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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7403531
log Bayes Factor = 8.61662
Chromosome 15   position 38,822,905  (GRCh37) Explore rs7403531 on Ensembl!
Variant rs7403531 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E03 Other hypothyroidism
0.971 0.029 0.000
E00-E07 Disorders of thyroid gland
0.951 0.049 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.941 0.059 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.913 0.087 0.000
E05.9 Thyrotoxicosis, unspecified
0.908 0.092 0.000
M40-M43 Deforming dorsopathies
0.905 0.095 0.000
M43 Other deforming dorsopathies
0.903 0.097 0.000
M43.1 Spondylolisthesis
0.897 0.103 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.896 0.104 0.000
M20-M25 Other joint disorders
0.895 0.105 0.000
M43.17 Spondylolisthesis (Lumbosacral region)
0.890 0.110 0.000
M86-M90 Other osteopathies
0.882 0.118 0.000
E50-E64 Other nutritional deficiencies
0.880 0.120 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.877 0.123 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.868 0.132 0.000
E53 Deficiency of other B group vitamins
0.868 0.132 0.000
E53.8 Deficiency of other specified B group vitamins
0.861 0.139 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.848 0.152 0.000
M60-M63 Disorders of muscles
0.846 0.154 0.000
M31 Other necrotising vasculopathies
0.833 0.167 0.000
M80-M85 Disorders of bone density and structure
0.831 0.169 0.000
M89 Other disorders of bone
0.830 0.170 0.000
M22 Disorders of patella
0.826 0.174 0.000
M21 Other acquired deformities of limbs
0.813 0.187 0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified
0.804 0.196 0.000
M62 Other disorders of muscle
0.804 0.196 0.000
M87 Osteonecrosis
0.795 0.205 0.000
M89.8 Other specified disorders of bone
0.794 0.206 0.000
M43.0 Spondylolysis
0.789 0.211 0.000
D86 Sarcoidosis
0.789 0.211 0.000
D86.9 Sarcoidosis, unspecified
0.772 0.228 0.000
M62.8 Other specified disorders of muscle
0.765 0.235 0.000
M25 Other joint disorders, not elsewhere classified
0.763 0.237 0.000
M84 Disorders of continuity of bone
0.758 0.242 0.000
M31.3 Wegener's granulomatosis
0.757 0.243 0.000
D86.0 Sarcoidosis of lung
0.756 0.244 0.000
M30 Polyarteritis nodosa and related conditions
0.749 0.251 0.000
E61 Deficiency of other nutrient elements
0.748 0.252 0.000
E03.1 Congenital hypothyroidism without goitre
0.744 0.256 0.000
D86.1 Sarcoidosis of lymph nodes
0.740 0.260 0.000
E03.8 Other specified hypothyroidism
0.739 0.261 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.737 0.263 0.000
M25.7 Osteophyte
0.735 0.265 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.731 0.269 0.000
E05.8 Other thyrotoxicosis
0.731 0.269 0.000
M22.2 Patellofemoral disorders
0.730 0.270 0.000
M43.19 Spondylolisthesis (Site unspecified)
0.727 0.273 0.000
D86.8 Sarcoidosis of other and combined sites
0.727 0.273 0.000
M25.71 Osteophyte (Shoulder region)
0.726 0.274 0.000
M31.1 Thrombotic microangiopathy
0.725 0.275 0.000
M43.02 Spondylolysis (Cervical region)
0.722 0.278 0.000
M21.1 Varus deformity, not elsewhere classified
0.722 0.278 0.000
M35 Other systemic involvement of connective tissue
0.719 0.281 0.000
D80-D89 Certain disorders involving the immune mechanism
0.716 0.284 0.000
# Top node
0.707 0.293 0.000
E20-E35 Disorders of other endocrine glands
0.705 0.295 0.000
M22.8 Other disorders of patella
0.703 0.297 0.000
M05-M14 Inflammatory polyarthropathies
0.702 0.298 0.000
M43.8 Other specified deforming dorsopathies
0.698 0.302 0.000
M00-M03 Infectious arthropathies
0.697 0.303 0.000
E03.5 Myxoedema coma
0.696 0.304 0.000
E03.4 Atrophy of thyroid (acquired)
0.696 0.304 0.000
E03.3 Postinfectious hypothyroidism
0.696 0.304 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.696 0.304 0.000
Chapter XX External causes of morbidity and mortality
0.695 0.305 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.694 0.306 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.692 0.308 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.681 0.318 0.000
E00 Congenital iodine-deficiency syndrome
0.681 0.318 0.000
M87.9 Osteonecrosis, unspecified
0.681 0.319 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.680 0.320 0.000
M62.89 Other specified disorders of muscle (Site unspecified)
0.680 0.320 0.000
M31.7 Microscopic polyangiitis
0.679 0.321 0.000
M65-M68 Disorders of synovium and tendon
0.679 0.321 0.000
M21.6 Other acquired deformities of ankle and foot
0.679 0.321 0.000
M62.80 Other specified disorders of muscle (Multiple sites)
0.678 0.322 0.000
M89.4 Other hypertrophic osteo-arthropathy
0.677 0.323 0.000
M24 Other specific joint derangements
0.675 0.325 0.000
E05.5 Thyroid crisis or storm
0.675 0.325 0.000
E05.4 Thyrotoxicosis factitia
0.675 0.325 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.675 0.325 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.675 0.325 0.000
M89.83 Other specified disorders of bone (Forearm)
0.675 0.325 0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)
0.674 0.326 0.000
E54 Ascorbic acid deficiency
0.673 0.327 0.000
M85 Other disorders of bone density and structure
0.672 0.328 0.000
M80 Osteoporosis with pathological fracture
0.672 0.328 0.000
E10-E14 Diabetes mellitus
0.671 0.329 0.000
M22.0 Recurrent dislocation of patella
0.670 0.330 0.000
M89.86 Other specified disorders of bone (Lower leg)
0.668 0.332 0.000
M25.3 Other instability of joint
0.667 0.333 0.000
E29 Testicular dysfunction
0.664 0.336 0.000
M88 Paget's disease of bone [osteitis deformans]
0.663 0.337 0.000
M33 Dermatopolymyositis
0.659 0.340 0.000
M84.0 Malunion of fracture
0.657 0.343 0.000
M96.8 Other postprocedural musculoskeletal disorders
0.655 0.345 0.000
V40-V49 Car occupant injured in transport accident
0.655 0.345 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.654 0.346 0.000
M89.81 Other specified disorders of bone (Shoulder region)
0.652 0.348 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.651 0.349 0.000
W50-W64 Exposure to animate mechanical forces
0.650 0.350 0.000
M42 Spinal osteochondrosis
0.649 0.351 0.000
M45-M49 Spondylopathies
0.648 0.352 0.000
M25.9 Joint disorder, unspecified
0.648 0.352 0.000
M43.9 Deforming dorsopathy, unspecified
0.647 0.353 0.000
M43.5 Other recurrent vertebral subluxation
0.647 0.353 0.000
M43.4 Other recurrent atlantoaxial subluxation
0.647 0.353 0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy
0.647 0.353 0.000
M43.2 Other fusion of spine
0.647 0.353 0.000
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)
0.643 0.357 0.000
M43.15 Spondylolisthesis (Thoracolumbar region)
0.643 0.357 0.000
M43.14 Spondylolisthesis (Thoracic region)
0.643 0.357 0.000
M43.13 Spondylolisthesis (Cervicothoracic region)
0.643 0.357 0.000
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)
0.643 0.357 0.000
M43.10 Spondylolisthesis (Multiple sites in spine)
0.643 0.357 0.000
M99 Biomechanical lesions, not elsewhere classified
0.643 0.357 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.642 0.358 0.000
M25.78 Osteophyte (Other)
0.640 0.360 0.000
M35.0 Sicca syndrome [Sjogren]
0.640 0.360 0.000
E51 Thiamine deficiency
0.638 0.361 0.000
M24.2 Disorder of ligament
0.638 0.362 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.638 0.362 0.000
M87.8 Other osteonecrosis
0.638 0.362 0.000
E29.1 Testicular hypofunction
0.635 0.365 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.634 0.366 0.000
M34 Systemic sclerosis
0.633 0.367 0.000
M84.03 Malunion of fracture (Forearm)
0.633 0.367 0.000
M87.0 Idiopathic aseptic necrosis of bone
0.631 0.369 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.631 0.369 0.000
E63 Other nutritional deficiencies
0.631 0.369 0.000
E56 Other vitamin deficiencies
0.631 0.369 0.000
E50 Vitamin A deficiency
0.631 0.369 0.000
E60 Dietary zinc deficiency
0.631 0.369 0.000
E59 Dietary selenium deficiency
0.631 0.369 0.000
E52 Niacin deficiency [pellagra]
0.631 0.369 0.000
M91-M94 Chondropathies
0.625 0.375 0.000
X20-X29 Contact with venomous animals and plants
0.622 0.378 0.000
E53.1 Pyridoxine deficiency
0.622 0.378 0.000
E53.0 Riboflavin deficiency
0.622 0.378 0.000
M25.72 Osteophyte (Upper arm)
0.622 0.378 0.000
M25.37 Other instability of joint (Ankle and foot)
0.622 0.378 0.000
W55 Bitten or struck by other mammals
0.622 0.378 0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)
0.622 0.378 0.000
E61.1 Iron deficiency
0.621 0.379 0.000
M83 Adult osteomalacia
0.619 0.380 0.000
M22.3 Other derangements of patella
0.617 0.383 0.000
M06 Other rheumatoid arthritis
0.617 0.383 0.000
M43.6 Torticollis
0.616 0.384 0.000
M62.9 Disorder of muscle, unspecified
0.615 0.385 0.000
M48 Other spondylopathies
0.613 0.387 0.000
W55.0 Home
0.610 0.390 0.000
M21.2 Flexion deformity
0.609 0.391 0.000
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate
0.608 0.392 0.000
M96.5 Postradiation scoliosis
0.608 0.392 0.000
M96.4 Postsurgical lordosis
0.608 0.392 0.000
M96.3 Postlaminectomy kyphosis
0.608 0.392 0.000
M96.2 Postradiation kyphosis
0.608 0.392 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.607 0.393 0.000
M61 Calcification and ossification of muscle
0.607 0.393 0.000
M62.84 Other specified disorders of muscle (Hand)
0.607 0.393 0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)
0.605 0.395 0.000
V10-V19 Pedal cyclist injured in transport accident
0.603 0.397 0.000
M22.9 Disorder of patella, unspecified
0.603 0.397 0.000
M30.0 Polyarteritis nodosa
0.602 0.398 0.000
M40 Kyphosis and lordosis
0.600 0.399 0.000
E58 Dietary calcium deficiency
0.600 0.400 0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.600 0.400 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.600 0.400 0.000
M62.83 Other specified disorders of muscle (Forearm)
0.599 0.401 0.000
M62.6 Muscle strain
0.597 0.403 0.000
M62.88 Other specified disorders of muscle (Other)
0.597 0.403 0.000
M31.9 Necrotising vasculopathy, unspecified
0.597 0.403 0.000
M31.8 Other specified necrotising vasculopathies
0.597 0.403 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.597 0.403 0.000
M31.2 Lethal midline granuloma
0.597 0.403 0.000
M31.0 Hypersensitivity angiitis
0.597 0.403 0.000
M84.3 Stress fracture, not elsewhere classified
0.597 0.403 0.000
M89.6 Osteopathy after poliomyelitis
0.595 0.405 0.000
M89.2 Other disorders of bone development and growth
0.595 0.405 0.000
M89.1 Epiphyseal arrest
0.595 0.405 0.000
M90 Osteopathies in diseases classified elsewhere
0.595 0.405 0.000
M89.5 Osteolysis
0.595 0.405 0.000
E65-E68 Obesity and other hyperalimentation
0.594 0.406 0.000
M22.1 Recurrent subluxation of patella
0.593 0.407 0.000
M65 Synovitis and tenosynovitis
0.590 0.410 0.000
E11 Non-insulin-dependent diabetes mellitus
0.590 0.410 0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)
0.590 0.410 0.000
M43.09 Spondylolysis (Site unspecified)
0.590 0.410 0.000
E61.2 Magnesium deficiency
0.589 0.411 0.000
M21.9 Acquired deformity of limb, unspecified
0.587 0.413 0.000
M62.82 Other specified disorders of muscle (Upper arm)
0.584 0.415 0.000
M43.12 Spondylolisthesis (Cervical region)
0.583 0.417 0.000
M21.7 Unequal limb length (acquired)
0.583 0.417 0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot
0.583 0.417 0.000
E06 Thyroiditis
0.581 0.419 0.000
V49 Car occupant injured in other and unspecified transport accidents
0.580 0.420 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.580 0.420 0.000
M85.6 Other cyst of bone
0.579 0.421 0.000
M89.88 Other specified disorders of bone (Other)
0.578 0.421 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.578 0.422 0.000
M60 Myositis
0.578 0.422 0.000
M84.8 Other disorders of continuity of bone
0.577 0.423 0.000
M62.4 Contracture of muscle
0.576 0.423 0.000
M62.3 Immobility syndrome (paraplegic)
0.576 0.423 0.000
M62.2 Ischaemic infarction of muscle
0.576 0.423 0.000
M62.1 Other rupture of muscle (nontraumatic)
0.576 0.423 0.000
M62.0 Diastasis of muscle
0.576 0.423 0.000
E53.9 Vitamin B deficiency, unspecified
0.576 0.424 0.000
M21.8 Other specified acquired deformities of limbs
0.576 0.424 0.000
M06.9 Rheumatoid arthritis, unspecified
0.575 0.425 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.574 0.426 0.000
M25.4 Effusion of joint
0.574 0.426 0.000
M87.98 Osteonecrosis, unspecified (Other)
0.573 0.427 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.572 0.428 0.000
M86 Osteomyelitis
0.572 0.428 0.000
Y00-Y09 Assault
0.572 0.428 0.000
Y85 Sequelae of transport accidents
0.571 0.429 0.000
X23 Contact with hornets, wasps and bees
0.571 0.429 0.000
M89.9 Disorder of bone, unspecified
0.570 0.430 0.000
M87.3 Other secondary osteonecrosis
0.570 0.430 0.000
M87.1 Osteonecrosis due to drugs
0.570 0.430 0.000
M89.89 Other specified disorders of bone (Site unspecified)
0.569 0.430 0.000
M89.82 Other specified disorders of bone (Upper arm)
0.569 0.430 0.000
M89.80 Other specified disorders of bone (Multiple sites)
0.569 0.430 0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified
0.569 0.431 0.000
E26 Hyperaldosteronism
0.569 0.431 0.000
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)
0.568 0.432 0.000
M89.84 Other specified disorders of bone (Hand)
0.567 0.432 0.000
E34 Other endocrine disorders
0.567 0.433 0.000
M43.08 Spondylolysis (Sacral and sacrococcygeal region)
0.566 0.434 0.000
M43.07 Spondylolysis (Lumbosacral region)
0.566 0.434 0.000
M43.05 Spondylolysis (Thoracolumbar region)
0.566 0.434 0.000
M43.04 Spondylolysis (Thoracic region)
0.566 0.434 0.000
M43.03 Spondylolysis (Cervicothoracic region)
0.566 0.434 0.000
M43.01 Spondylolysis (Occipito-atlanto-axial region)
0.566 0.434 0.000
M43.00 Spondylolysis (Multiple sites in spine)
0.566 0.434 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.566 0.434 0.000
D86.3 Sarcoidosis of skin
0.566 0.434 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.565 0.435 0.000
M25.79 Osteophyte (Site unspecified)
0.565 0.435 0.000
M24.26 Disorder of ligament (Lower leg)
0.564 0.436 0.000
M12 Other specific arthropathies
0.564 0.436 0.000
M48.0 Spinal stenosis
0.562 0.438 0.000
M89.0 Algoneurodystrophy
0.562 0.438 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.559 0.441 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.559 0.441 0.000
V48 Car occupant injured in noncollision transport accident
0.558 0.442 0.000
M62.81 Other specified disorders of muscle (Shoulder region)
0.557 0.443 0.000
M32 Systemic lupus erythematosus
0.557 0.443 0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)
0.556 0.444 0.000
E11.1 With ketoacidosis
0.554 0.446 0.000
Q00-Q07 Congenital malformations of the nervous system
0.554 0.446 0.000
M87.2 Osteonecrosis due to previous trauma
0.553 0.447 0.000
M43.86 Other specified deforming dorsopathies (Lumbar region)
0.551 0.448 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.551 0.449 0.000
M13 Other arthritis
0.551 0.449 0.000
M21.3 Wrist or foot drop (acquired)
0.550 0.450 0.000
M25.94 Joint disorder, unspecified (Hand)
0.549 0.451 0.000
M62.87 Other specified disorders of muscle (Ankle and foot)
0.549 0.451 0.000
D84 Other immunodeficiencies
0.548 0.452 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.548 0.452 0.000
M25.2 Flail joint
0.547 0.453 0.000
M25.1 Fistula of joint
0.547 0.453 0.000
E11.9 Without complications
0.546 0.454 0.000
E20 Hypoparathyroidism
0.545 0.455 0.000
M84.9 Disorder of continuity of bone, unspecified
0.544 0.456 0.000
M84.2 Delayed union of fracture
0.544 0.456 0.000
M96.9 Postprocedural musculoskeletal disorder, unspecified
0.543 0.457 0.000
M85.4 Solitary bone cyst
0.541 0.459 0.000
M00 Pyogenic arthritis
0.540 0.460 0.000
M95.2 Other acquired deformity of head
0.540 0.460 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.540 0.460 0.000
V19 Pedal cyclist injured in other and unspecified transport accidents
0.540 0.460 0.000
M30.8 Other conditions related to polyarteritis nodosa
0.537 0.463 0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
0.537 0.463 0.000
M30.2 Juvenile polyarteritis
0.537 0.463 0.000
M35.3 Polymyalgia rheumatica
0.537 0.463 0.000
E61.9 Deficiency of nutrient element, unspecified
0.536 0.464 0.000
E61.8 Deficiency of other specified nutrient elements
0.536 0.464 0.000
E61.7 Deficiency of multiple nutrient elements
0.536 0.464 0.000
E61.6 Vanadium deficiency
0.536 0.464 0.000
E61.5 Molybdenum deficiency
0.536 0.464 0.000
E61.4 Chromium deficiency
0.536 0.464 0.000
E61.3 Manganese deficiency
0.536 0.464 0.000
E61.0 Copper deficiency
0.536 0.464 0.000
E14 Unspecified diabetes mellitus
0.536 0.464 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.535 0.465 0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)
0.535 0.465 0.000
M89.3 Hypertrophy of bone
0.534 0.465 0.000
M87.91 Osteonecrosis, unspecified (Shoulder region)
0.533 0.467 0.000
E27 Other disorders of adrenal gland
0.533 0.467 0.000
Chapter XXII Codes for special purposes
0.532 0.468 0.000
Q76 Congenital malformations of spine and bony thorax
0.532 0.468 0.000
M89.87 Other specified disorders of bone (Ankle and foot)
0.531 0.469 0.000
Y52 Agents primarily affecting the cardiovascular system
0.531 0.469 0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)
0.529 0.471 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.529 0.471 0.000
Q25 Congenital malformations of great arteries
0.528 0.472 0.000
M25.73 Osteophyte (Forearm)
0.527 0.473 0.000
M25.70 Osteophyte (Multiple sites)
0.527 0.473 0.000
M24.27 Disorder of ligament (Ankle and foot)
0.526 0.474 0.000
W20-W49 Exposure to inanimate mechanical forces
0.526 0.474 0.000
M87.85 Other osteonecrosis (Pelvic region and thigh)
0.525 0.475 0.000
W75-W84 Other accidental threats to breathing
0.524 0.476 0.000
Y10-Y34 Event of undetermined intent
0.522 0.478 0.000
V95-V97 Air and space transport accidents
0.522 0.478 0.000
E11.0 With coma
0.521 0.479 0.000
M84.4 Pathological fracture, not elsewhere classified
0.521 0.479 0.000
E07 Other disorders of thyroid
0.520 0.480 0.000
M21.4 Flat foot [pes planus] (acquired)
0.520 0.480 0.000
M25.31 Other instability of joint (Shoulder region)
0.520 0.480 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.520 0.480 0.000
V01-V09 Pedestrian injured in transport accident
0.520 0.480 0.000
E65 Localised adiposity
0.520 0.480 0.000
E70-E90 Metabolic disorders
0.519 0.481 0.000
M81 Osteoporosis without pathological fracture
0.519 0.481 0.000
M21.19 Varus deformity, not elsewhere classified (Site unspecified)
0.518 0.482 0.000
M21.18 Varus deformity, not elsewhere classified (Other)
0.518 0.482 0.000
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)
0.518 0.482 0.000
M21.14 Varus deformity, not elsewhere classified (Hand)
0.518 0.482 0.000
M21.13 Varus deformity, not elsewhere classified (Forearm)
0.518 0.482 0.000
M21.12 Varus deformity, not elsewhere classified (Upper arm)
0.518 0.482 0.000
M21.11 Varus deformity, not elsewhere classified (Shoulder region)
0.518 0.482 0.000
M21.10 Varus deformity, not elsewhere classified (Multiple sites)
0.518 0.482 0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)
0.518 0.482 0.000
Q60-Q64 Congenital malformations of the urinary system
0.517 0.483 0.000
M24.5 Contracture of joint
0.517 0.483 0.000
E28 Ovarian dysfunction
0.516 0.483 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.516 0.484 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.516 0.484 0.000
M35.5 Multifocal fibrosclerosis
0.516 0.484 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.516 0.484 0.000
E22 Hyperfunction of pituitary gland
0.516 0.484 0.000
M24.28 Disorder of ligament (Other)
0.516 0.484 0.000
D50-D53 Nutritional anaemias
0.516 0.484 0.000
M35.7 Hypermobility syndrome
0.514 0.486 0.000
M87.05 Idiopathic aseptic necrosis of bone (Pelvic region and thigh)
0.514 0.486 0.000
D82 Immunodeficiency associated with other major defects
0.513 0.486 0.000
D81 Combined immunodeficiencies
0.513 0.486 0.000
M41 Scoliosis
0.513 0.487 0.000
E85 Amyloidosis
0.511 0.489 0.000
M84.01 Malunion of fracture (Shoulder region)
0.510 0.489 0.000
M87.96 Osteonecrosis, unspecified (Lower leg)
0.509 0.491 0.000
M06.4 Inflammatory polyarthropathy
0.509 0.491 0.000
V11 Pedal cyclist injured in collision with other pedal cycle
0.508 0.492 0.000
M84.02 Malunion of fracture (Upper arm)
0.508 0.492 0.000
E34.9 Endocrine disorder, unspecified
0.508 0.492 0.000
M24.7 Protrusio acetabuli
0.507 0.492 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.507 0.493 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.507 0.493 0.000
M07 Psoriatic and enteropathic arthropathies
0.506 0.494 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.506 0.494 0.000
E32 Diseases of thymus
0.506 0.494 0.000
E31 Polyglandular dysfunction
0.506 0.494 0.000
E30 Disorders of puberty, not elsewhere classified
0.506 0.494 0.000
E25 Adrenogenital disorders
0.506 0.494 0.000
M88.9 Paget's disease of bone, unspecified
0.506 0.494 0.000
W64 Exposure to other and unspecified animate mechanical forces
0.505 0.495 0.000
V70-V79 Bus occupant injured in transport accident
0.504 0.496 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.504 0.496 0.000
M08 Juvenile arthritis
0.504 0.496 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.503 0.497 0.000
M02 Reactive arthropathies
0.503 0.497 0.000
M34.1 CR(E)ST syndrome
0.503 0.497 0.000
M43.89 Other specified deforming dorsopathies (Site unspecified)
0.500 0.499 0.000
M43.88 Other specified deforming dorsopathies (Sacral and sacrococcygeal region)
0.500 0.499 0.000
M43.87 Other specified deforming dorsopathies (Lumbosacral region)
0.500 0.499 0.000
M43.85 Other specified deforming dorsopathies (Thoracolumbar region)
0.500 0.499 0.000
M43.84 Other specified deforming dorsopathies (Thoracic region)
0.500 0.499 0.000
M43.83 Other specified deforming dorsopathies (Cervicothoracic region)
0.500 0.499 0.000
M43.82 Other specified deforming dorsopathies (Cervical region)
0.500 0.499 0.000
M43.81 Other specified deforming dorsopathies (Occipito-atlanto-axial region)
0.500 0.499 0.000
M43.80 Other specified deforming dorsopathies (Multiple sites in spine)
0.500 0.499 0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.500 0.500 0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.500 0.500 0.000
V43 Car occupant injured in collision with car, pick-up truck or van
0.500 0.500 0.000
Q76.0 Spina bifida occulta
0.499 0.501 0.000
Y35-Y36 Legal intervention and operations of war
0.498 0.502 0.000
X85-X99 Assault
0.498 0.502 0.000
X30-X39 Exposure to forces of nature
0.498 0.502 0.000
W65-W74 Accidental drowning and submersion
0.498 0.502 0.000
V90-V94 Water transport accidents
0.498 0.502 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.498 0.502 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.498 0.502 0.000
M21.25 Flexion deformity (Pelvic region and thigh)
0.498 0.502 0.000
M48.09 Spinal stenosis (Site unspecified)
0.498 0.502 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.498 0.502 0.000
Y85.0 Sequelae of motor-vehicle accident
0.498 0.502 0.000
Y86 Sequelae of other accidents
0.496 0.504 0.000
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns
0.496 0.504 0.000
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other
0.496 0.504 0.000
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le
0.496 0.504 0.000
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t
0.496 0.504 0.000
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)
0.496 0.504 0.000
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm
0.496 0.504 0.000
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar
0.496 0.504 0.000
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re
0.496 0.504 0.000
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)
0.496 0.504 0.000
X23.0 Home
0.496 0.504 0.000
M94 Other disorders of cartilage
0.495 0.505 0.000
D51 Vitamin B12 deficiency anaemia
0.495 0.505 0.000
M89.94 Disorder of bone, unspecified (Hand)
0.494 0.506 0.000
M85.9 Disorder of bone density and structure, unspecified
0.494 0.506 0.000
V98-V99 Other and unspecified transport accidents
0.493 0.507 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.492 0.508 0.000
V44 Car occupant injured in collision with heavy transport vehicle or bus
0.491 0.509 0.000
W21 Striking against or struck by sports equipment
0.491 0.509 0.000
Q35-Q37 Cleft lip and cleft palate
0.490 0.509 0.000
M33.2 Polymyositis
0.490 0.510 0.000
X23.9 Unspecified place
0.490 0.510 0.000
Y89 Sequelae of other external causes
0.490 0.510 0.000
M21.27 Flexion deformity (Ankle and foot)
0.490 0.510 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.489 0.511 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.489 0.511 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.489 0.511 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.489 0.511 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.489 0.511 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.489 0.511 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.489 0.511 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.489 0.511 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.489 0.511 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.489 0.511 0.000
M87.99 Osteonecrosis, unspecified (Site unspecified)
0.488 0.512 0.000
M87.94 Osteonecrosis, unspecified (Hand)
0.488 0.512 0.000
M87.93 Osteonecrosis, unspecified (Forearm)
0.488 0.512 0.000
M87.92 Osteonecrosis, unspecified (Upper arm)
0.488 0.512 0.000
M87.90 Osteonecrosis, unspecified (Multiple sites)
0.488 0.512 0.000
M82 Osteoporosis in diseases classified elsewhere
0.487 0.512 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.487 0.513 0.000
M21.69 Other acquired deformities of ankle and foot-Site unspec
0.487 0.513 0.000
M21.68 Other acquired deformities of ankle and foot-Other
0.487 0.513 0.000
M21.66 Other acquired deformities of ankle and foot-Lower leg
0.487 0.513 0.000
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh
0.487 0.513 0.000
M21.64 Other acquired deformities of ankle and foot-Hand
0.487 0.513 0.000
M21.63 Other acquired deformities of ankle and foot-Forearm
0.487 0.513 0.000
M21.62 Other acquired deformities of ankle and foot-Upper arm
0.487 0.513 0.000
M21.61 Other acquired deformities of ankle and foot-Shldr region
0.487 0.513 0.000
M21.60 Other acquired deformities of ankle and foot-Mult sites
0.487 0.513 0.000
M85.2 Hyperostosis of skull
0.487 0.513 0.000
M35.1 Other overlap syndromes
0.486 0.514 0.000
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)
0.485 0.514 0.000
M89.48 Other hypertrophic osteoarthropathy (Other)
0.485 0.514 0.000
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)
0.485 0.514 0.000
M89.46 Other hypertrophic osteoarthropathy (Lower leg)
0.485 0.514 0.000
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)
0.485 0.514 0.000
M89.44 Other hypertrophic osteoarthropathy (Hand)
0.485 0.514 0.000
M89.43 Other hypertrophic osteoarthropathy (Forearm)
0.485 0.514 0.000
M89.42 Other hypertrophic osteoarthropathy (Upper arm)
0.485 0.514 0.000
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)
0.485 0.514 0.000
M43.06 Spondylolysis (Lumbar region)
0.485 0.515 0.000
M24.9 Joint derangement, unspecified
0.484 0.516 0.000
D83 Common variable immunodeficiency
0.484 0.516 0.000
E26.9 Hyperaldosteronism, unspecified
0.484 0.516 0.000
V19.3 Pedal cyclist [any] injured in an unspecified nontraffic accident
0.483 0.516 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.483 0.517 0.000
E85.4 Organ-limited amyloidosis
0.483 0.517 0.000
M25.36 Other instability of joint (Lower leg)
0.483 0.517 0.000
E11.3 With ophthalmic complications
0.483 0.517 0.000
E40-E46 Malnutrition
0.482 0.518 0.000
M85.5 Aneurysmal bone cyst
0.482 0.518 0.000
M85.3 Osteitis condensans
0.482 0.518 0.000
M85.1 Skeletal fluorosis
0.482 0.518 0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.482 0.518 0.000
M80.4 Drug-induced osteoporosis with pathological fracture
0.482 0.518 0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture
0.482 0.518 0.000
M80.2 Osteoporosis of disuse with pathological fracture
0.482 0.518 0.000
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)
0.481 0.518 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.481 0.519 0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)
0.481 0.519 0.000
M95.3 Acquired deformity of neck
0.481 0.519 0.000
E12 Malnutrition-related diabetes mellitus
0.481 0.519 0.000
M48.8 Other specified spondylopathies
0.481 0.519 0.000
E14.3 With ophthalmic complications
0.481 0.519 0.000
M25.97 Joint disorder, unspecified (Ankle and foot)
0.480 0.520 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.479 0.521 0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.479 0.521 0.000
M62.99 Disorder of muscle, unspecified (Site unspecified)
0.479 0.521 0.000
X00-X09 Exposure to smoke, fire and flames
0.479 0.521 0.000
M24.24 Disorder of ligament (Hand)
0.478 0.522 0.000
M25.39 Other instability of joint (Site unspecified)
0.478 0.522 0.000
M25.38 Other instability of joint (Other)
0.478 0.522 0.000
M25.35 Other instability of joint (Pelvic region and thigh)
0.478 0.522 0.000
M25.32 Other instability of joint (Upper arm)
0.478 0.522 0.000
M25.30 Other instability of joint (Multiple sites)
0.478 0.522 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.478 0.522 0.000
E29.9 Testicular dysfunction, unspecified
0.476 0.523 0.000
E29.8 Other testicular dysfunction
0.476 0.523 0.000
E29.0 Testicular hyperfunction
0.476 0.523 0.000
M85.64 Other cyst of bone (Hand)
0.476 0.524 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.476 0.524 0.000
M49 Spondylopathies in diseases classified elsewhere
0.475 0.524 0.000
M35.2 Behcet's disease
0.475 0.524 0.000
M88.8 Paget's disease of other bones
0.475 0.525 0.000
M88.0 Paget's disease of skull
0.475 0.525 0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)
0.475 0.525 0.000
M99.5 Intervertebral disk stenosis of neural canal
0.475 0.525 0.000
M33.1 Other dermatomyositis
0.473 0.527 0.000
M33.9 Dermatopolymyositis, unspecified
0.473 0.527 0.000
M33.0 Juvenile dermatomyositis
0.473 0.527 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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