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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74522278
log Bayes Factor = 14.9957
Chromosome 7   position 5,156,883  (GRCh37) Explore rs74522278 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
I25 Chronic ischaemic heart disease
0.999 0.001 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.997 0.003 0.000
M70-M79 Other soft tissue disorders
0.995 0.005 0.000
E78.0 Pure hypercholesterolaemia
0.994 0.006 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.992 0.008 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.991 0.009 0.000
E70-E90 Metabolic disorders
0.991 0.009 0.000
Chapter VI Diseases of the nervous system
0.990 0.010 0.000
H04 Disorders of lachrymal system
0.990 0.010 0.000
I30-I52 Other forms of heart disease
0.981 0.019 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.975 0.025 0.000
G40-G47 Episodic and paroxysmal disorders
0.973 0.027 0.000
Chapter V Mental and behavioural disorders
0.971 0.029 0.000
M45-M49 Spondylopathies
0.969 0.031 0.000
H30-H36 Disorders of choroid and retina
0.968 0.032 0.000
H25-H28 Disorders of lens
0.958 0.042 0.000
I21 Acute myocardial infarction
0.957 0.043 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.954 0.046 0.000
H04.2 Epiphora
0.952 0.048 0.000
G40 Epilepsy
0.951 0.049 0.000
Chapter X Diseases of the respiratory system
0.949 0.051 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.947 0.053 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.943 0.057 0.000
H25 Senile cataract
0.940 0.060 0.000
I44 Atrioventricular and left bundle-branch block
0.940 0.060 0.000
M47 Spondylosis
0.939 0.061 0.000
E10-E14 Diabetes mellitus
0.936 0.064 0.000
J40-J47 Chronic lower respiratory diseases
0.928 0.072 0.000
M75 Shoulder lesions
0.924 0.076 0.000
M79.6 Pain in limb
0.917 0.083 0.000
G90-G99 Other disorders of the nervous system
0.913 0.087 0.000
M20-M25 Other joint disorders
0.912 0.088 0.000
Chapter VIII Diseases of the ear and mastoid process
0.911 0.089 0.000
E20-E35 Disorders of other endocrine glands
0.909 0.091 0.000
M47.8 Other spondylosis
0.906 0.094 0.000
H35 Other retinal disorders
0.904 0.096 0.000
S80-S89 Injuries to the knee and lower leg
0.902 0.098 0.000
J47 Bronchiectasis
0.901 0.099 0.000
F30-F39 Mood [affective] disorders
0.901 0.099 0.000
I34 Nonrheumatic mitral valve disorders
0.895 0.105 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.891 0.109 0.000
I51 Complications and ill-defined descriptions of heart disease
0.891 0.109 0.000
G40.9 Epilepsy, unspecified
0.889 0.111 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.886 0.114 0.000
I21.4 Acute subendocardial myocardial infarction
0.882 0.118 0.000
I22 Subsequent myocardial infarction
0.882 0.118 0.000
M25 Other joint disorders, not elsewhere classified
0.881 0.119 0.000
L60-L75 Disorders of skin appendages
0.881 0.119 0.000
Chapter I Certain infectious and parasitic diseases
0.876 0.124 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.872 0.128 0.000
S82 Fracture of lower leg, including ankle
0.872 0.128 0.000
H02 Other disorders of eyelid
0.872 0.128 0.000
I25.2 Old myocardial infarction
0.870 0.130 0.000
H25.8 Other senile cataract
0.863 0.137 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.859 0.141 0.000
I46 Cardiac arrest
0.858 0.142 0.000
I44.7 Left bundle-branch block, unspecified
0.858 0.142 0.000
H53-H54 Visual disturbances and blindness
0.856 0.144 0.000
L40-L45 Papulosquamous disorders
0.855 0.145 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.855 0.145 0.000
F32 Depressive episode
0.850 0.150 0.000
H25.1 Senile nuclear cataract
0.846 0.154 0.000
M50-M54 Other dorsopathies
0.846 0.154 0.000
J44 Other chronic obstructive pulmonary disease
0.843 0.157 0.000
M75.1 Rotator cuff syndrome
0.837 0.163 0.000
F41 Other anxiety disorders
0.836 0.164 0.000
I60-I69 Cerebrovascular diseases
0.832 0.168 0.000
E11 Non-insulin-dependent diabetes mellitus
0.829 0.171 0.000
M25.5 Pain in joint
0.828 0.172 0.000
H25.0 Senile incipient cataract
0.827 0.173 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.826 0.174 0.000
I25.1 Atherosclerotic heart disease
0.821 0.179 0.000
S60-S69 Injuries to the wrist and hand
0.820 0.180 0.000
M47.82 Other spondylosis (Cervical region)
0.820 0.180 0.000
B35-B49 Mycoses
0.819 0.181 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.817 0.183 0.000
E10 Insulin-dependent diabetes mellitus
0.817 0.183 0.000
H31 Other disorders of choroid
0.816 0.184 0.000
G47 Sleep disorders
0.812 0.187 0.000
H35.3 Degeneration of macula and posterior pole
0.812 0.188 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.805 0.194 0.000
M79.5 Residual foreign body in soft tissue
0.803 0.197 0.000
F32.9 Depressive episode, unspecified
0.802 0.198 0.000
H55-H59 Other disorders of eye and adnexa
0.800 0.200 0.000
L40 Psoriasis
0.799 0.201 0.000
S82.6 Fracture of lateral malleolus
0.799 0.201 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.797 0.203 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.797 0.203 0.000
H36 Retinal disorders in diseases classified elsewhere
0.795 0.205 0.000
M79.0 Rheumatism, unspecified
0.791 0.209 0.000
I34.0 Mitral (valve) insufficiency
0.789 0.211 0.000
I77 Other disorders of arteries and arterioles
0.788 0.212 0.000
H65-H75 Diseases of middle ear and mastoid
0.786 0.214 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.785 0.215 0.000
S20-S29 Injuries to the thorax
0.785 0.215 0.000
I21.9 Acute myocardial infarction, unspecified
0.785 0.215 0.000
B25-B34 Other viral diseases
0.782 0.218 0.000
H00 Hordeolum and chalazion
0.781 0.219 0.000
M79.7 Fibromyalgia
0.780 0.220 0.000
B37 Candidiasis
0.778 0.222 0.000
M77 Other enthesopathies
0.778 0.222 0.000
H90-H95 Other disorders of ear
0.777 0.223 0.000
I46.0 Cardiac arrest with successful resuscitation
0.777 0.223 0.000
M79.60 Pain in limb (Multiple sites)
0.776 0.224 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.776 0.224 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.776 0.224 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.775 0.225 0.000
G93 Other disorders of brain
0.774 0.226 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.773 0.227 0.000
M86-M90 Other osteopathies
0.770 0.230 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.769 0.231 0.000
M25.4 Effusion of joint
0.769 0.231 0.000
E11.3 With ophthalmic complications
0.769 0.231 0.000
I51.8 Other ill-defined heart diseases
0.769 0.231 0.000
I47 Paroxysmal tachycardia
0.768 0.232 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.767 0.233 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.767 0.233 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.766 0.234 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.766 0.234 0.000
J00-J06 Acute upper respiratory infections
0.765 0.235 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.764 0.235 0.000
M46 Other inflammatory spondylopathies
0.760 0.240 0.000
I44.2 Atrioventricular block, complete
0.759 0.241 0.000
M47.86 Other spondylosis (Lumbar region)
0.758 0.242 0.000
I25.5 Ischaemic cardiomyopathy
0.758 0.242 0.000
I51.7 Cardiomegaly
0.757 0.243 0.000
G91 Hydrocephalus
0.756 0.244 0.000
M65-M68 Disorders of synovium and tendon
0.754 0.246 0.000
I05-I09 Chronic rheumatic heart diseases
0.753 0.247 0.000
M47.1 Other spondylosis with myelopathy
0.751 0.249 0.000
I44.1 Atrioventricular block, second degree
0.748 0.252 0.000
I34.1 Mitral (valve) prolapse
0.747 0.253 0.000
F41.2 Mixed anxiety and depressive disorder
0.747 0.253 0.000
S82.60 Fracture of lateral malleolus (closed)
0.747 0.253 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.747 0.253 0.000
M79.67 Pain in limb (Ankle and foot)
0.746 0.254 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.744 0.256 0.000
M75.5 Bursitis of shoulder
0.744 0.256 0.000
I44.0 Atrioventricular block, first degree
0.743 0.257 0.000
M79.62 Pain in limb (Upper arm)
0.742 0.258 0.000
H02.8 Other specified disorders of eyelid
0.742 0.258 0.000
L50-L54 Urticaria and erythema
0.740 0.260 0.000
M79.8 Other specified soft tissue disorders
0.740 0.260 0.000
I67 Other cerebrovascular diseases
0.739 0.261 0.000
H34 Retinal vascular occlusions
0.738 0.261 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.738 0.262 0.000
H35.9 Retinal disorder, unspecified
0.738 0.262 0.000
M25.57 Pain in joint (Ankle and foot)
0.737 0.263 0.000
H02.0 Entropion and trichiasis of eyelid
0.737 0.263 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.737 0.263 0.000
S82.1 Fracture of upper end of tibia
0.736 0.264 0.000
H53 Visual disturbances
0.734 0.266 0.000
M79.63 Pain in limb (Forearm)
0.732 0.268 0.000
M54 Dorsalgia
0.731 0.269 0.000
L72.1 Trichilemmal cyst
0.731 0.269 0.000
E13 Other specified diabetes mellitus
0.730 0.269 0.000
S10-S19 Injuries to the neck
0.730 0.269 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.730 0.270 0.000
G20-G26 Extrapyramidal and movement disorders
0.730 0.270 0.000
M45 Ankylosing spondylitis
0.727 0.273 0.000
L60 Nail disorders
0.727 0.273 0.000
S82.2 Fracture of shaft of tibia
0.726 0.274 0.000
J42 Unspecified chronic bronchitis
0.725 0.275 0.000
H01 Other inflammation of eyelid
0.725 0.275 0.000
M31 Other necrotising vasculopathies
0.724 0.276 0.000
E21.0 Primary hyperparathyroidism
0.724 0.276 0.000
G30-G32 Other degenerative diseases of the nervous system
0.724 0.276 0.000
H43-H45 Disorders of vitreous body and globe
0.723 0.277 0.000
M79.64 Pain in limb (Hand)
0.723 0.277 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.723 0.277 0.000
Chapter XIV Diseases of the genitourinary system
0.723 0.277 0.000
G95 Other diseases of spinal cord
0.722 0.278 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.722 0.278 0.000
E27 Other disorders of adrenal gland
0.721 0.278 0.000
H02.3 Blepharochalasis
0.720 0.280 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.720 0.280 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.719 0.281 0.000
G47.3 Sleep apnoea
0.718 0.282 0.000
M80-M85 Disorders of bone density and structure
0.718 0.282 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.717 0.283 0.000
H10-H13 Disorders of conjunctiva
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
M75.3 Calcific tendinitis of shoulder
0.717 0.283 0.000
E40-E46 Malnutrition
0.716 0.284 0.000
I25.6 Silent myocardial ischaemia
0.716 0.284 0.000
I25.4 Coronary artery aneurysm
0.716 0.284 0.000
I25.3 Aneurysm of heart
0.716 0.284 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.716 0.284 0.000
H35.0 Background retinopathy and retinal vascular changes
0.715 0.285 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.715 0.285 0.000
H05 Disorders of orbit
0.715 0.285 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.715 0.285 0.000
B34 Viral infection of unspecified site
0.715 0.285 0.000
E50-E64 Other nutritional deficiencies
0.714 0.286 0.000
M76 Enthesopathies of lower limb, excluding foot
0.714 0.286 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.714 0.286 0.000
M71 Other bursopathies
0.714 0.286 0.000
M23 Internal derangement of knee
0.713 0.287 0.000
M24 Other specific joint derangements
0.713 0.287 0.000
Chapter XX External causes of morbidity and mortality
0.713 0.287 0.000
G44 Other headache syndromes
0.712 0.288 0.000
N40-N51 Diseases of male genital organs
0.711 0.289 0.000
I20 Angina pectoris
0.711 0.289 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.711 0.289 0.000
E78.8 Other disorders of lipoprotein metabolism
0.711 0.289 0.000
E78.6 Lipoprotein deficiency
0.711 0.289 0.000
E78.4 Other hyperlipidaemia
0.711 0.289 0.000
E78.3 Hyperchylomicronaemia
0.711 0.289 0.000
E78.2 Mixed hyperlipidaemia
0.711 0.289 0.000
E78.1 Pure hyperglyceridaemia
0.711 0.289 0.000
E85 Amyloidosis
0.710 0.289 0.000
E84 Cystic fibrosis
0.710 0.289 0.000
E79 Disorders of purine and pyrimidine metabolism
0.710 0.289 0.000
E77 Disorders of glycoprotein metabolism
0.710 0.289 0.000
E76 Disorders of glycosaminoglycan metabolism
0.710 0.289 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.710 0.289 0.000
E74 Other disorders of carbohydrate metabolism
0.710 0.289 0.000
E73 Lactose intolerance
0.710 0.289 0.000
E72 Other disorders of amino-acid metabolism
0.710 0.289 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.710 0.289 0.000
E70 Disorders of aromatic amino-acid metabolism
0.710 0.289 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.710 0.289 0.000
G70-G73 Diseases of myoneural junction and muscle
0.710 0.290 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.710 0.290 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.710 0.290 0.000
L40.9 Psoriasis, unspecified
0.710 0.290 0.000
H04.9 Disorder of lachrymal system, unspecified
0.710 0.290 0.000
H04.8 Other disorders of lachrymal system
0.710 0.290 0.000
H04.6 Other changes in lachrymal passages
0.710 0.290 0.000
H04.4 Chronic inflammation of lachrymal passages
0.710 0.290 0.000
H04.3 Acute and unspecified inflammation of lachrymal passages
0.710 0.290 0.000
H04.0 Dacryoadenitis
0.710 0.290 0.000
E10.9 Without complications
0.709 0.291 0.000
H31.0 Chorioretinal scars
0.708 0.292 0.000
M47.2 Other spondylosis with radiculopathy
0.708 0.292 0.000
H04.1 Other disorders of lachrymal gland
0.706 0.294 0.000
E88 Other metabolic disorders
0.703 0.296 0.000
I52 Other heart disorders in diseases classified elsewhere
0.703 0.297 0.000
I48 Atrial fibrillation and flutter
0.703 0.297 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.703 0.297 0.000
I41 Myocarditis in diseases classified elsewhere
0.703 0.297 0.000
I40 Acute myocarditis
0.703 0.297 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.703 0.297 0.000
I37 Pulmonary valve disorders
0.703 0.297 0.000
I36 Nonrheumatic tricuspid valve disorders
0.703 0.297 0.000
I33 Acute and subacute endocarditis
0.703 0.297 0.000
I32 Pericarditis in diseases classified elsewhere
0.703 0.297 0.000
I30 Acute pericarditis
0.703 0.297 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.703 0.297 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.703 0.297 0.000
M75.0 Adhesive capsulitis of shoulder
0.701 0.299 0.000
M79.9 Soft tissue disorder, unspecified
0.699 0.301 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.699 0.301 0.000
M79.3 Panniculitis, unspecified
0.699 0.301 0.000
M79.2 Neuralgia and neuritis, unspecified
0.699 0.301 0.000
M79.1 Myalgia
0.699 0.301 0.000
I61 Intracerebral haemorrhage
0.698 0.302 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.698 0.302 0.000
G41 Status epilepticus
0.698 0.302 0.000
J60-J70 Lung diseases due to external agents
0.698 0.302 0.000
I74 Arterial embolism and thrombosis
0.697 0.302 0.000
L40.5 Arthropathic psoriasis
0.697 0.303 0.000
M25.9 Joint disorder, unspecified
0.697 0.303 0.000
F99-F99 Unspecified mental disorder
0.696 0.304 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.696 0.304 0.000
F80-F89 Disorders of psychological development
0.696 0.304 0.000
F70-F79 Mental retardation
0.696 0.304 0.000
F60-F69 Disorders of adult personality and behaviour
0.696 0.304 0.000
F43 Reaction to severe stress, and adjustment disorders
0.695 0.305 0.000
E00-E07 Disorders of thyroid gland
0.695 0.305 0.000
M49 Spondylopathies in diseases classified elsewhere
0.694 0.305 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.694 0.306 0.000
H30 Chorioretinal inflammation
0.694 0.306 0.000
S50-S59 Injuries to the elbow and forearm
0.692 0.308 0.000
B37.0 Candidal stomatitis
0.692 0.308 0.000
M25.54 Pain in joint (Hand)
0.692 0.308 0.000
Chapter XXII Codes for special purposes
0.692 0.308 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.690 0.310 0.000
M70.4 Prepatellar bursitis
0.689 0.311 0.000
N40 Hyperplasia of prostate
0.689 0.311 0.000
M25.46 Effusion of joint (Lower leg)
0.688 0.312 0.000
E29 Testicular dysfunction
0.688 0.312 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.687 0.313 0.000
H27 Other disorders of lens
0.687 0.313 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.686 0.314 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.686 0.314 0.000
G40.8 Other epilepsy
0.682 0.318 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.682 0.318 0.000
G40.5 Special epileptic syndromes
0.682 0.318 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.682 0.318 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.682 0.318 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.682 0.318 0.000
L72.0 Epidermal cyst
0.682 0.318 0.000
M21 Other acquired deformities of limbs
0.681 0.319 0.000
I73 Other peripheral vascular diseases
0.680 0.320 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.680 0.320 0.000
T79-T79 Certain early complications of trauma
0.679 0.321 0.000
T33-T35 Frostbite
0.679 0.321 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.679 0.321 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.679 0.321 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.679 0.321 0.000
T00-T07 Injuries involving multiple body regions
0.679 0.321 0.000
M25.56 Pain in joint (Lower leg)
0.679 0.321 0.000
S61 Open wound of wrist and hand
0.679 0.321 0.000
M79.54 Residual foreign body in soft tissue (Hand)
0.679 0.321 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.679 0.321 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.679 0.321 0.000
L10-L14 Bullous disorders
0.676 0.324 0.000
B37.9 Candidiasis, unspecified
0.676 0.324 0.000
I47.2 Ventricular tachycardia
0.676 0.324 0.000
I50 Heart failure
0.675 0.325 0.000
H25.2 Senile cataract, morgagnian type
0.674 0.326 0.000
I44.6 Other and unspecified fascicular block
0.674 0.326 0.000
I44.5 Left posterior fascicular block
0.674 0.326 0.000
I44.4 Left anterior fascicular block
0.674 0.326 0.000
I44.3 Other and unspecified atrioventricular block
0.674 0.326 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.673 0.326 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.673 0.327 0.000
M23.3 Other meniscus derangements
0.672 0.328 0.000
H36.0 Diabetic retinopathy
0.672 0.328 0.000
M47.9 Spondylosis, unspecified
0.672 0.328 0.000
E12 Malnutrition-related diabetes mellitus
0.671 0.329 0.000
M50 Cervical disk disorders
0.669 0.331 0.000
J95-J99 Other diseases of the respiratory system
0.668 0.331 0.000
L73 Other follicular disorders
0.667 0.333 0.000
T66-T78 Other and unspecified effects of external causes
0.667 0.333 0.000
B34.9 Viral infection, unspecified
0.667 0.333 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.666 0.334 0.000
J41 Simple and mucopurulent chronic bronchitis
0.665 0.334 0.000
I67.8 Other specified cerebrovascular diseases
0.665 0.335 0.000
L20-L30 Dermatitis and eczema
0.664 0.336 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.663 0.337 0.000
M75.8 Other shoulder lesions
0.663 0.337 0.000
M75.9 Shoulder lesion, unspecified
0.663 0.337 0.000
M75.2 Bicipital tendinitis
0.663 0.337 0.000
M40-M43 Deforming dorsopathies
0.662 0.338 0.000
G43 Migraine
0.662 0.338 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.661 0.339 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.660 0.340 0.000
G93.9 Disorder of brain, unspecified
0.660 0.340 0.000
H80-H83 Diseases of inner ear
0.659 0.341 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.659 0.341 0.000
S81 Open wound of lower leg
0.658 0.342 0.000
M79.69 Pain in limb (Site unspecified)
0.657 0.342 0.000
M79.68 Pain in limb (Other)
0.657 0.342 0.000
M79.61 Pain in limb (Shoulder region)
0.657 0.342 0.000
A80-A89 Viral infections of the central nervous system
0.656 0.344 0.000
S82.3 Fracture of lower end of tibia
0.656 0.344 0.000
S82.0 Fracture of patella
0.655 0.345 0.000
M48 Other spondylopathies
0.655 0.345 0.000
G96 Other disorders of central nervous system
0.655 0.345 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.655 0.345 0.000
G90 Disorders of autonomic nervous system
0.655 0.345 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.655 0.345 0.000
G92 Toxic encephalopathy
0.655 0.345 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.654 0.346 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.654 0.346 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.654 0.346 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.654 0.346 0.000
M34 Systemic sclerosis
0.654 0.346 0.000
M33 Dermatopolymyositis
0.654 0.346 0.000
M32 Systemic lupus erythematosus
0.654 0.346 0.000
M30 Polyarteritis nodosa and related conditions
0.654 0.346 0.000
S20 Superficial injury of thorax
0.653 0.346 0.000
H40-H42 Glaucoma
0.653 0.347 0.000
E83 Disorders of mineral metabolism
0.653 0.347 0.000
I31 Other diseases of pericardium
0.653 0.347 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.653 0.347 0.000
O85-O92 Complications predominantly related to the puerperium
0.653 0.347 0.000
H54 Blindness and low vision
0.652 0.347 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.652 0.348 0.000
E34 Other endocrine disorders
0.652 0.348 0.000
E32 Diseases of thymus
0.652 0.348 0.000
E31 Polyglandular dysfunction
0.652 0.348 0.000
E30 Disorders of puberty, not elsewhere classified
0.652 0.348 0.000
E28 Ovarian dysfunction
0.652 0.348 0.000
E26 Hyperaldosteronism
0.652 0.348 0.000
E25 Adrenogenital disorders
0.652 0.348 0.000
E24 Cushing's syndrome
0.652 0.348 0.000
E23 Hypofunction and other disorders of pituitary gland
0.652 0.348 0.000
E22 Hyperfunction of pituitary gland
0.652 0.348 0.000
E20 Hypoparathyroidism
0.652 0.348 0.000
H60-H62 Diseases of external ear
0.651 0.349 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.651 0.349 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.650 0.350 0.000
I20.8 Other forms of angina pectoris
0.650 0.350 0.000
M47.89 Other spondylosis (Site unspecified)
0.649 0.350 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.649 0.350 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.649 0.350 0.000
M47.84 Other spondylosis (Thoracic region)
0.649 0.350 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.649 0.350 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.649 0.350 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.649 0.350 0.000
S90-S99 Injuries to the ankle and foot
0.649 0.351 0.000
H35.7 Separation of retinal layers
0.648 0.352 0.000
H35.6 Retinal haemorrhage
0.648 0.352 0.000
H35.5 Hereditary retinal dystrophy
0.648 0.352 0.000
H35.4 Peripheral retinal degeneration
0.648 0.352 0.000
H35.2 Other proliferative retinopathy
0.648 0.352 0.000
H35.1 Retinopathy of prematurity
0.648 0.352 0.000
I77.1 Stricture of artery
0.648 0.352 0.000
J46 Status asthmaticus
0.648 0.352 0.000
S00-S09 Injuries to the head
0.648 0.352 0.000
H71 Cholesteatoma of middle ear
0.647 0.352 0.000
S89 Other and unspecified injuries of lower leg
0.646 0.353 0.000
S88 Traumatic amputation of lower leg
0.646 0.353 0.000
S87 Crushing injury of lower leg
0.646 0.353 0.000
S86 Injury of muscle and tendon at lower leg level
0.646 0.353 0.000
S85 Injury of blood vessels at lower leg level
0.646 0.353 0.000
S84 Injury of nerves at lower leg level
0.646 0.353 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.646 0.353 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.646 0.354 0.000
F38 Other mood [affective] disorders
0.646 0.354 0.000
F34 Persistent mood [affective] disorders
0.646 0.354 0.000
F33 Recurrent depressive disorder
0.646 0.354 0.000
F30 Manic episode
0.646 0.354 0.000
F39 Unspecified mood [affective] disorder
0.646 0.354 0.000
F31 Bipolar affective disorder
0.646 0.354 0.000
G91.9 Hydrocephalus, unspecified
0.643 0.357 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.642 0.358 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.642 0.358 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.642 0.358 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.642 0.358 0.000
H35.8 Other specified retinal disorders
0.641 0.359 0.000
I51.9 Heart disease, unspecified
0.641 0.359 0.000
I42 Cardiomyopathy
0.640 0.360 0.000
M79.79 Fibromyalgia (Site unspecified)
0.640 0.360 0.000
H02.1 Ectropion of eyelid
0.640 0.360 0.000
I70 Atherosclerosis
0.640 0.360 0.000
S82.10 Fracture of upper end of tibia (closed)
0.639 0.361 0.000
F48 Other neurotic disorders
0.639 0.361 0.000
F44 Dissociative [conversion] disorders
0.639 0.361 0.000
F42 Obsessive-compulsive disorder
0.639 0.361 0.000
I51.6 Cardiovascular disease, unspecified
0.639 0.361 0.000
I51.5 Myocardial degeneration
0.639 0.361 0.000
I51.4 Myocarditis, unspecified
0.639 0.361 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.639 0.361 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.639 0.361 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.639 0.361 0.000
I51.0 Cardiac septal defect, acquired
0.639 0.361 0.000
M72 Fibroblastic disorders
0.638 0.361 0.000
H25.9 Senile cataract, unspecified
0.637 0.363 0.000
J03 Acute tonsillitis
0.637 0.363 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.636 0.364 0.000
I72 Other aneurysm
0.636 0.364 0.000
I78 Diseases of capillaries
0.635 0.365 0.000
E10.3 With ophthalmic complications
0.634 0.365 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.634 0.366 0.000
J43 Emphysema
0.634 0.366 0.000
I77.8 Other specified disorders of arteries and arterioles
0.634 0.366 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.633 0.367 0.000
I22.8 Subsequent myocardial infarction of other sites
0.632 0.368 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.632 0.368 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.632 0.368 0.000
M25.8 Other specified joint disorders
0.632 0.368 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.632 0.368 0.000
M25.3 Other instability of joint
0.632 0.368 0.000
M25.2 Flail joint
0.632 0.368 0.000
M25.1 Fistula of joint
0.632 0.368 0.000
M25.0 Haemarthrosis
0.632 0.368 0.000
E16 Other disorders of pancreatic internal secretion
0.632 0.368 0.000
L75 Apocrine sweat disorders
0.631 0.369 0.000
L74 Eccrine sweat disorders
0.631 0.369 0.000
L70 Acne
0.631 0.369 0.000
L68 Hypertrichosis
0.631 0.369 0.000
L67 Hair colour and hair shaft abnormalities
0.631 0.369 0.000
L66 Cicatricial alopecia [scarring hair loss]
0.631 0.369 0.000
L65 Other nonscarring hair loss
0.631 0.369 0.000
L64 Androgenic alopecia
0.631 0.369 0.000
L63 Alopecia areata
0.631 0.369 0.000
L62 Nail disorders in diseases classified elsewhere
0.631 0.369 0.000
H02.5 Other disorders affecting eyelid function
0.630 0.370 0.000
B99-B99 Other infectious diseases
0.628 0.372 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.628 0.372 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.628 0.372 0.000
B65-B83 Helminthiases
0.628 0.372 0.000
B50-B64 Protozoal diseases
0.628 0.372 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.628 0.372 0.000
B15-B19 Viral hepatitis
0.628 0.372 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.628 0.372 0.000
A75-A79 Rickettsioses
0.628 0.372 0.000
A70-A74 Other diseases caused by chlamydiae
0.628 0.372 0.000
A65-A69 Other spirochaetal diseases
0.628 0.372 0.000
A20-A28 Certain zoonotic bacterial diseases
0.628 0.372 0.000
A15-A19 Tuberculosis
0.628 0.372 0.000
L71 Rosacea
0.627 0.373 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.627 0.373 0.000
H00.1 Chalazion
0.627 0.373 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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