A deficiency
0.000 0.671 0.329
E64.0 Sequelae of protein-energy malnutrition
0.000 0.671 0.329
E06.4 Drug-induced thyroiditis
0.000 0.672 0.328
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.672 0.328
E06.1 Subacute thyroiditis
0.000 0.672 0.328
E06.0 Acute thyroiditis
0.000 0.672 0.328
E34.8 Other specified endocrine disorders
0.000 0.679 0.321
E11.4 With neurological complications
0.000 0.684 0.316
E27.5 Adrenomedullary hyperfunction
0.000 0.688 0.312
E27.0 Other adrenocortical overactivity
0.000 0.688 0.312
E34.5 Androgen resistance syndrome
0.000 0.690 0.310
E34.4 Constitutional tall stature
0.000 0.690 0.310
E34.3 Short stature, not elsewhere classified
0.000 0.690 0.310
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.690 0.310
E34.1 Other hypersecretion of intestinal hormones
0.000 0.690 0.310
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.690 0.310
E65-E68 Obesity and other hyperalimentation
0.000 0.691 0.309
E03.8 Other specified hypothyroidism
0.000 0.699 0.301
E26.9 Hyperaldosteronism, unspecified
0.000 0.699 0.301
E26.8 Other hyperaldosteronism
0.000 0.699 0.301
E26.1 Secondary hyperaldosteronism
0.000 0.699 0.301
E27.8 Other specified disorders of adrenal gland
0.000 0.699 0.301
E44.1 Mild protein-energy malnutrition
0.000 0.701 0.299
E44.0 Moderate protein-energy malnutrition
0.000 0.701 0.299
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.706 0.294
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.710 0.290
E34.9 Endocrine disorder, unspecified
0.000 0.710 0.290
E28.2 Polycystic ovarian syndrome
0.000 0.714 0.286
E27.9 Disorder of adrenal gland, unspecified
0.000 0.715 0.285
E31.0 Autoimmune polyglandular failure
0.000 0.715 0.284
E61.9 Deficiency of nutrient element, unspecified
0.000 0.717 0.282
E61.8 Deficiency of other specified nutrient elements
0.000 0.717 0.282
E61.7 Deficiency of multiple nutrient elements
0.000 0.717 0.282
E61.6 Vanadium deficiency
0.000 0.717 0.282
E61.5 Molybdenum deficiency
0.000 0.717 0.282
E61.4 Chromium deficiency
0.000 0.717 0.282
E61.3 Manganese deficiency
0.000 0.717 0.282
E61.0 Copper deficiency
0.000 0.717 0.282
E03.5 Myxoedema coma
0.000 0.727 0.273
E03.4 Atrophy of thyroid (acquired)
0.000 0.727 0.273
E03.3 Postinfectious hypothyroidism
0.000 0.727 0.273
E03.1 Congenital hypothyroidism without goitre
0.000 0.727 0.273
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.727 0.273
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.728 0.272
E83.3 Disorders of phosphorus metabolism
0.269 0.731 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.739 0.261
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.743 0.257
E06.5 Other chronic thyroiditis
0.000 0.743 0.256
K90.3 Pancreatic steatorrhoea
0.000 0.744 0.255
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.744 0.255
K90.1 Tropical sprue
0.000 0.744 0.255
E61.2 Magnesium deficiency
0.000 0.745 0.255
E61.1 Iron deficiency
0.000 0.747 0.253
E83.4 Disorders of magnesium metabolism
0.240 0.760 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.237 0.763 0.000
E83.8 Other disorders of mineral metabolism
0.237 0.763 0.000
E83.2 Disorders of zinc metabolism
0.237 0.763 0.000
E83.0 Disorders of copper metabolism
0.237 0.763 0.000
K90.8 Other intestinal malabsorption
0.000 0.763 0.237
E34.0 Carcinoid syndrome
0.000 0.765 0.234
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.774 0.226
E67 Other hyperalimentation
0.000 0.778 0.222
E68 Sequelae of hyperalimentation
0.000 0.778 0.222
K90.9 Intestinal malabsorption, unspecified
0.000 0.783 0.217
E27.2 Addisonian crisis
0.000 0.788 0.212
E21.4 Other specified disorders of parathyroid gland
0.000 0.792 0.208
E21.2 Other hyperparathyroidism
0.000 0.792 0.208
E06.3 Autoimmune thyroiditis
0.000 0.796 0.203
E26.0 Primary hyperaldosteronism
0.001 0.800 0.200
E04 Other non-toxic goitre
0.001 0.809 0.190
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.814 0.186
E21.3 Hyperparathyroidism, unspecified
0.000 0.819 0.180
E65 Localised adiposity
0.000 0.826 0.174
E11.9 Without complications
0.000 0.826 0.174
E04.9 Non-toxic goitre, unspecified
0.000 0.832 0.168
E67.8 Other specified hyperalimentation
0.000 0.841 0.159
E67.3 Hypervitaminosis D
0.000 0.841 0.159
E67.2 Megavitamin-B6 syndrome
0.000 0.841 0.159
E67.1 Hypercarotenaemia
0.000 0.841 0.159
E67.0 Hypervitaminosis A
0.000 0.841 0.159
E11.3 With ophthalmic complications
0.000 0.845 0.155
E04.8 Other specified non-toxic goitre
0.001 0.863 0.136
E53.8 Deficiency of other specified B group vitamins
0.000 0.867 0.133
E83.5 Disorders of calcium metabolism
0.114 0.886 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.106 0.894 0.000
E04.0 Non-toxic diffuse goitre
0.001 0.918 0.081
K51 Ulcerative colitis
0.066 0.934 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.063 0.937 0.000
K51.4 Pseudopolyposis of colon
0.062 0.938 0.000
K51.9 Ulcerative colitis, unspecified
0.061 0.939 0.000
K51.2 Ulcerative (chronic) proctitis
0.058 0.942 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.056 0.944 0.000
E21.0 Primary hyperparathyroidism
0.000 0.945 0.055
K51.5 Mucosal proctocolitis
0.051 0.949 0.000
I83 Varicose veins of lower extremities
0.048 0.952 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.047 0.953 0.000
K51.8 Other ulcerative colitis
0.040 0.960 0.000
I83.1 Varicose veins of lower extremities with inflammation
0.040 0.960 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.037 0.963 0.000
E66 Obesity
0.000 0.968 0.032
K50-K52 Noninfective enteritis and colitis
0.028 0.972 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.026 0.974 0.000
K50 Crohn's disease [regional enteritis]
0.026 0.974 0.000
K50.9 Crohn's disease, unspecified
0.024 0.976 0.000
E04.1 Non-toxic single thyroid nodule
0.001 0.976 0.023
E66.1 Drug-induced obesity
0.000 0.976 0.023
K50.0 Crohn's disease of small intestine
0.022 0.978 0.000
K90-K93 Other diseases of the digestive system
0.000 0.979 0.021
V18.0 Driver injured in nontraffic accident
0.021 0.979 0.000
E66.0 Obesity due to excess calories
0.000 0.980 0.020
C43.5 Malignant melanoma of trunk
0.000 0.981 0.019
K50.1 Crohn's disease of large intestine
0.018 0.982 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.983 0.017
K50.8 Other Crohn's disease
0.016 0.984 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.984 0.015
E04.2 Non-toxic multinodular goitre
0.001 0.985 0.014
H54.0 Blindness, both eyes
0.000 0.985 0.015
J38.4 Oedema of larynx
0.015 0.985 0.000
A08.4 Viral intestinal infection, unspecified
0.000 0.985 0.015
J38.7 Other diseases of larynx
0.014 0.986 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.014 0.986 0.000
H54 Blindness and low vision
0.000 0.987 0.013
J38.3 Other diseases of vocal cords
0.013 0.987 0.000
H54.9 Unspecified visual impairment (binocular)
0.000 0.987 0.013
F45.8 Other somatoform disorders
0.000 0.987 0.013
M79.09 Rheumatism, unspecified (Site unspecified)
0.000 0.988 0.012
E70-E90 Metabolic disorders
0.003 0.988 0.009
J38.2 Nodules of vocal cords
0.012 0.988 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.011 0.988 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.989 0.011
K93.1 Megacolon in Chagas' disease
0.000 0.989 0.011
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.989 0.011
J38.5 Laryngeal spasm
0.011 0.989 0.000
H54.6 Unqualified visual loss, one eye
0.000 0.989 0.011
H54.5 Low vision, one eye
0.000 0.989 0.011
H54.7 Unspecified visual loss
0.000 0.990 0.010
H54.3 Unqualified visual loss, both eyes
0.000 0.990 0.009
E73 Lactose intolerance
0.002 0.991 0.008
C43 Malignant melanoma of skin
0.000 0.991 0.009
H54.2 Low vision, both eyes
0.000 0.991 0.009
E79 Disorders of purine and pyrimidine metabolism
0.002 0.991 0.007
E74 Other disorders of carbohydrate metabolism
0.002 0.991 0.007
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.002 0.991 0.007
E66.8 Other obesity
0.000 0.991 0.009
V18.5 Passenger injured in traffic accident
0.009 0.991 0.000
E77 Disorders of glycoprotein metabolism
0.003 0.991 0.006
E76 Disorders of glycosaminoglycan metabolism
0.003 0.991 0.006
E72 Other disorders of amino-acid metabolism
0.003 0.991 0.006
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.003 0.991 0.006
E70 Disorders of aromatic amino-acid metabolism
0.003 0.991 0.006
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.003 0.991 0.006
J38.1 Polyp of vocal cord and larynx
0.009 0.991 0.000
V18.9 Unspecified pedal cyclist injured in traffic accident
0.008 0.991 0.000
V18.4 Driver injured in traffic accident
0.008 0.991 0.000
E84 Cystic fibrosis
0.003 0.991 0.006
V18.1 Passenger injured in nontraffic accident
0.008 0.991 0.000
J38.6 Stenosis of larynx
0.008 0.992 0.000
M79.0 Rheumatism, unspecified
0.000 0.992 0.008
T85.4 Mechanical complication of breast prosthesis and implant
0.000 0.992 0.008
H54.4 Blindness, one eye
0.000 0.992 0.008
H54.1 Blindness, one eye, low vision, other eye
0.000 0.992 0.008
C43.3 Malignant melanoma of other and unspecified parts of face
0.000 0.992 0.008
J35.8 Other chronic diseases of tonsils and adenoids
0.008 0.992 0.000
C43.6 Malignant melanoma of upper limb, including shoulder
0.000 0.992 0.008
E85 Amyloidosis
0.002 0.992 0.006
V18.2 Unspecified pedal cyclist injured in nontraffic accident
0.008 0.992 0.000
M79.08 Rheumatism, unspecified (Other)
0.000 0.992 0.008
V18.3 Person injured while boarding or alighting
0.008 0.992 0.000
N18.4 Chronic kidney disease, stage 4
0.000 0.992 0.008
E73.9 Lactose intolerance, unspecified
0.001 0.992 0.007
F45 Somatoform disorders
0.000 0.993 0.007
C43.4 Malignant melanoma of scalp and neck
0.000 0.993 0.007
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.007 0.993 0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.001 0.993 0.006
E73.8 Other lactose intolerance
0.001 0.993 0.006
E73.1 Secondary lactase deficiency
0.001 0.993 0.006
E73.0 Congenital lactase deficiency
0.001 0.993 0.006
S62.30 Fracture of other metacarpal bone (closed)
0.000 0.993 0.007
C43.9 Malignant melanoma of skin, unspecified
0.000 0.993 0.007
E74.3 Other disorders of intestinal carbohydrate absorption
0.001 0.993 0.006
M79.00 Rheumatism, unspecified (Multiple sites)
0.000 0.993 0.007
N08.3 Glomerular disorders in diabetes mellitus
0.000 0.993 0.007
E75.5 Other lipid storage disorders
0.002 0.993 0.005
C43.8 Overlapping malignant melanoma of skin
0.000 0.993 0.007
C43.0 Malignant melanoma of lip
0.000 0.993 0.007
D47.4 Osteomyelofibrosis
0.000 0.993 0.007
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.002 0.993 0.005
E79.8 Other disorders of purine and pyrimidine metabolism
0.002 0.993 0.005
E79.1 Lesch-Nyhan syndrome
0.002 0.993 0.005
E74.9 Disorder of carbohydrate metabolism, unspecified
0.002 0.993 0.005
E74.8 Other specified disorders of carbohydrate metabolism
0.002 0.993 0.005
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.002 0.993 0.005
E74.2 Disorders of galactose metabolism
0.002 0.993 0.005
E74.1 Disorders of fructose metabolism
0.002 0.993 0.005
E74.0 Glycogen storage disease
0.002 0.993 0.005
K04.5 Chronic apical periodontitis
0.007 0.993 0.000
E75.6 Lipid storage disorder, unspecified
0.002 0.993 0.005
E75.4 Neuronal ceroid lipofuscinosis
0.002 0.993 0.005
E75.3 Sphingolipidosis, unspecified
0.002 0.993 0.005
E75.2 Other sphingolipidosis
0.002 0.993 0.005
E75.1 Other gangliosidosis
0.002 0.993 0.005
E75.0 GM2 gangliosidosis
0.002 0.993 0.005
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.002 0.993 0.005
E70.8 Other disorders of aromatic amino-acid metabolism
0.002 0.993 0.005
E70.3 Albinism
0.002 0.993 0.005
E70.2 Disorders of tyrosine metabolism
0.002 0.993 0.005
E70.1 Other hyperphenylalaninaemias
0.002 0.993 0.005
E70.0 Classical phenylketonuria
0.002 0.993 0.005
E71.3 Disorders of fatty-acid metabolism
0.002 0.993 0.005
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.002 0.993 0.005
E71.1 Other disorders of branched-chain amino-acid metabolism
0.002 0.993 0.005
E71.0 Maple-syrup-urine disease
0.002 0.993 0.005
E72.9 Disorder of amino-acid metabolism, unspecified
0.002 0.993 0.005
E72.8 Other specified disorders of amino-acid metabolism
0.002 0.993 0.005
E72.5 Disorders of glycine metabolism
0.002 0.993 0.005
E72.4 Disorders of ornithine metabolism
0.002 0.993 0.005
E72.3 Disorders of lysine and hydroxylysine metabolism
0.002 0.993 0.005
E72.2 Disorders of urea cycle metabolism
0.002 0.993 0.005
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.002 0.993 0.005
E72.0 Disorders of amino-acid transport
0.002 0.993 0.005
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.002 0.993 0.005
E76.8 Other disorders of glucosaminoglycan metabolism
0.002 0.993 0.005
E76.3 Mucopolysaccharidosis, unspecified
0.002 0.993 0.005
E76.2 Other mucopolysaccharidoses
0.002 0.993 0.005
E76.1 Mucopolysaccharidosis, type II
0.002 0.993 0.005
E76.0 Mucopolysaccharidosis, type I
0.002 0.993 0.005
E77.9 Disorder of glycoprotein metabolism, unspecified
0.002 0.993 0.005
E77.8 Other disorders of glycoprotein metabolism
0.002 0.993 0.005
E77.1 Defects in glycoprotein degradation
0.002 0.993 0.005
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.002 0.993 0.005
D47.2 Monoclonal gammopathy
0.000 0.993 0.007
M79.01 Rheumatism, unspecified (Shoulder region)
0.000 0.994 0.006
V18.49 Pedal cyclist injured in noncollision transport accident; driver injured in traffic accident ; during unspecified activity
0.006 0.994 0.000
V18.99 Pedal cyclist injured in noncollision transport accident; unspecified pedal cyclist injured in traffic accident; during unspecified activity
0.006 0.994 0.000
C50.8 Overlapping lesion of breast
0.000 0.994 0.006
E84.8 Cystic fibrosis with other manifestations
0.002 0.994 0.004
E84.1 Cystic fibrosis with intestinal manifestations
0.002 0.994 0.004
E84.0 Cystic fibrosis with pulmonary manifestations
0.002 0.994 0.004
E88 Other metabolic disorders
0.002 0.994 0.004
M79.07 Rheumatism, unspecified (Ankle and foot)
0.000 0.994 0.006
M79.05 Rheumatism, unspecified (Pelvic region and thigh)
0.000 0.994 0.006
M79.04 Rheumatism, unspecified (Hand)
0.000 0.994 0.006
M79.03 Rheumatism, unspecified (Forearm)
0.000 0.994 0.006
M79.02 Rheumatism, unspecified (Upper arm)
0.000 0.994 0.006
F45.9 Somatoform disorder, unspecified
0.000 0.994 0.006
C43.1 Malignant melanoma of eyelid, including canthus
0.000 0.994 0.006
D47.3 Essential (haemorrhagic) thrombocythaemia
0.000 0.994 0.006
E84.9 Cystic fibrosis, unspecified
0.002 0.994 0.004
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.000 0.994 0.006
E85.8 Other amyloidosis
0.002 0.994 0.005
E85.2 Heredofamilial amyloidosis, unspecified
0.002 0.994 0.005
E85.1 Neuropathic heredofamilial amyloidosis
0.002 0.994 0.005
E85.0 Nonneuropathic heredofamilial amyloidosis
0.002 0.994 0.005
E85.4 Organ-limited amyloidosis
0.001 0.994 0.005
F45.0 Somatisation disorder
0.000 0.994 0.006
E85.3 Secondary systemic amyloidosis
0.001 0.994 0.005
V10-V19 Pedal cyclist injured in transport accident
0.006 0.994 0.000
F45.2 Hypochondriacal disorder
0.000 0.994 0.006
S42.10 Fracture of scapula (closed)
0.000 0.994 0.006
C50.3 Lower-inner quadrant of breast
0.000 0.994 0.006
E80 Disorders of porphyrin and bilirubin metabolism
0.003 0.994 0.003
C77.3 Axillary and upper limb lymph nodes
0.000 0.994 0.006
F45.1 Undifferentiated somatoform disorder
0.000 0.994 0.005
F45.3 Somatoform autonomic dysfunction
0.000 0.995 0.005
F45.4 Persistent somatoform pain disorder
0.000 0.995 0.005
E85.9 Amyloidosis, unspecified
0.001 0.995 0.004
F41.1 Generalised anxiety disorder
0.000 0.995 0.005
N48.4 Impotence of organic origin
0.005 0.995 0.000
M79.06 Rheumatism, unspecified (Lower leg)
0.000 0.995 0.005
J38.0 Paralysis of vocal cords and larynx
0.005 0.995 0.000
N18.5 Chronic kidney disease, stage 5
0.000 0.995 0.005
V19 Pedal cyclist injured in other and unspecified transport accidents
0.005 0.995 0.000
J35.2 Hypertrophy of adenoids
0.005 0.995 0.000
E88.1 Lipodystrophy, not elsewhere classified
0.001 0.995 0.004
A08 Viral and other specified intestinal infections
0.000 0.995 0.005
N08 Glomerular disorders in diseases classified elsewhere
0.000 0.995 0.005
E88.9 Metabolic disorder, unspecified
0.002 0.995 0.003
N08.5 Glomerular disorders in systemic connective tissue disorders
0.000 0.995 0.005
V10 Pedal cyclist injured in collision with pedestrian or animal
0.005 0.995 0.000
C43.2 Malignant melanoma of ear and external auricular canal
0.000 0.995 0.005
V17 Pedal cyclist injured in collision with fixed or stationary object
0.005 0.995 0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
0.000 0.995 0.005
E88.2 Lipomatosis, not elsewhere classified
0.001 0.995 0.003
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.000 0.995 0.005
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]
0.000 0.995 0.005
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour
0.000 0.995 0.005
C50 Malignant neoplasm of breast
0.000 0.995 0.005

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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