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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75312808
log Bayes Factor = 17.1131
Chromosome 15   position 47,918,724  (GRCh37) Explore rs75312808 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
1.000 0.000 0.000
M50-M54 Other dorsopathies
1.000 0.000 0.000
S00-S09 Injuries to the head
1.000 0.000 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.999 0.001 0.000
M54 Dorsalgia
0.999 0.001 0.000
M05-M14 Inflammatory polyarthropathies
0.999 0.001 0.000
M06 Other rheumatoid arthritis
0.997 0.003 0.000
S01 Open wound of head
0.997 0.003 0.000
I20-I25 Ischaemic heart diseases
0.997 0.003 0.000
I74 Arterial embolism and thrombosis
0.994 0.006 0.000
M06.9 Rheumatoid arthritis, unspecified
0.992 0.008 0.000
M54.5 Low back pain
0.991 0.009 0.000
Chapter XX External causes of morbidity and mortality
0.991 0.009 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.989 0.011 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.985 0.015 0.000
M54.3 Sciatica
0.983 0.017 0.000
M50 Cervical disk disorders
0.982 0.018 0.000
S01.8 Open wound of other parts of head
0.980 0.020 0.000
I25 Chronic ischaemic heart disease
0.977 0.023 0.000
I20 Angina pectoris
0.974 0.026 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.974 0.026 0.000
Chapter V Mental and behavioural disorders
0.969 0.031 0.000
S90-S99 Injuries to the ankle and foot
0.964 0.036 0.000
I73 Other peripheral vascular diseases
0.957 0.043 0.000
O00-O08 Pregnancy with abortive outcome
0.956 0.044 0.000
I74.5 Embolism and thrombosis of iliac artery
0.950 0.050 0.000
S06 Intracranial injury
0.949 0.051 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.945 0.055 0.000
M54.56 Low back pain (Lumbar region)
0.944 0.056 0.000
I20.9 Angina pectoris, unspecified
0.942 0.058 0.000
M54.59 Low back pain (Site unspecified)
0.941 0.059 0.000
I77 Other disorders of arteries and arterioles
0.938 0.062 0.000
M54.36 Sciatica (Lumbar region)
0.931 0.069 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.928 0.072 0.000
S92 Fracture of foot, except ankle
0.923 0.077 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.922 0.078 0.000
Chapter XXI Factors influencing health status and contact with health services
0.920 0.080 0.000
F60-F69 Disorders of adult personality and behaviour
0.920 0.080 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.919 0.081 0.000
M06.3 Rheumatoid nodule
0.918 0.082 0.000
I30-I52 Other forms of heart disease
0.917 0.083 0.000
Z72 Problems related to lifestyle
0.917 0.083 0.000
Z72.0 Tobacco use
0.913 0.087 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.911 0.089 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.907 0.093 0.000
M50.0 Cervical disk disorder with myelopathy
0.904 0.096 0.000
I73.9 Peripheral vascular disease, unspecified
0.901 0.099 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.900 0.100 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.899 0.101 0.000
T66-T78 Other and unspecified effects of external causes
0.896 0.104 0.000
M50.1 Cervical disk disorder with radiculopathy
0.896 0.104 0.000
M54.39 Sciatica (Site unspecified)
0.889 0.111 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.886 0.114 0.000
I50 Heart failure
0.885 0.115 0.000
F60 Specific personality disorders
0.885 0.115 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.882 0.118 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.881 0.119 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.879 0.121 0.000
I51 Complications and ill-defined descriptions of heart disease
0.877 0.123 0.000
I77.1 Stricture of artery
0.877 0.123 0.000
W20-W49 Exposure to inanimate mechanical forces
0.877 0.123 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.872 0.128 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.870 0.130 0.000
Z75 Problems related to medical facilities and other health care
0.869 0.131 0.000
V10-V19 Pedal cyclist injured in transport accident
0.867 0.133 0.000
I25.2 Old myocardial infarction
0.866 0.134 0.000
S92.3 Fracture of metatarsal bone
0.866 0.134 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.863 0.137 0.000
M45-M49 Spondylopathies
0.862 0.138 0.000
S02 Fracture of skull and facial bones
0.862 0.138 0.000
M60-M63 Disorders of muscles
0.860 0.140 0.000
I50.0 Congestive heart failure
0.859 0.141 0.000
I25.5 Ischaemic cardiomyopathy
0.858 0.142 0.000
I71 Aortic aneurysm and dissection
0.857 0.143 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.856 0.144 0.000
M80-M85 Disorders of bone density and structure
0.856 0.144 0.000
W00-W19 Falls
0.856 0.144 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.851 0.149 0.000
M70-M79 Other soft tissue disorders
0.846 0.154 0.000
S01.3 Open wound of ear
0.845 0.155 0.000
S05 Injury of eye and orbit
0.844 0.156 0.000
Y52 Agents primarily affecting the cardiovascular system
0.842 0.158 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.841 0.159 0.000
I20.8 Other forms of angina pectoris
0.839 0.161 0.000
I78 Diseases of capillaries
0.837 0.163 0.000
Z76 Persons encountering health services in other circumstances
0.837 0.163 0.000
O02 Other abnormal products of conception
0.836 0.164 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.836 0.164 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.834 0.166 0.000
I72 Other aneurysm
0.833 0.167 0.000
S01.2 Open wound of nose
0.832 0.168 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.832 0.168 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.831 0.169 0.000
O03 Spontaneous abortion
0.831 0.169 0.000
O00 Ectopic pregnancy
0.831 0.169 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.830 0.170 0.000
I46 Cardiac arrest
0.828 0.172 0.000
S01.9 Open wound of head, part unspecified
0.828 0.172 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.827 0.173 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.827 0.173 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.826 0.174 0.000
Y43 Primarily systemic agents
0.826 0.174 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.826 0.174 0.000
S92.30 Fracture of metatarsal bone (closed)
0.825 0.175 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.825 0.175 0.000
M50.2 Other cervical disk displacement
0.824 0.176 0.000
M86-M90 Other osteopathies
0.824 0.176 0.000
M91-M94 Chondropathies
0.823 0.177 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.823 0.177 0.000
I51.8 Other ill-defined heart diseases
0.822 0.178 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.818 0.182 0.000
I74.8 Embolism and thrombosis of other arteries
0.817 0.183 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.815 0.185 0.000
M05 Seropositive rheumatoid arthritis
0.814 0.186 0.000
M14 Arthropathies in other diseases classified elsewhere
0.814 0.186 0.000
I05-I09 Chronic rheumatic heart diseases
0.814 0.186 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.814 0.186 0.000
S10-S19 Injuries to the neck
0.814 0.186 0.000
O42 Premature rupture of membranes
0.812 0.188 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.810 0.190 0.000
F60.9 Personality disorder, unspecified
0.809 0.191 0.000
M54.9 Dorsalgia, unspecified
0.809 0.191 0.000
M54.37 Sciatica (Lumbosacral region)
0.808 0.192 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.806 0.194 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.803 0.197 0.000
F60.3 Emotionally unstable personality disorder
0.801 0.199 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.800 0.200 0.000
T42.4 Benzodiazepines
0.799 0.201 0.000
I46.0 Cardiac arrest with successful resuscitation
0.797 0.203 0.000
M47 Spondylosis
0.796 0.204 0.000
F41 Other anxiety disorders
0.796 0.204 0.000
S06.3 Focal brain injury
0.796 0.204 0.000
S01.0 Open wound of scalp
0.793 0.207 0.000
W19 Unspecified fall
0.793 0.207 0.000
F40 Phobic anxiety disorders
0.792 0.208 0.000
I51.9 Heart disease, unspecified
0.791 0.209 0.000
R21 Rash and other nonspecific skin eruption
0.791 0.209 0.000
M65-M68 Disorders of synovium and tendon
0.790 0.210 0.000
M06.34 Rheumatoid nodule (Hand)
0.790 0.210 0.000
I33 Acute and subacute endocarditis
0.787 0.213 0.000
I20.1 Angina pectoris with documented spasm
0.784 0.216 0.000
S06.5 Traumatic subdural haemorrhage
0.782 0.218 0.000
Z75.4 Unavailability and inaccessibility of other helping agencies
0.782 0.218 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.781 0.219 0.000
I45 Other conduction disorders
0.781 0.219 0.000
Z75.1 Person awaiting admission to adequate facility elsewhere
0.781 0.219 0.000
I73.0 Raynaud's syndrome
0.780 0.220 0.000
I23 Certain current complications following acute myocardial infarction
0.779 0.221 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.778 0.222 0.000
I95 Hypotension
0.778 0.222 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.776 0.224 0.000
M81 Osteoporosis without pathological fracture
0.776 0.224 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.775 0.225 0.000
S01.5 Open wound of lip and oral cavity
0.775 0.225 0.000
F99-F99 Unspecified mental disorder
0.774 0.226 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.774 0.226 0.000
M47.9 Spondylosis, unspecified
0.773 0.227 0.000
M10 Gout
0.773 0.227 0.000
I70 Atherosclerosis
0.773 0.227 0.000
Chapter XI Diseases of the digestive system
0.772 0.228 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.768 0.232 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.767 0.232 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.767 0.233 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.767 0.233 0.000
W44 Foreign body entering into or through eye or natural orifice
0.767 0.233 0.000
M50.9 Cervical disk disorder, unspecified
0.764 0.236 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.764 0.236 0.000
O36 Maternal care for other known or suspected foetal problems
0.764 0.236 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.763 0.237 0.000
O80-O84 Delivery
0.762 0.238 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.762 0.238 0.000
M06.4 Inflammatory polyarthropathy
0.761 0.239 0.000
V80-V89 Other land transport accidents
0.761 0.239 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.761 0.239 0.000
W50-W64 Exposure to animate mechanical forces
0.760 0.240 0.000
S40-S49 Injuries to the shoulder and upper arm
0.760 0.240 0.000
S01.7 Multiple open wounds of head
0.759 0.241 0.000
T68 Hypothermia
0.758 0.242 0.000
T78 Adverse effects, not elsewhere classified
0.758 0.242 0.000
Z76.9 Persons encountering health services in unspecified circumstances
0.757 0.243 0.000
S06.0 Concussion
0.757 0.243 0.000
S06.8 Other intracranial injuries
0.755 0.245 0.000
Y43.3 Other antineoplastic drugs
0.755 0.245 0.000
K86 Other diseases of pancreas
0.754 0.246 0.000
T00-T07 Injuries involving multiple body regions
0.753 0.247 0.000
M54.57 Low back pain (Lumbosacral region)
0.751 0.249 0.000
Chapter VII Diseases of the eye and adnexa
0.751 0.249 0.000
X41.9 Unspecified place
0.751 0.249 0.000
O02.1 Missed abortion
0.750 0.250 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.750 0.250 0.000
I95.2 Hypotension due to drugs
0.749 0.251 0.000
S99 Other and unspecified injuries of ankle and foot
0.748 0.252 0.000
T43.2 Other and unspecified antidepressants
0.747 0.253 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.747 0.253 0.000
M06.0 Seronegative rheumatoid arthritis
0.746 0.254 0.000
M62 Other disorders of muscle
0.744 0.256 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.743 0.257 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.742 0.258 0.000
F41.9 Anxiety disorder, unspecified
0.741 0.259 0.000
M79.8 Other specified soft tissue disorders
0.740 0.260 0.000
S91 Open wound of ankle and foot
0.739 0.261 0.000
O04 Medical abortion
0.738 0.262 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.738 0.262 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.737 0.263 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.737 0.263 0.000
W22 Striking against or struck by other objects
0.736 0.264 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.736 0.264 0.000
M79.6 Pain in limb
0.735 0.265 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.734 0.266 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.733 0.267 0.000
X50-X57 Overexertion, travel and privation
0.732 0.268 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.732 0.268 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.731 0.269 0.000
S70-S79 Injuries to the hip and thigh
0.730 0.270 0.000
I08 Multiple valve diseases
0.729 0.271 0.000
F43 Reaction to severe stress, and adjustment disorders
0.728 0.272 0.000
I24 Other acute ischaemic heart diseases
0.727 0.273 0.000
I50.1 Left ventricular failure
0.726 0.274 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.725 0.274 0.000
I73.8 Other specified peripheral vascular diseases
0.725 0.275 0.000
I10-I15 Hypertensive diseases
0.725 0.275 0.000
R05 Cough
0.725 0.275 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.721 0.278 0.000
Y48 Anaesthetics and therapeutic gases
0.721 0.279 0.000
I77.6 Arteritis, unspecified
0.720 0.280 0.000
M81.9 Osteoporosis, unspecified
0.718 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.717 0.283 0.000
M71 Other bursopathies
0.717 0.283 0.000
S08 Traumatic amputation of part of head
0.717 0.283 0.000
S07 Crushing injury of head
0.717 0.283 0.000
S04 Injury of cranial nerves
0.717 0.283 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.717 0.283 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.717 0.283 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.717 0.283 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.717 0.283 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.717 0.283 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.717 0.283 0.000
T36 Poisoning by systemic antibiotics
0.717 0.283 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.716 0.284 0.000
M54.8 Other dorsalgia
0.716 0.284 0.000
M54.0 Panniculitis affecting regions of neck and back
0.716 0.284 0.000
M12 Other specific arthropathies
0.716 0.284 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.716 0.284 0.000
M08 Juvenile arthritis
0.716 0.284 0.000
Z63 Other problems related to primary support group, including family circumstances
0.715 0.285 0.000
O03.9 Complete or unspecified, without complication
0.715 0.285 0.000
V18.0 Driver injured in nontraffic accident
0.715 0.285 0.000
M06.8 Other specified rheumatoid arthritis
0.715 0.285 0.000
M06.2 Rheumatoid bursitis
0.715 0.285 0.000
M06.1 Adult-onset Still's disease
0.715 0.285 0.000
S05.1 Contusion of eyeball and orbital tissues
0.715 0.285 0.000
M54.55 Low back pain (Thoracolumbar region)
0.715 0.285 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.712 0.288 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.712 0.288 0.000
M79.67 Pain in limb (Ankle and foot)
0.712 0.288 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.711 0.289 0.000
I72.3 Aneurysm of iliac artery
0.711 0.289 0.000
S92.1 Fracture of talus
0.711 0.289 0.000
M54.54 Low back pain-Thoracic
0.710 0.289 0.000
M54.53 Low back pain-Cervicothoracic
0.710 0.289 0.000
M54.52 Low back pain-Cervical
0.710 0.289 0.000
M54.51 Low back pain-Occipit-atl-axl
0.710 0.289 0.000
Y35-Y36 Legal intervention and operations of war
0.710 0.290 0.000
Y10-Y34 Event of undetermined intent
0.710 0.290 0.000
X85-X99 Assault
0.710 0.290 0.000
X30-X39 Exposure to forces of nature
0.710 0.290 0.000
X10-X19 Contact with heat and hot substances
0.710 0.290 0.000
X00-X09 Exposure to smoke, fire and flames
0.710 0.290 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.710 0.290 0.000
W75-W84 Other accidental threats to breathing
0.710 0.290 0.000
W65-W74 Accidental drowning and submersion
0.710 0.290 0.000
V98-V99 Other and unspecified transport accidents
0.710 0.290 0.000
V95-V97 Air and space transport accidents
0.710 0.290 0.000
V90-V94 Water transport accidents
0.710 0.290 0.000
V70-V79 Bus occupant injured in transport accident
0.710 0.290 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.710 0.290 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.710 0.290 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.710 0.290 0.000
V01-V09 Pedestrian injured in transport accident
0.710 0.290 0.000
Y00-Y09 Assault
0.710 0.290 0.000
T43.9 Psychotropic drug, unspecified
0.709 0.291 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.709 0.291 0.000
T43.6 Psychostimulants with abuse potential
0.709 0.291 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.709 0.291 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.709 0.291 0.000
I25.3 Aneurysm of heart
0.709 0.291 0.000
S92.2 Fracture of other tarsal bone(s)
0.708 0.292 0.000
F40.2 Specific (isolated) phobias
0.707 0.293 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.707 0.293 0.000
S01.4 Open wound of cheek and temporomandibular area
0.707 0.293 0.000
H43-H45 Disorders of vitreous body and globe
0.707 0.293 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.706 0.294 0.000
Q50-Q56 Congenital malformations of genital organs
0.706 0.294 0.000
S92.0 Fracture of calcaneus
0.705 0.295 0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.705 0.295 0.000
M54.35 Sciatica (Thoracolumbar region)
0.705 0.295 0.000
M54.34 Sciatica-Thoracic
0.705 0.295 0.000
M54.33 Sciatica-Cervicothoracic
0.705 0.295 0.000
M54.32 Sciatica-Cervical
0.705 0.295 0.000
M54.31 Sciatica-Occipit-atl-axl
0.705 0.295 0.000
M54.30 Sciatica (Multiple sites in spine)
0.705 0.295 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.705 0.295 0.000
M50.8 Other cervical disk disorders
0.704 0.295 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.704 0.296 0.000
M53 Other dorsopathies, not elsewhere classified
0.703 0.297 0.000
I08.0 Disorders of both mitral and aortic valves
0.703 0.297 0.000
M51 Other intervertebral disk disorders
0.702 0.298 0.000
Z57 Occupational exposure to risk-factors
0.702 0.298 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.701 0.299 0.000
I25.6 Silent myocardial ischaemia
0.700 0.300 0.000
I25.4 Coronary artery aneurysm
0.700 0.300 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.700 0.300 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.700 0.300 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.698 0.302 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.698 0.302 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.698 0.302 0.000
T42.3 Barbiturates
0.698 0.302 0.000
T42.2 Succinimides and oxazolidinediones
0.698 0.302 0.000
T42.1 Iminostilbenes
0.698 0.302 0.000
T42.0 Hydantoin derivatives
0.698 0.302 0.000
O00.1 Tubal pregnancy
0.697 0.303 0.000
S02.2 Fracture of nasal bones
0.697 0.303 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.696 0.304 0.000
Q00-Q07 Congenital malformations of the nervous system
0.696 0.304 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.694 0.306 0.000
F70-F79 Mental retardation
0.694 0.306 0.000
V20-V29 Motorcycle rider injured in transport accident
0.694 0.306 0.000
K86.1 Other chronic pancreatitis
0.693 0.307 0.000
I33.0 Acute and subacute infective endocarditis
0.693 0.307 0.000
T38.1 Thyroid hormones and substitutes
0.693 0.307 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.693 0.307 0.000
M13 Other arthritis
0.692 0.308 0.000
T79-T79 Certain early complications of trauma
0.692 0.308 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.692 0.308 0.000
W19.4 Street and highway
0.691 0.309 0.000
S98 Traumatic amputation of ankle and foot
0.691 0.309 0.000
S97 Crushing injury of ankle and foot
0.691 0.309 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.691 0.309 0.000
S95 Injury of blood vessels at ankle and foot level
0.691 0.309 0.000
S94 Injury of nerves at ankle and foot level
0.691 0.309 0.000
M54.4 Lumbago with sciatica
0.690 0.310 0.000
V40-V49 Car occupant injured in transport accident
0.690 0.310 0.000
M67 Other disorders of synovium and tendon
0.690 0.310 0.000
I37 Pulmonary valve disorders
0.690 0.310 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.689 0.311 0.000
X20-X29 Contact with venomous animals and plants
0.689 0.311 0.000
W20 Struck by thrown, projected or falling object
0.689 0.311 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.689 0.311 0.000
S90 Superficial injury of ankle and foot
0.688 0.312 0.000
W44.0 Home
0.688 0.312 0.000
S02.6 Fracture of mandible
0.688 0.312 0.000
K85 Acute pancreatitis
0.687 0.313 0.000
O85-O92 Complications predominantly related to the puerperium
0.687 0.313 0.000
Z72.2 Drug use
0.686 0.314 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.686 0.314 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.686 0.314 0.000
O41 Other disorders of amniotic fluid and membranes
0.686 0.314 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.686 0.314 0.000
S06.30 Focal brain injury (without open intracranial wound)
0.686 0.314 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.686 0.314 0.000
M94 Other disorders of cartilage
0.685 0.314 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.685 0.315 0.000
O07 Failed attempted abortion
0.685 0.315 0.000
O06 Unspecified abortion
0.685 0.315 0.000
O05 Other abortion
0.685 0.315 0.000
O01 Hydatidiform mole
0.685 0.315 0.000
I78.8 Other diseases of capillaries
0.685 0.315 0.000
H43 Disorders of vitreous body
0.684 0.316 0.000
K82 Other diseases of gallbladder
0.683 0.317 0.000
I71.0 Dissection of aorta [any part]
0.682 0.317 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.682 0.318 0.000
M14.6 Neuropathic arthropathy
0.682 0.318 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.681 0.319 0.000
S06.9 Intracranial injury, unspecified
0.680 0.320 0.000
S06.7 Intracranial injury with prolonged coma
0.680 0.320 0.000
S06.4 Epidural haemorrhage
0.680 0.320 0.000
S06.1 Traumatic cerebral oedema
0.680 0.320 0.000
M86 Osteomyelitis
0.679 0.321 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.679 0.321 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.679 0.321 0.000
W18 Other fall on same level
0.679 0.321 0.000
R94 Abnormal results of function studies
0.677 0.323 0.000
S92.5 Fracture of other toe
0.677 0.323 0.000
S02.7 Multiple fractures involving skull and facial bones
0.677 0.323 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.676 0.324 0.000
M84 Disorders of continuity of bone
0.676 0.324 0.000
K08 Other disorders of teeth and supporting structures
0.675 0.325 0.000
I97.2 Postmastectomy lymphoedema syndrome
0.673 0.327 0.000
O00.9 Ectopic pregnancy, unspecified
0.673 0.327 0.000
I77.5 Necrosis of artery
0.672 0.327 0.000
I77.4 Coeliac artery compression syndrome
0.672 0.327 0.000
I77.3 Arterial fibromuscular dysplasia
0.672 0.327 0.000
I77.2 Rupture of artery
0.672 0.327 0.000
I77.0 Arteriovenous fistula, acquired
0.672 0.327 0.000
X60-X84 Intentional self-harm
0.672 0.328 0.000
S01.1 Open wound of eyelid and periocular area
0.671 0.329 0.000
O40 Polyhydramnios
0.670 0.330 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.670 0.330 0.000
R23 Other skin changes
0.670 0.330 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.669 0.331 0.000
T90 Sequelae of injuries of head
0.669 0.331 0.000
F50 Eating disorders
0.668 0.332 0.000
K86.8 Other specified diseases of pancreas
0.667 0.333 0.000
S60-S69 Injuries to the wrist and hand
0.667 0.333 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.666 0.334 0.000
M50.3 Other cervical disk degeneration
0.665 0.334 0.000
I78.1 Naevus, nonneoplastic
0.665 0.335 0.000
O42.9 Premature rupture of membranes, unspecified
0.665 0.335 0.000
R06 Abnormalities of breathing
0.664 0.336 0.000
S06.2 Diffuse brain injury
0.664 0.336 0.000
S02.3 Fracture of orbital floor
0.663 0.337 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.663 0.337 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.663 0.337 0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)
0.662 0.337 0.000
F42 Obsessive-compulsive disorder
0.662 0.338 0.000
S92.9 Fracture of foot, unspecified
0.661 0.338 0.000
S92.7 Multiple fractures of foot
0.661 0.338 0.000
S92.4 Fracture of great toe
0.661 0.338 0.000
M62.8 Other specified disorders of muscle
0.661 0.339 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.661 0.339 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.661 0.339 0.000
I36 Nonrheumatic tricuspid valve disorders
0.659 0.341 0.000
F68 Other disorders of adult personality and behaviour
0.659 0.341 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.659 0.341 0.000
F65 Disorders of sexual preference
0.659 0.341 0.000
F64 Gender identity disorders
0.659 0.341 0.000
F63 Habit and impulse disorders
0.659 0.341 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.659 0.341 0.000
F69 Unspecified disorder of adult personality and behaviour
0.659 0.341 0.000
F61 Mixed and other personality disorders
0.659 0.341 0.000
Y59 Other and unspecified vaccines and biological substances
0.659 0.341 0.000
Y58 Bacterial vaccines
0.659 0.341 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.659 0.341 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.659 0.341 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.659 0.341 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.659 0.341 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.659 0.341 0.000
T23 Burn and corrosion of wrist and hand
0.659 0.341 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.658 0.342 0.000
M06.38 Rheumatoid nodule (Other)
0.658 0.342 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.658 0.342 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.658 0.342 0.000
M06.33 Rheumatoid nodule (Forearm)
0.658 0.342 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.658 0.342 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.658 0.342 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.658 0.342 0.000
I52 Other heart disorders in diseases classified elsewhere
0.658 0.342 0.000
I48 Atrial fibrillation and flutter
0.658 0.342 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.658 0.342 0.000
I41 Myocarditis in diseases classified elsewhere
0.658 0.342 0.000
I40 Acute myocarditis
0.658 0.342 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.658 0.342 0.000
I32 Pericarditis in diseases classified elsewhere
0.658 0.342 0.000
Z72.9 Problem related to lifestyle, unspecified
0.657 0.343 0.000
Z72.8 Other problems related to lifestyle
0.657 0.343 0.000
Z72.6 Gambling and betting
0.657 0.343 0.000
Z72.5 High-risk sexual behaviour
0.657 0.343 0.000
Z72.4 Inappropriate diet and eating habits
0.657 0.343 0.000
Z72.3 Lack of physical exercise
0.657 0.343 0.000
T18 Foreign body in alimentary tract
0.657 0.343 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.657 0.343 0.000
I12 Hypertensive renal disease
0.656 0.344 0.000
W19.1 Residential institution
0.656 0.344 0.000
S02.0 Fracture of vault of skull
0.654 0.345 0.000
Z76.3 Healthy person accompanying sick person
0.654 0.346 0.000
T51 Toxic effect of alcohol
0.654 0.346 0.000
F48 Other neurotic disorders
0.653 0.347 0.000
F44 Dissociative [conversion] disorders
0.653 0.347 0.000
Y57 Other and unspecified drugs and medicaments
0.653 0.347 0.000
Chapter XXII Codes for special purposes
0.652 0.348 0.000
Z59 Problems related to housing and economic circumstances
0.651 0.349 0.000
H10-H13 Disorders of conjunctiva
0.649 0.350 0.000
H43.8 Other disorders of vitreous body
0.649 0.351 0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.649 0.351 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.648 0.351 0.000
T21 Burn and corrosion of trunk
0.648 0.352 0.000
O03.4 Incomplete, without complication
0.648 0.352 0.000
M54.6 Pain in thoracic spine
0.648 0.352 0.000
M60 Myositis
0.648 0.352 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.648 0.352 0.000
M54.50 Low back pain (Multiple sites in spine)
0.647 0.353 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.645 0.355 0.000
K86.9 Disease of pancreas, unspecified
0.644 0.356 0.000
M40-M43 Deforming dorsopathies
0.644 0.356 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.643 0.357 0.000
I45.8 Other specified conduction disorders
0.642 0.358 0.000
T75 Effects of other external causes
0.642 0.358 0.000
T74 Maltreatment syndromes
0.642 0.358 0.000
T73 Effects of other deprivation
0.642 0.358 0.000
T70 Effects of air pressure and water pressure
0.642 0.358 0.000
T69 Other effects of reduced temperature
0.642 0.358 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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