TreeWAS – Variant ID: rs74958267

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
# Top node	1.000	0.000
M45-M49 Spondylopathies	1.000	0.000
M50-M54 Other dorsopathies	1.000	0.000
M47 Spondylosis	0.999	0.001
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.996	0.004
Chapter VI Diseases of the nervous system	0.994	0.006
M05-M14 Inflammatory polyarthropathies	0.993	0.007
M47.8 Other spondylosis	0.993	0.007
M54 Dorsalgia	0.990	0.010
M51 Other intervertebral disk disorders	0.988	0.012
Chapter V Mental and behavioural disorders	0.985	0.015
M47.9 Spondylosis, unspecified	0.980	0.020
M54.5 Low back pain	0.979	0.021
M20-M25 Other joint disorders	0.979	0.021
M06 Other rheumatoid arthritis	0.978	0.022
M48 Other spondylopathies	0.975	0.025
Chapter II Neoplasms	0.970	0.030
G90-G99 Other disorders of the nervous system	0.967	0.033
Chapter IV Endocrine, nutritional and metabolic diseases	0.965	0.035
M06.9 Rheumatoid arthritis, unspecified	0.962	0.038
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.961	0.039
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.960	0.040
E00-E07 Disorders of thyroid gland	0.958	0.042
M47.82 Other spondylosis (Cervical region)	0.957	0.043
M48.0 Spinal stenosis	0.955	0.045
M54.57 Low back pain (Lumbosacral region)	0.950	0.050
E05 Thyrotoxicosis [hyperthyroidism]	0.948	0.052
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.944	0.056
S00-S09 Injuries to the head	0.937	0.063
M80-M85 Disorders of bone density and structure	0.935	0.065
E05.9 Thyrotoxicosis, unspecified	0.934	0.066
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.933	0.067
M51.2 Other specified intervertebral disk displacement	0.932	0.068
Chapter VII Diseases of the eye and adnexa	0.927	0.073
M20 Acquired deformities of fingers and toes	0.924	0.076
M40-M43 Deforming dorsopathies	0.923	0.077
M47.86 Other spondylosis (Lumbar region)	0.923	0.077
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.914	0.086
F17 Mental and behavioural disorders due to use of tobacco	0.912	0.088
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.906	0.094
M47.99 Spondylosis, unspecified (Site unspecified)	0.905	0.095
M20.1 Hallux valgus (acquired)	0.904	0.096
G99 Other disorders of nervous system in diseases classified elsewhere	0.903	0.097
C51-C58 Malignant neoplasms of female genital organs	0.898	0.102
M47.96 Spondylosis, unspecified (Lumbar region)	0.896	0.104
S00 Superficial injury of head	0.885	0.115
E20-E35 Disorders of other endocrine glands	0.884	0.116
M81 Osteoporosis without pathological fracture	0.882	0.118
S40-S49 Injuries to the shoulder and upper arm	0.880	0.120
C78.2 Secondary malignant neoplasm of pleura	0.876	0.124
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.876	0.124
F17.1 Harmful use	0.868	0.132
M54.59 Low back pain (Site unspecified)	0.868	0.132
S70-S79 Injuries to the hip and thigh	0.868	0.132
C78.0 Secondary malignant neoplasm of lung	0.867	0.133
M48.06 Spinal stenosis (Lumbar region)	0.862	0.138
M48.07 Spinal stenosis (Lumbosacral region)	0.859	0.141
F10 Mental and behavioural disorders due to use of alcohol	0.858	0.142
M25 Other joint disorders, not elsewhere classified	0.857	0.143
F40-F48 Neurotic, stress-related and somatoform disorders	0.853	0.147
M21 Other acquired deformities of limbs	0.852	0.148
G99.2 Myelopathy in diseases classified elsewhere	0.852	0.148
G20-G26 Extrapyramidal and movement disorders	0.851	0.149
Chapter XI Diseases of the digestive system	0.851	0.149
C79 Secondary malignant neoplasm of other sites	0.848	0.152
M47.87 Other spondylosis (Lumbosacral region)	0.846	0.154
M50 Cervical disk disorders	0.842	0.158
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.840	0.160
M47.92 Spondylosis, unspecified (Cervical region)	0.839	0.161
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.836	0.164
M31 Other necrotising vasculopathies	0.835	0.165
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.835	0.165
M43 Other deforming dorsopathies	0.833	0.167
M81.9 Osteoporosis, unspecified	0.832	0.168
K50-K52 Noninfective enteritis and colitis	0.831	0.169
E04 Other non-toxic goitre	0.831	0.169
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.828	0.171
C56 Malignant neoplasm of ovary	0.828	0.172
M54.9 Dorsalgia, unspecified	0.827	0.173
S60-S69 Injuries to the wrist and hand	0.825	0.175
S90-S99 Injuries to the ankle and foot	0.822	0.178
M10 Gout	0.821	0.179
M70-M79 Other soft tissue disorders	0.819	0.181
G50-G59 Nerve, nerve root and plexus disorders	0.819	0.181
K50 Crohn's disease [regional enteritis]	0.818	0.182
M51.8 Other specified intervertebral disk disorders	0.815	0.185
G95 Other diseases of spinal cord	0.815	0.185
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.814	0.186
Chapter XX External causes of morbidity and mortality	0.813	0.187
M05 Seropositive rheumatoid arthritis	0.810	0.190
T93 Sequelae of injuries of lower limb	0.810	0.190
M86-M90 Other osteopathies	0.810	0.190
M81.99 Osteoporosis, unspecified (Site unspecified)	0.809	0.191
D37-D48 Neoplasms of uncertain or unknown behaviour	0.809	0.191
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.808	0.192
M65-M68 Disorders of synovium and tendon	0.807	0.193
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.802	0.198
C15-C26 Malignant neoplasms of digestive organs	0.802	0.198
G00-G09 Inflammatory diseases of the central nervous system	0.801	0.199
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.799	0.201
M46 Other inflammatory spondylopathies	0.799	0.201
H04 Disorders of lachrymal system	0.796	0.204
S00.0 Superficial injury of scalp	0.794	0.206
H20 Iridocyclitis	0.791	0.209
M48.00 Spinal stenosis (Multiple sites in spine)	0.787	0.213
G91 Hydrocephalus	0.786	0.214
K50.9 Crohn's disease, unspecified	0.785	0.215
M24 Other specific joint derangements	0.783	0.217
G70-G73 Diseases of myoneural junction and muscle	0.781	0.218
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.781	0.219
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.780	0.220
E05.0 Thyrotoxicosis with diffuse goitre	0.779	0.221
M13 Other arthritis	0.776	0.223
M91-M94 Chondropathies	0.775	0.225
M20.2 Hallux rigidus	0.775	0.225
M47.1 Other spondylosis with myelopathy	0.773	0.227
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.773	0.227
M47.89 Other spondylosis (Site unspecified)	0.771	0.229
F43 Reaction to severe stress, and adjustment disorders	0.770	0.230
M43.1 Spondylolisthesis	0.769	0.231
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.767	0.232
S02 Fracture of skull and facial bones	0.766	0.234
M41 Scoliosis	0.765	0.235
T36-T50 Poisoning by drugs, medicaments and biological substances	0.763	0.237
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.762	0.238
M60-M63 Disorders of muscles	0.761	0.239
M48.09 Spinal stenosis (Site unspecified)	0.760	0.240
K13 Other diseases of lip and oral mucosa	0.760	0.240
M06.4 Inflammatory polyarthropathy	0.759	0.241
E04.2 Non-toxic multinodular goitre	0.759	0.241
F80-F89 Disorders of psychological development	0.758	0.242
F10.4 Withdrawal state with delirium	0.755	0.245
F10.3 Withdrawal state	0.755	0.245
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.754	0.246
M51.9 Intervertebral disk disorder, unspecified	0.752	0.248
S50-S59 Injuries to the elbow and forearm	0.750	0.250
E03 Other hypothyroidism	0.749	0.251
E27 Other disorders of adrenal gland	0.748	0.252
S09 Other and unspecified injuries of head	0.747	0.253
C55 Malignant neoplasm of uterus, part unspecified	0.746	0.254
G35-G37 Demyelinating diseases of the central nervous system	0.745	0.255
S72 Fracture of femur	0.744	0.255
M34 Systemic sclerosis	0.744	0.256
M06.0 Seronegative rheumatoid arthritis	0.742	0.258
G93 Other disorders of brain	0.742	0.258
M50.0 Cervical disk disorder with myelopathy	0.742	0.258
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.741	0.258
M47.2 Other spondylosis with radiculopathy	0.740	0.259
S06 Intracranial injury	0.740	0.260
G40-G47 Episodic and paroxysmal disorders	0.740	0.260
K11 Diseases of salivary glands	0.739	0.261
T92 Sequelae of injuries of upper limb	0.738	0.262
M54.3 Sciatica	0.737	0.262
T66-T78 Other and unspecified effects of external causes	0.736	0.264
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.735	0.265
G25 Other extrapyramidal and movement disorders	0.735	0.265
H21 Other disorders of iris and ciliary body	0.734	0.266
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.733	0.266
C15 Malignant neoplasm of oesophagus	0.733	0.267
M48.5 Collapsed vertebra, not elsewhere classified	0.733	0.267
S10-S19 Injuries to the neck	0.732	0.267
C79.8 Secondary malignant neoplasm of other specified sites	0.732	0.268
M54.6 Pain in thoracic spine	0.732	0.268
H04.5 Stenosis and insufficiency of lachrymal passages	0.732	0.268
H20.9 Iridocyclitis, unspecified	0.730	0.270
S00.1 Contusion of eyelid and periocular area	0.729	0.271
K52 Other non-infective gastro-enteritis and colitis	0.728	0.272
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.727	0.273
T93.2 Sequelae of other fractures of lower limb	0.727	0.273
M31.6 Other giant cell arteritis	0.725	0.275
F99-F99 Unspecified mental disorder	0.725	0.275
M00-M03 Infectious arthropathies	0.725	0.275
M79 Other soft tissue disorders, not elsewhere classified	0.724	0.276
M54.50 Low back pain (Multiple sites in spine)	0.723	0.277
M07 Psoriatic and enteropathic arthropathies	0.721	0.279
E50-E64 Other nutritional deficiencies	0.720	0.280
M84 Disorders of continuity of bone	0.720	0.280
S00.8 Superficial injury of other parts of head	0.719	0.281
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.718	0.282
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
M49 Spondylopathies in diseases classified elsewhere	0.717	0.283
M53 Other dorsopathies, not elsewhere classified	0.717	0.283
M47.0 Anterior spinal and vertebral artery compression syndromes	0.717	0.283
S67 Crushing injury of wrist and hand	0.716	0.283
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.715	0.285
M54.4 Lumbago with sciatica	0.715	0.285
T79-T79 Certain early complications of trauma	0.714	0.286
T33-T35 Frostbite	0.714	0.286
T26-T28 Burns and corrosions confined to eye and internal organs	0.714	0.286
T20-T25 Burns and corrosions of external body surface, specified by site	0.714	0.286
T00-T07 Injuries involving multiple body regions	0.714	0.286
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.714	0.286
C80 Malignant neoplasm without specification of site	0.714	0.286
F17.2 Dependence syndrome	0.712	0.288
M14 Arthropathies in other diseases classified elsewhere	0.712	0.288
M12 Other specific arthropathies	0.712	0.288
M09 Juvenile arthritis in diseases classified elsewhere	0.712	0.288
M08 Juvenile arthritis	0.712	0.288
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.712	0.288
M47.85 Other spondylosis (Thoracolumbar region)	0.712	0.288
M47.84 Other spondylosis (Thoracic region)	0.712	0.288
M47.83 Other spondylosis (Cervicothoracic region)	0.712	0.288
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.712	0.288
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.712	0.288
M43.16 Spondylolisthesis (Lumbar region)	0.711	0.289
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.711	0.289
M82 Osteoporosis in diseases classified elsewhere	0.710	0.290
M54.8 Other dorsalgia	0.710	0.290
M54.0 Panniculitis affecting regions of neck and back	0.710	0.290
M20.0 Deformity of finger(s)	0.710	0.290
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.709	0.291
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.709	0.291
M51.3 Other specified intervertebral disk degeneration	0.708	0.292
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.708	0.292
M51.4 Schmorl's nodes	0.708	0.292
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.706	0.294
F70-F79 Mental retardation	0.706	0.294
S42 Fracture of shoulder and upper arm	0.703	0.297
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)	0.703	0.297
M47.95 Spondylosis, unspecified (Thoracolumbar region)	0.703	0.297
M47.94 Spondylosis, unspecified (Thoracic region)	0.703	0.297
M47.93 Spondylosis, unspecified (Cervicothoracic region)	0.703	0.297
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)	0.703	0.297
K13.7 Other and unspecified lesions of oral mucosa	0.703	0.297
M54.55 Low back pain (Thoracolumbar region)	0.702	0.298
M54.54 Low back pain-Thoracic	0.702	0.298
M54.53 Low back pain-Cervicothoracic	0.702	0.298
M54.52 Low back pain-Cervical	0.702	0.298
M54.51 Low back pain-Occipit-atl-axl	0.702	0.298
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.702	0.298
M33 Dermatopolymyositis	0.702	0.298
M32 Systemic lupus erythematosus	0.702	0.298
M30 Polyarteritis nodosa and related conditions	0.702	0.298
M06.8 Other specified rheumatoid arthritis	0.701	0.299
M06.3 Rheumatoid nodule	0.701	0.299
M06.2 Rheumatoid bursitis	0.701	0.299
M06.1 Adult-onset Still's disease	0.701	0.299
C60-C63 Malignant neoplasms of male genital organs	0.701	0.299
T90 Sequelae of injuries of head	0.700	0.300
M65 Synovitis and tenosynovitis	0.699	0.301
M48.9 Spondylopathy, unspecified	0.699	0.301
M48.8 Other specified spondylopathies	0.699	0.301
M48.4 Fatigue fracture of vertebra	0.699	0.301
M48.3 Traumatic spondylopathy	0.699	0.301
M48.2 Kissing spine	0.699	0.301
M48.1 Ankylosing hyperostosis [Forestier]	0.699	0.301
E06 Thyroiditis	0.699	0.301
S40 Superficial injury of shoulder and upper arm	0.699	0.301
M10.9 Gout, unspecified	0.698	0.302
Chapter XXII Codes for special purposes	0.697	0.303
C19 Malignant neoplasm of rectosigmoid junction	0.697	0.303
W20-W49 Exposure to inanimate mechanical forces	0.696	0.304
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.696	0.304
C40-C41 Malignant neoplasms of bone and articular cartilage	0.696	0.304
K01 Embedded and impacted teeth	0.695	0.305
M48.02 Spinal stenosis (Cervical region)	0.695	0.305
C78.7 Secondary malignant neoplasm of liver	0.695	0.305
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.693	0.307
G96 Other disorders of central nervous system	0.693	0.307
G94 Other disorders of brain in diseases classified elsewhere	0.693	0.307
G90 Disorders of autonomic nervous system	0.693	0.307
G98 Other disorders of nervous system, not elsewhere classified	0.693	0.307
G92 Toxic encephalopathy	0.693	0.307
K50.0 Crohn's disease of small intestine	0.693	0.307
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.692	0.307
E40-E46 Malnutrition	0.692	0.308
H55-H59 Other disorders of eye and adnexa	0.692	0.308
F60-F69 Disorders of adult personality and behaviour	0.690	0.310
M06.98 Rheumatoid arthritis, unspecified (Other)	0.689	0.310
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.689	0.310
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.689	0.310
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.689	0.310
M54.99 Dorsalgia, unspecified (Site unspecified)	0.690	0.310
C76 Malignant neoplasm of other and ill-defined sites	0.689	0.311
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.688	0.312
F18 Mental and behavioural disorders due to use of volatile solvents	0.688	0.312
F16 Mental and behavioural disorders due to use of hallucinogens	0.688	0.312
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.688	0.312
F14 Mental and behavioural disorders due to use of cocaine	0.688	0.312
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.688	0.312
F12 Mental and behavioural disorders due to use of cannabinoids	0.688	0.312
F11 Mental and behavioural disorders due to use of opioids	0.688	0.312
C83 Diffuse non-Hodgkin's lymphoma	0.688	0.312
M81.4 Drug-induced osteoporosis	0.688	0.312
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.687	0.313
E00 Congenital iodine-deficiency syndrome	0.687	0.313
E02 Subclinical iodine-deficiency hypothyroidism	0.687	0.313
M21.4 Flat foot [pes planus] (acquired)	0.687	0.313
M54.1 Radiculopathy	0.686	0.314
M25.8 Other specified joint disorders	0.685	0.315
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.685	0.315
M48.05 Spinal stenosis (Thoracolumbar region)	0.685	0.315
M48.04 Spinal stenosis (Thoracic region)	0.685	0.315
M48.03 Spinal stenosis (Cervicothoracic region)	0.685	0.315
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.685	0.315
K05 Gingivitis and periodontal diseases	0.684	0.316
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.684	0.316
E23 Hypofunction and other disorders of pituitary gland	0.684	0.316
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.683	0.317
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.682	0.318
F45 Somatoform disorders	0.682	0.318
S41 Open wound of shoulder and upper arm	0.681	0.319
H52 Disorders of refraction and accommodation	0.681	0.319
E05.8 Other thyrotoxicosis	0.680	0.320
E05.5 Thyroid crisis or storm	0.680	0.320
E05.4 Thyrotoxicosis factitia	0.680	0.320
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.680	0.320
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.680	0.320
M05.9 Seropositive rheumatoid arthritis, unspecified	0.680	0.320
Q20-Q28 Congenital malformations of the circulatory system	0.680	0.320
G95.9 Disease of spinal cord, unspecified	0.678	0.321
C64-C68 Malignant neoplasms of urinary tract	0.678	0.322
H18 Other disorders of cornea	0.678	0.322
M21.0 Valgus deformity, not elsewhere classified	0.677	0.323
C78.4 Secondary malignant neoplasm of small intestine	0.677	0.323
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.677	0.323
C78.1 Secondary malignant neoplasm of mediastinum	0.677	0.323
E24 Cushing's syndrome	0.677	0.323
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.676	0.324
H04.1 Other disorders of lachrymal gland	0.676	0.324
M25.5 Pain in joint	0.676	0.324
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.675	0.325
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.675	0.325
C79.9 Secondary malignant neoplasm, unspecified site	0.674	0.326
S08 Traumatic amputation of part of head	0.672	0.328
S07 Crushing injury of head	0.672	0.328
S05 Injury of eye and orbit	0.672	0.328
S04 Injury of cranial nerves	0.672	0.328
S03 Dislocation, sprain and strain of joints and ligaments of head	0.672	0.328
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.672	0.328
M11 Other crystal arthropathies	0.671	0.329
M83 Adult osteomalacia	0.671	0.329
G30-G32 Other degenerative diseases of the nervous system	0.670	0.329
Chapter XIV Diseases of the genitourinary system	0.670	0.330
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.670	0.330
S70 Superficial injury of hip and thigh	0.669	0.330
M50.1 Cervical disk disorder with radiculopathy	0.668	0.332
M79.6 Pain in limb	0.667	0.333
S00.3 Superficial injury of nose	0.667	0.333
E22 Hyperfunction of pituitary gland	0.666	0.334
F40 Phobic anxiety disorders	0.666	0.334
E29 Testicular dysfunction	0.666	0.334
H46-H48 Disorders of optic nerve and visual pathways	0.665	0.335
M25.6 Stiffness of joint, not elsewhere classified	0.665	0.335
S71 Open wound of hip and thigh	0.664	0.336
K07 Dentofacial anomalies [including malocclusion]	0.664	0.336
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.663	0.337
K35-K38 Diseases of appendix	0.663	0.337
F43.1 Posttraumatic stress disorder	0.662	0.338
M42 Spinal osteochondrosis	0.662	0.338
M40 Kyphosis and lordosis	0.662	0.338
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.662	0.338
S30 Superficial injury of abdomen, lower back and pelvis	0.661	0.339
M54.2 Cervicalgia	0.660	0.340
G80-G83 Cerebral palsy and other paralytic syndromes	0.660	0.340
S92 Fracture of foot, except ankle	0.659	0.341
K50.1 Crohn's disease of large intestine	0.658	0.342
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.657	0.343
C53 Malignant neoplasm of cervix uteri	0.657	0.343
T98 Sequelae of other and unspecified effects of external causes	0.655	0.344
T95 Sequelae of burns, corrosions and frostbite	0.655	0.344
T94 Sequelae of injuries involving multiple and unspecified body regions	0.655	0.344
T91 Sequelae of injuries of neck and trunk	0.655	0.344
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.655	0.344
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.655	0.344
M21.1 Varus deformity, not elsewhere classified	0.655	0.344
C15.9 Oesophagus, unspecified	0.655	0.345
G58 Other mononeuropathies	0.655	0.345
N40-N51 Diseases of male genital organs	0.655	0.345
N10-N16 Renal tubulo-interstitial diseases	0.654	0.346
M46.9 Inflammatory spondylopathy, unspecified	0.654	0.346
F17.9 Unspecified mental and behavioural disorder	0.654	0.346
F17.8 Other mental and behavioural disorders	0.654	0.346
F17.7 Residual and late-onset psychotic disorder	0.654	0.346
F17.6 Amnesic syndrome	0.654	0.346
F17.5 Psychotic disorder	0.654	0.346
F17.4 Withdrawal state with delirium	0.654	0.346
F17.3 Withdrawal state	0.654	0.346
F17.0 Acute intoxication	0.654	0.346
Q00-Q07 Congenital malformations of the nervous system	0.653	0.346
C16 Malignant neoplasm of stomach	0.653	0.346
M25.0 Haemarthrosis	0.653	0.347
M54.56 Low back pain (Lumbar region)	0.653	0.347
M80 Osteoporosis with pathological fracture	0.651	0.349
M41.9 Scoliosis, unspecified	0.651	0.349
S72.0 Fracture of neck of femur	0.651	0.349
F43.0 Acute stress reaction	0.650	0.349
G45 Transient cerebral ischaemic attacks and related syndromes	0.650	0.350
S60 Superficial injury of wrist and hand	0.649	0.351
K00 Disorders of tooth development and eruption	0.649	0.351
S32 Fracture of lumbar spine and pelvis	0.649	0.351
M87 Osteonecrosis	0.649	0.351
G99.8 Other specified disorders of nervous system in diseases classified elsewhere	0.647	0.352
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere	0.647	0.352
H10-H13 Disorders of conjunctiva	0.646	0.354
S49 Other and unspecified injuries of shoulder and upper arm	0.646	0.354
K10 Other diseases of jaws	0.645	0.355
M54.94 Dorsalgia, unspecified (Thoracic region)	0.645	0.355
C02 Malignant neoplasm of other and unspecified parts of tongue	0.644	0.356
C57 Malignant neoplasm of other and unspecified female genital organs	0.644	0.356
C51 Malignant neoplasm of vulva	0.644	0.356
C58 Malignant neoplasm of placenta	0.644	0.356
C52 Malignant neoplasm of vagina	0.644	0.356
M25.9 Joint disorder, unspecified	0.644	0.356
D45 Polycythaemia vera	0.643	0.357
F30-F39 Mood [affective] disorders	0.643	0.357
H43-H45 Disorders of vitreous body and globe	0.642	0.358
H16 Keratitis	0.642	0.358
K09 Cysts of oral region, not elsewhere classified	0.641	0.359
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.641	0.359
M54.39 Sciatica (Site unspecified)	0.641	0.359
Y43 Primarily systemic agents	0.641	0.359
Chapter VIII Diseases of the ear and mastoid process	0.641	0.359
S99 Other and unspecified injuries of ankle and foot	0.639	0.360
S20-S29 Injuries to the thorax	0.639	0.361
S67.0 Crushing injury of thumb and other finger(s)	0.639	0.361
G20 Parkinson's disease	0.638	0.362
G25.8 Other specified extrapyramidal and movement disorders	0.637	0.363
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.637	0.363
E28 Ovarian dysfunction	0.636	0.364
H05 Disorders of orbit	0.635	0.365
S00.7 Multiple superficial injuries of head	0.635	0.365
S00.5 Superficial injury of lip and oral cavity	0.635	0.365
S00.4 Superficial injury of ear	0.635	0.365
S00.2 Other superficial injuries of eyelid and periocular area	0.635	0.365
N13 Obstructive and reflux uropathy	0.635	0.365
G55.0 Nerve root and plexus compressions in neoplastic disease	0.634	0.366
E35 Disorders of endocrine glands in diseases classified elsewhere	0.634	0.366
E34 Other endocrine disorders	0.634	0.366
E32 Diseases of thymus	0.634	0.366
E31 Polyglandular dysfunction	0.634	0.366
E30 Disorders of puberty, not elsewhere classified	0.634	0.366
E26 Hyperaldosteronism	0.634	0.366
E25 Adrenogenital disorders	0.634	0.366
E20 Hypoparathyroidism	0.634	0.366
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.633	0.367
M25.7 Osteophyte	0.633	0.367
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.632	0.368
M81.8 Other osteoporosis	0.632	0.368
M81.6 Localised osteoporosis [Lequesne]	0.632	0.368
M81.5 Idiopathic osteoporosis	0.632	0.368
M81.3 Postsurgical malabsorption osteoporosis	0.632	0.368
M81.2 Osteoporosis of disuse	0.632	0.368
M81.1 Postoophorectomy osteoporosis	0.632	0.368
M81.0 Postmenopausal osteoporosis	0.632	0.368
M45 Ankylosing spondylitis	0.632	0.368
G95.2 Cord compression, unspecified	0.631	0.369
K50.8 Other Crohn's disease	0.631	0.369
S48 Traumatic amputation of shoulder and upper arm	0.631	0.369
S46 Injury of muscle and tendon at shoulder and upper arm level	0.631	0.369
S45 Injury of blood vessels at shoulder and upper arm level	0.631	0.369
S44 Injury of nerves at shoulder and upper arm level	0.631	0.369
S47 Crushing injury of shoulder and upper arm	0.631	0.369
F00-F09 Organic, including symptomatic, mental disorders	0.630	0.370
G70 Myasthenia gravis and other myoneural disorders	0.629	0.371
F43.9 Reaction to severe stress, unspecified	0.629	0.371
N48 Other disorders of penis	0.629	0.371
M85 Other disorders of bone density and structure	0.628	0.371
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.628	0.372
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.628	0.372
H17 Corneal scars and opacities	0.628	0.372
H15 Disorders of sclera	0.628	0.372
D46 Myelodysplastic syndromes	0.628	0.372
F42 Obsessive-compulsive disorder	0.628	0.372
G03 Meningitis due to other and unspecified causes	0.627	0.373
G91.9 Hydrocephalus, unspecified	0.625	0.375
Q60-Q64 Congenital malformations of the urinary system	0.624	0.376
S02.4 Fracture of malar and maxillary bones	0.624	0.376
V80-V89 Other land transport accidents	0.624	0.376
M47.80 Other spondylosis (Multiple sites in spine)	0.623	0.377
K12 Stomatitis and related lesions	0.622	0.377
M77 Other enthesopathies	0.622	0.377
S78 Traumatic amputation of hip and thigh	0.622	0.378
S77 Crushing injury of hip and thigh	0.622	0.378
S76 Injury of muscle and tendon at hip and thigh level	0.622	0.378
S75 Injury of blood vessels at hip and thigh level	0.622	0.378
S74 Injury of nerves at hip and thigh level	0.622	0.378
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.622	0.378
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere	0.622	0.378
K52.8 Other specified non-infective gastro-enteritis and colitis	0.621	0.379
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.620	0.379
G04 Encephalitis, myelitis and encephalomyelitis	0.620	0.380
M24.8 Other specific joint derangements, not elsewhere classified	0.620	0.380
H21.5 Other adhesions and disruptions of iris and ciliary body	0.618	0.382
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.618	0.382
K08 Other disorders of teeth and supporting structures	0.618	0.382
E04.1 Non-toxic single thyroid nodule	0.617	0.383
M24.2 Disorder of ligament	0.616	0.384
M31.3 Wegener's granulomatosis	0.615	0.385
F10.9 Unspecified mental and behavioural disorder	0.615	0.385
F10.8 Other mental and behavioural disorders	0.615	0.385
F10.7 Residual and late-onset psychotic disorder	0.615	0.385
F10.6 Amnesic syndrome	0.615	0.385
F10.5 Psychotic disorder	0.615	0.385
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.614	0.386
M25.3 Other instability of joint	0.614	0.386
M25.2 Flail joint	0.614	0.386
M25.1 Fistula of joint	0.614	0.386
F10.2 Dependence syndrome	0.613	0.387

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations