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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7383433
log Bayes Factor = 28.6658
Chromosome 6   position 32,778,531  (GRCh37) Explore rs7383433 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
C44 Other malignant neoplasms of skin
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.001 0.999
L40 Psoriasis
0.000 0.001 0.999
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
E20-E35 Disorders of other endocrine glands
0.000 0.001 0.999
C44.7 Skin of lower limb, including hip
0.000 0.001 0.999
C44.6 Skin of upper limb, including shoulder
0.000 0.001 0.999
E00-E07 Disorders of thyroid gland
0.000 0.002 0.998
E10.3 With ophthalmic complications
0.000 0.002 0.998
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.002 0.998
L40.9 Psoriasis, unspecified
0.000 0.003 0.997
C44.3 Skin of other and unspecified parts of face
0.000 0.004 0.996
E05.9 Thyrotoxicosis, unspecified
0.000 0.006 0.994
E23 Hypofunction and other disorders of pituitary gland
0.000 0.014 0.986
C44.4 Skin of scalp and neck
0.000 0.022 0.978
E27 Other disorders of adrenal gland
0.000 0.031 0.969
L57.0 Actinic keratosis
0.000 0.032 0.968
G35-G37 Demyelinating diseases of the central nervous system
0.965 0.035 0.000
G37 Other demyelinating diseases of central nervous system
0.954 0.046 0.000
E23.7 Disorder of pituitary gland, unspecified
0.000 0.060 0.940
C44.2 Skin of ear and external auricular canal
0.000 0.063 0.937
G37.9 Demyelinating disease of central nervous system, unspecified
0.932 0.068 0.000
J45.9 Asthma, unspecified
0.927 0.073 0.000
E23.6 Other disorders of pituitary gland
0.000 0.074 0.926
E27.1 Primary adrenocortical insufficiency
0.000 0.074 0.926
E10.2 With renal complications
0.000 0.082 0.918
E10.9 Without complications
0.000 0.082 0.918
E10.5 With peripheral circulatory complications
0.000 0.089 0.911
E24 Cushing's syndrome
0.000 0.107 0.893
E10.1 With ketoacidosis
0.000 0.112 0.888
G37.8 Other specified demyelinating diseases of central nervous system
0.875 0.125 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.157 0.843
L40-L45 Papulosquamous disorders
0.000 0.160 0.840
E28 Ovarian dysfunction
0.000 0.170 0.830
J45 Asthma
0.829 0.171 0.000
L40.1 Generalised pustular psoriasis
0.000 0.171 0.829
L40.3 Pustulosis palmaris et plantaris
0.000 0.171 0.829
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.175 0.825
J45.0 Predominantly allergic asthma
0.803 0.197 0.000
C44.0 Skin of lip
0.000 0.203 0.797
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.204 0.796
E83.1 Disorders of iron metabolism
0.795 0.205 0.000
E23.0 Hypopituitarism
0.000 0.211 0.789
G36 Other acute disseminated demyelination
0.787 0.213 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.213 0.787
E10.0 With coma
0.000 0.220 0.780
E10.4 With neurological complications
0.000 0.223 0.777
E06 Thyroiditis
0.000 0.228 0.772
L40.4 Guttate psoriasis
0.000 0.230 0.770
E13 Other specified diabetes mellitus
0.000 0.237 0.763
M07.3 Other psoriatic arthropathies
0.000 0.246 0.754
E29 Testicular dysfunction
0.000 0.247 0.753
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.250 0.750
L40.0 Psoriasis vulgaris
0.000 0.252 0.748
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.252 0.748
E24.0 Pituitary-dependent Cushing's disease
0.000 0.261 0.739
E26 Hyperaldosteronism
0.000 0.262 0.738
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.265 0.735
E24.2 Drug-induced Cushing's syndrome
0.000 0.268 0.732
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.272 0.728
L43 Lichen planus
0.000 0.274 0.726
C44.8 Overlapping lesion of skin
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.716
L40.2 Acrodermatitis continua
0.000 0.283 0.716
E05.5 Thyroid crisis or storm
0.000 0.284 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.284 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.284 0.716
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.284 0.716
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.284 0.716
E32 Diseases of thymus
0.000 0.284 0.716
E31 Polyglandular dysfunction
0.000 0.284 0.716
E30 Disorders of puberty, not elsewhere classified
0.000 0.284 0.716
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.284 0.716
E00 Congenital iodine-deficiency syndrome
0.000 0.284 0.716
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.293 0.707
E23.1 Drug-induced hypopituitarism
0.000 0.293 0.707
E24.9 Cushing's syndrome, unspecified
0.000 0.301 0.698
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.305 0.695
E28.2 Polycystic ovarian syndrome
0.000 0.305 0.695
E27.5 Adrenomedullary hyperfunction
0.000 0.305 0.695
E27.0 Other adrenocortical overactivity
0.000 0.305 0.695
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.307 0.693
E27.9 Disorder of adrenal gland, unspecified
0.000 0.313 0.687
G37.5 Concentric sclerosis [Balo]
0.684 0.316 0.000
G37.4 Subacute necrotising myelitis
0.684 0.316 0.000
G37.2 Central pontine myelinolysis
0.684 0.316 0.000
G37.1 Central demyelination of corpus callosum
0.684 0.316 0.000
G37.0 Diffuse sclerosis
0.684 0.316 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.318 0.682
E11 Non-insulin-dependent diabetes mellitus
0.000 0.319 0.681
E21.3 Hyperparathyroidism, unspecified
0.000 0.319 0.681
E70-E90 Metabolic disorders
0.000 0.324 0.676
E25 Adrenogenital disorders
0.000 0.327 0.673
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.330 0.670
E34 Other endocrine disorders
0.000 0.332 0.668
E06.3 Autoimmune thyroiditis
0.000 0.334 0.666
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.334 0.666
E05.8 Other thyrotoxicosis
0.000 0.337 0.663
E65-E68 Obesity and other hyperalimentation
0.000 0.339 0.661
G36.0 Neuromyelitis optica [Devic]
0.660 0.340 0.000
E10.6 With other specified complications
0.000 0.343 0.657
E11.3 With ophthalmic complications
0.000 0.346 0.654
E40-E46 Malnutrition
0.000 0.351 0.649
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.354 0.646
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.356 0.644
E24.8 Other Cushing's syndrome
0.000 0.360 0.640
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.360 0.640
E24.3 Ectopic ACTH syndrome
0.000 0.360 0.640
E24.1 Nelson's syndrome
0.000 0.360 0.640
E23.2 Diabetes insipidus
0.000 0.366 0.634
J45.8 Mixed asthma
0.634 0.366 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.370 0.629
L43.9 Lichen planus, unspecified
0.000 0.377 0.623
E27.8 Other specified disorders of adrenal gland
0.000 0.379 0.621
E28.3 Primary ovarian failure
0.000 0.380 0.620
J45.1 Nonallergic asthma
0.618 0.382 0.000
E89.0 Postprocedural hypothyroidism
0.000 0.387 0.613
E27.2 Addisonian crisis
0.000 0.389 0.611
E20 Hypoparathyroidism
0.000 0.390 0.610
L44 Other papulosquamous disorders
0.000 0.397 0.602
L41 Parapsoriasis
0.000 0.397 0.602
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.397 0.602
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.401 0.598
E78.2 Mixed hyperlipidaemia
0.000 0.402 0.598
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.596 0.403 0.000
E28.9 Ovarian dysfunction, unspecified
0.000 0.405 0.595
E28.8 Other ovarian dysfunction
0.000 0.405 0.595
E28.1 Androgen excess
0.000 0.405 0.595
E28.0 Oestrogen excess
0.000 0.405 0.595
L57.5 Actinic granuloma
0.000 0.408 0.592
L57.3 Poikiloderma of Civatte
0.000 0.408 0.592
L57.2 Cutis rhomboidalis nuchae
0.000 0.408 0.592
L57.1 Actinic reticuloid
0.000 0.408 0.592
E10.8 With unspecified complications
0.000 0.416 0.584
E78.5 Hyperlipidaemia, unspecified
0.000 0.416 0.584
E13.9 Without complications
0.000 0.418 0.582
E29.1 Testicular hypofunction
0.000 0.423 0.577
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.431 0.569
E78.6 Lipoprotein deficiency
0.000 0.432 0.568
E65 Localised adiposity
0.000 0.433 0.567
E06.5 Other chronic thyroiditis
0.000 0.433 0.567
G36.9 Acute disseminated demyelination, unspecified
0.564 0.435 0.000
G36.8 Other specified acute disseminated demyelination
0.564 0.435 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.564 0.435 0.000
E21.4 Other specified disorders of parathyroid gland
0.000 0.436 0.564
E88 Other metabolic disorders
0.000 0.436 0.564
L43.8 Other lichen planus
0.000 0.438 0.562
E13.3 With ophthalmic complications
0.000 0.438 0.562
E21.2 Other hyperparathyroidism
0.000 0.440 0.560
E04 Other non-toxic goitre
0.000 0.445 0.555
E06.4 Drug-induced thyroiditis
0.000 0.446 0.554
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.446 0.554
E06.0 Acute thyroiditis
0.000 0.446 0.554
E06.9 Thyroiditis, unspecified
0.000 0.448 0.552
E26.0 Primary hyperaldosteronism
0.000 0.449 0.551
E11.2 With renal complications
0.000 0.452 0.548
E22 Hyperfunction of pituitary gland
0.000 0.452 0.548
E13.8 With unspecified complications
0.000 0.453 0.547
E13.7 With multiple complications
0.000 0.453 0.547
E13.6 With other specified complications
0.000 0.453 0.547
E13.5 With peripheral circulatory complications
0.000 0.453 0.547
E13.4 With neurological complications
0.000 0.453 0.547
E13.2 With renal complications
0.000 0.453 0.547
E13.1 With ketoacidosis
0.000 0.453 0.547
E13.0 With coma
0.000 0.453 0.547
E34.8 Other specified endocrine disorders
0.000 0.454 0.546
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.455 0.544
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.458 0.542
E11.0 With coma
0.000 0.459 0.541
M07.38 Other psoriatic arthropathies (Other)
0.000 0.459 0.540
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.459 0.540
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.459 0.540
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.459 0.540
E29.9 Testicular dysfunction, unspecified
0.000 0.460 0.540
E29.8 Other testicular dysfunction
0.000 0.460 0.540
E29.0 Testicular hyperfunction
0.000 0.460 0.540
E16 Other disorders of pancreatic internal secretion
0.000 0.467 0.533
E78.1 Pure hyperglyceridaemia
0.000 0.470 0.530
E26.9 Hyperaldosteronism, unspecified
0.000 0.471 0.529
E26.8 Other hyperaldosteronism
0.000 0.471 0.529
E26.1 Secondary hyperaldosteronism
0.000 0.471 0.529
L55 Sunburn
0.000 0.473 0.527
E79 Disorders of purine and pyrimidine metabolism
0.000 0.475 0.525
L40.8 Other psoriasis
0.000 0.477 0.523
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.477 0.522
E15 Nondiabetic hypoglycaemic coma
0.000 0.478 0.522
L43.3 Subacute (active) lichen planus
0.000 0.479 0.520
L43.2 Lichenoid drug reaction
0.000 0.479 0.520
L43.1 Bullous lichen planus
0.000 0.479 0.520
L43.0 Hypertrophic lichen planus
0.000 0.479 0.520
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.480 0.520
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E30.9 Disorder of puberty, unspecified
0.000 0.486 0.513
E30.8 Other disorders of puberty
0.000 0.486 0.513
E30.1 Precocious puberty
0.000 0.486 0.513
E30.0 Delayed puberty
0.000 0.486 0.513
E31.9 Polyglandular dysfunction, unspecified
0.000 0.486 0.513
E31.8 Other polyglandular dysfunction
0.000 0.486 0.513
E31.1 Polyglandular hyperfunction
0.000 0.486 0.513
E31.0 Autoimmune polyglandular failure
0.000 0.486 0.513
E32.9 Disease of thymus, unspecified
0.000 0.486 0.513
E32.8 Other diseases of thymus
0.000 0.486 0.513
E32.1 Abscess of thymus
0.000 0.486 0.513
E32.0 Persistent hyperplasia of thymus
0.000 0.486 0.513
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.486 0.513
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.486 0.513
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.486 0.513
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.487 0.513
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.487 0.513
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.487 0.513
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.487 0.513
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.487 0.513
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.487 0.513
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.487 0.513
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.487 0.513
E89.3 Postprocedural hypopituitarism
0.000 0.488 0.512
L42 Pityriasis rosea
0.000 0.490 0.510
E04.0 Non-toxic diffuse goitre
0.000 0.503 0.497
E84 Cystic fibrosis
0.000 0.505 0.495
E11.7 With multiple complications
0.000 0.512 0.488
E77 Disorders of glycoprotein metabolism
0.000 0.515 0.484
E76 Disorders of glycosaminoglycan metabolism
0.000 0.515 0.484
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.515 0.484
E70 Disorders of aromatic amino-acid metabolism
0.000 0.515 0.484
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.515 0.484
L58 Radiodermatitis
0.000 0.516 0.483
E25.9 Adrenogenital disorder, unspecified
0.000 0.517 0.482
E25.8 Other adrenogenital disorders
0.000 0.517 0.482
E34.5 Androgen resistance syndrome
0.000 0.521 0.479
E34.4 Constitutional tall stature
0.000 0.521 0.479
E34.3 Short stature, not elsewhere classified
0.000 0.521 0.479
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.521 0.479
E34.1 Other hypersecretion of intestinal hormones
0.000 0.521 0.479
E67 Other hyperalimentation
0.000 0.526 0.474
E68 Sequelae of hyperalimentation
0.000 0.526 0.474
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.527 0.473
E11.8 With unspecified complications
0.000 0.530 0.470
E88.3 Tumour lysis syndrome
0.000 0.532 0.468
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.535 0.465
E45 Retarded development following protein-energy malnutrition
0.000 0.535 0.465
E43 Unspecified severe protein-energy malnutrition
0.000 0.535 0.465
E42 Marasmic kwashiorkor
0.000 0.535 0.465
E41 Nutritional marasmus
0.000 0.535 0.465
E40 Kwashiorkor
0.000 0.535 0.465
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.535 0.465
L10-L14 Bullous disorders
0.000 0.536 0.464
E88.8 Other specified metabolic disorders
0.000 0.536 0.463
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.537 0.463
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.538 0.462
E89.5 Postprocedural testicular hypofunction
0.000 0.538 0.462
E89.4 Postprocedural ovarian failure
0.000 0.538 0.462
L56.9 Acute skin change due to ultraviolet radiation, unspecified
0.000 0.539 0.461
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.541 0.459
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.542 0.458
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.542 0.458
E11.6 With other specified complications
0.000 0.542 0.458
E21.0 Primary hyperparathyroidism
0.000 0.551 0.449
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.561 0.439
E07 Other disorders of thyroid
0.000 0.561 0.439
E20.1 Pseudohypoparathyroidism
0.000 0.562 0.438
E20.0 Idiopathic hypoparathyroidism
0.000 0.562 0.438
L41.9 Parapsoriasis, unspecified
0.000 0.568 0.432
L41.8 Other parapsoriasis
0.000 0.568 0.432
L41.5 Retiform parapsoriasis
0.000 0.568 0.432
L41.4 Large plaque parapsoriasis
0.000 0.568 0.432
L41.3 Small plaque parapsoriasis
0.000 0.568 0.432
L41.2 Lymphomatoid papulosis
0.000 0.568 0.432
L41.1 Pityriasis lichenoides chronica
0.000 0.568 0.432
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.568 0.432
L44.9 Papulosquamous disorder, unspecified
0.000 0.568 0.432
L44.8 Other specified papulosquamous disorders
0.000 0.568 0.432
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.568 0.432
L44.3 Lichen ruber moniliformis
0.000 0.568 0.432
L44.2 Lichen striatus
0.000 0.568 0.432
L44.1 Lichen nitidus
0.000 0.568 0.432
L44.0 Pityriasis rubra pilaris
0.000 0.568 0.432
E89.1 Postprocedural hypoinsulinaemia
0.000 0.569 0.430
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.570 0.430
E88.2 Lipomatosis, not elsewhere classified
0.000 0.571 0.429
E34.9 Endocrine disorder, unspecified
0.000 0.572 0.428
L57.4 Cutis laxa senilis
0.000 0.574 0.426
L56.8 Other specified acute skin changes due to ultraviolet radiation
0.000 0.574 0.426
E78.4 Other hyperlipidaemia
0.000 0.578 0.421
E06.1 Subacute thyroiditis
0.000 0.579 0.421
E89.2 Postprocedural hypoparathyroidism
0.000 0.581 0.419
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.583 0.417
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.585 0.415
E72 Other disorders of amino-acid metabolism
0.000 0.586 0.414
E78.3 Hyperchylomicronaemia
0.000 0.587 0.413
E20.9 Hypoparathyroidism, unspecified
0.000 0.591 0.409
L56.3 Solar urticaria
0.000 0.592 0.408
L56.2 Photocontact dermatitis [berloque dermatitis]
0.000 0.592 0.408
L56.1 Drug photoallergic response
0.000 0.592 0.408
L56.0 Drug phototoxic response
0.000 0.592 0.408
C44.9 Malignant neoplasm of skin, unspecified
0.001 0.595 0.405
E74 Other disorders of carbohydrate metabolism
0.000 0.596 0.404
E73 Lactose intolerance
0.000 0.596 0.403
E85 Amyloidosis
0.000 0.597 0.403
E04.8 Other specified non-toxic goitre
0.000 0.602 0.398
E46 Unspecified protein-energy malnutrition
0.000 0.602 0.398
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.607 0.393
E22.8 Other hyperfunction of pituitary gland
0.000 0.607 0.393
E88.9 Metabolic disorder, unspecified
0.000 0.609 0.390
E22.1 Hyperprolactinaemia
0.000 0.610 0.390
E78.8 Other disorders of lipoprotein metabolism
0.000 0.613 0.387
E11.5 With peripheral circulatory complications
0.000 0.617 0.383
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.618 0.382
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.618 0.382
E16.4 Abnormal secretion of gastrin
0.000 0.618 0.382
E16.3 Increased secretion of glucagon
0.000 0.618 0.382
L55.9 Sunburn, unspecified
0.000 0.622 0.378
L55.8 Other sunburn
0.000 0.622 0.378
L55.2 Sunburn of third degree
0.000 0.622 0.378
L55.1 Sunburn of second degree
0.000 0.622 0.378
L55.0 Sunburn of first degree
0.000 0.622 0.378
E80.4 Gilbert's syndrome
0.000 0.622 0.378
E04.2 Non-toxic multinodular goitre
0.000 0.622 0.378
E34.0 Carcinoid syndrome
0.000 0.623 0.377
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.623 0.377
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.623 0.377
E79.1 Lesch-Nyhan syndrome
0.000 0.623 0.377
L59.9 Disorder of skin and subcutaneous tissue related to radiation, unspecified
0.000 0.625 0.375
L59.0 Erythema ab igne [dermatitis ab igne]
0.000 0.625 0.375
E16.2 Hypoglycaemia, unspecified
0.000 0.627 0.373
E20.8 Other hypoparathyroidism
0.000 0.628 0.371
L59.8 Other specified disorders of skin and subcutaneous tissue related to radiation
0.000 0.630 0.370
L56.4 Polymorphous light eruption
0.000 0.631 0.368
E84.9 Cystic fibrosis, unspecified
0.000 0.634 0.366
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.634 0.366
E11.1 With ketoacidosis
0.000 0.634 0.366
E16.1 Other hypoglycaemia
0.000 0.635 0.365
E84.8 Cystic fibrosis with other manifestations
0.000 0.645 0.355
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.645 0.355
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.645 0.355
E80.6 Other disorders of bilirubin metabolism
0.000 0.645 0.355
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.652 0.347
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.652 0.347
E70.3 Albinism
0.000 0.652 0.347
E70.2 Disorders of tyrosine metabolism
0.000 0.652 0.347
E70.1 Other hyperphenylalaninaemias
0.000 0.652 0.347
E70.0 Classical phenylketonuria
0.000 0.652 0.347
E71.3 Disorders of fatty-acid metabolism
0.000 0.652 0.347
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.652 0.347
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.652 0.347
E71.0 Maple-syrup-urine disease
0.000 0.652 0.347
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.652 0.347
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.652 0.347
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.652 0.347
E76.2 Other mucopolysaccharidoses
0.000 0.652 0.347
E76.1 Mucopolysaccharidosis, type II
0.000 0.652 0.347
E76.0 Mucopolysaccharidosis, type I
0.000 0.652 0.347
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.652 0.347
E77.8 Other disorders of glycoprotein metabolism
0.000 0.652 0.347
E77.1 Defects in glycoprotein degradation
0.000 0.652 0.347
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.652 0.347
L58.1 Chronic radiodermatitis
0.000 0.653 0.347
L58.0 Acute radiodermatitis
0.000 0.653 0.347
L12 Pemphigoid
0.000 0.655 0.345
E67.8 Other specified hyperalimentation
0.000 0.660 0.340
E67.3 Hypervitaminosis D
0.000 0.660 0.340
E67.2 Megavitamin-B6 syndrome
0.000 0.660 0.340
E67.1 Hypercarotenaemia
0.000 0.660 0.340
E67.0 Hypervitaminosis A
0.000 0.660 0.340
C44.5 Skin of trunk
0.000 0.661 0.339
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.661 0.339
E80.5 Crigler-Najjar syndrome
0.000 0.661 0.339
E80.3 Defects of catalase and peroxydase
0.000 0.661 0.339
E80.0 Hereditary erythropoietic porphyria
0.000 0.661 0.339
E44.1 Mild protein-energy malnutrition
0.000 0.666 0.334
E44.0 Moderate protein-energy malnutrition
0.000 0.666 0.334
L10 Pemphigus
0.000 0.667 0.332
L14 Bullous disorders in diseases classified elsewhere
0.000 0.667 0.332
E75.6 Lipid storage disorder, unspecified
0.000 0.668 0.332
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.668 0.332
E75.3 Sphingolipidosis, unspecified
0.000 0.668 0.332
E75.1 Other gangliosidosis
0.000 0.668 0.332
E75.0 GM2 gangliosidosis
0.000 0.668 0.332
L11 Other acantholytic disorders
0.000 0.671 0.329
E75.2 Other sphingolipidosis
0.000 0.675 0.325
E83 Disorders of mineral metabolism
0.072 0.678 0.250
E75.5 Other lipid storage disorders
0.000 0.682 0.318
E50-E64 Other nutritional deficiencies
0.000 0.682 0.318
E80.1 Porphyria cutanea tarda
0.000 0.682 0.318
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.683 0.317
E07.1 Dyshormogenetic goitre
0.000 0.685 0.315
E07.0 Hypersecretion of calcitonin
0.000 0.685 0.315
E04.9 Non-toxic goitre, unspecified
0.000 0.687 0.313
L13 Other bullous disorders
0.000 0.695 0.305
E85.4 Organ-limited amyloidosis
0.000 0.695 0.304
L58.9 Radiodermatitis, unspecified
0.000 0.697 0.303
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.703 0.297
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.703 0.297
E72.5 Disorders of glycine metabolism
0.000 0.703 0.297
E72.4 Disorders of ornithine metabolism
0.000 0.703 0.297
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.703 0.297
E72.2 Disorders of urea cycle metabolism
0.000 0.703 0.297
L60-L75 Disorders of skin appendages
0.000 0.704 0.296
E72.0 Disorders of amino-acid transport
0.000 0.708 0.292
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.710 0.290
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.710 0.290
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.710 0.290
E74.2 Disorders of galactose metabolism
0.000 0.710 0.290
E74.1 Disorders of fructose metabolism
0.000 0.710 0.290
E73.8 Other lactose intolerance
0.000 0.710 0.289
E73.1 Secondary lactase deficiency
0.000 0.710 0.289
E73.0 Congenital lactase deficiency
0.000 0.710 0.289
E85.9 Amyloidosis, unspecified
0.000 0.711 0.289
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.711 0.289
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.711 0.289
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.711 0.289
E74.0 Glycogen storage disease
0.000 0.713 0.287
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.714 0.286
M07 Psoriatic and enteropathic arthropathies
0.000 0.714 0.286
E07.8 Other specified disorders of thyroid
0.000 0.718 0.282
E03 Other hypothyroidism
0.000 0.720 0.280
E22.0 Acromegaly and pituitary gigantism
0.000 0.723 0.277
E80.2 Other porphyria
0.000 0.729 0.271
L12.9 Pemphigoid, unspecified
0.000 0.736 0.264
L71 Rosacea
0.000 0.741 0.259
E78.0 Pure hypercholesterolaemia
0.000 0.744 0.256
E51 Thiamine deficiency
0.000 0.752 0.248
L12.8 Other pemphigoid
0.000 0.752 0.248
L12.3 Acquired epidermolysis bullosa
0.000 0.752 0.248
L12.2 Chronic bullous disease of childhood
0.000 0.752 0.248
L12.1 Cicatricial pemphigoid
0.000 0.753 0.247
E85.8 Other amyloidosis
0.000 0.755 0.245
L12.0 Bullous pemphigoid
0.000 0.755 0.245
E11.9 Without complications
0.000 0.761 0.239
E56 Other vitamin deficiencies
0.000 0.761 0.239
L10.9 Pemphigus, unspecified
0.000 0.761 0.238
L10.8 Other pemphigus
0.000 0.761 0.238
L10.5 Drug-induced pemphigus
0.000 0.761 0.238
L10.4 Pemphigus erythematosus
0.000 0.761 0.238
L10.3 Brazilian pemphigus [fogo selvagem]
0.000 0.761 0.238
L10.2 Pemphigus foliaceus
0.000 0.761 0.238
L10.1 Pemphigus vegetans
0.000 0.761 0.238
L10.0 Pemphigus vulgaris
0.000 0.761 0.238
E85.3 Secondary systemic amyloidosis
0.000 0.762 0.238
L11.0 Acquired keratosis follicularis
0.000 0.763 0.237
L11.9 Acantholytic disorder, unspecified
0.000 0.764 0.236
L11.8 Other specified acantholytic disorders
0.000 0.764 0.236
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.001 0.764 0.235
E11.4 With neurological complications
0.000 0.765 0.235
L68 Hypertrichosis
0.000 0.765 0.235
L50-L54 Urticaria and erythema
0.000 0.767 0.233
E83.9 Disorder of mineral metabolism, unspecified
0.052 0.769 0.180
E83.8 Other disorders of mineral metabolism
0.052 0.769 0.180
E83.2 Disorders of zinc metabolism
0.052 0.769 0.180
E83.0 Disorders of copper metabolism
0.052 0.769 0.180
L11.1 Transient acantholytic dermatosis [Grover]
0.000 0.770 0.230
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.772 0.228
E50 Vitamin A deficiency
0.000 0.772 0.228
E60 Dietary zinc deficiency
0.000 0.772 0.228
E59 Dietary selenium deficiency
0.000 0.772 0.228
E52 Niacin deficiency [pellagra]
0.000 0.772 0.228
L71.9 Rosacea, unspecified
0.000 0.775 0.225
L66 Cicatricial alopecia [scarring hair loss]
0.000 0.775 0.225
L13.9 Bullous disorder, unspecified
0.000 0.781 0.218
L13.8 Other specified bullous disorders
0.000 0.781 0.218
L13.1 Subcorneal pustular dermatitis
0.000 0.781 0.218
E63 Other nutritional deficiencies
0.000 0.783 0.217
E83.4 Disorders of magnesium metabolism
0.010 0.784 0.207
L63 Alopecia areata
0.000 0.784 0.216
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.785 0.214
L75 Apocrine sweat disorders
0.000 0.788 0.212
L74 Eccrine sweat disorders
0.000 0.788 0.212
L67 Hair colour and hair shaft abnormalities
0.000 0.788 0.212
L64 Androgenic alopecia
0.000 0.788 0.212
L62 Nail disorders in diseases classified elsewhere
0.000 0.788 0.212
E55 Vitamin D deficiency
0.000 0.788 0.212
L60 Nail disorders
0.000 0.790 0.210
E73.9 Lactose intolerance, unspecified
0.000 0.791 0.208
E54 Ascorbic acid deficiency
0.000 0.794 0.205
M07.5 Arthropathy in ulcerative colitis
0.000 0.795 0.205
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.795 0.205
M07.2 Psoriatic spondylitis
0.000 0.795 0.205
M07.1 Arthritis mutilans
0.000 0.795 0.205
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.795 0.205
L71.1 Rhinophyma
0.000 0.799 0.201
E03.5 Myxoedema coma
0.000 0.799 0.201
E03.4 Atrophy of thyroid (acquired)
0.000 0.799 0.201
E03.3 Postinfectious hypothyroidism
0.000 0.799 0.201
E58 Dietary calcium deficiency
0.000 0.801 0.199
E51.2 Wernicke's encephalopathy
0.000 0.801 0.198
L60.9 Nail disorder, unspecified
0.000 0.802 0.198

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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