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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs73729108
log Bayes Factor = 17.2585
Chromosome 6   position 32,514,607  (GRCh37) Explore rs73729108 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.001 0.999
M06.9 Rheumatoid arthritis, unspecified
0.000 0.003 0.997
E03 Other hypothyroidism
0.000 0.003 0.997
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.004 0.996
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.005 0.995
E00-E07 Disorders of thyroid gland
0.000 0.005 0.995
# Top node
0.010 0.006 0.984
J45 Asthma
0.000 0.006 0.993
K90 Intestinal malabsorption
0.000 0.007 0.993
K90-K93 Other diseases of the digestive system
0.000 0.009 0.991
J40-J47 Chronic lower respiratory diseases
0.001 0.010 0.989
Chapter XI Diseases of the digestive system
0.000 0.010 0.990
Chapter X Diseases of the respiratory system
0.003 0.011 0.986
Chapter IV Endocrine, nutritional and metabolic diseases
0.001 0.012 0.987
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.001 0.017 0.982
K20-K31 Diseases of oesophagus, stomach and duodenum
0.000 0.020 0.980
D60-D64 Aplastic and other anaemias
0.000 0.023 0.976
Chapter II Neoplasms
0.000 0.025 0.975
C44 Other malignant neoplasms of skin
0.000 0.027 0.973
D64 Other anaemias
0.000 0.027 0.972
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.027 0.973
D64.9 Anaemia, unspecified
0.000 0.030 0.970
C44.3 Skin of other and unspecified parts of face
0.000 0.033 0.967
K29 Gastritis and duodenitis
0.000 0.037 0.963
K29.8 Duodenitis
0.000 0.042 0.958
J44 Other chronic obstructive pulmonary disease
0.000 0.058 0.942
J00-J06 Acute upper respiratory infections
0.001 0.064 0.936
C44.7 Skin of lower limb, including hip
0.000 0.064 0.936
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.065 0.935
K20 Oesophagitis
0.000 0.069 0.931
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.405 0.078 0.517
J20-J22 Other acute lower respiratory infections
0.001 0.084 0.914
M06 Other rheumatoid arthritis
0.057 0.096 0.847
K22 Other diseases of oesophagus
0.000 0.113 0.887
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.114 0.886
K70-K77 Diseases of liver
0.000 0.123 0.877
E05.9 Thyrotoxicosis, unspecified
0.000 0.123 0.877
J46 Status asthmaticus
0.000 0.126 0.874
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.129 0.871
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.130 0.870
J22 Unspecified acute lower respiratory infection
0.000 0.131 0.869
M05-M14 Inflammatory polyarthropathies
0.268 0.135 0.598
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.138 0.861
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.143 0.857
J02 Acute pharyngitis
0.000 0.144 0.856
K29.4 Chronic atrophic gastritis
0.000 0.147 0.853
D00-D09 In situ neoplasms
0.000 0.149 0.851
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.154 0.846
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.000 0.159 0.841
K22.1 Ulcer of oesophagus
0.000 0.169 0.831
D37-D48 Neoplasms of uncertain or unknown behaviour
0.000 0.177 0.823
D06 Carcinoma in situ of cervix uteri
0.000 0.179 0.821
K22.2 Oesophageal obstruction
0.000 0.182 0.818
C44.0 Skin of lip
0.000 0.184 0.816
E06 Thyroiditis
0.000 0.184 0.816
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.000 0.184 0.816
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.185 0.814
C44.4 Skin of scalp and neck
0.000 0.187 0.813
E50-E64 Other nutritional deficiencies
0.001 0.187 0.812
K26 Duodenal ulcer
0.000 0.190 0.810
M80-M85 Disorders of bone density and structure
0.326 0.194 0.480
D06.9 Cervix, unspecified
0.000 0.200 0.800
J02.9 Acute pharyngitis, unspecified
0.000 0.201 0.799
C51-C58 Malignant neoplasms of female genital organs
0.000 0.201 0.799
K70 Alcoholic liver disease
0.000 0.201 0.799
K27 Peptic ulcer, site unspecified
0.000 0.204 0.796
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.205 0.795
Z85 Personal history of malignant neoplasm
0.000 0.208 0.792
E10-E14 Diabetes mellitus
0.000 0.209 0.790
D62 Acute posthaemorrhagic anaemia
0.000 0.211 0.789
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.214 0.786
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.000 0.215 0.785
K50-K52 Noninfective enteritis and colitis
0.004 0.224 0.772
D69 Purpura and other haemorrhagic conditions
0.000 0.229 0.771
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.000 0.229 0.771
J03 Acute tonsillitis
0.000 0.232 0.768
K92 Other diseases of digestive system
0.000 0.240 0.760
J44.9 Chronic obstructive pulmonary disease, unspecified
0.000 0.244 0.756
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.246 0.754
M06.0 Seronegative rheumatoid arthritis
0.030 0.251 0.719
K29.5 Chronic gastritis, unspecified
0.000 0.256 0.744
D45 Polycythaemia vera
0.000 0.257 0.743
K51 Ulcerative colitis
0.001 0.257 0.742
E11 Non-insulin-dependent diabetes mellitus
0.000 0.259 0.741
E20-E35 Disorders of other endocrine glands
0.001 0.265 0.735
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.265 0.735
K70.9 Alcoholic liver disease, unspecified
0.000 0.265 0.735
E07 Other disorders of thyroid
0.000 0.267 0.733
D69.6 Thrombocytopenia, unspecified
0.000 0.270 0.730
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.000 0.270 0.730
C44.1 Skin of eyelid, including canthus
0.000 0.271 0.729
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.271 0.729
E11.3 With ophthalmic complications
0.000 0.273 0.726
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.276 0.723
C64-C68 Malignant neoplasms of urinary tract
0.000 0.277 0.723
D75 Other diseases of blood and blood-forming organs
0.000 0.279 0.721
K29.1 Other acute gastritis
0.000 0.282 0.718
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.285 0.715
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.285 0.715
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.285 0.715
E03.5 Myxoedema coma
0.000 0.285 0.714
E03.4 Atrophy of thyroid (acquired)
0.000 0.285 0.714
E03.3 Postinfectious hypothyroidism
0.000 0.285 0.714
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.285 0.714
E03.1 Congenital hypothyroidism without goitre
0.000 0.285 0.714
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.285 0.714
D80-D89 Certain disorders involving the immune mechanism
0.001 0.286 0.714
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.287 0.713
E00 Congenital iodine-deficiency syndrome
0.000 0.287 0.713
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.287 0.713
Chapter XVI Certain conditions originating in the perinatal period
0.007 0.287 0.706
J45.8 Mixed asthma
0.000 0.287 0.712
J45.1 Nonallergic asthma
0.000 0.287 0.712
K90.8 Other intestinal malabsorption
0.000 0.288 0.712
K90.3 Pancreatic steatorrhoea
0.000 0.288 0.712
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.288 0.712
K90.1 Tropical sprue
0.000 0.288 0.712
J06 Acute upper respiratory infections of multiple and unspecified sites
0.000 0.289 0.710
K51.9 Ulcerative colitis, unspecified
0.000 0.289 0.711
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.290 0.710
C81 Hodgkin's disease
0.000 0.290 0.710
J41 Simple and mucopurulent chronic bronchitis
0.001 0.290 0.709
K22.9 Disease of oesophagus, unspecified
0.000 0.292 0.708
J01 Acute sinusitis
0.000 0.292 0.708
J90-J94 Other diseases of pleura
0.001 0.292 0.707
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.000 0.294 0.706
E55 Vitamin D deficiency
0.000 0.295 0.704
K35-K38 Diseases of appendix
0.000 0.296 0.704
C44.9 Malignant neoplasm of skin, unspecified
0.000 0.297 0.703
K28 Gastrojejunal ulcer
0.000 0.297 0.702
K23 Disorders of oesophagus in diseases classified elsewhere
0.000 0.297 0.702
C73 Malignant neoplasm of thyroid gland
0.000 0.298 0.702
C53 Malignant neoplasm of cervix uteri
0.000 0.298 0.701
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.002 0.299 0.699
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.300 0.700
J04 Acute laryngitis and tracheitis
0.000 0.300 0.699
C40-C41 Malignant neoplasms of bone and articular cartilage
0.000 0.301 0.699
D55-D59 Haemolytic anaemias
0.001 0.301 0.698
C44.8 Overlapping lesion of skin
0.000 0.302 0.698
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.000 0.302 0.698
D64.8 Other specified anaemias
0.000 0.303 0.697
D64.4 Congenital dyserythropoietic anaemia
0.000 0.303 0.697
D64.3 Other sideroblastic anaemias
0.000 0.303 0.697
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.303 0.697
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.303 0.697
D64.0 Hereditary sideroblastic anaemia
0.000 0.303 0.697
K92.0 Haematemesis
0.000 0.307 0.693
K29.9 Gastroduodenitis, unspecified
0.000 0.309 0.691
K29.2 Alcoholic gastritis
0.000 0.309 0.691
E06.3 Autoimmune thyroiditis
0.000 0.312 0.688
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.000 0.312 0.688
Chapter XXII Codes for special purposes
0.007 0.313 0.680
J45.0 Predominantly allergic asthma
0.000 0.326 0.674
K51.2 Ulcerative (chronic) proctitis
0.001 0.327 0.672
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.001 0.328 0.671
C54 Malignant neoplasm of corpus uteri
0.000 0.329 0.671
E05.8 Other thyrotoxicosis
0.000 0.330 0.670
E05.5 Thyroid crisis or storm
0.000 0.330 0.670
E05.4 Thyrotoxicosis factitia
0.000 0.330 0.670
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.330 0.670
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.330 0.670
K29.3 Chronic superficial gastritis
0.000 0.335 0.665
K26.4 Chronic or unspecified with haemorrhage
0.000 0.335 0.665
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.000 0.336 0.664
K72 Hepatic failure, not elsewhere classified
0.000 0.337 0.663
C44.5 Skin of trunk
0.000 0.338 0.662
E03.8 Other specified hypothyroidism
0.000 0.340 0.660
J95-J99 Other diseases of the respiratory system
0.002 0.341 0.658
M60-M63 Disorders of muscles
0.300 0.343 0.357
J21 Acute bronchiolitis
0.001 0.343 0.655
M00-M03 Infectious arthropathies
0.304 0.344 0.352
M05 Seropositive rheumatoid arthritis
0.158 0.346 0.496
K51.8 Other ulcerative colitis
0.001 0.348 0.651
J90 Pleural effusion, not elsewhere classified
0.000 0.349 0.651
C09 Malignant neoplasm of tonsil
0.000 0.349 0.651
M06.8 Other specified rheumatoid arthritis
0.041 0.352 0.607
M06.4 Inflammatory polyarthropathy
0.041 0.352 0.607
M06.3 Rheumatoid nodule
0.041 0.352 0.607
M06.2 Rheumatoid bursitis
0.041 0.352 0.607
M06.1 Adult-onset Still's disease
0.041 0.352 0.607
M91-M94 Chondropathies
0.264 0.352 0.384
J03.9 Acute tonsillitis, unspecified
0.000 0.353 0.647
K76 Other diseases of liver
0.000 0.353 0.647
J00 Acute nasopharyngitis [common cold]
0.000 0.353 0.646
D75.1 Secondary polycythaemia
0.000 0.353 0.647
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.353 0.647
Chapter I Certain infectious and parasitic diseases
0.001 0.354 0.645
M81 Osteoporosis without pathological fracture
0.174 0.354 0.472
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.355 0.645
C67 Malignant neoplasm of bladder
0.000 0.355 0.645
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.356 0.644
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.357 0.642
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.014 0.358 0.628
K22.3 Perforation of oesophagus
0.000 0.364 0.636
K92.1 Melaena
0.000 0.364 0.636
E11.4 With neurological complications
0.000 0.364 0.636
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.001 0.364 0.635
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.364 0.635
C95 Leukaemia of unspecified cell type
0.000 0.364 0.635
C94 Other leukaemias of specified cell type
0.000 0.364 0.635
C93 Monocytic leukaemia
0.000 0.364 0.635
C86 Other specified types of T/NK-cell lymphoma
0.000 0.364 0.635
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.364 0.635
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.365 0.635
K90.9 Intestinal malabsorption, unspecified
0.000 0.367 0.632
C92 Myeloid leukaemia
0.000 0.368 0.632
C53.9 Cervix uteri, unspecified
0.000 0.368 0.632
K77 Liver disorders in diseases classified elsewhere
0.000 0.371 0.629
K73 Chronic hepatitis, not elsewhere classified
0.000 0.371 0.629
K71 Toxic liver disease
0.000 0.371 0.629
E55.9 Vitamin D deficiency, unspecified
0.000 0.373 0.627
D68 Other coagulation defects
0.000 0.373 0.627
Z85.4 Personal history of malignant neoplasm of genital organs
0.000 0.373 0.627
Chapter XII Diseases of the skin and subcutaneous tissue
0.001 0.375 0.624
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.000 0.377 0.622
M14 Arthropathies in other diseases classified elsewhere
0.192 0.379 0.429
M12 Other specific arthropathies
0.192 0.379 0.429
M09 Juvenile arthritis in diseases classified elsewhere
0.192 0.379 0.429
M08 Juvenile arthritis
0.192 0.379 0.429
K22.8 Other specified diseases of oesophagus
0.000 0.380 0.620
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.304 0.380 0.316
M86-M90 Other osteopathies
0.346 0.380 0.274
J20 Acute bronchitis
0.001 0.381 0.618
B35-B49 Mycoses
0.000 0.382 0.618
D67 Hereditary factor IX deficiency
0.000 0.382 0.617
D66 Hereditary factor VIII deficiency
0.000 0.382 0.617
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.382 0.617
D05 Carcinoma in situ of breast
0.000 0.385 0.615
C44.2 Skin of ear and external auricular canal
0.000 0.386 0.614
J02.8 Acute pharyngitis due to other specified organisms
0.000 0.386 0.614
J02.0 Streptococcal pharyngitis
0.000 0.386 0.614
K75 Other inflammatory liver diseases
0.000 0.386 0.614
K22.4 Dyskinesia of oesophagus
0.000 0.386 0.614
D70 Agranulocytosis
0.000 0.387 0.613
K31 Other diseases of stomach and duodenum
0.000 0.389 0.611
C91 Lymphoid leukaemia
0.000 0.389 0.611
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.000 0.389 0.611
D02 Carcinoma in situ of middle ear and respiratory system
0.000 0.390 0.610
D01 Carcinoma in situ of other and unspecified digestive organs
0.000 0.390 0.610
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.000 0.390 0.610
C90 Multiple myeloma and malignant plasma cell neoplasms
0.000 0.391 0.609
M07 Psoriatic and enteropathic arthropathies
0.179 0.391 0.430
C60-C63 Malignant neoplasms of male genital organs
0.000 0.396 0.604
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.000 0.396 0.604
K70.4 Alcoholic hepatic failure
0.000 0.397 0.602
M11 Other crystal arthropathies
0.187 0.398 0.414
B37 Candidiasis
0.000 0.399 0.600
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.402 0.598
D46 Myelodysplastic syndromes
0.000 0.402 0.598
C88 Malignant immunoproliferative diseases
0.000 0.404 0.596
M40-M43 Deforming dorsopathies
0.273 0.405 0.322
Z85.5 Personal history of malignant neoplasm of urinary tract
0.000 0.406 0.594
C67.9 Bladder, unspecified
0.000 0.408 0.592
K65-K67 Diseases of peritoneum
0.000 0.408 0.592
E53 Deficiency of other B group vitamins
0.000 0.409 0.590
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.000 0.410 0.590
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.000 0.410 0.590
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.000 0.410 0.590
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.000 0.410 0.590
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.000 0.410 0.590
K70.3 Alcoholic cirrhosis of liver
0.000 0.410 0.590
D06.7 Other parts of cervix
0.000 0.411 0.589
D06.1 Exocervix
0.000 0.411 0.589
D06.0 Endocervix
0.000 0.411 0.589
J60-J70 Lung diseases due to external agents
0.002 0.412 0.586
E40-E46 Malnutrition
0.001 0.414 0.585
C02 Malignant neoplasm of other and unspecified parts of tongue
0.000 0.414 0.585
E06.9 Thyroiditis, unspecified
0.000 0.415 0.585
E06.5 Other chronic thyroiditis
0.000 0.415 0.585
E06.4 Drug-induced thyroiditis
0.000 0.415 0.585
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.415 0.585
E06.1 Subacute thyroiditis
0.000 0.415 0.585
E06.0 Acute thyroiditis
0.000 0.415 0.585
C75 Malignant neoplasm of other endocrine glands and related structures
0.000 0.415 0.585
C74 Malignant neoplasm of adrenal gland
0.000 0.415 0.585
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.000 0.415 0.585
E29 Testicular dysfunction
0.000 0.416 0.584
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.000 0.416 0.584
D74 Methaemoglobinaemia
0.000 0.416 0.584
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.000 0.416 0.584
D71 Functional disorders of polymorphonuclear neutrophils
0.000 0.416 0.584
E21.0 Primary hyperparathyroidism
0.000 0.416 0.584
C81.9 Hodgkin's disease, unspecified
0.000 0.416 0.584
E64 Sequelae of malnutrition and other nutritional deficiencies
0.001 0.417 0.582
E63 Other nutritional deficiencies
0.001 0.417 0.582
E56 Other vitamin deficiencies
0.001 0.417 0.582
E51 Thiamine deficiency
0.001 0.417 0.582
E50 Vitamin A deficiency
0.001 0.417 0.582
E60 Dietary zinc deficiency
0.001 0.417 0.582
E59 Dietary selenium deficiency
0.001 0.417 0.582
E58 Dietary calcium deficiency
0.001 0.417 0.582
E54 Ascorbic acid deficiency
0.001 0.417 0.582
E52 Niacin deficiency [pellagra]
0.001 0.417 0.582
E07.9 Disorder of thyroid, unspecified
0.000 0.417 0.583
B37.8 Candidiasis of other sites
0.000 0.419 0.581
D72 Other disorders of white blood cells
0.000 0.419 0.581
K26.6 Chronic or unspecified with both haemorrhage and perforation
0.000 0.419 0.581
K26.2 Acute with both haemorrhage and perforation
0.000 0.419 0.581
K26.1 Acute with perforation
0.000 0.419 0.581
K26.0 Acute with haemorrhage
0.000 0.419 0.581
K74 Fibrosis and cirrhosis of liver
0.000 0.420 0.580
C54.1 Endometrium
0.000 0.420 0.580
D07 Carcinoma in situ of other and unspecified genital organs
0.000 0.421 0.579
D47.2 Monoclonal gammopathy
0.000 0.422 0.578
M83 Adult osteomalacia
0.234 0.422 0.344
M82 Osteoporosis in diseases classified elsewhere
0.234 0.422 0.344
D50-D53 Nutritional anaemias
0.000 0.423 0.576
C57 Malignant neoplasm of other and unspecified female genital organs
0.000 0.427 0.573
C58 Malignant neoplasm of placenta
0.000 0.427 0.573
C55 Malignant neoplasm of uterus, part unspecified
0.000 0.427 0.573
C52 Malignant neoplasm of vagina
0.000 0.427 0.573
K70.2 Alcoholic fibrosis and sclerosis of liver
0.000 0.427 0.573
K70.0 Alcoholic fatty liver
0.000 0.427 0.573
K27.7 Chronic without haemorrhage or perforation
0.000 0.429 0.571
K27.6 Chronic or unspecified with both haemorrhage and perforation
0.000 0.429 0.571
K27.5 Chronic or unspecified with perforation
0.000 0.429 0.571
K27.4 Chronic or unspecified with haemorrhage
0.000 0.429 0.571
K27.3 Acute without haemorrhage or perforation
0.000 0.429 0.571
K27.2 Acute with both haemorrhage and perforation
0.000 0.429 0.571
K27.1 Acute with perforation
0.000 0.429 0.571
K27.0 Acute with haemorrhage
0.000 0.429 0.571
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.000 0.430 0.570
C82.6 Cutaneous follicle centre lymphoma
0.000 0.430 0.570
C82.5 Diffuse follicle centre lymphoma
0.000 0.430 0.570
C82.4 Follicular lymphoma grade IIIb
0.000 0.430 0.570
C82.3 Follicular lymphoma grade IIIa
0.000 0.430 0.570
C82.2 Large cell, follicular
0.000 0.430 0.570
C82.1 Mixed small cleaved and large cell, follicular
0.000 0.430 0.570
C82.0 Small cleaved cell, follicular
0.000 0.430 0.570
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.001 0.431 0.568
C85.1 B-cell lymphoma, unspecified
0.000 0.431 0.569
Z85.0 Personal history of malignant neoplasm of digestive organs
0.000 0.432 0.568
E12 Malnutrition-related diabetes mellitus
0.000 0.433 0.567
J95 Postprocedural respiratory disorders, not elsewhere classified
0.001 0.436 0.564
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.000 0.437 0.563
C13 Malignant neoplasm of hypopharynx
0.000 0.437 0.563
C11 Malignant neoplasm of nasopharynx
0.000 0.437 0.563
C10 Malignant neoplasm of oropharynx
0.000 0.437 0.563
C08 Malignant neoplasm of other and unspecified major salivary glands
0.000 0.437 0.563
C06 Malignant neoplasm of other and unspecified parts of mouth
0.000 0.437 0.563
C05 Malignant neoplasm of palate
0.000 0.437 0.563
C04 Malignant neoplasm of floor of mouth
0.000 0.437 0.563
C03 Malignant neoplasm of gum
0.000 0.437 0.563
C00 Malignant neoplasm of lip
0.000 0.437 0.563
C12 Malignant neoplasm of pyriform sinus
0.000 0.437 0.563
C07 Malignant neoplasm of parotid gland
0.000 0.437 0.563
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome
0.000 0.437 0.563
E04 Other non-toxic goitre
0.000 0.437 0.563
D68.9 Coagulation defect, unspecified
0.000 0.438 0.562
K76.9 Liver disease, unspecified
0.000 0.440 0.560
D09 Carcinoma in situ of other and unspecified sites
0.000 0.441 0.559
C51 Malignant neoplasm of vulva
0.000 0.441 0.559
K40-K46 Hernia
0.000 0.441 0.559
K29.0 Acute haemorrhagic gastritis
0.000 0.443 0.556
E23 Hypofunction and other disorders of pituitary gland
0.000 0.444 0.555
D61 Other aplastic anaemias
0.001 0.445 0.554
C09.9 Tonsil, unspecified
0.000 0.446 0.554
D69.9 Haemorrhagic condition, unspecified
0.000 0.447 0.553
D69.8 Other specified haemorrhagic conditions
0.000 0.447 0.553
D69.4 Other primary thrombocytopenia
0.000 0.447 0.553
D69.2 Other nonthrombocytopenic purpura
0.000 0.447 0.553
D69.1 Qualitative platelet defects
0.000 0.447 0.553
D69.0 Allergic purpura
0.000 0.447 0.553
D86 Sarcoidosis
0.000 0.447 0.553
E11.5 With peripheral circulatory complications
0.000 0.447 0.553
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.000 0.448 0.551
K26.7 Chronic without haemorrhage or perforation
0.000 0.449 0.551
J03.8 Acute tonsillitis due to other specified organisms
0.000 0.449 0.550
J03.0 Streptococcal tonsillitis
0.000 0.449 0.550
K70.1 Alcoholic hepatitis
0.000 0.449 0.551
J06.9 Acute upper respiratory infection, unspecified
0.000 0.451 0.549
M85 Other disorders of bone density and structure
0.240 0.451 0.309
M65-M68 Disorders of synovium and tendon
0.366 0.452 0.182
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.000 0.452 0.548
K26.5 Chronic or unspecified with perforation
0.000 0.453 0.547
K92.8 Other specified diseases of digestive system
0.000 0.455 0.545
M10 Gout
0.156 0.455 0.389
D75.8 Other specified diseases of blood and blood-forming organs
0.000 0.455 0.545
J01.9 Acute sinusitis, unspecified
0.000 0.456 0.544
Z85.6 Personal history of leukaemia
0.000 0.456 0.544
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.458 0.542
M80 Osteoporosis with pathological fracture
0.224 0.462 0.315
M45-M49 Spondylopathies
0.288 0.462 0.251
L40-L45 Papulosquamous disorders
0.000 0.462 0.537
K44 Diaphragmatic hernia
0.000 0.462 0.538
K22.0 Achalasia of cardia
0.000 0.462 0.537
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.001 0.463 0.537
M06.08 Seronegative rheumatoid arthritis (Other)
0.022 0.463 0.515
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.022 0.463 0.515
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.022 0.463 0.515
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.022 0.463 0.515
M06.04 Seronegative rheumatoid arthritis (Hand)
0.022 0.463 0.515
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.022 0.463 0.515
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.022 0.463 0.515
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.022 0.463 0.515
E61 Deficiency of other nutrient elements
0.001 0.463 0.536
C44.6 Skin of upper limb, including shoulder
0.000 0.464 0.536
D47.3 Essential (haemorrhagic) thrombocythaemia
0.000 0.464 0.536
C01 Malignant neoplasm of base of tongue
0.000 0.464 0.535
K22.5 Diverticulum of oesophagus, acquired
0.000 0.465 0.535
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.466 0.534
E11.6 With other specified complications
0.000 0.467 0.533
K51.1 Ulcerative (chronic) ileocolitis
0.001 0.467 0.532
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.021 0.468 0.512
D63.8 Anaemia in other chronic diseases classified elsewhere
0.000 0.469 0.531
E11.8 With unspecified complications
0.000 0.469 0.531
E11.7 With multiple complications
0.000 0.469 0.531
D63.0 Anaemia in neoplastic disease
0.000 0.470 0.530
J04.0 Acute laryngitis
0.000 0.470 0.529
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.471 0.529
M81.9 Osteoporosis, unspecified
0.059 0.471 0.470
K76.6 Portal hypertension
0.000 0.472 0.528
E35 Disorders of endocrine glands in diseases classified elsewhere
0.001 0.473 0.527
E32 Diseases of thymus
0.001 0.473 0.527
E31 Polyglandular dysfunction
0.001 0.473 0.527
E30 Disorders of puberty, not elsewhere classified
0.001 0.473 0.527
E26 Hyperaldosteronism
0.001 0.473 0.527
E25 Adrenogenital disorders
0.001 0.473 0.527
E20 Hypoparathyroidism
0.001 0.473 0.527
K37 Unspecified appendicitis
0.000 0.473 0.527
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.473 0.527
C85.0 Lymphosarcoma
0.000 0.473 0.527
E07.1 Dyshormogenetic goitre
0.000 0.474 0.526
E07.0 Hypersecretion of calcitonin
0.000 0.474 0.526
E13 Other specified diabetes mellitus
0.000 0.476 0.523
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.000 0.477 0.523
D04 Carcinoma in situ of skin
0.000 0.478 0.522
E14 Unspecified diabetes mellitus
0.000 0.480 0.520
D63.1 Anaemia in other chronic diseases classified elsewhere
0.000 0.481 0.519
M84 Disorders of continuity of bone
0.294 0.482 0.224
C68 Malignant neoplasm of other and unspecified urinary organs
0.000 0.482 0.518
C66 Malignant neoplasm of ureter
0.000 0.482 0.518
Z85.9 Personal history of malignant neoplasm, unspecified
0.000 0.482 0.518
E27 Other disorders of adrenal gland
0.001 0.483 0.517
D75.2 Essential thrombocytosis
0.000 0.483 0.517
D75.0 Familial erythrocytosis
0.000 0.483 0.517
C97 Malignant neoplasms of independent (primary) multiple sites
0.000 0.486 0.514
L57.0 Actinic keratosis
0.000 0.487 0.512
D84 Other immunodeficiencies
0.001 0.488 0.512
D83 Common variable immunodeficiency
0.001 0.488 0.512
D82 Immunodeficiency associated with other major defects
0.001 0.488 0.512
D81 Combined immunodeficiencies
0.001 0.488 0.512
D80 Immunodeficiency with predominantly antibody defects
0.001 0.488 0.512
J94 Other pleural conditions
0.001 0.488 0.511
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.489 0.511
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.489 0.511
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.489 0.511
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.489 0.511
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.489 0.511
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.489 0.511
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.489 0.511
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.489 0.511
P90-P96 Other disorders originating in the perinatal period
0.005 0.489 0.506
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn
0.005 0.489 0.506
P75-P78 Digestive system disorders of fetus and newborn
0.005 0.489 0.506
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn
0.005 0.489 0.506
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn
0.005 0.489 0.506
P35-P39 Infections specific to the perinatal period
0.005 0.489 0.506
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period
0.005 0.489 0.506
P10-P15 Birth trauma
0.005 0.489 0.506
P05-P08 Disorders related to length of gestation and fetal growth
0.005 0.489 0.506
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery
0.005 0.489 0.506
M13 Other arthritis
0.252 0.490 0.258
J06.8 Other acute upper respiratory infections of multiple sites
0.000 0.490 0.509
J06.0 Acute laryngopharyngitis
0.000 0.490 0.509
C67.4 Posterior wall of bladder
0.000 0.491 0.509
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.491 0.509
K93.1 Megacolon in Chagas' disease
0.000 0.491 0.509
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.491 0.509
C81.7 Other Hodgkin's disease
0.000 0.491 0.509
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.000 0.491 0.509
C81.3 Lymphocytic depletion
0.000 0.491 0.509
C81.2 Mixed cellularity
0.000 0.491 0.509
C81.1 Nodular sclerosis
0.000 0.491 0.509
C81.0 Lymphocytic predominance
0.000 0.491 0.509
J41.8 Mixed simple and mucopurulent chronic bronchitis
0.001 0.491 0.508
J41.1 Mucopurulent chronic bronchitis
0.001 0.491 0.508
J41.0 Simple chronic bronchitis
0.001 0.491 0.508
K72.9 Hepatic failure, unspecified
0.000 0.491 0.509
J01.8 Other acute sinusitis
0.000 0.492 0.507
J01.4 Acute pansinusitis
0.000 0.492 0.507
J01.3 Acute sphenoidal sinusitis
0.000 0.492 0.507
J01.2 Acute ethmoidal sinusitis
0.000 0.492 0.507
J01.1 Acute frontal sinusitis
0.000 0.492 0.507
J01.0 Acute maxillary sinusitis
0.000 0.492 0.507
E11.0 With coma
0.000 0.493 0.507
K26.3 Acute without haemorrhage or perforation
0.000 0.493 0.507
D75.9 Disease of blood and blood-forming organs, unspecified
0.000 0.494 0.506
E55.0 Rickets, active
0.000 0.495 0.505
K36 Other appendicitis
0.000 0.495 0.505
K23.8 Disorders of oesophagus in other diseases classified elsewhere
0.000 0.496 0.504
K23.1 Megaoesophagus in Chagas' disease
0.000 0.496 0.504
K23.0 Tuberculous oesophagitis
0.000 0.496 0.504
K28.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.000 0.496 0.504
K28.7 Chronic without haemorrhage or perforation
0.000 0.496 0.504
K28.6 Chronic or unspecified with both haemorrhage and perforation
0.000 0.496 0.504
K28.5 Chronic or unspecified with perforation
0.000 0.496 0.504

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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