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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75404215
log Bayes Factor = 14.5116
Chromosome 7   position 15,472,901  (GRCh37) Explore rs75404215 on Ensembl!
Variant rs75404215 is part of Cluster X0059

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.997 0.003 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.996 0.004 0.000
M20-M25 Other joint disorders
0.994 0.006 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.987 0.013 0.000
E00-E07 Disorders of thyroid gland
0.985 0.015 0.000
Z51 Other medical care
0.985 0.015 0.000
C79 Secondary malignant neoplasm of other sites
0.983 0.017 0.000
Chapter XIV Diseases of the genitourinary system
0.978 0.022 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.977 0.023 0.000
Z51.5 Palliative care
0.976 0.024 0.000
C78.7 Secondary malignant neoplasm of liver
0.972 0.028 0.000
M20 Acquired deformities of fingers and toes
0.971 0.029 0.000
Z45 Adjustment and management of implanted device
0.971 0.029 0.000
Chapter VI Diseases of the nervous system
0.971 0.029 0.000
M25 Other joint disorders, not elsewhere classified
0.967 0.033 0.000
Z96 Presence of other functional implants
0.964 0.036 0.000
Z50 Care involving use of rehabilitation procedures
0.964 0.036 0.000
N17-N19 Renal failure
0.962 0.038 0.000
C34 Malignant neoplasm of bronchus and lung
0.960 0.040 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.957 0.043 0.000
E10-E14 Diabetes mellitus
0.957 0.043 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.954 0.046 0.000
E03 Other hypothyroidism
0.947 0.053 0.000
M05-M14 Inflammatory polyarthropathies
0.946 0.054 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.946 0.054 0.000
Chapter I Certain infectious and parasitic diseases
0.941 0.059 0.000
G90-G99 Other disorders of the nervous system
0.941 0.059 0.000
C34.9 Bronchus or lung, unspecified
0.935 0.065 0.000
D00-D09 In situ neoplasms
0.932 0.068 0.000
Z96.1 Presence of intraocular lens
0.931 0.069 0.000
N17 Acute renal failure
0.930 0.070 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.923 0.077 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.921 0.079 0.000
E03.9 Hypothyroidism, unspecified
0.920 0.080 0.000
N30-N39 Other diseases of urinary system
0.920 0.080 0.000
M20.1 Hallux valgus (acquired)
0.915 0.085 0.000
Z87 Personal history of other diseases and conditions
0.915 0.085 0.000
R04 Haemorrhage from respiratory passages
0.913 0.087 0.000
R07 Pain in throat and chest
0.912 0.088 0.000
M25.5 Pain in joint
0.911 0.089 0.000
Z94 Transplanted organ and tissue status
0.911 0.089 0.000
N17.9 Acute renal failure, unspecified
0.907 0.093 0.000
Z50.1 Other physical therapy
0.898 0.102 0.000
Z45.2 Adjustment and management of vascular access device
0.897 0.103 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.893 0.107 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.893 0.107 0.000
G93 Other disorders of brain
0.887 0.113 0.000
C15-C26 Malignant neoplasms of digestive organs
0.885 0.115 0.000
C78.0 Secondary malignant neoplasm of lung
0.883 0.117 0.000
E20-E35 Disorders of other endocrine glands
0.882 0.118 0.000
M31 Other necrotising vasculopathies
0.879 0.121 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.878 0.122 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.878 0.122 0.000
E14 Unspecified diabetes mellitus
0.878 0.122 0.000
M20.4 Other hammer toe(s) (acquired)
0.877 0.123 0.000
N32 Other disorders of bladder
0.877 0.123 0.000
Z42 Follow-up care involving plastic surgery
0.873 0.127 0.000
Z97 Presence of other devices
0.870 0.130 0.000
Z49 Care involving dialysis
0.868 0.132 0.000
N10-N16 Renal tubulo-interstitial diseases
0.868 0.132 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.868 0.132 0.000
M10 Gout
0.867 0.133 0.000
Chapter XX External causes of morbidity and mortality
0.866 0.134 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.865 0.135 0.000
Z51.1 Chemotherapy session for neoplasm
0.863 0.137 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.858 0.142 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.855 0.145 0.000
Chapter VIII Diseases of the ear and mastoid process
0.855 0.145 0.000
C78.2 Secondary malignant neoplasm of pleura
0.853 0.146 0.000
C64-C68 Malignant neoplasms of urinary tract
0.853 0.147 0.000
M65-M68 Disorders of synovium and tendon
0.851 0.149 0.000
R04.2 Haemoptysis
0.847 0.153 0.000
N32.8 Other specified disorders of bladder
0.846 0.154 0.000
B95-B98 Bacterial, viral and other infectious agents
0.844 0.156 0.000
E10 Insulin-dependent diabetes mellitus
0.844 0.156 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.843 0.157 0.000
M13 Other arthritis
0.842 0.158 0.000
Z96.8 Presence of other specified functional implants
0.840 0.160 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.839 0.161 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.838 0.162 0.000
Z96.0 Presence of urogenital implants
0.838 0.162 0.000
Z48 Other surgical follow-up care
0.836 0.164 0.000
R20 Disturbances of skin sensation
0.835 0.165 0.000
N18 Chronic renal failure
0.833 0.167 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.833 0.167 0.000
M20.2 Hallux rigidus
0.831 0.169 0.000
Chapter VII Diseases of the eye and adnexa
0.829 0.171 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.828 0.172 0.000
M25.57 Pain in joint (Ankle and foot)
0.826 0.174 0.000
G20-G26 Extrapyramidal and movement disorders
0.826 0.174 0.000
R07.2 Precordial pain
0.825 0.175 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.825 0.175 0.000
E06 Thyroiditis
0.824 0.176 0.000
Chapter V Mental and behavioural disorders
0.822 0.178 0.000
R04.0 Epistaxis
0.821 0.179 0.000
E04 Other non-toxic goitre
0.819 0.181 0.000
D05 Carcinoma in situ of breast
0.819 0.181 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.818 0.182 0.000
Z41 Procedures for purposes other than remedying health state
0.817 0.183 0.000
Z45.1 Adjustment and management of infusion pump
0.815 0.185 0.000
M80-M85 Disorders of bone density and structure
0.813 0.187 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.812 0.188 0.000
M10.9 Gout, unspecified
0.810 0.190 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.808 0.192 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.804 0.196 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.803 0.197 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.802 0.198 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.801 0.199 0.000
Z94.0 Kidney transplant status
0.801 0.199 0.000
B35-B49 Mycoses
0.801 0.199 0.000
Z50.5 Speech therapy
0.799 0.201 0.000
G93.3 Postviral fatigue syndrome
0.798 0.202 0.000
M31.6 Other giant cell arteritis
0.797 0.203 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.795 0.205 0.000
Z83 Family history of other specific disorders
0.793 0.207 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.793 0.207 0.000
H30-H36 Disorders of choroid and retina
0.791 0.209 0.000
G30-G32 Other degenerative diseases of the nervous system
0.789 0.211 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.789 0.211 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.787 0.212 0.000
Z51.8 Other specified medical care
0.786 0.214 0.000
M25.4 Effusion of joint
0.784 0.216 0.000
D03 Melanoma in situ
0.782 0.218 0.000
C90.0 Multiple myeloma
0.777 0.223 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.776 0.224 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.774 0.226 0.000
E14.9 Without complications
0.772 0.228 0.000
M10.99 Gout, unspecified (Site unspecified)
0.771 0.229 0.000
R02 Gangrene, not elsewhere classified
0.771 0.229 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.771 0.229 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.769 0.230 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.769 0.231 0.000
G93.6 Cerebral oedema
0.769 0.231 0.000
G70-G73 Diseases of myoneural junction and muscle
0.765 0.235 0.000
Z97.5 Presence of (intra-uterine) contraceptive device
0.765 0.235 0.000
R07.4 Chest pain, unspecified
0.765 0.235 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.764 0.236 0.000
C34.3 Lower lobe, bronchus or lung
0.764 0.236 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.764 0.236 0.000
E10.4 With neurological complications
0.764 0.236 0.000
M45-M49 Spondylopathies
0.761 0.239 0.000
Z51.3 Blood transfusion without reported diagnosis
0.760 0.240 0.000
M25.54 Pain in joint (Hand)
0.760 0.240 0.000
G96 Other disorders of central nervous system
0.759 0.241 0.000
M25.8 Other specified joint disorders
0.758 0.242 0.000
Z52 Donors of organs and tissues
0.758 0.242 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.755 0.245 0.000
M13.9 Arthritis, unspecified
0.755 0.245 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.754 0.246 0.000
Z13 Special screening examination for other diseases and disorders
0.754 0.246 0.000
M65 Synovitis and tenosynovitis
0.754 0.246 0.000
N19 Unspecified renal failure
0.754 0.246 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.753 0.247 0.000
C71 Malignant neoplasm of brain
0.753 0.247 0.000
Z98 Other postsurgical states
0.752 0.248 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.752 0.248 0.000
R06 Abnormalities of breathing
0.751 0.249 0.000
C77.3 Axillary and upper limb lymph nodes
0.751 0.249 0.000
M25.7 Osteophyte
0.750 0.250 0.000
M86-M90 Other osteopathies
0.750 0.250 0.000
C34.0 Main bronchus
0.749 0.251 0.000
C79.2 Secondary malignant neoplasm of skin
0.747 0.253 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.746 0.254 0.000
E14.3 With ophthalmic complications
0.746 0.254 0.000
S60-S69 Injuries to the wrist and hand
0.746 0.254 0.000
R07.3 Other chest pain
0.745 0.255 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.745 0.255 0.000
E05.9 Thyrotoxicosis, unspecified
0.745 0.255 0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities
0.743 0.257 0.000
Z87.1 Personal history of diseases of the digestive system
0.743 0.257 0.000
A30-A49 Other bacterial diseases
0.742 0.258 0.000
N18.0 End-stage renal disease
0.742 0.258 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.742 0.258 0.000
Z94.8 Other transplanted organ and tissue status
0.741 0.259 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.741 0.259 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.739 0.261 0.000
M00-M03 Infectious arthropathies
0.739 0.261 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.738 0.262 0.000
Z49.1 Extracorporeal dialysis
0.735 0.265 0.000
Z42.0 Follow-up care involving plastic surgery of head and neck
0.734 0.266 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.734 0.266 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.733 0.267 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.733 0.267 0.000
Z13.9 Special screening examination, unspecified
0.732 0.268 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.731 0.269 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.730 0.270 0.000
C34.1 Upper lobe, bronchus or lung
0.726 0.274 0.000
E50-E64 Other nutritional deficiencies
0.725 0.274 0.000
R07.0 Pain in throat
0.725 0.275 0.000
N32.1 Vesicointestinal fistula
0.725 0.275 0.000
D04 Carcinoma in situ of skin
0.722 0.278 0.000
Z50.2 Alcohol rehabilitation
0.720 0.280 0.000
Chapter X Diseases of the respiratory system
0.718 0.282 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.718 0.282 0.000
C25 Malignant neoplasm of pancreas
0.718 0.282 0.000
Z90.1 Acquired absence of breast(s)
0.718 0.282 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
Z54 Convalescence
0.717 0.283 0.000
Z44 Fitting and adjustment of external prosthetic device
0.717 0.283 0.000
M91-M94 Chondropathies
0.716 0.284 0.000
M60-M63 Disorders of muscles
0.716 0.284 0.000
N31.8 Other neuromuscular dysfunction of bladder
0.716 0.284 0.000
E40-E46 Malnutrition
0.714 0.285 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.714 0.286 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.714 0.286 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.714 0.286 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.714 0.286 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.714 0.286 0.000
Z94.7 Corneal transplant status
0.714 0.286 0.000
C80 Malignant neoplasm without specification of site
0.714 0.286 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.713 0.287 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.713 0.287 0.000
M34 Systemic sclerosis
0.713 0.287 0.000
M33 Dermatopolymyositis
0.713 0.287 0.000
M32 Systemic lupus erythematosus
0.713 0.287 0.000
M30 Polyarteritis nodosa and related conditions
0.713 0.287 0.000
M21 Other acquired deformities of limbs
0.713 0.287 0.000
C67 Malignant neoplasm of bladder
0.713 0.287 0.000
H34 Retinal vascular occlusions
0.713 0.287 0.000
M20.0 Deformity of finger(s)
0.712 0.288 0.000
Z89 Acquired absence of limb
0.711 0.288 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.711 0.288 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.711 0.289 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.711 0.289 0.000
N18.5 Chronic kidney disease, stage 5
0.711 0.289 0.000
E06.3 Autoimmune thyroiditis
0.709 0.291 0.000
N13 Obstructive and reflux uropathy
0.709 0.291 0.000
D06 Carcinoma in situ of cervix uteri
0.709 0.291 0.000
E11 Non-insulin-dependent diabetes mellitus
0.709 0.291 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.708 0.292 0.000
Z84 Family history of other conditions
0.708 0.292 0.000
Z81 Family history of mental and behavioural disorders
0.708 0.292 0.000
N34 Urethritis and urethral syndrome
0.707 0.293 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.706 0.294 0.000
E00 Congenital iodine-deficiency syndrome
0.706 0.294 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.706 0.294 0.000
Z51.9 Medical care, unspecified
0.706 0.294 0.000
Z51.6 Desensitisation to allergens
0.706 0.294 0.000
C79.6 Secondary malignant neoplasm of ovary
0.705 0.295 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.705 0.295 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.705 0.295 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.705 0.295 0.000
G95 Other diseases of spinal cord
0.705 0.295 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.703 0.296 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.704 0.296 0.000
R26 Abnormalities of gait and mobility
0.703 0.297 0.000
F30-F39 Mood [affective] disorders
0.703 0.297 0.000
M24 Other specific joint derangements
0.703 0.297 0.000
H90-H95 Other disorders of ear
0.703 0.297 0.000
Chapter XXII Codes for special purposes
0.703 0.297 0.000
M07 Psoriatic and enteropathic arthropathies
0.703 0.297 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.702 0.298 0.000
C51-C58 Malignant neoplasms of female genital organs
0.701 0.299 0.000
E13 Other specified diabetes mellitus
0.700 0.300 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.700 0.300 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.700 0.300 0.000
C32 Malignant neoplasm of larynx
0.700 0.300 0.000
C31 Malignant neoplasm of accessory sinuses
0.700 0.300 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.700 0.300 0.000
C37 Malignant neoplasm of thymus
0.700 0.300 0.000
C33 Malignant neoplasm of trachea
0.700 0.300 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.700 0.300 0.000
R06.5 Mouth breathing
0.699 0.301 0.000
M05 Seropositive rheumatoid arthritis
0.699 0.301 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.698 0.302 0.000
X50-X57 Overexertion, travel and privation
0.698 0.302 0.000
C77.9 Lymph node, unspecified
0.697 0.303 0.000
R47-R49 Symptoms and signs involving speech and voice
0.697 0.303 0.000
Z45.9 Adjustment and management of unspecified implanted device
0.696 0.304 0.000
Z45.3 Adjustment and management of implanted hearing device
0.696 0.304 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.696 0.304 0.000
Z49.0 Preparatory care for dialysis
0.694 0.305 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.694 0.306 0.000
M25.9 Joint disorder, unspecified
0.693 0.306 0.000
M25.3 Other instability of joint
0.693 0.306 0.000
M25.2 Flail joint
0.693 0.306 0.000
M25.1 Fistula of joint
0.693 0.306 0.000
M25.0 Haemarthrosis
0.693 0.306 0.000
M50-M54 Other dorsopathies
0.692 0.308 0.000
Z96.9 Presence of functional implant, unspecified
0.691 0.308 0.000
Z96.5 Presence of tooth-root and mandibular implants
0.691 0.308 0.000
Z96.4 Presence of endocrine implants
0.691 0.308 0.000
Z96.3 Presence of artificial larynx
0.691 0.308 0.000
Z96.2 Presence of otological and audiological implants
0.691 0.308 0.000
Z50.6 Orthoptic training
0.691 0.309 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.691 0.309 0.000
Z50.3 Drug rehabilitation
0.691 0.309 0.000
E04.9 Non-toxic goitre, unspecified
0.691 0.309 0.000
G97.8 Other postprocedural disorders of nervous system
0.691 0.309 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.691 0.309 0.000
C16 Malignant neoplasm of stomach
0.690 0.310 0.000
D46 Myelodysplastic syndromes
0.689 0.311 0.000
H10-H13 Disorders of conjunctiva
0.688 0.312 0.000
C34.8 Overlapping lesion of bronchus and lung
0.688 0.312 0.000
C34.2 Middle lobe, bronchus or lung
0.688 0.312 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.688 0.312 0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance
0.687 0.313 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.686 0.314 0.000
E12 Malnutrition-related diabetes mellitus
0.686 0.314 0.000
E28 Ovarian dysfunction
0.686 0.314 0.000
M11 Other crystal arthropathies
0.686 0.314 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.686 0.314 0.000
C91 Lymphoid leukaemia
0.686 0.314 0.000
Z80 Family history of malignant neoplasm
0.684 0.316 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.684 0.316 0.000
S40-S49 Injuries to the shoulder and upper arm
0.683 0.317 0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified
0.682 0.318 0.000
R20.2 Paraesthesia of skin
0.681 0.319 0.000
E21.3 Hyperparathyroidism, unspecified
0.681 0.319 0.000
G20 Parkinson's disease
0.680 0.320 0.000
C77.1 Intrathoracic lymph nodes
0.679 0.321 0.000
E03.8 Other specified hypothyroidism
0.679 0.321 0.000
E03.5 Myxoedema coma
0.679 0.321 0.000
E03.4 Atrophy of thyroid (acquired)
0.679 0.321 0.000
E03.3 Postinfectious hypothyroidism
0.679 0.321 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.679 0.321 0.000
E03.1 Congenital hypothyroidism without goitre
0.679 0.321 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.679 0.321 0.000
C50-C50 Malignant neoplasm of breast
0.679 0.321 0.000
M14 Arthropathies in other diseases classified elsewhere
0.678 0.321 0.000
M12 Other specific arthropathies
0.678 0.321 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.678 0.321 0.000
M08 Juvenile arthritis
0.678 0.321 0.000
C18 Malignant neoplasm of colon
0.678 0.322 0.000
D05.1 Intraductal carcinoma in situ
0.677 0.323 0.000
N40-N51 Diseases of male genital organs
0.676 0.324 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.676 0.324 0.000
J40-J47 Chronic lower respiratory diseases
0.676 0.324 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.675 0.325 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.675 0.325 0.000
B99-B99 Other infectious diseases
0.675 0.325 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.675 0.325 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.675 0.325 0.000
B65-B83 Helminthiases
0.675 0.325 0.000
B50-B64 Protozoal diseases
0.675 0.325 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.675 0.325 0.000
B15-B19 Viral hepatitis
0.675 0.325 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.675 0.325 0.000
A80-A89 Viral infections of the central nervous system
0.675 0.325 0.000
A75-A79 Rickettsioses
0.675 0.325 0.000
A70-A74 Other diseases caused by chlamydiae
0.675 0.325 0.000
A65-A69 Other spirochaetal diseases
0.675 0.325 0.000
A20-A28 Certain zoonotic bacterial diseases
0.675 0.325 0.000
A15-A19 Tuberculosis
0.675 0.325 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.675 0.325 0.000
G90 Disorders of autonomic nervous system
0.675 0.325 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.675 0.325 0.000
G92 Toxic encephalopathy
0.675 0.325 0.000
Y43 Primarily systemic agents
0.674 0.325 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.674 0.326 0.000
H65-H75 Diseases of middle ear and mastoid
0.674 0.326 0.000
Y40 Systemic antibiotics
0.674 0.326 0.000
D03.5 Melanoma in situ of trunk
0.674 0.326 0.000
N00-N08 Glomerular diseases
0.674 0.326 0.000
C77.0 Lymph nodes of head, face and neck
0.673 0.327 0.000
G24 Dystonia
0.672 0.327 0.000
B37 Candidiasis
0.672 0.328 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.671 0.329 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.671 0.329 0.000
N99-N99 Other disorders of the genitourinary system
0.670 0.330 0.000
N35 Urethral stricture
0.670 0.330 0.000
M20.3 Other deformity of hallux (acquired)
0.669 0.331 0.000
D09 Carcinoma in situ of other and unspecified sites
0.669 0.331 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.669 0.331 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.669 0.331 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.669 0.331 0.000
E27 Other disorders of adrenal gland
0.668 0.332 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.667 0.333 0.000
N17.8 Other acute renal failure
0.667 0.333 0.000
N17.2 Acute renal failure with medullary necrosis
0.667 0.333 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.667 0.333 0.000
N17.0 Acute renal failure with tubular necrosis
0.667 0.333 0.000
Z40 Prophylactic surgery
0.667 0.333 0.000
Z99.2 Dependence on renal dialysis
0.666 0.334 0.000
E04.2 Non-toxic multinodular goitre
0.666 0.334 0.000
S70-S79 Injuries to the hip and thigh
0.666 0.334 0.000
C69 Malignant neoplasm of eye and adnexa
0.666 0.334 0.000
E10.9 Without complications
0.666 0.334 0.000
R23 Other skin changes
0.665 0.335 0.000
J47 Bronchiectasis
0.665 0.335 0.000
S90-S99 Injuries to the ankle and foot
0.665 0.335 0.000
M84 Disorders of continuity of bone
0.664 0.336 0.000
V20-V29 Motorcycle rider injured in transport accident
0.663 0.337 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.662 0.338 0.000
C95 Leukaemia of unspecified cell type
0.662 0.338 0.000
C94 Other leukaemias of specified cell type
0.662 0.338 0.000
C93 Monocytic leukaemia
0.662 0.338 0.000
C88 Malignant immunoproliferative diseases
0.662 0.338 0.000
C86 Other specified types of T/NK-cell lymphoma
0.662 0.338 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.662 0.338 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.660 0.340 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.660 0.340 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.660 0.340 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.660 0.340 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.660 0.340 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.660 0.340 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.660 0.340 0.000
N37 Urethral disorders in diseases classified elsewhere
0.659 0.341 0.000
N33 Bladder disorders in diseases classified elsewhere
0.659 0.341 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.659 0.341 0.000
M25.53 Pain in joint (Forearm)
0.659 0.341 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.658 0.342 0.000
G93.9 Disorder of brain, unspecified
0.657 0.342 0.000
C15 Malignant neoplasm of oesophagus
0.657 0.343 0.000
Z45.8 Adjustment and management of other implanted devices
0.657 0.343 0.000
C81 Hodgkin's disease
0.656 0.344 0.000
Z87.6 Personal history of certain conditions arising in the perinatal period
0.656 0.344 0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium
0.656 0.344 0.000
Z96.7 Presence of other bone and tendon implants
0.656 0.344 0.000
R04.9 Haemorrhage from respiratory passages, unspecified
0.655 0.345 0.000
R04.8 Haemorrhage from other sites in respiratory passages
0.655 0.345 0.000
R04.1 Haemorrhage from throat
0.655 0.345 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.654 0.346 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.654 0.346 0.000
Z48.8 Other specified surgical follow-up care
0.654 0.346 0.000
M25.59 Pain in joint (Site unspecified)
0.653 0.347 0.000
M25.58 Pain in joint (Other)
0.653 0.347 0.000
M25.52 Pain in joint (Upper arm)
0.653 0.347 0.000
Q00-Q07 Congenital malformations of the nervous system
0.653 0.347 0.000
Z94.9 Transplanted organ and tissue status, unspecified
0.653 0.347 0.000
Z94.6 Bone transplant status
0.653 0.347 0.000
Z94.5 Skin transplant status
0.653 0.347 0.000
Z94.4 Liver transplant status
0.653 0.347 0.000
Z94.3 Heart and lungs transplant status
0.653 0.347 0.000
Z94.2 Lung transplant status
0.653 0.347 0.000
Z94.1 Heart transplant status
0.653 0.347 0.000
S80-S89 Injuries to the knee and lower leg
0.653 0.347 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.652 0.348 0.000
Z48.9 Surgical follow-up care, unspecified
0.652 0.348 0.000
R01 Cardiac murmurs and other cardiac sounds
0.652 0.348 0.000
Z97.4 Presence of external hearing-aid
0.651 0.349 0.000
N20-N23 Urolithiasis
0.651 0.349 0.000
M25.50 Pain in joint (Multiple sites)
0.651 0.349 0.000
Z97.8 Presence of other specified devices
0.650 0.350 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.650 0.350 0.000
Z88.5 Personal history of allergy to narcotic agent
0.649 0.351 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.649 0.351 0.000
H43-H45 Disorders of vitreous body and globe
0.648 0.352 0.000
G81 Hemiplegia
0.647 0.353 0.000
R07.1 Chest pain on breathing
0.646 0.354 0.000
M25.46 Effusion of joint (Lower leg)
0.646 0.354 0.000
N32.9 Bladder disorder, unspecified
0.644 0.356 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.644 0.356 0.000
R80 Isolated proteinuria
0.643 0.356 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.643 0.357 0.000
D45 Polycythaemia vera
0.643 0.357 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.642 0.357 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.642 0.358 0.000
G83 Other paralytic syndromes
0.642 0.358 0.000
D47.1 Chronic myeloproliferative disease
0.642 0.358 0.000
R09.0 Asphyxia
0.641 0.358 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.641 0.359 0.000
S20-S29 Injuries to the thorax
0.641 0.359 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.641 0.359 0.000
H31 Other disorders of choroid
0.640 0.359 0.000
Z48.0 Attention to surgical dressings and sutures
0.640 0.360 0.000
T33-T35 Frostbite
0.640 0.360 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.640 0.360 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.640 0.360 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.640 0.360 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.640 0.360 0.000
T00-T07 Injuries involving multiple body regions
0.640 0.360 0.000
S10-S19 Injuries to the neck
0.640 0.360 0.000
M13.0 Polyarthritis, unspecified
0.640 0.360 0.000
N36 Other disorders of urethra
0.640 0.360 0.000
G30 Alzheimer's disease
0.637 0.362 0.000
Z83.4 Family history of other endocrine, nutritional and metabolic diseases
0.636 0.364 0.000
G93.8 Other specified disorders of brain
0.636 0.364 0.000
G93.7 Reye's syndrome
0.636 0.364 0.000
G93.5 Compression of brain
0.636 0.364 0.000
G93.4 Encephalopathy, unspecified
0.636 0.364 0.000
G93.2 Benign intracranial hypertension
0.636 0.364 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.636 0.364 0.000
G93.0 Cerebral cysts
0.636 0.364 0.000
Z87.8 Personal history of other specified conditions
0.636 0.364 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.635 0.365 0.000
C21 Malignant neoplasm of anus and anal canal
0.635 0.365 0.000
C17 Malignant neoplasm of small intestine
0.635 0.365 0.000
C23 Malignant neoplasm of gallbladder
0.635 0.365 0.000
Z50.8 Care involving use of rehabilitation procedures
0.634 0.365 0.000
F80-F89 Disorders of psychological development
0.634 0.366 0.000
E07 Other disorders of thyroid
0.633 0.367 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.633 0.367 0.000
E34 Other endocrine disorders
0.633 0.367 0.000
E32 Diseases of thymus
0.633 0.367 0.000
E31 Polyglandular dysfunction
0.633 0.367 0.000
E30 Disorders of puberty, not elsewhere classified
0.633 0.367 0.000
E29 Testicular dysfunction
0.633 0.367 0.000
E26 Hyperaldosteronism
0.633 0.367 0.000
E25 Adrenogenital disorders
0.633 0.367 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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