TreeWAS – Variant ID: rs7453498

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	1.000	0.000	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	1.000	0.000	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	1.000	0.000	0.000
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
E10.9 Without complications	1.000	0.000	0.000
E10.3 With ophthalmic complications	1.000	0.000	0.000
E10.1 With ketoacidosis	1.000	0.000	0.000
E11.9 Without complications	1.000	0.000	0.000
H36.0 Diabetic retinopathy	1.000	0.000	0.000
J33.9 Nasal polyp, unspecified	1.000	0.000	0.000
K51.9 Ulcerative colitis, unspecified	0.000	0.000	1.000
K90.0 Coeliac disease	1.000	0.000	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	1.000	0.000	0.000
M06.9 Rheumatoid arthritis, unspecified	1.000	0.000	0.000
E14 Unspecified diabetes mellitus	1.000	0.000	0.000
E11 Non-insulin-dependent diabetes mellitus	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
G35 Multiple sclerosis	0.000	0.000	1.000
J33 Nasal polyp	1.000	0.000	0.000
M06 Other rheumatoid arthritis	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
J40-J47 Chronic lower respiratory diseases	1.000	0.000	0.000
M20-M25 Other joint disorders	1.000	0.000	0.000
M05-M14 Inflammatory polyarthropathies	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
Chapter X Diseases of the respiratory system	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
E16.2 Hypoglycaemia, unspecified	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	1.000	0.000	0.000
J33.0 Polyp of nasal cavity	1.000	0.000	0.000
M35.3 Polymyalgia rheumatica	1.000	0.000	0.000
M05 Seropositive rheumatoid arthritis	1.000	0.000	0.000
J30-J39 Other diseases of upper respiratory tract	1.000	0.000	0.000
E10.4 With neurological complications	1.000	0.000	0.000
K51 Ulcerative colitis	0.000	0.000	1.000
M35 Other systemic involvement of connective tissue	1.000	0.000	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	1.000	0.000	0.000
E03 Other hypothyroidism	1.000	0.000	0.000
E16 Other disorders of pancreatic internal secretion	1.000	0.000	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	1.000	0.000	0.000
J44 Other chronic obstructive pulmonary disease	1.000	0.000	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	1.000	0.000	0.000
J45 Asthma	0.999	0.001	0.000
J45.9 Asthma, unspecified	0.999	0.001	0.000
Chapter XI Diseases of the digestive system	0.999	0.001	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.999	0.001	0.000
E14.3 With ophthalmic complications	0.999	0.001	0.000
M65-M68 Disorders of synovium and tendon	0.999	0.001	0.000
E14.9 Without complications	0.999	0.001	0.000
M25 Other joint disorders, not elsewhere classified	0.999	0.001	0.000
E10.5 With peripheral circulatory complications	0.999	0.001	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.998	0.002	0.000
M65 Synovitis and tenosynovitis	0.998	0.002	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.998	0.002	0.000
M25.4 Effusion of joint	0.998	0.002	0.000
J33.8 Other polyp of sinus	0.997	0.003	0.000
J32 Chronic sinusitis	0.996	0.004	0.000
E11.1 With ketoacidosis	0.996	0.004	0.000
M25.46 Effusion of joint (Lower leg)	0.996	0.004	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.996	0.004	0.000
E05.9 Thyrotoxicosis, unspecified	0.996	0.004	0.000
K90 Intestinal malabsorption	0.996	0.004	0.000
K70-K77 Diseases of liver	0.996	0.004	0.000
E70-E90 Metabolic disorders	0.996	0.004	0.000
K55-K64 Other diseases of intestines	0.995	0.005	0.000
K90-K93 Other diseases of the digestive system	0.995	0.005	0.000
M31 Other necrotising vasculopathies	0.995	0.005	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.995	0.005	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.000	0.007	0.993
E10.2 With renal complications	0.993	0.007	0.000
M31.6 Other giant cell arteritis	0.993	0.007	0.000
K58.0 Irritable bowel syndrome with diarrhoea	0.992	0.008	0.000
K58 Irritable bowel syndrome	0.992	0.008	0.000
E78.0 Pure hypercholesterolaemia	0.990	0.010	0.000
M06.0 Seronegative rheumatoid arthritis	0.988	0.012	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.987	0.013	0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.984	0.016	0.000
K74 Fibrosis and cirrhosis of liver	0.984	0.016	0.000
M06.3 Rheumatoid nodule	0.982	0.018	0.000
K60 Fissure and fistula of anal and rectal regions	0.982	0.018	0.000
K74.3 Primary biliary cirrhosis	0.982	0.018	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.980	0.020	0.000
E11.3 With ophthalmic complications	0.980	0.020	0.000
J32.9 Chronic sinusitis, unspecified	0.980	0.020	0.000
K51.2 Ulcerative (chronic) proctitis	0.000	0.026	0.974
K57 Diverticular disease of intestine	0.973	0.027	0.000
J46 Status asthmaticus	0.972	0.028	0.000
K57.3 Diverticular disease of large intestine without perforation or abscess	0.972	0.028	0.000
E78.5 Hyperlipidaemia, unspecified	0.970	0.030	0.000
E10.8 With unspecified complications	0.969	0.031	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.969	0.031	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.965	0.035	0.000
K51.8 Other ulcerative colitis	0.000	0.038	0.962
E11.5 With peripheral circulatory complications	0.961	0.039	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.961	0.039	0.000
K75 Other inflammatory liver diseases	0.959	0.041	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.953	0.047	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.953	0.047	0.000
M65.4 Radial styloid tenosynovitis [de Quervain]	0.952	0.048	0.000
E89.0 Postprocedural hypothyroidism	0.951	0.049	0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.950	0.050	0.000
E40-E46 Malnutrition	0.948	0.052	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.945	0.055	0.000
M34 Systemic sclerosis	0.944	0.056	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.022	0.057	0.921
J32.8 Other chronic sinusitis	0.937	0.063	0.000
K75.4 Autoimmune hepatitis	0.937	0.063	0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.936	0.064	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.919	0.081	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.913	0.087	0.000
E14.6 With other specified complications	0.912	0.088	0.000
E46 Unspecified protein-energy malnutrition	0.911	0.089	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.907	0.093	0.000
G37 Other demyelinating diseases of central nervous system	0.005	0.094	0.902
J86 Pyothorax	0.906	0.094	0.000
K73 Chronic hepatitis, not elsewhere classified	0.903	0.097	0.000
K60.0 Acute anal fissure	0.902	0.098	0.000
E10.6 With other specified complications	0.901	0.099	0.000
E10.0 With coma	0.897	0.103	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.896	0.104	0.000
Chapter VIII Diseases of the ear and mastoid process	0.892	0.108	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.892	0.108	0.000
M25.40 Effusion of joint (Multiple sites)	0.892	0.108	0.000
J32.4 Chronic pansinusitis	0.886	0.114	0.000
E89.2 Postprocedural hypoparathyroidism	0.883	0.117	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.882	0.118	0.000
M06.4 Inflammatory polyarthropathy	0.880	0.120	0.000
K60.5 Anorectal fistula	0.880	0.120	0.000
K60.2 Anal fissure, unspecified	0.877	0.123	0.000
E88 Other metabolic disorders	0.876	0.124	0.000
E89.3 Postprocedural hypopituitarism	0.874	0.126	0.000
M06.34 Rheumatoid nodule (Hand)	0.873	0.127	0.000
M35.1 Other overlap syndromes	0.868	0.132	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.867	0.133	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.001	0.136	0.863
M15-M19 Arthrosis	0.860	0.140	0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)	0.858	0.142	0.000
K51.5 Mucosal proctocolitis	0.000	0.143	0.857
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.856	0.144	0.000
K51.4 Pseudopolyposis of colon	0.000	0.148	0.852
M05.8 Other seropositive rheumatoid arthritis	0.852	0.148	0.000
E11.0 With coma	0.851	0.149	0.000
M18 Arthrosis of first carpometacarpal joint	0.847	0.153	0.000
E14.1 With ketoacidosis	0.846	0.154	0.000
M60-M63 Disorders of muscles	0.842	0.158	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.842	0.158	0.000
E10.7 With multiple complications	0.840	0.160	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.840	0.160	0.000
M86-M90 Other osteopathies	0.839	0.160	0.000
E14.8 With unspecified complications	0.839	0.161	0.000
E78.2 Mixed hyperlipidaemia	0.838	0.162	0.000
L40-L45 Papulosquamous disorders	0.838	0.162	0.000
H60-H62 Diseases of external ear	0.837	0.163	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.835	0.165	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.832	0.168	0.000
L43 Lichen planus	0.832	0.168	0.000
M34.8 Other forms of systemic sclerosis	0.831	0.169	0.000
E07 Other disorders of thyroid	0.830	0.170	0.000
J86.0 Pyothorax with fistula	0.826	0.174	0.000
L43.9 Lichen planus, unspecified	0.825	0.175	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.821	0.179	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.821	0.179	0.000
M34.1 CR(E)ST syndrome	0.820	0.180	0.000
K50-K52 Noninfective enteritis and colitis	0.772	0.180	0.048
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.819	0.181	0.000
K60.1 Chronic anal fissure	0.818	0.182	0.000
K74.5 Biliary cirrhosis, unspecified	0.809	0.191	0.000
J95-J99 Other diseases of the respiratory system	0.808	0.192	0.000
J37 Chronic laryngitis and laryngotracheitis	0.806	0.194	0.000
M25.47 Effusion of joint (Ankle and foot)	0.806	0.194	0.000
M05.1 Rheumatoid lung disease	0.805	0.195	0.000
E14.5 With peripheral circulatory complications	0.805	0.195	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.802	0.198	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.800	0.200	0.000
M66 Spontaneous rupture of synovium and tendon	0.799	0.201	0.000
E06 Thyroiditis	0.798	0.202	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.798	0.202	0.000
J86.9 Pyothorax without fistula	0.797	0.203	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.002	0.204	0.795
M60 Myositis	0.795	0.205	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.794	0.205	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.794	0.206	0.000
M65.8 Other synovitis and tenosynovitis	0.793	0.207	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.793	0.207	0.000
K75.8 Other specified inflammatory liver diseases	0.792	0.208	0.000
K73.9 Chronic hepatitis, unspecified	0.792	0.208	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.784	0.208	0.008
J33.1 Polypoid sinus degeneration	0.790	0.210	0.000
M08 Juvenile arthritis	0.789	0.211	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.788	0.212	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.785	0.215	0.000
M14 Arthropathies in other diseases classified elsewhere	0.784	0.216	0.000
L40 Psoriasis	0.783	0.217	0.000
E78.1 Pure hyperglyceridaemia	0.782	0.218	0.000
E14.0 With coma	0.782	0.218	0.000
M15 Polyarthrosis	0.780	0.220	0.000
D60-D64 Aplastic and other anaemias	0.779	0.220	0.001
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.779	0.221	0.000
H61 Other disorders of external ear	0.777	0.223	0.000
D64 Other anaemias	0.776	0.224	0.000
D64.9 Anaemia, unspecified	0.775	0.225	0.000
M35.7 Hypermobility syndrome	0.768	0.232	0.000
J43 Emphysema	0.767	0.233	0.000
M31.7 Microscopic polyangiitis	0.767	0.233	0.000
J41 Simple and mucopurulent chronic bronchitis	0.766	0.234	0.000
M06.8 Other specified rheumatoid arthritis	0.763	0.237	0.000
H90-H95 Other disorders of ear	0.762	0.238	0.000
K57.4 Diverticular disease of both small and large intestine with perforation and abscess	0.762	0.238	0.000
J85 Abscess of lung and mediastinum	0.761	0.239	0.000
H91 Other hearing loss	0.758	0.242	0.000
E13 Other specified diabetes mellitus	0.757	0.243	0.000
E11.7 With multiple complications	0.757	0.243	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.757	0.243	0.000
H91.9 Hearing loss, unspecified	0.756	0.244	0.000
K72 Hepatic failure, not elsewhere classified	0.755	0.245	0.000
E16.1 Other hypoglycaemia	0.753	0.247	0.000
J99 Respiratory disorders in diseases classified elsewhere	0.753	0.247	0.000
E14.4 With neurological complications	0.752	0.248	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.752	0.248	0.000
E77 Disorders of glycoprotein metabolism	0.752	0.248	0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.751	0.249	0.000
J32.1 Chronic frontal sinusitis	0.751	0.249	0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.749	0.251	0.000
M25.43 Effusion of joint (Forearm)	0.748	0.252	0.000
H61.0 Perichondritis of external ear	0.747	0.253	0.000
M12 Other specific arthropathies	0.747	0.253	0.000
M60.0 Infective myositis	0.745	0.255	0.000
L40.5 Arthropathic psoriasis	0.744	0.256	0.000
L10-L14 Bullous disorders	0.743	0.257	0.000
J32.3 Chronic sphenoidal sinusitis	0.743	0.257	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.741	0.259	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.741	0.259	0.000
E74 Other disorders of carbohydrate metabolism	0.741	0.259	0.000
M25.9 Joint disorder, unspecified	0.738	0.262	0.000
M80-M85 Disorders of bone density and structure	0.738	0.262	0.000
E88.8 Other specified metabolic disorders	0.736	0.264	0.000
M34.9 Systemic sclerosis, unspecified	0.736	0.264	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.734	0.266	0.000
M65.86 Other synovitis and tenosynovitis (Lower leg)	0.732	0.268	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.731	0.269	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.730	0.270	0.000
K50 Crohn's disease [regional enteritis]	0.727	0.272	0.001
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.726	0.274	0.000
E78.6 Lipoprotein deficiency	0.724	0.276	0.000
E06.3 Autoimmune thyroiditis	0.722	0.278	0.000
M25.42 Effusion of joint (Upper arm)	0.722	0.278	0.000
E11.8 With unspecified complications	0.721	0.279	0.000
M31.9 Necrotising vasculopathy, unspecified	0.720	0.280	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.719	0.280	0.000
M86 Osteomyelitis	0.719	0.281	0.000
E73 Lactose intolerance	0.719	0.281	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.718	0.282	0.000
M88 Paget's disease of bone [osteitis deformans]	0.717	0.283	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.717	0.283	0.000
E14.7 With multiple complications	0.717	0.283	0.000
M06.2 Rheumatoid bursitis	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.717	0.283	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.717	0.283	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.717	0.283	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.717	0.283	0.000
M35.5 Multifocal fibrosclerosis	0.717	0.283	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.717	0.283	0.000
E03.5 Myxoedema coma	0.717	0.283	0.000
E03.4 Atrophy of thyroid (acquired)	0.717	0.283	0.000
E03.3 Postinfectious hypothyroidism	0.717	0.283	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.717	0.283	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.717	0.283	0.000
E16.4 Abnormal secretion of gastrin	0.717	0.283	0.000
E16.3 Increased secretion of glucagon	0.717	0.283	0.000
E15 Nondiabetic hypoglycaemic coma	0.717	0.283	0.000
M65.1 Other infective (teno)synovitis	0.717	0.283	0.000
E05.5 Thyroid crisis or storm	0.716	0.284	0.000
E05.4 Thyrotoxicosis factitia	0.716	0.284	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.716	0.284	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.716	0.284	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.716	0.284	0.000
M25.2 Flail joint	0.716	0.284	0.000
M25.1 Fistula of joint	0.716	0.284	0.000
E88.9 Metabolic disorder, unspecified	0.716	0.284	0.000
M25.49 Effusion of joint (Site unspecified)	0.715	0.285	0.000
M25.48 Effusion of joint (Other)	0.715	0.285	0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.714	0.286	0.000
K90.3 Pancreatic steatorrhoea	0.714	0.286	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.714	0.286	0.000
K90.1 Tropical sprue	0.714	0.286	0.000
E76 Disorders of glycosaminoglycan metabolism	0.714	0.286	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.714	0.286	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.714	0.286	0.000
K64 Haemorrhoids and perianal venous thrombosis	0.714	0.286	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.713	0.286	0.000
M31.2 Lethal midline granuloma	0.713	0.287	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.713	0.287	0.000
M05.0 Felty's syndrome	0.712	0.288	0.000
E11.6 With other specified complications	0.712	0.288	0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.711	0.289	0.000
M31.8 Other specified necrotising vasculopathies	0.710	0.290	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.708	0.292	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.708	0.292	0.000
M06.1 Adult-onset Still's disease	0.707	0.293	0.000
M25.41 Effusion of joint (Shoulder region)	0.706	0.294	0.000
M25.8 Other specified joint disorders	0.706	0.294	0.000
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess	0.706	0.294	0.000
K74.4 Secondary biliary cirrhosis	0.705	0.295	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.705	0.295	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.704	0.296	0.000
M06.38 Rheumatoid nodule (Other)	0.704	0.296	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.704	0.296	0.000
M06.33 Rheumatoid nodule (Forearm)	0.704	0.296	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.704	0.296	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.703	0.297	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.703	0.297	0.000
L40.9 Psoriasis, unspecified	0.701	0.299	0.000
M65.2 Calcific tendinitis	0.701	0.299	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.699	0.301	0.000
E72 Other disorders of amino-acid metabolism	0.698	0.302	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.698	0.302	0.000
K71 Toxic liver disease	0.697	0.303	0.000
J32.2 Chronic ethmoidal sinusitis	0.696	0.304	0.000
M65.0 Abscess of tendon sheath	0.696	0.304	0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.695	0.305	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.694	0.306	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.694	0.306	0.000
E07.9 Disorder of thyroid, unspecified	0.692	0.308	0.000
M66.5 Spontaneous rupture of unspecified tendon	0.692	0.308	0.000
J44.9 Chronic obstructive pulmonary disease, unspecified	0.692	0.308	0.000
E70 Disorders of aromatic amino-acid metabolism	0.690	0.310	0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.688	0.312	0.000
K75.2 Nonspecific reactive hepatitis	0.687	0.313	0.000
K75.1 Phlebitis of portal vein	0.687	0.313	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.687	0.313	0.000
E50-E64 Other nutritional deficiencies	0.687	0.313	0.000
E14.2 Withrenal complications	0.686	0.313	0.000
E89.5 Postprocedural testicular hypofunction	0.685	0.314	0.000
M34.0 Progressive systemic sclerosis	0.685	0.315	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.683	0.317	0.000
K60.3 Anal fistula	0.683	0.317	0.000
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec	0.682	0.317	0.000
M65.48 Radial styloid tenosynovitis [de Quervain]-Other	0.682	0.317	0.000
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot	0.682	0.317	0.000
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg	0.682	0.317	0.000
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh	0.682	0.317	0.000
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm	0.682	0.317	0.000
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region	0.682	0.317	0.000
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)	0.682	0.317	0.000
E89.1 Postprocedural hypoinsulinaemia	0.682	0.318	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.680	0.320	0.000
E45 Retarded development following protein-energy malnutrition	0.680	0.320	0.000
E43 Unspecified severe protein-energy malnutrition	0.680	0.320	0.000
E42 Marasmic kwashiorkor	0.680	0.320	0.000
E41 Nutritional marasmus	0.680	0.320	0.000
E40 Kwashiorkor	0.680	0.320	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.677	0.323	0.000
Chapter VI Diseases of the nervous system	0.677	0.323	0.000
K50.8 Other Crohn's disease	0.676	0.323	0.000
M25.3 Other instability of joint	0.677	0.323	0.000
M89 Other disorders of bone	0.675	0.324	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.003	0.324	0.672
M15.2 Bouchard's nodes (with arthropathy)	0.675	0.325	0.000
K57.5 Diverticular disease of both small and large intestine without perforation or abscess	0.674	0.326	0.000
L43.8 Other lichen planus	0.674	0.326	0.000
M24 Other specific joint derangements	0.672	0.328	0.000
J45.1 Nonallergic asthma	0.671	0.329	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.669	0.331	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.668	0.331	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.668	0.332	0.000
J37.0 Chronic laryngitis	0.667	0.333	0.000
J99.0 Rheumatoid lung disease	0.666	0.334	0.000
D55-D59 Haemolytic anaemias	0.662	0.334	0.004
M60.9 Myositis, unspecified	0.665	0.335	0.000
D62 Acute posthaemorrhagic anaemia	0.665	0.335	0.000
M60.05 Infective myositis (Pelvic region and thigh)	0.664	0.335	0.000
H80-H83 Diseases of inner ear	0.664	0.336	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.663	0.337	0.000
J45.0 Predominantly allergic asthma	0.662	0.338	0.000
L12 Pemphigoid	0.662	0.338	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.661	0.339	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.000	0.339	0.661
K50.1 Crohn's disease of large intestine	0.659	0.341	0.000
M11 Other crystal arthropathies	0.658	0.342	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.657	0.342	0.000
K77 Liver disorders in diseases classified elsewhere	0.656	0.344	0.000
K57.0 Diverticular disease of small intestine with perforation and abscess	0.655	0.345	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.655	0.345	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.655	0.345	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.654	0.346	0.000
M15.1 Heberden's nodes (with arthropathy)	0.654	0.346	0.000
J30 Vasomotor and allergic rhinitis	0.654	0.346	0.000
G70-G73 Diseases of myoneural junction and muscle	0.653	0.347	0.000
M67 Other disorders of synovium and tendon	0.653	0.347	0.000
M60.08 Infective myositis (Other)	0.653	0.347	0.000
H61.1 Non-infective disorders of pinna	0.650	0.350	0.000
G37.5 Concentric sclerosis [Balo]	0.004	0.350	0.646
G37.4 Subacute necrotising myelitis	0.004	0.350	0.646
G37.2 Central pontine myelinolysis	0.004	0.350	0.646
G37.1 Central demyelination of corpus callosum	0.004	0.350	0.646
G37.0 Diffuse sclerosis	0.004	0.350	0.646
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.649	0.351	0.000
M86.9 Osteomyelitis, unspecified	0.648	0.352	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.647	0.353	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.647	0.353	0.000
J99.1 Respiratory disorders in other diffuse connective tissue disorders	0.645	0.355	0.000
E78.3 Hyperchylomicronaemia	0.644	0.356	0.000
M25.45 Effusion of joint (Pelvic region and thigh)	0.644	0.356	0.000
M66.3 Spontaneous rupture of flexor tendons	0.644	0.356	0.000
G36 Other acute disseminated demyelination	0.016	0.358	0.626
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.640	0.360	0.000
M89.0 Algoneurodystrophy	0.640	0.360	0.000
M80 Osteoporosis with pathological fracture	0.640	0.360	0.000
M32 Systemic lupus erythematosus	0.639	0.361	0.000
M05.10 Rheumatoid lung disease (Multiple sites)	0.638	0.361	0.000
G70 Myasthenia gravis and other myoneural disorders	0.638	0.362	0.000
M10 Gout	0.637	0.363	0.000
K74.1 Hepatic sclerosis	0.636	0.364	0.000
M14.6 Neuropathic arthropathy	0.636	0.364	0.000
H61.8 Other specified disorders of external ear	0.636	0.364	0.000
L44 Other papulosquamous disorders	0.636	0.364	0.000
H60 Otitis externa	0.634	0.366	0.000
M05.2 Rheumatoid vasculitis	0.633	0.367	0.000
J45.8 Mixed asthma	0.632	0.367	0.000
M30 Polyarteritis nodosa and related conditions	0.632	0.368	0.000
E03.1 Congenital hypothyroidism without goitre	0.631	0.368	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.631	0.369	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.631	0.369	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.631	0.369	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.631	0.369	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.631	0.369	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.631	0.369	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.631	0.369	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.630	0.370	0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.630	0.370	0.000
G70.0 Myasthenia gravis	0.627	0.373	0.000
M35.0 Sicca syndrome [Sjogren]	0.627	0.373	0.000
E89.4 Postprocedural ovarian failure	0.625	0.375	0.000
G56.0 Carpal tunnel syndrome	0.625	0.375	0.000
K76 Other diseases of liver	0.625	0.375	0.000
M31.1 Thrombotic microangiopathy	0.624	0.376	0.000
E07.8 Other specified disorders of thyroid	0.623	0.377	0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.623	0.377	0.000
G56 Mononeuropathies of upper limb	0.621	0.379	0.000
M07 Psoriatic and enteropathic arthropathies	0.621	0.379	0.000
M08.0 Juvenile rheumatoid arthritis	0.620	0.380	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.620	0.380	0.000
K55 Vascular disorders of intestine	0.620	0.380	0.000
H91.1 Presbycusis	0.620	0.380	0.000
M88.9 Paget's disease of bone, unspecified	0.619	0.381	0.000
M25.0 Haemarthrosis	0.618	0.381	0.000
K90.9 Intestinal malabsorption, unspecified	0.618	0.382	0.000
E84 Cystic fibrosis	0.618	0.382	0.000
M25.7 Osteophyte	0.617	0.383	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.617	0.383	0.000
E03.8 Other specified hypothyroidism	0.616	0.383	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.616	0.384	0.000
M35.2 Behcet's disease	0.616	0.384	0.000
M14.2 Diabetic arthropathy	0.615	0.385	0.000
M05.19 Rheumatoid lung disease (Site unspecified)	0.615	0.385	0.000
M00-M03 Infectious arthropathies	0.613	0.387	0.000
M35.8 Other specified systemic involvement of connective tissue	0.613	0.387	0.000
M05.88 Other seropositive rheumatoid arthritis (Other)	0.611	0.389	0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.611	0.389	0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.611	0.389	0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.611	0.389	0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.611	0.389	0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.611	0.389	0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.611	0.389	0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.611	0.389	0.000
K60.4 Rectal fistula	0.610	0.390	0.000
J85.0 Gangrene and necrosis of lung	0.610	0.390	0.000
M82 Osteoporosis in diseases classified elsewhere	0.609	0.391	0.000
K76.8 Other specified diseases of liver	0.609	0.391	0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.608	0.392	0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.608	0.392	0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.608	0.392	0.000
L43.0 Hypertrophic lichen planus	0.607	0.393	0.000
Q80-Q89 Other congenital malformations	0.606	0.394	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.603	0.396	0.000
M61 Calcification and ossification of muscle	0.603	0.396	0.000
E88.2 Lipomatosis, not elsewhere classified	0.602	0.398	0.000
E05.8 Other thyrotoxicosis	0.602	0.398	0.000
M15.4 Erosive (osteo)arthrosis	0.602	0.398	0.000
M25.83 Other specified joint disorders (Forearm)	0.602	0.398	0.000
M24.5 Contracture of joint	0.602	0.398	0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.602	0.398	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.601	0.399	0.000
D64.0 Hereditary sideroblastic anaemia	0.600	0.400	0.000
J85.2 Abscess of lung without pneumonia	0.600	0.400	0.000
D64.3 Other sideroblastic anaemias	0.600	0.400	0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.599	0.401	0.000
J41.0 Simple chronic bronchitis	0.598	0.402	0.000
K61 Abscess of anal and rectal regions	0.598	0.402	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.597	0.403	0.000
L43.3 Subacute (active) lichen planus	0.596	0.404	0.000
L43.2 Lichenoid drug reaction	0.596	0.404	0.000
L43.1 Bullous lichen planus	0.596	0.404	0.000
L13 Other bullous disorders	0.596	0.404	0.000
E13.3 With ophthalmic complications	0.596	0.404	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations