TreeWAS – Variant ID: rs743446

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T36-T50 Poisoning by drugs, medicaments and biological substances	0.216	0.784	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.206	0.793	0.000
T42.4 Benzodiazepines	0.204	0.796	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.198	0.802	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.197	0.803	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.191	0.809	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.191	0.809	0.000
T36 Poisoning by systemic antibiotics	0.188	0.812	0.000
T42.1 Iminostilbenes	0.185	0.815	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.179	0.821	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.175	0.825	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.174	0.826	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.172	0.828	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.170	0.830	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.164	0.836	0.000
T38.1 Thyroid hormones and substitutes	0.162	0.838	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.160	0.840	0.000
T47.0 Histamine H(2)-receptor antagonists	0.159	0.841	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.157	0.843	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.157	0.843	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.157	0.843	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.156	0.844	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.155	0.845	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.155	0.845	0.000
T50.4 Drugs affecting uric acid metabolism	0.154	0.846	0.000
T42.3 Barbiturates	0.152	0.848	0.000
T38.5 Other oestrogens and progestogens	0.152	0.848	0.000
T46.1 Calcium-channel blockers	0.151	0.849	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.150	0.850	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.150	0.850	0.000
T36.8 Other systemic antibiotics	0.149	0.851	0.000
T39.0 Salicylates	0.148	0.852	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.148	0.852	0.000
T42.2 Succinimides and oxazolidinediones	0.148	0.852	0.000
T36.4 Tetracyclines	0.148	0.852	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.148	0.852	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.146	0.854	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.145	0.855	0.000
T36.0 Penicillins	0.145	0.855	0.000
T47.6 Antidiarrhoeal drugs	0.144	0.855	0.000
T47.2 Stimulant laxatives	0.144	0.856	0.000
T47.4 Other laxatives	0.144	0.856	0.000
T45.2 Vitamins, not elsewhere classified	0.144	0.856	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.143	0.857	0.000
T36.3 Macrolides	0.142	0.857	0.000
T38.9 Other and unspecified hormone antagonists	0.142	0.858	0.000
T38.7 Androgens and anabolic congeners	0.142	0.858	0.000
T38.4 Oral contraceptives	0.142	0.858	0.000
T38.2 Antithyroid drugs	0.142	0.858	0.000
T38.0 Glucocorticoids and synthetic analogues	0.142	0.858	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.141	0.859	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.141	0.859	0.000
T47.7 Emetics	0.141	0.859	0.000
T47.5 Digestants	0.141	0.859	0.000
T47.3 Saline and osmotic laxatives	0.141	0.859	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.140	0.860	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.139	0.861	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.139	0.861	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.138	0.862	0.000
T50.7 Analeptics and opioid receptor antagonists	0.137	0.863	0.000
T50.5 Appetite depressants	0.137	0.863	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.137	0.863	0.000
T50.1 Loop [high-ceiling] diuretics	0.137	0.863	0.000
T50.0 Mineralocorticoids and their antagonists	0.137	0.863	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.137	0.863	0.000
T46.7 Peripheral vasodilators	0.137	0.863	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.136	0.864	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.135	0.865	0.000
T36.9 Systemic antibiotic, unspecified	0.135	0.865	0.000
T36.7 Antifungal antibiotics, systemically used	0.135	0.865	0.000
T36.6 Rifamycins	0.135	0.865	0.000
T36.5 Aminoglycosides	0.135	0.865	0.000
T36.2 Chloramphenicol group	0.135	0.865	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.135	0.865	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.134	0.866	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.132	0.868	0.000
T45.5 Anticoagulants	0.129	0.871	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.129	0.871	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.129	0.871	0.000
T37.5 Antiviral drugs	0.129	0.871	0.000
T37.4 Anthelminthics	0.129	0.871	0.000
T37.3 Other antiprotozoal drugs	0.129	0.871	0.000
T37.1 Antimycobacterial drugs	0.129	0.871	0.000
T37.0 Sulphonamides	0.129	0.871	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.127	0.873	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.126	0.874	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.126	0.874	0.000
T45.8 Other primarily systemic and haematological agents	0.126	0.874	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.126	0.874	0.000
T45.6 Fibrinolysis-affecting drugs	0.126	0.874	0.000
T45.4 Iron and its compounds	0.126	0.874	0.000
T45.3 Enzymes, not elsewhere classified	0.126	0.874	0.000
T43.6 Psychostimulants with abuse potential	0.124	0.875	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.124	0.876	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.122	0.878	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.122	0.878	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.122	0.878	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.122	0.878	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.122	0.878	0.000
T44.0 Anticholinesterase agents	0.122	0.878	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.122	0.878	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.120	0.880	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.120	0.880	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.119	0.881	0.000
T45.0 Antiallergic and antiemetic drugs	0.118	0.882	0.000
T43.9 Psychotropic drug, unspecified	0.116	0.884	0.000
T42.0 Hydantoin derivatives	0.115	0.885	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.115	0.885	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.113	0.887	0.000
T49.9 Topical agent, unspecified	0.113	0.887	0.000
T49.8 Other topical agents	0.113	0.887	0.000
T49.7 Dental drugs, topically applied	0.113	0.887	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.113	0.887	0.000
T49.5 Ophthalmological drugs and preparations	0.113	0.887	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.113	0.887	0.000
T49.3 Emollients, demulcents and protectants	0.113	0.887	0.000
T49.2 Local astringents and local detergents	0.113	0.887	0.000
T49.1 Antipruritics	0.113	0.887	0.000
T39.4 Antirheumatics, not elsewhere classified	0.113	0.887	0.000
T39.2 Pyrazolone derivatives	0.113	0.887	0.000
T41.5 Therapeutic gases	0.111	0.889	0.000
T41.4 Anaesthetic, unspecified	0.111	0.889	0.000
T41.3 Local anaesthetics	0.111	0.889	0.000
T41.2 Other and unspecified general anaesthetics	0.111	0.889	0.000
T41.1 Intravenous anaesthetics	0.111	0.889	0.000
T41.0 Inhaled anaesthetics	0.111	0.889	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.106	0.894	0.000
T48.5 Anti-common-cold drugs	0.106	0.894	0.000
T48.4 Expectorants	0.106	0.894	0.000
T48.3 Antitussives	0.106	0.894	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.106	0.894	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.106	0.894	0.000
T48.0 Oxytocic drugs	0.106	0.894	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.104	0.896	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.102	0.898	0.000
T43.2 Other and unspecified antidepressants	0.102	0.898	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.099	0.900	0.000
T50.8 Diagnostic agents	0.097	0.902	0.000
T40.1 Heroin	0.095	0.905	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.093	0.907	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.093	0.907	0.000
T40.8 Lysergide [LSD]	0.093	0.907	0.000
T40.7 Cannabis (derivatives)	0.093	0.907	0.000
T40.0 Opium	0.093	0.907	0.000
T40.6 Other and unspecified narcotics	0.091	0.909	0.000
T40.3 Methadone	0.091	0.909	0.000
T40.4 Other synthetic narcotics	0.091	0.909	0.000
T40.5 Cocaine	0.087	0.913	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.083	0.917	0.000
I42.9 Cardiomyopathy, unspecified	0.080	0.920	0.000
T40.2 Other opioids	0.079	0.921	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.073	0.927	0.000
I42 Cardiomyopathy	0.073	0.927	0.000
I42.2 Other hypertrophic cardiomyopathy	0.067	0.933	0.000
I42.0 Dilated cardiomyopathy	0.065	0.935	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.063	0.937	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.062	0.938	0.000
I42.4 Endocardial fibroelastosis	0.058	0.942	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.943	0.057
I42.5 Other restrictive cardiomyopathy	0.052	0.947	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.052	0.947	0.000
I42.8 Other cardiomyopathies	0.052	0.948	0.000
I42.6 Alcoholic cardiomyopathy	0.049	0.950	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.049	0.951	0.000
T39.1 4-Aminophenol derivatives	0.048	0.952	0.000
I69 Sequelae of cerebrovascular disease	0.000	0.957	0.043
I69.3 Sequelae of cerebral infarction	0.000	0.958	0.042
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.966	0.034
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.968	0.032
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.972	0.028
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.975	0.025
D04.3 Skin of other and unspecified parts of face	0.022	0.978	0.000
D04 Carcinoma in situ of skin	0.020	0.980	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.981	0.019
Z71.8 Other specified counselling	0.018	0.982	0.000
D04.6 Skin of upper limb, including shoulder	0.018	0.982	0.000
D04.7 Skin of lower limb, including hip	0.017	0.983	0.000
N87.1 Moderate cervical dysplasia	0.000	0.983	0.017
D04.5 Skin of trunk	0.016	0.984	0.000
E04.9 Non-toxic goitre, unspecified	0.016	0.984	0.000
D04.4 Skin of scalp and neck	0.016	0.984	0.000
D04.9 Skin, unspecified	0.015	0.985	0.000
D04.8 Skin of other sites	0.014	0.986	0.000
D04.0 Skin of lip	0.014	0.986	0.000
Z71.9 Counselling, unspecified	0.014	0.986	0.000
D04.1 Skin of eyelid, including canthus	0.014	0.986	0.000
F42.9 Obsessive-compulsive disorder, unspecified	0.013	0.987	0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.012	0.988	0.000
N87.2 Severe cervical dysplasia, not elsewhere classified	0.000	0.989	0.011
N87 Dysplasia of cervix uteri	0.000	0.989	0.011
D04.2 Skin of ear and external auricular canal	0.010	0.990	0.000
Z71.4 Alcohol abuse counselling and surveillance	0.010	0.990	0.000
N87.0 Mild cervical dysplasia	0.000	0.991	0.009
Z71.7 Human immunodeficiency virus [HIV] counselling	0.009	0.991	0.000
Z71.5 Drug abuse counselling and surveillance	0.009	0.991	0.000
Z71.0 Person consulting on behalf of another person	0.009	0.991	0.000
Z71.2 Person consulting for explanation of investigation findings	0.009	0.991	0.000
F42 Obsessive-compulsive disorder	0.008	0.992	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.008	0.992	0.000
Z75.8 Other problems related to medical facilities and other health care	0.007	0.992	0.000
Z71.6 Tobacco abuse counselling	0.007	0.993	0.000
F42.2 Mixed obsessional thoughts and acts	0.007	0.993	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.007	0.993	0.000
F42.1 Predominantly compulsive acts [obsessional rituals]	0.007	0.993	0.000
F42.0 Predominantly obsessional thoughts or ruminations	0.006	0.993	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.006	0.994	0.000
F42.8 Other obsessive-compulsive disorders	0.006	0.994	0.000
Z75 Problems related to medical facilities and other health care	0.006	0.994	0.000
Z29.0 Isolation	0.006	0.994	0.000
D61.9 Aplastic anaemia, unspecified	0.000	0.994	0.006
Z71.1 Person with feared complaint in whom no diagnosis is made	0.006	0.994	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.005	0.994	0.000
Z75.3 Unavailability and inaccessibility of health-care facilities	0.005	0.994	0.000
Z83.5 Family history of eye and ear disorders	0.000	0.994	0.006
D89.1 Cryoglobulinaemia	0.005	0.995	0.000
Z75.1 Person awaiting admission to adequate facility elsewhere	0.005	0.995	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.005	0.995	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.005	0.995	0.000
D89.3 Immune reconstitution syndrome	0.005	0.995	0.000
G81.9 Hemiplegia, unspecified	0.000	0.995	0.005
Z75.4 Unavailability and inaccessibility of other helping agencies	0.005	0.995	0.000
I87.1 Compression of vein	0.005	0.995	0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.005	0.995	0.000
Z29.2 Other prophylactic chemotherapy	0.005	0.995	0.000
Y60.0 During surgical operation	0.000	0.995	0.005
Z75.9 Unspecified problem related to medical facilities and other health care	0.005	0.995	0.000
Z29 Need for other prophylactic measures	0.005	0.995	0.000
M79.19 Myalgia (Site unspecified)	0.000	0.995	0.005
D09.0 Bladder	0.005	0.995	0.000
Z70-Z76 Persons encountering health services in other circumstances	0.005	0.995	0.000
Z75.5 Holiday relief care	0.004	0.995	0.000
Z75.0 Medical services not available in home	0.004	0.995	0.000
R12 Heartburn	0.004	0.996	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.004	0.996	0.000
D09 Carcinoma in situ of other and unspecified sites	0.004	0.996	0.000
D00-D09 In situ neoplasms	0.004	0.996	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.004	0.996	0.000
Z29.1 Prophylactic immunotherapy	0.004	0.996	0.000
Z75.2 Other waiting period for investigation and treatment	0.004	0.996	0.000
D02 Carcinoma in situ of middle ear and respiratory system	0.004	0.996	0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.004	0.996	0.000
I87 Other disorders of veins	0.004	0.996	0.000
C43.6 Malignant melanoma of upper limb, including shoulder	0.000	0.996	0.004
M23.49 Loose body in knee-Unspec lig/men	0.000	0.996	0.004
M79.10 Myalgia (Multiple sites)	0.000	0.996	0.004
G31.9 Degenerative disease of nervous system, unspecified	0.004	0.996	0.000
F44.9 Dissociative [conversion] disorder, unspecified	0.004	0.996	0.000
M85.0 Fibrous dysplasia (monostotic)	0.004	0.996	0.000
Z29.9 Prophylactic measure, unspecified	0.004	0.996	0.000
D02.0 Larynx	0.004	0.996	0.000
H44.2 Degenerative myopia	0.000	0.996	0.004
Z70 Counselling related to sexual attitude, behaviour and orientation	0.004	0.996	0.000
D00.0 Lip, oral cavity and pharynx	0.004	0.996	0.000
D80-D89 Certain disorders involving the immune mechanism	0.004	0.996	0.000
M79.1 Myalgia	0.000	0.996	0.004
F44 Dissociative [conversion] disorders	0.004	0.996	0.000
B25.9 Cytomegaloviral disease, unspecified	0.000	0.996	0.003
D09.7 Carcinoma in situ of other specified sites	0.003	0.996	0.000
D09.9 Carcinoma in situ, unspecified	0.003	0.997	0.000
D09.3 Thyroid and other endocrine glands	0.003	0.997	0.000
D09.2 Eye	0.003	0.997	0.000
F44.8 Other dissociative [conversion] disorders	0.003	0.997	0.000
I87.8 Other specified disorders of veins	0.003	0.997	0.000
D00.1 Oesophagus	0.003	0.997	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.003	0.997	0.000
D02.2 Bronchus and lung	0.003	0.997	0.000
M79.15 Myalgia (Pelvic region and thigh)	0.000	0.997	0.003
O00.1 Tubal pregnancy	0.000	0.997	0.003
D84 Other immunodeficiencies	0.003	0.997	0.000
D82 Immunodeficiency associated with other major defects	0.003	0.997	0.000
D00.2 Stomach	0.003	0.997	0.000
D02.4 Respiratory system, unspecified	0.003	0.997	0.000
D02.3 Other parts of respiratory system	0.003	0.997	0.000
D02.1 Trachea	0.003	0.997	0.000
I87.0 Postphlebitic syndrome	0.003	0.997	0.000
Z29.8 Other specified prophylactic measures	0.003	0.997	0.000
D01 Carcinoma in situ of other and unspecified digestive organs	0.003	0.997	0.000
M79.18 Myalgia (Other)	0.000	0.997	0.003
D09.1 Other and unspecified urinary organs	0.003	0.997	0.000
I87.9 Disorder of vein, unspecified	0.003	0.997	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.003	0.997	0.000
D82.1 Di George's syndrome	0.003	0.997	0.000
F44.5 Dissociative convulsions	0.003	0.997	0.000
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)	0.003	0.997	0.000
M85.08 Fibrous dysplasia (monostotic) (Other)	0.003	0.997	0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)	0.003	0.997	0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)	0.003	0.997	0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)	0.003	0.997	0.000
M85.04 Fibrous dysplasia (monostotic) (Hand)	0.003	0.997	0.000
M85.03 Fibrous dysplasia (monostotic) (Forearm)	0.003	0.997	0.000
M85.02 Fibrous dysplasia (monostotic) (Upper arm)	0.003	0.997	0.000
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)	0.003	0.997	0.000
Z76 Persons encountering health services in other circumstances	0.003	0.997	0.000
D84.8 Other specified immunodeficiencies	0.003	0.997	0.000
Y57.9 Drug or medicament, unspecified	0.003	0.997	0.000
D80 Immunodeficiency with predominantly antibody defects	0.003	0.997	0.000
Z70.1 Counselling related to patient's sexual behaviour and orientation	0.003	0.997	0.000
Z70.9 Sex counselling, unspecified	0.003	0.997	0.000
Z70.8 Other sex counselling	0.003	0.997	0.000
Z70.3 Counselling related to combined concerns regarding sexual attitude, behaviour and orientation	0.003	0.997	0.000
Z70.2 Counselling related to sexual behaviour and orientation of third party	0.003	0.997	0.000
Z70.0 Counselling related to sexual attitude	0.003	0.997	0.000
Y57.8 Other drugs and medicaments	0.003	0.997	0.000
D81 Combined immunodeficiencies	0.003	0.997	0.000
M79.17 Myalgia (Ankle and foot)	0.000	0.997	0.003
M79.14 Myalgia (Hand)	0.000	0.997	0.003
M79.13 Myalgia (Forearm)	0.000	0.997	0.003
M79.12 Myalgia (Upper arm)	0.000	0.997	0.003
F44.4 Dissociative motor disorders	0.003	0.997	0.000
F44.7 Mixed dissociative [conversion] disorders	0.003	0.997	0.000
F44.6 Dissociative anaesthesia and sensory loss	0.003	0.997	0.000
F44.3 Trance and possession disorders	0.003	0.997	0.000
F44.2 Dissociative stupor	0.003	0.997	0.000
F44.1 Dissociative fugue	0.003	0.997	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.003	0.997	0.000
E11.1 With ketoacidosis	0.003	0.997	0.000
G31.8 Other specified degenerative diseases of nervous system	0.003	0.997	0.000
D61 Other aplastic anaemias	0.000	0.997	0.003
F40 Phobic anxiety disorders	0.003	0.997	0.000
D84.9 Immunodeficiency, unspecified	0.003	0.997	0.000
M85 Other disorders of bone density and structure	0.003	0.997	0.000
D01.5 Liver, gallbladder and bile ducts	0.003	0.997	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.003	0.997	0.000
M85.4 Solitary bone cyst	0.003	0.997	0.000
R25.8 Other and unspecified abnormal involuntary movements	0.003	0.997	0.000
F40.2 Specific (isolated) phobias	0.003	0.997	0.000
M89.9 Disorder of bone, unspecified	0.003	0.997	0.000
D83 Common variable immunodeficiency	0.002	0.997	0.000
M79.11 Myalgia (Shoulder region)	0.000	0.997	0.002
D01.2 Rectum	0.002	0.997	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.002	0.997	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.002	0.997	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.002	0.997	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.002	0.997	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.002	0.997	0.000
D82.2 Immunodeficiency with short-limbed stature	0.002	0.997	0.000
D82.0 Wiskott-Aldrich syndrome	0.002	0.997	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.003	0.997	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.002	0.997	0.000
F44.0 Dissociative amnesia	0.002	0.997	0.000
M85.9 Disorder of bone density and structure, unspecified	0.003	0.997	0.000
D61.1 Drug-induced aplastic anaemia	0.000	0.997	0.002
F40.8 Other phobic anxiety disorders	0.002	0.997	0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.997	0.003
F40.9 Phobic anxiety disorder, unspecified	0.002	0.997	0.000
D01.9 Digestive organ, unspecified	0.002	0.997	0.000
D01.7 Other specified digestive organs	0.002	0.997	0.000
D01.4 Other and unspecified parts of intestine	0.002	0.997	0.000
D01.1 Rectosigmoid junction	0.002	0.997	0.000
D84.1 Defects in the complement system	0.002	0.997	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.002	0.997	0.000
M85.45 Solitary bone cyst (Pelvic region and thigh)	0.002	0.997	0.000
D06 Carcinoma in situ of cervix uteri	0.002	0.997	0.000
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)	0.002	0.998	0.000
D86.8 Sarcoidosis of other and combined sites	0.002	0.998	0.000
M85.8 Other specified disorders of bone density and structure	0.002	0.998	0.000
M85.47 Solitary bone cyst (Ankle and foot)	0.002	0.998	0.000
Z76.5 Malingerer [conscious situation]	0.002	0.998	0.000
Z76.4 Other boarder in health-care facility	0.002	0.998	0.000
Z76.2 Health supervision and care of other healthy infant and child	0.002	0.998	0.000
Z76.1 Health supervision and care of foundling	0.002	0.998	0.000
Z76.0 Issue of repeat prescription	0.002	0.998	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.002	0.998	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.002	0.998	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.002	0.998	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.002	0.998	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.002	0.998	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.002	0.998	0.000
G97.1 Other reaction to spinal and lumbar puncture	0.000	0.998	0.002
Q66.2 Metatarsus varus	0.000	0.998	0.002
D81.9 Combined immunodeficiency, unspecified	0.002	0.998	0.000
D81.8 Other combined immunodeficiencies	0.002	0.998	0.000
D81.7 Major histocompatibility complex class II deficiency	0.002	0.998	0.000
D81.6 Major histocompatibility complex class I deficiency	0.002	0.998	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.002	0.998	0.000
D81.4 Nezelof's syndrome	0.002	0.998	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.002	0.998	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.002	0.998	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.002	0.998	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.002	0.998	0.000
Z74 Problems related to care-provider dependency	0.002	0.998	0.000
D06.1 Exocervix	0.002	0.998	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.002	0.998	0.000
Z76.8 Persons encountering health services in other specified circumstances	0.002	0.998	0.000
D61.8 Other specified aplastic anaemias	0.000	0.998	0.002
D61.3 Idiopathic aplastic anaemia	0.000	0.998	0.002
D61.2 Aplastic anaemia due to other external agents	0.000	0.998	0.002
F40.1 Social phobias	0.002	0.998	0.000
Z71.3 Dietary counselling and surveillance	0.002	0.998	0.000
S72.20 Subtrochanteric fracture (closed)	0.000	0.998	0.002
D86 Sarcoidosis	0.002	0.998	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.002	0.998	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.002	0.998	0.000
M85.5 Aneurysmal bone cyst	0.002	0.998	0.000
M85.3 Osteitis condensans	0.002	0.998	0.000
M85.1 Skeletal fluorosis	0.002	0.998	0.000
M85.46 Solitary bone cyst (Lower leg)	0.002	0.998	0.000
L03.0 Cellulitis of finger and toe	0.000	0.998	0.002
M23.4 Loose body in knee	0.000	0.998	0.002
Y57 Other and unspecified drugs and medicaments	0.002	0.998	0.000
M85.49 Solitary bone cyst (Site unspecified)	0.002	0.998	0.000
M85.48 Solitary bone cyst (Other)	0.002	0.998	0.000
M85.44 Solitary bone cyst (Hand)	0.002	0.998	0.000
M85.43 Solitary bone cyst (Forearm)	0.002	0.998	0.000
M85.42 Solitary bone cyst (Upper arm)	0.002	0.998	0.000
M85.41 Solitary bone cyst (Shoulder region)	0.002	0.998	0.000
M85.40 Solitary bone cyst (Multiple sites)	0.002	0.998	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.002	0.998	0.000
D01.0 Colon	0.002	0.998	0.000
R35 Polyuria	0.002	0.998	0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.002	0.998	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.000	0.998	0.002
Z76.3 Healthy person accompanying sick person	0.002	0.998	0.000
D83.8 Other common variable immunodeficiencies	0.002	0.998	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.002	0.998	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.002	0.998	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.002	0.998	0.000
D86.3 Sarcoidosis of skin	0.002	0.998	0.000
G31.0 Circumscribed brain atrophy	0.002	0.998	0.000
M85.95 Disorder of bone density and structure, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M89.99 Disorder of bone, unspecified (Site unspecified)	0.002	0.998	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.002	0.998	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.000	0.998	0.002
M85.2 Hyperostosis of skull	0.002	0.998	0.000
Q66.7 Pes cavus	0.000	0.998	0.002
W25.9 Unspecified place	0.000	0.998	0.002
M89.98 Disorder of bone, unspecified (Other)	0.002	0.998	0.000
D01.3 Anus and anal canal	0.002	0.998	0.000
M85.98 Disorder of bone density and structure, unspecified (Other)	0.002	0.998	0.000
M85.97 Disorder of bone density and structure, unspecified (Ankle and foot)	0.002	0.998	0.000
M85.96 Disorder of bone density and structure, unspecified (Lower leg)	0.002	0.998	0.000
M85.94 Disorder of bone density and structure, unspecified (Hand)	0.002	0.998	0.000
M85.93 Disorder of bone density and structure, unspecified (Forearm)	0.002	0.998	0.000
M85.92 Disorder of bone density and structure, unspecified (Upper arm)	0.002	0.998	0.000
M85.91 Disorder of bone density and structure, unspecified (Shoulder region)	0.002	0.998	0.000
M85.90 Disorder of bone density and structure, unspecified (Multiple sites)	0.002	0.998	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.002	0.998	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.002	0.998	0.000
Q66.8 Other congenital deformities of feet	0.000	0.998	0.002
D07 Carcinoma in situ of other and unspecified genital organs	0.002	0.998	0.000
Z73 Problems related to life-management difficulty	0.002	0.998	0.000
Y40.8 Other systemic antibiotics	0.000	0.998	0.002
G81 Hemiplegia	0.000	0.998	0.002
M79.16 Myalgia (Lower leg)	0.000	0.998	0.002
M89.91 Disorder of bone, unspecified (Shoulder region)	0.002	0.998	0.000
D36.1 Peripheral nerves and autonomic nervous system	0.002	0.998	0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.002	0.998	0.000
M89.92 Disorder of bone, unspecified (Upper arm)	0.002	0.998	0.000
D06.7 Other parts of cervix	0.002	0.998	0.000
X50.4 Street and highway	0.000	0.998	0.002
Z88.2 Personal history of allergy to sulphonamides	0.000	0.998	0.002
R81 Glycosuria	0.002	0.998	0.000
M23.41 Loose body in knee-Ant lig/hrn men	0.000	0.998	0.002
G31.2 Degeneration of nervous system due to alcohol	0.002	0.998	0.000
F48 Other neurotic disorders	0.002	0.998	0.000
I73.9 Peripheral vascular disease, unspecified	0.002	0.998	0.000
Z74.1 Need for assistance with personal care	0.002	0.998	0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.002	0.998	0.000
M85.84 Other specified disorders of bone density and structure (Hand)	0.002	0.998	0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.002	0.998	0.000
B25 Cytomegaloviral disease	0.000	0.998	0.002
I34.1 Mitral (valve) prolapse	0.002	0.998	0.000
Q66 Congenital deformities of feet	0.000	0.998	0.002
D61.0 Constitutional aplastic anaemia	0.000	0.998	0.002
M23.40 Loose body in knee-Mult sites	0.000	0.998	0.002
D06.0 Endocervix	0.002	0.998	0.000
F45.0 Somatisation disorder	0.000	0.998	0.002
M81.4 Drug-induced osteoporosis	0.002	0.998	0.000
S51.9 Open wound of forearm, part unspecified	0.002	0.998	0.000
Y57.6 Other diagnostic agents	0.002	0.998	0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified	0.000	0.998	0.002
M85.83 Other specified disorders of bone density and structure (Forearm)	0.002	0.998	0.000
D07.3 Other and unspecified female genital organs	0.002	0.998	0.000
D07.0 Endometrium	0.002	0.998	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.002	0.998	0.000
D86.1 Sarcoidosis of lymph nodes	0.002	0.998	0.000
Z74.3 Need for continuous supervision	0.002	0.998	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
B34.9 Viral infection, unspecified	0.000	0.998	0.002
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.002	0.998	0.000
M85.6 Other cyst of bone	0.002	0.998	0.000
F43 Reaction to severe stress, and adjustment disorders	0.002	0.998	0.000
M85.19 Skeletal fluorosis (Site unspecified)	0.002	0.998	0.000
M85.18 Skeletal fluorosis (Other)	0.002	0.998	0.000
M85.17 Skeletal fluorosis (Ankle and foot)	0.002	0.998	0.000
M85.16 Skeletal fluorosis (Lower leg)	0.002	0.998	0.000
M85.15 Skeletal fluorosis (Pelvic region and thigh)	0.002	0.998	0.000
M85.14 Skeletal fluorosis (Hand)	0.002	0.998	0.000
M85.13 Skeletal fluorosis (Forearm)	0.002	0.998	0.000
M85.12 Skeletal fluorosis (Upper arm)	0.002	0.998	0.000
M85.11 Skeletal fluorosis (Shoulder region)	0.002	0.998	0.000
M85.10 Skeletal fluorosis (Multiple sites)	0.002	0.998	0.000
M85.39 Osteitis condensans (Site unspecified)	0.002	0.998	0.000
M85.38 Osteitis condensans (Other)	0.002	0.998	0.000
M85.37 Osteitis condensans (Ankle and foot)	0.002	0.998	0.000
M85.36 Osteitis condensans (Lower leg)	0.002	0.998	0.000
M85.35 Osteitis condensans (Pelvic region and thigh)	0.002	0.998	0.000
M85.34 Osteitis condensans (Hand)	0.002	0.998	0.000
M85.33 Osteitis condensans (Forearm)	0.002	0.998	0.000
M85.32 Osteitis condensans (Upper arm)	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations