TreeWAS – Variant ID: rs73727981

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.000	1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.000	1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.000	1.000
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
E05.0 Thyrotoxicosis with diffuse goitre	1.000	0.000	0.000
K90.0 Coeliac disease	1.000	0.000	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.000	1.000
M06.9 Rheumatoid arthritis, unspecified	0.000	0.000	1.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
M06 Other rheumatoid arthritis	0.000	0.000	1.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
E03 Other hypothyroidism	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
N00-N08 Glomerular diseases	1.000	0.000	0.000
D80-D89 Certain disorders involving the immune mechanism	1.000	0.000	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	1.000	0.000	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.000	1.000
D86 Sarcoidosis	1.000	0.000	0.000
E20-E35 Disorders of other endocrine glands	1.000	0.000	0.000
N17-N19 Renal failure	1.000	0.000	0.000
N18 Chronic renal failure	0.999	0.001	0.000
E10.9 Without complications	0.999	0.001	0.000
Chapter XIV Diseases of the genitourinary system	0.999	0.001	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.001	0.999
# Top node	0.999	0.001	0.000
M06.3 Rheumatoid nodule	0.000	0.001	0.999
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.999	0.001	0.000
N04 Nephrotic syndrome	0.998	0.002	0.000
M05 Seropositive rheumatoid arthritis	0.000	0.002	0.997
Q60-Q64 Congenital malformations of the urinary system	0.997	0.003	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.996	0.004	0.000
N05 Unspecified nephritic syndrome	0.996	0.004	0.000
M05-M14 Inflammatory polyarthropathies	0.000	0.004	0.996
N18.3 Chronic kidney disease, stage 3	0.996	0.004	0.000
M06.0 Seronegative rheumatoid arthritis	0.000	0.005	0.995
E27 Other disorders of adrenal gland	0.992	0.008	0.000
D86.9 Sarcoidosis, unspecified	0.991	0.009	0.000
Q61 Cystic kidney disease	0.991	0.009	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.010	0.990
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.010	0.990
M06.34 Rheumatoid nodule (Hand)	0.000	0.011	0.989
D69 Purpura and other haemorrhagic conditions	0.988	0.012	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.013	0.987
N04.9 Unspecified	0.987	0.013	0.000
E10.1 With ketoacidosis	0.986	0.014	0.000
E10.3 With ophthalmic complications	0.986	0.014	0.000
K90 Intestinal malabsorption	0.986	0.014	0.000
D86.0 Sarcoidosis of lung	0.986	0.014	0.000
E27.1 Primary adrenocortical insufficiency	0.985	0.015	0.000
E83.1 Disorders of iron metabolism	0.000	0.017	0.983
K90.9 Intestinal malabsorption, unspecified	0.979	0.021	0.000
Chapter VII Diseases of the eye and adnexa	0.978	0.022	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.023	0.977
Q38-Q45 Other congenital malformations of the digestive system	0.977	0.023	0.000
Q61.3 Polycystic kidney, unspecified	0.977	0.023	0.000
E28 Ovarian dysfunction	0.977	0.023	0.000
N17 Acute renal failure	0.976	0.024	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.024	0.976
N08 Glomerular disorders in diseases classified elsewhere	0.974	0.026	0.000
N05.2 Diffuse membranous glomerulonephritis	0.969	0.031	0.000
H30-H36 Disorders of choroid and retina	0.967	0.033	0.000
E14 Unspecified diabetes mellitus	0.960	0.040	0.000
N17.9 Acute renal failure, unspecified	0.960	0.040	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.959	0.041	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.958	0.042	0.000
H06.2 Dysthyroid exophthalmos	0.957	0.043	0.000
N05.9 Unspecified	0.954	0.046	0.000
D69.6 Thrombocytopenia, unspecified	0.952	0.048	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.951	0.049	0.000
N18.9 Chronic renal failure, unspecified	0.950	0.050	0.000
E28.2 Polycystic ovarian syndrome	0.949	0.051	0.000
N08.3 Glomerular disorders in diabetes mellitus	0.945	0.055	0.000
D68 Other coagulation defects	0.942	0.058	0.000
D69.4 Other primary thrombocytopenia	0.939	0.061	0.000
H35 Other retinal disorders	0.934	0.066	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.932	0.068	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.000	0.072	0.928
H00.1 Chalazion	0.000	0.074	0.926
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.076	0.924
N04.2 Diffuse membranous glomerulonephritis	0.921	0.079	0.000
N18.2 Chronic kidney disease, stage 2	0.918	0.082	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.917	0.083	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.084	0.916
M06.32 Rheumatoid nodule (Upper arm)	0.000	0.084	0.916
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.915	0.085	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.000	0.086	0.914
Q61.2 Polycystic kidney, adult type	0.914	0.086	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.912	0.088	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.912	0.088	0.000
H35.4 Peripheral retinal degeneration	0.910	0.090	0.000
H50 Other strabismus	0.905	0.095	0.000
E10.2 With renal complications	0.897	0.103	0.000
E03.8 Other specified hypothyroidism	0.896	0.104	0.000
D86.3 Sarcoidosis of skin	0.896	0.104	0.000
N25-N29 Other disorders of kidney and ureter	0.895	0.105	0.000
D68.8 Other specified coagulation defects	0.895	0.105	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.000	0.114	0.886
E24 Cushing's syndrome	0.884	0.116	0.000
H34 Retinal vascular occlusions	0.881	0.119	0.000
N18.5 Chronic kidney disease, stage 5	0.876	0.124	0.000
Q60.0 Renal agenesis, unilateral	0.875	0.125	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.126	0.874
H33 Retinal detachments and breaks	0.868	0.132	0.000
H35.8 Other specified retinal disorders	0.867	0.133	0.000
E27.9 Disorder of adrenal gland, unspecified	0.866	0.134	0.000
H50.5 Heterophoria	0.865	0.135	0.000
D68.5 Primary Thrombophilia	0.864	0.136	0.000
Q43 Other congenital malformations of intestine	0.863	0.137	0.000
D80 Immunodeficiency with predominantly antibody defects	0.861	0.139	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.858	0.142	0.000
N28 Other disorders of kidney and ureter, not elsewhere classified	0.857	0.143	0.000
E10.0 With coma	0.852	0.148	0.000
E21.3 Hyperparathyroidism, unspecified	0.851	0.149	0.000
N28.9 Disorder of kidney and ureter, unspecified	0.851	0.149	0.000
E16 Other disorders of pancreatic internal secretion	0.849	0.151	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.849	0.151	0.000
H34.8 Other retinal vascular occlusions	0.846	0.154	0.000
Q00-Q07 Congenital malformations of the nervous system	0.845	0.155	0.000
Q44.6 Cystic disease of liver	0.845	0.155	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.160	0.840
H35.2 Other proliferative retinopathy	0.840	0.160	0.000
N04.1 Focal and segmental glomerular lesions	0.839	0.161	0.000
Q60.2 Renal agenesis, unspecified	0.835	0.165	0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.835	0.165	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.833	0.167	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.167	0.833
H43-H45 Disorders of vitreous body and globe	0.831	0.169	0.000
E06 Thyroiditis	0.829	0.171	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.827	0.173	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.826	0.174	0.000
H05 Disorders of orbit	0.825	0.175	0.000
E14.8 With unspecified complications	0.821	0.179	0.000
C82.0 Small cleaved cell, follicular	0.000	0.180	0.820
H50.2 Vertical strabismus	0.820	0.180	0.000
E28.3 Primary ovarian failure	0.814	0.186	0.000
H33.4 Traction detachment of retina	0.812	0.188	0.000
E14.3 With ophthalmic complications	0.811	0.189	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.809	0.191	0.000
D86.8 Sarcoidosis of other and combined sites	0.804	0.196	0.000
N05.1 Focal and segmental glomerular lesions	0.801	0.199	0.000
N08.5 Glomerular disorders in systemic connective tissue disorders	0.796	0.204	0.000
H43 Disorders of vitreous body	0.795	0.205	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.000	0.206	0.794
E24.2 Drug-induced Cushing's syndrome	0.794	0.206	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.208	0.792
E07 Other disorders of thyroid	0.792	0.208	0.000
E14.9 Without complications	0.790	0.210	0.000
Q63 Other congenital malformations of kidney	0.788	0.212	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.214	0.786
Q61.9 Cystic kidney disease, unspecified	0.783	0.217	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.000	0.220	0.780
H33.1 Retinoschisis and retinal cysts	0.778	0.222	0.000
H05.2 Exophthalmic conditions	0.778	0.222	0.000
H35.0 Background retinopathy and retinal vascular changes	0.776	0.224	0.000
E14.1 With ketoacidosis	0.776	0.224	0.000
C82.2 Large cell, follicular	0.000	0.226	0.774
D89.2 Hypergammaglobulinaemia, unspecified	0.771	0.229	0.000
D68.6 Other Thrombophilia	0.769	0.231	0.000
E16.2 Hypoglycaemia, unspecified	0.769	0.231	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.767	0.233	0.000
H43.8 Other disorders of vitreous body	0.765	0.235	0.000
C82.3 Follicular lymphoma grade IIIa	0.000	0.238	0.762
D69.9 Haemorrhagic condition, unspecified	0.761	0.238	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.000	0.239	0.761
N17.0 Acute renal failure with tubular necrosis	0.759	0.241	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.759	0.241	0.000
H00 Hordeolum and chalazion	0.187	0.241	0.572
K90.8 Other intestinal malabsorption	0.759	0.241	0.000
D68.1 Hereditary factor XI deficiency	0.759	0.241	0.000
H50.6 Mechanical strabismus	0.758	0.242	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.758	0.242	0.000
E29 Testicular dysfunction	0.757	0.243	0.000
E10.4 With neurological complications	0.754	0.246	0.000
E31 Polyglandular dysfunction	0.753	0.247	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.749	0.251	0.000
D83 Common variable immunodeficiency	0.748	0.252	0.000
L40.9 Psoriasis, unspecified	0.000	0.255	0.745
H50.9 Strabismus, unspecified	0.745	0.255	0.000
E14.4 With neurological complications	0.744	0.256	0.000
E10.7 With multiple complications	0.741	0.259	0.000
D68.0 Von Willebrand's disease	0.740	0.260	0.000
D60-D64 Aplastic and other anaemias	0.740	0.260	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.739	0.261	0.000
Q40 Other congenital malformations of upper alimentary tract	0.737	0.263	0.000
D69.8 Other specified haemorrhagic conditions	0.735	0.265	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.734	0.266	0.000
M14 Arthropathies in other diseases classified elsewhere	0.000	0.266	0.734
H33.0 Retinal detachment with retinal break	0.731	0.269	0.000
E14.5 With peripheral circulatory complications	0.731	0.269	0.000
Q44.4 Choledochal cyst	0.730	0.270	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.728	0.272	0.000
N00 Acute nephritic syndrome	0.725	0.275	0.000
D86.1 Sarcoidosis of lymph nodes	0.725	0.275	0.000
H03 Disorders of eyelid in diseases classified elsewhere	0.723	0.277	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.718	0.282	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.718	0.282	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.282	0.718
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.283	0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.283	0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.283	0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.283	0.717
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.717	0.283	0.000
M06.8 Other specified rheumatoid arthritis	0.000	0.283	0.717
M06.2 Rheumatoid bursitis	0.000	0.283	0.717
M06.1 Adult-onset Still's disease	0.000	0.283	0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E03.5 Myxoedema coma	0.717	0.283	0.000
E03.4 Atrophy of thyroid (acquired)	0.717	0.283	0.000
E03.3 Postinfectious hypothyroidism	0.717	0.283	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
N07 Hereditary nephropathy, not elsewhere classified	0.717	0.283	0.000
N06 Isolated proteinuria with specified morphological lesion	0.717	0.283	0.000
N01 Rapidly progressive nephritic syndrome	0.717	0.283	0.000
D81 Combined immunodeficiencies	0.717	0.283	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.717	0.283	0.000
E32 Diseases of thymus	0.717	0.283	0.000
E30 Disorders of puberty, not elsewhere classified	0.717	0.283	0.000
E25 Adrenogenital disorders	0.717	0.283	0.000
E20 Hypoparathyroidism	0.717	0.283	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.000	0.284	0.716
M06.38 Rheumatoid nodule (Other)	0.000	0.284	0.716
M06.36 Rheumatoid nodule (Lower leg)	0.000	0.284	0.716
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.000	0.284	0.716
M06.33 Rheumatoid nodule (Forearm)	0.000	0.284	0.716
M06.31 Rheumatoid nodule (Shoulder region)	0.000	0.284	0.716
N04.8 Other	0.715	0.285	0.000
N04.7 Diffuse crescentic glomerulonephritis	0.715	0.285	0.000
N04.6 Dense deposit disease	0.715	0.285	0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis	0.715	0.285	0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis	0.715	0.285	0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis	0.715	0.285	0.000
M05.8 Other seropositive rheumatoid arthritis	0.000	0.285	0.715
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.000	0.285	0.715
M05.1 Rheumatoid lung disease	0.000	0.285	0.715
M05.0 Felty's syndrome	0.000	0.285	0.715
N18.0 End-stage renal disease	0.715	0.285	0.000
N05.6 Dense deposit disease	0.714	0.286	0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis	0.714	0.286	0.000
N05.0 Minor glomerular abnormality	0.714	0.286	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.000	0.286	0.714
M08 Juvenile arthritis	0.000	0.286	0.714
M06.08 Seronegative rheumatoid arthritis (Other)	0.000	0.286	0.713
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.000	0.286	0.713
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.000	0.286	0.713
M06.04 Seronegative rheumatoid arthritis (Hand)	0.000	0.286	0.713
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.000	0.286	0.713
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.000	0.286	0.713
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.000	0.286	0.713
E14.2 Withrenal complications	0.713	0.287	0.000
D55-D59 Haemolytic anaemias	0.712	0.288	0.000
E26 Hyperaldosteronism	0.712	0.288	0.000
E83 Disorders of mineral metabolism	0.001	0.288	0.711
N02 Recurrent and persistent haematuria	0.711	0.289	0.000
E27.5 Adrenomedullary hyperfunction	0.711	0.289	0.000
E27.0 Other adrenocortical overactivity	0.711	0.289	0.000
E24.0 Pituitary-dependent Cushing's disease	0.711	0.289	0.000
Q61.8 Other cystic kidney diseases	0.710	0.290	0.000
Q61.1 Polycystic kidney, infantile type	0.710	0.290	0.000
M05.2 Rheumatoid vasculitis	0.000	0.291	0.709
N03 Chronic nephritic syndrome	0.709	0.291	0.000
H36 Retinal disorders in diseases classified elsewhere	0.707	0.293	0.000
K90.3 Pancreatic steatorrhoea	0.707	0.293	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.707	0.293	0.000
K90.1 Tropical sprue	0.707	0.293	0.000
E06.5 Other chronic thyroiditis	0.706	0.294	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.705	0.295	0.000
E83.3 Disorders of phosphorus metabolism	0.000	0.296	0.704
D82 Immunodeficiency associated with other major defects	0.704	0.296	0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis	0.702	0.298	0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases	0.701	0.299	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.700	0.300	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.700	0.300	0.000
E28.9 Ovarian dysfunction, unspecified	0.700	0.300	0.000
E28.8 Other ovarian dysfunction	0.700	0.300	0.000
E28.1 Androgen excess	0.700	0.300	0.000
E28.0 Oestrogen excess	0.700	0.300	0.000
N17.2 Acute renal failure with medullary necrosis	0.700	0.300	0.000
N08.8 Glomerular disorders in other diseases classified elsewhere	0.698	0.302	0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism	0.698	0.302	0.000
N08.1 Glomerular disorders in neoplastic diseases	0.698	0.302	0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere	0.698	0.302	0.000
M06.4 Inflammatory polyarthropathy	0.000	0.302	0.698
E40-E46 Malnutrition	0.697	0.303	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.693	0.307	0.000
E07.8 Other specified disorders of thyroid	0.692	0.308	0.000
Q35-Q37 Cleft lip and cleft palate	0.691	0.309	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.691	0.309	0.000
D69.1 Qualitative platelet defects	0.689	0.311	0.000
E14.7 With multiple complications	0.688	0.311	0.000
E14.0 With coma	0.688	0.311	0.000
N04.0 Minor glomerular abnormality	0.688	0.312	0.000
N18.1 Chronic kidney disease, stage 1	0.688	0.312	0.000
H06.3 Other disorders of orbit in diseases classified elsewhere	0.687	0.313	0.000
H06.1 Parasitic infestation of orbit in diseases classified elsewhere	0.687	0.313	0.000
H06.0 Disorders of lachrymal system in diseases classified elsewhere	0.687	0.313	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.685	0.315	0.000
D89.1 Cryoglobulinaemia	0.684	0.316	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.684	0.316	0.000
Q63.2 Ectopic kidney	0.683	0.317	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.682	0.318	0.000
Q60.6 Potter's syndrome	0.682	0.318	0.000
Q60.5 Renal hypoplasia, unspecified	0.682	0.318	0.000
Q60.4 Renal hypoplasia, bilateral	0.682	0.318	0.000
Q60.3 Renal hypoplasia, unilateral	0.682	0.318	0.000
Q60.1 Renal agenesis, bilateral	0.682	0.318	0.000
Q39 Congenital malformations of oesophagus	0.682	0.318	0.000
Q61.4 Renal dysplasia	0.681	0.318	0.000
Q38.7 Pharyngeal pouch	0.681	0.319	0.000
N17.1 Acute renal failure with acute cortical necrosis	0.678	0.322	0.000
C82.4 Follicular lymphoma grade IIIb	0.000	0.322	0.678
Q43.0 Meckel's diverticulum	0.678	0.322	0.000
Q05 Spina bifida	0.676	0.324	0.000
D69.2 Other nonthrombocytopenic purpura	0.675	0.325	0.000
N05.8 Other	0.674	0.325	0.000
N02.2 Diffuse membranous glomerulonephritis	0.674	0.326	0.000
H50.8 Other specified strabismus	0.673	0.326	0.000
N25 Disorders resulting from impaired renal tubular function	0.670	0.330	0.000
H35.1 Retinopathy of prematurity	0.670	0.330	0.000
D69.0 Allergic purpura	0.670	0.330	0.000
D89.3 Immune reconstitution syndrome	0.668	0.332	0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere	0.668	0.332	0.000
Q61.0 Congenital single renal cyst	0.666	0.334	0.000
E21.0 Primary hyperparathyroidism	0.665	0.335	0.000
Q44.5 Other congenital malformations of bile ducts	0.663	0.337	0.000
E34 Other endocrine disorders	0.661	0.339	0.000
N18.4 Chronic kidney disease, stage 4	0.661	0.339	0.000
E21.4 Other specified disorders of parathyroid gland	0.658	0.342	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.657	0.342	0.000
E15 Nondiabetic hypoglycaemic coma	0.654	0.346	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.654	0.346	0.000
Q44.2 Atresia of bile ducts	0.654	0.346	0.000
Q44.1 Other congenital malformations of gallbladder	0.654	0.346	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.654	0.346	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.653	0.347	0.000
Q44.7 Other congenital malformations of liver	0.652	0.347	0.000
N28.0 Ischaemia and infarction of kidney	0.650	0.350	0.000
H50.3 Intermittent heterotropia	0.649	0.351	0.000
M12 Other specific arthropathies	0.000	0.351	0.648
Q03 Congenital hydrocephalus	0.647	0.353	0.000
H43.2 Crystalline deposits in vitreous body	0.647	0.353	0.000
N17.8 Other acute renal failure	0.646	0.354	0.000
Q80-Q89 Other congenital malformations	0.645	0.355	0.000
D67 Hereditary factor IX deficiency	0.644	0.356	0.000
Q61.5 Medullary cystic kidney	0.643	0.357	0.000
Q38.6 Other congenital malformations of mouth	0.642	0.358	0.000
H30 Chorioretinal inflammation	0.641	0.358	0.000
D68.4 Acquired coagulation factor deficiency	0.641	0.359	0.000
H43.3 Other vitreous opacities	0.641	0.359	0.000
E10.8 With unspecified complications	0.639	0.360	0.000
Q64 Other congenital malformations of urinary system	0.639	0.360	0.000
Q43.3 Congenital malformations of intestinal fixation	0.639	0.361	0.000
Q45 Other congenital malformations of digestive system	0.639	0.361	0.000
E24.8 Other Cushing's syndrome	0.639	0.361	0.000
D61 Other aplastic anaemias	0.639	0.361	0.000
Q38.1 Ankyloglossia	0.638	0.362	0.000
C82.6 Cutaneous follicle centre lymphoma	0.000	0.365	0.635
C82.5 Diffuse follicle centre lymphoma	0.000	0.365	0.635
C82.1 Mixed small cleaved and large cell, follicular	0.000	0.365	0.635
E03.1 Congenital hypothyroidism without goitre	0.634	0.365	0.000
Q04 Other congenital malformations of brain	0.634	0.366	0.000
E23 Hypofunction and other disorders of pituitary gland	0.634	0.366	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.634	0.366	0.000
E24.3 Ectopic ACTH syndrome	0.634	0.366	0.000
E24.1 Nelson's syndrome	0.634	0.366	0.000
D84 Other immunodeficiencies	0.634	0.366	0.000
E21.2 Other hyperparathyroidism	0.633	0.367	0.000
Q07 Other congenital malformations of nervous system	0.633	0.367	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.632	0.368	0.000
H34.0 Transient retinal artery occlusion	0.632	0.368	0.000
D50-D53 Nutritional anaemias	0.631	0.369	0.000
H05.8 Other disorders of orbit	0.631	0.369	0.000
H50.0 Convergent concomitant strabismus	0.630	0.370	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.629	0.370	0.000
N18.8 Other chronic renal failure	0.628	0.371	0.000
E06.9 Thyroiditis, unspecified	0.622	0.378	0.000
Q43.7 Persistent cloaca	0.618	0.381	0.000
Q43.6 Congenital fistula of rectum and anus	0.618	0.381	0.000
Q43.5 Ectopic anus	0.618	0.381	0.000
Q43.4 Duplication of intestine	0.618	0.381	0.000
Q43.2 Other congenital functional disorders of colon	0.618	0.381	0.000
E10.5 With peripheral circulatory complications	0.618	0.382	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.617	0.382	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.617	0.382	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.617	0.382	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.617	0.382	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.617	0.382	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.617	0.382	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.616	0.383	0.000
H50.4 Other and unspecified heterotropia	0.616	0.384	0.000
M07 Psoriatic and enteropathic arthropathies	0.000	0.385	0.615
Q43.8 Other specified congenital malformations of intestine	0.614	0.385	0.000
Q68 Other congenital musculoskeletal deformities	0.614	0.386	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.612	0.388	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.609	0.391	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.609	0.391	0.000
E16.4 Abnormal secretion of gastrin	0.609	0.391	0.000
E16.3 Increased secretion of glucagon	0.609	0.391	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.609	0.391	0.000
H43.9 Disorder of vitreous body, unspecified	0.609	0.391	0.000
E06.1 Subacute thyroiditis	0.608	0.392	0.000
Q06 Other congenital malformations of spinal cord	0.606	0.394	0.000
Q01 Encephalocele	0.606	0.394	0.000
Q00 Anencephaly and similar malformations	0.606	0.394	0.000
Q02 Microcephaly	0.606	0.394	0.000
E16.1 Other hypoglycaemia	0.603	0.397	0.000
H34.9 Retinal vascular occlusion, unspecified	0.602	0.397	0.000
H35.6 Retinal haemorrhage	0.602	0.398	0.000
E05.8 Other thyrotoxicosis	0.601	0.398	0.000
Q38.8 Other congenital malformations of pharynx	0.598	0.402	0.000
Q38.5 Congenital malformations of palate, not elsewhere classified	0.598	0.402	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.598	0.402	0.000
Q38.3 Other congenital malformations of tongue	0.598	0.402	0.000
Q38.2 Macroglossia	0.598	0.402	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.598	0.402	0.000
Q70 Syndactyly	0.597	0.403	0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.596	0.404	0.000
E27.2 Addisonian crisis	0.595	0.404	0.000
E06.4 Drug-induced thyroiditis	0.594	0.406	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.594	0.406	0.000
E06.0 Acute thyroiditis	0.594	0.406	0.000
N27 Small kidney of unknown cause	0.593	0.407	0.000
H03.8 Involvement of eyelid in other diseases classified elsewhere	0.592	0.408	0.000
Q43.1 Hirschsprung's disease	0.592	0.408	0.000
H05.5 Retained (old) foreign body following penetrating wound of orbit	0.592	0.408	0.000
H05.3 Deformity of orbit	0.592	0.408	0.000
H05.1 Chronic inflammatory disorders of orbit	0.592	0.408	0.000
Q31 Congenital malformations of larynx	0.587	0.413	0.000
Q76 Congenital malformations of spine and bony thorax	0.586	0.414	0.000
H51 Other disorders of binocular movement	0.586	0.414	0.000
E29.1 Testicular hypofunction	0.583	0.417	0.000
M11 Other crystal arthropathies	0.000	0.418	0.581
N05.7 Diffuse crescentic glomerulonephritis	0.580	0.420	0.000
H35.5 Hereditary retinal dystrophy	0.579	0.421	0.000
E31.0 Autoimmune polyglandular failure	0.576	0.424	0.000
E14.6 With other specified complications	0.573	0.427	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.573	0.427	0.000
D64 Other anaemias	0.572	0.428	0.000
H34.1 Central retinal artery occlusion	0.572	0.428	0.000
J32.9 Chronic sinusitis, unspecified	0.000	0.429	0.571
E27.4 Other and unspecified adrenocortical insufficiency	0.571	0.429	0.000
H34.2 Other retinal artery occlusions	0.570	0.430	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.431	0.569
Q63.1 Lobulated, fused and horseshoe kidney	0.569	0.431	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.569	0.431	0.000
E07.1 Dyshormogenetic goitre	0.568	0.432	0.000
E07.0 Hypersecretion of calcitonin	0.568	0.432	0.000
E13 Other specified diabetes mellitus	0.567	0.432	0.000
M18 Arthrosis of first carpometacarpal joint	0.567	0.433	0.000
H35.7 Separation of retinal layers	0.567	0.433	0.000
D83.9 Common variable immunodeficiency, unspecified	0.567	0.433	0.000
Q40.2 Other specified congenital malformations of stomach	0.566	0.434	0.000
Q63.8 Other specified congenital malformations of kidney	0.565	0.435	0.000
Q63.3 Hyperplastic and giant kidney	0.565	0.435	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.563	0.436	0.001
M15-M19 Arthrosis	0.562	0.438	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.562	0.438	0.000
M14.6 Neuropathic arthropathy	0.000	0.440	0.560
D58 Other hereditary haemolytic anaemias	0.560	0.440	0.000
H43.0 Vitreous prolapse	0.556	0.444	0.000
N03.8 Other	0.556	0.444	0.000
D61.9 Aplastic anaemia, unspecified	0.552	0.448	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.550	0.450	0.000
Q75 Other congenital malformations of skull and face bones	0.550	0.450	0.000
Q73 Reduction defects of unspecified limb	0.550	0.450	0.000
Q72 Reduction defects of lower limb	0.550	0.450	0.000
Q71 Reduction defects of upper limb	0.550	0.450	0.000
Q69 Polydactyly	0.550	0.450	0.000
E27.8 Other specified disorders of adrenal gland	0.549	0.450	0.000
E23.6 Other disorders of pituitary gland	0.549	0.451	0.000
E06.3 Autoimmune thyroiditis	0.548	0.452	0.000
H05.4 Enophthalmos	0.547	0.453	0.000
Q34 Other congenital malformations of respiratory system	0.544	0.456	0.000
Q33 Congenital malformations of lung	0.544	0.456	0.000
Q32 Congenital malformations of trachea and bronchus	0.544	0.456	0.000
Q30 Congenital malformations of nose	0.544	0.456	0.000
P10-P15 Birth trauma	0.544	0.456	0.000
E24.9 Cushing's syndrome, unspecified	0.543	0.457	0.000
E29.9 Testicular dysfunction, unspecified	0.543	0.457	0.000
E29.8 Other testicular dysfunction	0.543	0.457	0.000
E29.0 Testicular hyperfunction	0.543	0.457	0.000
N02.3 Diffuse mesangial proliferative glomerulonephritis	0.542	0.458	0.000
Q39.6 Diverticulum of oesophagus	0.542	0.458	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.540	0.460	0.000
E31.9 Polyglandular dysfunction, unspecified	0.540	0.460	0.000
E31.8 Other polyglandular dysfunction	0.540	0.460	0.000
E31.1 Polyglandular hyperfunction	0.540	0.460	0.000
Q05.9 Spina bifida, unspecified	0.540	0.460	0.000
D83.8 Other common variable immunodeficiencies	0.536	0.464	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.536	0.464	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.536	0.464	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.536	0.464	0.000
Q50-Q56 Congenital malformations of genital organs	0.535	0.465	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations