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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74968339
log Bayes Factor = 14.8939
Chromosome 18   position 52,753,199  (GRCh37) Explore rs74968339 on Ensembl!
Variant rs74968339 is part of Cluster X0030

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
0.999 0.001 0.000
E11 Non-insulin-dependent diabetes mellitus
0.996 0.004 0.000
Chapter II Neoplasms
0.996 0.004 0.000
I60-I69 Cerebrovascular diseases
0.994 0.006 0.000
E10 Insulin-dependent diabetes mellitus
0.988 0.012 0.000
I20 Angina pectoris
0.986 0.014 0.000
Chapter XX External causes of morbidity and mortality
0.984 0.016 0.000
C15-C26 Malignant neoplasms of digestive organs
0.983 0.017 0.000
S60-S69 Injuries to the wrist and hand
0.977 0.023 0.000
Chapter XI Diseases of the digestive system
0.977 0.023 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.976 0.024 0.000
I20.0 Unstable angina
0.976 0.024 0.000
Chapter I Certain infectious and parasitic diseases
0.976 0.024 0.000
K70-K77 Diseases of liver
0.974 0.026 0.000
E10.9 Without complications
0.967 0.033 0.000
K70 Alcoholic liver disease
0.960 0.040 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.958 0.042 0.000
B95-B98 Bacterial, viral and other infectious agents
0.957 0.043 0.000
C25 Malignant neoplasm of pancreas
0.957 0.043 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.956 0.044 0.000
I25 Chronic ischaemic heart disease
0.955 0.045 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.950 0.050 0.000
S20-S29 Injuries to the thorax
0.948 0.052 0.000
E11.4 With neurological complications
0.944 0.056 0.000
I80 Phlebitis and thrombophlebitis
0.941 0.059 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.936 0.064 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.936 0.064 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.929 0.071 0.000
Chapter XXI Factors influencing health status and contact with health services
0.929 0.071 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.927 0.073 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.924 0.076 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.923 0.077 0.000
S61 Open wound of wrist and hand
0.912 0.088 0.000
K70.9 Alcoholic liver disease, unspecified
0.912 0.088 0.000
E11.9 Without complications
0.909 0.091 0.000
Chapter X Diseases of the respiratory system
0.908 0.092 0.000
C18 Malignant neoplasm of colon
0.906 0.094 0.000
E20-E35 Disorders of other endocrine glands
0.905 0.095 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.905 0.095 0.000
K50-K52 Noninfective enteritis and colitis
0.904 0.096 0.000
C25.0 Head of pancreas
0.898 0.102 0.000
J09-J18 Influenza and pneumonia
0.897 0.103 0.000
I63 Cerebral infarction
0.897 0.103 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.891 0.109 0.000
I26 Pulmonary embolism
0.889 0.111 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.886 0.114 0.000
I69 Sequelae of cerebrovascular disease
0.886 0.114 0.000
J18 Pneumonia, organism unspecified
0.884 0.116 0.000
K86 Other diseases of pancreas
0.882 0.118 0.000
Z72 Problems related to lifestyle
0.881 0.119 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.879 0.121 0.000
W20-W49 Exposure to inanimate mechanical forces
0.874 0.126 0.000
I21 Acute myocardial infarction
0.874 0.126 0.000
C25.9 Pancreas, unspecified
0.872 0.128 0.000
I60 Subarachnoid haemorrhage
0.871 0.129 0.000
S20 Superficial injury of thorax
0.870 0.130 0.000
S80-S89 Injuries to the knee and lower leg
0.868 0.132 0.000
E11.3 With ophthalmic complications
0.863 0.137 0.000
Z72.1 Alcohol use
0.863 0.137 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.862 0.138 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.858 0.142 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.858 0.142 0.000
Chapter VIII Diseases of the ear and mastoid process
0.856 0.144 0.000
I25.2 Old myocardial infarction
0.856 0.144 0.000
S90-S99 Injuries to the ankle and foot
0.854 0.146 0.000
J18.1 Lobar pneumonia, unspecified
0.854 0.146 0.000
S50-S59 Injuries to the elbow and forearm
0.854 0.146 0.000
K76 Other diseases of liver
0.853 0.147 0.000
I71 Aortic aneurysm and dissection
0.853 0.147 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.852 0.148 0.000
K74 Fibrosis and cirrhosis of liver
0.848 0.152 0.000
K51 Ulcerative colitis
0.847 0.153 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.844 0.156 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.842 0.158 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.841 0.159 0.000
C15 Malignant neoplasm of oesophagus
0.839 0.161 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.834 0.166 0.000
Chapter VI Diseases of the nervous system
0.832 0.168 0.000
K70.3 Alcoholic cirrhosis of liver
0.830 0.170 0.000
I24 Other acute ischaemic heart diseases
0.830 0.170 0.000
I10-I15 Hypertensive diseases
0.829 0.171 0.000
E70-E90 Metabolic disorders
0.828 0.172 0.000
I27 Other pulmonary heart diseases
0.826 0.174 0.000
I20.1 Angina pectoris with documented spasm
0.826 0.174 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.826 0.174 0.000
B35-B49 Mycoses
0.826 0.174 0.000
S40-S49 Injuries to the shoulder and upper arm
0.824 0.176 0.000
O30 Multiple gestation
0.824 0.176 0.000
E10.1 With ketoacidosis
0.823 0.177 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.823 0.177 0.000
C77.5 Intrapelvic lymph nodes
0.823 0.177 0.000
E11.2 With renal complications
0.820 0.180 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.820 0.180 0.000
E50-E64 Other nutritional deficiencies
0.819 0.181 0.000
J18.9 Pneumonia, unspecified
0.819 0.181 0.000
K83 Other diseases of biliary tract
0.818 0.182 0.000
C77.2 Intra-abdominal lymph nodes
0.810 0.190 0.000
C64-C68 Malignant neoplasms of urinary tract
0.810 0.190 0.000
I82 Other venous embolism and thrombosis
0.810 0.190 0.000
S61.0 Open wound of finger(s) without damage to nail
0.808 0.192 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.808 0.192 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.807 0.193 0.000
I61 Intracerebral haemorrhage
0.806 0.194 0.000
C18.9 Colon, unspecified
0.805 0.195 0.000
I62 Other nontraumatic intracranial haemorrhage
0.804 0.196 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.804 0.196 0.000
E10.3 With ophthalmic complications
0.803 0.197 0.000
S20.8 Superficial injuries of other and unspecified parts of thorax
0.799 0.201 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.799 0.201 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.797 0.203 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.797 0.203 0.000
E11.6 With other specified complications
0.795 0.205 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.795 0.205 0.000
K85 Acute pancreatitis
0.795 0.205 0.000
Y44 Agents primarily affecting blood constituents
0.794 0.206 0.000
K70.1 Alcoholic hepatitis
0.790 0.210 0.000
I77 Other disorders of arteries and arterioles
0.790 0.210 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.789 0.211 0.000
E11.5 With peripheral circulatory complications
0.788 0.212 0.000
V20-V29 Motorcycle rider injured in transport accident
0.788 0.212 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.788 0.212 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.787 0.213 0.000
I63.9 Cerebral infarction, unspecified
0.787 0.213 0.000
K82 Other diseases of gallbladder
0.786 0.214 0.000
S62 Fracture at wrist and hand level
0.784 0.216 0.000
K76.6 Portal hypertension
0.783 0.217 0.000
O42 Premature rupture of membranes
0.782 0.218 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.782 0.218 0.000
I88 Nonspecific lymphadenitis
0.780 0.220 0.000
C77.9 Lymph node, unspecified
0.779 0.221 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.779 0.221 0.000
K86.1 Other chronic pancreatitis
0.778 0.222 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.777 0.223 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.774 0.226 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.774 0.226 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.773 0.227 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.772 0.228 0.000
K74.6 Other and unspecified cirrhosis of liver
0.771 0.229 0.000
K70.4 Alcoholic hepatic failure
0.770 0.230 0.000
S70-S79 Injuries to the hip and thigh
0.769 0.231 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.769 0.231 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.765 0.235 0.000
B15-B19 Viral hepatitis
0.765 0.235 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.764 0.235 0.000
E13 Other specified diabetes mellitus
0.764 0.236 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.764 0.236 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.764 0.236 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.763 0.237 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.762 0.237 0.000
C51-C58 Malignant neoplasms of female genital organs
0.762 0.238 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.762 0.238 0.000
S68 Traumatic amputation of wrist and hand
0.761 0.239 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.760 0.240 0.000
O85-O92 Complications predominantly related to the puerperium
0.760 0.240 0.000
Z03.4 Observation for suspected myocardial infarction
0.760 0.240 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.759 0.241 0.000
I22 Subsequent myocardial infarction
0.758 0.242 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.758 0.242 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.757 0.243 0.000
S61.1 Open wound of finger(s) with damage to nail
0.756 0.244 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.755 0.245 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.753 0.247 0.000
I25.3 Aneurysm of heart
0.753 0.247 0.000
A80-A89 Viral infections of the central nervous system
0.752 0.248 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.752 0.248 0.000
T79-T79 Certain early complications of trauma
0.752 0.248 0.000
H90-H95 Other disorders of ear
0.751 0.249 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.751 0.249 0.000
O30.0 Twin pregnancy
0.750 0.250 0.000
C78.0 Secondary malignant neoplasm of lung
0.750 0.250 0.000
K83.1 Obstruction of bile duct
0.749 0.251 0.000
Z73 Problems related to life-management difficulty
0.746 0.254 0.000
K72 Hepatic failure, not elsewhere classified
0.745 0.255 0.000
Y57 Other and unspecified drugs and medicaments
0.744 0.256 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.743 0.257 0.000
S64 Injury of nerves at wrist and hand level
0.741 0.259 0.000
T18 Foreign body in alimentary tract
0.740 0.260 0.000
I70 Atherosclerosis
0.739 0.261 0.000
C21 Malignant neoplasm of anus and anal canal
0.739 0.261 0.000
C44 Other malignant neoplasms of skin
0.738 0.262 0.000
W44 Foreign body entering into or through eye or natural orifice
0.738 0.262 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.737 0.263 0.000
S10-S19 Injuries to the neck
0.736 0.264 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.736 0.264 0.000
Chapter XXII Codes for special purposes
0.734 0.266 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.733 0.267 0.000
H60-H62 Diseases of external ear
0.733 0.267 0.000
E27 Other disorders of adrenal gland
0.732 0.268 0.000
K86.0 Alcohol-induced chronic pancreatitis
0.732 0.268 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.732 0.268 0.000
Y84.8 Other medical procedures
0.732 0.268 0.000
C18.4 Transverse colon
0.731 0.269 0.000
E23 Hypofunction and other disorders of pituitary gland
0.731 0.269 0.000
K75 Other inflammatory liver diseases
0.729 0.270 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.729 0.271 0.000
S90 Superficial injury of ankle and foot
0.729 0.271 0.000
I27.0 Primary pulmonary hypertension
0.729 0.271 0.000
C78.2 Secondary malignant neoplasm of pleura
0.728 0.272 0.000
I87 Other disorders of veins
0.727 0.272 0.000
K51.8 Other ulcerative colitis
0.726 0.274 0.000
C77.4 Inguinal and lower limb lymph nodes
0.726 0.274 0.000
I69.3 Sequelae of cerebral infarction
0.719 0.281 0.000
I85 Oesophageal varices
0.719 0.281 0.000
B37 Candidiasis
0.718 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S61.8 Open wound of other parts of wrist and hand
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.716 0.283 0.000
C15.9 Oesophagus, unspecified
0.716 0.284 0.000
S60 Superficial injury of wrist and hand
0.716 0.284 0.000
Y52 Agents primarily affecting the cardiovascular system
0.716 0.284 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.715 0.285 0.000
O36 Maternal care for other known or suspected foetal problems
0.714 0.285 0.000
E24 Cushing's syndrome
0.714 0.286 0.000
E11.8 With unspecified complications
0.714 0.286 0.000
E11.7 With multiple complications
0.714 0.286 0.000
E11.1 With ketoacidosis
0.714 0.286 0.000
E11.0 With coma
0.714 0.286 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.714 0.286 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.714 0.286 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.714 0.286 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.714 0.286 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.714 0.286 0.000
Z72.2 Drug use
0.713 0.287 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.713 0.287 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.713 0.287 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.712 0.288 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.712 0.288 0.000
Y84.2 Radiological procedure and radiotherapy
0.712 0.288 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.711 0.288 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.711 0.289 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.711 0.289 0.000
S51 Open wound of forearm
0.711 0.289 0.000
C18.5 Splenic flexure
0.709 0.291 0.000
I71.0 Dissection of aorta [any part]
0.709 0.291 0.000
I67 Other cerebrovascular diseases
0.709 0.291 0.000
E10.8 With unspecified complications
0.708 0.291 0.000
E10.7 With multiple complications
0.708 0.291 0.000
E10.6 With other specified complications
0.708 0.291 0.000
E10.5 With peripheral circulatory complications
0.708 0.291 0.000
E10.2 With renal complications
0.708 0.291 0.000
E10.0 With coma
0.708 0.291 0.000
O41 Other disorders of amniotic fluid and membranes
0.708 0.292 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.706 0.293 0.000
C16 Malignant neoplasm of stomach
0.706 0.293 0.000
C77.8 Lymph nodes of multiple regions
0.706 0.294 0.000
J14 Pneumonia due to Haemophilus influenzae
0.706 0.294 0.000
K86.3 Pseudocyst of pancreas
0.706 0.294 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.705 0.295 0.000
Y35-Y36 Legal intervention and operations of war
0.705 0.295 0.000
Y10-Y34 Event of undetermined intent
0.705 0.295 0.000
Y00-Y09 Assault
0.705 0.295 0.000
X85-X99 Assault
0.705 0.295 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.705 0.295 0.000
X50-X57 Overexertion, travel and privation
0.705 0.295 0.000
X30-X39 Exposure to forces of nature
0.705 0.295 0.000
X20-X29 Contact with venomous animals and plants
0.705 0.295 0.000
X10-X19 Contact with heat and hot substances
0.705 0.295 0.000
X00-X09 Exposure to smoke, fire and flames
0.705 0.295 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.705 0.295 0.000
W75-W84 Other accidental threats to breathing
0.705 0.295 0.000
W65-W74 Accidental drowning and submersion
0.705 0.295 0.000
W50-W64 Exposure to animate mechanical forces
0.705 0.295 0.000
V98-V99 Other and unspecified transport accidents
0.705 0.295 0.000
V95-V97 Air and space transport accidents
0.705 0.295 0.000
V90-V94 Water transport accidents
0.705 0.295 0.000
V80-V89 Other land transport accidents
0.705 0.295 0.000
V70-V79 Bus occupant injured in transport accident
0.705 0.295 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.705 0.295 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.705 0.295 0.000
V40-V49 Car occupant injured in transport accident
0.705 0.295 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.705 0.295 0.000
V01-V09 Pedestrian injured in transport accident
0.705 0.295 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.705 0.295 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.705 0.295 0.000
C17 Malignant neoplasm of small intestine
0.705 0.295 0.000
C23 Malignant neoplasm of gallbladder
0.705 0.295 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.705 0.295 0.000
S61.7 Multiple open wounds of wrist and hand
0.705 0.295 0.000
E40-E46 Malnutrition
0.704 0.295 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.704 0.296 0.000
S27 Injury of other and unspecified intrathoracic organs
0.704 0.296 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.704 0.296 0.000
C67 Malignant neoplasm of bladder
0.704 0.296 0.000
T86 Failure and rejection of transplanted organs and tissues
0.704 0.296 0.000
I82.8 Embolism and thrombosis of other specified veins
0.704 0.296 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.703 0.297 0.000
A30-A49 Other bacterial diseases
0.703 0.297 0.000
E10.4 With neurological complications
0.703 0.297 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.702 0.298 0.000
O60-O75 Complications of labour and delivery
0.701 0.299 0.000
S67 Crushing injury of wrist and hand
0.701 0.299 0.000
S65 Injury of blood vessels at wrist and hand level
0.701 0.299 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.700 0.300 0.000
B99-B99 Other infectious diseases
0.700 0.300 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.700 0.300 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.700 0.300 0.000
B65-B83 Helminthiases
0.700 0.300 0.000
B50-B64 Protozoal diseases
0.700 0.300 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.700 0.300 0.000
A75-A79 Rickettsioses
0.700 0.300 0.000
A70-A74 Other diseases caused by chlamydiae
0.700 0.300 0.000
A65-A69 Other spirochaetal diseases
0.700 0.300 0.000
A20-A28 Certain zoonotic bacterial diseases
0.700 0.300 0.000
A15-A19 Tuberculosis
0.700 0.300 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.700 0.300 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.699 0.300 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.699 0.301 0.000
K77 Liver disorders in diseases classified elsewhere
0.698 0.301 0.000
K73 Chronic hepatitis, not elsewhere classified
0.698 0.301 0.000
K71 Toxic liver disease
0.698 0.301 0.000
J30-J39 Other diseases of upper respiratory tract
0.698 0.302 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.696 0.304 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.696 0.304 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.695 0.305 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.695 0.305 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.693 0.307 0.000
Y44.2 Anticoagulants
0.692 0.308 0.000
C18.2 Ascending colon
0.692 0.308 0.000
C44.1 Skin of eyelid, including canthus
0.692 0.308 0.000
W25 Contact with sharp glass
0.690 0.310 0.000
Y43 Primarily systemic agents
0.689 0.311 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.688 0.312 0.000
K70.0 Alcoholic fatty liver
0.688 0.312 0.000
Z76 Persons encountering health services in other circumstances
0.688 0.312 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.688 0.312 0.000
C77.1 Intrathoracic lymph nodes
0.688 0.312 0.000
Y40 Systemic antibiotics
0.687 0.312 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.687 0.313 0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.687 0.313 0.000
I81 Portal vein thrombosis
0.686 0.314 0.000
C25.8 Overlapping lesion of pancreas
0.686 0.314 0.000
C25.7 Other parts of pancreas
0.686 0.314 0.000
C25.4 Endocrine pancreas
0.686 0.314 0.000
C25.3 Pancreatic duct
0.686 0.314 0.000
C25.2 Tail of pancreas
0.686 0.314 0.000
C25.1 Body of pancreas
0.686 0.314 0.000
I28 Other diseases of pulmonary vessels
0.685 0.315 0.000
K51.2 Ulcerative (chronic) proctitis
0.685 0.315 0.000
K51.4 Pseudopolyposis of colon
0.685 0.315 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.685 0.315 0.000
I25.6 Silent myocardial ischaemia
0.685 0.315 0.000
I25.4 Coronary artery aneurysm
0.685 0.315 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.685 0.315 0.000
Y42.5 Other oestrogens and progestogens
0.685 0.315 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.684 0.316 0.000
K82.8 Other specified diseases of gallbladder
0.683 0.317 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.683 0.317 0.000
Z12 Special screening examination for neoplasms
0.683 0.317 0.000
E29 Testicular dysfunction
0.683 0.317 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.683 0.317 0.000
S81 Open wound of lower leg
0.682 0.318 0.000
S69 Other and unspecified injuries of wrist and hand
0.681 0.318 0.000
G30-G32 Other degenerative diseases of the nervous system
0.681 0.319 0.000
O00-O08 Pregnancy with abortive outcome
0.680 0.320 0.000
S29 Other and unspecified injuries of thorax
0.679 0.320 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.679 0.320 0.000
S26 Injury of heart
0.679 0.320 0.000
S25 Injury of blood vessels of thorax
0.679 0.320 0.000
S24 Injury of nerves and spinal cord at thorax level
0.679 0.320 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.679 0.320 0.000
S21 Open wound of thorax
0.679 0.320 0.000
D00-D09 In situ neoplasms
0.679 0.321 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.679 0.321 0.000
K76.9 Liver disease, unspecified
0.679 0.321 0.000
S52 Fracture of forearm
0.678 0.322 0.000
E55 Vitamin D deficiency
0.677 0.322 0.000
O47 False labour
0.677 0.323 0.000
I86 Varicose veins of other sites
0.677 0.323 0.000
O48 Prolonged pregnancy
0.677 0.323 0.000
I77.6 Arteritis, unspecified
0.677 0.323 0.000
E86 Volume depletion
0.675 0.325 0.000
S20.2 Contusion of thorax
0.675 0.325 0.000
I80.8 Phlebitis and thrombophlebitis of other sites
0.675 0.325 0.000
Z29 Need for other prophylactic measures
0.675 0.325 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.674 0.326 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.674 0.326 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.673 0.327 0.000
Y84.0 Cardiac catheterisation
0.673 0.327 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.673 0.327 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.673 0.327 0.000
E14 Unspecified diabetes mellitus
0.672 0.328 0.000
H91 Other hearing loss
0.672 0.328 0.000
T66-T78 Other and unspecified effects of external causes
0.671 0.328 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.672 0.328 0.000
Y59 Other and unspecified vaccines and biological substances
0.671 0.329 0.000
Y58 Bacterial vaccines
0.671 0.329 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.671 0.329 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.671 0.329 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.671 0.329 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.671 0.329 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.671 0.329 0.000
Y48 Anaesthetics and therapeutic gases
0.671 0.329 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.671 0.329 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.671 0.329 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.671 0.329 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.671 0.329 0.000
J11 Influenza, virus not identified
0.671 0.329 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.671 0.329 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.669 0.331 0.000
K86.9 Disease of pancreas, unspecified
0.669 0.331 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.668 0.332 0.000
I25.1 Atherosclerotic heart disease
0.668 0.332 0.000
I15 Secondary hypertension
0.667 0.333 0.000
S22.3 Fracture of rib
0.666 0.333 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.666 0.334 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.666 0.334 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.666 0.334 0.000
K50 Crohn's disease [regional enteritis]
0.666 0.334 0.000
G62 Other polyneuropathies
0.665 0.335 0.000
G60 Hereditary and idiopathic neuropathy
0.665 0.335 0.000
O45 Premature separation of placenta [abruptio placentae]
0.665 0.335 0.000
O44 Placenta praevia
0.665 0.335 0.000
O43 Placental disorders
0.665 0.335 0.000
O33 Maternal care for known or suspected disproportion
0.665 0.335 0.000
O31 Complications specific to multiple gestation
0.665 0.335 0.000
O40 Polyhydramnios
0.665 0.335 0.000
J60-J70 Lung diseases due to external agents
0.665 0.335 0.000
Z02 Examination and encounter for administrative purposes
0.664 0.336 0.000
C18.6 Descending colon
0.664 0.336 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.662 0.337 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.662 0.338 0.000
I72 Other aneurysm
0.662 0.338 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.662 0.338 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.662 0.338 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.660 0.340 0.000
I20.8 Other forms of angina pectoris
0.659 0.340 0.000
O80-O84 Delivery
0.659 0.340 0.000
T18.1 Foreign body in oesophagus
0.659 0.341 0.000
X60-X84 Intentional self-harm
0.659 0.341 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.659 0.341 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.658 0.342 0.000
E87.7 Fluid overload
0.658 0.342 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.655 0.344 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.655 0.344 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.655 0.345 0.000
E87.2 Acidosis
0.655 0.345 0.000
C50-C50 Malignant neoplasm of breast
0.654 0.346 0.000
S40 Superficial injury of shoulder and upper arm
0.654 0.346 0.000
S92 Fracture of foot, except ankle
0.653 0.347 0.000
H61 Other disorders of external ear
0.653 0.347 0.000
I88.9 Nonspecific lymphadenitis, unspecified
0.652 0.348 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.652 0.348 0.000
W29 Contact with other powered hand tools and household machinery
0.652 0.348 0.000
K52 Other non-infective gastro-enteritis and colitis
0.651 0.349 0.000
T87 Complications peculiar to reattachment and amputation
0.651 0.349 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.650 0.350 0.000
C18.8 Overlapping lesion of colon
0.650 0.350 0.000
C18.3 Hepatic flexure
0.650 0.350 0.000
C18.1 Appendix
0.650 0.350 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.649 0.351 0.000
E34 Other endocrine disorders
0.649 0.351 0.000
E32 Diseases of thymus
0.649 0.351 0.000
E31 Polyglandular dysfunction
0.649 0.351 0.000
E30 Disorders of puberty, not elsewhere classified
0.649 0.351 0.000
E26 Hyperaldosteronism
0.649 0.351 0.000
E25 Adrenogenital disorders
0.649 0.351 0.000
E20 Hypoparathyroidism
0.649 0.351 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.649 0.351 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.649 0.351 0.000
G90-G99 Other disorders of the nervous system
0.649 0.351 0.000
E22 Hyperfunction of pituitary gland
0.649 0.351 0.000
I05-I09 Chronic rheumatic heart diseases
0.649 0.351 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.648 0.351 0.000
J10 Influenza due to identified influenza virus
0.647 0.353 0.000
V10-V19 Pedal cyclist injured in transport accident
0.647 0.353 0.000
Z74 Problems related to care-provider dependency
0.646 0.354 0.000
Z09.2 Follow-up examination after chemotherapy for other conditions
0.646 0.354 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.644 0.355 0.000
K85.9 Acute pancreatitis, unspecified
0.644 0.356 0.000
S80 Superficial injury of lower leg
0.644 0.356 0.000
J17 Pneumonia in diseases classified elsewhere
0.643 0.357 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.643 0.357 0.000
J12 Viral pneumonia, not elsewhere classified
0.643 0.357 0.000
J09 Influenza due to certain identified influenza virus
0.643 0.357 0.000
K85.1 Biliary acute pancreatitis
0.643 0.357 0.000
E28 Ovarian dysfunction
0.643 0.357 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.643 0.357 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.643 0.357 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.643 0.357 0.000
S82 Fracture of lower leg, including ankle
0.643 0.357 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.642 0.358 0.000
C44.5 Skin of trunk
0.642 0.358 0.000
I12 Hypertensive renal disease
0.642 0.358 0.000
Y54.4 Loop [high-ceiling] diuretics
0.641 0.359 0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus
0.641 0.359 0.000
K86.2 Cyst of pancreas
0.640 0.360 0.000
W44.0 Home
0.640 0.360 0.000
C01 Malignant neoplasm of base of tongue
0.640 0.360 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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