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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74349534
log Bayes Factor = 15.5514
Chromosome 7   position 83,764,113  (GRCh37) Explore rs74349534 on Ensembl!
Variant rs74349534 is part of Cluster X0174

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
Chapter II Neoplasms
0.998 0.002 0.000
I30-I52 Other forms of heart disease
0.996 0.004 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.992 0.008 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.987 0.013 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.987 0.013 0.000
M20-M25 Other joint disorders
0.981 0.019 0.000
D10-D36 Benign neoplasms
0.981 0.019 0.000
I25.1 Atherosclerotic heart disease
0.980 0.020 0.000
E70-E90 Metabolic disorders
0.980 0.020 0.000
I50 Heart failure
0.975 0.025 0.000
D17 Benign lipomatous neoplasm
0.973 0.027 0.000
Z96 Presence of other functional implants
0.967 0.033 0.000
M50-M54 Other dorsopathies
0.966 0.034 0.000
M05-M14 Inflammatory polyarthropathies
0.964 0.036 0.000
I25.2 Old myocardial infarction
0.962 0.038 0.000
I21 Acute myocardial infarction
0.962 0.038 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.958 0.042 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.957 0.043 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.951 0.049 0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
0.950 0.050 0.000
Z96.1 Presence of intraocular lens
0.949 0.051 0.000
Z85 Personal history of malignant neoplasm
0.943 0.057 0.000
M54 Dorsalgia
0.942 0.058 0.000
D25 Leiomyoma of uterus
0.942 0.058 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.940 0.060 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.933 0.067 0.000
M70-M79 Other soft tissue disorders
0.930 0.070 0.000
E78.0 Pure hypercholesterolaemia
0.922 0.078 0.000
M23 Internal derangement of knee
0.920 0.080 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.910 0.090 0.000
D25.9 Leiomyoma of uterus, unspecified
0.909 0.091 0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.906 0.094 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.904 0.096 0.000
M54.2 Cervicalgia
0.900 0.100 0.000
I34 Nonrheumatic mitral valve disorders
0.900 0.100 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.897 0.103 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.891 0.109 0.000
M13 Other arthritis
0.890 0.110 0.000
Z94 Transplanted organ and tissue status
0.889 0.111 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.885 0.115 0.000
T81 Complications of procedures, not elsewhere classified
0.884 0.116 0.000
C50-C50 Malignant neoplasm of breast
0.883 0.117 0.000
E86 Volume depletion
0.882 0.118 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.881 0.119 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.880 0.120 0.000
E65-E68 Obesity and other hyperalimentation
0.877 0.123 0.000
I44 Atrioventricular and left bundle-branch block
0.876 0.124 0.000
I50.0 Congestive heart failure
0.874 0.126 0.000
I50.1 Left ventricular failure
0.873 0.127 0.000
M35 Other systemic involvement of connective tissue
0.871 0.129 0.000
M54.22 Cervicalgia (Cervical region)
0.869 0.131 0.000
M79.6 Pain in limb
0.867 0.133 0.000
I50.9 Heart failure, unspecified
0.862 0.137 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.861 0.139 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.860 0.140 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.859 0.141 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.851 0.149 0.000
M06 Other rheumatoid arthritis
0.848 0.152 0.000
M23.3 Other meniscus derangements
0.846 0.154 0.000
E20-E35 Disorders of other endocrine glands
0.845 0.155 0.000
Chapter VI Diseases of the nervous system
0.845 0.155 0.000
D27 Benign neoplasm of ovary
0.843 0.157 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.842 0.158 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.840 0.160 0.000
C15-C26 Malignant neoplasms of digestive organs
0.839 0.161 0.000
D00-D09 In situ neoplasms
0.838 0.162 0.000
M13.9 Arthritis, unspecified
0.837 0.163 0.000
I24 Other acute ischaemic heart diseases
0.833 0.167 0.000
E78.5 Hyperlipidaemia, unspecified
0.832 0.168 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.831 0.169 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.830 0.170 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.829 0.171 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.829 0.171 0.000
I34.0 Mitral (valve) insufficiency
0.828 0.172 0.000
Z95.0 Presence of cardiac pacemaker
0.824 0.176 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.823 0.177 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.822 0.178 0.000
I22 Subsequent myocardial infarction
0.822 0.178 0.000
M15-M19 Arthrosis
0.822 0.178 0.000
Z93 Artificial opening status
0.820 0.180 0.000
D45 Polycythaemia vera
0.818 0.182 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.817 0.183 0.000
L60-L75 Disorders of skin appendages
0.815 0.185 0.000
M25 Other joint disorders, not elsewhere classified
0.815 0.185 0.000
Z98 Other postsurgical states
0.815 0.185 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.814 0.186 0.000
I20 Angina pectoris
0.814 0.186 0.000
Chapter XX External causes of morbidity and mortality
0.810 0.190 0.000
M54.1 Radiculopathy
0.809 0.190 0.000
S60-S69 Injuries to the wrist and hand
0.806 0.194 0.000
Z96.7 Presence of other bone and tendon implants
0.806 0.194 0.000
I25.5 Ischaemic cardiomyopathy
0.805 0.195 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.805 0.195 0.000
T66-T78 Other and unspecified effects of external causes
0.803 0.197 0.000
M50 Cervical disk disorders
0.802 0.198 0.000
Z95.2 Presence of prosthetic heart valve
0.802 0.198 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.801 0.199 0.000
C50 Malignant neoplasm of breast
0.801 0.199 0.000
M79.62 Pain in limb (Upper arm)
0.797 0.203 0.000
M35.3 Polymyalgia rheumatica
0.796 0.204 0.000
D41.0 Kidney
0.795 0.205 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.795 0.205 0.000
E66 Obesity
0.794 0.206 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.793 0.207 0.000
Z94.8 Other transplanted organ and tissue status
0.790 0.210 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.790 0.210 0.000
Z97 Presence of other devices
0.789 0.211 0.000
D41.4 Bladder
0.788 0.212 0.000
I21.9 Acute myocardial infarction, unspecified
0.787 0.213 0.000
Z95.4 Presence of other heart-valve replacement
0.784 0.216 0.000
I33 Acute and subacute endocarditis
0.783 0.216 0.000
D70 Agranulocytosis
0.782 0.218 0.000
I46 Cardiac arrest
0.780 0.220 0.000
D34 Benign neoplasm of thyroid gland
0.780 0.220 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.778 0.222 0.000
Chapter VIII Diseases of the ear and mastoid process
0.778 0.222 0.000
Z85.4 Personal history of malignant neoplasm of genital organs
0.777 0.223 0.000
I45 Other conduction disorders
0.776 0.224 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.776 0.224 0.000
D25.0 Submucous leiomyoma of uterus
0.775 0.225 0.000
M54.9 Dorsalgia, unspecified
0.773 0.227 0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck
0.773 0.227 0.000
I47 Paroxysmal tachycardia
0.768 0.232 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.766 0.234 0.000
Z34 Supervision of normal pregnancy
0.765 0.235 0.000
M54.6 Pain in thoracic spine
0.765 0.235 0.000
I51 Complications and ill-defined descriptions of heart disease
0.764 0.235 0.000
O60-O75 Complications of labour and delivery
0.764 0.236 0.000
M86-M90 Other osteopathies
0.764 0.236 0.000
M19 Other arthrosis
0.761 0.239 0.000
D17.7 Benign lipomatous neoplasm of other sites
0.760 0.240 0.000
M80-M85 Disorders of bone density and structure
0.760 0.240 0.000
I05-I09 Chronic rheumatic heart diseases
0.760 0.240 0.000
Z30 Contraceptive management
0.759 0.241 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.758 0.242 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.757 0.243 0.000
M77 Other enthesopathies
0.757 0.243 0.000
Z95.1 Presence of aortocoronary bypass graft
0.757 0.243 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.752 0.248 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.752 0.248 0.000
I21.4 Acute subendocardial myocardial infarction
0.752 0.248 0.000
I60-I69 Cerebrovascular diseases
0.751 0.249 0.000
S90-S99 Injuries to the ankle and foot
0.750 0.250 0.000
M06.9 Rheumatoid arthritis, unspecified
0.749 0.251 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.748 0.252 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.746 0.254 0.000
M65-M68 Disorders of synovium and tendon
0.744 0.256 0.000
D17.9 Benign lipomatous neoplasm, unspecified
0.744 0.256 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.740 0.260 0.000
I71 Aortic aneurysm and dissection
0.740 0.260 0.000
Chapter XXII Codes for special purposes
0.740 0.260 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.739 0.261 0.000
I42 Cardiomyopathy
0.739 0.261 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.737 0.263 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.736 0.263 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.736 0.264 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.734 0.266 0.000
M07 Psoriatic and enteropathic arthropathies
0.734 0.266 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.734 0.266 0.000
M11 Other crystal arthropathies
0.732 0.268 0.000
I44.1 Atrioventricular block, second degree
0.732 0.268 0.000
D75 Other diseases of blood and blood-forming organs
0.732 0.268 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.730 0.270 0.000
M31 Other necrotising vasculopathies
0.730 0.270 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.729 0.271 0.000
I72 Other aneurysm
0.728 0.272 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.726 0.274 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.726 0.274 0.000
Z13 Special screening examination for other diseases and disorders
0.726 0.274 0.000
C50.9 Breast, unspecified
0.726 0.274 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.725 0.274 0.000
Z96.6 Presence of orthopaedic joint implants
0.724 0.276 0.000
M19.9 Arthrosis, unspecified
0.722 0.278 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.721 0.279 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.720 0.280 0.000
E83 Disorders of mineral metabolism
0.720 0.280 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Z89 Acquired absence of limb
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.3 Aneurysm of heart
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
D17.5 Benign lipomatous neoplasm of intra-abdominal organs
0.717 0.283 0.000
D46 Myelodysplastic syndromes
0.716 0.284 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.284 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.716 0.284 0.000
I52 Other heart disorders in diseases classified elsewhere
0.714 0.286 0.000
I48 Atrial fibrillation and flutter
0.714 0.286 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.714 0.286 0.000
I41 Myocarditis in diseases classified elsewhere
0.714 0.286 0.000
I40 Acute myocarditis
0.714 0.286 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.714 0.286 0.000
I37 Pulmonary valve disorders
0.714 0.286 0.000
I36 Nonrheumatic tricuspid valve disorders
0.714 0.286 0.000
I32 Pericarditis in diseases classified elsewhere
0.714 0.286 0.000
I30 Acute pericarditis
0.714 0.286 0.000
Z95.3 Presence of xenogenic heart valve
0.713 0.287 0.000
E40-E46 Malnutrition
0.711 0.288 0.000
Z83 Family history of other specific disorders
0.711 0.289 0.000
I44.6 Other and unspecified fascicular block
0.710 0.290 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.709 0.291 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.709 0.291 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.707 0.293 0.000
T79-T79 Certain early complications of trauma
0.707 0.293 0.000
M22 Disorders of patella
0.707 0.293 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.706 0.294 0.000
L72.1 Trichilemmal cyst
0.706 0.294 0.000
O00-O08 Pregnancy with abortive outcome
0.706 0.294 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.706 0.294 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.706 0.294 0.000
M21 Other acquired deformities of limbs
0.705 0.295 0.000
M20 Acquired deformities of fingers and toes
0.705 0.295 0.000
T78 Adverse effects, not elsewhere classified
0.705 0.295 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.703 0.297 0.000
M34 Systemic sclerosis
0.703 0.297 0.000
M33 Dermatopolymyositis
0.703 0.297 0.000
M32 Systemic lupus erythematosus
0.703 0.297 0.000
M30 Polyarteritis nodosa and related conditions
0.703 0.297 0.000
D32 Benign neoplasm of meninges
0.703 0.297 0.000
D31 Benign neoplasm of eye and adnexa
0.703 0.297 0.000
D30 Benign neoplasm of urinary organs
0.703 0.297 0.000
D29 Benign neoplasm of male genital organs
0.703 0.297 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.703 0.297 0.000
D26 Other benign neoplasms of uterus
0.703 0.297 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.703 0.297 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.703 0.297 0.000
D19 Benign neoplasm of mesothelial tissue
0.703 0.297 0.000
D16 Benign neoplasm of bone and articular cartilage
0.703 0.297 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.703 0.297 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.703 0.297 0.000
D10 Benign neoplasm of mouth and pharynx
0.703 0.297 0.000
E66.9 Obesity, unspecified
0.703 0.297 0.000
E88 Other metabolic disorders
0.702 0.298 0.000
E85 Amyloidosis
0.702 0.298 0.000
E84 Cystic fibrosis
0.702 0.298 0.000
E79 Disorders of purine and pyrimidine metabolism
0.702 0.298 0.000
E77 Disorders of glycoprotein metabolism
0.702 0.298 0.000
E76 Disorders of glycosaminoglycan metabolism
0.702 0.298 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.702 0.298 0.000
E74 Other disorders of carbohydrate metabolism
0.702 0.298 0.000
E73 Lactose intolerance
0.702 0.298 0.000
E72 Other disorders of amino-acid metabolism
0.702 0.298 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.702 0.298 0.000
E70 Disorders of aromatic amino-acid metabolism
0.702 0.298 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.702 0.298 0.000
S20-S29 Injuries to the thorax
0.702 0.298 0.000
Chapter VII Diseases of the eye and adnexa
0.702 0.298 0.000
M79.8 Other specified soft tissue disorders
0.701 0.299 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.701 0.299 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.701 0.299 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.700 0.300 0.000
C18 Malignant neoplasm of colon
0.699 0.301 0.000
I78 Diseases of capillaries
0.699 0.301 0.000
I44.0 Atrioventricular block, first degree
0.698 0.302 0.000
D17.4 Benign lipomatous neoplasm of intrathoracic organs
0.697 0.302 0.000
M45-M49 Spondylopathies
0.697 0.303 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.695 0.304 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.695 0.305 0.000
Z96.9 Presence of functional implant, unspecified
0.693 0.307 0.000
Z96.5 Presence of tooth-root and mandibular implants
0.693 0.307 0.000
Z96.4 Presence of endocrine implants
0.693 0.307 0.000
Z96.3 Presence of artificial larynx
0.693 0.307 0.000
Z96.2 Presence of otological and audiological implants
0.693 0.307 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.693 0.307 0.000
M53 Other dorsopathies, not elsewhere classified
0.693 0.307 0.000
Z30.2 Sterilisation
0.691 0.309 0.000
M14 Arthropathies in other diseases classified elsewhere
0.691 0.309 0.000
M12 Other specific arthropathies
0.691 0.309 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.691 0.309 0.000
M08 Juvenile arthritis
0.691 0.309 0.000
M05 Seropositive rheumatoid arthritis
0.691 0.309 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.690 0.310 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.690 0.310 0.000
Z85.6 Personal history of leukaemia
0.690 0.310 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.689 0.311 0.000
M24 Other specific joint derangements
0.689 0.311 0.000
Z94.0 Kidney transplant status
0.688 0.312 0.000
M25.4 Effusion of joint
0.687 0.313 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.687 0.313 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.687 0.313 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.687 0.313 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.687 0.313 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.687 0.313 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.687 0.313 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.687 0.313 0.000
Z93.2 Ileostomy status
0.687 0.313 0.000
S70-S79 Injuries to the hip and thigh
0.687 0.313 0.000
O23 Infections of genito-urinary tract in pregnancy
0.687 0.313 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.686 0.314 0.000
E78.8 Other disorders of lipoprotein metabolism
0.686 0.314 0.000
E78.6 Lipoprotein deficiency
0.686 0.314 0.000
E78.4 Other hyperlipidaemia
0.686 0.314 0.000
E78.3 Hyperchylomicronaemia
0.686 0.314 0.000
E78.2 Mixed hyperlipidaemia
0.686 0.314 0.000
E78.1 Pure hyperglyceridaemia
0.686 0.314 0.000
I44.7 Left bundle-branch block, unspecified
0.686 0.314 0.000
D25.2 Subserosal leiomyoma of uterus
0.685 0.315 0.000
E22 Hyperfunction of pituitary gland
0.685 0.315 0.000
G20-G26 Extrapyramidal and movement disorders
0.685 0.315 0.000
O20 Haemorrhage in early pregnancy
0.685 0.315 0.000
L40-L45 Papulosquamous disorders
0.684 0.316 0.000
Z35 Supervision of high-risk pregnancy
0.684 0.316 0.000
Z40 Prophylactic surgery
0.683 0.316 0.000
M79.64 Pain in limb (Hand)
0.683 0.317 0.000
I95 Hypotension
0.683 0.317 0.000
Z80 Family history of malignant neoplasm
0.683 0.317 0.000
Q60-Q64 Congenital malformations of the urinary system
0.682 0.318 0.000
L60 Nail disorders
0.682 0.318 0.000
O85-O92 Complications predominantly related to the puerperium
0.682 0.318 0.000
M79.67 Pain in limb (Ankle and foot)
0.681 0.319 0.000
Z12 Special screening examination for neoplasms
0.680 0.320 0.000
D80-D89 Certain disorders involving the immune mechanism
0.680 0.320 0.000
I51.7 Cardiomegaly
0.680 0.320 0.000
C50.4 Upper-outer quadrant of breast
0.679 0.321 0.000
M23.8 Other internal derangements of knee
0.679 0.321 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.678 0.322 0.000
E50-E64 Other nutritional deficiencies
0.678 0.322 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.676 0.324 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.676 0.324 0.000
M54.8 Other dorsalgia
0.676 0.324 0.000
M54.4 Lumbago with sciatica
0.676 0.324 0.000
M54.0 Panniculitis affecting regions of neck and back
0.676 0.324 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.675 0.325 0.000
T33-T35 Frostbite
0.674 0.326 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.674 0.326 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.674 0.326 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.674 0.326 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.674 0.326 0.000
T00-T07 Injuries involving multiple body regions
0.674 0.326 0.000
S10-S19 Injuries to the neck
0.674 0.326 0.000
Z39 Postpartum care and examination
0.674 0.326 0.000
D72 Other disorders of white blood cells
0.674 0.326 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.674 0.326 0.000
I20.9 Angina pectoris, unspecified
0.673 0.327 0.000
W20-W49 Exposure to inanimate mechanical forces
0.673 0.327 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.673 0.327 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.671 0.329 0.000
Z82.3 Family history of stroke
0.671 0.329 0.000
D11 Benign neoplasm of major salivary glands
0.670 0.330 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.670 0.330 0.000
Z98.8 Other specified postsurgical states
0.669 0.331 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.669 0.331 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.669 0.331 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.669 0.331 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.669 0.331 0.000
Z82.2 Family history of deafness and hearing loss
0.669 0.331 0.000
Z82.1 Family history of blindness and visual loss
0.669 0.331 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.669 0.331 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.668 0.332 0.000
Z34.9 Supervision of normal pregnancy, unspecified
0.668 0.332 0.000
M13.93 Arthritis, unspecified (Forearm)
0.667 0.333 0.000
M40-M43 Deforming dorsopathies
0.667 0.333 0.000
Z93.3 Colostomy status
0.667 0.333 0.000
M76 Enthesopathies of lower limb, excluding foot
0.666 0.333 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.666 0.333 0.000
M71 Other bursopathies
0.666 0.333 0.000
Z45 Adjustment and management of implanted device
0.664 0.336 0.000
M23.4 Loose body in knee
0.664 0.336 0.000
Z90.1 Acquired absence of breast(s)
0.663 0.337 0.000
D09 Carcinoma in situ of other and unspecified sites
0.662 0.338 0.000
L20-L30 Dermatitis and eczema
0.661 0.339 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.660 0.340 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.660 0.340 0.000
Z90.2 Acquired absence of lung [part of]
0.660 0.340 0.000
D60-D64 Aplastic and other anaemias
0.660 0.340 0.000
M54.17 Radiculopathy (Lumbosacral region)
0.660 0.340 0.000
M23.9 Internal derangement of knee, unspecified
0.660 0.340 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.660 0.340 0.000
M23.5 Chronic instability of knee
0.660 0.340 0.000
M23.1 Discoid meniscus (congenital)
0.660 0.340 0.000
M23.0 Cystic meniscus
0.660 0.340 0.000
C34 Malignant neoplasm of bronchus and lung
0.659 0.341 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.659 0.341 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.655 0.345 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.655 0.345 0.000
I34.1 Mitral (valve) prolapse
0.654 0.346 0.000
I24.8 Other forms of acute ischaemic heart disease
0.654 0.346 0.000
I47.2 Ventricular tachycardia
0.654 0.346 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.653 0.347 0.000
E10-E14 Diabetes mellitus
0.653 0.347 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.653 0.347 0.000
D55-D59 Haemolytic anaemias
0.652 0.348 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.652 0.348 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.652 0.348 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.652 0.348 0.000
D23 Other benign neoplasms of skin
0.652 0.348 0.000
E00-E07 Disorders of thyroid gland
0.652 0.348 0.000
S61 Open wound of wrist and hand
0.651 0.349 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.650 0.350 0.000
C20 Malignant neoplasm of rectum
0.649 0.351 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.649 0.351 0.000
I31 Other diseases of pericardium
0.649 0.351 0.000
H80-H83 Diseases of inner ear
0.649 0.351 0.000
T87 Complications peculiar to reattachment and amputation
0.648 0.352 0.000
T86 Failure and rejection of transplanted organs and tissues
0.648 0.352 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.648 0.352 0.000
M10 Gout
0.647 0.353 0.000
E66.8 Other obesity
0.646 0.354 0.000
M06.0 Seronegative rheumatoid arthritis
0.646 0.354 0.000
S62 Fracture at wrist and hand level
0.645 0.355 0.000
M54.29 Cervicalgia-Site unspe
0.645 0.355 0.000
M54.28 Cervicalgia-Sacral/sacrococ
0.645 0.355 0.000
M54.27 Cervicalgia-Lumbosacral
0.645 0.355 0.000
M54.26 Cervicalgia-Lumbar
0.645 0.355 0.000
M54.25 Cervicalgia-Thoracolumbar
0.645 0.355 0.000
M54.24 Cervicalgia-Thoracic
0.645 0.355 0.000
M54.23 Cervicalgia (Cervicothoracic region)
0.645 0.355 0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)
0.645 0.355 0.000
M54.20 Cervicalgia-Mult site
0.645 0.355 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.645 0.355 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.645 0.355 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.645 0.355 0.000
I70 Atherosclerosis
0.645 0.355 0.000
Z87 Personal history of other diseases and conditions
0.645 0.355 0.000
C16 Malignant neoplasm of stomach
0.643 0.357 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.643 0.357 0.000
I99 Other and unspecified disorders of circulatory system
0.643 0.357 0.000
D41.9 Urinary organ, unspecified
0.643 0.357 0.000
D41.7 Other urinary organs
0.643 0.357 0.000
D41.3 Urethra
0.643 0.357 0.000
D41.2 Ureter
0.643 0.357 0.000
D41.1 Renal pelvis
0.643 0.357 0.000
S80-S89 Injuries to the knee and lower leg
0.643 0.357 0.000
Q50-Q56 Congenital malformations of genital organs
0.640 0.360 0.000
M79.9 Soft tissue disorder, unspecified
0.639 0.361 0.000
M79.5 Residual foreign body in soft tissue
0.639 0.361 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.639 0.361 0.000
M79.3 Panniculitis, unspecified
0.639 0.361 0.000
M79.2 Neuralgia and neuritis, unspecified
0.639 0.361 0.000
M79.1 Myalgia
0.639 0.361 0.000
M13.8 Other specified arthritis
0.638 0.362 0.000
M13.1 Monoarthritis, not elsewhere classified
0.638 0.362 0.000
M13.0 Polyarthritis, unspecified
0.638 0.362 0.000
M54.64 Pain in thoracic spine (Thoracic region)
0.638 0.362 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.638 0.362 0.000
Z94.9 Transplanted organ and tissue status, unspecified
0.638 0.362 0.000
Z94.7 Corneal transplant status
0.638 0.362 0.000
Z94.6 Bone transplant status
0.638 0.362 0.000
Z94.5 Skin transplant status
0.638 0.362 0.000
Z94.4 Liver transplant status
0.638 0.362 0.000
Z94.3 Heart and lungs transplant status
0.638 0.362 0.000
Z94.2 Lung transplant status
0.638 0.362 0.000
Z94.1 Heart transplant status
0.638 0.362 0.000
Z49 Care involving dialysis
0.637 0.363 0.000
M50.1 Cervical disk disorder with radiculopathy
0.636 0.364 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.636 0.364 0.000
Z97.5 Presence of (intra-uterine) contraceptive device
0.635 0.365 0.000
C64-C68 Malignant neoplasms of urinary tract
0.634 0.366 0.000
T81.9 Unspecified complication of procedure
0.633 0.366 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.633 0.366 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.633 0.366 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.633 0.366 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.633 0.366 0.000
M79.66 Pain in limb (Lower leg)
0.633 0.367 0.000
I38 Endocarditis, valve unspecified
0.632 0.368 0.000
E27 Other disorders of adrenal gland
0.632 0.368 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.632 0.368 0.000
L10-L14 Bullous disorders
0.632 0.368 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.631 0.368 0.000
D06 Carcinoma in situ of cervix uteri
0.631 0.369 0.000
G90-G99 Other disorders of the nervous system
0.631 0.369 0.000
Z38 Liveborn infants according to place of birth
0.631 0.369 0.000
Z32 Pregnancy examination and test
0.631 0.369 0.000
Z31 Procreative management
0.631 0.369 0.000
M54.12 Radiculopathy (Cervical region)
0.631 0.369 0.000
I33.0 Acute and subacute infective endocarditis
0.631 0.369 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.630 0.370 0.000
M50.3 Other cervical disk degeneration
0.630 0.370 0.000
S40-S49 Injuries to the shoulder and upper arm
0.630 0.370 0.000
E67 Other hyperalimentation
0.628 0.371 0.000
E68 Sequelae of hyperalimentation
0.628 0.371 0.000
E65 Localised adiposity
0.628 0.371 0.000
I44.5 Left posterior fascicular block
0.628 0.372 0.000
I44.4 Left anterior fascicular block
0.628 0.372 0.000
I44.3 Other and unspecified atrioventricular block
0.628 0.372 0.000
I45.5 Other specified heart block
0.627 0.373 0.000
Z98.2 Presence of cerebrospinal fluid drainage device
0.627 0.373 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.626 0.374 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.625 0.375 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.624 0.376 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.624 0.376 0.000
M35.8 Other specified systemic involvement of connective tissue
0.624 0.376 0.000
M35.7 Hypermobility syndrome
0.624 0.376 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.624 0.376 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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