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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75004325
log Bayes Factor = 14.3185
Chromosome 9   position 73,586,372  (GRCh37) Explore rs75004325 on Ensembl!
Variant rs75004325 is part of Cluster X0071

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.997 0.003 0.000
M15-M19 Arthrosis
0.996 0.004 0.000
Chapter XX External causes of morbidity and mortality
0.995 0.005 0.000
M17 Gonarthrosis [arthrosis of knee]
0.995 0.005 0.000
M23 Internal derangement of knee
0.993 0.007 0.000
M17.9 Gonarthrosis, unspecified
0.992 0.008 0.000
M05-M14 Inflammatory polyarthropathies
0.990 0.010 0.000
M25 Other joint disorders, not elsewhere classified
0.989 0.011 0.000
E65-E68 Obesity and other hyperalimentation
0.983 0.017 0.000
Chapter XXI Factors influencing health status and contact with health services
0.982 0.018 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.981 0.019 0.000
Chapter VI Diseases of the nervous system
0.981 0.019 0.000
E66 Obesity
0.972 0.028 0.000
E20-E35 Disorders of other endocrine glands
0.972 0.028 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.970 0.030 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.968 0.032 0.000
Z80 Family history of malignant neoplasm
0.956 0.044 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.956 0.044 0.000
Z92 Personal history of medical treatment
0.954 0.046 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.953 0.047 0.000
Z80.3 Family history of malignant neoplasm of breast
0.951 0.049 0.000
E66.9 Obesity, unspecified
0.946 0.054 0.000
W00-W19 Falls
0.945 0.055 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.941 0.059 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.939 0.061 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.939 0.061 0.000
M25.7 Osteophyte
0.939 0.061 0.000
M23.8 Other internal derangements of knee
0.938 0.062 0.000
Chapter VII Diseases of the eye and adnexa
0.933 0.067 0.000
E10-E14 Diabetes mellitus
0.927 0.073 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.926 0.074 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.926 0.074 0.000
M70-M79 Other soft tissue disorders
0.921 0.079 0.000
D80-D89 Certain disorders involving the immune mechanism
0.921 0.079 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.921 0.079 0.000
Z92.3 Personal history of irradiation
0.920 0.080 0.000
M65-M68 Disorders of synovium and tendon
0.916 0.084 0.000
D60-D64 Aplastic and other anaemias
0.915 0.085 0.000
M17.1 Other primary gonarthrosis
0.914 0.086 0.000
Z01.8 Other specified special examinations
0.912 0.088 0.000
M25.76 Osteophyte (Lower leg)
0.911 0.089 0.000
Chapter X Diseases of the respiratory system
0.910 0.090 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.908 0.092 0.000
M25.8 Other specified joint disorders
0.907 0.093 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.906 0.094 0.000
Chapter XIV Diseases of the genitourinary system
0.903 0.097 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.902 0.098 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.901 0.099 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.901 0.099 0.000
M06 Other rheumatoid arthritis
0.898 0.102 0.000
N20-N23 Urolithiasis
0.898 0.102 0.000
M86-M90 Other osteopathies
0.898 0.102 0.000
N20 Calculus of kidney and ureter
0.897 0.103 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.896 0.104 0.000
J20-J22 Other acute lower respiratory infections
0.895 0.105 0.000
D86 Sarcoidosis
0.892 0.108 0.000
E27 Other disorders of adrenal gland
0.892 0.108 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.887 0.113 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.885 0.115 0.000
J22 Unspecified acute lower respiratory infection
0.885 0.115 0.000
R20 Disturbances of skin sensation
0.884 0.116 0.000
M22 Disorders of patella
0.884 0.116 0.000
M13 Other arthritis
0.877 0.123 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.875 0.125 0.000
G90-G99 Other disorders of the nervous system
0.875 0.125 0.000
M10 Gout
0.873 0.127 0.000
N20.0 Calculus of kidney
0.866 0.134 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.865 0.135 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.864 0.136 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.863 0.137 0.000
J95-J99 Other diseases of the respiratory system
0.862 0.138 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.860 0.140 0.000
M65 Synovitis and tenosynovitis
0.860 0.140 0.000
S40-S49 Injuries to the shoulder and upper arm
0.852 0.148 0.000
N20.1 Calculus of ureter
0.851 0.149 0.000
H43-H45 Disorders of vitreous body and globe
0.850 0.150 0.000
M25.5 Pain in joint
0.849 0.151 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.845 0.155 0.000
N25-N29 Other disorders of kidney and ureter
0.843 0.157 0.000
M21 Other acquired deformities of limbs
0.842 0.157 0.000
Z22 Carrier of infectious disease
0.842 0.158 0.000
R12 Heartburn
0.842 0.158 0.000
E66.8 Other obesity
0.839 0.161 0.000
Y84.8 Other medical procedures
0.838 0.162 0.000
Z96 Presence of other functional implants
0.836 0.164 0.000
W19 Unspecified fall
0.835 0.165 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.835 0.165 0.000
G70-G73 Diseases of myoneural junction and muscle
0.834 0.166 0.000
E11 Non-insulin-dependent diabetes mellitus
0.833 0.167 0.000
Z83 Family history of other specific disorders
0.833 0.167 0.000
M89 Other disorders of bone
0.832 0.168 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.830 0.170 0.000
E00-E07 Disorders of thyroid gland
0.827 0.173 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.826 0.174 0.000
M25.87 Other specified joint disorders (Ankle and foot)
0.825 0.175 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.825 0.175 0.000
T86 Failure and rejection of transplanted organs and tissues
0.824 0.176 0.000
Y43 Primarily systemic agents
0.824 0.176 0.000
T66-T78 Other and unspecified effects of external causes
0.823 0.177 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.823 0.177 0.000
M06.3 Rheumatoid nodule
0.821 0.179 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.820 0.180 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.817 0.183 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.817 0.183 0.000
D86.9 Sarcoidosis, unspecified
0.815 0.185 0.000
M80-M85 Disorders of bone density and structure
0.814 0.186 0.000
R22.1 Localised swelling, mass and lump, neck
0.814 0.186 0.000
Z97 Presence of other devices
0.813 0.187 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.812 0.188 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.812 0.188 0.000
E40-E46 Malnutrition
0.810 0.190 0.000
M22.4 Chondromalacia patellae
0.810 0.190 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.807 0.193 0.000
N20.2 Calculus of kidney with calculus of ureter
0.805 0.195 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.803 0.197 0.000
Z22.3 Carrier of other specified bacterial diseases
0.802 0.198 0.000
M91-M94 Chondropathies
0.802 0.198 0.000
H43 Disorders of vitreous body
0.801 0.199 0.000
Z29 Need for other prophylactic measures
0.800 0.200 0.000
Y44 Agents primarily affecting blood constituents
0.800 0.200 0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.799 0.201 0.000
S90-S99 Injuries to the ankle and foot
0.799 0.201 0.000
R14 Flatulence and related conditions
0.798 0.202 0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.797 0.203 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.795 0.205 0.000
N28.1 Cyst of kidney, acquired
0.794 0.206 0.000
E21.0 Primary hyperparathyroidism
0.793 0.207 0.000
Chapter XXII Codes for special purposes
0.793 0.207 0.000
J98 Other respiratory disorders
0.793 0.207 0.000
Z11.0 Special screening examination for intestinal infectious diseases
0.792 0.208 0.000
S42 Fracture of shoulder and upper arm
0.792 0.208 0.000
Chapter V Mental and behavioural disorders
0.792 0.208 0.000
M13.9 Arthritis, unspecified
0.790 0.210 0.000
M14 Arthropathies in other diseases classified elsewhere
0.790 0.210 0.000
M10.9 Gout, unspecified
0.790 0.210 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.789 0.211 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.788 0.212 0.000
E66.0 Obesity due to excess calories
0.786 0.214 0.000
G81 Hemiplegia
0.785 0.215 0.000
G40-G47 Episodic and paroxysmal disorders
0.785 0.215 0.000
Z98 Other postsurgical states
0.783 0.217 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.783 0.217 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.781 0.219 0.000
W13 Fall from, out of or through building or structure
0.781 0.219 0.000
M89.9 Disorder of bone, unspecified
0.781 0.219 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.781 0.219 0.000
E10 Insulin-dependent diabetes mellitus
0.780 0.220 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.779 0.221 0.000
M25.56 Pain in joint (Lower leg)
0.778 0.222 0.000
Y84.0 Cardiac catheterisation
0.778 0.222 0.000
H25-H28 Disorders of lens
0.776 0.224 0.000
Z89 Acquired absence of limb
0.773 0.227 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.773 0.227 0.000
M07 Psoriatic and enteropathic arthropathies
0.771 0.229 0.000
N00-N08 Glomerular diseases
0.771 0.229 0.000
S80-S89 Injuries to the knee and lower leg
0.769 0.231 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.769 0.231 0.000
M05 Seropositive rheumatoid arthritis
0.769 0.231 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.769 0.231 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.768 0.232 0.000
S60-S69 Injuries to the wrist and hand
0.767 0.233 0.000
M17.0 Primary gonarthrosis, bilateral
0.767 0.233 0.000
M77 Other enthesopathies
0.767 0.233 0.000
M25.9 Joint disorder, unspecified
0.767 0.233 0.000
Z83.4 Family history of other endocrine, nutritional and metabolic diseases
0.766 0.234 0.000
M23.9 Internal derangement of knee, unspecified
0.766 0.234 0.000
H43.1 Vitreous haemorrhage
0.766 0.234 0.000
M25.51 Pain in joint (Shoulder region)
0.764 0.236 0.000
M24 Other specific joint derangements
0.763 0.237 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.763 0.237 0.000
R20.2 Paraesthesia of skin
0.763 0.237 0.000
S42.0 Fracture of clavicle
0.762 0.238 0.000
M30 Polyarteritis nodosa and related conditions
0.759 0.241 0.000
N21 Calculus of lower urinary tract
0.758 0.242 0.000
M15 Polyarthrosis
0.758 0.242 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.756 0.244 0.000
J60-J70 Lung diseases due to external agents
0.755 0.244 0.000
W50-W64 Exposure to animate mechanical forces
0.755 0.245 0.000
G93 Other disorders of brain
0.755 0.245 0.000
E27.8 Other specified disorders of adrenal gland
0.755 0.245 0.000
M31 Other necrotising vasculopathies
0.754 0.246 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.754 0.246 0.000
D55-D59 Haemolytic anaemias
0.753 0.247 0.000
R22.0 Localised swelling, mass and lump, head
0.753 0.247 0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues
0.752 0.247 0.000
M25.72 Osteophyte (Upper arm)
0.751 0.249 0.000
E22 Hyperfunction of pituitary gland
0.751 0.249 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.751 0.249 0.000
S10-S19 Injuries to the neck
0.748 0.252 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.748 0.252 0.000
M23.5 Chronic instability of knee
0.748 0.252 0.000
Z01.9 Special examination, unspecified
0.747 0.253 0.000
Y48 Anaesthetics and therapeutic gases
0.747 0.253 0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)
0.744 0.256 0.000
M23.4 Loose body in knee
0.743 0.257 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.742 0.258 0.000
Z97.4 Presence of external hearing-aid
0.741 0.259 0.000
S42.00 Fracture of clavicle (closed)
0.741 0.259 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.740 0.260 0.000
Y57 Other and unspecified drugs and medicaments
0.740 0.260 0.000
Y84.2 Radiological procedure and radiotherapy
0.739 0.260 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.738 0.261 0.000
G62 Other polyneuropathies
0.738 0.262 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.737 0.263 0.000
D86.3 Sarcoidosis of skin
0.737 0.263 0.000
M25.84 Other specified joint disorders (Hand)
0.737 0.263 0.000
E20 Hypoparathyroidism
0.736 0.263 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.736 0.264 0.000
R22.3 Localised swelling, mass and lump, upper limb
0.736 0.264 0.000
Z96.1 Presence of intraocular lens
0.736 0.264 0.000
Z92.0 Personal history of contraception
0.735 0.265 0.000
T86.1 Kidney transplant failure and rejection
0.735 0.265 0.000
J00-J06 Acute upper respiratory infections
0.735 0.265 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.734 0.266 0.000
V80-V89 Other land transport accidents
0.734 0.266 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.734 0.266 0.000
D62 Acute posthaemorrhagic anaemia
0.734 0.266 0.000
S20-S29 Injuries to the thorax
0.734 0.266 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.733 0.267 0.000
G60 Hereditary and idiopathic neuropathy
0.732 0.267 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.732 0.268 0.000
H53-H54 Visual disturbances and blindness
0.732 0.268 0.000
Z80.8 Family history of malignant neoplasm of other organs or systems
0.732 0.268 0.000
D63.0 Anaemia in neoplastic disease
0.732 0.268 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.732 0.268 0.000
M25.3 Other instability of joint
0.731 0.268 0.000
E34 Other endocrine disorders
0.731 0.269 0.000
X20-X29 Contact with venomous animals and plants
0.730 0.270 0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.729 0.271 0.000
G30-G32 Other degenerative diseases of the nervous system
0.729 0.271 0.000
V40-V49 Car occupant injured in transport accident
0.728 0.272 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.728 0.272 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.727 0.273 0.000
E11.5 With peripheral circulatory complications
0.727 0.273 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.724 0.276 0.000
E50-E64 Other nutritional deficiencies
0.724 0.276 0.000
W17 Other fall from one level to another
0.724 0.276 0.000
Z98.0 Intestinal bypass and anastomosis status
0.723 0.277 0.000
M06.34 Rheumatoid nodule (Hand)
0.722 0.278 0.000
M60-M63 Disorders of muscles
0.721 0.279 0.000
G70 Myasthenia gravis and other myoneural disorders
0.721 0.279 0.000
Y43.3 Other antineoplastic drugs
0.720 0.280 0.000
G80 Infantile cerebral palsy
0.719 0.281 0.000
T85.2 Mechanical complication of intraocular lens
0.719 0.281 0.000
Z11.2 Special screening examination for other bacterial diseases
0.719 0.281 0.000
E70-E90 Metabolic disorders
0.719 0.281 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.719 0.281 0.000
H25 Senile cataract
0.719 0.281 0.000
Z01.5 Diagnostic skin and sensitisation tests
0.718 0.282 0.000
H25.1 Senile nuclear cataract
0.718 0.282 0.000
D64 Other anaemias
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
M34 Systemic sclerosis
0.717 0.283 0.000
M33 Dermatopolymyositis
0.717 0.283 0.000
M32 Systemic lupus erythematosus
0.717 0.283 0.000
Z01.6 Radiological examination, not elsewhere classified
0.716 0.284 0.000
M21.1 Varus deformity, not elsewhere classified
0.716 0.284 0.000
M10.99 Gout, unspecified (Site unspecified)
0.716 0.284 0.000
R19.4 Change in bowel habit
0.716 0.284 0.000
T33-T35 Frostbite
0.715 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.285 0.000
T00-T07 Injuries involving multiple body regions
0.715 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.714 0.286 0.000
Y10-Y34 Event of undetermined intent
0.714 0.286 0.000
Y00-Y09 Assault
0.714 0.286 0.000
X85-X99 Assault
0.714 0.286 0.000
X30-X39 Exposure to forces of nature
0.714 0.286 0.000
X10-X19 Contact with heat and hot substances
0.714 0.286 0.000
X00-X09 Exposure to smoke, fire and flames
0.714 0.286 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.714 0.286 0.000
W75-W84 Other accidental threats to breathing
0.714 0.286 0.000
W65-W74 Accidental drowning and submersion
0.714 0.286 0.000
V98-V99 Other and unspecified transport accidents
0.714 0.286 0.000
V95-V97 Air and space transport accidents
0.714 0.286 0.000
V90-V94 Water transport accidents
0.714 0.286 0.000
V70-V79 Bus occupant injured in transport accident
0.714 0.286 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.714 0.286 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.714 0.286 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.714 0.286 0.000
V01-V09 Pedestrian injured in transport accident
0.714 0.286 0.000
M17.5 Other secondary gonarthrosis
0.713 0.287 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.713 0.287 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.713 0.287 0.000
M17.3 Other posttraumatic gonarthrosis
0.712 0.288 0.000
D86.1 Sarcoidosis of lymph nodes
0.712 0.288 0.000
M23.1 Discoid meniscus (congenital)
0.712 0.288 0.000
M23.0 Cystic meniscus
0.712 0.288 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.712 0.288 0.000
E11.3 With ophthalmic complications
0.712 0.288 0.000
X50-X57 Overexertion, travel and privation
0.711 0.288 0.000
M18 Arthrosis of first carpometacarpal joint
0.711 0.289 0.000
Y76 Obstetric and gynaecological devices associated with adverse incidents
0.711 0.289 0.000
Z81 Family history of mental and behavioural disorders
0.710 0.290 0.000
M12 Other specific arthropathies
0.709 0.290 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.709 0.290 0.000
M08 Juvenile arthritis
0.709 0.290 0.000
M25.2 Flail joint
0.709 0.291 0.000
M25.1 Fistula of joint
0.709 0.291 0.000
G82 Paraplegia and tetraplegia
0.709 0.291 0.000
R22.2 Localised swelling, mass and lump, trunk
0.708 0.292 0.000
Z29.2 Other prophylactic chemotherapy
0.708 0.292 0.000
Z96.6 Presence of orthopaedic joint implants
0.707 0.293 0.000
Y84.1 Kidney dialysis
0.707 0.293 0.000
V10-V19 Pedal cyclist injured in transport accident
0.706 0.294 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.705 0.295 0.000
E67 Other hyperalimentation
0.705 0.295 0.000
E68 Sequelae of hyperalimentation
0.705 0.295 0.000
E65 Localised adiposity
0.705 0.295 0.000
M87 Osteonecrosis
0.705 0.295 0.000
M25.81 Other specified joint disorders (Shoulder region)
0.704 0.296 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.704 0.296 0.000
W19.3 Sports and athletics area
0.704 0.296 0.000
Z96.7 Presence of other bone and tendon implants
0.704 0.296 0.000
T87 Complications peculiar to reattachment and amputation
0.703 0.296 0.000
G83 Other paralytic syndromes
0.703 0.297 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.703 0.297 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.703 0.297 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.703 0.297 0.000
H55-H59 Other disorders of eye and adnexa
0.702 0.297 0.000
M25.0 Haemarthrosis
0.702 0.298 0.000
M79.1 Myalgia
0.702 0.298 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.701 0.299 0.000
D80 Immunodeficiency with predominantly antibody defects
0.701 0.299 0.000
X60-X84 Intentional self-harm
0.700 0.299 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.700 0.300 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.700 0.300 0.000
M65.3 Trigger finger
0.700 0.300 0.000
W06 Fall involving bed
0.700 0.300 0.000
Y44.2 Anticoagulants
0.700 0.300 0.000
M00-M03 Infectious arthropathies
0.699 0.301 0.000
M25.71 Osteophyte (Shoulder region)
0.699 0.301 0.000
T78 Adverse effects, not elsewhere classified
0.699 0.301 0.000
G81.9 Hemiplegia, unspecified
0.698 0.302 0.000
M71 Other bursopathies
0.697 0.303 0.000
D86.8 Sarcoidosis of other and combined sites
0.697 0.303 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.697 0.303 0.000
E66.1 Drug-induced obesity
0.697 0.303 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.697 0.303 0.000
E32 Diseases of thymus
0.697 0.303 0.000
E31 Polyglandular dysfunction
0.697 0.303 0.000
E30 Disorders of puberty, not elsewhere classified
0.697 0.303 0.000
E26 Hyperaldosteronism
0.697 0.303 0.000
E25 Adrenogenital disorders
0.697 0.303 0.000
E24 Cushing's syndrome
0.697 0.303 0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
0.695 0.305 0.000
W10 Fall on and from stairs and steps
0.695 0.305 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.695 0.305 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.695 0.305 0.000
E13 Other specified diabetes mellitus
0.694 0.306 0.000
Z84 Family history of other conditions
0.694 0.306 0.000
E23 Hypofunction and other disorders of pituitary gland
0.693 0.306 0.000
E10.5 With peripheral circulatory complications
0.693 0.307 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.693 0.307 0.000
J69 Pneumonitis due to solids and liquids
0.693 0.307 0.000
R18 Ascites
0.692 0.308 0.000
D86.0 Sarcoidosis of lung
0.692 0.308 0.000
S81 Open wound of lower leg
0.691 0.309 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.691 0.309 0.000
M72 Fibroblastic disorders
0.690 0.310 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.690 0.310 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.689 0.311 0.000
G91 Hydrocephalus
0.689 0.311 0.000
M23.3 Other meniscus derangements
0.689 0.311 0.000
W19.4 Street and highway
0.689 0.311 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.687 0.313 0.000
Z80.6 Family history of leukaemia
0.685 0.315 0.000
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs
0.685 0.315 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.685 0.315 0.000
T82.1 Mechanical complication of cardiac electronic device
0.685 0.315 0.000
Z92.9 Personal history of medical treatment, unspecified
0.684 0.316 0.000
Z92.8 Personal history of other medical treatment
0.684 0.316 0.000
Z92.5 Personal history of rehabilitation measures
0.684 0.316 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.684 0.316 0.000
E10.4 With neurological complications
0.683 0.317 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.683 0.317 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.683 0.317 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.683 0.317 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.683 0.317 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.683 0.317 0.000
S70-S79 Injuries to the hip and thigh
0.683 0.317 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.682 0.318 0.000
H49 Paralytic strabismus
0.682 0.318 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.682 0.318 0.000
E07 Other disorders of thyroid
0.681 0.319 0.000
M85 Other disorders of bone density and structure
0.681 0.319 0.000
M25.58 Pain in joint (Other)
0.681 0.319 0.000
R22.9 Localised swelling, mass and lump, unspecified
0.680 0.319 0.000
M06.0 Seronegative rheumatoid arthritis
0.680 0.320 0.000
M11 Other crystal arthropathies
0.680 0.320 0.000
M06.4 Inflammatory polyarthropathy
0.680 0.320 0.000
E89.0 Postprocedural hypothyroidism
0.680 0.320 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.680 0.320 0.000
M35 Other systemic involvement of connective tissue
0.679 0.321 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.678 0.322 0.000
W15 Fall from cliff
0.678 0.322 0.000
W14 Fall from tree
0.678 0.322 0.000
W12 Fall on and from scaffolding
0.678 0.322 0.000
W11 Fall on and from ladder
0.678 0.322 0.000
W09 Fall involving playground equipment
0.678 0.322 0.000
W05 Fall involving wheelchair
0.678 0.322 0.000
W04 Fall while being carried or supported by other persons
0.678 0.322 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.678 0.322 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.678 0.322 0.000
W00 Fall on same level involving ice and snow
0.678 0.322 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.677 0.322 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.677 0.323 0.000
H21 Other disorders of iris and ciliary body
0.677 0.323 0.000
Q60-Q64 Congenital malformations of the urinary system
0.677 0.323 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.676 0.324 0.000
H18 Other disorders of cornea
0.675 0.325 0.000
E46 Unspecified protein-energy malnutrition
0.674 0.325 0.000
E29 Testicular dysfunction
0.674 0.326 0.000
D61 Other aplastic anaemias
0.674 0.326 0.000
Y59 Other and unspecified vaccines and biological substances
0.673 0.326 0.000
Y58 Bacterial vaccines
0.673 0.326 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.673 0.326 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.673 0.326 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.673 0.326 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.673 0.326 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.673 0.326 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.673 0.326 0.000
M25.79 Osteophyte (Site unspecified)
0.673 0.327 0.000
M25.73 Osteophyte (Forearm)
0.673 0.327 0.000
M25.70 Osteophyte (Multiple sites)
0.673 0.327 0.000
M50-M54 Other dorsopathies
0.673 0.327 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.672 0.327 0.000
M23.87 Other internal derangements of knee (Capsular ligament)
0.672 0.328 0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)
0.672 0.328 0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)
0.672 0.328 0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.672 0.328 0.000
M23.80 Other internal derangements of knee (Multiple sites)
0.672 0.328 0.000
M25.54 Pain in joint (Hand)
0.672 0.328 0.000
M76 Enthesopathies of lower limb, excluding foot
0.671 0.328 0.000
E06 Thyroiditis
0.671 0.329 0.000
M79.8 Other specified soft tissue disorders
0.671 0.329 0.000
Z91.8 Personal history of other specified risk-factors, not elsewhere classified
0.671 0.329 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.671 0.329 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.670 0.330 0.000
R16.0 Hepatomegaly, not elsewhere classified
0.669 0.331 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.669 0.331 0.000
W18 Other fall on same level
0.668 0.331 0.000
T25 Burn and corrosion of ankle and foot
0.668 0.332 0.000
M94 Other disorders of cartilage
0.666 0.334 0.000
E12 Malnutrition-related diabetes mellitus
0.665 0.335 0.000
Z10 Routine general health check-up of defined subpopulation
0.664 0.336 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.664 0.336 0.000
Y40 Systemic antibiotics
0.664 0.336 0.000
Z28 Immunisation not carried out
0.664 0.336 0.000
Z27 Need for immunisation against combinations of infectious diseases
0.664 0.336 0.000
Z26 Need for immunisation against other single infectious diseases
0.664 0.336 0.000
Z25 Need for immunisation against other single viral diseases
0.664 0.336 0.000
Z24 Need for immunisation against certain single viral diseases
0.664 0.336 0.000
Z23 Need for immunisation against single bacterial diseases
0.664 0.336 0.000
Z20 Contact with and exposure to communicable diseases
0.664 0.336 0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status
0.664 0.336 0.000
W08 Fall involving other furniture
0.663 0.336 0.000
W13.9 Unspecified place
0.663 0.336 0.000
M77.1 Lateral epicondylitis
0.663 0.337 0.000
E27.9 Disorder of adrenal gland, unspecified
0.663 0.337 0.000
M84 Disorders of continuity of bone
0.663 0.337 0.000
Z86 Personal history of certain other diseases
0.663 0.337 0.000
Z91.5 Personal history of self-harm
0.662 0.338 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.662 0.338 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.660 0.339 0.000
D84 Other immunodeficiencies
0.660 0.340 0.000
D83 Common variable immunodeficiency
0.660 0.340 0.000
D82 Immunodeficiency associated with other major defects
0.660 0.340 0.000
D81 Combined immunodeficiencies
0.660 0.340 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.660 0.340 0.000
Z01.7 Laboratory examination
0.660 0.340 0.000
Z01.3 Examination of blood pressure
0.660 0.340 0.000
Z01.2 Dental examination
0.660 0.340 0.000
Z01.1 Examination of ears and hearing
0.660 0.340 0.000
Z01.0 Examination of eyes and vision
0.660 0.340 0.000
G61 Inflammatory polyneuropathy
0.659 0.340 0.000
N99-N99 Other disorders of the genitourinary system
0.659 0.341 0.000
N21.0 Calculus in bladder
0.658 0.342 0.000
W07 Fall involving chair
0.658 0.342 0.000
T63 Toxic effect of contact with venomous animals
0.657 0.343 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.657 0.343 0.000
M66 Spontaneous rupture of synovium and tendon
0.657 0.343 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.656 0.344 0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)
0.656 0.344 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.656 0.344 0.000
M40-M43 Deforming dorsopathies
0.656 0.344 0.000
G90 Disorders of autonomic nervous system
0.654 0.346 0.000
Y79 Orthopaedic devices associated with adverse incidents
0.652 0.348 0.000
N20.9 Urinary calculus, unspecified
0.652 0.348 0.000
M79.0 Rheumatism, unspecified
0.652 0.348 0.000
T79-T79 Certain early complications of trauma
0.652 0.348 0.000
E27.1 Primary adrenocortical insufficiency
0.651 0.349 0.000
Y84.9 Medical procedure, unspecified
0.651 0.349 0.000
Y84.7 Blood-sampling
0.651 0.349 0.000
Y84.5 Insertion of gastric or duodenal sound
0.651 0.349 0.000
Y84.4 Aspiration of fluid
0.651 0.349 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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