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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74591415
log Bayes Factor = 13.4181
Chromosome 2   position 64,864,450  (GRCh37) Explore rs74591415 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
0.997 0.003 0.000
Chapter X Diseases of the respiratory system
0.994 0.006 0.000
Chapter II Neoplasms
0.993 0.007 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.992 0.008 0.000
K50-K52 Noninfective enteritis and colitis
0.992 0.008 0.000
Chapter I Certain infectious and parasitic diseases
0.987 0.013 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.986 0.014 0.000
K52 Other non-infective gastro-enteritis and colitis
0.984 0.016 0.000
Z93 Artificial opening status
0.983 0.017 0.000
Chapter V Mental and behavioural disorders
0.982 0.018 0.000
J30-J39 Other diseases of upper respiratory tract
0.980 0.020 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.979 0.021 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.975 0.025 0.000
O60-O75 Complications of labour and delivery
0.971 0.029 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.966 0.034 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.964 0.036 0.000
I30-I52 Other forms of heart disease
0.963 0.037 0.000
Chapter XX External causes of morbidity and mortality
0.962 0.038 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.962 0.038 0.000
K08 Other disorders of teeth and supporting structures
0.961 0.039 0.000
Z51 Other medical care
0.961 0.039 0.000
Chapter IX Diseases of the circulatory system
0.960 0.040 0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.949 0.051 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.945 0.055 0.000
K70-K77 Diseases of liver
0.943 0.057 0.000
J00-J06 Acute upper respiratory infections
0.942 0.058 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.941 0.059 0.000
C83.3 Large cell (diffuse)
0.940 0.060 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.936 0.064 0.000
I45 Other conduction disorders
0.932 0.068 0.000
Z85 Personal history of malignant neoplasm
0.930 0.070 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.927 0.073 0.000
Z93.2 Ileostomy status
0.926 0.074 0.000
S00-S09 Injuries to the head
0.926 0.074 0.000
B95-B98 Bacterial, viral and other infectious agents
0.924 0.076 0.000
Z92 Personal history of medical treatment
0.924 0.076 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.920 0.080 0.000
I46 Cardiac arrest
0.920 0.080 0.000
I45.1 Other and unspecified right bundle-branch block
0.916 0.084 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.915 0.085 0.000
S60-S69 Injuries to the wrist and hand
0.910 0.090 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.909 0.091 0.000
I49 Other cardiac arrhythmias
0.907 0.093 0.000
I51 Complications and ill-defined descriptions of heart disease
0.905 0.095 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.903 0.097 0.000
F41 Other anxiety disorders
0.899 0.101 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.899 0.101 0.000
C85.1 B-cell lymphoma, unspecified
0.895 0.105 0.000
Z98 Other postsurgical states
0.895 0.105 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.895 0.105 0.000
K08.3 Retained dental root
0.893 0.107 0.000
B35-B49 Mycoses
0.890 0.110 0.000
J34 Other disorders of nose and nasal sinuses
0.888 0.112 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.887 0.113 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.886 0.114 0.000
R06 Abnormalities of breathing
0.885 0.115 0.000
O70 Perineal laceration during delivery
0.884 0.116 0.000
R06.5 Mouth breathing
0.884 0.116 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.883 0.117 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.882 0.118 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.880 0.120 0.000
Z89 Acquired absence of limb
0.879 0.121 0.000
Z39 Postpartum care and examination
0.878 0.122 0.000
F60-F69 Disorders of adult personality and behaviour
0.878 0.122 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.878 0.122 0.000
Z94 Transplanted organ and tissue status
0.875 0.125 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.873 0.127 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.873 0.127 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.871 0.129 0.000
K08.8 Other specified disorders of teeth and supporting structures
0.868 0.132 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.867 0.133 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.866 0.134 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.865 0.135 0.000
F41.9 Anxiety disorder, unspecified
0.864 0.136 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.863 0.137 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.863 0.137 0.000
J02 Acute pharyngitis
0.863 0.137 0.000
S68 Traumatic amputation of wrist and hand
0.861 0.139 0.000
C15-C26 Malignant neoplasms of digestive organs
0.860 0.140 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.858 0.142 0.000
J90-J94 Other diseases of pleura
0.858 0.142 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.858 0.142 0.000
R06.0 Dyspnoea
0.849 0.151 0.000
K65-K67 Diseases of peritoneum
0.848 0.152 0.000
K76 Other diseases of liver
0.848 0.152 0.000
I46.9 Cardiac arrest, unspecified
0.846 0.154 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.843 0.157 0.000
S70-S79 Injuries to the hip and thigh
0.841 0.159 0.000
Z83 Family history of other specific disorders
0.841 0.159 0.000
Z40 Prophylactic surgery
0.837 0.163 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.837 0.163 0.000
K52.1 Toxic gastro-enteritis and colitis
0.835 0.165 0.000
K50 Crohn's disease [regional enteritis]
0.834 0.166 0.000
K04 Diseases of pulp and periapical tissues
0.830 0.170 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.829 0.171 0.000
K11 Diseases of salivary glands
0.829 0.171 0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)
0.826 0.174 0.000
Z92.3 Personal history of irradiation
0.825 0.175 0.000
B37 Candidiasis
0.822 0.178 0.000
Z43 Attention to artificial openings
0.819 0.181 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.819 0.181 0.000
J90 Pleural effusion, not elsewhere classified
0.818 0.182 0.000
K70 Alcoholic liver disease
0.818 0.182 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.817 0.183 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.815 0.184 0.000
Z39.1 Care and examination of lactating mother
0.813 0.187 0.000
D00-D09 In situ neoplasms
0.812 0.188 0.000
J09-J18 Influenza and pneumonia
0.812 0.188 0.000
T87 Complications peculiar to reattachment and amputation
0.812 0.188 0.000
I51.7 Cardiomegaly
0.811 0.189 0.000
I46.0 Cardiac arrest with successful resuscitation
0.811 0.189 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.811 0.189 0.000
Z34 Supervision of normal pregnancy
0.809 0.191 0.000
J39 Other diseases of upper respiratory tract
0.808 0.192 0.000
J38.7 Other diseases of larynx
0.807 0.193 0.000
J02.9 Acute pharyngitis, unspecified
0.806 0.194 0.000
A30-A49 Other bacterial diseases
0.806 0.194 0.000
F60 Specific personality disorders
0.803 0.197 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.803 0.197 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.799 0.201 0.000
I51.8 Other ill-defined heart diseases
0.798 0.202 0.000
Z51.5 Palliative care
0.798 0.202 0.000
Y43 Primarily systemic agents
0.798 0.202 0.000
B50-B64 Protozoal diseases
0.797 0.202 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.797 0.203 0.000
J35 Chronic diseases of tonsils and adenoids
0.797 0.203 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.794 0.206 0.000
Z37 Outcome of delivery
0.793 0.207 0.000
J33 Nasal polyp
0.792 0.208 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.792 0.208 0.000
K12 Stomatitis and related lesions
0.790 0.210 0.000
J04 Acute laryngitis and tracheitis
0.790 0.210 0.000
J30 Vasomotor and allergic rhinitis
0.789 0.211 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.789 0.211 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.789 0.211 0.000
R05 Cough
0.788 0.212 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.787 0.213 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.786 0.214 0.000
K00 Disorders of tooth development and eruption
0.786 0.214 0.000
I49.0 Ventricular fibrillation and flutter
0.783 0.217 0.000
Z93.3 Colostomy status
0.783 0.217 0.000
I49.9 Cardiac arrhythmia, unspecified
0.780 0.220 0.000
Z98.0 Intestinal bypass and anastomosis status
0.780 0.220 0.000
C64-C68 Malignant neoplasms of urinary tract
0.778 0.222 0.000
O69.1 Labour and delivery complicated by cord around neck, with compression
0.776 0.223 0.000
Z93.6 Other artificial openings of urinary tract status
0.776 0.224 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.776 0.224 0.000
I36 Nonrheumatic tricuspid valve disorders
0.775 0.225 0.000
I44 Atrioventricular and left bundle-branch block
0.775 0.225 0.000
O62 Abnormalities of forces of labour
0.774 0.226 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.774 0.226 0.000
S01 Open wound of head
0.773 0.227 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.773 0.227 0.000
S09 Other and unspecified injuries of head
0.773 0.227 0.000
S02 Fracture of skull and facial bones
0.773 0.227 0.000
O70.0 First degree perineal laceration during delivery
0.771 0.229 0.000
T93 Sequelae of injuries of lower limb
0.769 0.231 0.000
J95-J99 Other diseases of the respiratory system
0.769 0.231 0.000
K90-K93 Other diseases of the digestive system
0.769 0.231 0.000
Z51.8 Other specified medical care
0.768 0.232 0.000
K51 Ulcerative colitis
0.768 0.232 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.767 0.233 0.000
Z51.2 Other chemotherapy
0.766 0.234 0.000
O72 Postpartum haemorrhage
0.765 0.235 0.000
Z94.8 Other transplanted organ and tissue status
0.764 0.236 0.000
F80-F89 Disorders of psychological development
0.764 0.236 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.763 0.237 0.000
J34.2 Deviated nasal septum
0.763 0.237 0.000
Z45 Adjustment and management of implanted device
0.762 0.238 0.000
J38.0 Paralysis of vocal cords and larynx
0.762 0.238 0.000
I42 Cardiomyopathy
0.761 0.239 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.760 0.240 0.000
O48 Prolonged pregnancy
0.760 0.240 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.759 0.241 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.757 0.243 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.756 0.244 0.000
Z31 Procreative management
0.755 0.245 0.000
Z44 Fitting and adjustment of external prosthetic device
0.755 0.245 0.000
B37.0 Candidal stomatitis
0.754 0.246 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.751 0.249 0.000
K14 Diseases of tongue
0.750 0.250 0.000
Z93.1 Gastrostomy status
0.749 0.251 0.000
Chapter XXII Codes for special purposes
0.749 0.251 0.000
C78.2 Secondary malignant neoplasm of pleura
0.748 0.252 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.748 0.252 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.746 0.254 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.745 0.255 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.745 0.255 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.744 0.256 0.000
Y40 Systemic antibiotics
0.744 0.256 0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease
0.743 0.257 0.000
K07 Dentofacial anomalies [including malocclusion]
0.742 0.258 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.742 0.258 0.000
S80-S89 Injuries to the knee and lower leg
0.742 0.258 0.000
Z82.3 Family history of stroke
0.741 0.259 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.741 0.259 0.000
J03 Acute tonsillitis
0.740 0.260 0.000
Z51.1 Chemotherapy session for neoplasm
0.740 0.260 0.000
Z91.6 Personal history of other physical trauma
0.738 0.262 0.000
C90.0 Multiple myeloma
0.737 0.263 0.000
O42 Premature rupture of membranes
0.737 0.263 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.736 0.264 0.000
S61 Open wound of wrist and hand
0.734 0.266 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.734 0.266 0.000
Y44 Agents primarily affecting blood constituents
0.733 0.267 0.000
J33.8 Other polyp of sinus
0.732 0.268 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.730 0.270 0.000
Z35 Supervision of high-risk pregnancy
0.729 0.271 0.000
J38.4 Oedema of larynx
0.728 0.272 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.726 0.274 0.000
A80-A89 Viral infections of the central nervous system
0.726 0.274 0.000
C25 Malignant neoplasm of pancreas
0.725 0.275 0.000
Z98.8 Other specified postsurgical states
0.724 0.276 0.000
O66 Other obstructed labour
0.724 0.276 0.000
F41.2 Mixed anxiety and depressive disorder
0.724 0.276 0.000
F60.9 Personality disorder, unspecified
0.723 0.277 0.000
Z37.0 Single live birth
0.722 0.278 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.721 0.279 0.000
Z80 Family history of malignant neoplasm
0.720 0.280 0.000
S05 Injury of eye and orbit
0.719 0.281 0.000
K13 Other diseases of lip and oral mucosa
0.719 0.281 0.000
C51-C58 Malignant neoplasms of female genital organs
0.719 0.281 0.000
I49.5 Sick sinus syndrome
0.718 0.282 0.000
A00-A09 Intestinal infectious diseases
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.717 0.283 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.716 0.283 0.000
S72 Fracture of femur
0.716 0.284 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.716 0.284 0.000
O47 False labour
0.713 0.286 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.713 0.287 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.713 0.287 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.712 0.288 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.712 0.288 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.712 0.288 0.000
Z89.6 Acquired absence of leg above knee
0.712 0.288 0.000
T79-T79 Certain early complications of trauma
0.712 0.288 0.000
F30-F39 Mood [affective] disorders
0.712 0.288 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.712 0.288 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.711 0.289 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.711 0.289 0.000
C95 Leukaemia of unspecified cell type
0.711 0.289 0.000
C94 Other leukaemias of specified cell type
0.711 0.289 0.000
C93 Monocytic leukaemia
0.711 0.289 0.000
C88 Malignant immunoproliferative diseases
0.711 0.289 0.000
C86 Other specified types of T/NK-cell lymphoma
0.711 0.289 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.711 0.289 0.000
C81 Hodgkin's disease
0.711 0.289 0.000
S64 Injury of nerves at wrist and hand level
0.711 0.289 0.000
K72 Hepatic failure, not elsewhere classified
0.711 0.289 0.000
Y43.3 Other antineoplastic drugs
0.710 0.290 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.710 0.290 0.000
S90-S99 Injuries to the ankle and foot
0.710 0.290 0.000
I33 Acute and subacute endocarditis
0.708 0.292 0.000
B99-B99 Other infectious diseases
0.707 0.293 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.707 0.293 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.707 0.293 0.000
B65-B83 Helminthiases
0.707 0.293 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.707 0.293 0.000
B15-B19 Viral hepatitis
0.707 0.293 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.707 0.293 0.000
A75-A79 Rickettsioses
0.707 0.293 0.000
A70-A74 Other diseases caused by chlamydiae
0.707 0.293 0.000
A65-A69 Other spirochaetal diseases
0.707 0.293 0.000
A20-A28 Certain zoonotic bacterial diseases
0.707 0.293 0.000
A15-A19 Tuberculosis
0.707 0.293 0.000
K10 Other diseases of jaws
0.707 0.293 0.000
K03 Other diseases of hard tissues of teeth
0.707 0.293 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.707 0.293 0.000
Z39.0 Care and examination immediately after delivery
0.706 0.294 0.000
C92 Myeloid leukaemia
0.706 0.294 0.000
F40 Phobic anxiety disorders
0.706 0.294 0.000
Z49 Care involving dialysis
0.706 0.294 0.000
F43 Reaction to severe stress, and adjustment disorders
0.706 0.294 0.000
K52.3 Indeterminate colitis
0.705 0.295 0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.705 0.295 0.000
K52.0 Gastro-enteritis and colitis due to radiation
0.705 0.295 0.000
Z93.9 Artificial opening status, unspecified
0.705 0.295 0.000
Z93.8 Other artificial opening status
0.705 0.295 0.000
R47-R49 Symptoms and signs involving speech and voice
0.705 0.295 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.704 0.296 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.704 0.296 0.000
F70-F79 Mental retardation
0.704 0.296 0.000
K50.1 Crohn's disease of large intestine
0.704 0.296 0.000
V80-V89 Other land transport accidents
0.704 0.296 0.000
Z94.7 Corneal transplant status
0.703 0.296 0.000
F42 Obsessive-compulsive disorder
0.703 0.297 0.000
J37 Chronic laryngitis and laryngotracheitis
0.703 0.297 0.000
K09 Cysts of oral region, not elsewhere classified
0.703 0.297 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.702 0.298 0.000
Z51.3 Blood transfusion without reported diagnosis
0.702 0.298 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.702 0.298 0.000
O85-O92 Complications predominantly related to the puerperium
0.702 0.298 0.000
Z89.5 Acquired absence of leg at or below knee
0.701 0.299 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.700 0.300 0.000
Z83.4 Family history of other endocrine, nutritional and metabolic diseases
0.700 0.300 0.000
J60-J70 Lung diseases due to external agents
0.700 0.300 0.000
O70.2 Third degree perineal laceration during delivery
0.699 0.301 0.000
T86 Failure and rejection of transplanted organs and tissues
0.699 0.301 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.699 0.301 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.698 0.301 0.000
I47 Paroxysmal tachycardia
0.698 0.301 0.000
Z89.4 Acquired absence of foot and ankle
0.698 0.302 0.000
J00 Acute nasopharyngitis [common cold]
0.697 0.303 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.697 0.303 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.697 0.303 0.000
T66-T78 Other and unspecified effects of external causes
0.697 0.303 0.000
O70.1 Second degree perineal laceration during delivery
0.696 0.304 0.000
O74 Complications of anaesthesia during labour and delivery
0.696 0.304 0.000
O73 Retained placenta and membranes, without haemorrhage
0.696 0.304 0.000
O71 Other obstetric trauma
0.696 0.304 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.696 0.304 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.696 0.304 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.696 0.304 0.000
O61 Failed induction of labour
0.696 0.304 0.000
O60 Preterm delivery
0.696 0.304 0.000
T87.6 Other and unspecified complications of amputation stump
0.695 0.305 0.000
V10-V19 Pedal cyclist injured in transport accident
0.693 0.306 0.000
Z93.5 Cystostomy status
0.693 0.307 0.000
Z52 Donors of organs and tissues
0.693 0.307 0.000
Z54 Convalescence
0.692 0.307 0.000
K66 Other disorders of peritoneum
0.692 0.308 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.692 0.308 0.000
T91 Sequelae of injuries of neck and trunk
0.692 0.308 0.000
J36 Peritonsillar abscess
0.692 0.308 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.691 0.308 0.000
B37.3 Candidiasis of vulva and vagina
0.691 0.309 0.000
I30 Acute pericarditis
0.691 0.309 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.691 0.309 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.691 0.309 0.000
C85.0 Lymphosarcoma
0.691 0.309 0.000
R06.2 Wheezing
0.691 0.309 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.691 0.309 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.691 0.309 0.000
I52 Other heart disorders in diseases classified elsewhere
0.690 0.310 0.000
I48 Atrial fibrillation and flutter
0.690 0.310 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.690 0.310 0.000
I41 Myocarditis in diseases classified elsewhere
0.690 0.310 0.000
I40 Acute myocarditis
0.690 0.310 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.690 0.310 0.000
I37 Pulmonary valve disorders
0.690 0.310 0.000
I32 Pericarditis in diseases classified elsewhere
0.690 0.310 0.000
X60-X84 Intentional self-harm
0.690 0.310 0.000
I49.1 Atrial premature depolarisation
0.690 0.310 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.690 0.310 0.000
Y35-Y36 Legal intervention and operations of war
0.690 0.310 0.000
Y10-Y34 Event of undetermined intent
0.690 0.310 0.000
Y00-Y09 Assault
0.690 0.310 0.000
X85-X99 Assault
0.690 0.310 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.690 0.310 0.000
X50-X57 Overexertion, travel and privation
0.690 0.310 0.000
X30-X39 Exposure to forces of nature
0.690 0.310 0.000
X20-X29 Contact with venomous animals and plants
0.690 0.310 0.000
X10-X19 Contact with heat and hot substances
0.690 0.310 0.000
X00-X09 Exposure to smoke, fire and flames
0.690 0.310 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.690 0.310 0.000
W75-W84 Other accidental threats to breathing
0.690 0.310 0.000
W65-W74 Accidental drowning and submersion
0.690 0.310 0.000
W50-W64 Exposure to animate mechanical forces
0.690 0.310 0.000
V98-V99 Other and unspecified transport accidents
0.690 0.310 0.000
V95-V97 Air and space transport accidents
0.690 0.310 0.000
V90-V94 Water transport accidents
0.690 0.310 0.000
V70-V79 Bus occupant injured in transport accident
0.690 0.310 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.690 0.310 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.690 0.310 0.000
V40-V49 Car occupant injured in transport accident
0.690 0.310 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.690 0.310 0.000
V20-V29 Motorcycle rider injured in transport accident
0.690 0.310 0.000
V01-V09 Pedestrian injured in transport accident
0.690 0.310 0.000
I31 Other diseases of pericardium
0.690 0.310 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.689 0.311 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.689 0.311 0.000
C83.7 Burkitt's tumour
0.689 0.311 0.000
C83.6 Undifferentiated (diffuse)
0.689 0.311 0.000
C83.5 Lymphoblastic (diffuse)
0.689 0.311 0.000
C83.4 Immunoblastic (diffuse)
0.689 0.311 0.000
C83.2 Mixed small and large cell (diffuse)
0.689 0.311 0.000
C83.1 Small cleaved cell (diffuse)
0.689 0.311 0.000
C83.0 Small cell (diffuse)
0.689 0.311 0.000
I49.4 Other and unspecified premature depolarisation
0.689 0.311 0.000
K08.9 Disorder of teeth and supporting structures, unspecified
0.689 0.311 0.000
K08.2 Atrophy of edentulous alveolar ridge
0.689 0.311 0.000
K08.0 Exfoliation of teeth due to systemic causes
0.689 0.311 0.000
Z51.9 Medical care, unspecified
0.689 0.311 0.000
Z51.6 Desensitisation to allergens
0.689 0.311 0.000
I00-I02 Acute rheumatic fever
0.688 0.312 0.000
K75 Other inflammatory liver diseases
0.688 0.312 0.000
W00-W19 Falls
0.687 0.313 0.000
I20-I25 Ischaemic heart diseases
0.685 0.315 0.000
J39.2 Other diseases of pharynx
0.685 0.315 0.000
K65 Peritonitis
0.684 0.315 0.000
I49.8 Other specified cardiac arrhythmias
0.684 0.316 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.682 0.318 0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues
0.682 0.318 0.000
S50-S59 Injuries to the elbow and forearm
0.681 0.319 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.681 0.319 0.000
J04.0 Acute laryngitis
0.680 0.320 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.680 0.320 0.000
Y86 Sequelae of other accidents
0.680 0.320 0.000
T82.3 Mechanical complication of other vascular grafts
0.679 0.321 0.000
S06 Intracranial injury
0.678 0.322 0.000
Z91.5 Personal history of self-harm
0.678 0.322 0.000
K04.5 Chronic apical periodontitis
0.678 0.322 0.000
K11.2 Sialoadenitis
0.677 0.323 0.000
O36 Maternal care for other known or suspected foetal problems
0.677 0.323 0.000
Z93.0 Tracheostomy status
0.677 0.323 0.000
K77 Liver disorders in diseases classified elsewhere
0.676 0.324 0.000
K73 Chronic hepatitis, not elsewhere classified
0.676 0.324 0.000
K71 Toxic liver disease
0.676 0.324 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.676 0.324 0.000
J01 Acute sinusitis
0.676 0.324 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.676 0.324 0.000
I44.0 Atrioventricular block, first degree
0.675 0.325 0.000
Z38 Liveborn infants according to place of birth
0.674 0.325 0.000
Z32 Pregnancy examination and test
0.674 0.325 0.000
Z51.0 Radiotherapy session
0.674 0.325 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.673 0.327 0.000
Y42.7 Androgens and anabolic congeners
0.673 0.327 0.000
F99-F99 Unspecified mental disorder
0.673 0.327 0.000
Z95.0 Presence of cardiac pacemaker
0.673 0.327 0.000
Z43.3 Attention to colostomy
0.672 0.328 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.672 0.328 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.672 0.328 0.000
F48 Other neurotic disorders
0.671 0.329 0.000
F44 Dissociative [conversion] disorders
0.671 0.329 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.670 0.329 0.000
D03 Melanoma in situ
0.670 0.330 0.000
I45.8 Other specified conduction disorders
0.668 0.331 0.000
I45.5 Other specified heart block
0.668 0.331 0.000
I45.4 Nonspecific intraventricular block
0.668 0.331 0.000
I45.3 Trifascicular block
0.668 0.331 0.000
I45.2 Bifascicular block
0.668 0.331 0.000
I45.0 Right fascicular block
0.668 0.331 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.667 0.333 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.667 0.333 0.000
Z85.6 Personal history of leukaemia
0.666 0.334 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.666 0.334 0.000
Z91.8 Personal history of other specified risk-factors, not elsewhere classified
0.665 0.335 0.000
Z91.7 Personal history of female genital mutilation
0.665 0.335 0.000
Z91.4 Personal history of psychological trauma, not elsewhere classified
0.665 0.335 0.000
Z91.3 Personal history of unhealthy sleep-wake schedule
0.665 0.335 0.000
Z91.2 Personal history of poor personal hygiene
0.665 0.335 0.000
K74 Fibrosis and cirrhosis of liver
0.664 0.336 0.000
S08 Traumatic amputation of part of head
0.664 0.336 0.000
S07 Crushing injury of head
0.664 0.336 0.000
S04 Injury of cranial nerves
0.664 0.336 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.664 0.336 0.000
T93.2 Sequelae of other fractures of lower limb
0.664 0.336 0.000
S20-S29 Injuries to the thorax
0.664 0.336 0.000
Z90.1 Acquired absence of breast(s)
0.664 0.336 0.000
S60 Superficial injury of wrist and hand
0.663 0.336 0.000
S09.9 Unspecified injury of head
0.663 0.337 0.000
K04.6 Periapical abscess with sinus
0.663 0.337 0.000
S02.5 Fracture of tooth
0.662 0.337 0.000
Z36 Antenatal screening
0.662 0.338 0.000
Z92.9 Personal history of medical treatment, unspecified
0.662 0.338 0.000
Z92.8 Personal history of other medical treatment
0.662 0.338 0.000
Z92.5 Personal history of rehabilitation measures
0.662 0.338 0.000
Z92.0 Personal history of contraception
0.662 0.338 0.000
B59 Pneumocystosis
0.662 0.338 0.000
Z83.3 Family history of diabetes mellitus
0.662 0.338 0.000
K02 Dental caries
0.661 0.339 0.000
I44.2 Atrioventricular block, complete
0.661 0.339 0.000
Y59 Other and unspecified vaccines and biological substances
0.660 0.340 0.000
Y58 Bacterial vaccines
0.660 0.340 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.660 0.340 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.660 0.340 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.660 0.340 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.660 0.340 0.000
Y52 Agents primarily affecting the cardiovascular system
0.660 0.340 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.660 0.340 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.660 0.340 0.000
Y48 Anaesthetics and therapeutic gases
0.660 0.340 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.660 0.340 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.660 0.340 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.660 0.340 0.000
I46.1 Sudden cardiac death, so described
0.659 0.340 0.000
T88.4 Failed or difficult intubation
0.659 0.341 0.000
K70.0 Alcoholic fatty liver
0.659 0.341 0.000
T92 Sequelae of injuries of upper limb
0.658 0.342 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.656 0.344 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.656 0.344 0.000
Z43.4 Attention to other artificial openings of digestive tract
0.656 0.344 0.000
Z95.2 Presence of prosthetic heart valve
0.655 0.345 0.000
A41 Other septicaemia
0.654 0.346 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.654 0.346 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.654 0.346 0.000
K70.3 Alcoholic cirrhosis of liver
0.653 0.346 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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