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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7521681
log Bayes Factor = 0.0330735
Chromosome 1   position 108,322,535  (GRCh37) Explore rs7521681 on Ensembl!
Variant rs7521681 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10 Insulin-dependent diabetes mellitus
0.187 0.813 0.000
E10.1 With ketoacidosis
0.186 0.814 0.000
E10.5 With peripheral circulatory complications
0.172 0.828 0.000
E10.6 With other specified complications
0.165 0.835 0.000
E10.4 With neurological complications
0.163 0.837 0.000
E10.2 With renal complications
0.155 0.845 0.000
E10.3 With ophthalmic complications
0.154 0.846 0.000
E10.8 With unspecified complications
0.149 0.851 0.000
E10.0 With coma
0.144 0.856 0.000
E10.7 With multiple complications
0.134 0.866 0.000
E10.9 Without complications
0.123 0.877 0.000
E10-E14 Diabetes mellitus
0.066 0.934 0.000
E14 Unspecified diabetes mellitus
0.058 0.942 0.000
E14.3 With ophthalmic complications
0.051 0.949 0.000
E12 Malnutrition-related diabetes mellitus
0.048 0.952 0.000
E14.6 With other specified complications
0.047 0.953 0.000
E13 Other specified diabetes mellitus
0.046 0.954 0.000
E14.5 With peripheral circulatory complications
0.045 0.955 0.000
E14.4 With neurological complications
0.044 0.956 0.000
E14.8 With unspecified complications
0.042 0.958 0.000
E14.7 With multiple complications
0.042 0.958 0.000
E14.2 Withrenal complications
0.042 0.958 0.000
E14.1 With ketoacidosis
0.042 0.958 0.000
E14.0 With coma
0.042 0.958 0.000
D73.0 Hyposplenism
0.000 0.960 0.040
E12.9 Without complications
0.034 0.965 0.000
E12.8 With unspecified complications
0.034 0.965 0.000
E12.7 With multiple complications
0.034 0.965 0.000
E12.6 With other specified complications
0.034 0.965 0.000
E12.5 With peripheral circulatory complications
0.034 0.965 0.000
E12.4 With neurological complications
0.034 0.965 0.000
E12.3 With ophthalmic complications
0.034 0.965 0.000
E12.2 With renal complications
0.034 0.965 0.000
E12.1 With ketoacidosis
0.034 0.965 0.000
E12.0 With coma
0.034 0.965 0.000
E13.8 With unspecified complications
0.033 0.967 0.000
E13.7 With multiple complications
0.033 0.967 0.000
E13.6 With other specified complications
0.033 0.967 0.000
E13.5 With peripheral circulatory complications
0.033 0.967 0.000
E13.4 With neurological complications
0.033 0.967 0.000
E13.3 With ophthalmic complications
0.033 0.967 0.000
E13.2 With renal complications
0.033 0.967 0.000
E13.1 With ketoacidosis
0.033 0.967 0.000
E13.0 With coma
0.033 0.967 0.000
E13.9 Without complications
0.031 0.969 0.000
D73 Diseases of spleen
0.000 0.970 0.030
D73.5 Infarction of spleen
0.000 0.973 0.027
D73.8 Other diseases of spleen
0.000 0.977 0.022
E14.9 Without complications
0.022 0.978 0.000
D73.9 Disease of spleen, unspecified
0.000 0.979 0.021
D73.4 Cyst of spleen
0.000 0.979 0.021
D73.3 Abscess of spleen
0.000 0.979 0.021
D73.2 Chronic congestive splenomegaly
0.000 0.979 0.021
D73.1 Hypersplenism
0.000 0.979 0.021
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.019 0.981 0.000
E21.0 Primary hyperparathyroidism
0.018 0.982 0.000
E20-E35 Disorders of other endocrine glands
0.018 0.982 0.000
E21.3 Hyperparathyroidism, unspecified
0.017 0.983 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.016 0.984 0.000
E27 Other disorders of adrenal gland
0.015 0.985 0.000
E27.1 Primary adrenocortical insufficiency
0.015 0.985 0.000
E20 Hypoparathyroidism
0.014 0.985 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.014 0.986 0.000
E26 Hyperaldosteronism
0.014 0.986 0.000
E34 Other endocrine disorders
0.014 0.986 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.013 0.986 0.000
E21.4 Other specified disorders of parathyroid gland
0.013 0.986 0.000
E21.2 Other hyperparathyroidism
0.013 0.986 0.000
E50-E64 Other nutritional deficiencies
0.013 0.987 0.000
E27.8 Other specified disorders of adrenal gland
0.013 0.987 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.013 0.987 0.000
E32 Diseases of thymus
0.013 0.987 0.000
E31 Polyglandular dysfunction
0.013 0.987 0.000
E30 Disorders of puberty, not elsewhere classified
0.013 0.987 0.000
E25 Adrenogenital disorders
0.013 0.987 0.000
E20.9 Hypoparathyroidism, unspecified
0.012 0.988 0.000
E29 Testicular dysfunction
0.012 0.988 0.000
E34.8 Other specified endocrine disorders
0.012 0.988 0.000
E24 Cushing's syndrome
0.012 0.988 0.000
H65.3 Chronic mucoid otitis media
0.000 0.988 0.012
H65.9 Nonsuppurative otitis media, unspecified
0.000 0.989 0.011
E28 Ovarian dysfunction
0.011 0.989 0.000
E26.9 Hyperaldosteronism, unspecified
0.011 0.989 0.000
E61 Deficiency of other nutrient elements
0.011 0.989 0.000
E26.0 Primary hyperaldosteronism
0.011 0.989 0.000
E27.5 Adrenomedullary hyperfunction
0.011 0.989 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.011 0.989 0.000
E27.0 Other adrenocortical overactivity
0.011 0.989 0.000
E22 Hyperfunction of pituitary gland
0.011 0.989 0.000
E54 Ascorbic acid deficiency
0.011 0.989 0.000
E40-E46 Malnutrition
0.011 0.989 0.000
E20.8 Other hypoparathyroidism
0.010 0.989 0.000
E20.1 Pseudohypoparathyroidism
0.010 0.989 0.000
E20.0 Idiopathic hypoparathyroidism
0.010 0.989 0.000
E23 Hypofunction and other disorders of pituitary gland
0.010 0.989 0.000
E26.8 Other hyperaldosteronism
0.010 0.990 0.000
E26.1 Secondary hyperaldosteronism
0.010 0.990 0.000
E34.0 Carcinoid syndrome
0.010 0.990 0.000
E34.5 Androgen resistance syndrome
0.010 0.990 0.000
E34.4 Constitutional tall stature
0.010 0.990 0.000
E34.3 Short stature, not elsewhere classified
0.010 0.990 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.010 0.990 0.000
E34.1 Other hypersecretion of intestinal hormones
0.010 0.990 0.000
E56 Other vitamin deficiencies
0.010 0.990 0.000
H65 Nonsuppurative otitis media
0.000 0.990 0.010
E51 Thiamine deficiency
0.010 0.990 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.010 0.990 0.000
E61.1 Iron deficiency
0.010 0.990 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.010 0.990 0.000
E63 Other nutritional deficiencies
0.010 0.990 0.000
E50 Vitamin A deficiency
0.010 0.990 0.000
E60 Dietary zinc deficiency
0.010 0.990 0.000
E59 Dietary selenium deficiency
0.010 0.990 0.000
E58 Dietary calcium deficiency
0.010 0.990 0.000
E52 Niacin deficiency [pellagra]
0.010 0.990 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.009 0.990 0.000
E25.9 Adrenogenital disorder, unspecified
0.009 0.990 0.000
E25.8 Other adrenogenital disorders
0.009 0.990 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.009 0.990 0.000
E27.2 Addisonian crisis
0.009 0.990 0.000
E30.9 Disorder of puberty, unspecified
0.009 0.990 0.000
E30.8 Other disorders of puberty
0.009 0.990 0.000
E30.1 Precocious puberty
0.009 0.990 0.000
E30.0 Delayed puberty
0.009 0.990 0.000
E31.9 Polyglandular dysfunction, unspecified
0.009 0.990 0.000
E31.8 Other polyglandular dysfunction
0.009 0.990 0.000
E31.1 Polyglandular hyperfunction
0.009 0.990 0.000
E31.0 Autoimmune polyglandular failure
0.009 0.990 0.000
E32.9 Disease of thymus, unspecified
0.009 0.990 0.000
E32.8 Other diseases of thymus
0.009 0.990 0.000
E32.1 Abscess of thymus
0.009 0.990 0.000
E32.0 Persistent hyperplasia of thymus
0.009 0.990 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.009 0.990 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.009 0.990 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.009 0.990 0.000
E53 Deficiency of other B group vitamins
0.009 0.991 0.000
E34.9 Endocrine disorder, unspecified
0.009 0.991 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.009 0.991 0.000
E29.9 Testicular dysfunction, unspecified
0.009 0.991 0.000
E29.8 Other testicular dysfunction
0.009 0.991 0.000
E29.0 Testicular hyperfunction
0.009 0.991 0.000
S22.40 Multiple fractures of ribs (closed)
0.000 0.991 0.009
E24.8 Other Cushing's syndrome
0.009 0.991 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.009 0.991 0.000
E24.3 Ectopic ACTH syndrome
0.009 0.991 0.000
E24.2 Drug-induced Cushing's syndrome
0.009 0.991 0.000
E24.1 Nelson's syndrome
0.009 0.991 0.000
E24.0 Pituitary-dependent Cushing's disease
0.008 0.991 0.000
E24.9 Cushing's syndrome, unspecified
0.008 0.991 0.000
E29.1 Testicular hypofunction
0.008 0.991 0.000
E28.9 Ovarian dysfunction, unspecified
0.008 0.992 0.000
E28.8 Other ovarian dysfunction
0.008 0.992 0.000
E28.1 Androgen excess
0.008 0.992 0.000
E28.0 Oestrogen excess
0.008 0.992 0.000
E27.9 Disorder of adrenal gland, unspecified
0.008 0.992 0.000
E61.9 Deficiency of nutrient element, unspecified
0.008 0.992 0.000
E61.8 Deficiency of other specified nutrient elements
0.008 0.992 0.000
E61.7 Deficiency of multiple nutrient elements
0.008 0.992 0.000
E61.6 Vanadium deficiency
0.008 0.992 0.000
E61.5 Molybdenum deficiency
0.008 0.992 0.000
E61.4 Chromium deficiency
0.008 0.992 0.000
E61.3 Manganese deficiency
0.008 0.992 0.000
E61.2 Magnesium deficiency
0.008 0.992 0.000
E61.0 Copper deficiency
0.008 0.992 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.008 0.992 0.000
E22.8 Other hyperfunction of pituitary gland
0.008 0.992 0.000
E23.7 Disorder of pituitary gland, unspecified
0.008 0.992 0.000
H65.4 Other chronic nonsuppurative otitis media
0.000 0.992 0.008
E56.1 Deficiency of vitamin K
0.008 0.992 0.000
E53.9 Vitamin B deficiency, unspecified
0.008 0.992 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.008 0.992 0.000
E45 Retarded development following protein-energy malnutrition
0.008 0.992 0.000
E43 Unspecified severe protein-energy malnutrition
0.008 0.992 0.000
E42 Marasmic kwashiorkor
0.008 0.992 0.000
E41 Nutritional marasmus
0.008 0.992 0.000
E40 Kwashiorkor
0.008 0.992 0.000
E28.3 Primary ovarian failure
0.008 0.992 0.000
E55 Vitamin D deficiency
0.008 0.992 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.008 0.992 0.000
E23.1 Drug-induced hypopituitarism
0.008 0.992 0.000
E28.2 Polycystic ovarian syndrome
0.008 0.992 0.000
E51.2 Wernicke's encephalopathy
0.007 0.992 0.000
E56.9 Vitamin deficiency, unspecified
0.007 0.992 0.000
E56.8 Deficiency of other vitamins
0.007 0.992 0.000
E56.0 Deficiency of vitamin E
0.007 0.992 0.000
H65.1 Other acute nonsuppurative otitis media
0.000 0.992 0.007
E51.9 Thiamine deficiency, unspecified
0.007 0.993 0.000
E51.8 Other manifestations of thiamine deficiency
0.007 0.993 0.000
E51.1 Beriberi
0.007 0.993 0.000
E15 Nondiabetic hypoglycaemic coma
0.007 0.993 0.000
E50.9 Vitamin A deficiency, unspecified
0.007 0.993 0.000
E50.8 Other manifestations of vitamin A deficiency
0.007 0.993 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.007 0.993 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.007 0.993 0.000
E50.5 Vitamin A deficiency with night blindness
0.007 0.993 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.007 0.993 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.007 0.993 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.007 0.993 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.007 0.993 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.007 0.993 0.000
E63.9 Nutritional deficiency, unspecified
0.007 0.993 0.000
E63.8 Other specified nutritional deficiencies
0.007 0.993 0.000
E63.1 Imbalance of constituents of food intake
0.007 0.993 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.007 0.993 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.007 0.993 0.000
E64.8 Sequelae of other nutritional deficiencies
0.007 0.993 0.000
E64.3 Sequelae of rickets
0.007 0.993 0.000
E64.2 Sequelae of vitamin C deficiency
0.007 0.993 0.000
E64.1 Sequelae of vitamin A deficiency
0.007 0.993 0.000
E64.0 Sequelae of protein-energy malnutrition
0.007 0.993 0.000
E23.2 Diabetes insipidus
0.007 0.993 0.000
E46 Unspecified protein-energy malnutrition
0.007 0.993 0.000
E23.0 Hypopituitarism
0.007 0.993 0.000
E53.1 Pyridoxine deficiency
0.007 0.993 0.000
E53.0 Riboflavin deficiency
0.007 0.993 0.000
H65.2 Chronic serous otitis media
0.000 0.993 0.007
E22.0 Acromegaly and pituitary gigantism
0.007 0.993 0.000
H65.0 Acute serous otitis media
0.000 0.993 0.007
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.993 0.007
E23.6 Other disorders of pituitary gland
0.006 0.993 0.000
E11 Non-insulin-dependent diabetes mellitus
0.006 0.994 0.000
E44.1 Mild protein-energy malnutrition
0.006 0.994 0.000
E44.0 Moderate protein-energy malnutrition
0.006 0.994 0.000
E55.0 Rickets, active
0.006 0.994 0.000
E22.1 Hyperprolactinaemia
0.005 0.994 0.000
I20.0 Unstable angina
0.006 0.994 0.000
E65-E68 Obesity and other hyperalimentation
0.006 0.994 0.000
D72 Other disorders of white blood cells
0.000 0.994 0.006
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.000 0.994 0.006
Z01.8 Other specified special examinations
0.000 0.994 0.006
E16 Other disorders of pancreatic internal secretion
0.005 0.995 0.000
E11.8 With unspecified complications
0.005 0.995 0.000
E11.2 With renal complications
0.005 0.995 0.000
D74 Methaemoglobinaemia
0.000 0.995 0.005
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.000 0.995 0.005
D71 Functional disorders of polymorphonuclear neutrophils
0.000 0.995 0.005
E11.7 With multiple complications
0.005 0.995 0.000
E53.8 Deficiency of other specified B group vitamins
0.005 0.995 0.000
F03 Unspecified dementia
0.000 0.995 0.005
D76.3 Other histiocytosis syndromes
0.000 0.995 0.005
D72.8 Other specified disorders of white blood cells
0.000 0.995 0.005
S22.4 Multiple fractures of ribs
0.000 0.995 0.005
R12 Heartburn
0.004 0.996 0.000
D72.1 Eosinophilia
0.000 0.996 0.004
E11.4 With neurological complications
0.004 0.996 0.000
Z63.0 Problems in relationship with spouse or partner
0.004 0.996 0.000
E67 Other hyperalimentation
0.004 0.996 0.000
E68 Sequelae of hyperalimentation
0.004 0.996 0.000
E11.3 With ophthalmic complications
0.004 0.996 0.000
D72.9 Disorder of white blood cells, unspecified
0.000 0.996 0.004
D72.0 Genetic anomalies of leukocytes
0.000 0.996 0.004
D76.2 Haemophagocytic syndrome, infection-associated
0.000 0.996 0.004
D76.1 Haemophagocytic lymphohistiocytosis
0.000 0.996 0.004
D76.0 Langerhans' cell histiocytosis, not elsewhere classified
0.000 0.996 0.004
E11.0 With coma
0.004 0.996 0.000
M06.3 Rheumatoid nodule
0.004 0.996 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.004 0.996 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.004 0.996 0.000
E16.4 Abnormal secretion of gastrin
0.004 0.996 0.000
E16.3 Increased secretion of glucagon
0.004 0.996 0.000
E16.1 Other hypoglycaemia
0.004 0.996 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.004 0.996 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.004 0.996 0.000
E11.6 With other specified complications
0.004 0.996 0.000
M06.34 Rheumatoid nodule (Hand)
0.004 0.996 0.000
E11.1 With ketoacidosis
0.004 0.996 0.000
D74.9 Methaemoglobinaemia, unspecified
0.000 0.996 0.004
D74.8 Other methaemoglobinaemias
0.000 0.996 0.004
D74.0 Congenital methaemoglobinaemia
0.000 0.996 0.004
E55.9 Vitamin D deficiency, unspecified
0.004 0.996 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.004 0.996 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.000 0.996 0.004
R03.1 Nonspecific low blood-pressure reading
0.004 0.996 0.000
M06 Other rheumatoid arthritis
0.004 0.996 0.000
S52.80 Fracture of other parts of forearm (closed)
0.004 0.996 0.000
S22.41 Multiple fractures of ribs (open)
0.000 0.996 0.003
K14.9 Disease of tongue, unspecified
0.003 0.996 0.000
H66.9 Otitis media, unspecified
0.000 0.997 0.003
E65 Localised adiposity
0.003 0.997 0.000
E67.8 Other specified hyperalimentation
0.003 0.997 0.000
E67.3 Hypervitaminosis D
0.003 0.997 0.000
E67.2 Megavitamin-B6 syndrome
0.003 0.997 0.000
E67.1 Hypercarotenaemia
0.003 0.997 0.000
E67.0 Hypervitaminosis A
0.003 0.997 0.000
I35.0 Aortic (valve) stenosis
0.003 0.997 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.003 0.997 0.000
M06.38 Rheumatoid nodule (Other)
0.003 0.997 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.003 0.997 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.003 0.997 0.000
M06.33 Rheumatoid nodule (Forearm)
0.003 0.997 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.003 0.997 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.003 0.997 0.000
M31.6 Other giant cell arteritis
0.003 0.997 0.000
M06.9 Rheumatoid arthritis, unspecified
0.003 0.997 0.000
N75.1 Abscess of Bartholin's gland
0.003 0.997 0.000
Z63.7 Other stressful life events affecting family and household
0.003 0.997 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.003 0.997 0.000
T18.1 Foreign body in oesophagus
0.003 0.997 0.000
M06.8 Other specified rheumatoid arthritis
0.003 0.997 0.000
Z63 Other problems related to primary support group, including family circumstances
0.003 0.997 0.000
K22.4 Dyskinesia of oesophagus
0.003 0.997 0.000
M06.0 Seronegative rheumatoid arthritis
0.003 0.997 0.000
Z63.5 Disruption of family by separation and divorce
0.003 0.997 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.003 0.997 0.000
M06.2 Rheumatoid bursitis
0.003 0.997 0.000
M06.1 Adult-onset Still's disease
0.003 0.997 0.000
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.003 0.997 0.000
D70 Agranulocytosis
0.000 0.997 0.003
G95.2 Cord compression, unspecified
0.003 0.997 0.000
M05-M14 Inflammatory polyarthropathies
0.003 0.997 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.003 0.997 0.000
M05 Seropositive rheumatoid arthritis
0.003 0.997 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.003 0.997 0.000
M12 Other specific arthropathies
0.003 0.997 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.003 0.997 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.003 0.997 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.003 0.997 0.000
M10 Gout
0.003 0.997 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.003 0.997 0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.003 0.997 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.003 0.997 0.000
R61.9 Hyperhidrosis, unspecified
0.003 0.997 0.000
H66 Suppurative and unspecified otitis media
0.000 0.997 0.003
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.003 0.997 0.000
D13.1 Stomach
0.003 0.997 0.000
F40.2 Specific (isolated) phobias
0.003 0.997 0.000
K76.8 Other specified diseases of liver
0.003 0.997 0.000
M31.3 Wegener's granulomatosis
0.003 0.997 0.000
M31 Other necrotising vasculopathies
0.003 0.997 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.003 0.997 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.003 0.997 0.000
M07 Psoriatic and enteropathic arthropathies
0.003 0.997 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.003 0.997 0.000
M12.2 Villonodular synovitis (pigmented)
0.002 0.997 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.003 0.997 0.000
B00.5 Herpesviral ocular disease
0.003 0.997 0.000
E11.5 With peripheral circulatory complications
0.002 0.997 0.000
M06.4 Inflammatory polyarthropathy
0.002 0.997 0.000
M12.3 Palindromic rheumatism
0.002 0.997 0.000
Z63.9 Problem related to primary support group, unspecified
0.002 0.997 0.000
Z63.3 Absence of family member
0.002 0.997 0.000
Z63.2 Inadequate family support
0.002 0.997 0.000
Z63.1 Problems in relationship with parents and in-laws
0.002 0.997 0.000
M06.88 Other specified rheumatoid arthritis (Other)
0.002 0.997 0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.002 0.997 0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.002 0.997 0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.002 0.997 0.000
M06.84 Other specified rheumatoid arthritis (Hand)
0.002 0.997 0.000
M06.83 Other specified rheumatoid arthritis (Forearm)
0.002 0.997 0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.002 0.997 0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.002 0.997 0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.002 0.997 0.000
M10.9 Gout, unspecified
0.003 0.997 0.000
Z63.6 Dependent relative needing care at home
0.002 0.997 0.000
N90.7 Vulvar cyst
0.000 0.997 0.003
E00-E07 Disorders of thyroid gland
0.003 0.997 0.000
H65-H75 Diseases of middle ear and mastoid
0.000 0.997 0.002
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.002 0.998 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.002 0.998 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.002 0.998 0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.002 0.998 0.000
M06.04 Seronegative rheumatoid arthritis (Hand)
0.002 0.998 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.002 0.998 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.002 0.998 0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.002 0.998 0.000
D13.4 Liver
0.002 0.998 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.002 0.998 0.000
M12.24 Villonodular synovitis (pigmented) (Hand)
0.002 0.998 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.002 0.998 0.000
M07.3 Other psoriatic arthropathies
0.002 0.998 0.000
M10.0 Idiopathic gout
0.002 0.998 0.000
M14 Arthropathies in other diseases classified elsewhere
0.002 0.998 0.000
M06.19 Adult-onset Still's disease (Site unspecified)
0.002 0.998 0.000
M06.18 Adult-onset Still's disease (Other)
0.002 0.998 0.000
M06.17 Adult-onset Still's disease (Ankle and foot)
0.002 0.998 0.000
M06.16 Adult-onset Still's disease (Lower leg)
0.002 0.998 0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.002 0.998 0.000
M06.14 Adult-onset Still's disease (Hand)
0.002 0.998 0.000
M06.13 Adult-onset Still's disease (Forearm)
0.002 0.998 0.000
M06.12 Adult-onset Still's disease (Upper arm)
0.002 0.998 0.000
M06.11 Adult-onset Still's disease (Shoulder region)
0.002 0.998 0.000
M06.10 Adult-onset Still's disease (Multiple sites)
0.002 0.998 0.000
M06.29 Rheumatoid bursitis (Site unspecified)
0.002 0.998 0.000
M06.28 Rheumatoid bursitis (Other)
0.002 0.998 0.000
M06.27 Rheumatoid bursitis (Ankle and foot)
0.002 0.998 0.000
M06.26 Rheumatoid bursitis (Lower leg)
0.002 0.998 0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.002 0.998 0.000
M06.24 Rheumatoid bursitis (Hand)
0.002 0.998 0.000
M06.23 Rheumatoid bursitis (Forearm)
0.002 0.998 0.000
M06.22 Rheumatoid bursitis (Upper arm)
0.002 0.998 0.000
M06.21 Rheumatoid bursitis (Shoulder region)
0.002 0.998 0.000
M06.20 Rheumatoid bursitis (Multiple sites)
0.002 0.998 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.002 0.998 0.000
M25.46 Effusion of joint (Lower leg)
0.000 0.998 0.002
Z63.8 Other specified problems related to primary support group
0.002 0.998 0.000
M12.30 Palindromic rheumatism (Multiple sites)
0.002 0.998 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.002 0.998 0.000
M08 Juvenile arthritis
0.002 0.998 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.002 0.998 0.000
N90.6 Hypertrophy of vulva
0.000 0.998 0.002
T17.2 Foreign body in pharynx
0.002 0.998 0.000
T18 Foreign body in alimentary tract
0.002 0.998 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.002 0.998 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.002 0.998 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.002 0.998 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.002 0.998 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.002 0.998 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.002 0.998 0.000
M05.8 Other seropositive rheumatoid arthritis
0.002 0.998 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.002 0.998 0.000
M05.2 Rheumatoid vasculitis
0.002 0.998 0.000
M05.1 Rheumatoid lung disease
0.002 0.998 0.000
M05.0 Felty's syndrome
0.002 0.998 0.000
M10.92 Gout, unspecified (Upper arm)
0.002 0.998 0.000
M12.8 Other specific arthropathies, not elsewhere classified
0.002 0.998 0.000
M12.5 Traumatic arthropathy
0.002 0.998 0.000
M12.4 Intermittent hydrarthrosis
0.002 0.998 0.000
M12.1 Kaschin-Beck disease
0.002 0.998 0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.002 0.998 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.002 0.998 0.000
M10.90 Gout, unspecified (Multiple sites)
0.002 0.998 0.000
L29.0 Pruritus ani
0.000 0.998 0.002
M10.94 Gout, unspecified (Hand)
0.002 0.998 0.000
M10.4 Other secondary gout
0.002 0.998 0.000
M10.3 Gout due to impairment of renal function
0.002 0.998 0.000
M10.2 Drug-induced gout
0.002 0.998 0.000
M10.1 Lead-induced gout
0.002 0.998 0.000
B00.4 Herpesviral encephalitis
0.002 0.998 0.000
E16.2 Hypoglycaemia, unspecified
0.002 0.998 0.000
H66.2 Chronic atticoantral suppurative otitis media
0.000 0.998 0.002
H66.1 Chronic tubotympanic suppurative otitis media
0.000 0.998 0.002
H66.0 Acute suppurative otitis media
0.000 0.998 0.002
H73.8 Other specified disorders of tympanic membrane
0.000 0.998 0.002
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.002 0.998 0.000
I12.9 Hypertensive renal disease without renal failure
0.002 0.998 0.000
I12.0 Hypertensive renal disease with renal failure
0.002 0.998 0.000
R25.8 Other and unspecified abnormal involuntary movements
0.000 0.998 0.002
T17 Foreign body in respiratory tract
0.002 0.998 0.000
H73 Other disorders of tympanic membrane
0.000 0.998 0.002
D13.9 Ill-defined sites within the digestive system
0.002 0.998 0.000
M31.9 Necrotising vasculopathy, unspecified
0.002 0.998 0.000
M31.8 Other specified necrotising vasculopathies
0.002 0.998 0.000
M31.7 Microscopic polyangiitis
0.002 0.998 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.002 0.998 0.000
M31.2 Lethal midline granuloma
0.002 0.998 0.000
M31.1 Thrombotic microangiopathy
0.002 0.998 0.000
M31.0 Hypersensitivity angiitis
0.002 0.998 0.000
T18.0 Foreign body in mouth
0.002 0.998 0.000
M10.07 Idiopathic gout (Ankle and foot)
0.002 0.998 0.000
E05.8 Other thyrotoxicosis
0.002 0.998 0.000
M07.6 Other enteropathic arthropathies
0.002 0.998 0.000
M07.5 Arthropathy in ulcerative colitis
0.002 0.998 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.002 0.998 0.000
M07.2 Psoriatic spondylitis
0.002 0.998 0.000
M07.1 Arthritis mutilans
0.002 0.998 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.002 0.998 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.002 0.998 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.002 0.998 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.002 0.998 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.002 0.998 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.002 0.998 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.002 0.998 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.002 0.998 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.002 0.998 0.000
M12.29 Villonodular synovitis (pigmented) (Site unspecified)
0.002 0.998 0.000
M12.28 Villonodular synovitis (pigmented) (Other)
0.002 0.998 0.000
M12.27 Villonodular synovitis (pigmented) (Ankle and foot)
0.002 0.998 0.000
M12.26 Villonodular synovitis (pigmented) (Lower leg)
0.002 0.998 0.000
M12.25 Villonodular synovitis (pigmented) (Pelvic region and thigh)
0.002 0.998 0.000
M12.23 Villonodular synovitis (pigmented) (Forearm)
0.002 0.998 0.000
M12.22 Villonodular synovitis (pigmented) (Upper arm)
0.002 0.998 0.000
M12.21 Villonodular synovitis (pigmented) (Shoulder region)
0.002 0.998 0.000
M12.20 Villonodular synovitis (pigmented) (Multiple sites)
0.002 0.998 0.000
D13.2 Duodenum
0.002 0.998 0.000
M12.39 Palindromic rheumatism (Site unspecified)
0.002 0.998 0.000
M12.38 Palindromic rheumatism (Other)
0.002 0.998 0.000
M12.37 Palindromic rheumatism (Ankle and foot)
0.002 0.998 0.000
M12.36 Palindromic rheumatism (Lower leg)
0.002 0.998 0.000
M12.35 Palindromic rheumatism (Pelvic region and thigh)
0.002 0.998 0.000
M12.34 Palindromic rheumatism (Hand)
0.002 0.998 0.000
M12.33 Palindromic rheumatism (Forearm)
0.002 0.998 0.000
M12.32 Palindromic rheumatism (Upper arm)
0.002 0.998 0.000
M12.31 Palindromic rheumatism (Shoulder region)
0.002 0.998 0.000
M11 Other crystal arthropathies
0.002 0.998 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.002 0.998 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.002 0.998 0.000
M10.98 Gout, unspecified (Other)
0.002 0.998 0.000
M10.95 Gout, unspecified (Pelvic region and thigh)
0.002 0.998 0.000
M10.91 Gout, unspecified (Shoulder region)
0.002 0.998 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.002 0.998 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.002 0.998 0.000
E00 Congenital iodine-deficiency syndrome
0.002 0.998 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.002 0.998 0.000
T17.8 Foreign body in other and multiple parts of respiratory tract
0.002 0.998 0.000
T17.5 Foreign body in bronchus
0.002 0.998 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.002 0.998 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.000 0.998 0.002
H68 Eustachian salpingitis and obstruction
0.000 0.998 0.002
H67 Otitis media in diseases classified elsewhere
0.000 0.998 0.002
M10.93 Gout, unspecified (Forearm)
0.002 0.998 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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