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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75080821
log Bayes Factor = 15.089
Chromosome 1   position 112,264,671  (GRCh37) Explore rs75080821 on Ensembl!
Variant rs75080821 is part of Cluster X0040

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
0.997 0.003 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.996 0.004 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.995 0.005 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.995 0.005 0.000
F30-F39 Mood [affective] disorders
0.991 0.009 0.000
Chapter IX Diseases of the circulatory system
0.990 0.010 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.990 0.010 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.989 0.011 0.000
F32 Depressive episode
0.983 0.017 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.983 0.017 0.000
S00-S09 Injuries to the head
0.981 0.019 0.000
F10.0 Acute intoxication
0.967 0.033 0.000
F32.9 Depressive episode, unspecified
0.962 0.038 0.000
S01 Open wound of head
0.957 0.043 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.956 0.044 0.000
I20-I25 Ischaemic heart diseases
0.954 0.046 0.000
W00-W19 Falls
0.951 0.049 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.947 0.053 0.000
F10.2 Dependence syndrome
0.938 0.062 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.936 0.064 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.933 0.067 0.000
Chapter XXI Factors influencing health status and contact with health services
0.929 0.071 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.929 0.071 0.000
Chapter VI Diseases of the nervous system
0.928 0.072 0.000
Chapter VIII Diseases of the ear and mastoid process
0.917 0.083 0.000
S20-S29 Injuries to the thorax
0.910 0.090 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.910 0.090 0.000
R30-R39 Symptoms and signs involving the urinary system
0.907 0.093 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.904 0.096 0.000
O60-O75 Complications of labour and delivery
0.903 0.097 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.903 0.097 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.903 0.097 0.000
M80-M85 Disorders of bone density and structure
0.902 0.098 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.901 0.099 0.000
W19 Unspecified fall
0.900 0.100 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.894 0.106 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.888 0.112 0.000
M15-M19 Arthrosis
0.888 0.112 0.000
F10.1 Harmful use
0.885 0.115 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.885 0.115 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.885 0.115 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.882 0.118 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.881 0.119 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.877 0.123 0.000
F10.3 Withdrawal state
0.876 0.124 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.870 0.130 0.000
M45-M49 Spondylopathies
0.870 0.130 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.868 0.132 0.000
S60-S69 Injuries to the wrist and hand
0.867 0.133 0.000
S40-S49 Injuries to the shoulder and upper arm
0.867 0.133 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.864 0.136 0.000
Z47 Other orthopaedic follow-up care
0.864 0.136 0.000
I20 Angina pectoris
0.860 0.140 0.000
M16 Coxarthrosis [arthrosis of hip]
0.859 0.141 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.858 0.142 0.000
Z45 Adjustment and management of implanted device
0.851 0.149 0.000
R39 Other symptoms and signs involving the urinary system
0.849 0.151 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.845 0.155 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.844 0.156 0.000
O70 Perineal laceration during delivery
0.843 0.157 0.000
M16.9 Coxarthrosis, unspecified
0.842 0.158 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.841 0.159 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.840 0.160 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.840 0.160 0.000
S80-S89 Injuries to the knee and lower leg
0.840 0.160 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.839 0.161 0.000
M50-M54 Other dorsopathies
0.837 0.163 0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.836 0.164 0.000
S01.1 Open wound of eyelid and periocular area
0.835 0.165 0.000
I95 Hypotension
0.833 0.167 0.000
V10-V19 Pedal cyclist injured in transport accident
0.833 0.167 0.000
S01.8 Open wound of other parts of head
0.831 0.169 0.000
Chapter XI Diseases of the digestive system
0.829 0.171 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.821 0.179 0.000
I25 Chronic ischaemic heart disease
0.820 0.180 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.820 0.180 0.000
S90-S99 Injuries to the ankle and foot
0.818 0.182 0.000
Y45.0 Opioids and related analgesics
0.818 0.182 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.817 0.183 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.817 0.183 0.000
F33 Recurrent depressive disorder
0.814 0.186 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.814 0.186 0.000
Z45.2 Adjustment and management of vascular access device
0.808 0.192 0.000
L57.0 Actinic keratosis
0.807 0.193 0.000
Z50 Care involving use of rehabilitation procedures
0.806 0.194 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.805 0.195 0.000
S70-S79 Injuries to the hip and thigh
0.805 0.195 0.000
O70.1 Second degree perineal laceration during delivery
0.804 0.196 0.000
H80-H83 Diseases of inner ear
0.803 0.197 0.000
K90-K93 Other diseases of the digestive system
0.800 0.200 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.800 0.200 0.000
O00-O08 Pregnancy with abortive outcome
0.797 0.203 0.000
W19.2 School, other institution and public administrative area
0.795 0.205 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.795 0.205 0.000
S01.4 Open wound of cheek and temporomandibular area
0.793 0.207 0.000
M81 Osteoporosis without pathological fracture
0.792 0.207 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.792 0.208 0.000
I20.9 Angina pectoris, unspecified
0.792 0.208 0.000
Z49 Care involving dialysis
0.790 0.210 0.000
R50-R69 General symptoms and signs
0.790 0.210 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.789 0.211 0.000
S01.0 Open wound of scalp
0.789 0.211 0.000
Y83.8 Other surgical procedures
0.788 0.212 0.000
K92 Other diseases of digestive system
0.785 0.215 0.000
I95.9 Hypotension, unspecified
0.784 0.216 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.784 0.216 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.783 0.217 0.000
W19.4 Street and highway
0.783 0.217 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.782 0.218 0.000
I60-I69 Cerebrovascular diseases
0.782 0.218 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.781 0.219 0.000
Z48 Other surgical follow-up care
0.779 0.221 0.000
S00 Superficial injury of head
0.777 0.222 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.774 0.226 0.000
S42 Fracture of shoulder and upper arm
0.773 0.227 0.000
F03 Unspecified dementia
0.771 0.229 0.000
S06 Intracranial injury
0.771 0.229 0.000
O72 Postpartum haemorrhage
0.767 0.233 0.000
Z43 Attention to artificial openings
0.767 0.233 0.000
I21 Acute myocardial infarction
0.767 0.233 0.000
R26 Abnormalities of gait and mobility
0.766 0.234 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.765 0.235 0.000
R39.1 Other difficulties with micturition
0.762 0.238 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.761 0.239 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.761 0.239 0.000
F41 Other anxiety disorders
0.760 0.239 0.000
I25.1 Atherosclerotic heart disease
0.760 0.240 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.759 0.241 0.000
M80 Osteoporosis with pathological fracture
0.759 0.241 0.000
K92.1 Melaena
0.758 0.242 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.758 0.242 0.000
K65-K67 Diseases of peritoneum
0.755 0.245 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.755 0.245 0.000
M47 Spondylosis
0.754 0.246 0.000
Chapter I Certain infectious and parasitic diseases
0.754 0.246 0.000
S01.3 Open wound of ear
0.754 0.246 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.753 0.247 0.000
R33 Retention of urine
0.752 0.248 0.000
F60-F69 Disorders of adult personality and behaviour
0.751 0.249 0.000
S02 Fracture of skull and facial bones
0.751 0.249 0.000
G57 Mononeuropathies of lower limb
0.750 0.250 0.000
X60-X84 Intentional self-harm
0.749 0.251 0.000
Z50.8 Care involving use of rehabilitation procedures
0.749 0.251 0.000
K92.0 Haematemesis
0.749 0.251 0.000
W20-W49 Exposure to inanimate mechanical forces
0.748 0.251 0.000
H65-H75 Diseases of middle ear and mastoid
0.747 0.253 0.000
M00-M03 Infectious arthropathies
0.747 0.253 0.000
Chapter XXII Codes for special purposes
0.747 0.253 0.000
R31 Unspecified haematuria
0.746 0.254 0.000
M40-M43 Deforming dorsopathies
0.746 0.254 0.000
R55 Syncope and collapse
0.744 0.256 0.000
S20 Superficial injury of thorax
0.742 0.258 0.000
F99-F99 Unspecified mental disorder
0.742 0.258 0.000
F43 Reaction to severe stress, and adjustment disorders
0.741 0.259 0.000
W13 Fall from, out of or through building or structure
0.740 0.260 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.739 0.261 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.738 0.262 0.000
Y57 Other and unspecified drugs and medicaments
0.738 0.262 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.737 0.263 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.736 0.264 0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.735 0.265 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.731 0.269 0.000
M65-M68 Disorders of synovium and tendon
0.731 0.269 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.731 0.269 0.000
D68 Other coagulation defects
0.731 0.269 0.000
M18 Arthrosis of first carpometacarpal joint
0.731 0.269 0.000
W10 Fall on and from stairs and steps
0.730 0.270 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.729 0.271 0.000
M86-M90 Other osteopathies
0.729 0.271 0.000
I73 Other peripheral vascular diseases
0.728 0.272 0.000
T79-T79 Certain early complications of trauma
0.727 0.273 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.727 0.273 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.726 0.273 0.000
T82.1 Mechanical complication of cardiac electronic device
0.725 0.275 0.000
D60-D64 Aplastic and other anaemias
0.725 0.275 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.724 0.276 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.724 0.276 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.724 0.276 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.723 0.277 0.000
L03 Cellulitis
0.722 0.278 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.721 0.279 0.000
H90-H95 Other disorders of ear
0.721 0.279 0.000
G90-G99 Other disorders of the nervous system
0.719 0.281 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.719 0.281 0.000
I24 Other acute ischaemic heart diseases
0.719 0.281 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F80-F89 Disorders of psychological development
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
H81 Disorders of vestibular function
0.717 0.283 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.715 0.285 0.000
G30-G32 Other degenerative diseases of the nervous system
0.715 0.285 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.715 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.715 0.285 0.000
Y10-Y34 Event of undetermined intent
0.715 0.285 0.000
Y00-Y09 Assault
0.715 0.285 0.000
X85-X99 Assault
0.715 0.285 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.715 0.285 0.000
X50-X57 Overexertion, travel and privation
0.715 0.285 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.715 0.285 0.000
X30-X39 Exposure to forces of nature
0.715 0.285 0.000
X20-X29 Contact with venomous animals and plants
0.715 0.285 0.000
X10-X19 Contact with heat and hot substances
0.715 0.285 0.000
X00-X09 Exposure to smoke, fire and flames
0.715 0.285 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.715 0.285 0.000
W75-W84 Other accidental threats to breathing
0.715 0.285 0.000
W65-W74 Accidental drowning and submersion
0.715 0.285 0.000
W50-W64 Exposure to animate mechanical forces
0.715 0.285 0.000
V98-V99 Other and unspecified transport accidents
0.715 0.285 0.000
V95-V97 Air and space transport accidents
0.715 0.285 0.000
V90-V94 Water transport accidents
0.715 0.285 0.000
V80-V89 Other land transport accidents
0.715 0.285 0.000
V70-V79 Bus occupant injured in transport accident
0.715 0.285 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.715 0.285 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.715 0.285 0.000
V40-V49 Car occupant injured in transport accident
0.715 0.285 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.715 0.285 0.000
V20-V29 Motorcycle rider injured in transport accident
0.715 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.285 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.714 0.286 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.714 0.286 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.714 0.286 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.714 0.286 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.714 0.286 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.714 0.286 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.714 0.286 0.000
F11 Mental and behavioural disorders due to use of opioids
0.714 0.286 0.000
M81.9 Osteoporosis, unspecified
0.714 0.286 0.000
F00 Dementia in Alzheimer's disease
0.714 0.286 0.000
T87 Complications peculiar to reattachment and amputation
0.714 0.286 0.000
T86 Failure and rejection of transplanted organs and tissues
0.714 0.286 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.714 0.286 0.000
F10.9 Unspecified mental and behavioural disorder
0.713 0.286 0.000
F10.8 Other mental and behavioural disorders
0.713 0.286 0.000
F10.7 Residual and late-onset psychotic disorder
0.713 0.286 0.000
F10.6 Amnesic syndrome
0.713 0.286 0.000
F10.5 Psychotic disorder
0.713 0.286 0.000
F10.4 Withdrawal state with delirium
0.713 0.286 0.000
M05-M14 Inflammatory polyarthropathies
0.713 0.287 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.712 0.288 0.000
O80-O84 Delivery
0.712 0.288 0.000
F38 Other mood [affective] disorders
0.711 0.289 0.000
F34 Persistent mood [affective] disorders
0.711 0.289 0.000
F30 Manic episode
0.711 0.289 0.000
F39 Unspecified mood [affective] disorder
0.711 0.289 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.711 0.289 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.711 0.289 0.000
I00-I02 Acute rheumatic fever
0.710 0.290 0.000
R87 Abnormal findings in specimens from female genital organs
0.710 0.290 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.710 0.290 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.709 0.291 0.000
M91-M94 Chondropathies
0.709 0.291 0.000
M60-M63 Disorders of muscles
0.709 0.291 0.000
W19.9 Unspecified place
0.709 0.291 0.000
I22 Subsequent myocardial infarction
0.708 0.292 0.000
F42 Obsessive-compulsive disorder
0.708 0.292 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.707 0.293 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.707 0.293 0.000
M48 Other spondylopathies
0.706 0.294 0.000
F32.8 Other depressive episodes
0.705 0.295 0.000
F32.1 Moderate depressive episode
0.705 0.295 0.000
F32.0 Mild depressive episode
0.705 0.295 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.705 0.295 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.705 0.295 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.705 0.295 0.000
T82.3 Mechanical complication of other vascular grafts
0.705 0.295 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.705 0.295 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.705 0.295 0.000
S22.4 Multiple fractures of ribs
0.705 0.295 0.000
T66-T78 Other and unspecified effects of external causes
0.704 0.296 0.000
K65 Peritonitis
0.704 0.296 0.000
S08 Traumatic amputation of part of head
0.704 0.296 0.000
S07 Crushing injury of head
0.704 0.296 0.000
S05 Injury of eye and orbit
0.704 0.296 0.000
S04 Injury of cranial nerves
0.704 0.296 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.704 0.296 0.000
M50 Cervical disk disorders
0.703 0.297 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.703 0.297 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.702 0.298 0.000
R73 Elevated blood glucose level
0.702 0.298 0.000
I78 Diseases of capillaries
0.700 0.300 0.000
I80 Phlebitis and thrombophlebitis
0.699 0.301 0.000
G70-G73 Diseases of myoneural junction and muscle
0.699 0.301 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.699 0.301 0.000
I77 Other disorders of arteries and arterioles
0.699 0.301 0.000
S82 Fracture of lower leg, including ankle
0.697 0.303 0.000
R41.0 Disorientation, unspecified
0.696 0.304 0.000
S62 Fracture at wrist and hand level
0.695 0.305 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.694 0.305 0.000
M20-M25 Other joint disorders
0.694 0.306 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.693 0.307 0.000
T43.2 Other and unspecified antidepressants
0.692 0.308 0.000
O02 Other abnormal products of conception
0.691 0.309 0.000
F33.9 Recurrent depressive disorder, unspecified
0.687 0.313 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.686 0.313 0.000
Y44 Agents primarily affecting blood constituents
0.686 0.314 0.000
S01.7 Multiple open wounds of head
0.686 0.314 0.000
S01.5 Open wound of lip and oral cavity
0.686 0.314 0.000
S01.2 Open wound of nose
0.686 0.314 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.686 0.314 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.686 0.314 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.686 0.314 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.686 0.314 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.686 0.314 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.686 0.314 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.686 0.314 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.686 0.314 0.000
T36 Poisoning by systemic antibiotics
0.686 0.314 0.000
S42.3 Fracture of shaft of humerus
0.685 0.315 0.000
I23 Certain current complications following acute myocardial infarction
0.684 0.316 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.682 0.318 0.000
M51 Other intervertebral disk disorders
0.682 0.318 0.000
W18 Other fall on same level
0.682 0.318 0.000
W17 Other fall from one level to another
0.682 0.318 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.682 0.318 0.000
W15 Fall from cliff
0.682 0.318 0.000
W14 Fall from tree
0.682 0.318 0.000
W12 Fall on and from scaffolding
0.682 0.318 0.000
W11 Fall on and from ladder
0.682 0.318 0.000
W09 Fall involving playground equipment
0.682 0.318 0.000
W08 Fall involving other furniture
0.682 0.318 0.000
W07 Fall involving chair
0.682 0.318 0.000
W06 Fall involving bed
0.682 0.318 0.000
W05 Fall involving wheelchair
0.682 0.318 0.000
W04 Fall while being carried or supported by other persons
0.682 0.318 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.682 0.318 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.682 0.318 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.682 0.318 0.000
W00 Fall on same level involving ice and snow
0.682 0.318 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.681 0.319 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.681 0.319 0.000
M16.1 Other primary coxarthrosis
0.680 0.320 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.680 0.320 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.679 0.321 0.000
R25 Abnormal involuntary movements
0.679 0.321 0.000
R74 Abnormal serum enzyme levels
0.678 0.321 0.000
Z48.8 Other specified surgical follow-up care
0.678 0.322 0.000
I21.4 Acute subendocardial myocardial infarction
0.677 0.323 0.000
S67 Crushing injury of wrist and hand
0.677 0.323 0.000
I74 Arterial embolism and thrombosis
0.676 0.323 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.676 0.324 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.675 0.325 0.000
L50-L54 Urticaria and erythema
0.675 0.325 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.674 0.326 0.000
I67 Other cerebrovascular diseases
0.674 0.326 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.673 0.326 0.000
D80-D89 Certain disorders involving the immune mechanism
0.671 0.329 0.000
Y59 Other and unspecified vaccines and biological substances
0.671 0.329 0.000
Y58 Bacterial vaccines
0.671 0.329 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.671 0.329 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.671 0.329 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.671 0.329 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.671 0.329 0.000
Y52 Agents primarily affecting the cardiovascular system
0.671 0.329 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.671 0.329 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.671 0.329 0.000
Y48 Anaesthetics and therapeutic gases
0.671 0.329 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.671 0.329 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.671 0.329 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.671 0.329 0.000
G57.6 Lesion of plantar nerve
0.669 0.331 0.000
O85-O92 Complications predominantly related to the puerperium
0.669 0.331 0.000
S27 Injury of other and unspecified intrathoracic organs
0.667 0.332 0.000
I10-I15 Hypertensive diseases
0.667 0.333 0.000
F01 Vascular dementia
0.666 0.334 0.000
I62 Other nontraumatic intracranial haemorrhage
0.666 0.334 0.000
L10-L14 Bullous disorders
0.666 0.334 0.000
S72 Fracture of femur
0.665 0.335 0.000
I70 Atherosclerosis
0.665 0.335 0.000
H72 Perforation of tympanic membrane
0.665 0.335 0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity
0.661 0.339 0.000
Z39 Postpartum care and examination
0.661 0.339 0.000
S01.9 Open wound of head, part unspecified
0.659 0.341 0.000
L05 Pilonidal cyst
0.659 0.341 0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.658 0.341 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.658 0.342 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.658 0.342 0.000
R45 Symptoms and signs involving emotional state
0.657 0.342 0.000
S40 Superficial injury of shoulder and upper arm
0.657 0.342 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.657 0.343 0.000
Z49.1 Extracorporeal dialysis
0.655 0.345 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.654 0.346 0.000
S09 Other and unspecified injuries of head
0.653 0.347 0.000
S29 Other and unspecified injuries of thorax
0.652 0.347 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.652 0.347 0.000
S26 Injury of heart
0.652 0.347 0.000
S25 Injury of blood vessels of thorax
0.652 0.347 0.000
S24 Injury of nerves and spinal cord at thorax level
0.652 0.347 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.652 0.347 0.000
S21 Open wound of thorax
0.652 0.347 0.000
S92 Fracture of foot, except ankle
0.652 0.348 0.000
Z54 Convalescence
0.652 0.348 0.000
Z52 Donors of organs and tissues
0.652 0.348 0.000
Z44 Fitting and adjustment of external prosthetic device
0.652 0.348 0.000
R36 Urethral discharge
0.650 0.350 0.000
R34 Anuria and oliguria
0.650 0.350 0.000
F23 Acute and transient psychotic disorders
0.650 0.350 0.000
B35-B49 Mycoses
0.650 0.350 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.650 0.350 0.000
Z49.0 Preparatory care for dialysis
0.649 0.351 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.648 0.351 0.000
M47.9 Spondylosis, unspecified
0.648 0.352 0.000
O74 Complications of anaesthesia during labour and delivery
0.647 0.352 0.000
O73 Retained placenta and membranes, without haemorrhage
0.647 0.352 0.000
O71 Other obstetric trauma
0.647 0.352 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.647 0.352 0.000
O66 Other obstructed labour
0.647 0.352 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.647 0.352 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.647 0.352 0.000
O62 Abnormalities of forces of labour
0.647 0.352 0.000
O61 Failed induction of labour
0.647 0.352 0.000
O60 Preterm delivery
0.647 0.352 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.647 0.353 0.000
I99 Other and unspecified disorders of circulatory system
0.647 0.353 0.000
K65.9 Peritonitis, unspecified
0.647 0.353 0.000
D55-D59 Haemolytic anaemias
0.647 0.353 0.000
M85 Other disorders of bone density and structure
0.647 0.353 0.000
M84 Disorders of continuity of bone
0.647 0.353 0.000
M83 Adult osteomalacia
0.647 0.353 0.000
M82 Osteoporosis in diseases classified elsewhere
0.647 0.353 0.000
Z63 Other problems related to primary support group, including family circumstances
0.647 0.353 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.646 0.353 0.000
F48 Other neurotic disorders
0.646 0.354 0.000
F45 Somatoform disorders
0.646 0.354 0.000
F44 Dissociative [conversion] disorders
0.646 0.354 0.000
O69.2 Labour and delivery complicated by other cord entanglement
0.645 0.354 0.000
W19.8 Other specified place
0.645 0.354 0.000
W19.5 Trade and service area
0.645 0.354 0.000
W19.0 Home
0.645 0.354 0.000
W19.7 Farm
0.645 0.354 0.000
W19.6 Industrial and construction area
0.645 0.354 0.000
W19.3 Sports and athletics area
0.645 0.354 0.000
W19.1 Residential institution
0.645 0.354 0.000
Y40 Systemic antibiotics
0.645 0.355 0.000
R40 Somnolence, stupor and coma
0.645 0.355 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.644 0.356 0.000
S89 Other and unspecified injuries of lower leg
0.644 0.356 0.000
H60-H62 Diseases of external ear
0.644 0.356 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.643 0.357 0.000
H81.0 Meniere's disease
0.642 0.358 0.000
Z43.6 Attention to other artificial openings of urinary tract
0.642 0.358 0.000
D68.5 Primary Thrombophilia
0.641 0.359 0.000
O04 Medical abortion
0.641 0.359 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.641 0.359 0.000
Y45.8 Other analgesics and antipyretics
0.641 0.359 0.000
Y45.5 4-Aminophenol derivatives
0.641 0.359 0.000
Y45.4 Antirheumatics
0.641 0.359 0.000
Y45.2 Propionic acid derivatives
0.641 0.359 0.000
Y45.1 Salicylates
0.641 0.359 0.000
S00.8 Superficial injury of other parts of head
0.640 0.360 0.000
R05 Cough
0.640 0.360 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.640 0.360 0.000
I05-I09 Chronic rheumatic heart diseases
0.639 0.360 0.000
M25 Other joint disorders, not elsewhere classified
0.639 0.361 0.000
Chapter X Diseases of the respiratory system
0.639 0.361 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.638 0.361 0.000
D69 Purpura and other haemorrhagic conditions
0.638 0.362 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.638 0.362 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.637 0.363 0.000
I72 Other aneurysm
0.637 0.363 0.000
R80 Isolated proteinuria
0.637 0.363 0.000
M15 Polyarthrosis
0.637 0.363 0.000
F20 Schizophrenia
0.636 0.363 0.000
I20.0 Unstable angina
0.636 0.364 0.000
S91 Open wound of ankle and foot
0.636 0.364 0.000
R73.0 Abnormal glucose tolerance test
0.635 0.365 0.000
R32 Unspecified urinary incontinence
0.635 0.365 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.635 0.365 0.000
F02 Dementia in other diseases classified elsewhere
0.635 0.365 0.000
F09 Unspecified organic or symptomatic mental disorder
0.635 0.365 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.635 0.365 0.000
R27 Other lack of coordination
0.634 0.365 0.000
T39.1 4-Aminophenol derivatives
0.633 0.367 0.000
R47-R49 Symptoms and signs involving speech and voice
0.633 0.367 0.000
S22.40 Multiple fractures of ribs (closed)
0.633 0.367 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.633 0.367 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.633 0.367 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.633 0.367 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.633 0.367 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.633 0.367 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.633 0.367 0.000
F40 Phobic anxiety disorders
0.632 0.367 0.000
L20-L30 Dermatitis and eczema
0.632 0.368 0.000
Z45.1 Adjustment and management of infusion pump
0.632 0.368 0.000
R53 Malaise and fatigue
0.631 0.369 0.000
F31 Bipolar affective disorder
0.631 0.369 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.630 0.370 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.630 0.370 0.000
M53 Other dorsopathies, not elsewhere classified
0.629 0.371 0.000
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.629 0.371 0.000
L58 Radiodermatitis
0.629 0.371 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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