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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74840965
log Bayes Factor = 28.8326
Chromosome 7   position 39,677,916  (GRCh37) Explore rs74840965 on Ensembl!
Variant rs74840965 is part of Cluster X0139

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
N30-N39 Other diseases of urinary system
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
0.999 0.001 0.000
Chapter I Certain infectious and parasitic diseases
0.997 0.003 0.000
I60-I69 Cerebrovascular diseases
0.997 0.003 0.000
Chapter VII Diseases of the eye and adnexa
0.996 0.004 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.996 0.004 0.000
N39 Other disorders of urinary system
0.995 0.005 0.000
I25 Chronic ischaemic heart disease
0.994 0.006 0.000
R50-R69 General symptoms and signs
0.994 0.006 0.000
Chapter VI Diseases of the nervous system
0.990 0.010 0.000
C15-C26 Malignant neoplasms of digestive organs
0.990 0.010 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.987 0.013 0.000
N32 Other disorders of bladder
0.986 0.014 0.000
A30-A49 Other bacterial diseases
0.985 0.015 0.000
Z86 Personal history of certain other diseases
0.983 0.017 0.000
Z50 Care involving use of rehabilitation procedures
0.983 0.017 0.000
Z95.1 Presence of aortocoronary bypass graft
0.983 0.017 0.000
N10-N16 Renal tubulo-interstitial diseases
0.981 0.019 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.976 0.024 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.973 0.027 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.972 0.028 0.000
I67 Other cerebrovascular diseases
0.971 0.029 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.971 0.029 0.000
N39.4 Other specified urinary incontinence
0.969 0.031 0.000
C64-C68 Malignant neoplasms of urinary tract
0.969 0.031 0.000
Z85 Personal history of malignant neoplasm
0.967 0.033 0.000
N20-N23 Urolithiasis
0.967 0.033 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.966 0.034 0.000
G40-G47 Episodic and paroxysmal disorders
0.965 0.035 0.000
R51 Headache
0.964 0.036 0.000
N32.8 Other specified disorders of bladder
0.959 0.041 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.959 0.041 0.000
Z86.7 Personal history of diseases of the circulatory system
0.958 0.042 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.957 0.043 0.000
R56 Convulsions, not elsewhere classified
0.955 0.045 0.000
A41 Other septicaemia
0.954 0.046 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.954 0.046 0.000
Z86.0 Personal history of other neoplasms
0.953 0.047 0.000
C18 Malignant neoplasm of colon
0.952 0.048 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.950 0.050 0.000
I67.9 Cerebrovascular disease, unspecified
0.950 0.050 0.000
N20 Calculus of kidney and ureter
0.950 0.050 0.000
B95-B98 Bacterial, viral and other infectious agents
0.945 0.055 0.000
H30-H36 Disorders of choroid and retina
0.945 0.055 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.943 0.057 0.000
M05-M14 Inflammatory polyarthropathies
0.941 0.059 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.940 0.060 0.000
I21 Acute myocardial infarction
0.939 0.061 0.000
N13 Obstructive and reflux uropathy
0.939 0.061 0.000
N39.0 Urinary tract infection, site not specified
0.939 0.061 0.000
R30-R39 Symptoms and signs involving the urinary system
0.939 0.061 0.000
G40 Epilepsy
0.937 0.063 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.936 0.064 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.934 0.066 0.000
A41.9 Septicaemia, unspecified
0.933 0.067 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.932 0.068 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.929 0.071 0.000
R56.8 Other and unspecified convulsions
0.927 0.073 0.000
C67 Malignant neoplasm of bladder
0.925 0.075 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.924 0.076 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.924 0.076 0.000
I21.9 Acute myocardial infarction, unspecified
0.918 0.082 0.000
N30 Cystitis
0.918 0.082 0.000
H35 Other retinal disorders
0.917 0.083 0.000
R63 Symptoms and signs concerning food and fluid intake
0.917 0.083 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.913 0.087 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.912 0.088 0.000
A49 Bacterial infection of unspecified site
0.909 0.091 0.000
N20.1 Calculus of ureter
0.909 0.091 0.000
M13 Other arthritis
0.907 0.093 0.000
N60-N64 Disorders of breast
0.905 0.095 0.000
R35 Polyuria
0.905 0.095 0.000
C78.0 Secondary malignant neoplasm of lung
0.904 0.096 0.000
R47-R49 Symptoms and signs involving speech and voice
0.899 0.101 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.898 0.102 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.898 0.102 0.000
E10-E14 Diabetes mellitus
0.895 0.105 0.000
S60-S69 Injuries to the wrist and hand
0.893 0.107 0.000
C50-C50 Malignant neoplasm of breast
0.892 0.108 0.000
M50-M54 Other dorsopathies
0.891 0.109 0.000
O60-O75 Complications of labour and delivery
0.888 0.112 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.886 0.114 0.000
M70-M79 Other soft tissue disorders
0.886 0.114 0.000
R42 Dizziness and giddiness
0.885 0.115 0.000
M13.9 Arthritis, unspecified
0.883 0.117 0.000
Z51 Other medical care
0.883 0.117 0.000
N32.3 Diverticulum of bladder
0.882 0.118 0.000
Z93 Artificial opening status
0.878 0.122 0.000
R63.4 Abnormal weight loss
0.877 0.123 0.000
N39.3 Stress incontinence
0.876 0.124 0.000
Z51.2 Other chemotherapy
0.875 0.125 0.000
R60 Oedema, not elsewhere classified
0.875 0.125 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.874 0.126 0.000
H53-H54 Visual disturbances and blindness
0.873 0.127 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.872 0.128 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.872 0.128 0.000
G43 Migraine
0.867 0.133 0.000
I69 Sequelae of cerebrovascular disease
0.867 0.133 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.861 0.139 0.000
H40-H42 Glaucoma
0.855 0.145 0.000
C67.9 Bladder, unspecified
0.853 0.147 0.000
I61 Intracerebral haemorrhage
0.852 0.148 0.000
I25.1 Atherosclerotic heart disease
0.851 0.149 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.849 0.151 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.849 0.151 0.000
Chapter VIII Diseases of the ear and mastoid process
0.849 0.151 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.848 0.152 0.000
H35.3 Degeneration of macula and posterior pole
0.847 0.153 0.000
I63 Cerebral infarction
0.847 0.153 0.000
N20.2 Calculus of kidney with calculus of ureter
0.846 0.154 0.000
H55-H59 Other disorders of eye and adnexa
0.846 0.154 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.845 0.155 0.000
Z42 Follow-up care involving plastic surgery
0.845 0.155 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.844 0.156 0.000
Z47 Other orthopaedic follow-up care
0.843 0.157 0.000
I25.2 Old myocardial infarction
0.842 0.158 0.000
C18.9 Colon, unspecified
0.840 0.160 0.000
R47 Speech disturbances, not elsewhere classified
0.840 0.160 0.000
C18.2 Ascending colon
0.839 0.161 0.000
R32 Unspecified urinary incontinence
0.838 0.162 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.838 0.162 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.837 0.163 0.000
N99-N99 Other disorders of the genitourinary system
0.836 0.164 0.000
G40.9 Epilepsy, unspecified
0.836 0.164 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.835 0.165 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.832 0.168 0.000
N30.9 Cystitis, unspecified
0.830 0.170 0.000
A49.0 Staphylococcal infection, unspecified
0.826 0.174 0.000
H25-H28 Disorders of lens
0.824 0.176 0.000
Z50.8 Care involving use of rehabilitation procedures
0.823 0.177 0.000
E70-E90 Metabolic disorders
0.822 0.178 0.000
I60 Subarachnoid haemorrhage
0.822 0.178 0.000
E11 Non-insulin-dependent diabetes mellitus
0.822 0.178 0.000
Z48 Other surgical follow-up care
0.819 0.181 0.000
R27 Other lack of coordination
0.817 0.183 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.817 0.183 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.816 0.184 0.000
D60-D64 Aplastic and other anaemias
0.815 0.185 0.000
Z81 Family history of mental and behavioural disorders
0.815 0.185 0.000
C50 Malignant neoplasm of breast
0.815 0.185 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.813 0.187 0.000
R55 Syncope and collapse
0.813 0.187 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.812 0.188 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.811 0.189 0.000
N32.9 Bladder disorder, unspecified
0.810 0.190 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.810 0.190 0.000
Z93.2 Ileostomy status
0.809 0.191 0.000
C67.2 Lateral wall of bladder
0.809 0.191 0.000
Chapter XXII Codes for special purposes
0.808 0.192 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.808 0.192 0.000
M45-M49 Spondylopathies
0.806 0.194 0.000
G20-G26 Extrapyramidal and movement disorders
0.805 0.195 0.000
R26 Abnormalities of gait and mobility
0.805 0.195 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.804 0.196 0.000
G90-G99 Other disorders of the nervous system
0.804 0.196 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.804 0.196 0.000
Z97 Presence of other devices
0.802 0.198 0.000
I10-I15 Hypertensive diseases
0.802 0.198 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.800 0.200 0.000
Chapter XX External causes of morbidity and mortality
0.800 0.200 0.000
N11 Chronic tubulo-interstitial nephritis
0.799 0.201 0.000
Z96 Presence of other functional implants
0.797 0.203 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.796 0.204 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.795 0.205 0.000
Z50.0 Cardiac rehabilitation
0.795 0.205 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.795 0.205 0.000
N64 Other disorders of breast
0.795 0.205 0.000
D00-D09 In situ neoplasms
0.795 0.205 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.795 0.205 0.000
I05-I09 Chronic rheumatic heart diseases
0.795 0.205 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.791 0.209 0.000
N25-N29 Other disorders of kidney and ureter
0.789 0.211 0.000
I30-I52 Other forms of heart disease
0.789 0.211 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.788 0.212 0.000
S40-S49 Injuries to the shoulder and upper arm
0.786 0.214 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.785 0.215 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.784 0.216 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.784 0.216 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.783 0.216 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.783 0.217 0.000
N13.3 Other and unspecified hydronephrosis
0.783 0.217 0.000
B15-B19 Viral hepatitis
0.781 0.219 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.781 0.219 0.000
Z29 Need for other prophylactic measures
0.780 0.220 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.780 0.220 0.000
H52 Disorders of refraction and accommodation
0.780 0.220 0.000
M79.6 Pain in limb
0.779 0.221 0.000
I24 Other acute ischaemic heart diseases
0.775 0.225 0.000
Z46 Fitting and adjustment of other devices
0.774 0.226 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.774 0.226 0.000
S62 Fracture at wrist and hand level
0.773 0.227 0.000
H35.8 Other specified retinal disorders
0.772 0.228 0.000
M54 Dorsalgia
0.771 0.229 0.000
Z41 Procedures for purposes other than remedying health state
0.771 0.229 0.000
A80-A89 Viral infections of the central nervous system
0.771 0.229 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.770 0.230 0.000
R68 Other general symptoms and signs
0.770 0.230 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.770 0.230 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.770 0.230 0.000
O70 Perineal laceration during delivery
0.769 0.231 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.769 0.231 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.769 0.231 0.000
T66-T78 Other and unspecified effects of external causes
0.768 0.232 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.766 0.234 0.000
R39 Other symptoms and signs involving the urinary system
0.766 0.234 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.765 0.235 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.765 0.235 0.000
Z94 Transplanted organ and tissue status
0.764 0.236 0.000
C15 Malignant neoplasm of oesophagus
0.763 0.237 0.000
N10 Acute tubulo-interstitial nephritis
0.763 0.237 0.000
N00-N08 Glomerular diseases
0.762 0.238 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.762 0.238 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.762 0.238 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.761 0.239 0.000
E20-E35 Disorders of other endocrine glands
0.761 0.239 0.000
H25 Senile cataract
0.761 0.239 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.761 0.239 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.761 0.239 0.000
R60.0 Localised oedema
0.760 0.240 0.000
M51 Other intervertebral disk disorders
0.760 0.240 0.000
H54 Blindness and low vision
0.760 0.240 0.000
G70-G73 Diseases of myoneural junction and muscle
0.759 0.241 0.000
R47.8 Other and unspecified speech disturbances
0.759 0.241 0.000
C18.5 Splenic flexure
0.758 0.242 0.000
D50-D53 Nutritional anaemias
0.758 0.242 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.756 0.244 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.755 0.245 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.755 0.245 0.000
H40 Glaucoma
0.754 0.246 0.000
B25-B34 Other viral diseases
0.753 0.247 0.000
N20.0 Calculus of kidney
0.752 0.248 0.000
R25 Abnormal involuntary movements
0.751 0.249 0.000
H50 Other strabismus
0.748 0.252 0.000
H57 Other disorders of eye and adnexa
0.745 0.255 0.000
G43.9 Migraine, unspecified
0.744 0.256 0.000
N30.3 Trigonitis
0.744 0.256 0.000
S70-S79 Injuries to the hip and thigh
0.744 0.256 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.743 0.257 0.000
Z82.3 Family history of stroke
0.742 0.258 0.000
R34 Anuria and oliguria
0.741 0.259 0.000
Z22 Carrier of infectious disease
0.740 0.260 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.740 0.260 0.000
Z96.1 Presence of intraocular lens
0.739 0.261 0.000
H43-H45 Disorders of vitreous body and globe
0.738 0.262 0.000
M86-M90 Other osteopathies
0.738 0.262 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.736 0.264 0.000
H25.8 Other senile cataract
0.736 0.264 0.000
G44 Other headache syndromes
0.735 0.265 0.000
C50.4 Upper-outer quadrant of breast
0.735 0.265 0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.734 0.266 0.000
C25 Malignant neoplasm of pancreas
0.733 0.267 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.732 0.267 0.000
E86 Volume depletion
0.732 0.268 0.000
T79-T79 Certain early complications of trauma
0.732 0.268 0.000
E10 Insulin-dependent diabetes mellitus
0.732 0.268 0.000
N60 Benign mammary dysplasia
0.732 0.268 0.000
C80 Malignant neoplasm without specification of site
0.731 0.269 0.000
I67.1 Cerebral aneurysm, nonruptured
0.731 0.269 0.000
R29.6 Tendency to fall, not elsewhere classified
0.731 0.269 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.729 0.271 0.000
I80 Phlebitis and thrombophlebitis
0.729 0.271 0.000
G43.1 Migraine with aura [classical migraine]
0.729 0.271 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.728 0.272 0.000
H10-H13 Disorders of conjunctiva
0.728 0.272 0.000
E40-E46 Malnutrition
0.728 0.272 0.000
M10 Gout
0.727 0.273 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.727 0.273 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.727 0.273 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.726 0.274 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.725 0.275 0.000
I85 Oesophageal varices
0.725 0.275 0.000
M54.9 Dorsalgia, unspecified
0.725 0.275 0.000
I67.2 Cerebral atherosclerosis
0.724 0.275 0.000
S10-S19 Injuries to the neck
0.724 0.276 0.000
C18.4 Transverse colon
0.723 0.276 0.000
I22 Subsequent myocardial infarction
0.723 0.277 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.723 0.277 0.000
H35.0 Background retinopathy and retinal vascular changes
0.723 0.277 0.000
R50 Fever of unknown origin
0.722 0.278 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.722 0.278 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.721 0.278 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.718 0.282 0.000
A49.9 Bacterial infection, unspecified
0.718 0.282 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.718 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.717 0.283 0.000
N37 Urethral disorders in diseases classified elsewhere
0.717 0.283 0.000
N34 Urethritis and urethral syndrome
0.717 0.283 0.000
N33 Bladder disorders in diseases classified elsewhere
0.717 0.283 0.000
Z49 Care involving dialysis
0.717 0.283 0.000
Z89 Acquired absence of limb
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
C90.0 Multiple myeloma
0.717 0.283 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.716 0.284 0.000
I23 Certain current complications following acute myocardial infarction
0.716 0.284 0.000
N17-N19 Renal failure
0.716 0.284 0.000
O63 Long labour
0.715 0.285 0.000
N39.9 Disorder of urinary system, unspecified
0.715 0.285 0.000
B99-B99 Other infectious diseases
0.715 0.285 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.715 0.285 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.715 0.285 0.000
B65-B83 Helminthiases
0.715 0.285 0.000
B50-B64 Protozoal diseases
0.715 0.285 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.715 0.285 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.715 0.285 0.000
A75-A79 Rickettsioses
0.715 0.285 0.000
A70-A74 Other diseases caused by chlamydiae
0.715 0.285 0.000
A65-A69 Other spirochaetal diseases
0.715 0.285 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.715 0.285 0.000
A20-A28 Certain zoonotic bacterial diseases
0.715 0.285 0.000
A15-A19 Tuberculosis
0.715 0.285 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.715 0.285 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.715 0.285 0.000
H35.9 Retinal disorder, unspecified
0.715 0.285 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.714 0.286 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.714 0.286 0.000
D64 Other anaemias
0.714 0.286 0.000
C77.3 Axillary and upper limb lymph nodes
0.714 0.286 0.000
Z54 Convalescence
0.714 0.286 0.000
Z52 Donors of organs and tissues
0.714 0.286 0.000
Z44 Fitting and adjustment of external prosthetic device
0.714 0.286 0.000
N39.2 Orthostatic proteinuria, unspecified
0.713 0.287 0.000
N39.1 Persistent proteinuria, unspecified
0.713 0.287 0.000
I25.6 Silent myocardial ischaemia
0.713 0.287 0.000
I25.5 Ischaemic cardiomyopathy
0.713 0.287 0.000
I25.4 Coronary artery aneurysm
0.713 0.287 0.000
I25.3 Aneurysm of heart
0.713 0.287 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.713 0.287 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.713 0.287 0.000
R62 Lack of expected normal physiological development
0.713 0.287 0.000
R57 Shock, not elsewhere classified
0.713 0.287 0.000
R64 Cachexia
0.713 0.287 0.000
R58 Haemorrhage, not elsewhere classified
0.713 0.287 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.711 0.289 0.000
M07 Psoriatic and enteropathic arthropathies
0.711 0.289 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.711 0.289 0.000
G30-G32 Other degenerative diseases of the nervous system
0.710 0.290 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.710 0.290 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.710 0.290 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.710 0.290 0.000
C21 Malignant neoplasm of anus and anal canal
0.710 0.290 0.000
C17 Malignant neoplasm of small intestine
0.710 0.290 0.000
C23 Malignant neoplasm of gallbladder
0.710 0.290 0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm
0.709 0.291 0.000
I35 Nonrheumatic aortic valve disorders
0.709 0.291 0.000
H36 Retinal disorders in diseases classified elsewhere
0.708 0.292 0.000
C18.7 Sigmoid colon
0.708 0.292 0.000
Z04 Examination and observation for other reasons
0.708 0.292 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.708 0.292 0.000
Z95.3 Presence of xenogenic heart valve
0.708 0.292 0.000
N32.4 Rupture of bladder, nontraumatic
0.707 0.293 0.000
N32.2 Vesical fistula, not elsewhere classified
0.707 0.293 0.000
N32.1 Vesicointestinal fistula
0.707 0.293 0.000
A48 Other bacterial diseases, not elsewhere classified
0.706 0.293 0.000
A44 Bartonellosis
0.706 0.293 0.000
A43 Nocardiosis
0.706 0.293 0.000
A42 Actinomycosis
0.706 0.293 0.000
A40 Streptococcal septicaemia
0.706 0.293 0.000
A39 Meningococcal infection
0.706 0.293 0.000
A37 Whooping cough
0.706 0.293 0.000
A36 Diphtheria
0.706 0.293 0.000
A32 Listeriosis
0.706 0.293 0.000
A31 Infection due to other mycobacteria
0.706 0.293 0.000
A30 Leprosy [Hansen's disease]
0.706 0.293 0.000
A46 Erysipelas
0.706 0.293 0.000
A38 Scarlet fever
0.706 0.293 0.000
A35 Other tetanus
0.706 0.293 0.000
A34 Obstetrical tetanus
0.706 0.293 0.000
A33 Tetanus neonatorum
0.706 0.293 0.000
Z87 Personal history of other diseases and conditions
0.706 0.294 0.000
Z50.1 Other physical therapy
0.706 0.294 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.705 0.295 0.000
I63.9 Cerebral infarction, unspecified
0.705 0.295 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.705 0.295 0.000
O70.1 Second degree perineal laceration during delivery
0.705 0.295 0.000
Z50.6 Orthoptic training
0.704 0.295 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.704 0.295 0.000
Z50.3 Drug rehabilitation
0.704 0.295 0.000
Z50.2 Alcohol rehabilitation
0.704 0.295 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.704 0.296 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.703 0.297 0.000
N15 Other renal tubulo-interstitial diseases
0.703 0.297 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.703 0.297 0.000
Z48.0 Attention to surgical dressings and sutures
0.702 0.298 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.700 0.299 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.700 0.300 0.000
M91-M94 Chondropathies
0.700 0.300 0.000
M60-M63 Disorders of muscles
0.700 0.300 0.000
M00-M03 Infectious arthropathies
0.700 0.300 0.000
Z57 Occupational exposure to risk-factors
0.699 0.301 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.699 0.301 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.698 0.301 0.000
N21 Calculus of lower urinary tract
0.698 0.302 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.697 0.302 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.697 0.303 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.697 0.303 0.000
Z10 Routine general health check-up of defined subpopulation
0.697 0.303 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.696 0.303 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.696 0.303 0.000
I67.5 Moyamoya disease
0.696 0.303 0.000
I67.4 Hypertensive encephalopathy
0.696 0.303 0.000
I67.3 Progressive vascular leukoencephalopathy
0.696 0.303 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.696 0.303 0.000
T33-T35 Frostbite
0.696 0.304 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.696 0.304 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.696 0.304 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.696 0.304 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.696 0.304 0.000
T00-T07 Injuries involving multiple body regions
0.696 0.304 0.000
H35.4 Peripheral retinal degeneration
0.696 0.304 0.000
H34 Retinal vascular occlusions
0.696 0.304 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.695 0.305 0.000
C66 Malignant neoplasm of ureter
0.695 0.305 0.000
C65 Malignant neoplasm of renal pelvis
0.695 0.305 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.695 0.305 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.695 0.305 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.694 0.306 0.000
S62.6 Fracture of other finger
0.694 0.306 0.000
Z60 Problems related to social environment
0.694 0.306 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.693 0.306 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.693 0.306 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.693 0.307 0.000
H80-H83 Diseases of inner ear
0.692 0.308 0.000
I62 Other nontraumatic intracranial haemorrhage
0.692 0.308 0.000
Z50.5 Speech therapy
0.692 0.308 0.000
S20-S29 Injuries to the thorax
0.692 0.308 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.692 0.308 0.000
G41 Status epilepticus
0.692 0.308 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.692 0.308 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.692 0.308 0.000
Z13 Special screening examination for other diseases and disorders
0.691 0.309 0.000
R60.9 Oedema, unspecified
0.691 0.309 0.000
Z43 Attention to artificial openings
0.691 0.309 0.000
E11.3 With ophthalmic complications
0.691 0.309 0.000
S60 Superficial injury of wrist and hand
0.690 0.310 0.000
I86 Varicose veins of other sites
0.690 0.310 0.000
C16 Malignant neoplasm of stomach
0.690 0.310 0.000
N63 Unspecified lump in breast
0.690 0.310 0.000
E11.2 With renal complications
0.689 0.311 0.000
M47 Spondylosis
0.689 0.311 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.689 0.311 0.000
Z63 Other problems related to primary support group, including family circumstances
0.689 0.311 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.689 0.311 0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.689 0.311 0.000
I21.4 Acute subendocardial myocardial infarction
0.689 0.311 0.000
I87 Other disorders of veins
0.688 0.312 0.000
M05 Seropositive rheumatoid arthritis
0.688 0.312 0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm
0.687 0.313 0.000
C50.1 Central portion of breast
0.686 0.314 0.000
M79.0 Rheumatism, unspecified
0.685 0.314 0.000
H90-H95 Other disorders of ear
0.685 0.315 0.000
A49.8 Other bacterial infections of unspecified site
0.685 0.315 0.000
E14 Unspecified diabetes mellitus
0.685 0.315 0.000
R56.0 Febrile convulsions
0.684 0.315 0.000
Z83 Family history of other specific disorders
0.684 0.315 0.000
R39.1 Other difficulties with micturition
0.684 0.316 0.000
H52.1 Myopia
0.684 0.316 0.000
A41.8 Other specified septicaemia
0.684 0.316 0.000
A41.4 Septicaemia due to anaerobes
0.684 0.316 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.684 0.316 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.684 0.316 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.684 0.316 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.684 0.316 0.000
D10-D36 Benign neoplasms
0.683 0.317 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.683 0.317 0.000
Z81.8 Family history of other mental and behavioural disorders
0.683 0.317 0.000
C18.8 Overlapping lesion of colon
0.682 0.317 0.000
C18.6 Descending colon
0.682 0.317 0.000
C18.3 Hepatic flexure
0.682 0.317 0.000
C18.1 Appendix
0.682 0.317 0.000
M40-M43 Deforming dorsopathies
0.682 0.317 0.000
H40.0 Glaucoma suspect
0.682 0.318 0.000
D46 Myelodysplastic syndromes
0.682 0.318 0.000
I10 Essential (primary) hypertension
0.682 0.318 0.000
N20.9 Urinary calculus, unspecified
0.681 0.319 0.000
R27.8 Other and unspecified lack of coordination
0.681 0.319 0.000
H53 Visual disturbances
0.681 0.319 0.000
D61 Other aplastic anaemias
0.680 0.320 0.000
I46 Cardiac arrest
0.679 0.321 0.000
N36 Other disorders of urethra
0.679 0.321 0.000
S68 Traumatic amputation of wrist and hand
0.678 0.322 0.000
R47.0 Dysphasia and aphasia
0.678 0.322 0.000
M77 Other enthesopathies
0.678 0.322 0.000
Z95.2 Presence of prosthetic heart valve
0.678 0.322 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.678 0.322 0.000
H31 Other disorders of choroid
0.678 0.322 0.000
H30 Chorioretinal inflammation
0.678 0.322 0.000
O62 Abnormalities of forces of labour
0.676 0.324 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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