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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74385618
log Bayes Factor = 11.915
Chromosome 5   position 62,522,666  (GRCh37) Explore rs74385618 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter II Neoplasms
0.998 0.002 0.000
Chapter XX External causes of morbidity and mortality
0.996 0.004 0.000
Chapter XXI Factors influencing health status and contact with health services
0.995 0.005 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.993 0.007 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.992 0.008 0.000
Chapter I Certain infectious and parasitic diseases
0.992 0.008 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.991 0.009 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.986 0.014 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.983 0.017 0.000
I30-I52 Other forms of heart disease
0.978 0.022 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.974 0.026 0.000
Z90.7 Acquired absence of genital organ(s)
0.974 0.026 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.966 0.034 0.000
I20-I25 Ischaemic heart diseases
0.965 0.035 0.000
Chapter VI Diseases of the nervous system
0.963 0.037 0.000
C15-C26 Malignant neoplasms of digestive organs
0.960 0.040 0.000
Chapter X Diseases of the respiratory system
0.959 0.041 0.000
I05-I09 Chronic rheumatic heart diseases
0.956 0.044 0.000
I25 Chronic ischaemic heart disease
0.955 0.045 0.000
C34 Malignant neoplasm of bronchus and lung
0.955 0.045 0.000
J09-J18 Influenza and pneumonia
0.948 0.052 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.944 0.056 0.000
I51 Complications and ill-defined descriptions of heart disease
0.940 0.060 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.939 0.061 0.000
C34.9 Bronchus or lung, unspecified
0.936 0.064 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.935 0.065 0.000
I25.2 Old myocardial infarction
0.933 0.067 0.000
I60-I69 Cerebrovascular diseases
0.933 0.067 0.000
J18 Pneumonia, organism unspecified
0.933 0.067 0.000
C91 Lymphoid leukaemia
0.932 0.068 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.931 0.069 0.000
A30-A49 Other bacterial diseases
0.927 0.073 0.000
Z95.0 Presence of cardiac pacemaker
0.927 0.073 0.000
Z90.1 Acquired absence of breast(s)
0.926 0.074 0.000
C20 Malignant neoplasm of rectum
0.926 0.074 0.000
B35-B49 Mycoses
0.926 0.074 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.924 0.076 0.000
Z95.1 Presence of aortocoronary bypass graft
0.922 0.078 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.921 0.079 0.000
J90-J94 Other diseases of pleura
0.918 0.082 0.000
Z96 Presence of other functional implants
0.917 0.083 0.000
Z51 Other medical care
0.916 0.084 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.915 0.085 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.910 0.090 0.000
J18.9 Pneumonia, unspecified
0.909 0.091 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.909 0.091 0.000
M50-M54 Other dorsopathies
0.909 0.091 0.000
S40-S49 Injuries to the shoulder and upper arm
0.907 0.093 0.000
Z95.4 Presence of other heart-valve replacement
0.905 0.095 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.899 0.101 0.000
I44 Atrioventricular and left bundle-branch block
0.888 0.112 0.000
Z90.2 Acquired absence of lung [part of]
0.887 0.113 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.886 0.114 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.885 0.115 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.884 0.116 0.000
I69 Sequelae of cerebrovascular disease
0.883 0.117 0.000
C91.1 Chronic lymphocytic leukaemia
0.883 0.117 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.883 0.117 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.882 0.118 0.000
Z89 Acquired absence of limb
0.882 0.118 0.000
I51.7 Cardiomegaly
0.882 0.118 0.000
M50 Cervical disk disorders
0.880 0.120 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.879 0.121 0.000
C83.3 Large cell (diffuse)
0.878 0.122 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.876 0.124 0.000
A49 Bacterial infection of unspecified site
0.875 0.125 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.874 0.126 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.873 0.127 0.000
B07 Viral warts
0.873 0.127 0.000
Chapter XXII Codes for special purposes
0.870 0.130 0.000
I08 Multiple valve diseases
0.869 0.131 0.000
I50 Heart failure
0.868 0.132 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.867 0.133 0.000
I05 Rheumatic mitral valve diseases
0.859 0.141 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.857 0.143 0.000
N20-N23 Urolithiasis
0.856 0.144 0.000
Chapter XIV Diseases of the genitourinary system
0.856 0.144 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.854 0.146 0.000
O80-O84 Delivery
0.851 0.149 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.849 0.151 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.844 0.156 0.000
G30-G32 Other degenerative diseases of the nervous system
0.841 0.159 0.000
J18.1 Lobar pneumonia, unspecified
0.839 0.161 0.000
Z96.0 Presence of urogenital implants
0.839 0.161 0.000
N23 Unspecified renal colic
0.836 0.164 0.000
Chapter VII Diseases of the eye and adnexa
0.835 0.165 0.000
N20 Calculus of kidney and ureter
0.834 0.166 0.000
I51.8 Other ill-defined heart diseases
0.834 0.166 0.000
O80 Single spontaneous delivery
0.833 0.167 0.000
Y85 Sequelae of transport accidents
0.830 0.170 0.000
S90-S99 Injuries to the ankle and foot
0.829 0.171 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.829 0.171 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.828 0.172 0.000
C79 Secondary malignant neoplasm of other sites
0.826 0.174 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.825 0.175 0.000
M45-M49 Spondylopathies
0.824 0.176 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.824 0.176 0.000
J90 Pleural effusion, not elsewhere classified
0.824 0.176 0.000
D60-D64 Aplastic and other anaemias
0.823 0.177 0.000
T79-T79 Certain early complications of trauma
0.822 0.178 0.000
X60-X84 Intentional self-harm
0.821 0.179 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.820 0.180 0.000
I44.0 Atrioventricular block, first degree
0.819 0.181 0.000
M40-M43 Deforming dorsopathies
0.819 0.181 0.000
Y44 Agents primarily affecting blood constituents
0.819 0.181 0.000
I22 Subsequent myocardial infarction
0.818 0.182 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.817 0.183 0.000
S50-S59 Injuries to the elbow and forearm
0.817 0.183 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.816 0.184 0.000
Z51.0 Radiotherapy session
0.814 0.186 0.000
I31 Other diseases of pericardium
0.812 0.188 0.000
A49.9 Bacterial infection, unspecified
0.812 0.188 0.000
D73 Diseases of spleen
0.810 0.190 0.000
Z96.8 Presence of other specified functional implants
0.808 0.192 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.808 0.192 0.000
I35 Nonrheumatic aortic valve disorders
0.806 0.194 0.000
B35 Dermatophytosis
0.805 0.195 0.000
S20-S29 Injuries to the thorax
0.804 0.196 0.000
C34.3 Lower lobe, bronchus or lung
0.800 0.199 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.800 0.200 0.000
H40-H42 Glaucoma
0.800 0.200 0.000
J92 Pleural plaque
0.799 0.201 0.000
G90-G99 Other disorders of the nervous system
0.797 0.203 0.000
C16 Malignant neoplasm of stomach
0.796 0.204 0.000
C17 Malignant neoplasm of small intestine
0.794 0.206 0.000
Z49 Care involving dialysis
0.793 0.207 0.000
Z51.5 Palliative care
0.793 0.207 0.000
W20-W49 Exposure to inanimate mechanical forces
0.791 0.209 0.000
Z54 Convalescence
0.787 0.213 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.787 0.213 0.000
C25 Malignant neoplasm of pancreas
0.787 0.213 0.000
Z96.1 Presence of intraocular lens
0.786 0.214 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.785 0.215 0.000
V20-V29 Motorcycle rider injured in transport accident
0.784 0.216 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.783 0.217 0.000
A40 Streptococcal septicaemia
0.782 0.218 0.000
W50-W64 Exposure to animate mechanical forces
0.781 0.219 0.000
B50-B64 Protozoal diseases
0.780 0.220 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.779 0.221 0.000
C21 Malignant neoplasm of anus and anal canal
0.778 0.222 0.000
O80.0 Spontaneous vertex delivery
0.777 0.223 0.000
B15-B19 Viral hepatitis
0.777 0.223 0.000
O80.9 Single spontaneous delivery, unspecified
0.776 0.224 0.000
Z97 Presence of other devices
0.776 0.224 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.775 0.225 0.000
Z99.8 Dependence on other enabling machines and devices
0.775 0.225 0.000
H40 Glaucoma
0.774 0.226 0.000
J60-J70 Lung diseases due to external agents
0.774 0.226 0.000
I71 Aortic aneurysm and dissection
0.769 0.231 0.000
J91 Pleural effusion in conditions classified elsewhere
0.768 0.232 0.000
E50-E64 Other nutritional deficiencies
0.768 0.232 0.000
N20.0 Calculus of kidney
0.768 0.232 0.000
C92 Myeloid leukaemia
0.767 0.233 0.000
I69.3 Sequelae of cerebral infarction
0.766 0.234 0.000
S43.0 Dislocation of shoulder joint
0.765 0.235 0.000
M50.2 Other cervical disk displacement
0.761 0.239 0.000
Z51.1 Chemotherapy session for neoplasm
0.761 0.239 0.000
Z41 Procedures for purposes other than remedying health state
0.759 0.241 0.000
Z95.2 Presence of prosthetic heart valve
0.759 0.241 0.000
I44.3 Other and unspecified atrioventricular block
0.758 0.242 0.000
D73.0 Hyposplenism
0.757 0.243 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.757 0.243 0.000
I61 Intracerebral haemorrhage
0.757 0.243 0.000
M50.3 Other cervical disk degeneration
0.755 0.245 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.755 0.245 0.000
M45 Ankylosing spondylitis
0.753 0.247 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.752 0.248 0.000
I36 Nonrheumatic tricuspid valve disorders
0.752 0.248 0.000
M60-M63 Disorders of muscles
0.752 0.248 0.000
O16 Unspecified maternal hypertension
0.751 0.249 0.000
Z47 Other orthopaedic follow-up care
0.751 0.249 0.000
J95-J99 Other diseases of the respiratory system
0.749 0.251 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.749 0.251 0.000
G35 Multiple sclerosis
0.749 0.251 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.747 0.253 0.000
N20.1 Calculus of ureter
0.747 0.253 0.000
Y85.0 Sequelae of motor-vehicle accident
0.747 0.253 0.000
I50.1 Left ventricular failure
0.747 0.253 0.000
B44 Aspergillosis
0.746 0.254 0.000
Z48 Other surgical follow-up care
0.745 0.255 0.000
I30 Acute pericarditis
0.745 0.255 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.744 0.256 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.743 0.257 0.000
D64 Other anaemias
0.743 0.257 0.000
G30 Alzheimer's disease
0.742 0.258 0.000
M50.1 Cervical disk disorder with radiculopathy
0.741 0.259 0.000
I26 Pulmonary embolism
0.740 0.260 0.000
D75 Other diseases of blood and blood-forming organs
0.740 0.260 0.000
Z89.6 Acquired absence of leg above knee
0.740 0.260 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.740 0.260 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.740 0.260 0.000
T92 Sequelae of injuries of upper limb
0.739 0.260 0.000
Y44.2 Anticoagulants
0.738 0.262 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.737 0.263 0.000
B49 Unspecified mycosis
0.736 0.264 0.000
S10-S19 Injuries to the neck
0.735 0.265 0.000
J17 Pneumonia in diseases classified elsewhere
0.735 0.265 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.735 0.265 0.000
I60 Subarachnoid haemorrhage
0.734 0.266 0.000
G40-G47 Episodic and paroxysmal disorders
0.734 0.266 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.733 0.267 0.000
A48 Other bacterial diseases, not elsewhere classified
0.733 0.267 0.000
M91-M94 Chondropathies
0.732 0.268 0.000
N00-N08 Glomerular diseases
0.731 0.269 0.000
G90 Disorders of autonomic nervous system
0.731 0.269 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.731 0.269 0.000
M80-M85 Disorders of bone density and structure
0.731 0.269 0.000
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]
0.731 0.269 0.000
Y86 Sequelae of other accidents
0.730 0.270 0.000
I35.1 Aortic (valve) insufficiency
0.730 0.270 0.000
C64-C68 Malignant neoplasms of urinary tract
0.729 0.271 0.000
M86-M90 Other osteopathies
0.729 0.271 0.000
N10-N16 Renal tubulo-interstitial diseases
0.729 0.271 0.000
S42 Fracture of shoulder and upper arm
0.728 0.272 0.000
C32 Malignant neoplasm of larynx
0.728 0.272 0.000
V80-V89 Other land transport accidents
0.728 0.272 0.000
Y45.0 Opioids and related analgesics
0.727 0.273 0.000
C91.0 Acute lymphoblastic leukaemia
0.725 0.275 0.000
B02 Zoster [herpes zoster]
0.725 0.275 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.724 0.276 0.000
I67 Other cerebrovascular diseases
0.724 0.276 0.000
I51.6 Cardiovascular disease, unspecified
0.723 0.277 0.000
M50.0 Cervical disk disorder with myelopathy
0.723 0.277 0.000
B00 Herpesviral [herpes simplex] infections
0.722 0.278 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.722 0.278 0.000
J92.9 Pleural plaque without asbestos
0.720 0.280 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.719 0.280 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.719 0.281 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.719 0.281 0.000
N99-N99 Other disorders of the genitourinary system
0.719 0.281 0.000
T66-T78 Other and unspecified effects of external causes
0.718 0.282 0.000
V10-V19 Pedal cyclist injured in transport accident
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
D66 Hereditary factor VIII deficiency
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
B37 Candidiasis
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
A80-A89 Viral infections of the central nervous system
0.716 0.284 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.716 0.284 0.000
H10-H13 Disorders of conjunctiva
0.716 0.284 0.000
M54 Dorsalgia
0.716 0.284 0.000
I05.0 Mitral stenosis
0.716 0.284 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
E00-E07 Disorders of thyroid gland
0.716 0.284 0.000
A49.1 Streptococcal infection, unspecified
0.715 0.284 0.000
S41 Open wound of shoulder and upper arm
0.715 0.285 0.000
I74 Arterial embolism and thrombosis
0.715 0.285 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.714 0.286 0.000
Y35-Y36 Legal intervention and operations of war
0.714 0.286 0.000
Y10-Y34 Event of undetermined intent
0.714 0.286 0.000
Y00-Y09 Assault
0.714 0.286 0.000
X85-X99 Assault
0.714 0.286 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.714 0.286 0.000
X50-X57 Overexertion, travel and privation
0.714 0.286 0.000
X30-X39 Exposure to forces of nature
0.714 0.286 0.000
X20-X29 Contact with venomous animals and plants
0.714 0.286 0.000
X10-X19 Contact with heat and hot substances
0.714 0.286 0.000
X00-X09 Exposure to smoke, fire and flames
0.714 0.286 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.714 0.286 0.000
W75-W84 Other accidental threats to breathing
0.714 0.286 0.000
W65-W74 Accidental drowning and submersion
0.714 0.286 0.000
V98-V99 Other and unspecified transport accidents
0.714 0.286 0.000
V95-V97 Air and space transport accidents
0.714 0.286 0.000
V90-V94 Water transport accidents
0.714 0.286 0.000
V70-V79 Bus occupant injured in transport accident
0.714 0.286 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.714 0.286 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.714 0.286 0.000
V40-V49 Car occupant injured in transport accident
0.714 0.286 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.714 0.286 0.000
V01-V09 Pedestrian injured in transport accident
0.714 0.286 0.000
Z81 Family history of mental and behavioural disorders
0.713 0.287 0.000
Z84 Family history of other conditions
0.712 0.288 0.000
B99-B99 Other infectious diseases
0.711 0.289 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.711 0.289 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.711 0.289 0.000
B65-B83 Helminthiases
0.711 0.289 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.711 0.289 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.711 0.289 0.000
A75-A79 Rickettsioses
0.711 0.289 0.000
A70-A74 Other diseases caused by chlamydiae
0.711 0.289 0.000
A65-A69 Other spirochaetal diseases
0.711 0.289 0.000
A20-A28 Certain zoonotic bacterial diseases
0.711 0.289 0.000
A15-A19 Tuberculosis
0.711 0.289 0.000
Z99.3 Dependence on wheelchair
0.711 0.289 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.711 0.289 0.000
I77 Other disorders of arteries and arterioles
0.711 0.289 0.000
C25.9 Pancreas, unspecified
0.709 0.291 0.000
I44.6 Other and unspecified fascicular block
0.708 0.292 0.000
I08.0 Disorders of both mitral and aortic valves
0.708 0.292 0.000
A00-A09 Intestinal infectious diseases
0.707 0.293 0.000
I27 Other pulmonary heart diseases
0.707 0.293 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.707 0.293 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.707 0.293 0.000
C95 Leukaemia of unspecified cell type
0.707 0.293 0.000
C94 Other leukaemias of specified cell type
0.707 0.293 0.000
C93 Monocytic leukaemia
0.707 0.293 0.000
C88 Malignant immunoproliferative diseases
0.707 0.293 0.000
C86 Other specified types of T/NK-cell lymphoma
0.707 0.293 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.707 0.293 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.707 0.293 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.706 0.293 0.000
I72 Other aneurysm
0.706 0.294 0.000
E10-E14 Diabetes mellitus
0.706 0.294 0.000
T86 Failure and rejection of transplanted organs and tissues
0.705 0.295 0.000
M43 Other deforming dorsopathies
0.705 0.295 0.000
T33-T35 Frostbite
0.705 0.295 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.705 0.295 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.705 0.295 0.000
T00-T07 Injuries involving multiple body regions
0.705 0.295 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.705 0.295 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.704 0.296 0.000
I34 Nonrheumatic mitral valve disorders
0.703 0.297 0.000
Z90.3 Acquired absence of part of stomach
0.702 0.298 0.000
Q80-Q89 Other congenital malformations
0.701 0.299 0.000
I52 Other heart disorders in diseases classified elsewhere
0.701 0.299 0.000
I48 Atrial fibrillation and flutter
0.701 0.299 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.701 0.299 0.000
I41 Myocarditis in diseases classified elsewhere
0.701 0.299 0.000
I40 Acute myocarditis
0.701 0.299 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.701 0.299 0.000
I32 Pericarditis in diseases classified elsewhere
0.701 0.299 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.701 0.299 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.700 0.300 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.698 0.301 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.698 0.301 0.000
C31 Malignant neoplasm of accessory sinuses
0.698 0.301 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.698 0.301 0.000
C37 Malignant neoplasm of thymus
0.698 0.301 0.000
C33 Malignant neoplasm of trachea
0.698 0.301 0.000
U80 Agent resistant to penicillin and related antibiotics
0.698 0.302 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.696 0.304 0.000
M65-M68 Disorders of synovium and tendon
0.696 0.304 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.695 0.305 0.000
D69 Purpura and other haemorrhagic conditions
0.694 0.306 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.694 0.306 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.693 0.307 0.000
Z63 Other problems related to primary support group, including family circumstances
0.693 0.307 0.000
E55 Vitamin D deficiency
0.693 0.307 0.000
Y65 Other misadventures during surgical and medical care
0.693 0.307 0.000
D55-D59 Haemolytic anaemias
0.692 0.308 0.000
I23 Certain current complications following acute myocardial infarction
0.692 0.308 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.691 0.309 0.000
C34.0 Main bronchus
0.691 0.309 0.000
Z96.2 Presence of otological and audiological implants
0.690 0.310 0.000
T90 Sequelae of injuries of head
0.689 0.311 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.688 0.312 0.000
C23 Malignant neoplasm of gallbladder
0.688 0.312 0.000
N20.2 Calculus of kidney with calculus of ureter
0.688 0.312 0.000
Z52 Donors of organs and tissues
0.686 0.314 0.000
I09 Other rheumatic heart diseases
0.685 0.315 0.000
I06 Rheumatic aortic valve diseases
0.685 0.315 0.000
D64.9 Anaemia, unspecified
0.685 0.315 0.000
I25.6 Silent myocardial ischaemia
0.685 0.315 0.000
I25.4 Coronary artery aneurysm
0.685 0.315 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.685 0.315 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.685 0.315 0.000
C34.8 Overlapping lesion of bronchus and lung
0.685 0.315 0.000
C34.2 Middle lobe, bronchus or lung
0.685 0.315 0.000
G82 Paraplegia and tetraplegia
0.685 0.315 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.684 0.316 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.683 0.317 0.000
M00-M03 Infectious arthropathies
0.683 0.317 0.000
B35.1 Tinea unguium
0.683 0.317 0.000
Z54.0 Convalescence following surgery
0.682 0.318 0.000
Y57 Other and unspecified drugs and medicaments
0.682 0.318 0.000
I07 Rheumatic tricuspid valve diseases
0.681 0.318 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.680 0.320 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.680 0.320 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.680 0.320 0.000
J12 Viral pneumonia, not elsewhere classified
0.680 0.320 0.000
J14 Pneumonia due to Haemophilus influenzae
0.680 0.320 0.000
J09 Influenza due to certain identified influenza virus
0.680 0.320 0.000
T91 Sequelae of injuries of neck and trunk
0.677 0.323 0.000
Q50-Q56 Congenital malformations of genital organs
0.677 0.323 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.677 0.323 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.677 0.323 0.000
Z98 Other postsurgical states
0.676 0.324 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.676 0.324 0.000
Z43 Attention to artificial openings
0.676 0.324 0.000
W22 Striking against or struck by other objects
0.676 0.324 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.675 0.325 0.000
C83.0 Small cell (diffuse)
0.675 0.325 0.000
I51.5 Myocardial degeneration
0.674 0.326 0.000
I51.4 Myocarditis, unspecified
0.674 0.326 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.674 0.326 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.674 0.326 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.674 0.326 0.000
I51.0 Cardiac septal defect, acquired
0.674 0.326 0.000
I24 Other acute ischaemic heart diseases
0.674 0.326 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.674 0.326 0.000
I50.9 Heart failure, unspecified
0.674 0.326 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.674 0.326 0.000
J93 Pneumothorax
0.674 0.326 0.000
C80 Malignant neoplasm without specification of site
0.673 0.327 0.000
I62 Other nontraumatic intracranial haemorrhage
0.673 0.327 0.000
B06 Rubella [German measles]
0.673 0.327 0.000
B05 Measles
0.673 0.327 0.000
B01 Varicella [chickenpox]
0.673 0.327 0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions
0.673 0.327 0.000
B04 Monkeypox
0.673 0.327 0.000
B03 Smallpox
0.673 0.327 0.000
O85-O92 Complications predominantly related to the puerperium
0.672 0.327 0.000
I05.1 Rheumatic mitral insufficiency
0.672 0.328 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.672 0.328 0.000
Y40 Systemic antibiotics
0.671 0.329 0.000
D50-D53 Nutritional anaemias
0.671 0.329 0.000
G30.9 Alzheimer's disease, unspecified
0.671 0.329 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.670 0.330 0.000
Z44 Fitting and adjustment of external prosthetic device
0.670 0.330 0.000
J10 Influenza due to identified influenza virus
0.670 0.330 0.000
Z94 Transplanted organ and tissue status
0.670 0.330 0.000
Y88 Sequelae of surgical and medical care as external cause
0.669 0.331 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.669 0.331 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.669 0.331 0.000
J18.8 Other pneumonia, organism unspecified
0.669 0.331 0.000
J18.2 Hypostatic pneumonia, unspecified
0.669 0.331 0.000
I50.0 Congestive heart failure
0.668 0.332 0.000
C91.9 Lymphoid leukaemia, unspecified
0.668 0.332 0.000
C91.8 Mature B-cell leukaemia Burkitt-type
0.668 0.332 0.000
C91.7 Other lymphoid leukaemia
0.668 0.332 0.000
C91.6 Prolymphocytic leukaemia of T-cell type
0.668 0.332 0.000
C91.5 Adult T-cell leukaemia
0.668 0.332 0.000
C91.4 Hairy-cell leukaemia
0.668 0.332 0.000
C91.3 Prolymphocytic leukaemia
0.668 0.332 0.000
C91.2 Subacute lymphocytic leukaemia
0.668 0.332 0.000
I44.2 Atrioventricular block, complete
0.668 0.332 0.000
G44 Other headache syndromes
0.668 0.332 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.668 0.332 0.000
Y59 Other and unspecified vaccines and biological substances
0.667 0.332 0.000
Y58 Bacterial vaccines
0.667 0.332 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.667 0.332 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.667 0.332 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.667 0.332 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.667 0.332 0.000
Y48 Anaesthetics and therapeutic gases
0.667 0.332 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.667 0.332 0.000
H55-H59 Other disorders of eye and adnexa
0.667 0.333 0.000
C45 Mesothelioma
0.666 0.334 0.000
I05.9 Mitral valve disease, unspecified
0.666 0.334 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.666 0.334 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.666 0.334 0.000
I05.2 Mitral stenosis with insufficiency
0.665 0.335 0.000
A44 Bartonellosis
0.665 0.335 0.000
A43 Nocardiosis
0.665 0.335 0.000
A42 Actinomycosis
0.665 0.335 0.000
A39 Meningococcal infection
0.665 0.335 0.000
A37 Whooping cough
0.665 0.335 0.000
A36 Diphtheria
0.665 0.335 0.000
A32 Listeriosis
0.665 0.335 0.000
A31 Infection due to other mycobacteria
0.665 0.335 0.000
A30 Leprosy [Hansen's disease]
0.665 0.335 0.000
A46 Erysipelas
0.665 0.335 0.000
A38 Scarlet fever
0.665 0.335 0.000
A35 Other tetanus
0.665 0.335 0.000
A34 Obstetrical tetanus
0.665 0.335 0.000
A33 Tetanus neonatorum
0.665 0.335 0.000
H40.2 Primary angle-closure glaucoma
0.664 0.336 0.000
B48 Other mycoses, not elsewhere classified
0.664 0.336 0.000
B47 Mycetoma
0.664 0.336 0.000
B46 Zygomycosis
0.664 0.336 0.000
B45 Cryptococcosis
0.664 0.336 0.000
B43 Chromomycosis and phaeomycotic abscess
0.664 0.336 0.000
B42 Sporotrichosis
0.664 0.336 0.000
B41 Paracoccidioidomycosis
0.664 0.336 0.000
B40 Blastomycosis
0.664 0.336 0.000
B39 Histoplasmosis
0.664 0.336 0.000
B38 Coccidioidomycosis
0.664 0.336 0.000
B36 Other superficial mycoses
0.664 0.336 0.000
C60-C63 Malignant neoplasms of male genital organs
0.664 0.336 0.000
W00-W19 Falls
0.663 0.337 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.663 0.337 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.663 0.337 0.000
C83.7 Burkitt's tumour
0.663 0.337 0.000
C83.6 Undifferentiated (diffuse)
0.663 0.337 0.000
C83.5 Lymphoblastic (diffuse)
0.663 0.337 0.000
C83.4 Immunoblastic (diffuse)
0.663 0.337 0.000
C83.2 Mixed small and large cell (diffuse)
0.663 0.337 0.000
C83.1 Small cleaved cell (diffuse)
0.663 0.337 0.000
I35.9 Aortic valve disorder, unspecified
0.662 0.338 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.661 0.339 0.000
J11 Influenza, virus not identified
0.660 0.339 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.660 0.340 0.000
I31.3 Pericardial effusion (noninflammatory)
0.660 0.340 0.000
S27 Injury of other and unspecified intrathoracic organs
0.660 0.340 0.000
Z97.8 Presence of other specified devices
0.659 0.341 0.000
Z89.5 Acquired absence of leg at or below knee
0.659 0.341 0.000
D72 Other disorders of white blood cells
0.658 0.342 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.658 0.342 0.000
Z96.9 Presence of functional implant, unspecified
0.657 0.342 0.000
Z96.5 Presence of tooth-root and mandibular implants
0.657 0.342 0.000
Z96.4 Presence of endocrine implants
0.657 0.342 0.000
Z96.3 Presence of artificial larynx
0.657 0.342 0.000
Y85.9 Sequelae of other and unspecified transport accidents
0.657 0.342 0.000
Z51.6 Desensitisation to allergens
0.657 0.343 0.000
Y89 Sequelae of other external causes
0.656 0.344 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.656 0.344 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.656 0.344 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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