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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7383606
log Bayes Factor = 179.21
Chromosome 6   position 32,766,593  (GRCh37) Explore rs7383606 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
H36.0 Diabetic retinopathy
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E10.1 With ketoacidosis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
H30-H36 Disorders of choroid and retina
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
H36 Retinal disorders in diseases classified elsewhere
1.000 0.000 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
1.000 0.000 0.000
E16 Other disorders of pancreatic internal secretion
1.000 0.000 0.000
E16.2 Hypoglycaemia, unspecified
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
# Top node
0.999 0.001 0.000
E20-E35 Disorders of other endocrine glands
0.999 0.001 0.000
H35 Other retinal disorders
0.998 0.002 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.998 0.002 0.000
E10.4 With neurological complications
0.996 0.004 0.000
D50-D53 Nutritional anaemias
0.996 0.004 0.000
E10.2 With renal complications
0.995 0.005 0.000
D80-D89 Certain disorders involving the immune mechanism
0.992 0.008 0.000
E27 Other disorders of adrenal gland
0.986 0.014 0.000
N00-N08 Glomerular diseases
0.985 0.015 0.000
D86 Sarcoidosis
0.982 0.018 0.000
Chapter XIV Diseases of the genitourinary system
0.981 0.019 0.000
E27.1 Primary adrenocortical insufficiency
0.981 0.019 0.000
H35.2 Other proliferative retinopathy
0.978 0.022 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.973 0.027 0.000
D50 Iron deficiency anaemia
0.971 0.029 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.968 0.032 0.000
N04 Nephrotic syndrome
0.967 0.033 0.000
H35.8 Other specified retinal disorders
0.965 0.035 0.000
H10-H13 Disorders of conjunctiva
0.962 0.038 0.000
D60-D64 Aplastic and other anaemias
0.961 0.039 0.000
E10.5 With peripheral circulatory complications
0.960 0.040 0.000
N25-N29 Other disorders of kidney and ureter
0.959 0.041 0.000
N17-N19 Renal failure
0.959 0.041 0.000
E11 Non-insulin-dependent diabetes mellitus
0.958 0.042 0.000
Q50-Q56 Congenital malformations of genital organs
0.955 0.045 0.000
E11.3 With ophthalmic complications
0.953 0.047 0.000
N18 Chronic renal failure
0.951 0.049 0.000
E70-E90 Metabolic disorders
0.951 0.049 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.950 0.050 0.000
E89.0 Postprocedural hypothyroidism
0.949 0.051 0.000
D50.9 Iron deficiency anaemia, unspecified
0.948 0.052 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.937 0.063 0.000
N04.9 Unspecified
0.937 0.063 0.000
D51 Vitamin B12 deficiency anaemia
0.936 0.064 0.000
E24 Cushing's syndrome
0.935 0.065 0.000
N05 Unspecified nephritic syndrome
0.934 0.066 0.000
H35.4 Peripheral retinal degeneration
0.932 0.068 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.929 0.071 0.000
E10.0 With coma
0.924 0.076 0.000
D61 Other aplastic anaemias
0.924 0.076 0.000
E22 Hyperfunction of pituitary gland
0.917 0.083 0.000
D86.9 Sarcoidosis, unspecified
0.917 0.083 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.917 0.083 0.000
N18.0 End-stage renal disease
0.913 0.087 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.911 0.089 0.000
E85 Amyloidosis
0.905 0.095 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.904 0.096 0.000
D61.9 Aplastic anaemia, unspecified
0.897 0.103 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.896 0.104 0.000
Q00-Q07 Congenital malformations of the nervous system
0.893 0.107 0.000
D86.0 Sarcoidosis of lung
0.884 0.116 0.000
H10 Conjunctivitis
0.876 0.124 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.873 0.127 0.000
E40-E46 Malnutrition
0.873 0.127 0.000
H11 Other disorders of conjunctiva
0.870 0.130 0.000
H53-H54 Visual disturbances and blindness
0.867 0.133 0.000
N18.2 Chronic kidney disease, stage 2
0.865 0.135 0.000
N28.0 Ischaemia and infarction of kidney
0.860 0.140 0.000
E10.8 With unspecified complications
0.860 0.140 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.855 0.145 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.855 0.145 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.852 0.148 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.851 0.149 0.000
N05.1 Focal and segmental glomerular lesions
0.848 0.152 0.000
D89.2 Hypergammaglobulinaemia, unspecified
0.846 0.154 0.000
E14 Unspecified diabetes mellitus
0.844 0.156 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.844 0.156 0.000
N18.5 Chronic kidney disease, stage 5
0.841 0.159 0.000
H11.0 Pterygium
0.840 0.160 0.000
Q80-Q89 Other congenital malformations
0.840 0.160 0.000
D53 Other nutritional anaemias
0.840 0.160 0.000
H06.2 Dysthyroid exophthalmos
0.840 0.160 0.000
N08.5 Glomerular disorders in systemic connective tissue disorders
0.838 0.162 0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.838 0.162 0.000
Q55 Other congenital malformations of male genital organs
0.837 0.163 0.000
E10.6 With other specified complications
0.837 0.163 0.000
H53 Visual disturbances
0.836 0.164 0.000
E10.7 With multiple complications
0.835 0.165 0.000
N03 Chronic nephritic syndrome
0.830 0.170 0.000
Q44.6 Cystic disease of liver
0.827 0.173 0.000
N18.4 Chronic kidney disease, stage 4
0.826 0.174 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.825 0.175 0.000
H30 Chorioretinal inflammation
0.820 0.180 0.000
H35.0 Background retinopathy and retinal vascular changes
0.820 0.180 0.000
D86.3 Sarcoidosis of skin
0.819 0.181 0.000
Q43 Other congenital malformations of intestine
0.817 0.183 0.000
H35.6 Retinal haemorrhage
0.817 0.183 0.000
E24.2 Drug-induced Cushing's syndrome
0.814 0.186 0.000
E85.9 Amyloidosis, unspecified
0.814 0.186 0.000
D50.8 Other iron deficiency anaemias
0.811 0.189 0.000
E28 Ovarian dysfunction
0.810 0.190 0.000
E23 Hypofunction and other disorders of pituitary gland
0.809 0.191 0.000
N18.9 Chronic renal failure, unspecified
0.806 0.194 0.000
N05.2 Diffuse membranous glomerulonephritis
0.805 0.195 0.000
H53.1 Subjective visual disturbances
0.802 0.198 0.000
Q50.4 Embryonic cyst of Fallopian tube
0.797 0.203 0.000
E14.3 With ophthalmic complications
0.794 0.206 0.000
N25 Disorders resulting from impaired renal tubular function
0.792 0.208 0.000
E11.7 With multiple complications
0.792 0.208 0.000
H10.9 Conjunctivitis, unspecified
0.791 0.209 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.791 0.209 0.000
N04.1 Focal and segmental glomerular lesions
0.790 0.210 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.790 0.210 0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.789 0.211 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.787 0.213 0.000
N04.2 Diffuse membranous glomerulonephritis
0.787 0.213 0.000
E24.8 Other Cushing's syndrome
0.785 0.215 0.000
D86.8 Sarcoidosis of other and combined sites
0.784 0.216 0.000
E46 Unspecified protein-energy malnutrition
0.781 0.219 0.000
N27 Small kidney of unknown cause
0.776 0.224 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.776 0.224 0.000
E65-E68 Obesity and other hyperalimentation
0.775 0.225 0.000
D50.1 Sideropenic dysphagia
0.773 0.227 0.000
D52 Folate deficiency anaemia
0.771 0.229 0.000
E89.4 Postprocedural ovarian failure
0.771 0.229 0.000
H53.4 Visual field defects
0.769 0.231 0.000
E85.4 Organ-limited amyloidosis
0.765 0.235 0.000
N17 Acute renal failure
0.762 0.238 0.000
Q85 Phakomatoses, not elsewhere classified
0.760 0.240 0.000
D55-D59 Haemolytic anaemias
0.757 0.243 0.000
Q44.5 Other congenital malformations of bile ducts
0.756 0.244 0.000
D89.1 Cryoglobulinaemia
0.756 0.244 0.000
D64 Other anaemias
0.754 0.246 0.000
Chapter I Certain infectious and parasitic diseases
0.754 0.246 0.000
Q05 Spina bifida
0.753 0.247 0.000
E11.1 With ketoacidosis
0.750 0.250 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.748 0.252 0.000
Q52 Other congenital malformations of female genitalia
0.746 0.254 0.000
D86.1 Sarcoidosis of lymph nodes
0.745 0.255 0.000
Q35-Q37 Cleft lip and cleft palate
0.745 0.255 0.000
Q44.4 Choledochal cyst
0.744 0.256 0.000
E31 Polyglandular dysfunction
0.744 0.256 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.743 0.257 0.000
E23.7 Disorder of pituitary gland, unspecified
0.743 0.257 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.742 0.258 0.000
E16.1 Other hypoglycaemia
0.740 0.260 0.000
Q53 Undescended testicle
0.738 0.262 0.000
E24.0 Pituitary-dependent Cushing's disease
0.737 0.263 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.735 0.265 0.000
N00 Acute nephritic syndrome
0.735 0.265 0.000
E70 Disorders of aromatic amino-acid metabolism
0.734 0.266 0.000
Q51 Congenital malformations of uterus and cervix
0.733 0.267 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.733 0.267 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.732 0.268 0.000
E11.2 With renal complications
0.730 0.270 0.000
E85.3 Secondary systemic amyloidosis
0.728 0.272 0.000
D53.9 Nutritional anaemia, unspecified
0.728 0.272 0.000
E84 Cystic fibrosis
0.724 0.276 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.724 0.276 0.000
E79 Disorders of purine and pyrimidine metabolism
0.722 0.278 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.722 0.278 0.000
D51.8 Other vitamin B12 deficiency anaemias
0.721 0.279 0.000
E03.1 Congenital hypothyroidism without goitre
0.721 0.279 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.719 0.281 0.000
E22.1 Hyperprolactinaemia
0.718 0.282 0.000
N05.9 Unspecified
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.717 0.283 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.717 0.283 0.000
E15 Nondiabetic hypoglycaemic coma
0.717 0.283 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.717 0.283 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.717 0.283 0.000
E16.4 Abnormal secretion of gastrin
0.717 0.283 0.000
E16.3 Increased secretion of glucagon
0.717 0.283 0.000
H11.9 Disorder of conjunctiva, unspecified
0.717 0.283 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.716 0.284 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.716 0.284 0.000
E32 Diseases of thymus
0.716 0.284 0.000
E30 Disorders of puberty, not elsewhere classified
0.716 0.284 0.000
E25 Adrenogenital disorders
0.716 0.284 0.000
D63.0 Anaemia in neoplastic disease
0.716 0.284 0.000
H35.1 Retinopathy of prematurity
0.716 0.284 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.716 0.284 0.000
E07 Other disorders of thyroid
0.716 0.284 0.000
B25-B34 Other viral diseases
0.714 0.286 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.713 0.287 0.000
D89.9 Disorder involving the immune mechanism, unspecified
0.713 0.287 0.000
D61.1 Drug-induced aplastic anaemia
0.712 0.287 0.000
D81 Combined immunodeficiencies
0.711 0.289 0.000
Q43.9 Congenital malformation of intestine, unspecified
0.711 0.289 0.000
N26 Unspecified contracted kidney
0.711 0.289 0.000
H10.1 Acute atopic conjunctivitis
0.711 0.289 0.000
E27.5 Adrenomedullary hyperfunction
0.707 0.293 0.000
E27.0 Other adrenocortical overactivity
0.707 0.293 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.706 0.294 0.000
N06 Isolated proteinuria with specified morphological lesion
0.706 0.294 0.000
N01 Rapidly progressive nephritic syndrome
0.706 0.294 0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.706 0.294 0.000
H13 Disorders of conjunctiva in diseases classified elsewhere
0.705 0.295 0.000
H01 Other inflammation of eyelid
0.703 0.297 0.000
Q06 Other congenital malformations of spinal cord
0.701 0.299 0.000
B25 Cytomegaloviral disease
0.700 0.300 0.000
Q60-Q64 Congenital malformations of the urinary system
0.699 0.301 0.000
E24.9 Cushing's syndrome, unspecified
0.698 0.302 0.000
Q55.6 Other congenital malformations of penis
0.698 0.302 0.000
N08.8 Glomerular disorders in other diseases classified elsewhere
0.697 0.302 0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.697 0.302 0.000
N08.1 Glomerular disorders in neoplastic diseases
0.697 0.302 0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.697 0.302 0.000
H15 Disorders of sclera
0.697 0.303 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.697 0.303 0.000
Q45 Other congenital malformations of digestive system
0.696 0.304 0.000
E03.8 Other specified hypothyroidism
0.695 0.305 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.694 0.306 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.694 0.306 0.000
Q55.2 Other congenital malformations of testis and scrotum
0.694 0.306 0.000
H05 Disorders of orbit
0.694 0.306 0.000
N04.8 Other
0.693 0.307 0.000
N04.7 Diffuse crescentic glomerulonephritis
0.693 0.307 0.000
N04.6 Dense deposit disease
0.693 0.307 0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis
0.693 0.307 0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis
0.693 0.307 0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis
0.693 0.307 0.000
N04.0 Minor glomerular abnormality
0.693 0.307 0.000
E23.6 Other disorders of pituitary gland
0.693 0.307 0.000
E14.8 With unspecified complications
0.693 0.307 0.000
H30.9 Chorioretinal inflammation, unspecified
0.691 0.309 0.000
Q07 Other congenital malformations of nervous system
0.689 0.311 0.000
N03.8 Other
0.689 0.311 0.000
E20 Hypoparathyroidism
0.688 0.312 0.000
B25.9 Cytomegaloviral disease, unspecified
0.687 0.313 0.000
B15-B19 Viral hepatitis
0.687 0.313 0.000
A63.0 Anogenital (venereal) warts
0.687 0.313 0.000
E27.9 Disorder of adrenal gland, unspecified
0.686 0.314 0.000
Q56 Indeterminate sex and pseudohermaphroditism
0.685 0.315 0.000
Z83.7 Family history of diseases of the digestive system
0.684 0.316 0.000
E28.3 Primary ovarian failure
0.684 0.316 0.000
Q40 Other congenital malformations of upper alimentary tract
0.683 0.317 0.000
E77 Disorders of glycoprotein metabolism
0.682 0.318 0.000
E76 Disorders of glycosaminoglycan metabolism
0.682 0.318 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.682 0.318 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.682 0.318 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.682 0.318 0.000
D51.3 Other dietary vitamin B12 deficiency anaemia
0.682 0.318 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.681 0.319 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.681 0.319 0.000
E89.5 Postprocedural testicular hypofunction
0.681 0.319 0.000
E89.1 Postprocedural hypoinsulinaemia
0.681 0.319 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.681 0.319 0.000
Q39 Congenital malformations of oesophagus
0.681 0.319 0.000
Q50.5 Embryonic cyst of broad ligament
0.681 0.319 0.000
E34 Other endocrine disorders
0.680 0.320 0.000
E29 Testicular dysfunction
0.679 0.321 0.000
E72 Other disorders of amino-acid metabolism
0.678 0.321 0.000
E14.2 Withrenal complications
0.678 0.322 0.000
D82 Immunodeficiency associated with other major defects
0.676 0.323 0.000
Q85.9 Phakomatosis, unspecified
0.676 0.324 0.000
D83 Common variable immunodeficiency
0.674 0.326 0.000
D51.2 Transcobalamin II deficiency
0.671 0.329 0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.671 0.329 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.670 0.330 0.000
E24.3 Ectopic ACTH syndrome
0.670 0.330 0.000
E24.1 Nelson's syndrome
0.670 0.330 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.670 0.330 0.000
N05.6 Dense deposit disease
0.670 0.330 0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis
0.670 0.330 0.000
N05.0 Minor glomerular abnormality
0.670 0.330 0.000
Z83 Family history of other specific disorders
0.666 0.334 0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.666 0.334 0.000
D89.3 Immune reconstitution syndrome
0.666 0.334 0.000
E11.0 With coma
0.666 0.334 0.000
H16 Keratitis
0.664 0.336 0.000
D61.8 Other specified aplastic anaemias
0.662 0.338 0.000
D61.3 Idiopathic aplastic anaemia
0.662 0.338 0.000
D61.2 Aplastic anaemia due to other external agents
0.662 0.338 0.000
Q03 Congenital hydrocephalus
0.661 0.339 0.000
N05.7 Diffuse crescentic glomerulonephritis
0.661 0.339 0.000
A80-A89 Viral infections of the central nervous system
0.660 0.340 0.000
D89.0 Polyclonal hypergammaglobulinaemia
0.658 0.342 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.657 0.342 0.000
E22.8 Other hyperfunction of pituitary gland
0.657 0.342 0.000
Q44.7 Other congenital malformations of liver
0.657 0.343 0.000
Q44.3 Congenital stenosis and stricture of bile ducts
0.657 0.343 0.000
Q44.2 Atresia of bile ducts
0.657 0.343 0.000
Q44.1 Other congenital malformations of gallbladder
0.657 0.343 0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder
0.657 0.343 0.000
E85.8 Other amyloidosis
0.655 0.345 0.000
Q05.9 Spina bifida, unspecified
0.654 0.346 0.000
N18.1 Chronic kidney disease, stage 1
0.654 0.346 0.000
Q82 Other congenital malformations of skin
0.654 0.346 0.000
H15.8 Other disorders of sclera
0.654 0.346 0.000
E27.8 Other specified disorders of adrenal gland
0.653 0.347 0.000
D59 Acquired haemolytic anaemia
0.651 0.349 0.000
Q43.3 Congenital malformations of intestinal fixation
0.650 0.350 0.000
Q04 Other congenital malformations of brain
0.649 0.351 0.000
E85.2 Heredofamilial amyloidosis, unspecified
0.649 0.351 0.000
E85.1 Neuropathic heredofamilial amyloidosis
0.649 0.351 0.000
E85.0 Nonneuropathic heredofamilial amyloidosis
0.649 0.351 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.645 0.355 0.000
H01.8 Other specified inflammation of eyelid
0.642 0.358 0.000
Q01 Encephalocele
0.640 0.360 0.000
Q00 Anencephaly and similar malformations
0.640 0.360 0.000
Q02 Microcephaly
0.640 0.360 0.000
E11.6 With other specified complications
0.639 0.361 0.000
N03.5 Diffuse mesangiocapillary glomerulonephritis
0.637 0.363 0.000
H53.3 Other disorders of binocular vision
0.636 0.364 0.000
D80 Immunodeficiency with predominantly antibody defects
0.635 0.365 0.000
Q51.2 Other doubling of uterus
0.634 0.366 0.000
Z83.5 Family history of eye and ear disorders
0.634 0.366 0.000
Q24 Other congenital malformations of heart
0.634 0.366 0.000
E73 Lactose intolerance
0.634 0.366 0.000
N25.0 Renal osteodystrophy
0.633 0.366 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.630 0.370 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.630 0.370 0.000
Q27 Other congenital malformations of peripheral vascular system
0.630 0.370 0.000
E13 Other specified diabetes mellitus
0.629 0.371 0.000
E11.5 With peripheral circulatory complications
0.629 0.371 0.000
H10.8 Other conjunctivitis
0.628 0.372 0.000
H10.5 Blepharoconjunctivitis
0.628 0.372 0.000
H10.3 Acute conjunctivitis, unspecified
0.628 0.372 0.000
H10.2 Other acute conjunctivitis
0.628 0.372 0.000
H10.0 Mucopurulent conjunctivitis
0.628 0.372 0.000
H11.1 Conjunctival degenerations and deposits
0.628 0.372 0.000
H53.0 Amblyopia ex anopsia
0.628 0.372 0.000
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament
0.626 0.374 0.000
Q50.3 Other congenital malformations of ovary
0.626 0.374 0.000
Q50.2 Congenital torsion of ovary
0.626 0.374 0.000
Q50.1 Developmental ovarian cyst
0.626 0.374 0.000
Q50.0 Congenital absence of ovary
0.626 0.374 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.626 0.374 0.000
E45 Retarded development following protein-energy malnutrition
0.626 0.374 0.000
E43 Unspecified severe protein-energy malnutrition
0.626 0.374 0.000
E42 Marasmic kwashiorkor
0.626 0.374 0.000
E41 Nutritional marasmus
0.626 0.374 0.000
E40 Kwashiorkor
0.626 0.374 0.000
D64.8 Other specified anaemias
0.623 0.377 0.000
H53.9 Visual disturbance, unspecified
0.622 0.378 0.000
N03.1 Focal and segmental glomerular lesions
0.621 0.379 0.000
N25.8 Other disorders resulting from impaired renal tubular function
0.620 0.380 0.000
Z83.3 Family history of diabetes mellitus
0.618 0.382 0.000
Q28 Other congenital malformations of circulatory system
0.618 0.382 0.000
Q38.7 Pharyngeal pouch
0.615 0.385 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.615 0.385 0.000
N27.1 Small kidney, bilateral
0.612 0.388 0.000
Q38.5 Congenital malformations of palate, not elsewhere classified
0.611 0.389 0.000
H10.4 Chronic conjunctivitis
0.610 0.389 0.000
D52.9 Folate deficiency anaemia, unspecified
0.610 0.390 0.000
N17.0 Acute renal failure with tubular necrosis
0.607 0.393 0.000
E14.7 With multiple complications
0.605 0.394 0.000
E14.0 With coma
0.605 0.394 0.000
H06.3 Other disorders of orbit in diseases classified elsewhere
0.605 0.395 0.000
H06.1 Parasitic infestation of orbit in diseases classified elsewhere
0.605 0.395 0.000
H06.0 Disorders of lachrymal system in diseases classified elsewhere
0.605 0.395 0.000
E05.8 Other thyrotoxicosis
0.604 0.396 0.000
E89.2 Postprocedural hypoparathyroidism
0.603 0.397 0.000
Q43.1 Hirschsprung's disease
0.602 0.398 0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified
0.602 0.398 0.000
Q84 Other congenital malformations of integument
0.602 0.398 0.000
Q81 Epidermolysis bullosa
0.602 0.398 0.000
Q80 Congenital ichthyosis
0.602 0.398 0.000
D53.8 Other specified nutritional anaemias
0.602 0.398 0.000
D53.2 Scorbutic anaemia
0.602 0.398 0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.602 0.398 0.000
D53.0 Protein deficiency anaemia
0.602 0.398 0.000
Q61 Cystic kidney disease
0.602 0.398 0.000
N27.0 Small kidney, unilateral
0.601 0.399 0.000
D61.0 Constitutional aplastic anaemia
0.601 0.399 0.000
E66 Obesity
0.601 0.399 0.000
Q55.9 Congenital malformation of male genital organ, unspecified
0.600 0.400 0.000
Q55.8 Other specified congenital malformations of male genital organs
0.600 0.400 0.000
Q55.5 Congenital absence and aplasia of penis
0.600 0.400 0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate
0.600 0.400 0.000
Q55.3 Atresia of vas deferens
0.600 0.400 0.000
Q55.1 Hypoplasia of testis and scrotum
0.600 0.400 0.000
Q55.0 Absence and aplasia of testis
0.600 0.400 0.000
E14.1 With ketoacidosis
0.600 0.400 0.000
H53.6 Night blindness
0.599 0.401 0.000
H53.5 Colour vision deficiencies
0.599 0.401 0.000
E22.0 Acromegaly and pituitary gigantism
0.598 0.402 0.000
H01.9 Inflammation of eyelid, unspecified
0.598 0.402 0.000
Q22.1 Congenital pulmonary valve stenosis
0.598 0.402 0.000
Q82.8 Other specified congenital malformations of skin
0.597 0.403 0.000
N03.7 Diffuse crescentic glomerulonephritis
0.595 0.405 0.000
N03.6 Dense deposit disease
0.595 0.405 0.000
N03.4 Diffuse endocapillary proliferative glomerulonephritis
0.595 0.405 0.000
N03.3 Diffuse mesangial proliferative glomerulonephritis
0.595 0.405 0.000
N03.2 Diffuse membranous glomerulonephritis
0.595 0.405 0.000
N03.0 Minor glomerular abnormality
0.595 0.405 0.000
B18 Chronic viral hepatitis
0.595 0.405 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.594 0.406 0.000
Q52.4 Other congenital malformations of vagina
0.593 0.407 0.000
A15-A19 Tuberculosis
0.593 0.407 0.000
D63.1 Anaemia in other chronic diseases classified elsewhere
0.591 0.408 0.000
D84 Other immunodeficiencies
0.591 0.409 0.000
N25.9 Disorder resulting from impaired renal tubular function, unspecified
0.591 0.409 0.000
Q85.0 Neurofibromatosis (nonmalignant)
0.588 0.411 0.000
Q43.8 Other specified congenital malformations of intestine
0.588 0.412 0.000
H30.8 Other chorioretinal inflammations
0.588 0.412 0.000
H30.2 Posterior cyclitis
0.588 0.412 0.000
H30.1 Disseminated chorioretinal inflammation
0.588 0.412 0.000
H30.0 Focal chorioretinal inflammation
0.588 0.412 0.000
H53.2 Diplopia
0.588 0.412 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.587 0.413 0.000
H05.2 Exophthalmic conditions
0.587 0.413 0.000
E89.3 Postprocedural hypopituitarism
0.587 0.413 0.000
Q43.7 Persistent cloaca
0.586 0.414 0.000
Q43.6 Congenital fistula of rectum and anus
0.586 0.414 0.000
Q43.5 Ectopic anus
0.586 0.414 0.000
Q43.4 Duplication of intestine
0.586 0.414 0.000
Q43.2 Other congenital functional disorders of colon
0.586 0.414 0.000
H35.9 Retinal disorder, unspecified
0.585 0.415 0.000
Q51.8 Other congenital malformations of uterus and cervix
0.584 0.416 0.000
H31 Other disorders of choroid
0.583 0.417 0.000
Q53.1 Undescended testicle, unilateral
0.583 0.417 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.581 0.419 0.000
E28.9 Ovarian dysfunction, unspecified
0.581 0.419 0.000
E28.8 Other ovarian dysfunction
0.581 0.419 0.000
E28.1 Androgen excess
0.581 0.419 0.000
E28.0 Oestrogen excess
0.581 0.419 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.580 0.420 0.000
E23.1 Drug-induced hypopituitarism
0.580 0.420 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.579 0.420 0.000
H35.5 Hereditary retinal dystrophy
0.579 0.421 0.000
E70.3 Albinism
0.578 0.421 0.000
N03.9 Unspecified
0.578 0.422 0.000
N05.8 Other
0.577 0.423 0.000
H33 Retinal detachments and breaks
0.577 0.423 0.000
Q85.8 Other phakomatoses, not elsewhere classified
0.576 0.424 0.000
E21.2 Other hyperparathyroidism
0.575 0.425 0.000
E06 Thyroiditis
0.574 0.426 0.000
D59.1 Other autoimmune haemolytic anaemias
0.574 0.426 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.574 0.426 0.000
D60.9 Acquired pure red cell aplasia, unspecified
0.573 0.427 0.000
E66.8 Other obesity
0.573 0.427 0.000
E14.5 With peripheral circulatory complications
0.572 0.428 0.000
E65 Localised adiposity
0.572 0.428 0.000
H05.0 Acute inflammation of orbit
0.571 0.429 0.000
B17 Other acute viral hepatitis
0.571 0.429 0.000
E50-E64 Other nutritional deficiencies
0.569 0.431 0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis
0.569 0.431 0.000
Q26 Congenital malformations of great veins
0.567 0.433 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.567 0.433 0.000
A63.8 Other specified predominantly sexually transmitted diseases
0.566 0.434 0.000
Q06.8 Other specified congenital malformations of spinal cord
0.563 0.437 0.000
E28.2 Polycystic ovarian syndrome
0.563 0.437 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.562 0.438 0.000
E84.9 Cystic fibrosis, unspecified
0.562 0.438 0.000
N18.8 Other chronic renal failure
0.562 0.438 0.000
E31.0 Autoimmune polyglandular failure
0.561 0.438 0.000
N17.8 Other acute renal failure
0.561 0.439 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.561 0.439 0.000
E14.6 With other specified complications
0.560 0.440 0.000
E21.4 Other specified disorders of parathyroid gland
0.560 0.440 0.000
A65-A69 Other spirochaetal diseases
0.560 0.440 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.560 0.440 0.000
H11.4 Other conjunctival vascular disorders and cysts
0.559 0.441 0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.558 0.442 0.000
P10-P15 Birth trauma
0.558 0.442 0.000
N27.9 Small kidney, unspecified
0.556 0.443 0.000
Q38.8 Other congenital malformations of pharynx
0.556 0.444 0.000
Q38.4 Congenital malformations of salivary glands and ducts
0.556 0.444 0.000
Q38.3 Other congenital malformations of tongue
0.556 0.444 0.000
Q38.2 Macroglossia
0.556 0.444 0.000
Q38.1 Ankyloglossia
0.556 0.444 0.000
Q38.0 Congenital malformations of lips, not elsewhere classified
0.556 0.444 0.000
N00.9 Unspecified
0.556 0.444 0.000
E67 Other hyperalimentation
0.556 0.444 0.000
E68 Sequelae of hyperalimentation
0.556 0.444 0.000
E07.8 Other specified disorders of thyroid
0.554 0.446 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.554 0.446 0.000
B25.8 Other cytomegaloviral diseases
0.554 0.446 0.000
Q45.9 Congenital malformation of digestive system, unspecified
0.554 0.446 0.000
D52.8 Other folate deficiency anaemias
0.553 0.447 0.000
D52.1 Drug-induced folate deficiency anaemia
0.553 0.447 0.000
D52.0 Dietary folate deficiency anaemia
0.553 0.447 0.000
Q37 Cleft palate with cleft lip
0.552 0.448 0.000
Q52.1 Doubling of vagina
0.551 0.448 0.000
N29.8 Other disorders of kidney and ureter in other diseases classified elsewhere
0.551 0.449 0.000
N17.9 Acute renal failure, unspecified
0.550 0.450 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.550 0.450 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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