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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75005694
log Bayes Factor = 15.5513
Chromosome 16   position 28,320,382  (GRCh37) Explore rs75005694 on Ensembl!
Variant rs75005694 is part of Cluster X0070

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
0.997 0.003 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.997 0.003 0.000
R50-R69 General symptoms and signs
0.995 0.005 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.994 0.006 0.000
E70-E90 Metabolic disorders
0.992 0.008 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.992 0.008 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.987 0.013 0.000
M70-M79 Other soft tissue disorders
0.984 0.016 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.983 0.017 0.000
M10 Gout
0.983 0.017 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.983 0.017 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.983 0.017 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.976 0.024 0.000
M10.9 Gout, unspecified
0.971 0.029 0.000
M06 Other rheumatoid arthritis
0.962 0.038 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.962 0.038 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.960 0.040 0.000
L03 Cellulitis
0.959 0.041 0.000
E87.5 Hyperkalaemia
0.958 0.042 0.000
M10.99 Gout, unspecified (Site unspecified)
0.956 0.044 0.000
K20 Oesophagitis
0.955 0.045 0.000
M79.8 Other specified soft tissue disorders
0.955 0.045 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.955 0.045 0.000
K80 Cholelithiasis
0.953 0.047 0.000
M20-M25 Other joint disorders
0.952 0.048 0.000
K65-K67 Diseases of peritoneum
0.950 0.050 0.000
M13 Other arthritis
0.945 0.055 0.000
K83 Other diseases of biliary tract
0.938 0.062 0.000
L03.1 Cellulitis of other parts of limb
0.937 0.063 0.000
B95-B98 Bacterial, viral and other infectious agents
0.934 0.066 0.000
S60-S69 Injuries to the wrist and hand
0.934 0.066 0.000
E87.7 Fluid overload
0.932 0.068 0.000
M06.9 Rheumatoid arthritis, unspecified
0.929 0.071 0.000
B35-B49 Mycoses
0.929 0.071 0.000
E86 Volume depletion
0.926 0.074 0.000
K29 Gastritis and duodenitis
0.925 0.075 0.000
R63 Symptoms and signs concerning food and fluid intake
0.924 0.076 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.920 0.080 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.908 0.092 0.000
M13.9 Arthritis, unspecified
0.903 0.097 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.896 0.104 0.000
K83.8 Other specified diseases of biliary tract
0.896 0.104 0.000
R53 Malaise and fatigue
0.895 0.105 0.000
K66 Other disorders of peritoneum
0.893 0.107 0.000
A30-A49 Other bacterial diseases
0.882 0.117 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.881 0.119 0.000
B37 Candidiasis
0.880 0.120 0.000
M25 Other joint disorders, not elsewhere classified
0.879 0.121 0.000
Chapter II Neoplasms
0.877 0.123 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.876 0.124 0.000
R51 Headache
0.874 0.126 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.873 0.127 0.000
M23 Internal derangement of knee
0.871 0.129 0.000
D80-D89 Certain disorders involving the immune mechanism
0.868 0.132 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.867 0.133 0.000
K85 Acute pancreatitis
0.866 0.134 0.000
R63.4 Abnormal weight loss
0.865 0.135 0.000
K86 Other diseases of pancreas
0.865 0.135 0.000
Chapter XX External causes of morbidity and mortality
0.861 0.139 0.000
B25-B34 Other viral diseases
0.860 0.140 0.000
R52 Pain, not elsewhere classified
0.859 0.141 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.859 0.141 0.000
K29.8 Duodenitis
0.856 0.144 0.000
R47-R49 Symptoms and signs involving speech and voice
0.855 0.145 0.000
S80-S89 Injuries to the knee and lower leg
0.855 0.145 0.000
E83 Disorders of mineral metabolism
0.851 0.149 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.850 0.150 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.850 0.150 0.000
Chapter XXII Codes for special purposes
0.849 0.151 0.000
K29.5 Chronic gastritis, unspecified
0.848 0.152 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.842 0.158 0.000
L05 Pilonidal cyst
0.841 0.159 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.839 0.161 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.834 0.165 0.000
E50-E64 Other nutritional deficiencies
0.834 0.166 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.832 0.168 0.000
M79.6 Pain in limb
0.824 0.175 0.000
K66.0 Peritoneal adhesions
0.824 0.176 0.000
E87.2 Acidosis
0.823 0.177 0.000
M65-M68 Disorders of synovium and tendon
0.821 0.179 0.000
R26 Abnormalities of gait and mobility
0.820 0.180 0.000
D70 Agranulocytosis
0.817 0.183 0.000
M91-M94 Chondropathies
0.813 0.187 0.000
B37.8 Candidiasis of other sites
0.811 0.189 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.809 0.191 0.000
R59 Enlarged lymph nodes
0.808 0.192 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.808 0.192 0.000
K35-K38 Diseases of appendix
0.807 0.193 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.806 0.194 0.000
L20-L30 Dermatitis and eczema
0.805 0.195 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.803 0.197 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.802 0.198 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.802 0.198 0.000
B99-B99 Other infectious diseases
0.799 0.201 0.000
Chapter X Diseases of the respiratory system
0.799 0.201 0.000
M21 Other acquired deformities of limbs
0.799 0.201 0.000
M07 Psoriatic and enteropathic arthropathies
0.799 0.201 0.000
C51-C58 Malignant neoplasms of female genital organs
0.798 0.202 0.000
R40 Somnolence, stupor and coma
0.797 0.203 0.000
K80.1 Calculus of gallbladder with other cholecystitis
0.796 0.204 0.000
M25.5 Pain in joint
0.793 0.207 0.000
R60 Oedema, not elsewhere classified
0.793 0.207 0.000
D60-D64 Aplastic and other anaemias
0.792 0.208 0.000
M23.8 Other internal derangements of knee
0.791 0.209 0.000
R14 Flatulence and related conditions
0.790 0.210 0.000
L50-L54 Urticaria and erythema
0.787 0.213 0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.787 0.213 0.000
L03.8 Cellulitis of other sites
0.786 0.214 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.786 0.214 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.786 0.214 0.000
L40-L45 Papulosquamous disorders
0.781 0.219 0.000
J95-J99 Other diseases of the respiratory system
0.781 0.219 0.000
R49 Voice disturbances
0.780 0.220 0.000
K65 Peritonitis
0.778 0.222 0.000
R45 Symptoms and signs involving emotional state
0.777 0.223 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.777 0.223 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.777 0.223 0.000
S00-S09 Injuries to the head
0.777 0.223 0.000
M79.7 Fibromyalgia
0.777 0.223 0.000
D86 Sarcoidosis
0.776 0.223 0.000
M77 Other enthesopathies
0.776 0.224 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.775 0.225 0.000
K85.9 Acute pancreatitis, unspecified
0.772 0.228 0.000
K82 Other diseases of gallbladder
0.772 0.228 0.000
C64-C68 Malignant neoplasms of urinary tract
0.772 0.228 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.772 0.228 0.000
S82 Fracture of lower leg, including ankle
0.772 0.228 0.000
S61 Open wound of wrist and hand
0.771 0.229 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.770 0.230 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.768 0.232 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.766 0.234 0.000
M72 Fibroblastic disorders
0.766 0.234 0.000
M45-M49 Spondylopathies
0.766 0.234 0.000
K29.2 Alcoholic gastritis
0.765 0.235 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.764 0.236 0.000
E87.6 Hypokalaemia
0.764 0.236 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.764 0.236 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.763 0.237 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.763 0.237 0.000
M86-M90 Other osteopathies
0.763 0.237 0.000
R50 Fever of unknown origin
0.763 0.237 0.000
K70-K77 Diseases of liver
0.762 0.238 0.000
B34 Viral infection of unspecified site
0.762 0.238 0.000
J98 Other respiratory disorders
0.760 0.240 0.000
L03.9 Cellulitis, unspecified
0.759 0.241 0.000
R56 Convulsions, not elsewhere classified
0.758 0.242 0.000
R41.0 Disorientation, unspecified
0.758 0.242 0.000
R11 Nausea and vomiting
0.758 0.242 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.757 0.243 0.000
A41 Other septicaemia
0.756 0.244 0.000
E65-E68 Obesity and other hyperalimentation
0.755 0.245 0.000
R61 Hyperhidrosis
0.755 0.245 0.000
C50-C50 Malignant neoplasm of breast
0.754 0.246 0.000
M05 Seropositive rheumatoid arthritis
0.753 0.247 0.000
S70-S79 Injuries to the hip and thigh
0.753 0.247 0.000
K27 Peptic ulcer, site unspecified
0.753 0.247 0.000
M11 Other crystal arthropathies
0.752 0.248 0.000
R57 Shock, not elsewhere classified
0.749 0.251 0.000
Chapter V Mental and behavioural disorders
0.749 0.251 0.000
S62 Fracture at wrist and hand level
0.748 0.252 0.000
M79.1 Myalgia
0.747 0.253 0.000
J98.1 Pulmonary collapse
0.747 0.253 0.000
S68 Traumatic amputation of wrist and hand
0.747 0.253 0.000
R63.0 Anorexia
0.746 0.254 0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
0.745 0.255 0.000
K66.8 Other specified disorders of peritoneum
0.745 0.255 0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
0.743 0.257 0.000
E83.4 Disorders of magnesium metabolism
0.743 0.257 0.000
L05.9 Pilonidal cyst without abscess
0.740 0.260 0.000
A00-A09 Intestinal infectious diseases
0.739 0.261 0.000
M00-M03 Infectious arthropathies
0.738 0.261 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.738 0.262 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.738 0.262 0.000
M06.0 Seronegative rheumatoid arthritis
0.738 0.262 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.738 0.262 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.737 0.263 0.000
Chapter VIII Diseases of the ear and mastoid process
0.737 0.263 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.737 0.263 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.735 0.264 0.000
M95.0 Acquired deformity of nose
0.735 0.265 0.000
M79.5 Residual foreign body in soft tissue
0.734 0.266 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.732 0.268 0.000
B37.3 Candidiasis of vulva and vagina
0.731 0.269 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.730 0.270 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.730 0.270 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.729 0.271 0.000
K29.1 Other acute gastritis
0.727 0.273 0.000
R49.0 Dysphonia
0.726 0.274 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.726 0.274 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.725 0.275 0.000
M10.96 Gout, unspecified (Lower leg)
0.724 0.276 0.000
S10-S19 Injuries to the neck
0.724 0.276 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.724 0.276 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.724 0.276 0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.723 0.277 0.000
A49 Bacterial infection of unspecified site
0.720 0.280 0.000
E20-E35 Disorders of other endocrine glands
0.720 0.280 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.720 0.280 0.000
D86.9 Sarcoidosis, unspecified
0.717 0.283 0.000
M80-M85 Disorders of bone density and structure
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M22 Disorders of patella
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
M14 Arthropathies in other diseases classified elsewhere
0.717 0.283 0.000
M12 Other specific arthropathies
0.717 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.717 0.283 0.000
M08 Juvenile arthritis
0.717 0.283 0.000
D62 Acute posthaemorrhagic anaemia
0.716 0.284 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.715 0.285 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.715 0.285 0.000
B65-B83 Helminthiases
0.715 0.285 0.000
B50-B64 Protozoal diseases
0.715 0.285 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.715 0.285 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.715 0.285 0.000
A80-A89 Viral infections of the central nervous system
0.715 0.285 0.000
A75-A79 Rickettsioses
0.715 0.285 0.000
A70-A74 Other diseases caused by chlamydiae
0.715 0.285 0.000
A65-A69 Other spirochaetal diseases
0.715 0.285 0.000
A20-A28 Certain zoonotic bacterial diseases
0.715 0.285 0.000
A15-A19 Tuberculosis
0.715 0.285 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.715 0.285 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.713 0.287 0.000
R62 Lack of expected normal physiological development
0.713 0.287 0.000
R64 Cachexia
0.713 0.287 0.000
R58 Haemorrhage, not elsewhere classified
0.713 0.287 0.000
E40-E46 Malnutrition
0.712 0.287 0.000
K90-K93 Other diseases of the digestive system
0.712 0.288 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.712 0.288 0.000
E85 Amyloidosis
0.711 0.289 0.000
E84 Cystic fibrosis
0.711 0.289 0.000
E79 Disorders of purine and pyrimidine metabolism
0.711 0.289 0.000
E77 Disorders of glycoprotein metabolism
0.711 0.289 0.000
E76 Disorders of glycosaminoglycan metabolism
0.711 0.289 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.711 0.289 0.000
E74 Other disorders of carbohydrate metabolism
0.711 0.289 0.000
E73 Lactose intolerance
0.711 0.289 0.000
E72 Other disorders of amino-acid metabolism
0.711 0.289 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.711 0.289 0.000
E70 Disorders of aromatic amino-acid metabolism
0.711 0.289 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.711 0.289 0.000
R54 Senility
0.711 0.289 0.000
L10-L14 Bullous disorders
0.711 0.289 0.000
R60.9 Oedema, unspecified
0.709 0.290 0.000
E83.1 Disorders of iron metabolism
0.709 0.291 0.000
K86.1 Other chronic pancreatitis
0.709 0.291 0.000
L08 Other local infections of skin and subcutaneous tissue
0.709 0.291 0.000
K21 Gastro-oesophageal reflux disease
0.709 0.291 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.707 0.293 0.000
E87.4 Mixed disorder of acid-base balance
0.707 0.293 0.000
E87.3 Alkalosis
0.707 0.293 0.000
D00-D09 In situ neoplasms
0.707 0.293 0.000
M79.67 Pain in limb (Ankle and foot)
0.707 0.293 0.000
S90-S99 Injuries to the ankle and foot
0.707 0.293 0.000
R52.0 Acute pain
0.707 0.293 0.000
M76 Enthesopathies of lower limb, excluding foot
0.705 0.294 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.705 0.294 0.000
M71 Other bursopathies
0.705 0.294 0.000
K28 Gastrojejunal ulcer
0.705 0.295 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.705 0.295 0.000
M10.4 Other secondary gout
0.705 0.295 0.000
M10.3 Gout due to impairment of renal function
0.705 0.295 0.000
M10.2 Drug-induced gout
0.705 0.295 0.000
M10.1 Lead-induced gout
0.705 0.295 0.000
M10.0 Idiopathic gout
0.705 0.295 0.000
T79-T79 Certain early complications of trauma
0.705 0.295 0.000
T33-T35 Frostbite
0.705 0.295 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.705 0.295 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.705 0.295 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.705 0.295 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.705 0.295 0.000
T00-T07 Injuries involving multiple body regions
0.705 0.295 0.000
L04 Acute lymphadenitis
0.705 0.295 0.000
L01 Impetigo
0.705 0.295 0.000
L00 Staphylococcal scalded skin syndrome
0.705 0.295 0.000
M23.0 Cystic meniscus
0.705 0.295 0.000
M79.0 Rheumatism, unspecified
0.704 0.296 0.000
R68 Other general symptoms and signs
0.704 0.296 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.703 0.297 0.000
M25.4 Effusion of joint
0.702 0.297 0.000
K81 Cholecystitis
0.702 0.298 0.000
K26 Duodenal ulcer
0.702 0.298 0.000
R41.3 Other amnesia
0.702 0.298 0.000
S60 Superficial injury of wrist and hand
0.701 0.299 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.700 0.300 0.000
M79.9 Soft tissue disorder, unspecified
0.700 0.300 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.700 0.300 0.000
M79.3 Panniculitis, unspecified
0.700 0.300 0.000
M79.2 Neuralgia and neuritis, unspecified
0.700 0.300 0.000
E88 Other metabolic disorders
0.699 0.300 0.000
D80 Immunodeficiency with predominantly antibody defects
0.699 0.301 0.000
R59.1 Generalised enlarged lymph nodes
0.699 0.301 0.000
S69 Other and unspecified injuries of wrist and hand
0.697 0.303 0.000
M10.98 Gout, unspecified (Other)
0.696 0.303 0.000
M10.95 Gout, unspecified (Pelvic region and thigh)
0.696 0.303 0.000
M10.94 Gout, unspecified (Hand)
0.696 0.303 0.000
M10.93 Gout, unspecified (Forearm)
0.696 0.303 0.000
M10.92 Gout, unspecified (Upper arm)
0.696 0.303 0.000
M10.91 Gout, unspecified (Shoulder region)
0.696 0.303 0.000
M10.90 Gout, unspecified (Multiple sites)
0.696 0.303 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.696 0.304 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.696 0.304 0.000
M13.0 Polyarthritis, unspecified
0.696 0.304 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.696 0.304 0.000
K83.0 Cholangitis
0.694 0.306 0.000
B37.0 Candidal stomatitis
0.694 0.306 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.693 0.307 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.693 0.307 0.000
K22 Other diseases of oesophagus
0.692 0.308 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.692 0.308 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.692 0.308 0.000
T66-T78 Other and unspecified effects of external causes
0.691 0.308 0.000
O42 Premature rupture of membranes
0.691 0.309 0.000
B34.9 Viral infection, unspecified
0.691 0.309 0.000
S64 Injury of nerves at wrist and hand level
0.691 0.309 0.000
S67 Crushing injury of wrist and hand
0.690 0.310 0.000
B15-B19 Viral hepatitis
0.690 0.310 0.000
M06.8 Other specified rheumatoid arthritis
0.690 0.310 0.000
M06.4 Inflammatory polyarthropathy
0.690 0.310 0.000
M06.3 Rheumatoid nodule
0.690 0.310 0.000
M06.2 Rheumatoid bursitis
0.690 0.310 0.000
M06.1 Adult-onset Still's disease
0.690 0.310 0.000
D55-D59 Haemolytic anaemias
0.690 0.310 0.000
M21.3 Wrist or foot drop (acquired)
0.689 0.311 0.000
M13.98 Arthritis, unspecified (Other)
0.689 0.311 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.688 0.311 0.000
R52.1 Chronic intractable pain
0.688 0.311 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.688 0.311 0.000
E53 Deficiency of other B group vitamins
0.688 0.312 0.000
E87.0 Hyperosmolality and hypernatraemia
0.685 0.314 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.686 0.314 0.000
M79.88 Other specified soft tissue disorders (Other)
0.684 0.315 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.684 0.315 0.000
M79.83 Other specified soft tissue disorders (Forearm)
0.684 0.315 0.000
M79.82 Other specified soft tissue disorders (Upper arm)
0.684 0.315 0.000
M79.81 Other specified soft tissue disorders (Shoulder region)
0.684 0.315 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.684 0.315 0.000
R46 Symptoms and signs involving appearance and behaviour
0.684 0.316 0.000
R43 Disturbances of smell and taste
0.684 0.316 0.000
K80.3 Calculus of bile duct with cholangitis
0.683 0.317 0.000
K80.8 Other cholelithiasis
0.683 0.317 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.683 0.317 0.000
M34 Systemic sclerosis
0.683 0.317 0.000
M33 Dermatopolymyositis
0.683 0.317 0.000
M32 Systemic lupus erythematosus
0.683 0.317 0.000
M30 Polyarteritis nodosa and related conditions
0.683 0.317 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.682 0.318 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.682 0.318 0.000
R18 Ascites
0.682 0.318 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.681 0.319 0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere
0.681 0.319 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.680 0.320 0.000
M40-M43 Deforming dorsopathies
0.680 0.320 0.000
K80.4 Calculus of bile duct with cholecystitis
0.679 0.321 0.000
K31 Other diseases of stomach and duodenum
0.678 0.322 0.000
M13.8 Other specified arthritis
0.677 0.323 0.000
M13.1 Monoarthritis, not elsewhere classified
0.677 0.323 0.000
S40-S49 Injuries to the shoulder and upper arm
0.677 0.323 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.675 0.325 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.674 0.326 0.000
R26.3 Immobility
0.674 0.326 0.000
K83.9 Disease of biliary tract, unspecified
0.673 0.327 0.000
K83.5 Biliary cyst
0.673 0.327 0.000
K83.4 Spasm of sphincter of Oddi
0.673 0.327 0.000
K83.3 Fistula of bile duct
0.673 0.327 0.000
K83.2 Perforation of bile duct
0.673 0.327 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.672 0.328 0.000
K86.2 Cyst of pancreas
0.672 0.328 0.000
S32 Fracture of lumbar spine and pelvis
0.672 0.328 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.672 0.328 0.000
S61.1 Open wound of finger(s) with damage to nail
0.670 0.330 0.000
M25.7 Osteophyte
0.670 0.330 0.000
S65 Injury of blood vessels at wrist and hand level
0.669 0.331 0.000
M23.3 Other meniscus derangements
0.668 0.331 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.667 0.332 0.000
C56 Malignant neoplasm of ovary
0.667 0.333 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.666 0.334 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.666 0.334 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.666 0.334 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.666 0.334 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.666 0.334 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.666 0.334 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.666 0.334 0.000
B48 Other mycoses, not elsewhere classified
0.666 0.334 0.000
B47 Mycetoma
0.666 0.334 0.000
B46 Zygomycosis
0.666 0.334 0.000
B45 Cryptococcosis
0.666 0.334 0.000
B44 Aspergillosis
0.666 0.334 0.000
B43 Chromomycosis and phaeomycotic abscess
0.666 0.334 0.000
B42 Sporotrichosis
0.666 0.334 0.000
B41 Paracoccidioidomycosis
0.666 0.334 0.000
B40 Blastomycosis
0.666 0.334 0.000
B39 Histoplasmosis
0.666 0.334 0.000
B38 Coccidioidomycosis
0.666 0.334 0.000
B36 Other superficial mycoses
0.666 0.334 0.000
B35 Dermatophytosis
0.666 0.334 0.000
B49 Unspecified mycosis
0.666 0.334 0.000
C50 Malignant neoplasm of breast
0.666 0.334 0.000
W20-W49 Exposure to inanimate mechanical forces
0.665 0.335 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.665 0.335 0.000
K86.8 Other specified diseases of pancreas
0.665 0.335 0.000
M23.4 Loose body in knee
0.665 0.335 0.000
R26.0 Ataxic gait
0.664 0.336 0.000
S20-S29 Injuries to the thorax
0.664 0.336 0.000
K29.9 Gastroduodenitis, unspecified
0.663 0.337 0.000
R63.6 Insufficient intake of food and water due to self neglect
0.663 0.337 0.000
R63.5 Abnormal weight gain
0.663 0.337 0.000
R63.3 Feeding difficulties and mismanagement
0.663 0.337 0.000
R63.2 Polyphagia
0.663 0.337 0.000
R63.1 Polydipsia
0.663 0.337 0.000
K22.1 Ulcer of oesophagus
0.663 0.337 0.000
V10-V19 Pedal cyclist injured in transport accident
0.661 0.339 0.000
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.661 0.339 0.000
Y52 Agents primarily affecting the cardiovascular system
0.661 0.339 0.000
M79.64 Pain in limb (Hand)
0.660 0.340 0.000
D72 Other disorders of white blood cells
0.660 0.340 0.000
R15 Faecal incontinence
0.659 0.341 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.659 0.341 0.000
M65 Synovitis and tenosynovitis
0.659 0.341 0.000
S82.3 Fracture of lower end of tibia
0.659 0.341 0.000
B99 Other and unspecified infectious diseases
0.658 0.342 0.000
C67 Malignant neoplasm of bladder
0.657 0.343 0.000
R94 Abnormal results of function studies
0.656 0.344 0.000
M07.3 Other psoriatic arthropathies
0.655 0.345 0.000
R42 Dizziness and giddiness
0.654 0.346 0.000
S82.6 Fracture of lateral malleolus
0.654 0.346 0.000
M48 Other spondylopathies
0.654 0.346 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.653 0.347 0.000
V80-V89 Other land transport accidents
0.653 0.347 0.000
S62.8 Fracture of other and unspecified parts of wrist and hand
0.653 0.347 0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)
0.653 0.347 0.000
R52.9 Pain, unspecified
0.652 0.347 0.000
R93.6 Abnormal findings on diagnostic imaging of limbs
0.651 0.349 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.651 0.349 0.000
L43 Lichen planus
0.651 0.349 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.651 0.349 0.000
K83.1 Obstruction of bile duct
0.650 0.349 0.000
L27 Dermatitis due to substances taken internally
0.650 0.349 0.000
K29.4 Chronic atrophic gastritis
0.650 0.350 0.000
S61.0 Open wound of finger(s) without damage to nail
0.648 0.352 0.000
M13.93 Arthritis, unspecified (Forearm)
0.647 0.353 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.647 0.353 0.000
L03.0 Cellulitis of finger and toe
0.647 0.353 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.647 0.353 0.000
L03.2 Cellulitis of face
0.646 0.354 0.000
T90 Sequelae of injuries of head
0.645 0.355 0.000
S50-S59 Injuries to the elbow and forearm
0.645 0.355 0.000
R55 Syncope and collapse
0.644 0.356 0.000
M35 Other systemic involvement of connective tissue
0.643 0.357 0.000
M99 Biomechanical lesions, not elsewhere classified
0.643 0.357 0.000
U80 Agent resistant to penicillin and related antibiotics
0.643 0.357 0.000
M94 Other disorders of cartilage
0.642 0.358 0.000
R40.2 Coma, unspecified
0.642 0.358 0.000
Y43 Primarily systemic agents
0.642 0.358 0.000
L53 Other erythematous conditions
0.641 0.359 0.000
K66.9 Disorder of peritoneum, unspecified
0.640 0.360 0.000
K66.1 Haemoperitoneum
0.640 0.360 0.000
E55 Vitamin D deficiency
0.639 0.360 0.000
K86.0 Alcohol-induced chronic pancreatitis
0.639 0.360 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.639 0.361 0.000
K29.3 Chronic superficial gastritis
0.639 0.361 0.000
M67 Other disorders of synovium and tendon
0.637 0.363 0.000
C51 Malignant neoplasm of vulva
0.636 0.364 0.000
M13.94 Arthritis, unspecified (Hand)
0.636 0.364 0.000
J90-J94 Other diseases of pleura
0.635 0.365 0.000
K35 Acute appendicitis
0.635 0.365 0.000
C54 Malignant neoplasm of corpus uteri
0.635 0.365 0.000
M79.79 Fibromyalgia (Site unspecified)
0.634 0.366 0.000
S05 Injury of eye and orbit
0.633 0.367 0.000
L03.3 Cellulitis of trunk
0.633 0.367 0.000
A48 Other bacterial diseases, not elsewhere classified
0.633 0.367 0.000
A44 Bartonellosis
0.633 0.367 0.000
A43 Nocardiosis
0.633 0.367 0.000
A42 Actinomycosis
0.633 0.367 0.000
A40 Streptococcal septicaemia
0.633 0.367 0.000
A39 Meningococcal infection
0.633 0.367 0.000
A37 Whooping cough
0.633 0.367 0.000
A36 Diphtheria
0.633 0.367 0.000
A32 Listeriosis
0.633 0.367 0.000
A31 Infection due to other mycobacteria
0.633 0.367 0.000
A30 Leprosy [Hansen's disease]
0.633 0.367 0.000
A46 Erysipelas
0.633 0.367 0.000
A38 Scarlet fever
0.633 0.367 0.000
A35 Other tetanus
0.633 0.367 0.000
A34 Obstetrical tetanus
0.633 0.367 0.000
A33 Tetanus neonatorum
0.633 0.367 0.000
R40.0 Somnolence
0.633 0.367 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.632 0.368 0.000
R80 Isolated proteinuria
0.632 0.368 0.000
M93 Other osteochondropathies
0.632 0.368 0.000
R41.2 Retrograde amnesia
0.632 0.368 0.000
R41.1 Anterograde amnesia
0.632 0.368 0.000
R59.9 Enlarged lymph nodes, unspecified
0.631 0.369 0.000
B37.7 Candidal septicaemia
0.631 0.369 0.000
B37.6 Candidal endocarditis
0.631 0.369 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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