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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74252946
log Bayes Factor = 13.4758
Chromosome 17   position 10,125,196  (GRCh37) Explore rs74252946 on Ensembl!
Variant rs74252946 is part of Cluster X0227

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
E70-E90 Metabolic disorders
0.998 0.002 0.000
R50-R69 General symptoms and signs
0.992 0.008 0.000
O60-O75 Complications of labour and delivery
0.990 0.010 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.990 0.010 0.000
I60-I69 Cerebrovascular diseases
0.987 0.013 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.987 0.013 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.985 0.015 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.980 0.020 0.000
R11 Nausea and vomiting
0.980 0.020 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.980 0.020 0.000
E83 Disorders of mineral metabolism
0.977 0.023 0.000
R13 Dysphagia
0.976 0.024 0.000
R63 Symptoms and signs concerning food and fluid intake
0.971 0.029 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.966 0.034 0.000
M70-M79 Other soft tissue disorders
0.963 0.037 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.960 0.040 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.957 0.043 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.955 0.045 0.000
R63.0 Anorexia
0.955 0.045 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.952 0.048 0.000
M75 Shoulder lesions
0.949 0.051 0.000
E20-E35 Disorders of other endocrine glands
0.946 0.054 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.944 0.056 0.000
S50-S59 Injuries to the elbow and forearm
0.940 0.060 0.000
I05-I09 Chronic rheumatic heart diseases
0.936 0.064 0.000
E83.4 Disorders of magnesium metabolism
0.934 0.066 0.000
R50 Fever of unknown origin
0.931 0.069 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.931 0.069 0.000
M75.4 Impingement syndrome of shoulder
0.928 0.072 0.000
O16 Unspecified maternal hypertension
0.927 0.073 0.000
R60 Oedema, not elsewhere classified
0.924 0.076 0.000
Chapter XX External causes of morbidity and mortality
0.923 0.077 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.923 0.077 0.000
Q60-Q64 Congenital malformations of the urinary system
0.922 0.078 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.921 0.079 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.918 0.082 0.000
I61 Intracerebral haemorrhage
0.918 0.082 0.000
E78.0 Pure hypercholesterolaemia
0.907 0.093 0.000
M20-M25 Other joint disorders
0.907 0.093 0.000
E87.2 Acidosis
0.907 0.093 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.907 0.093 0.000
O66 Other obstructed labour
0.903 0.097 0.000
Chapter VIII Diseases of the ear and mastoid process
0.901 0.099 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.901 0.099 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.899 0.101 0.000
F60-F69 Disorders of adult personality and behaviour
0.898 0.102 0.000
I08 Multiple valve diseases
0.897 0.103 0.000
F99-F99 Unspecified mental disorder
0.894 0.105 0.000
R94 Abnormal results of function studies
0.891 0.109 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.890 0.110 0.000
E00-E07 Disorders of thyroid gland
0.888 0.112 0.000
Q61 Cystic kidney disease
0.887 0.113 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.881 0.119 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.878 0.122 0.000
R52 Pain, not elsewhere classified
0.878 0.122 0.000
S52 Fracture of forearm
0.878 0.122 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.875 0.125 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.874 0.126 0.000
R02 Gangrene, not elsewhere classified
0.873 0.127 0.000
O72 Postpartum haemorrhage
0.871 0.129 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.868 0.132 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.866 0.133 0.000
F10.3 Withdrawal state
0.866 0.134 0.000
R60.0 Localised oedema
0.864 0.136 0.000
E83.1 Disorders of iron metabolism
0.864 0.136 0.000
M86-M90 Other osteopathies
0.863 0.137 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.862 0.138 0.000
I27 Other pulmonary heart diseases
0.862 0.138 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.860 0.140 0.000
R94.5 Abnormal results of liver function studies
0.860 0.140 0.000
F10.2 Dependence syndrome
0.858 0.142 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.856 0.144 0.000
E87.7 Fluid overload
0.856 0.144 0.000
S52.0 Fracture of upper end of ulna
0.855 0.145 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.850 0.150 0.000
R04 Haemorrhage from respiratory passages
0.849 0.151 0.000
M91-M94 Chondropathies
0.847 0.153 0.000
R50.9 Fever, unspecified
0.843 0.157 0.000
F10.1 Harmful use
0.843 0.157 0.000
I62 Other nontraumatic intracranial haemorrhage
0.843 0.157 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.843 0.157 0.000
T51 Toxic effect of alcohol
0.842 0.158 0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified
0.840 0.160 0.000
F17.1 Harmful use
0.840 0.160 0.000
S52.00 Fracture of upper end of ulna (closed)
0.839 0.161 0.000
S10-S19 Injuries to the neck
0.838 0.162 0.000
R07 Pain in throat and chest
0.838 0.162 0.000
K70-K77 Diseases of liver
0.838 0.162 0.000
S56 Injury of muscle and tendon at forearm level
0.836 0.164 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.836 0.164 0.000
R07.3 Other chest pain
0.832 0.168 0.000
M76 Enthesopathies of lower limb, excluding foot
0.830 0.170 0.000
E85 Amyloidosis
0.828 0.172 0.000
I27.2 Other secondary pulmonary hypertension
0.828 0.172 0.000
M75.0 Adhesive capsulitis of shoulder
0.827 0.173 0.000
M24 Other specific joint derangements
0.826 0.173 0.000
R68 Other general symptoms and signs
0.824 0.175 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.824 0.176 0.000
R52.2 Other chronic pain
0.822 0.178 0.000
H60-H62 Diseases of external ear
0.820 0.180 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.820 0.180 0.000
I77 Other disorders of arteries and arterioles
0.820 0.180 0.000
F99 Mental disorder, not otherwise specified
0.819 0.181 0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head
0.818 0.182 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.818 0.182 0.000
Chapter XI Diseases of the digestive system
0.817 0.183 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.817 0.183 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.815 0.185 0.000
R61 Hyperhidrosis
0.815 0.185 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.813 0.187 0.000
E27 Other disorders of adrenal gland
0.813 0.187 0.000
R63.4 Abnormal weight loss
0.812 0.188 0.000
I20-I25 Ischaemic heart diseases
0.809 0.191 0.000
R04.2 Haemoptysis
0.805 0.195 0.000
O85-O92 Complications predominantly related to the puerperium
0.804 0.196 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.803 0.197 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.803 0.197 0.000
K70 Alcoholic liver disease
0.803 0.197 0.000
Q61.2 Polycystic kidney, adult type
0.801 0.199 0.000
R45 Symptoms and signs involving emotional state
0.801 0.199 0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
0.801 0.199 0.000
I69 Sequelae of cerebrovascular disease
0.800 0.200 0.000
E50-E64 Other nutritional deficiencies
0.799 0.201 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.795 0.205 0.000
O73 Retained placenta and membranes, without haemorrhage
0.794 0.206 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.793 0.207 0.000
F11 Mental and behavioural disorders due to use of opioids
0.792 0.208 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.791 0.209 0.000
K74 Fibrosis and cirrhosis of liver
0.788 0.212 0.000
E07 Other disorders of thyroid
0.787 0.213 0.000
M21 Other acquired deformities of limbs
0.787 0.213 0.000
Q50-Q56 Congenital malformations of genital organs
0.786 0.214 0.000
R56 Convulsions, not elsewhere classified
0.785 0.215 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.785 0.215 0.000
F60 Specific personality disorders
0.778 0.222 0.000
T51.0 Ethanol
0.778 0.222 0.000
I24 Other acute ischaemic heart diseases
0.778 0.222 0.000
F80-F89 Disorders of psychological development
0.777 0.222 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.777 0.223 0.000
F30-F39 Mood [affective] disorders
0.776 0.224 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.773 0.227 0.000
E87.5 Hyperkalaemia
0.772 0.228 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.770 0.230 0.000
K72 Hepatic failure, not elsewhere classified
0.769 0.231 0.000
E40-E46 Malnutrition
0.769 0.231 0.000
Q61.3 Polycystic kidney, unspecified
0.767 0.233 0.000
E06 Thyroiditis
0.767 0.233 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.767 0.233 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.766 0.234 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.765 0.235 0.000
I74 Arterial embolism and thrombosis
0.765 0.235 0.000
E34 Other endocrine disorders
0.764 0.236 0.000
M30 Polyarteritis nodosa and related conditions
0.763 0.237 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.762 0.238 0.000
I67 Other cerebrovascular diseases
0.762 0.238 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.761 0.239 0.000
M35 Other systemic involvement of connective tissue
0.761 0.239 0.000
R50.0 Fever with chills
0.761 0.239 0.000
E83.3 Disorders of phosphorus metabolism
0.759 0.241 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.759 0.241 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.759 0.241 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.756 0.244 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.755 0.245 0.000
S40-S49 Injuries to the shoulder and upper arm
0.754 0.246 0.000
K74.6 Other and unspecified cirrhosis of liver
0.753 0.247 0.000
O62 Abnormalities of forces of labour
0.753 0.247 0.000
M75.1 Rotator cuff syndrome
0.753 0.247 0.000
O72.1 Other immediate postpartum haemorrhage
0.753 0.247 0.000
O40 Polyhydramnios
0.753 0.247 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.751 0.248 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.751 0.249 0.000
L40-L45 Papulosquamous disorders
0.751 0.249 0.000
M89 Other disorders of bone
0.751 0.249 0.000
S90-S99 Injuries to the ankle and foot
0.751 0.249 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.750 0.250 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.749 0.250 0.000
R01 Cardiac murmurs and other cardiac sounds
0.747 0.253 0.000
M34 Systemic sclerosis
0.746 0.254 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.746 0.254 0.000
O71 Other obstetric trauma
0.745 0.255 0.000
F69 Unspecified disorder of adult personality and behaviour
0.744 0.256 0.000
Chapter I Certain infectious and parasitic diseases
0.744 0.256 0.000
R57 Shock, not elsewhere classified
0.742 0.258 0.000
V80-V89 Other land transport accidents
0.742 0.258 0.000
I70 Atherosclerosis
0.741 0.259 0.000
K75 Other inflammatory liver diseases
0.740 0.260 0.000
H61 Other disorders of external ear
0.739 0.261 0.000
T79-T79 Certain early complications of trauma
0.739 0.261 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.739 0.261 0.000
O42 Premature rupture of membranes
0.738 0.262 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.737 0.263 0.000
M75.9 Shoulder lesion, unspecified
0.737 0.263 0.000
K73 Chronic hepatitis, not elsewhere classified
0.737 0.263 0.000
M76.6 Achilles tendinitis
0.735 0.264 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.735 0.265 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.734 0.266 0.000
R45.1 Restlessness and agitation
0.734 0.266 0.000
H90-H95 Other disorders of ear
0.732 0.268 0.000
Q61.0 Congenital single renal cyst
0.731 0.269 0.000
I61.8 Other intracerebral haemorrhage
0.731 0.269 0.000
E78.4 Other hyperlipidaemia
0.731 0.269 0.000
O30 Multiple gestation
0.730 0.269 0.000
I78 Diseases of capillaries
0.730 0.270 0.000
S56.4 Injury of extensor muscle and tendon of other finger(s) at forearm level
0.730 0.270 0.000
T39.1 4-Aminophenol derivatives
0.730 0.270 0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.730 0.270 0.000
R50.8 Other specified fever
0.729 0.271 0.000
F01 Vascular dementia
0.729 0.271 0.000
E23 Hypofunction and other disorders of pituitary gland
0.728 0.272 0.000
O47 False labour
0.728 0.272 0.000
O41 Other disorders of amniotic fluid and membranes
0.728 0.272 0.000
M80-M85 Disorders of bone density and structure
0.727 0.273 0.000
O43 Placental disorders
0.726 0.274 0.000
O61 Failed induction of labour
0.725 0.275 0.000
I24.8 Other forms of acute ischaemic heart disease
0.725 0.275 0.000
O48 Prolonged pregnancy
0.724 0.276 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.724 0.276 0.000
F20 Schizophrenia
0.724 0.276 0.000
E78.8 Other disorders of lipoprotein metabolism
0.723 0.277 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.722 0.278 0.000
E04 Other non-toxic goitre
0.722 0.278 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.720 0.279 0.000
V40-V49 Car occupant injured in transport accident
0.720 0.280 0.000
W20-W49 Exposure to inanimate mechanical forces
0.720 0.280 0.000
R14 Flatulence and related conditions
0.720 0.280 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.719 0.281 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
L50-L54 Urticaria and erythema
0.716 0.284 0.000
E07.9 Disorder of thyroid, unspecified
0.715 0.285 0.000
E84 Cystic fibrosis
0.715 0.285 0.000
E79 Disorders of purine and pyrimidine metabolism
0.715 0.285 0.000
E77 Disorders of glycoprotein metabolism
0.715 0.285 0.000
E76 Disorders of glycosaminoglycan metabolism
0.715 0.285 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.715 0.285 0.000
E74 Other disorders of carbohydrate metabolism
0.715 0.285 0.000
E73 Lactose intolerance
0.715 0.285 0.000
E72 Other disorders of amino-acid metabolism
0.715 0.285 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.715 0.285 0.000
E70 Disorders of aromatic amino-acid metabolism
0.715 0.285 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.715 0.285 0.000
R05 Cough
0.715 0.285 0.000
O70 Perineal laceration during delivery
0.715 0.285 0.000
E28 Ovarian dysfunction
0.715 0.285 0.000
K70.0 Alcoholic fatty liver
0.712 0.288 0.000
O14.9 Preeclampsia, unspecified
0.711 0.289 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.711 0.289 0.000
R62 Lack of expected normal physiological development
0.711 0.289 0.000
R64 Cachexia
0.711 0.289 0.000
I77.0 Arteriovenous fistula, acquired
0.711 0.289 0.000
M24.0 Loose body in joint
0.711 0.289 0.000
O74 Complications of anaesthesia during labour and delivery
0.710 0.290 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.710 0.290 0.000
O60 Preterm delivery
0.710 0.290 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.709 0.290 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.709 0.290 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.709 0.290 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.709 0.290 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.709 0.290 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.709 0.290 0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.709 0.290 0.000
K59.0 Constipation
0.709 0.291 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.709 0.291 0.000
Q00-Q07 Congenital malformations of the nervous system
0.708 0.292 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.708 0.292 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.708 0.292 0.000
K70.3 Alcoholic cirrhosis of liver
0.708 0.292 0.000
I65.2 Occlusion and stenosis of carotid artery
0.707 0.293 0.000
R53 Malaise and fatigue
0.707 0.293 0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.706 0.294 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.706 0.294 0.000
E24 Cushing's syndrome
0.705 0.295 0.000
E21.3 Hyperparathyroidism, unspecified
0.705 0.295 0.000
M60-M63 Disorders of muscles
0.705 0.295 0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)
0.704 0.296 0.000
F31 Bipolar affective disorder
0.703 0.297 0.000
O15 Eclampsia
0.703 0.297 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.703 0.297 0.000
T33-T35 Frostbite
0.702 0.297 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.702 0.297 0.000
T00-T07 Injuries involving multiple body regions
0.702 0.297 0.000
X60-X84 Intentional self-harm
0.702 0.298 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.701 0.299 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.700 0.299 0.000
E83.8 Other disorders of mineral metabolism
0.700 0.299 0.000
E83.2 Disorders of zinc metabolism
0.700 0.299 0.000
E83.0 Disorders of copper metabolism
0.700 0.299 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.698 0.302 0.000
M00-M03 Infectious arthropathies
0.697 0.303 0.000
M50-M54 Other dorsopathies
0.696 0.304 0.000
R63.1 Polydipsia
0.696 0.304 0.000
R63.6 Insufficient intake of food and water due to self neglect
0.696 0.304 0.000
R63.5 Abnormal weight gain
0.696 0.304 0.000
R63.3 Feeding difficulties and mismanagement
0.696 0.304 0.000
R63.2 Polyphagia
0.696 0.304 0.000
K59 Other functional intestinal disorders
0.696 0.304 0.000
M92 Other juvenile osteochondrosis
0.696 0.304 0.000
E89.2 Postprocedural hypoparathyroidism
0.695 0.305 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.695 0.305 0.000
K55-K64 Other diseases of intestines
0.694 0.306 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.693 0.307 0.000
Q35-Q37 Cleft lip and cleft palate
0.693 0.307 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.693 0.307 0.000
M22 Disorders of patella
0.693 0.307 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.692 0.308 0.000
M35.0 Sicca syndrome [Sjogren]
0.692 0.308 0.000
M86 Osteomyelitis
0.692 0.308 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.690 0.310 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.690 0.310 0.000
T58 Toxic effect of carbon monoxide
0.690 0.310 0.000
Q63 Other congenital malformations of kidney
0.689 0.311 0.000
R60.9 Oedema, unspecified
0.689 0.311 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.689 0.311 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.689 0.311 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.689 0.311 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.689 0.311 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.689 0.311 0.000
T36 Poisoning by systemic antibiotics
0.689 0.311 0.000
R61.9 Hyperhidrosis, unspecified
0.688 0.312 0.000
O21 Excessive vomiting in pregnancy
0.687 0.313 0.000
F10.9 Unspecified mental and behavioural disorder
0.686 0.313 0.000
F10.8 Other mental and behavioural disorders
0.686 0.313 0.000
F10.7 Residual and late-onset psychotic disorder
0.686 0.313 0.000
F10.6 Amnesic syndrome
0.686 0.313 0.000
F10.5 Psychotic disorder
0.686 0.313 0.000
M65-M68 Disorders of synovium and tendon
0.686 0.314 0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
0.686 0.314 0.000
H61.0 Perichondritis of external ear
0.686 0.314 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.686 0.314 0.000
M75.2 Bicipital tendinitis
0.685 0.315 0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.685 0.315 0.000
F29 Unspecified nonorganic psychosis
0.685 0.315 0.000
E83.5 Disorders of calcium metabolism
0.685 0.315 0.000
M94 Other disorders of cartilage
0.684 0.316 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.684 0.316 0.000
T40.6 Other and unspecified narcotics
0.683 0.317 0.000
R60.1 Generalised oedema
0.683 0.317 0.000
K72.9 Hepatic failure, unspecified
0.683 0.317 0.000
T51.9 Alcohol, unspecified
0.683 0.317 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.683 0.317 0.000
E87.4 Mixed disorder of acid-base balance
0.682 0.317 0.000
Chapter XXII Codes for special purposes
0.682 0.317 0.000
X20-X29 Contact with venomous animals and plants
0.682 0.318 0.000
I63 Cerebral infarction
0.682 0.318 0.000
R68.0 Hypothermia, not associated with low environmental temperature
0.682 0.318 0.000
O86 Other puerperal infections
0.682 0.318 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.681 0.319 0.000
M75.8 Other shoulder lesions
0.680 0.319 0.000
R94.4 Abnormal results of kidney function studies
0.680 0.320 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.679 0.321 0.000
R06 Abnormalities of breathing
0.679 0.321 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.678 0.322 0.000
E32 Diseases of thymus
0.678 0.322 0.000
E31 Polyglandular dysfunction
0.678 0.322 0.000
E30 Disorders of puberty, not elsewhere classified
0.678 0.322 0.000
E25 Adrenogenital disorders
0.678 0.322 0.000
E20 Hypoparathyroidism
0.678 0.322 0.000
I61.5 Intracerebral haemorrhage, intraventricular
0.677 0.323 0.000
F60.3 Emotionally unstable personality disorder
0.677 0.323 0.000
M71 Other bursopathies
0.677 0.323 0.000
R15 Faecal incontinence
0.677 0.323 0.000
O24 Diabetes mellitus in pregnancy
0.676 0.324 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.676 0.324 0.000
Q80-Q89 Other congenital malformations
0.675 0.325 0.000
M89.9 Disorder of bone, unspecified
0.675 0.325 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.675 0.325 0.000
S59 Other and unspecified injuries of forearm
0.674 0.326 0.000
S58 Traumatic amputation of forearm
0.674 0.326 0.000
S57 Crushing injury of forearm
0.674 0.326 0.000
S55 Injury of blood vessels at forearm level
0.674 0.326 0.000
S54 Injury of nerves at forearm level
0.674 0.326 0.000
K76 Other diseases of liver
0.674 0.326 0.000
M77 Other enthesopathies
0.674 0.326 0.000
E22 Hyperfunction of pituitary gland
0.674 0.326 0.000
L40 Psoriasis
0.673 0.327 0.000
E89.3 Postprocedural hypopituitarism
0.672 0.328 0.000
E26 Hyperaldosteronism
0.671 0.328 0.000
M40-M43 Deforming dorsopathies
0.671 0.329 0.000
I09 Other rheumatic heart diseases
0.671 0.329 0.000
I06 Rheumatic aortic valve diseases
0.671 0.329 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.670 0.330 0.000
Y86 Sequelae of other accidents
0.670 0.330 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.669 0.331 0.000
R59 Enlarged lymph nodes
0.669 0.331 0.000
S56.1 Injury of flexor muscle and tendon of other finger(s) at forearm level
0.668 0.331 0.000
R16.1 Splenomegaly, not elsewhere classified
0.668 0.332 0.000
R50.2 Drug-induced fever
0.668 0.332 0.000
R50.1 Persistent fever
0.668 0.332 0.000
I07 Rheumatic tricuspid valve diseases
0.667 0.332 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.667 0.333 0.000
O97 Death from sequelae of direct obstetric causes
0.667 0.333 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.667 0.333 0.000
O95 Obstetric death of unspecified cause
0.667 0.333 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.667 0.333 0.000
O63 Long labour
0.667 0.333 0.000
S52.6 Fracture of lower end of both ulna and radius
0.667 0.333 0.000
X50-X57 Overexertion, travel and privation
0.667 0.333 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.667 0.333 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.666 0.334 0.000
E06.3 Autoimmune thyroiditis
0.666 0.334 0.000
O72.0 Third-stage haemorrhage
0.665 0.335 0.000
A00-A09 Intestinal infectious diseases
0.665 0.335 0.000
I74.5 Embolism and thrombosis of iliac artery
0.665 0.335 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.665 0.335 0.000
Y65 Other misadventures during surgical and medical care
0.664 0.336 0.000
E85.4 Organ-limited amyloidosis
0.664 0.336 0.000
Y88 Sequelae of surgical and medical care as external cause
0.664 0.336 0.000
E53 Deficiency of other B group vitamins
0.664 0.336 0.000
S10 Superficial injury of neck
0.663 0.337 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.663 0.337 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.663 0.337 0.000
Y35-Y36 Legal intervention and operations of war
0.662 0.338 0.000
Y10-Y34 Event of undetermined intent
0.662 0.338 0.000
Y00-Y09 Assault
0.662 0.338 0.000
X85-X99 Assault
0.662 0.338 0.000
X30-X39 Exposure to forces of nature
0.662 0.338 0.000
X10-X19 Contact with heat and hot substances
0.662 0.338 0.000
X00-X09 Exposure to smoke, fire and flames
0.662 0.338 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.662 0.338 0.000
W75-W84 Other accidental threats to breathing
0.662 0.338 0.000
W65-W74 Accidental drowning and submersion
0.662 0.338 0.000
W50-W64 Exposure to animate mechanical forces
0.662 0.338 0.000
V98-V99 Other and unspecified transport accidents
0.662 0.338 0.000
V95-V97 Air and space transport accidents
0.662 0.338 0.000
V90-V94 Water transport accidents
0.662 0.338 0.000
V70-V79 Bus occupant injured in transport accident
0.662 0.338 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.662 0.338 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.662 0.338 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.662 0.338 0.000
V01-V09 Pedestrian injured in transport accident
0.662 0.338 0.000
Q64 Other congenital malformations of urinary system
0.661 0.339 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.661 0.339 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.661 0.339 0.000
E78.6 Lipoprotein deficiency
0.660 0.339 0.000
E78.3 Hyperchylomicronaemia
0.660 0.339 0.000
E78.1 Pure hyperglyceridaemia
0.660 0.339 0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.659 0.341 0.000
O45 Premature separation of placenta [abruptio placentae]
0.658 0.342 0.000
O33 Maternal care for known or suspected disproportion
0.658 0.342 0.000
O31 Complications specific to multiple gestation
0.658 0.342 0.000
I61.6 Intracerebral haemorrhage, multiple localised
0.658 0.342 0.000
I61.4 Intracerebral haemorrhage in cerebellum
0.658 0.342 0.000
I61.3 Intracerebral haemorrhage in brain stem
0.658 0.342 0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.658 0.342 0.000
T39.0 Salicylates
0.657 0.342 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.657 0.342 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.657 0.343 0.000
H60 Otitis externa
0.657 0.343 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.657 0.343 0.000
K63 Other diseases of intestine
0.656 0.344 0.000
B35-B49 Mycoses
0.656 0.344 0.000
E85.9 Amyloidosis, unspecified
0.656 0.344 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.655 0.344 0.000
V20-V29 Motorcycle rider injured in transport accident
0.654 0.346 0.000
M45-M49 Spondylopathies
0.654 0.346 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.654 0.346 0.000
S53.3 Traumatic rupture of ulnar collateral ligament
0.653 0.346 0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
0.653 0.347 0.000
F03 Unspecified dementia
0.652 0.348 0.000
F11.2 Dependence syndrome
0.651 0.349 0.000
R18 Ascites
0.651 0.349 0.000
E29 Testicular dysfunction
0.650 0.349 0.000
D50-D53 Nutritional anaemias
0.651 0.349 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.650 0.350 0.000
M33 Dermatopolymyositis
0.650 0.350 0.000
M32 Systemic lupus erythematosus
0.650 0.350 0.000
I67.1 Cerebral aneurysm, nonruptured
0.650 0.350 0.000
I28 Other diseases of pulmonary vessels
0.650 0.350 0.000
L43 Lichen planus
0.650 0.350 0.000
R45.8 Other symptoms and signs involving emotional state
0.649 0.350 0.000
M90 Osteopathies in diseases classified elsewhere
0.649 0.351 0.000
S11 Open wound of neck
0.649 0.351 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.649 0.351 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.649 0.351 0.000
O66.9 Obstructed labour, unspecified
0.647 0.353 0.000
O66.8 Other specified obstructed labour
0.647 0.353 0.000
O66.4 Failed trial of labour, unspecified
0.647 0.353 0.000
O66.3 Obstructed labour due to other abnormalities of foetus
0.647 0.353 0.000
O66.2 Obstructed labour due to unusually large foetus
0.647 0.353 0.000
O66.1 Obstructed labour due to locked twins
0.647 0.353 0.000
O66.0 Obstructed labour due to shoulder dystocia
0.647 0.353 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.646 0.354 0.000
I73 Other peripheral vascular diseases
0.646 0.354 0.000
I22 Subsequent myocardial infarction
0.646 0.354 0.000
K72.0 Acute and subacute hepatic failure
0.646 0.354 0.000
T65 Toxic effect of other and unspecified substances
0.646 0.354 0.000
T62 Toxic effect of other noxious substances eaten as food
0.646 0.354 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.646 0.354 0.000
T60 Toxic effect of pesticides
0.646 0.354 0.000
T59 Toxic effect of other gases, fumes and vapours
0.646 0.354 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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