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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74818966
log Bayes Factor = 15.4722
Chromosome 5   position 37,985,073  (GRCh37) Explore rs74818966 on Ensembl!
Variant rs74818966 is part of Cluster X0039

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
I25 Chronic ischaemic heart disease
0.998 0.002 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
E10-E14 Diabetes mellitus
0.993 0.007 0.000
Chapter I Certain infectious and parasitic diseases
0.987 0.013 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.987 0.013 0.000
I30-I52 Other forms of heart disease
0.985 0.015 0.000
Chapter XIV Diseases of the genitourinary system
0.984 0.016 0.000
Chapter XXI Factors influencing health status and contact with health services
0.983 0.017 0.000
I25.2 Old myocardial infarction
0.981 0.019 0.000
E10 Insulin-dependent diabetes mellitus
0.976 0.024 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.973 0.027 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.972 0.028 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.971 0.029 0.000
E70-E90 Metabolic disorders
0.971 0.029 0.000
I60-I69 Cerebrovascular diseases
0.967 0.033 0.000
R10 Abdominal and pelvic pain
0.964 0.036 0.000
Chapter XX External causes of morbidity and mortality
0.964 0.036 0.000
I20 Angina pectoris
0.959 0.041 0.000
I50 Heart failure
0.957 0.043 0.000
N17-N19 Renal failure
0.955 0.045 0.000
Z51 Other medical care
0.953 0.047 0.000
Chapter VI Diseases of the nervous system
0.950 0.050 0.000
B95-B98 Bacterial, viral and other infectious agents
0.945 0.055 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.943 0.057 0.000
N18 Chronic renal failure
0.937 0.063 0.000
E83 Disorders of mineral metabolism
0.926 0.074 0.000
R10.3 Pain localised to other parts of lower abdomen
0.919 0.081 0.000
E10.9 Without complications
0.918 0.082 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.915 0.085 0.000
S50-S59 Injuries to the elbow and forearm
0.914 0.086 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.912 0.088 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.911 0.089 0.000
Z51.3 Blood transfusion without reported diagnosis
0.910 0.090 0.000
N60-N64 Disorders of breast
0.910 0.090 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.907 0.093 0.000
I50.1 Left ventricular failure
0.899 0.101 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.894 0.106 0.000
I69 Sequelae of cerebrovascular disease
0.893 0.107 0.000
N18.3 Chronic kidney disease, stage 3
0.887 0.113 0.000
N10-N16 Renal tubulo-interstitial diseases
0.887 0.113 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.886 0.114 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.885 0.115 0.000
Z47 Other orthopaedic follow-up care
0.880 0.120 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.879 0.121 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.875 0.125 0.000
R10.2 Pelvic and perineal pain
0.873 0.127 0.000
E14 Unspecified diabetes mellitus
0.869 0.131 0.000
I20.0 Unstable angina
0.868 0.132 0.000
N00-N08 Glomerular diseases
0.866 0.134 0.000
Chapter VIII Diseases of the ear and mastoid process
0.864 0.136 0.000
E83.5 Disorders of calcium metabolism
0.863 0.137 0.000
N18.9 Chronic renal failure, unspecified
0.862 0.138 0.000
S00-S09 Injuries to the head
0.859 0.141 0.000
M65-M68 Disorders of synovium and tendon
0.858 0.142 0.000
Z51.5 Palliative care
0.857 0.143 0.000
I67 Other cerebrovascular diseases
0.857 0.143 0.000
Chapter XXII Codes for special purposes
0.857 0.143 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.855 0.145 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.855 0.145 0.000
M45-M49 Spondylopathies
0.855 0.145 0.000
E10.3 With ophthalmic complications
0.854 0.146 0.000
W00-W19 Falls
0.848 0.152 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.847 0.153 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.842 0.158 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.838 0.162 0.000
Chapter X Diseases of the respiratory system
0.838 0.162 0.000
S60-S69 Injuries to the wrist and hand
0.835 0.165 0.000
Chapter II Neoplasms
0.832 0.168 0.000
I20.8 Other forms of angina pectoris
0.832 0.168 0.000
I42 Cardiomyopathy
0.832 0.168 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.830 0.170 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.829 0.171 0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.824 0.176 0.000
E11 Non-insulin-dependent diabetes mellitus
0.823 0.177 0.000
I63 Cerebral infarction
0.822 0.178 0.000
I50.0 Congestive heart failure
0.820 0.180 0.000
R13 Dysphagia
0.817 0.183 0.000
Z22 Carrier of infectious disease
0.816 0.184 0.000
N13 Obstructive and reflux uropathy
0.816 0.184 0.000
R04 Haemorrhage from respiratory passages
0.815 0.185 0.000
S52 Fracture of forearm
0.814 0.186 0.000
R12 Heartburn
0.814 0.186 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.810 0.190 0.000
R10.1 Pain localised to upper abdomen
0.810 0.190 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.810 0.190 0.000
Chapter V Mental and behavioural disorders
0.809 0.191 0.000
A00-A09 Intestinal infectious diseases
0.807 0.193 0.000
I67.9 Cerebrovascular disease, unspecified
0.804 0.196 0.000
Z51.0 Radiotherapy session
0.803 0.197 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.802 0.198 0.000
S80-S89 Injuries to the knee and lower leg
0.802 0.198 0.000
R11 Nausea and vomiting
0.801 0.199 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.800 0.200 0.000
E10.2 With renal complications
0.800 0.200 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.798 0.201 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.797 0.203 0.000
Chapter VII Diseases of the eye and adnexa
0.797 0.203 0.000
G90-G99 Other disorders of the nervous system
0.795 0.205 0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons
0.794 0.206 0.000
E14.9 Without complications
0.793 0.207 0.000
M50-M54 Other dorsopathies
0.792 0.208 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.792 0.208 0.000
B35-B49 Mycoses
0.791 0.209 0.000
G81 Hemiplegia
0.790 0.210 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.790 0.210 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.789 0.210 0.000
Z51.1 Chemotherapy session for neoplasm
0.789 0.211 0.000
E74 Other disorders of carbohydrate metabolism
0.789 0.211 0.000
E50-E64 Other nutritional deficiencies
0.787 0.213 0.000
H65-H75 Diseases of middle ear and mastoid
0.787 0.213 0.000
I49 Other cardiac arrhythmias
0.786 0.214 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.785 0.215 0.000
E10.5 With peripheral circulatory complications
0.784 0.215 0.000
S90-S99 Injuries to the ankle and foot
0.783 0.217 0.000
N20-N23 Urolithiasis
0.783 0.217 0.000
A30-A49 Other bacterial diseases
0.782 0.218 0.000
J00-J06 Acute upper respiratory infections
0.782 0.218 0.000
I38 Endocarditis, valve unspecified
0.781 0.218 0.000
E83.1 Disorders of iron metabolism
0.781 0.219 0.000
N62 Hypertrophy of breast
0.780 0.220 0.000
E87.5 Hyperkalaemia
0.779 0.221 0.000
E40-E46 Malnutrition
0.778 0.222 0.000
C51-C58 Malignant neoplasms of female genital organs
0.777 0.223 0.000
I05-I09 Chronic rheumatic heart diseases
0.777 0.223 0.000
I50.9 Heart failure, unspecified
0.777 0.223 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.777 0.223 0.000
E87.6 Hypokalaemia
0.777 0.223 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.775 0.225 0.000
I47 Paroxysmal tachycardia
0.775 0.225 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.774 0.226 0.000
S40-S49 Injuries to the shoulder and upper arm
0.774 0.226 0.000
I25.5 Ischaemic cardiomyopathy
0.774 0.226 0.000
S10-S19 Injuries to the neck
0.774 0.226 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.773 0.227 0.000
M67 Other disorders of synovium and tendon
0.772 0.228 0.000
V20-V29 Motorcycle rider injured in transport accident
0.767 0.233 0.000
Z22.3 Carrier of other specified bacterial diseases
0.767 0.233 0.000
R04.2 Haemoptysis
0.767 0.233 0.000
S20-S29 Injuries to the thorax
0.764 0.236 0.000
I30 Acute pericarditis
0.763 0.237 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.763 0.237 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.762 0.238 0.000
I22 Subsequent myocardial infarction
0.760 0.240 0.000
L40-L45 Papulosquamous disorders
0.759 0.241 0.000
Y43 Primarily systemic agents
0.758 0.242 0.000
N63 Unspecified lump in breast
0.753 0.246 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.753 0.247 0.000
N60 Benign mammary dysplasia
0.751 0.249 0.000
I62 Other nontraumatic intracranial haemorrhage
0.750 0.250 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.749 0.251 0.000
I20.9 Angina pectoris, unspecified
0.748 0.252 0.000
I44 Atrioventricular and left bundle-branch block
0.747 0.252 0.000
W19 Unspecified fall
0.747 0.253 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.747 0.253 0.000
Z51.8 Other specified medical care
0.746 0.254 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.745 0.255 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.745 0.255 0.000
G40-G47 Episodic and paroxysmal disorders
0.741 0.259 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.740 0.259 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.735 0.265 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.735 0.265 0.000
R10.0 Acute abdomen
0.732 0.268 0.000
N03 Chronic nephritic syndrome
0.731 0.269 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.730 0.269 0.000
G81.9 Hemiplegia, unspecified
0.730 0.270 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.730 0.270 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.728 0.271 0.000
I31 Other diseases of pericardium
0.727 0.273 0.000
M70-M79 Other soft tissue disorders
0.726 0.273 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.726 0.274 0.000
B25-B34 Other viral diseases
0.726 0.274 0.000
I45 Other conduction disorders
0.725 0.275 0.000
S50 Superficial injury of forearm
0.724 0.276 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.724 0.276 0.000
T66-T78 Other and unspecified effects of external causes
0.724 0.276 0.000
I20.1 Angina pectoris with documented spasm
0.723 0.277 0.000
Z50 Care involving use of rehabilitation procedures
0.723 0.277 0.000
S32 Fracture of lumbar spine and pelvis
0.722 0.278 0.000
S01 Open wound of head
0.722 0.278 0.000
N17 Acute renal failure
0.721 0.279 0.000
R10.4 Other and unspecified abdominal pain
0.720 0.280 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.720 0.280 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.720 0.280 0.000
I60 Subarachnoid haemorrhage
0.720 0.280 0.000
Z53.9 Procedure not carried out, unspecified reason
0.719 0.280 0.000
Z40 Prophylactic surgery
0.719 0.281 0.000
D69 Purpura and other haemorrhagic conditions
0.719 0.281 0.000
M48 Other spondylopathies
0.719 0.281 0.000
S70-S79 Injuries to the hip and thigh
0.719 0.281 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.718 0.282 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.718 0.282 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.716 0.284 0.000
I25.4 Coronary artery aneurysm
0.716 0.284 0.000
I25.3 Aneurysm of heart
0.716 0.284 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.716 0.284 0.000
T79-T79 Certain early complications of trauma
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
S52.6 Fracture of lower end of both ulna and radius
0.715 0.284 0.000
D60-D64 Aplastic and other anaemias
0.713 0.287 0.000
E13 Other specified diabetes mellitus
0.712 0.288 0.000
E12 Malnutrition-related diabetes mellitus
0.712 0.288 0.000
W20-W49 Exposure to inanimate mechanical forces
0.712 0.288 0.000
Z43 Attention to artificial openings
0.712 0.288 0.000
E65-E68 Obesity and other hyperalimentation
0.712 0.288 0.000
Y44 Agents primarily affecting blood constituents
0.712 0.288 0.000
S02 Fracture of skull and facial bones
0.711 0.289 0.000
E11.4 With neurological complications
0.711 0.289 0.000
J02 Acute pharyngitis
0.710 0.290 0.000
M67.8 Other specified disorders of synovium and tendon
0.710 0.290 0.000
Z30 Contraceptive management
0.709 0.291 0.000
J90-J94 Other diseases of pleura
0.708 0.292 0.000
B99-B99 Other infectious diseases
0.708 0.292 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.708 0.292 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.708 0.292 0.000
B65-B83 Helminthiases
0.708 0.292 0.000
B50-B64 Protozoal diseases
0.708 0.292 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.708 0.292 0.000
B15-B19 Viral hepatitis
0.708 0.292 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.708 0.292 0.000
A80-A89 Viral infections of the central nervous system
0.708 0.292 0.000
A75-A79 Rickettsioses
0.708 0.292 0.000
A70-A74 Other diseases caused by chlamydiae
0.708 0.292 0.000
A65-A69 Other spirochaetal diseases
0.708 0.292 0.000
A20-A28 Certain zoonotic bacterial diseases
0.708 0.292 0.000
A15-A19 Tuberculosis
0.708 0.292 0.000
Z49 Care involving dialysis
0.708 0.292 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.708 0.292 0.000
L20-L30 Dermatitis and eczema
0.706 0.294 0.000
I52 Other heart disorders in diseases classified elsewhere
0.706 0.294 0.000
I48 Atrial fibrillation and flutter
0.706 0.294 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.706 0.294 0.000
I41 Myocarditis in diseases classified elsewhere
0.706 0.294 0.000
I40 Acute myocarditis
0.706 0.294 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.706 0.294 0.000
I37 Pulmonary valve disorders
0.706 0.294 0.000
I36 Nonrheumatic tricuspid valve disorders
0.706 0.294 0.000
I33 Acute and subacute endocarditis
0.706 0.294 0.000
I32 Pericarditis in diseases classified elsewhere
0.706 0.294 0.000
M45 Ankylosing spondylitis
0.705 0.295 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.704 0.296 0.000
R04.0 Epistaxis
0.704 0.296 0.000
X60-X84 Intentional self-harm
0.704 0.296 0.000
N21 Calculus of lower urinary tract
0.704 0.296 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.703 0.297 0.000
E88 Other metabolic disorders
0.703 0.297 0.000
L08 Other local infections of skin and subcutaneous tissue
0.703 0.297 0.000
S51 Open wound of forearm
0.702 0.298 0.000
A04 Other bacterial intestinal infections
0.702 0.298 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.702 0.298 0.000
N18.5 Chronic kidney disease, stage 5
0.702 0.298 0.000
E10.8 With unspecified complications
0.700 0.300 0.000
E10.7 With multiple complications
0.700 0.300 0.000
E10.6 With other specified complications
0.700 0.300 0.000
E10.4 With neurological complications
0.700 0.300 0.000
E10.0 With coma
0.700 0.300 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.698 0.301 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.697 0.303 0.000
Z54 Convalescence
0.697 0.303 0.000
Z52 Donors of organs and tissues
0.697 0.303 0.000
Z44 Fitting and adjustment of external prosthetic device
0.697 0.303 0.000
I46 Cardiac arrest
0.696 0.304 0.000
E85 Amyloidosis
0.696 0.304 0.000
E84 Cystic fibrosis
0.696 0.304 0.000
E79 Disorders of purine and pyrimidine metabolism
0.696 0.304 0.000
E77 Disorders of glycoprotein metabolism
0.696 0.304 0.000
E76 Disorders of glycosaminoglycan metabolism
0.696 0.304 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.696 0.304 0.000
E73 Lactose intolerance
0.696 0.304 0.000
E72 Other disorders of amino-acid metabolism
0.696 0.304 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.696 0.304 0.000
E70 Disorders of aromatic amino-acid metabolism
0.696 0.304 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.696 0.304 0.000
N18.0 End-stage renal disease
0.696 0.304 0.000
I63.9 Cerebral infarction, unspecified
0.696 0.304 0.000
N99-N99 Other disorders of the genitourinary system
0.695 0.304 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.694 0.306 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.693 0.307 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.693 0.307 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.692 0.308 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.691 0.309 0.000
Y35-Y36 Legal intervention and operations of war
0.691 0.309 0.000
Y10-Y34 Event of undetermined intent
0.691 0.309 0.000
Y00-Y09 Assault
0.691 0.309 0.000
X85-X99 Assault
0.691 0.309 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.691 0.309 0.000
X50-X57 Overexertion, travel and privation
0.691 0.309 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.691 0.309 0.000
X30-X39 Exposure to forces of nature
0.691 0.309 0.000
X20-X29 Contact with venomous animals and plants
0.691 0.309 0.000
X10-X19 Contact with heat and hot substances
0.691 0.309 0.000
X00-X09 Exposure to smoke, fire and flames
0.691 0.309 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.691 0.309 0.000
W75-W84 Other accidental threats to breathing
0.691 0.309 0.000
W65-W74 Accidental drowning and submersion
0.691 0.309 0.000
W50-W64 Exposure to animate mechanical forces
0.691 0.309 0.000
V98-V99 Other and unspecified transport accidents
0.691 0.309 0.000
V95-V97 Air and space transport accidents
0.691 0.309 0.000
V90-V94 Water transport accidents
0.691 0.309 0.000
V80-V89 Other land transport accidents
0.691 0.309 0.000
V70-V79 Bus occupant injured in transport accident
0.691 0.309 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.691 0.309 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.691 0.309 0.000
V40-V49 Car occupant injured in transport accident
0.691 0.309 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.691 0.309 0.000
V01-V09 Pedestrian injured in transport accident
0.691 0.309 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.691 0.309 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.691 0.309 0.000
J00 Acute nasopharyngitis [common cold]
0.690 0.310 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.689 0.310 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.689 0.311 0.000
E11.5 With peripheral circulatory complications
0.689 0.311 0.000
E10.1 With ketoacidosis
0.688 0.312 0.000
M65 Synovitis and tenosynovitis
0.688 0.312 0.000
N70 Salpingitis and oophoritis
0.688 0.312 0.000
G82 Paraplegia and tetraplegia
0.687 0.313 0.000
R47-R49 Symptoms and signs involving speech and voice
0.686 0.314 0.000
R01 Cardiac murmurs and other cardiac sounds
0.686 0.314 0.000
I42.9 Cardiomyopathy, unspecified
0.686 0.314 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.685 0.315 0.000
G93 Other disorders of brain
0.685 0.315 0.000
I61 Intracerebral haemorrhage
0.684 0.316 0.000
Z51.9 Medical care, unspecified
0.683 0.317 0.000
Z51.6 Desensitisation to allergens
0.683 0.317 0.000
Z35 Supervision of high-risk pregnancy
0.683 0.317 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.682 0.318 0.000
M51 Other intervertebral disk disorders
0.682 0.318 0.000
G70-G73 Diseases of myoneural junction and muscle
0.681 0.319 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.681 0.319 0.000
L03 Cellulitis
0.680 0.320 0.000
Z53.8 Procedure not carried out for other reasons
0.680 0.320 0.000
E83.4 Disorders of magnesium metabolism
0.679 0.320 0.000
I49.3 Ventricular premature depolarisation
0.679 0.321 0.000
G30-G32 Other degenerative diseases of the nervous system
0.678 0.321 0.000
L40 Psoriasis
0.676 0.324 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.676 0.324 0.000
M91-M94 Chondropathies
0.676 0.324 0.000
M60-M63 Disorders of muscles
0.676 0.324 0.000
M00-M03 Infectious arthropathies
0.676 0.324 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.676 0.324 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.674 0.326 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.673 0.327 0.000
C56 Malignant neoplasm of ovary
0.672 0.328 0.000
S89 Other and unspecified injuries of lower leg
0.672 0.328 0.000
N18.8 Other chronic renal failure
0.672 0.328 0.000
N18.2 Chronic kidney disease, stage 2
0.672 0.328 0.000
N18.1 Chronic kidney disease, stage 1
0.672 0.328 0.000
H71 Cholesteatoma of middle ear
0.672 0.328 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.671 0.328 0.000
M86-M90 Other osteopathies
0.671 0.328 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.671 0.329 0.000
R19.4 Change in bowel habit
0.671 0.329 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.671 0.329 0.000
R94 Abnormal results of function studies
0.671 0.329 0.000
N64 Other disorders of breast
0.671 0.329 0.000
I74 Arterial embolism and thrombosis
0.670 0.329 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.670 0.330 0.000
N13.3 Other and unspecified hydronephrosis
0.670 0.330 0.000
W19.9 Unspecified place
0.669 0.331 0.000
D10-D36 Benign neoplasms
0.669 0.331 0.000
J09-J18 Influenza and pneumonia
0.667 0.333 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.667 0.333 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.666 0.334 0.000
J95-J99 Other diseases of the respiratory system
0.666 0.334 0.000
R25 Abnormal involuntary movements
0.666 0.334 0.000
G83 Other paralytic syndromes
0.665 0.334 0.000
M47 Spondylosis
0.665 0.335 0.000
E87.2 Acidosis
0.665 0.335 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.664 0.336 0.000
Z30.2 Sterilisation
0.664 0.336 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.664 0.336 0.000
E83.8 Other disorders of mineral metabolism
0.664 0.336 0.000
E83.3 Disorders of phosphorus metabolism
0.664 0.336 0.000
E83.2 Disorders of zinc metabolism
0.664 0.336 0.000
E83.0 Disorders of copper metabolism
0.664 0.336 0.000
I24 Other acute ischaemic heart diseases
0.663 0.337 0.000
V10-V19 Pedal cyclist injured in transport accident
0.662 0.337 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.661 0.339 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.661 0.339 0.000
Z41 Procedures for purposes other than remedying health state
0.660 0.339 0.000
D69.6 Thrombocytopenia, unspecified
0.661 0.339 0.000
R15 Faecal incontinence
0.659 0.341 0.000
J02.9 Acute pharyngitis, unspecified
0.659 0.341 0.000
E20-E35 Disorders of other endocrine glands
0.658 0.342 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.658 0.342 0.000
N13.4 Hydroureter
0.658 0.342 0.000
G20-G26 Extrapyramidal and movement disorders
0.657 0.343 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.657 0.343 0.000
Z75 Problems related to medical facilities and other health care
0.656 0.344 0.000
N04 Nephrotic syndrome
0.656 0.344 0.000
S59 Other and unspecified injuries of forearm
0.655 0.344 0.000
S58 Traumatic amputation of forearm
0.655 0.344 0.000
S57 Crushing injury of forearm
0.655 0.344 0.000
S56 Injury of muscle and tendon at forearm level
0.655 0.344 0.000
S55 Injury of blood vessels at forearm level
0.655 0.344 0.000
S54 Injury of nerves at forearm level
0.655 0.344 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.655 0.344 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.655 0.345 0.000
H66 Suppurative and unspecified otitis media
0.655 0.345 0.000
N25-N29 Other disorders of kidney and ureter
0.655 0.345 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.655 0.345 0.000
R26 Abnormalities of gait and mobility
0.655 0.345 0.000
I42.0 Dilated cardiomyopathy
0.654 0.346 0.000
M15-M19 Arthrosis
0.654 0.346 0.000
Y59 Other and unspecified vaccines and biological substances
0.654 0.346 0.000
Y58 Bacterial vaccines
0.654 0.346 0.000
Y57 Other and unspecified drugs and medicaments
0.654 0.346 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.654 0.346 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.654 0.346 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.654 0.346 0.000
Y52 Agents primarily affecting the cardiovascular system
0.654 0.346 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.654 0.346 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.654 0.346 0.000
Y48 Anaesthetics and therapeutic gases
0.654 0.346 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.654 0.346 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.654 0.346 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.654 0.346 0.000
I71 Aortic aneurysm and dissection
0.653 0.347 0.000
C50-C50 Malignant neoplasm of breast
0.653 0.347 0.000
T51 Toxic effect of alcohol
0.653 0.347 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.653 0.347 0.000
E87.4 Mixed disorder of acid-base balance
0.653 0.347 0.000
E87.3 Alkalosis
0.653 0.347 0.000
E87.0 Hyperosmolality and hypernatraemia
0.653 0.347 0.000
W13 Fall from, out of or through building or structure
0.651 0.348 0.000
T92 Sequelae of injuries of upper limb
0.651 0.349 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.651 0.349 0.000
Y40 Systemic antibiotics
0.650 0.349 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.650 0.350 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.650 0.350 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.650 0.350 0.000
L50-L54 Urticaria and erythema
0.649 0.350 0.000
I69.3 Sequelae of cerebral infarction
0.649 0.351 0.000
C54 Malignant neoplasm of corpus uteri
0.648 0.352 0.000
N21.0 Calculus in bladder
0.647 0.353 0.000
M80-M85 Disorders of bone density and structure
0.646 0.354 0.000
J60-J70 Lung diseases due to external agents
0.646 0.354 0.000
G62 Other polyneuropathies
0.645 0.355 0.000
H43-H45 Disorders of vitreous body and globe
0.645 0.355 0.000
S52.60 Fracture of lower end of both ulna and radius (closed)
0.645 0.355 0.000
N75 Diseases of Bartholin's gland
0.645 0.355 0.000
I44.7 Left bundle-branch block, unspecified
0.644 0.355 0.000
R14 Flatulence and related conditions
0.643 0.357 0.000
S09 Other and unspecified injuries of head
0.642 0.358 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.642 0.358 0.000
S32.5 Fracture of pubis
0.641 0.359 0.000
L10-L14 Bullous disorders
0.641 0.359 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.640 0.360 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.640 0.360 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.640 0.360 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.640 0.360 0.000
I77 Other disorders of arteries and arterioles
0.640 0.360 0.000
S01.0 Open wound of scalp
0.639 0.361 0.000
A46 Erysipelas
0.639 0.361 0.000
H02 Other disorders of eyelid
0.639 0.361 0.000
C53 Malignant neoplasm of cervix uteri
0.638 0.362 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.637 0.363 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.637 0.363 0.000
S52.8 Fracture of other parts of forearm
0.637 0.363 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.637 0.363 0.000
S64 Injury of nerves at wrist and hand level
0.636 0.364 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.636 0.364 0.000
M40-M43 Deforming dorsopathies
0.636 0.364 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.636 0.364 0.000
N18.4 Chronic kidney disease, stage 4
0.636 0.364 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.636 0.364 0.000
N15 Other renal tubulo-interstitial diseases
0.636 0.364 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.636 0.364 0.000
N11 Chronic tubulo-interstitial nephritis
0.636 0.364 0.000
N10 Acute tubulo-interstitial nephritis
0.636 0.364 0.000
Z29 Need for other prophylactic measures
0.635 0.365 0.000
Z28 Immunisation not carried out
0.635 0.365 0.000
Z27 Need for immunisation against combinations of infectious diseases
0.635 0.365 0.000
Z26 Need for immunisation against other single infectious diseases
0.635 0.365 0.000
Z25 Need for immunisation against other single viral diseases
0.635 0.365 0.000
Z24 Need for immunisation against certain single viral diseases
0.635 0.365 0.000
Z23 Need for immunisation against single bacterial diseases
0.635 0.365 0.000
Z20 Contact with and exposure to communicable diseases
0.635 0.365 0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status
0.635 0.365 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.635 0.365 0.000
D55-D59 Haemolytic anaemias
0.635 0.365 0.000
N03.9 Unspecified
0.634 0.365 0.000
I72 Other aneurysm
0.633 0.367 0.000
U80 Agent resistant to penicillin and related antibiotics
0.633 0.367 0.000
I35 Nonrheumatic aortic valve disorders
0.632 0.368 0.000
S80 Superficial injury of lower leg
0.632 0.368 0.000
S81 Open wound of lower leg
0.632 0.368 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.632 0.368 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.631 0.369 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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