TreeWAS – Variant ID: rs74850413

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter IX Diseases of the circulatory system	0.999	0.001
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.999	0.001
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.999	0.001
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.999	0.001
Chapter IV Endocrine, nutritional and metabolic diseases	0.998	0.002
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.997	0.003
Chapter XIV Diseases of the genitourinary system	0.997	0.003
N17-N19 Renal failure	0.993	0.007
D60-D64 Aplastic and other anaemias	0.993	0.007
E70-E90 Metabolic disorders	0.992	0.008
I70-I79 Diseases of arteries, arterioles and capillaries	0.992	0.008
N17 Acute renal failure	0.991	0.009
N17.9 Acute renal failure, unspecified	0.988	0.012
N70-N77 Inflammatory diseases of female pelvic organs	0.986	0.014
D64 Other anaemias	0.985	0.015
I20-I25 Ischaemic heart diseases	0.982	0.018
D64.9 Anaemia, unspecified	0.979	0.021
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.973	0.027
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.971	0.029
M20-M25 Other joint disorders	0.966	0.034
E00-E07 Disorders of thyroid gland	0.965	0.035
E87 Other disorders of fluid, electrolyte and acid-base balance	0.965	0.035
M80-M85 Disorders of bone density and structure	0.957	0.043
I20 Angina pectoris	0.954	0.046
E03 Other hypothyroidism	0.954	0.046
I30-I52 Other forms of heart disease	0.951	0.049
E03.9 Hypothyroidism, unspecified	0.946	0.054
I77 Other disorders of arteries and arterioles	0.941	0.059
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.938	0.062
I51 Complications and ill-defined descriptions of heart disease	0.936	0.064
I20.0 Unstable angina	0.933	0.067
R42 Dizziness and giddiness	0.931	0.069
E86 Volume depletion	0.928	0.072
M70-M79 Other soft tissue disorders	0.926	0.074
R05 Cough	0.924	0.076
Chapter XX External causes of morbidity and mortality	0.923	0.077
R04 Haemorrhage from respiratory passages	0.921	0.079
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.920	0.080
N70 Salpingitis and oophoritis	0.911	0.089
M84 Disorders of continuity of bone	0.911	0.089
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.909	0.091
Chapter V Mental and behavioural disorders	0.906	0.094
Chapter XV Pregnancy, childbirth and the puerperium	0.905	0.095
N72 Inflammatory disease of cervix uteri	0.905	0.095
M25 Other joint disorders, not elsewhere classified	0.900	0.100
R02 Gangrene, not elsewhere classified	0.900	0.100
D50-D53 Nutritional anaemias	0.900	0.100
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.899	0.101
N25-N29 Other disorders of kidney and ureter	0.897	0.103
R04.2 Haemoptysis	0.896	0.104
S20-S29 Injuries to the thorax	0.896	0.104
E87.0 Hyperosmolality and hypernatraemia	0.892	0.108
I72 Other aneurysm	0.892	0.108
I35 Nonrheumatic aortic valve disorders	0.891	0.109
I51.8 Other ill-defined heart diseases	0.889	0.111
M24 Other specific joint derangements	0.889	0.111
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.886	0.114
I22 Subsequent myocardial infarction	0.883	0.117
S32 Fracture of lumbar spine and pelvis	0.880	0.120
M84.1 Nonunion of fracture [pseudarthrosis]	0.877	0.123
Chapter VI Diseases of the nervous system	0.870	0.130
I21 Acute myocardial infarction	0.868	0.132
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.866	0.134
N76 Other inflammation of vagina and vulva	0.865	0.135
E87.3 Alkalosis	0.864	0.136
M22 Disorders of patella	0.860	0.140
E78.5 Hyperlipidaemia, unspecified	0.859	0.141
N70.1 Chronic salpingitis and oophoritis	0.858	0.142
R03 Abnormal blood-pressure reading, without diagnosis	0.856	0.144
I71 Aortic aneurysm and dissection	0.853	0.147
I73 Other peripheral vascular diseases	0.849	0.151
R01 Cardiac murmurs and other cardiac sounds	0.846	0.154
S40-S49 Injuries to the shoulder and upper arm	0.844	0.156
O20-O29 Other maternal disorders predominantly related to pregnancy	0.844	0.156
I51.9 Heart disease, unspecified	0.841	0.159
R20 Disturbances of skin sensation	0.839	0.161
Chapter XXII Codes for special purposes	0.838	0.162
I95-I99 Other and unspecified disorders of the circulatory system	0.833	0.167
S90-S99 Injuries to the ankle and foot	0.832	0.168
E20-E35 Disorders of other endocrine glands	0.831	0.169
D80-D89 Certain disorders involving the immune mechanism	0.830	0.170
N20-N23 Urolithiasis	0.829	0.171
M72 Fibroblastic disorders	0.825	0.175
T66-T78 Other and unspecified effects of external causes	0.824	0.176
M45-M49 Spondylopathies	0.824	0.176
E87.5 Hyperkalaemia	0.822	0.178
D68 Other coagulation defects	0.821	0.179
T15-T19 Effects of foreign body entering through natural orifice	0.819	0.181
R50-R69 General symptoms and signs	0.818	0.182
N28 Other disorders of kidney and ureter, not elsewhere classified	0.817	0.183
M25.4 Effusion of joint	0.817	0.183
Q60-Q64 Congenital malformations of the urinary system	0.814	0.186
R07 Pain in throat and chest	0.813	0.187
W20-W49 Exposure to inanimate mechanical forces	0.811	0.189
N71 Inflammatory disease of uterus, except cervix	0.811	0.189
R00 Abnormalities of heart beat	0.811	0.189
G80-G83 Cerebral palsy and other paralytic syndromes	0.811	0.189
R03.1 Nonspecific low blood-pressure reading	0.807	0.193
I77.6 Arteritis, unspecified	0.805	0.195
R20.8 Other and unspecified disturbances of skin sensation	0.803	0.197
N17.0 Acute renal failure with tubular necrosis	0.800	0.199
D62 Acute posthaemorrhagic anaemia	0.798	0.202
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.796	0.204
R07.2 Precordial pain	0.795	0.205
I20.9 Angina pectoris, unspecified	0.789	0.211
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.789	0.211
Chapter XI Diseases of the digestive system	0.785	0.215
I77.8 Other specified disorders of arteries and arterioles	0.784	0.216
I21.1 Acute transmural myocardial infarction of inferior wall	0.783	0.217
S27 Injury of other and unspecified intrathoracic organs	0.783	0.217
R44 Other symptoms and signs involving general sensations and perceptions	0.782	0.218
R41 Other symptoms and signs involving cognitive functions and awareness	0.781	0.219
S22 Fracture of rib(s), sternum and thoracic spine	0.780	0.220
I77.1 Stricture of artery	0.779	0.221
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.779	0.221
M91-M94 Chondropathies	0.778	0.222
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.777	0.223
F30-F39 Mood [affective] disorders	0.775	0.225
S70-S79 Injuries to the hip and thigh	0.775	0.225
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.773	0.227
Q00-Q07 Congenital malformations of the nervous system	0.773	0.227
M71 Other bursopathies	0.771	0.229
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.770	0.230
M30 Polyarteritis nodosa and related conditions	0.768	0.232
N19 Unspecified renal failure	0.768	0.232
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.766	0.234
N23 Unspecified renal colic	0.764	0.236
M85 Other disorders of bone density and structure	0.762	0.238
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.762	0.238
N76.0 Acute vaginitis	0.761	0.239
I72.0 Aneurysm of carotid artery	0.761	0.239
F00-F09 Organic, including symptomatic, mental disorders	0.760	0.240
D50 Iron deficiency anaemia	0.760	0.240
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.759	0.241
N28.9 Disorder of kidney and ureter, unspecified	0.757	0.243
R09.1 Pleurisy	0.757	0.243
M76 Enthesopathies of lower limb, excluding foot	0.756	0.244
I51.7 Cardiomegaly	0.756	0.244
E50-E64 Other nutritional deficiencies	0.755	0.245
M05-M14 Inflammatory polyarthropathies	0.755	0.245
I35.1 Aortic (valve) insufficiency	0.755	0.245
I72.9 Aneurysm of unspecified site	0.754	0.246
N00-N08 Glomerular diseases	0.754	0.246
I22.1 Subsequent myocardial infarction of inferior wall	0.753	0.247
S32.4 Fracture of acetabulum	0.753	0.247
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.752	0.247
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.752	0.248
M24.0 Loose body in joint	0.752	0.248
G81 Hemiplegia	0.752	0.248
I30 Acute pericarditis	0.751	0.249
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.749	0.251
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.749	0.251
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.748	0.252
E87.7 Fluid overload	0.748	0.252
O85-O92 Complications predominantly related to the puerperium	0.747	0.253
R53 Malaise and fatigue	0.746	0.254
I35.2 Aortic (valve) stenosis with insufficiency	0.746	0.254
W22 Striking against or struck by other objects	0.746	0.254
Q50-Q56 Congenital malformations of genital organs	0.745	0.255
E87.1 Hypo-osmolality and hyponatraemia	0.745	0.255
Q80-Q89 Other congenital malformations	0.744	0.256
I21.4 Acute subendocardial myocardial infarction	0.744	0.256
D63 Anaemia in chronic diseases classified elsewhere	0.744	0.256
Chapter I Certain infectious and parasitic diseases	0.743	0.257
D61 Other aplastic anaemias	0.743	0.257
I77.9 Disorder of arteries and arterioles, unspecified	0.743	0.257
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.743	0.257
O26 Maternal care for other conditions predominantly related to pregnancy	0.741	0.259
F99-F99 Unspecified mental disorder	0.741	0.259
R57 Shock, not elsewhere classified	0.741	0.259
S32.5 Fracture of pubis	0.738	0.262
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.737	0.263
N28.0 Ischaemia and infarction of kidney	0.737	0.263
I35.8 Other aortic valve disorders	0.737	0.263
I70 Atherosclerosis	0.737	0.263
M70 Soft tissue disorders related to use, overuse and pressure	0.736	0.264
M24.2 Disorder of ligament	0.735	0.264
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.735	0.264
M22.8 Other disorders of patella	0.735	0.265
M22.2 Patellofemoral disorders	0.727	0.273
X60-X84 Intentional self-harm	0.726	0.274
M00-M03 Infectious arthropathies	0.726	0.274
K82 Other diseases of gallbladder	0.725	0.275
E23 Hypofunction and other disorders of pituitary gland	0.725	0.275
I73.9 Peripheral vascular disease, unspecified	0.725	0.275
N76.4 Abscess of vulva	0.723	0.277
S10-S19 Injuries to the neck	0.723	0.277
S32.0 Fracture of lumbar vertebra	0.723	0.277
V40-V49 Car occupant injured in transport accident	0.722	0.278
D68.8 Other specified coagulation defects	0.721	0.279
Y60-Y69 Misadventures to patients during surgical and medical care	0.721	0.279
T79-T79 Certain early complications of trauma	0.720	0.280
I05-I09 Chronic rheumatic heart diseases	0.719	0.281
G35-G37 Demyelinating diseases of the central nervous system	0.718	0.282
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.717	0.283
I00-I02 Acute rheumatic fever	0.716	0.283
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere	0.716	0.284
R95-R99 Ill-defined and unknown causes of mortality	0.716	0.284
R00.8 Other and unspecified abnormalities of heart beat	0.716	0.284
M25.7 Osteophyte	0.716	0.284
D55-D59 Haemolytic anaemias	0.716	0.284
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.716	0.284
T78 Adverse effects, not elsewhere classified	0.716	0.284
I47 Paroxysmal tachycardia	0.716	0.284
M60-M63 Disorders of muscles	0.715	0.285
I46 Cardiac arrest	0.715	0.285
S42 Fracture of shoulder and upper arm	0.713	0.287
E78.9 Disorder of lipoprotein metabolism, unspecified	0.713	0.287
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.712	0.288
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.712	0.288
W00-W19 Falls	0.712	0.288
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.712	0.288
M82 Osteoporosis in diseases classified elsewhere	0.712	0.288
O32 Maternal care for known or suspected malpresentation of foetus	0.711	0.289
E85 Amyloidosis	0.711	0.289
E84 Cystic fibrosis	0.711	0.289
E79 Disorders of purine and pyrimidine metabolism	0.711	0.289
E77 Disorders of glycoprotein metabolism	0.711	0.289
E76 Disorders of glycosaminoglycan metabolism	0.711	0.289
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.711	0.289
E74 Other disorders of carbohydrate metabolism	0.711	0.289
E73 Lactose intolerance	0.711	0.289
E72 Other disorders of amino-acid metabolism	0.711	0.289
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.711	0.289
E70 Disorders of aromatic amino-acid metabolism	0.711	0.289
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.711	0.289
M25.47 Effusion of joint (Ankle and foot)	0.711	0.289
N17.8 Other acute renal failure	0.710	0.290
N17.2 Acute renal failure with medullary necrosis	0.710	0.290
N17.1 Acute renal failure with acute cortical necrosis	0.710	0.290
G81.9 Hemiplegia, unspecified	0.709	0.291
D53 Other nutritional anaemias	0.708	0.292
R45 Symptoms and signs involving emotional state	0.707	0.293
X10-X19 Contact with heat and hot substances	0.707	0.293
E78.1 Pure hyperglyceridaemia	0.707	0.293
R01.1 Cardiac murmur, unspecified	0.707	0.293
N74 Female pelvic inflammatory disorders in diseases classified elsewhere	0.707	0.293
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.707	0.293
D64.8 Other specified anaemias	0.706	0.294
D64.4 Congenital dyserythropoietic anaemia	0.706	0.294
D64.3 Other sideroblastic anaemias	0.706	0.294
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.706	0.294
D64.1 Secondary sideroblastic anaemia due to disease	0.706	0.294
D64.0 Hereditary sideroblastic anaemia	0.706	0.294
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.706	0.294
M10 Gout	0.705	0.295
M46 Other inflammatory spondylopathies	0.704	0.296
I23 Certain current complications following acute myocardial infarction	0.704	0.296
F60-F69 Disorders of adult personality and behaviour	0.704	0.296
M25.9 Joint disorder, unspecified	0.704	0.296
I22.9 Subsequent myocardial infarction of unspecified site	0.703	0.297
M24.1 Other articular cartilage disorders	0.703	0.297
I33 Acute and subacute endocarditis	0.701	0.299
E78.8 Other disorders of lipoprotein metabolism	0.701	0.299
F40-F48 Neurotic, stress-related and somatoform disorders	0.701	0.299
K20-K31 Diseases of oesophagus, stomach and duodenum	0.700	0.300
O26.8 Other specified pregnancy-related conditions	0.700	0.300
G30-G32 Other degenerative diseases of the nervous system	0.699	0.301
W22.9 Unspecified place	0.699	0.301
M80 Osteoporosis with pathological fracture	0.698	0.302
E06 Thyroiditis	0.698	0.302
W50-W64 Exposure to animate mechanical forces	0.698	0.302
E88 Other metabolic disorders	0.697	0.302
T33-T35 Frostbite	0.697	0.303
T26-T28 Burns and corrosions confined to eye and internal organs	0.697	0.303
T20-T25 Burns and corrosions of external body surface, specified by site	0.697	0.303
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.697	0.303
T00-T07 Injuries involving multiple body regions	0.697	0.303
S27.0 Traumatic pneumothorax	0.697	0.303
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.697	0.303
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.696	0.304
R46 Symptoms and signs involving appearance and behaviour	0.696	0.304
R43 Disturbances of smell and taste	0.696	0.304
D52 Folate deficiency anaemia	0.696	0.304
X20-X29 Contact with venomous animals and plants	0.696	0.304
M81 Osteoporosis without pathological fracture	0.695	0.305
E40-E46 Malnutrition	0.694	0.306
K80 Cholelithiasis	0.694	0.306
R60 Oedema, not elsewhere classified	0.693	0.307
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.693	0.307
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.693	0.307
M34 Systemic sclerosis	0.693	0.307
M33 Dermatopolymyositis	0.693	0.307
M32 Systemic lupus erythematosus	0.693	0.307
X58-X59 Accidental exposure to other and unspecified factors	0.692	0.308
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.692	0.308
E00 Congenital iodine-deficiency syndrome	0.692	0.308
E02 Subclinical iodine-deficiency hypothyroidism	0.692	0.308
E87.4 Mixed disorder of acid-base balance	0.692	0.308
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.691	0.309
S22.4 Multiple fractures of ribs	0.691	0.309
I22.0 Subsequent myocardial infarction of anterior wall	0.691	0.309
R06 Abnormalities of breathing	0.690	0.310
I78 Diseases of capillaries	0.690	0.310
M86-M90 Other osteopathies	0.689	0.311
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.689	0.311
I24 Other acute ischaemic heart diseases	0.688	0.312
K31 Other diseases of stomach and duodenum	0.687	0.313
M83 Adult osteomalacia	0.686	0.313
M24.8 Other specific joint derangements, not elsewhere classified	0.686	0.314
R57.2 Septic shock	0.686	0.314
N71.1 Chronic inflammatory disease of uterus	0.685	0.315
M25.46 Effusion of joint (Lower leg)	0.685	0.315
D51 Vitamin B12 deficiency anaemia	0.684	0.316
E03.8 Other specified hypothyroidism	0.684	0.316
E03.5 Myxoedema coma	0.684	0.316
E03.4 Atrophy of thyroid (acquired)	0.684	0.316
E03.3 Postinfectious hypothyroidism	0.684	0.316
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.684	0.316
E03.1 Congenital hypothyroidism without goitre	0.684	0.316
E03.0 Congenital hypothyroidism with diffuse goitre	0.684	0.316
I52 Other heart disorders in diseases classified elsewhere	0.682	0.318
I48 Atrial fibrillation and flutter	0.682	0.318
I43 Cardiomyopathy in diseases classified elsewhere	0.682	0.318
I41 Myocarditis in diseases classified elsewhere	0.682	0.318
I40 Acute myocarditis	0.682	0.318
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.682	0.318
I37 Pulmonary valve disorders	0.682	0.318
I36 Nonrheumatic tricuspid valve disorders	0.682	0.318
I32 Pericarditis in diseases classified elsewhere	0.682	0.318
M25.6 Stiffness of joint, not elsewhere classified	0.682	0.318
T17 Foreign body in respiratory tract	0.682	0.318
K83 Other diseases of biliary tract	0.682	0.318
R44.3 Hallucinations, unspecified	0.681	0.319
A30-A49 Other bacterial diseases	0.680	0.320
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.680	0.320
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.679	0.321
O20 Haemorrhage in early pregnancy	0.679	0.321
D50.9 Iron deficiency anaemia, unspecified	0.678	0.322
I77.5 Necrosis of artery	0.675	0.325
I77.4 Coeliac artery compression syndrome	0.675	0.325
I77.3 Arterial fibromuscular dysplasia	0.675	0.325
I77.2 Rupture of artery	0.675	0.325
I77.0 Arteriovenous fistula, acquired	0.675	0.325
S90 Superficial injury of ankle and foot	0.674	0.326
R22.1 Localised swelling, mass and lump, neck	0.674	0.326
E80 Disorders of porphyrin and bilirubin metabolism	0.674	0.326
S32.1 Fracture of sacrum	0.674	0.326
K31.9 Disease of stomach and duodenum, unspecified	0.673	0.327
Q38-Q45 Other congenital malformations of the digestive system	0.673	0.327
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.672	0.328
Q35-Q37 Cleft lip and cleft palate	0.672	0.328
Q30-Q34 Congenital malformations of the respiratory system	0.672	0.328
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.672	0.328
R09.3 Abnormal sputum	0.671	0.329
I51.6 Cardiovascular disease, unspecified	0.671	0.329
I51.5 Myocardial degeneration	0.671	0.329
I51.4 Myocarditis, unspecified	0.671	0.329
I51.3 Intracardiac thrombosis, not elsewhere classified	0.671	0.329
I51.2 Rupture of papillary muscle, not elsewhere classified	0.671	0.329
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.671	0.329
I51.0 Cardiac septal defect, acquired	0.671	0.329
N26 Unspecified contracted kidney	0.670	0.330
O21 Excessive vomiting in pregnancy	0.670	0.330
R40 Somnolence, stupor and coma	0.669	0.331
M10.9 Gout, unspecified	0.669	0.331
T31 Burns classified according to extent of body surface involved	0.669	0.331
N75 Diseases of Bartholin's gland	0.667	0.332
Q61 Cystic kidney disease	0.667	0.333
O28 Abnormal findings on antenatal screening of mother	0.664	0.336
M73 Soft tissue disorders in diseases classified elsewhere	0.664	0.336
E20 Hypoparathyroidism	0.664	0.336
D68.9 Coagulation defect, unspecified	0.663	0.337
S72 Fracture of femur	0.662	0.337
F80-F89 Disorders of psychological development	0.662	0.338
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.662	0.338
S32.40 Fracture of acetabulum (closed)	0.662	0.338
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.661	0.338
Y35-Y36 Legal intervention and operations of war	0.661	0.338
Y10-Y34 Event of undetermined intent	0.661	0.338
Y00-Y09 Assault	0.661	0.338
X85-X99 Assault	0.661	0.338
X50-X57 Overexertion, travel and privation	0.661	0.338
X30-X39 Exposure to forces of nature	0.661	0.338
X00-X09 Exposure to smoke, fire and flames	0.661	0.338
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.661	0.338
W75-W84 Other accidental threats to breathing	0.661	0.338
W65-W74 Accidental drowning and submersion	0.661	0.338
V98-V99 Other and unspecified transport accidents	0.661	0.338
V95-V97 Air and space transport accidents	0.661	0.338
V90-V94 Water transport accidents	0.661	0.338
V80-V89 Other land transport accidents	0.661	0.338
V70-V79 Bus occupant injured in transport accident	0.661	0.338
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.661	0.338
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.661	0.338
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.661	0.338
V01-V09 Pedestrian injured in transport accident	0.661	0.338
I34 Nonrheumatic mitral valve disorders	0.661	0.339
M21 Other acquired deformities of limbs	0.661	0.339
R04.9 Haemorrhage from respiratory passages, unspecified	0.660	0.340
R04.8 Haemorrhage from other sites in respiratory passages	0.660	0.340
R04.1 Haemorrhage from throat	0.660	0.340
N18 Chronic renal failure	0.660	0.340
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.660	0.340
S37 Injury of urinary and pelvic organs	0.660	0.340
S36 Injury of intra-abdominal organs	0.660	0.340
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.660	0.340
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.660	0.340
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.660	0.340
S31 Open wound of abdomen, lower back and pelvis	0.660	0.340
K82.8 Other specified diseases of gallbladder	0.659	0.341
U80 Agent resistant to penicillin and related antibiotics	0.659	0.341
R01.0 Benign and innocent cardiac murmurs	0.659	0.341
E05 Thyrotoxicosis [hyperthyroidism]	0.658	0.342
R94 Abnormal results of function studies	0.658	0.342
G00-G09 Inflammatory diseases of the central nervous system	0.657	0.343
I35.0 Aortic (valve) stenosis	0.656	0.344
R23 Other skin changes	0.655	0.345
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.655	0.345
Q63 Other congenital malformations of kidney	0.655	0.345
Q05 Spina bifida	0.654	0.346
N70.9 Salpingitis and oophoritis, unspecified	0.653	0.346
N70.0 Acute salpingitis and oophoritis	0.653	0.346
M24.02 Loose body in joint (Upper arm)	0.653	0.347
O41 Other disorders of amniotic fluid and membranes	0.653	0.347
M84.9 Disorder of continuity of bone, unspecified	0.653	0.347
M84.8 Other disorders of continuity of bone	0.653	0.347
M84.4 Pathological fracture, not elsewhere classified	0.653	0.347
M84.3 Stress fracture, not elsewhere classified	0.653	0.347
M84.2 Delayed union of fracture	0.653	0.347
M84.0 Malunion of fracture	0.653	0.347
M25.3 Other instability of joint	0.652	0.348
S46 Injury of muscle and tendon at shoulder and upper arm level	0.652	0.348
R41.3 Other amnesia	0.651	0.348
F33 Recurrent depressive disorder	0.651	0.349
I73.0 Raynaud's syndrome	0.650	0.350
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.649	0.350
F70-F79 Mental retardation	0.649	0.350
N73 Other female pelvic inflammatory diseases	0.649	0.351
I35.9 Aortic valve disorder, unspecified	0.649	0.351
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.648	0.352
G83 Other paralytic syndromes	0.647	0.352
I95 Hypotension	0.647	0.353
Y95 Nosocomial condition	0.646	0.354
Y44 Agents primarily affecting blood constituents	0.646	0.354
M40-M43 Deforming dorsopathies	0.645	0.354
M25.2 Flail joint	0.645	0.354
M25.1 Fistula of joint	0.645	0.354
M25.0 Haemarthrosis	0.645	0.354
O94-O99 Other obstetric conditions, not elsewhere classified	0.645	0.355
R50 Fever of unknown origin	0.645	0.355
M35 Other systemic involvement of connective tissue	0.645	0.355
E78.6 Lipoprotein deficiency	0.645	0.355
E78.4 Other hyperlipidaemia	0.645	0.355
E78.3 Hyperchylomicronaemia	0.645	0.355
I99 Other and unspecified disorders of circulatory system	0.644	0.356
R00.1 Bradycardia, unspecified	0.644	0.356
E34 Other endocrine disorders	0.644	0.356
N29 Other disorders of kidney and ureter in diseases classified elsewhere	0.643	0.357
N27 Small kidney of unknown cause	0.643	0.357
N25 Disorders resulting from impaired renal tubular function	0.643	0.357
S99 Other and unspecified injuries of ankle and foot	0.643	0.357
N60-N64 Disorders of breast	0.643	0.357
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.643	0.357
S29 Other and unspecified injuries of thorax	0.642	0.358
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.642	0.358
S26 Injury of heart	0.642	0.358
S25 Injury of blood vessels of thorax	0.642	0.358
S24 Injury of nerves and spinal cord at thorax level	0.642	0.358
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.642	0.358
S21 Open wound of thorax	0.642	0.358
M79 Other soft tissue disorders, not elsewhere classified	0.642	0.358
D68.6 Other Thrombophilia	0.642	0.358
X40-X49 Accidental poisoning by and exposure to noxious substances	0.641	0.359
N99-N99 Other disorders of the genitourinary system	0.641	0.359
K29 Gastritis and duodenitis	0.640	0.360
I72.8 Aneurysm of other specified arteries	0.639	0.361
I72.6 Aneurysm and dissection of vertebral artery	0.639	0.361
I72.5 Aneurysm and dissection of other precerebral arteries	0.639	0.361
I72.4 Aneurysm of artery of lower extremity	0.639	0.361
I72.3 Aneurysm of iliac artery	0.639	0.361
I72.2 Aneurysm of renal artery	0.639	0.361
I72.1 Aneurysm of artery of upper extremity	0.639	0.361
I38 Endocarditis, valve unspecified	0.638	0.362
O40 Polyhydramnios	0.638	0.362
M25.5 Pain in joint	0.638	0.362
S30 Superficial injury of abdomen, lower back and pelvis	0.637	0.363
M24.9 Joint derangement, unspecified	0.637	0.363
M24.7 Protrusio acetabuli	0.637	0.363
M24.6 Ankylosis of joint	0.637	0.363
M24.5 Contracture of joint	0.637	0.363
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.637	0.363
S32.50 Fracture of pubis (closed)	0.637	0.363
D68.5 Primary Thrombophilia	0.636	0.364
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.636	0.364
D89.2 Hypergammaglobulinaemia, unspecified	0.636	0.364
I20.1 Angina pectoris with documented spasm	0.635	0.365
M47 Spondylosis	0.635	0.365
M76.6 Achilles tendinitis	0.635	0.365
D67 Hereditary factor IX deficiency	0.635	0.365
D66 Hereditary factor VIII deficiency	0.635	0.365
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.635	0.365
M71.2 Synovial cyst of popliteal space [Baker]	0.634	0.366
E23.2 Diabetes insipidus	0.633	0.367
I22.8 Subsequent myocardial infarction of other sites	0.633	0.367
T18 Foreign body in alimentary tract	0.632	0.367
M31 Other necrotising vasculopathies	0.631	0.369
S32.7 Multiple fractures of lumbar spine and pelvis	0.631	0.369

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations