TreeWAS – Variant ID: rs7350481

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E78.0 Pure hypercholesterolaemia	0.000	0.000	1.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.066	0.934
E78.5 Hyperlipidaemia, unspecified	0.000	0.104	0.896
E78.2 Mixed hyperlipidaemia	0.000	0.184	0.816
E78.1 Pure hyperglyceridaemia	0.000	0.240	0.760
E78.4 Other hyperlipidaemia	0.000	0.271	0.729
E78.6 Lipoprotein deficiency	0.000	0.304	0.696
E78.3 Hyperchylomicronaemia	0.000	0.335	0.665
E78.8 Other disorders of lipoprotein metabolism	0.000	0.359	0.641
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.476	0.524
G43.9 Migraine, unspecified	0.028	0.972	0.000
I34.1 Mitral (valve) prolapse	0.000	0.983	0.017
I34.0 Mitral (valve) insufficiency	0.000	0.983	0.017
I34 Nonrheumatic mitral valve disorders	0.000	0.983	0.017
G43 Migraine	0.016	0.984	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.000	0.986	0.014
I34.8 Other nonrheumatic mitral valve disorders	0.000	0.986	0.014
G43.1 Migraine with aura [classical migraine]	0.013	0.987	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.000	0.987	0.013
G43.0 Migraine without aura [common migraine]	0.013	0.987	0.000
G43.2 Status migrainosus	0.012	0.988	0.000
G43.3 Complicated migraine	0.011	0.989	0.000
Z86.1 Personal history of infectious and parasitic diseases	0.000	0.989	0.011
G43.8 Other migraine	0.010	0.989	0.000
E70-E90 Metabolic disorders	0.000	0.990	0.010
O02.1 Missed abortion	0.008	0.992	0.000
E21.0 Primary hyperparathyroidism	0.000	0.992	0.008
O00.1 Tubal pregnancy	0.008	0.992	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.992	0.008
E84 Cystic fibrosis	0.000	0.992	0.007
E72 Other disorders of amino-acid metabolism	0.000	0.992	0.007
E28.2 Polycystic ovarian syndrome	0.000	0.992	0.008
O00 Ectopic pregnancy	0.007	0.993	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.993	0.007
E20-E35 Disorders of other endocrine glands	0.000	0.993	0.007
E76 Disorders of glycosaminoglycan metabolism	0.000	0.993	0.007
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.993	0.007
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.993	0.007
S92.00 Fracture of calcaneus (closed)	0.000	0.993	0.007
E28 Ovarian dysfunction	0.000	0.993	0.007
E77 Disorders of glycoprotein metabolism	0.000	0.993	0.007
O02 Other abnormal products of conception	0.007	0.993	0.000
E70 Disorders of aromatic amino-acid metabolism	0.000	0.993	0.007
E79 Disorders of purine and pyrimidine metabolism	0.000	0.993	0.007
E88 Other metabolic disorders	0.000	0.993	0.007
E74 Other disorders of carbohydrate metabolism	0.000	0.993	0.007
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.993	0.007
S92.30 Fracture of metatarsal bone (closed)	0.000	0.993	0.007
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.993	0.007
E85 Amyloidosis	0.000	0.993	0.007
E73 Lactose intolerance	0.000	0.993	0.007
O00-O08 Pregnancy with abortive outcome	0.007	0.993	0.000
S92.0 Fracture of calcaneus	0.000	0.993	0.007
S92.3 Fracture of metatarsal bone	0.000	0.994	0.006
S92 Fracture of foot, except ankle	0.000	0.994	0.006
O00.9 Ectopic pregnancy, unspecified	0.006	0.994	0.000
E23 Hypofunction and other disorders of pituitary gland	0.000	0.994	0.006
E21.4 Other specified disorders of parathyroid gland	0.000	0.994	0.006
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.994	0.006
E22 Hyperfunction of pituitary gland	0.000	0.994	0.006
O04 Medical abortion	0.006	0.994	0.000
E84.9 Cystic fibrosis, unspecified	0.000	0.994	0.006
E80.4 Gilbert's syndrome	0.000	0.994	0.006
E72.0 Disorders of amino-acid transport	0.000	0.994	0.006
E20 Hypoparathyroidism	0.000	0.994	0.006
E21.2 Other hyperparathyroidism	0.000	0.994	0.006
E80.6 Other disorders of bilirubin metabolism	0.000	0.994	0.006
Z45.8 Adjustment and management of other implanted devices	0.000	0.994	0.006
E29 Testicular dysfunction	0.000	0.994	0.006
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.994	0.006
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.994	0.006
E84.8 Cystic fibrosis with other manifestations	0.000	0.994	0.006
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.994	0.006
E26 Hyperaldosteronism	0.000	0.994	0.006
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.994	0.005
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.994	0.005
E72.5 Disorders of glycine metabolism	0.000	0.994	0.005
E72.4 Disorders of ornithine metabolism	0.000	0.994	0.005
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.994	0.005
E72.2 Disorders of urea cycle metabolism	0.000	0.994	0.005
O04.9 Complete or unspecified, without complication	0.006	0.994	0.000
E21.3 Hyperparathyroidism, unspecified	0.000	0.994	0.006
E88.2 Lipomatosis, not elsewhere classified	0.000	0.994	0.006
O00.8 Other ectopic pregnancy	0.005	0.994	0.000
O00.2 Ovarian pregnancy	0.005	0.994	0.000
O00.0 Abdominal pregnancy	0.005	0.994	0.000
E80.5 Crigler-Najjar syndrome	0.000	0.994	0.005
E80.3 Defects of catalase and peroxydase	0.000	0.994	0.005
E80.0 Hereditary erythropoietic porphyria	0.000	0.994	0.005
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.994	0.005
E30 Disorders of puberty, not elsewhere classified	0.000	0.994	0.005
E25 Adrenogenital disorders	0.000	0.994	0.005
E71.3 Disorders of fatty-acid metabolism	0.000	0.994	0.005
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.994	0.005
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.994	0.005
E71.0 Maple-syrup-urine disease	0.000	0.994	0.005
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.994	0.005
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.994	0.005
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.994	0.005
E76.2 Other mucopolysaccharidoses	0.000	0.994	0.005
E76.1 Mucopolysaccharidosis, type II	0.000	0.994	0.005
E76.0 Mucopolysaccharidosis, type I	0.000	0.994	0.005
S92.2 Fracture of other tarsal bone(s)	0.000	0.994	0.005
E31 Polyglandular dysfunction	0.000	0.994	0.005
E28.9 Ovarian dysfunction, unspecified	0.000	0.994	0.005
E28.8 Other ovarian dysfunction	0.000	0.994	0.005
E28.1 Androgen excess	0.000	0.994	0.005
E28.0 Oestrogen excess	0.000	0.994	0.005
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.995	0.005
E77.1 Defects in glycoprotein degradation	0.000	0.995	0.005
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.995	0.005
E34 Other endocrine disorders	0.000	0.995	0.005
E80.1 Porphyria cutanea tarda	0.000	0.995	0.005
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.995	0.005
O02.8 Other specified abnormal products of conception	0.005	0.995	0.000
O08 Complications following abortion and ectopic and molar pregnancy	0.005	0.995	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.995	0.005
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.995	0.005
E70.2 Disorders of tyrosine metabolism	0.000	0.995	0.005
E70.1 Other hyperphenylalaninaemias	0.000	0.995	0.005
E70.0 Classical phenylketonuria	0.000	0.995	0.005
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.995	0.005
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.995	0.005
E79.1 Lesch-Nyhan syndrome	0.000	0.995	0.005
H33.0 Retinal detachment with retinal break	0.000	0.995	0.005
E32 Diseases of thymus	0.000	0.995	0.005
E28.3 Primary ovarian failure	0.000	0.995	0.005
E80.2 Other porphyria	0.000	0.995	0.005
E77.8 Other disorders of glycoprotein metabolism	0.000	0.995	0.005
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.995	0.005
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.995	0.005
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.995	0.005
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.995	0.005
E74.2 Disorders of galactose metabolism	0.000	0.995	0.005
E74.1 Disorders of fructose metabolism	0.000	0.995	0.005
E75.6 Lipid storage disorder, unspecified	0.000	0.995	0.005
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.995	0.005
E75.3 Sphingolipidosis, unspecified	0.000	0.995	0.005
E75.1 Other gangliosidosis	0.000	0.995	0.005
E75.0 GM2 gangliosidosis	0.000	0.995	0.005
E88.3 Tumour lysis syndrome	0.000	0.995	0.005
E75.2 Other sphingolipidosis	0.000	0.995	0.005
O01 Hydatidiform mole	0.005	0.995	0.000
E85.8 Other amyloidosis	0.000	0.995	0.005
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.995	0.005
O06 Unspecified abortion	0.005	0.995	0.000
O02.9 Abnormal product of conception, unspecified	0.005	0.995	0.000
E24 Cushing's syndrome	0.000	0.995	0.005
E23.0 Hypopituitarism	0.000	0.995	0.005
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.995	0.005
S92.20 Fracture of other tarsal bone(s) (closed)	0.000	0.995	0.005
E70.3 Albinism	0.000	0.995	0.005
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.995	0.005
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.995	0.005
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.995	0.005
S92.4 Fracture of great toe	0.000	0.995	0.005
E74.0 Glycogen storage disease	0.000	0.995	0.005
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.995	0.005
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.995	0.005
E23.7 Disorder of pituitary gland, unspecified	0.000	0.995	0.005
E73.8 Other lactose intolerance	0.000	0.995	0.005
E73.1 Secondary lactase deficiency	0.000	0.995	0.005
E73.0 Congenital lactase deficiency	0.000	0.995	0.005
O02.0 Blighted ovum and nonhydatidiform mole	0.005	0.995	0.000
E85.9 Amyloidosis, unspecified	0.000	0.995	0.005
O05 Other abortion	0.005	0.995	0.000
E88.8 Other specified metabolic disorders	0.000	0.995	0.005
I10 Essential (primary) hypertension	0.000	0.995	0.005
E22.0 Acromegaly and pituitary gigantism	0.000	0.995	0.005
E88.9 Metabolic disorder, unspecified	0.000	0.995	0.005
S92.31 Fracture of metatarsal bone (open)	0.000	0.995	0.005
E85.3 Secondary systemic amyloidosis	0.000	0.995	0.005
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.995	0.005
E75.5 Other lipid storage disorders	0.000	0.995	0.005
E23.6 Other disorders of pituitary gland	0.000	0.995	0.005
O07 Failed attempted abortion	0.005	0.995	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.995	0.005
S92.7 Multiple fractures of foot	0.000	0.995	0.005
S92.01 Fracture of calcaneus (open)	0.000	0.995	0.005
O04.1 Incomplete, complicated by delayed or excessive haemorrhage	0.005	0.995	0.000
E23.1 Drug-induced hypopituitarism	0.000	0.995	0.005
E20.1 Pseudohypoparathyroidism	0.000	0.995	0.005
E22.8 Other hyperfunction of pituitary gland	0.000	0.995	0.004
S92.9 Fracture of foot, unspecified	0.000	0.995	0.004
E23.2 Diabetes insipidus	0.000	0.995	0.004
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.995	0.004
E29.9 Testicular dysfunction, unspecified	0.000	0.995	0.004
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.995	0.004
E20.9 Hypoparathyroidism, unspecified	0.000	0.995	0.004
S92.5 Fracture of other toe	0.000	0.995	0.004
O04.7 Complete or unspecified, complicated by embolism	0.004	0.995	0.000
O04.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.004	0.995	0.000
O04.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.004	0.995	0.000
O04.3 Incomplete, with other and unspecified complications	0.004	0.995	0.000
O04.2 Incomplete, complicated by embolism	0.004	0.995	0.000
O04.0 Incomplete, complicated by genital tract and pelvic infection	0.004	0.995	0.000
E20.8 Other hypoparathyroidism	0.000	0.995	0.004
E85.4 Organ-limited amyloidosis	0.000	0.995	0.004
E20.0 Idiopathic hypoparathyroidism	0.000	0.995	0.004
E29.1 Testicular hypofunction	0.000	0.995	0.004
Z75.1 Person awaiting admission to adequate facility elsewhere	0.004	0.995	0.000
E26.9 Hyperaldosteronism, unspecified	0.000	0.996	0.004
E26.0 Primary hyperaldosteronism	0.000	0.996	0.004
E29.8 Other testicular dysfunction	0.000	0.996	0.004
E29.0 Testicular hyperfunction	0.000	0.996	0.004
S92.1 Fracture of talus	0.000	0.996	0.004
O04.8 Complete or unspecified, with other and unspecified complications	0.004	0.996	0.000
E22.1 Hyperprolactinaemia	0.000	0.996	0.004
O08.1 Delayed or excessive haemorrhage following abortion and ectopic and molar pregnancy	0.004	0.996	0.000
E26.8 Other hyperaldosteronism	0.000	0.996	0.004
E26.1 Secondary hyperaldosteronism	0.000	0.996	0.004
E73.9 Lactose intolerance, unspecified	0.000	0.996	0.004
E34.9 Endocrine disorder, unspecified	0.000	0.996	0.004
O08.0 Genital tract and pelvic infection following abortion and ectopic and molar pregnancy	0.004	0.996	0.000
S92.40 Fracture of great toe (closed)	0.000	0.996	0.004
E25.9 Adrenogenital disorder, unspecified	0.000	0.996	0.004
E25.8 Other adrenogenital disorders	0.000	0.996	0.004
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.996	0.004
E30.9 Disorder of puberty, unspecified	0.000	0.996	0.004
E30.8 Other disorders of puberty	0.000	0.996	0.004
E30.1 Precocious puberty	0.000	0.996	0.004
E30.0 Delayed puberty	0.000	0.996	0.004
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.996	0.004
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.996	0.004
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.996	0.004
S92.21 Fracture of other tarsal bone(s) (open)	0.000	0.996	0.004
E31.9 Polyglandular dysfunction, unspecified	0.000	0.996	0.004
E31.8 Other polyglandular dysfunction	0.000	0.996	0.004
E31.1 Polyglandular hyperfunction	0.000	0.996	0.004
E31.0 Autoimmune polyglandular failure	0.000	0.996	0.004
E34.5 Androgen resistance syndrome	0.000	0.996	0.004
E34.4 Constitutional tall stature	0.000	0.996	0.004
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.996	0.004
E34.1 Other hypersecretion of intestinal hormones	0.000	0.996	0.004
E66.8 Other obesity	0.000	0.996	0.004
O04.4 Incomplete, without complication	0.004	0.996	0.000
E34.3 Short stature, not elsewhere classified	0.000	0.996	0.004
O08.9 Complication following abortion and ectopic and molar pregnancy, unspecified	0.004	0.996	0.000
O08.8 Other complications following abortion and ectopic and molar pregnancy	0.004	0.996	0.000
O08.7 Other venous complications following abortion and ectopic and molar pregnancy	0.004	0.996	0.000
O08.6 Damage to pelvic organs and tissues following abortion and ectopic and molar pregnancy	0.004	0.996	0.000
O08.5 Metabolic disorders following abortion and ectopic and molar pregnancy	0.004	0.996	0.000
O08.4 Renal failure following abortion and ectopic and molar pregnancy	0.004	0.996	0.000
O08.3 Shock following abortion and ectopic and molar pregnancy	0.004	0.996	0.000
O08.2 Embolism following abortion and ectopic and molar pregnancy	0.004	0.996	0.000
O01.9 Hydatidiform mole, unspecified	0.004	0.996	0.000
O01.0 Classical hydatidiform mole	0.004	0.996	0.000
E24.2 Drug-induced Cushing's syndrome	0.000	0.996	0.004
E32.1 Abscess of thymus	0.000	0.996	0.004
E32.0 Persistent hyperplasia of thymus	0.000	0.996	0.004
E34.0 Carcinoid syndrome	0.000	0.996	0.004
E65-E68 Obesity and other hyperalimentation	0.000	0.996	0.004
E24.8 Other Cushing's syndrome	0.000	0.996	0.004
O06.4 Incomplete, without complication	0.004	0.996	0.000
O01.1 Incomplete and partial hydatidiform mole	0.004	0.996	0.000
E27 Other disorders of adrenal gland	0.000	0.996	0.004
E32.9 Disease of thymus, unspecified	0.000	0.996	0.004
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.996	0.004
E32.8 Other diseases of thymus	0.000	0.996	0.004
O06.9 Complete or unspecified, without complication	0.004	0.996	0.000
E40-E46 Malnutrition	0.000	0.996	0.004
O06.8 Complete or unspecified, with other and unspecified complications	0.004	0.996	0.000
O06.7 Complete or unspecified, complicated by embolism	0.004	0.996	0.000
O06.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.004	0.996	0.000
O06.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.004	0.996	0.000
O06.3 Incomplete, with other and unspecified complications	0.004	0.996	0.000
O06.2 Incomplete, complicated by embolism	0.004	0.996	0.000
O06.1 Incomplete, complicated by delayed or excessive haemorrhage	0.004	0.996	0.000
O06.0 Incomplete, complicated by genital tract and pelvic infection	0.004	0.996	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.996	0.004
E24.3 Ectopic ACTH syndrome	0.000	0.996	0.004
E24.1 Nelson's syndrome	0.000	0.996	0.004
E34.8 Other specified endocrine disorders	0.000	0.996	0.004
S92.41 Fracture of great toe (open)	0.000	0.996	0.004
M13.94 Arthritis, unspecified (Hand)	0.004	0.996	0.000
O05.9 Complete or unspecified, without complication	0.004	0.996	0.000
O05.8 Complete or unspecified, with other and unspecified complications	0.004	0.996	0.000
O05.7 Complete or unspecified, complicated by embolism	0.004	0.996	0.000
O05.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.004	0.996	0.000
O05.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.004	0.996	0.000
O05.4 Incomplete, without complication	0.004	0.996	0.000
O05.3 Incomplete, with other and unspecified complications	0.004	0.996	0.000
O05.2 Incomplete, complicated by embolism	0.004	0.996	0.000
O05.1 Incomplete, complicated by delayed or excessive haemorrhage	0.004	0.996	0.000
O05.0 Incomplete, complicated by genital tract and pelvic infection	0.004	0.996	0.000
E89.5 Postprocedural testicular hypofunction	0.000	0.996	0.004
S92.70 Multiple fractures of foot (closed)	0.000	0.996	0.004
S92.71 Multiple fractures of foot (open)	0.000	0.996	0.004
O07.9 Other and unspecified failed attempted abortion, without complication	0.004	0.996	0.000
O07.8 Other and unspecified failed attempted abortion, with other and unspecified complications	0.004	0.996	0.000
O07.7 Other and unspecified failed attempted abortion, complicated by embolism	0.004	0.996	0.000
O07.6 Other and unspecified failed attempted abortion, complicated by delayed or excessive haemorrhage	0.004	0.996	0.000
O07.5 Other and unspecified failed attempted abortion, complicated by genital tract and pelvic infection	0.004	0.996	0.000
O07.3 Failed medical abortion, with other and unspecified complications	0.004	0.996	0.000
O07.2 Failed medical abortion, complicated by embolism	0.004	0.996	0.000
O07.1 Failed medical abortion, complicated by delayed or excessive haemorrhage	0.004	0.996	0.000
O07.0 Failed medical abortion, complicated by genital tract and pelvic infection	0.004	0.996	0.000
E24.0 Pituitary-dependent Cushing's disease	0.000	0.996	0.003
M35.0 Sicca syndrome [Sjogren]	0.000	0.996	0.004
E89.2 Postprocedural hypoparathyroidism	0.000	0.996	0.004
S92.91 Fracture of foot, unspecified (open)	0.000	0.996	0.003
O07.4 Failed medical abortion, without complication	0.003	0.996	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.996	0.003
M13.90 Arthritis, unspecified (Multiple sites)	0.004	0.996	0.000
C45.0 Mesothelioma of pleura	0.004	0.996	0.000
S92.50 Fracture of other toe (closed)	0.000	0.996	0.003
E24.9 Cushing's syndrome, unspecified	0.000	0.997	0.003
S92.90 Fracture of foot, unspecified (closed)	0.000	0.997	0.003
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.997	0.003
S92.51 Fracture of other toe (open)	0.000	0.997	0.003
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.997	0.003
E27.2 Addisonian crisis	0.000	0.997	0.003
E89.1 Postprocedural hypoinsulinaemia	0.000	0.997	0.003
E89.4 Postprocedural ovarian failure	0.000	0.997	0.003
S92.11 Fracture of talus (open)	0.000	0.997	0.003
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.997	0.003
E66 Obesity	0.000	0.997	0.003
O34.2 Maternal care due to uterine scar from previous surgery	0.003	0.997	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.000	0.997	0.003
E65 Localised adiposity	0.000	0.997	0.003
S92.10 Fracture of talus (closed)	0.000	0.997	0.003
M84.03 Malunion of fracture (Forearm)	0.003	0.997	0.000
E16 Other disorders of pancreatic internal secretion	0.000	0.997	0.003
E67 Other hyperalimentation	0.000	0.997	0.003
E68 Sequelae of hyperalimentation	0.000	0.997	0.003
E46 Unspecified protein-energy malnutrition	0.000	0.997	0.003
E27.5 Adrenomedullary hyperfunction	0.000	0.997	0.003
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.997	0.003
E27.0 Other adrenocortical overactivity	0.000	0.997	0.003
O03 Spontaneous abortion	0.003	0.997	0.000
E15 Nondiabetic hypoglycaemic coma	0.000	0.997	0.003
M13.9 Arthritis, unspecified	0.003	0.997	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.997	0.003
E45 Retarded development following protein-energy malnutrition	0.000	0.997	0.003
E43 Unspecified severe protein-energy malnutrition	0.000	0.997	0.003
E42 Marasmic kwashiorkor	0.000	0.997	0.003
E41 Nutritional marasmus	0.000	0.997	0.003
E40 Kwashiorkor	0.000	0.997	0.003
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.997	0.003
E89.3 Postprocedural hypopituitarism	0.000	0.997	0.003
I64 Stroke, not specified as haemorrhage or infarction	0.000	0.997	0.003
N88.2 Stricture and stenosis of cervix uteri	0.003	0.997	0.000
S90-S99 Injuries to the ankle and foot	0.000	0.997	0.003
M13.96 Arthritis, unspecified (Lower leg)	0.003	0.997	0.000
M13.97 Arthritis, unspecified (Ankle and foot)	0.003	0.997	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.997	0.003
E27.1 Primary adrenocortical insufficiency	0.000	0.997	0.003
M67.8 Other specified disorders of synovium and tendon	0.003	0.997	0.000
E27.9 Disorder of adrenal gland, unspecified	0.000	0.997	0.002
E50-E64 Other nutritional deficiencies	0.000	0.997	0.003
O34 Maternal care for known or suspected abnormality of pelvic organs	0.003	0.997	0.000
T81.3 Disruption of operation wound, not elsewhere classified	0.003	0.997	0.000
C45 Mesothelioma	0.003	0.997	0.000
O03.8 Complete or unspecified, with other and unspecified complications	0.003	0.997	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.000	0.997	0.003
E66.1 Drug-induced obesity	0.000	0.997	0.003
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.997	0.002
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.002	0.997	0.000
E27.8 Other specified disorders of adrenal gland	0.000	0.997	0.002
M81.9 Osteoporosis, unspecified	0.000	0.997	0.003
O03.3 Incomplete, with other and unspecified complications	0.002	0.997	0.000
E67.8 Other specified hyperalimentation	0.000	0.997	0.002
E67.3 Hypervitaminosis D	0.000	0.997	0.002
E67.2 Megavitamin-B6 syndrome	0.000	0.997	0.002
E67.1 Hypercarotenaemia	0.000	0.997	0.002
E67.0 Hypervitaminosis A	0.000	0.997	0.002
C45.7 Mesothelioma of other sites	0.003	0.997	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.997	0.002
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.997	0.002
E16.4 Abnormal secretion of gastrin	0.000	0.997	0.002
E16.3 Increased secretion of glucagon	0.000	0.997	0.002
E16.2 Hypoglycaemia, unspecified	0.000	0.997	0.003
E66.0 Obesity due to excess calories	0.000	0.997	0.002
O03.7 Complete or unspecified, complicated by embolism	0.002	0.997	0.000
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.002	0.997	0.000
O03.2 Incomplete, complicated by embolism	0.002	0.997	0.000
O03.1 Incomplete, complicated by delayed or excessive haemorrhage	0.002	0.997	0.000
O03.0 Incomplete, complicated by genital tract and pelvic infection	0.002	0.997	0.000
M13.98 Arthritis, unspecified (Other)	0.002	0.997	0.000
E16.1 Other hypoglycaemia	0.000	0.997	0.002
E44.1 Mild protein-energy malnutrition	0.000	0.997	0.002
E44.0 Moderate protein-energy malnutrition	0.000	0.997	0.002
O34.8 Maternal care for other abnormalities of pelvic organs	0.002	0.997	0.000
M13.92 Arthritis, unspecified (Upper arm)	0.002	0.997	0.000
C45.9 Mesothelioma, unspecified	0.002	0.997	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.997	0.002
O34.1 Maternal care for tumour of corpus uteri	0.002	0.997	0.000
S97 Crushing injury of ankle and foot	0.000	0.997	0.002
S91 Open wound of ankle and foot	0.000	0.998	0.002
I71 Aortic aneurysm and dissection	0.000	0.998	0.002
S95 Injury of blood vessels at ankle and foot level	0.000	0.998	0.002
S94 Injury of nerves at ankle and foot level	0.000	0.998	0.002
O34.0 Maternal care for congenital malformation of uterus	0.002	0.998	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.000	0.998	0.002
O34.4 Maternal care for other abnormalities of cervix	0.002	0.998	0.000
M47.96 Spondylosis, unspecified (Lumbar region)	0.002	0.998	0.000
S93.1 Dislocation of toe(s)	0.000	0.998	0.002
S98 Traumatic amputation of ankle and foot	0.000	0.998	0.002
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.000	0.998	0.002
I60.9 Subarachnoid haemorrhage, unspecified	0.002	0.998	0.000
E58 Dietary calcium deficiency	0.000	0.998	0.002
S99 Other and unspecified injuries of ankle and foot	0.000	0.998	0.002
S96 Injury of muscle and tendon at ankle and foot level	0.000	0.998	0.002
M81.91 Osteoporosis, unspecified (Shoulder region)	0.000	0.998	0.002
O34.6 Maternal care for abnormality of vagina	0.002	0.998	0.000
S93.0 Dislocation of ankle joint	0.000	0.998	0.002
M87.9 Osteonecrosis, unspecified	0.002	0.998	0.000
E61 Deficiency of other nutrient elements	0.000	0.998	0.002
M81.93 Osteoporosis, unspecified (Forearm)	0.000	0.998	0.002
O20.0 Threatened abortion	0.000	0.998	0.002
O34.3 Maternal care for cervical incompetence	0.002	0.998	0.000
S90 Superficial injury of ankle and foot	0.000	0.998	0.002
M13.93 Arthritis, unspecified (Forearm)	0.002	0.998	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.000	0.998	0.002
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.998	0.002
E63 Other nutritional deficiencies	0.000	0.998	0.002
E50 Vitamin A deficiency	0.000	0.998	0.002
E60 Dietary zinc deficiency	0.000	0.998	0.002
E59 Dietary selenium deficiency	0.000	0.998	0.002
E52 Niacin deficiency [pellagra]	0.000	0.998	0.002
C45.2 Mesothelioma of pericardium	0.002	0.998	0.000
O34.5 Maternal care for other abnormalities of gravid uterus	0.002	0.998	0.000
E54 Ascorbic acid deficiency	0.000	0.998	0.002
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.002	0.998	0.000
N88.9 Noninflammatory disorder of cervix uteri, unspecified	0.002	0.998	0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.002	0.998	0.000
M47.92 Spondylosis, unspecified (Cervical region)	0.002	0.998	0.000
C45.1 Mesothelioma of peritoneum	0.002	0.998	0.000
N88 Other noninflammatory disorders of cervix uteri	0.002	0.998	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.000	0.998	0.002
S93.4 Sprain and strain of ankle	0.000	0.998	0.002
S93.5 Sprain and strain of toe(s)	0.000	0.998	0.002
E51 Thiamine deficiency	0.000	0.998	0.002
M89.0 Algoneurodystrophy	0.002	0.998	0.000
M84.0 Malunion of fracture	0.002	0.998	0.000
S91.0 Open wound of ankle	0.000	0.998	0.002
S93.3 Dislocation of other and unspecified parts of foot	0.000	0.998	0.002
S93.2 Rupture of ligaments at ankle and foot level	0.000	0.998	0.002
E56 Other vitamin deficiencies	0.000	0.998	0.002
E89.0 Postprocedural hypothyroidism	0.000	0.998	0.002
M89 Other disorders of bone	0.002	0.998	0.000
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.002	0.998	0.000
S97.1 Crushing injury of toe(s)	0.000	0.998	0.002
M81.98 Osteoporosis, unspecified (Other)	0.000	0.998	0.002
M81.92 Osteoporosis, unspecified (Upper arm)	0.000	0.998	0.002
O62.0 Primary inadequate contractions	0.002	0.998	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
M67.2 Synovial hypertrophy, not elsewhere classified	0.002	0.998	0.000
S91.2 Open wound of toe(s) with damage to nail	0.000	0.998	0.002
M67 Other disorders of synovium and tendon	0.002	0.998	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.002	0.998	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.000	0.998	0.002
O62.2 Other uterine inertia	0.002	0.998	0.000
S91.7 Multiple open wounds of ankle and foot	0.000	0.998	0.002
S97.8 Crushing injury of other parts of ankle and foot	0.000	0.998	0.002
S97.0 Crushing injury of ankle	0.000	0.998	0.002
M35 Other systemic involvement of connective tissue	0.000	0.998	0.002
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.998	0.002
S91.3 Open wound of other parts of foot	0.000	0.998	0.002
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.998	0.002
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.998	0.002
M13.91 Arthritis, unspecified (Shoulder region)	0.002	0.998	0.000
M47.9 Spondylosis, unspecified	0.002	0.998	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.000	0.998	0.002
S94.8 Injury of other nerves at ankle and foot level	0.000	0.998	0.002
S94.7 Injury of multiple nerves at ankle and foot level	0.000	0.998	0.002
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.000	0.998	0.002
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.000	0.998	0.002
S94.1 Injury of medial plantar nerve	0.000	0.998	0.002
S94.0 Injury of lateral plantar nerve	0.000	0.998	0.002
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.000	0.998	0.002
S95.8 Injury of other blood vessels at ankle and foot level	0.000	0.998	0.002
S95.7 Injury of multiple blood vessels at ankle and foot level	0.000	0.998	0.002
S95.2 Injury of dorsal vein of foot	0.000	0.998	0.002
S95.1 Injury of plantar artery of foot	0.000	0.998	0.002
S95.0 Injury of dorsal artery of foot	0.000	0.998	0.002
S99.8 Other specified injuries of ankle and foot	0.000	0.998	0.002
M87 Osteonecrosis	0.002	0.998	0.000
Y86 Sequelae of other accidents	0.002	0.998	0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.002	0.998	0.000
S82.10 Fracture of upper end of tibia (closed)	0.000	0.998	0.002
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.998	0.002
J35.8 Other chronic diseases of tonsils and adenoids	0.000	0.998	0.002
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.000	0.998	0.002
M84.04 Malunion of fracture (Hand)	0.002	0.998	0.000
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.002	0.998	0.000
N88.1 Old laceration of cervix uteri	0.002	0.998	0.000
S42.20 Fracture of upper end of humerus (closed)	0.002	0.998	0.000
M89.5 Osteolysis	0.002	0.998	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.000	0.998	0.002
S98.4 Traumatic amputation of foot, level unspecified	0.000	0.998	0.002
S98.3 Traumatic amputation of other parts of foot	0.000	0.998	0.002
S98.2 Traumatic amputation of two or more toes	0.000	0.998	0.002
S98.0 Traumatic amputation of foot at ankle level	0.000	0.998	0.002
O62 Abnormalities of forces of labour	0.002	0.998	0.000
M87.98 Osteonecrosis, unspecified (Other)	0.002	0.998	0.000
M87.96 Osteonecrosis, unspecified (Lower leg)	0.002	0.998	0.000
M89.07 Algoneurodystrophy (Ankle and foot)	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations