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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75128130
log Bayes Factor = 11.4347
Chromosome 13   position 33,783,123  (GRCh37) Explore rs75128130 on Ensembl!
Variant rs75128130 is part of Cluster X0026

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
0.999 0.001 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.995 0.005 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.994 0.006 0.000
Chapter XXI Factors influencing health status and contact with health services
0.994 0.006 0.000
Chapter VI Diseases of the nervous system
0.992 0.008 0.000
Chapter I Certain infectious and parasitic diseases
0.992 0.008 0.000
Chapter II Neoplasms
0.991 0.009 0.000
Chapter VII Diseases of the eye and adnexa
0.988 0.012 0.000
G40-G47 Episodic and paroxysmal disorders
0.985 0.015 0.000
B95-B98 Bacterial, viral and other infectious agents
0.984 0.016 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.983 0.017 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.982 0.018 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.981 0.019 0.000
Z85 Personal history of malignant neoplasm
0.980 0.020 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.974 0.026 0.000
I25.2 Old myocardial infarction
0.974 0.026 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.973 0.027 0.000
T81 Complications of procedures, not elsewhere classified
0.971 0.029 0.000
Z93 Artificial opening status
0.971 0.029 0.000
Z86 Personal history of certain other diseases
0.970 0.030 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.966 0.034 0.000
M50-M54 Other dorsopathies
0.962 0.038 0.000
Z96 Presence of other functional implants
0.960 0.040 0.000
G40 Epilepsy
0.960 0.040 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.954 0.046 0.000
M05-M14 Inflammatory polyarthropathies
0.953 0.047 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.953 0.047 0.000
M54 Dorsalgia
0.952 0.048 0.000
Chapter XX External causes of morbidity and mortality
0.946 0.054 0.000
Z98 Other postsurgical states
0.938 0.062 0.000
Z96.8 Presence of other specified functional implants
0.938 0.062 0.000
H30-H36 Disorders of choroid and retina
0.938 0.062 0.000
M06 Other rheumatoid arthritis
0.937 0.063 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.934 0.066 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.934 0.066 0.000
Chapter VIII Diseases of the ear and mastoid process
0.932 0.068 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.932 0.068 0.000
G47 Sleep disorders
0.931 0.069 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.931 0.069 0.000
I73 Other peripheral vascular diseases
0.930 0.070 0.000
Z94 Transplanted organ and tissue status
0.927 0.073 0.000
M06.9 Rheumatoid arthritis, unspecified
0.926 0.074 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.924 0.076 0.000
Z93.2 Ileostomy status
0.921 0.079 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.915 0.085 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.909 0.091 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.905 0.095 0.000
H33 Retinal detachments and breaks
0.902 0.098 0.000
Chapter XXII Codes for special purposes
0.900 0.100 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.898 0.102 0.000
H65-H75 Diseases of middle ear and mastoid
0.897 0.103 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.895 0.105 0.000
I73.9 Peripheral vascular disease, unspecified
0.893 0.107 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.889 0.111 0.000
G40.9 Epilepsy, unspecified
0.884 0.116 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.881 0.119 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.881 0.119 0.000
I60-I69 Cerebrovascular diseases
0.879 0.121 0.000
R07 Pain in throat and chest
0.876 0.124 0.000
M54.3 Sciatica
0.875 0.125 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.873 0.127 0.000
I22 Subsequent myocardial infarction
0.873 0.127 0.000
C64-C68 Malignant neoplasms of urinary tract
0.872 0.128 0.000
R07.4 Chest pain, unspecified
0.869 0.131 0.000
Z98.8 Other specified postsurgical states
0.868 0.132 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.867 0.133 0.000
H43-H45 Disorders of vitreous body and globe
0.865 0.135 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.860 0.140 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.859 0.141 0.000
Z93.3 Colostomy status
0.858 0.142 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.858 0.142 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.856 0.144 0.000
M54.1 Radiculopathy
0.849 0.151 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.848 0.152 0.000
Z96.1 Presence of intraocular lens
0.848 0.152 0.000
C91 Lymphoid leukaemia
0.847 0.153 0.000
I63 Cerebral infarction
0.847 0.153 0.000
H20 Iridocyclitis
0.847 0.153 0.000
M45-M49 Spondylopathies
0.847 0.153 0.000
I20 Angina pectoris
0.846 0.154 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.845 0.155 0.000
Z85.4 Personal history of malignant neoplasm of genital organs
0.844 0.156 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.841 0.159 0.000
Z89 Acquired absence of limb
0.840 0.160 0.000
Z85.6 Personal history of leukaemia
0.836 0.164 0.000
G47.9 Sleep disorder, unspecified
0.836 0.164 0.000
M54.5 Low back pain
0.835 0.165 0.000
T86 Failure and rejection of transplanted organs and tissues
0.834 0.166 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.830 0.170 0.000
Z94.8 Other transplanted organ and tissue status
0.830 0.170 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.830 0.170 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.827 0.173 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.822 0.177 0.000
G70-G73 Diseases of myoneural junction and muscle
0.822 0.178 0.000
A00-A09 Intestinal infectious diseases
0.821 0.179 0.000
T79-T79 Certain early complications of trauma
0.820 0.180 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.819 0.181 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.818 0.182 0.000
I21 Acute myocardial infarction
0.817 0.183 0.000
I20.0 Unstable angina
0.817 0.183 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.816 0.184 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.813 0.187 0.000
Z98.1 Arthrodesis status
0.812 0.188 0.000
C67 Malignant neoplasm of bladder
0.812 0.188 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.811 0.189 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.811 0.189 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.810 0.189 0.000
Z96.7 Presence of other bone and tendon implants
0.808 0.192 0.000
H33.2 Serous retinal detachment
0.806 0.194 0.000
Y43 Primarily systemic agents
0.805 0.194 0.000
H20.9 Iridocyclitis, unspecified
0.805 0.195 0.000
A30-A49 Other bacterial diseases
0.804 0.196 0.000
Q21 Congenital malformations of cardiac septa
0.801 0.199 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.799 0.201 0.000
S60-S69 Injuries to the wrist and hand
0.799 0.201 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.799 0.201 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.798 0.202 0.000
M54.39 Sciatica (Site unspecified)
0.797 0.203 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.794 0.206 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.794 0.206 0.000
I05-I09 Chronic rheumatic heart diseases
0.794 0.206 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.790 0.209 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.790 0.210 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.790 0.210 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.789 0.211 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.789 0.211 0.000
H10-H13 Disorders of conjunctiva
0.788 0.212 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.784 0.216 0.000
R07.2 Precordial pain
0.784 0.216 0.000
H33.5 Other retinal detachments
0.784 0.216 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.782 0.218 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.782 0.218 0.000
B25-B34 Other viral diseases
0.779 0.221 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.779 0.221 0.000
H72 Perforation of tympanic membrane
0.779 0.221 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.778 0.222 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.777 0.223 0.000
G47.4 Narcolepsy and cataplexy
0.776 0.224 0.000
Chapter XI Diseases of the digestive system
0.775 0.225 0.000
M53 Other dorsopathies, not elsewhere classified
0.774 0.226 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.772 0.228 0.000
H66 Suppurative and unspecified otitis media
0.771 0.229 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.770 0.230 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.770 0.230 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.769 0.231 0.000
M10 Gout
0.769 0.231 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.767 0.233 0.000
H74 Other disorders of middle ear and mastoid
0.767 0.233 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.766 0.234 0.000
C85.1 B-cell lymphoma, unspecified
0.763 0.237 0.000
Q21.1 Atrial septal defect
0.762 0.238 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.762 0.238 0.000
I70 Atherosclerosis
0.762 0.238 0.000
Z94.0 Kidney transplant status
0.760 0.240 0.000
I74 Arterial embolism and thrombosis
0.760 0.240 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.760 0.240 0.000
M54.2 Cervicalgia
0.758 0.242 0.000
R79 Other abnormal findings of blood chemistry
0.758 0.242 0.000
H90-H95 Other disorders of ear
0.758 0.242 0.000
Z84 Family history of other conditions
0.757 0.243 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.755 0.245 0.000
M51 Other intervertebral disk disorders
0.754 0.246 0.000
D46 Myelodysplastic syndromes
0.753 0.247 0.000
C34 Malignant neoplasm of bronchus and lung
0.752 0.248 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.751 0.249 0.000
G90-G99 Other disorders of the nervous system
0.751 0.249 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.750 0.250 0.000
G30-G32 Other degenerative diseases of the nervous system
0.750 0.250 0.000
I21.4 Acute subendocardial myocardial infarction
0.748 0.252 0.000
H33.0 Retinal detachment with retinal break
0.748 0.252 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.748 0.252 0.000
U80 Agent resistant to penicillin and related antibiotics
0.748 0.252 0.000
W20-W49 Exposure to inanimate mechanical forces
0.746 0.254 0.000
T82.1 Mechanical complication of cardiac electronic device
0.746 0.254 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.743 0.257 0.000
T00-T07 Injuries involving multiple body regions
0.743 0.257 0.000
Z93.6 Other artificial openings of urinary tract status
0.743 0.257 0.000
C88 Malignant immunoproliferative diseases
0.742 0.258 0.000
R02 Gangrene, not elsewhere classified
0.742 0.258 0.000
H35 Other retinal disorders
0.742 0.258 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.741 0.259 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.741 0.259 0.000
M54.16 Radiculopathy (Lumbar region)
0.741 0.259 0.000
Y57 Other and unspecified drugs and medicaments
0.740 0.260 0.000
I77 Other disorders of arteries and arterioles
0.740 0.260 0.000
R26 Abnormalities of gait and mobility
0.738 0.262 0.000
Q50-Q56 Congenital malformations of genital organs
0.736 0.264 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.734 0.266 0.000
G41 Status epilepticus
0.734 0.266 0.000
H43 Disorders of vitreous body
0.734 0.266 0.000
I71 Aortic aneurysm and dissection
0.733 0.267 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.733 0.267 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.733 0.267 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.732 0.267 0.000
C09 Malignant neoplasm of tonsil
0.730 0.270 0.000
C67.9 Bladder, unspecified
0.730 0.270 0.000
D00-D09 In situ neoplasms
0.729 0.271 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.729 0.271 0.000
Z93.1 Gastrostomy status
0.728 0.272 0.000
Y43.3 Other antineoplastic drugs
0.727 0.273 0.000
I25.5 Ischaemic cardiomyopathy
0.726 0.274 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.725 0.275 0.000
Z94.7 Corneal transplant status
0.725 0.275 0.000
K90-K93 Other diseases of the digestive system
0.724 0.276 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.724 0.276 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.723 0.276 0.000
I21.9 Acute myocardial infarction, unspecified
0.723 0.277 0.000
H53-H54 Visual disturbances and blindness
0.723 0.277 0.000
M54.4 Lumbago with sciatica
0.723 0.277 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.723 0.277 0.000
I25.3 Aneurysm of heart
0.722 0.278 0.000
K83 Other diseases of biliary tract
0.722 0.278 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.721 0.279 0.000
H66.9 Otitis media, unspecified
0.721 0.279 0.000
S10-S19 Injuries to the neck
0.719 0.280 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.719 0.281 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.718 0.282 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.718 0.282 0.000
I73.0 Raynaud's syndrome
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
R06 Abnormalities of breathing
0.717 0.283 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.717 0.283 0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.716 0.283 0.000
I25.6 Silent myocardial ischaemia
0.716 0.284 0.000
I25.4 Coronary artery aneurysm
0.716 0.284 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.714 0.286 0.000
Z81 Family history of mental and behavioural disorders
0.713 0.287 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.712 0.288 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.711 0.289 0.000
B99-B99 Other infectious diseases
0.711 0.289 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.711 0.289 0.000
B65-B83 Helminthiases
0.711 0.289 0.000
B50-B64 Protozoal diseases
0.711 0.289 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.711 0.289 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.711 0.289 0.000
A80-A89 Viral infections of the central nervous system
0.711 0.289 0.000
A75-A79 Rickettsioses
0.711 0.289 0.000
A70-A74 Other diseases caused by chlamydiae
0.711 0.289 0.000
A65-A69 Other spirochaetal diseases
0.711 0.289 0.000
A20-A28 Certain zoonotic bacterial diseases
0.711 0.289 0.000
A15-A19 Tuberculosis
0.711 0.289 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.711 0.289 0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.711 0.289 0.000
W00-W19 Falls
0.710 0.290 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.710 0.290 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.710 0.290 0.000
S20-S29 Injuries to the thorax
0.710 0.290 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.710 0.290 0.000
M00-M03 Infectious arthropathies
0.710 0.290 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.709 0.291 0.000
H70 Mastoiditis and related conditions
0.709 0.291 0.000
M54.59 Low back pain (Site unspecified)
0.708 0.292 0.000
R07.0 Pain in throat
0.708 0.292 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.706 0.294 0.000
T33-T35 Frostbite
0.705 0.295 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.705 0.295 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.705 0.295 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.704 0.295 0.000
M70-M79 Other soft tissue disorders
0.704 0.296 0.000
M91-M94 Chondropathies
0.704 0.296 0.000
M60-M63 Disorders of muscles
0.704 0.296 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.704 0.296 0.000
Q60-Q64 Congenital malformations of the urinary system
0.704 0.296 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.704 0.296 0.000
T87 Complications peculiar to reattachment and amputation
0.703 0.297 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.703 0.297 0.000
S70-S79 Injuries to the hip and thigh
0.703 0.297 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.703 0.297 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.703 0.297 0.000
G47.8 Other sleep disorders
0.703 0.297 0.000
W50-W64 Exposure to animate mechanical forces
0.703 0.297 0.000
D60-D64 Aplastic and other anaemias
0.703 0.297 0.000
C91.9 Lymphoid leukaemia, unspecified
0.702 0.298 0.000
C83.0 Small cell (diffuse)
0.701 0.299 0.000
H44 Disorders of globe
0.701 0.299 0.000
Y52 Agents primarily affecting the cardiovascular system
0.701 0.299 0.000
Z89.6 Acquired absence of leg above knee
0.701 0.299 0.000
H52 Disorders of refraction and accommodation
0.700 0.300 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.700 0.300 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.699 0.301 0.000
A08 Viral and other specified intestinal infections
0.698 0.302 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.698 0.302 0.000
C95 Leukaemia of unspecified cell type
0.698 0.302 0.000
C94 Other leukaemias of specified cell type
0.698 0.302 0.000
C93 Monocytic leukaemia
0.698 0.302 0.000
C86 Other specified types of T/NK-cell lymphoma
0.698 0.302 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.698 0.302 0.000
C81 Hodgkin's disease
0.698 0.302 0.000
C91.1 Chronic lymphocytic leukaemia
0.698 0.302 0.000
T81.9 Unspecified complication of procedure
0.696 0.304 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.696 0.304 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.696 0.304 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.696 0.304 0.000
Z93.9 Artificial opening status, unspecified
0.696 0.304 0.000
Z93.8 Other artificial opening status
0.696 0.304 0.000
Z93.5 Cystostomy status
0.696 0.304 0.000
Z93.0 Tracheostomy status
0.696 0.304 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.696 0.304 0.000
M54.9 Dorsalgia, unspecified
0.696 0.304 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.695 0.305 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.694 0.306 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.694 0.306 0.000
M40-M43 Deforming dorsopathies
0.693 0.307 0.000
C92 Myeloid leukaemia
0.693 0.307 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.692 0.308 0.000
I72 Other aneurysm
0.692 0.308 0.000
R27 Other lack of coordination
0.691 0.309 0.000
H55-H59 Other disorders of eye and adnexa
0.691 0.309 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.691 0.309 0.000
Y83.3 Surgical operation with formation of external stoma
0.689 0.311 0.000
Z96.9 Presence of functional implant, unspecified
0.688 0.312 0.000
Z96.5 Presence of tooth-root and mandibular implants
0.688 0.312 0.000
Z96.4 Presence of endocrine implants
0.688 0.312 0.000
Z96.3 Presence of artificial larynx
0.688 0.312 0.000
Z96.2 Presence of otological and audiological implants
0.688 0.312 0.000
I27 Other pulmonary heart diseases
0.688 0.312 0.000
G40.8 Other epilepsy
0.688 0.312 0.000
G40.5 Special epileptic syndromes
0.688 0.312 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.688 0.312 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.688 0.312 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.686 0.314 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.686 0.314 0.000
S90-S99 Injuries to the ankle and foot
0.685 0.315 0.000
D41.4 Bladder
0.685 0.315 0.000
I10-I15 Hypertensive diseases
0.685 0.315 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.684 0.316 0.000
B98.1 Vibrio vulnificus as the cause of diseases classified to other chapters
0.684 0.316 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.684 0.316 0.000
C07 Malignant neoplasm of parotid gland
0.684 0.316 0.000
M14 Arthropathies in other diseases classified elsewhere
0.683 0.317 0.000
M12 Other specific arthropathies
0.683 0.317 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.683 0.317 0.000
M08 Juvenile arthritis
0.683 0.317 0.000
M54.8 Other dorsalgia
0.683 0.317 0.000
M54.6 Pain in thoracic spine
0.683 0.317 0.000
M54.0 Panniculitis affecting regions of neck and back
0.683 0.317 0.000
G47.3 Sleep apnoea
0.681 0.319 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.681 0.319 0.000
H35.8 Other specified retinal disorders
0.680 0.320 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.680 0.320 0.000
Y35-Y36 Legal intervention and operations of war
0.678 0.322 0.000
Y10-Y34 Event of undetermined intent
0.678 0.322 0.000
Y00-Y09 Assault
0.678 0.322 0.000
X85-X99 Assault
0.678 0.322 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.678 0.322 0.000
X50-X57 Overexertion, travel and privation
0.678 0.322 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.678 0.322 0.000
X30-X39 Exposure to forces of nature
0.678 0.322 0.000
X20-X29 Contact with venomous animals and plants
0.678 0.322 0.000
X10-X19 Contact with heat and hot substances
0.678 0.322 0.000
X00-X09 Exposure to smoke, fire and flames
0.678 0.322 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.678 0.322 0.000
W75-W84 Other accidental threats to breathing
0.678 0.322 0.000
W65-W74 Accidental drowning and submersion
0.678 0.322 0.000
V98-V99 Other and unspecified transport accidents
0.678 0.322 0.000
V95-V97 Air and space transport accidents
0.678 0.322 0.000
V90-V94 Water transport accidents
0.678 0.322 0.000
V70-V79 Bus occupant injured in transport accident
0.678 0.322 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.678 0.322 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.678 0.322 0.000
V40-V49 Car occupant injured in transport accident
0.678 0.322 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.678 0.322 0.000
V01-V09 Pedestrian injured in transport accident
0.678 0.322 0.000
K83.1 Obstruction of bile duct
0.678 0.322 0.000
D47.1 Chronic myeloproliferative disease
0.677 0.322 0.000
T86.8 Failure and rejection of other transplanted organs and tissues
0.677 0.323 0.000
G70 Myasthenia gravis and other myoneural disorders
0.676 0.324 0.000
T86.1 Kidney transplant failure and rejection
0.676 0.324 0.000
Z22 Carrier of infectious disease
0.676 0.324 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.675 0.325 0.000
R76 Other abnormal immunological findings in serum
0.674 0.326 0.000
B15-B19 Viral hepatitis
0.674 0.326 0.000
K91.4 Colostomy and enterostomy malfunction
0.674 0.326 0.000
Z98.2 Presence of cerebrospinal fluid drainage device
0.673 0.327 0.000
C49.2 Connective and soft tissue of lower limb, including hip
0.673 0.327 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.672 0.328 0.000
H31 Other disorders of choroid
0.672 0.328 0.000
H30 Chorioretinal inflammation
0.672 0.328 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.672 0.328 0.000
M06.8 Other specified rheumatoid arthritis
0.672 0.328 0.000
M06.4 Inflammatory polyarthropathy
0.672 0.328 0.000
M06.3 Rheumatoid nodule
0.672 0.328 0.000
M06.2 Rheumatoid bursitis
0.672 0.328 0.000
M06.1 Adult-onset Still's disease
0.672 0.328 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.671 0.328 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.671 0.329 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.670 0.330 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.670 0.330 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.670 0.330 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.669 0.330 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.669 0.330 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.669 0.330 0.000
C67.6 Ureteric orifice
0.669 0.331 0.000
M47 Spondylosis
0.669 0.331 0.000
H73 Other disorders of tympanic membrane
0.669 0.331 0.000
C60-C63 Malignant neoplasms of male genital organs
0.668 0.332 0.000
G47.2 Disorders of the sleep-wake schedule
0.668 0.332 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.667 0.332 0.000
Q80-Q89 Other congenital malformations
0.667 0.332 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.667 0.332 0.000
Q35-Q37 Cleft lip and cleft palate
0.667 0.332 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.667 0.332 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.667 0.332 0.000
I73.8 Other specified peripheral vascular diseases
0.667 0.333 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.667 0.333 0.000
I67 Other cerebrovascular diseases
0.666 0.334 0.000
G44 Other headache syndromes
0.665 0.335 0.000
Z94.9 Transplanted organ and tissue status, unspecified
0.665 0.335 0.000
Z94.6 Bone transplant status
0.665 0.335 0.000
Z94.5 Skin transplant status
0.665 0.335 0.000
Z94.4 Liver transplant status
0.665 0.335 0.000
Z94.3 Heart and lungs transplant status
0.665 0.335 0.000
Z94.2 Lung transplant status
0.665 0.335 0.000
Z94.1 Heart transplant status
0.665 0.335 0.000
M45 Ankylosing spondylitis
0.664 0.336 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.664 0.336 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.664 0.336 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.664 0.336 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.664 0.336 0.000
H69 Other disorders of Eustachian tube
0.664 0.336 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.663 0.337 0.000
S61 Open wound of wrist and hand
0.663 0.337 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.663 0.337 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.663 0.337 0.000
C85.0 Lymphosarcoma
0.663 0.337 0.000
Y40 Systemic antibiotics
0.663 0.337 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.662 0.338 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.662 0.338 0.000
H18 Other disorders of cornea
0.661 0.339 0.000
I22.8 Subsequent myocardial infarction of other sites
0.661 0.339 0.000
V80-V89 Other land transport accidents
0.661 0.339 0.000
H33.3 Retinal breaks without detachment
0.661 0.339 0.000
M54.12 Radiculopathy (Cervical region)
0.661 0.339 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.660 0.339 0.000
M54.50 Low back pain (Multiple sites in spine)
0.660 0.340 0.000
I24 Other acute ischaemic heart diseases
0.660 0.340 0.000
M51.8 Other specified intervertebral disk disorders
0.659 0.341 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.658 0.342 0.000
M46 Other inflammatory spondylopathies
0.657 0.342 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.657 0.343 0.000
C34.1 Upper lobe, bronchus or lung
0.657 0.343 0.000
H71 Cholesteatoma of middle ear
0.656 0.344 0.000
D40.0 Prostate
0.656 0.344 0.000
Y59 Other and unspecified vaccines and biological substances
0.656 0.344 0.000
Y58 Bacterial vaccines
0.656 0.344 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.656 0.344 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.656 0.344 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.656 0.344 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.656 0.344 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.656 0.344 0.000
Y48 Anaesthetics and therapeutic gases
0.656 0.344 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.656 0.344 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.656 0.344 0.000
Q00-Q07 Congenital malformations of the nervous system
0.656 0.344 0.000
R06.0 Dyspnoea
0.656 0.344 0.000
T66-T78 Other and unspecified effects of external causes
0.655 0.345 0.000
R01 Cardiac murmurs and other cardiac sounds
0.655 0.345 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.654 0.346 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.653 0.347 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.653 0.347 0.000
I62 Other nontraumatic intracranial haemorrhage
0.653 0.347 0.000
A41 Other septicaemia
0.653 0.347 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.653 0.347 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.652 0.347 0.000
G20-G26 Extrapyramidal and movement disorders
0.652 0.348 0.000
I08 Multiple valve diseases
0.652 0.348 0.000
S62 Fracture at wrist and hand level
0.651 0.348 0.000
R07.1 Chest pain on breathing
0.651 0.349 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.651 0.349 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.651 0.349 0.000
R20 Disturbances of skin sensation
0.649 0.351 0.000
C32 Malignant neoplasm of larynx
0.649 0.351 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.649 0.351 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.649 0.351 0.000
H17 Corneal scars and opacities
0.649 0.351 0.000
H16 Keratitis
0.649 0.351 0.000
H15 Disorders of sclera
0.649 0.351 0.000
U80.0 Penicillin resistant agent
0.648 0.352 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.648 0.352 0.000
H34 Retinal vascular occlusions
0.648 0.352 0.000
K65-K67 Diseases of peritoneum
0.648 0.352 0.000
Z89.4 Acquired absence of foot and ankle
0.647 0.353 0.000
H33.4 Traction detachment of retina
0.647 0.353 0.000
H33.1 Retinoschisis and retinal cysts
0.647 0.353 0.000
X60-X84 Intentional self-harm
0.647 0.353 0.000
M06.0 Seronegative rheumatoid arthritis
0.647 0.353 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.646 0.353 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.646 0.354 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.645 0.355 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.645 0.355 0.000
M13 Other arthritis
0.645 0.355 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.645 0.355 0.000
C45 Mesothelioma
0.645 0.355 0.000
M05 Seropositive rheumatoid arthritis
0.644 0.356 0.000
S40-S49 Injuries to the shoulder and upper arm
0.644 0.356 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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