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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7550711
log Bayes Factor = 14.669
Chromosome 1   position 110,082,886  (GRCh37) Explore rs7550711 on Ensembl!
Variant rs7550711 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
J40-J47 Chronic lower respiratory diseases
0.995 0.005 0.000
I50 Heart failure
0.995 0.005 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.995 0.005 0.000
Chapter XX External causes of morbidity and mortality
0.993 0.007 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.992 0.008 0.000
I26 Pulmonary embolism
0.991 0.009 0.000
E10 Insulin-dependent diabetes mellitus
0.989 0.011 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.989 0.011 0.000
J09-J18 Influenza and pneumonia
0.988 0.012 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.987 0.013 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.987 0.013 0.000
I50.0 Congestive heart failure
0.985 0.015 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.984 0.016 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.983 0.017 0.000
I51 Complications and ill-defined descriptions of heart disease
0.979 0.021 0.000
T81 Complications of procedures, not elsewhere classified
0.976 0.024 0.000
E11 Non-insulin-dependent diabetes mellitus
0.975 0.025 0.000
E10.9 Without complications
0.974 0.026 0.000
J18 Pneumonia, organism unspecified
0.973 0.027 0.000
E14 Unspecified diabetes mellitus
0.972 0.028 0.000
E20-E35 Disorders of other endocrine glands
0.972 0.028 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.970 0.030 0.000
Chapter XIV Diseases of the genitourinary system
0.969 0.031 0.000
J18.9 Pneumonia, unspecified
0.968 0.032 0.000
M45-M49 Spondylopathies
0.967 0.033 0.000
N17-N19 Renal failure
0.967 0.033 0.000
I46 Cardiac arrest
0.962 0.038 0.000
S00-S09 Injuries to the head
0.961 0.039 0.000
J44 Other chronic obstructive pulmonary disease
0.961 0.039 0.000
N17 Acute renal failure
0.957 0.043 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.953 0.047 0.000
N17.9 Acute renal failure, unspecified
0.951 0.049 0.000
I44 Atrioventricular and left bundle-branch block
0.950 0.050 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.949 0.051 0.000
M48 Other spondylopathies
0.947 0.053 0.000
J43 Emphysema
0.946 0.054 0.000
E14.9 Without complications
0.945 0.055 0.000
S01 Open wound of head
0.933 0.067 0.000
M48.0 Spinal stenosis
0.933 0.067 0.000
I51.7 Cardiomegaly
0.928 0.072 0.000
I42 Cardiomyopathy
0.923 0.077 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.922 0.078 0.000
M48.06 Spinal stenosis (Lumbar region)
0.915 0.085 0.000
J43.9 Emphysema, unspecified
0.911 0.089 0.000
E11.5 With peripheral circulatory complications
0.905 0.095 0.000
J95-J99 Other diseases of the respiratory system
0.899 0.101 0.000
J47 Bronchiectasis
0.896 0.104 0.000
N18 Chronic renal failure
0.894 0.106 0.000
I71 Aortic aneurysm and dissection
0.894 0.106 0.000
Y52 Agents primarily affecting the cardiovascular system
0.893 0.107 0.000
I50.1 Left ventricular failure
0.892 0.108 0.000
I46.0 Cardiac arrest with successful resuscitation
0.885 0.115 0.000
I51.9 Heart disease, unspecified
0.878 0.122 0.000
N40-N51 Diseases of male genital organs
0.878 0.122 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.878 0.122 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.876 0.124 0.000
Y44 Agents primarily affecting blood constituents
0.874 0.126 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.873 0.127 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.869 0.131 0.000
T87 Complications peculiar to reattachment and amputation
0.869 0.131 0.000
M86-M90 Other osteopathies
0.868 0.132 0.000
I44.7 Left bundle-branch block, unspecified
0.868 0.132 0.000
N41 Inflammatory diseases of prostate
0.866 0.134 0.000
I46.9 Cardiac arrest, unspecified
0.863 0.136 0.000
J00-J06 Acute upper respiratory infections
0.863 0.137 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.862 0.138 0.000
M05-M14 Inflammatory polyarthropathies
0.859 0.141 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.858 0.142 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.854 0.146 0.000
E10.4 With neurological complications
0.852 0.148 0.000
I42.0 Dilated cardiomyopathy
0.850 0.150 0.000
I38 Endocarditis, valve unspecified
0.849 0.151 0.000
W20-W49 Exposure to inanimate mechanical forces
0.848 0.151 0.000
E11.9 Without complications
0.848 0.152 0.000
N41.1 Chronic prostatitis
0.848 0.152 0.000
E23 Hypofunction and other disorders of pituitary gland
0.846 0.154 0.000
E27 Other disorders of adrenal gland
0.845 0.155 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.843 0.157 0.000
I77 Other disorders of arteries and arterioles
0.843 0.157 0.000
L08 Other local infections of skin and subcutaneous tissue
0.840 0.160 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.839 0.161 0.000
Y40 Systemic antibiotics
0.836 0.164 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.833 0.167 0.000
I74 Arterial embolism and thrombosis
0.832 0.168 0.000
I49 Other cardiac arrhythmias
0.832 0.168 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.830 0.170 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.830 0.170 0.000
S01.9 Open wound of head, part unspecified
0.829 0.171 0.000
T86 Failure and rejection of transplanted organs and tissues
0.828 0.172 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.828 0.172 0.000
Chapter VI Diseases of the nervous system
0.827 0.173 0.000
N00-N08 Glomerular diseases
0.822 0.178 0.000
E10.5 With peripheral circulatory complications
0.821 0.179 0.000
S02 Fracture of skull and facial bones
0.817 0.183 0.000
S01.0 Open wound of scalp
0.815 0.185 0.000
J98 Other respiratory disorders
0.815 0.185 0.000
I44.2 Atrioventricular block, complete
0.812 0.188 0.000
M46 Other inflammatory spondylopathies
0.810 0.190 0.000
I36 Nonrheumatic tricuspid valve disorders
0.805 0.195 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.802 0.198 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.801 0.199 0.000
S80-S89 Injuries to the knee and lower leg
0.800 0.200 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.799 0.201 0.000
N18.9 Chronic renal failure, unspecified
0.799 0.201 0.000
I72 Other aneurysm
0.796 0.203 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.795 0.204 0.000
Chapter XXII Codes for special purposes
0.795 0.205 0.000
E11.2 With renal complications
0.795 0.205 0.000
N40 Hyperplasia of prostate
0.794 0.206 0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.793 0.207 0.000
I31 Other diseases of pericardium
0.793 0.207 0.000
I70 Atherosclerosis
0.792 0.208 0.000
L20-L30 Dermatitis and eczema
0.784 0.216 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.783 0.217 0.000
G90-G99 Other disorders of the nervous system
0.781 0.219 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.781 0.219 0.000
N18.0 End-stage renal disease
0.780 0.220 0.000
M80-M85 Disorders of bone density and structure
0.780 0.220 0.000
E22 Hyperfunction of pituitary gland
0.779 0.221 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.778 0.222 0.000
E11.4 With neurological complications
0.772 0.228 0.000
M48.09 Spinal stenosis (Site unspecified)
0.768 0.232 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.768 0.232 0.000
S01.8 Open wound of other parts of head
0.766 0.234 0.000
E14.3 With ophthalmic complications
0.765 0.234 0.000
J10 Influenza due to identified influenza virus
0.764 0.236 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.763 0.236 0.000
S20-S29 Injuries to the thorax
0.762 0.238 0.000
I45 Other conduction disorders
0.761 0.239 0.000
J42 Unspecified chronic bronchitis
0.760 0.240 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.760 0.240 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.759 0.241 0.000
V20-V29 Motorcycle rider injured in transport accident
0.758 0.242 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.757 0.243 0.000
M45 Ankylosing spondylitis
0.756 0.243 0.000
I51.8 Other ill-defined heart diseases
0.756 0.244 0.000
N19 Unspecified renal failure
0.756 0.244 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.754 0.246 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.753 0.247 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.752 0.248 0.000
E11.6 With other specified complications
0.751 0.249 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.750 0.250 0.000
M20-M25 Other joint disorders
0.749 0.251 0.000
N41.0 Acute prostatitis
0.749 0.251 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.747 0.253 0.000
J14 Pneumonia due to Haemophilus influenzae
0.746 0.254 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.746 0.254 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.745 0.255 0.000
I35 Nonrheumatic aortic valve disorders
0.745 0.255 0.000
L50-L54 Urticaria and erythema
0.744 0.256 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.743 0.256 0.000
T66-T78 Other and unspecified effects of external causes
0.743 0.257 0.000
S50-S59 Injuries to the elbow and forearm
0.742 0.258 0.000
V80-V89 Other land transport accidents
0.742 0.258 0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.741 0.259 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.741 0.259 0.000
S90-S99 Injuries to the ankle and foot
0.741 0.259 0.000
Y45.1 Salicylates
0.740 0.260 0.000
V40-V49 Car occupant injured in transport accident
0.739 0.261 0.000
J98.1 Pulmonary collapse
0.739 0.261 0.000
J00 Acute nasopharyngitis [common cold]
0.736 0.264 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.735 0.265 0.000
M00-M03 Infectious arthropathies
0.734 0.265 0.000
T87.6 Other and unspecified complications of amputation stump
0.734 0.265 0.000
S00 Superficial injury of head
0.734 0.266 0.000
Y44.2 Anticoagulants
0.734 0.266 0.000
Y44.5 Thrombolytic drugs
0.731 0.269 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.731 0.269 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.731 0.269 0.000
M40-M43 Deforming dorsopathies
0.730 0.270 0.000
E23.2 Diabetes insipidus
0.730 0.270 0.000
I10-I15 Hypertensive diseases
0.729 0.271 0.000
E28 Ovarian dysfunction
0.729 0.271 0.000
S70-S79 Injuries to the hip and thigh
0.728 0.272 0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.726 0.274 0.000
Y40.0 Penicillins
0.726 0.274 0.000
S01.1 Open wound of eyelid and periocular area
0.725 0.275 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.723 0.276 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.722 0.278 0.000
I80 Phlebitis and thrombophlebitis
0.722 0.278 0.000
M13 Other arthritis
0.721 0.279 0.000
S01.7 Multiple open wounds of head
0.721 0.279 0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.721 0.279 0.000
T93 Sequelae of injuries of lower limb
0.721 0.279 0.000
T79-T79 Certain early complications of trauma
0.718 0.282 0.000
I60-I69 Cerebrovascular diseases
0.718 0.282 0.000
M86 Osteomyelitis
0.718 0.282 0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.718 0.282 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E13 Other specified diabetes mellitus
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
S10-S19 Injuries to the neck
0.716 0.284 0.000
I44.1 Atrioventricular block, second degree
0.716 0.284 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.715 0.285 0.000
J45 Asthma
0.715 0.285 0.000
S32 Fracture of lumbar spine and pelvis
0.714 0.286 0.000
J41 Simple and mucopurulent chronic bronchitis
0.713 0.286 0.000
I28 Other diseases of pulmonary vessels
0.713 0.287 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.713 0.287 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.712 0.288 0.000
Y35-Y36 Legal intervention and operations of war
0.712 0.288 0.000
Y10-Y34 Event of undetermined intent
0.712 0.288 0.000
Y00-Y09 Assault
0.712 0.288 0.000
X85-X99 Assault
0.712 0.288 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.712 0.288 0.000
X50-X57 Overexertion, travel and privation
0.712 0.288 0.000
X30-X39 Exposure to forces of nature
0.712 0.288 0.000
X20-X29 Contact with venomous animals and plants
0.712 0.288 0.000
X10-X19 Contact with heat and hot substances
0.712 0.288 0.000
X00-X09 Exposure to smoke, fire and flames
0.712 0.288 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.712 0.288 0.000
W75-W84 Other accidental threats to breathing
0.712 0.288 0.000
W65-W74 Accidental drowning and submersion
0.712 0.288 0.000
W50-W64 Exposure to animate mechanical forces
0.712 0.288 0.000
V98-V99 Other and unspecified transport accidents
0.712 0.288 0.000
V95-V97 Air and space transport accidents
0.712 0.288 0.000
V90-V94 Water transport accidents
0.712 0.288 0.000
V70-V79 Bus occupant injured in transport accident
0.712 0.288 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.712 0.288 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.712 0.288 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.712 0.288 0.000
V01-V09 Pedestrian injured in transport accident
0.712 0.288 0.000
I42.9 Cardiomyopathy, unspecified
0.711 0.289 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.710 0.290 0.000
E10.8 With unspecified complications
0.709 0.291 0.000
E10.7 With multiple complications
0.709 0.291 0.000
E10.6 With other specified complications
0.709 0.291 0.000
E10.2 With renal complications
0.709 0.291 0.000
E10.0 With coma
0.709 0.291 0.000
L10-L14 Bullous disorders
0.709 0.291 0.000
N18.5 Chronic kidney disease, stage 5
0.709 0.291 0.000
M91-M94 Chondropathies
0.708 0.291 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.709 0.291 0.000
J17 Pneumonia in diseases classified elsewhere
0.708 0.292 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.708 0.292 0.000
J12 Viral pneumonia, not elsewhere classified
0.708 0.292 0.000
J11 Influenza, virus not identified
0.708 0.292 0.000
J09 Influenza due to certain identified influenza virus
0.708 0.292 0.000
Y59 Other and unspecified vaccines and biological substances
0.708 0.292 0.000
Y58 Bacterial vaccines
0.708 0.292 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.708 0.292 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.708 0.292 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.708 0.292 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.708 0.292 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.708 0.292 0.000
Y48 Anaesthetics and therapeutic gases
0.708 0.292 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.708 0.292 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.708 0.292 0.000
I50.9 Heart failure, unspecified
0.707 0.293 0.000
T87.4 Infection of amputation stump
0.706 0.293 0.000
I77.6 Arteritis, unspecified
0.706 0.294 0.000
S05 Injury of eye and orbit
0.705 0.295 0.000
N18.8 Other chronic renal failure
0.705 0.295 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.705 0.295 0.000
I49.0 Ventricular fibrillation and flutter
0.705 0.295 0.000
M60-M63 Disorders of muscles
0.705 0.295 0.000
E10.3 With ophthalmic complications
0.705 0.295 0.000
I30 Acute pericarditis
0.704 0.296 0.000
I51.6 Cardiovascular disease, unspecified
0.702 0.298 0.000
I51.5 Myocardial degeneration
0.702 0.298 0.000
I51.4 Myocarditis, unspecified
0.702 0.298 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.702 0.298 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.702 0.298 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.702 0.298 0.000
I51.0 Cardiac septal defect, acquired
0.702 0.298 0.000
Y45.2 Propionic acid derivatives
0.702 0.298 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.701 0.299 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.701 0.299 0.000
T81.9 Unspecified complication of procedure
0.700 0.300 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.700 0.300 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.700 0.300 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.700 0.300 0.000
N99-N99 Other disorders of the genitourinary system
0.699 0.300 0.000
S02.6 Fracture of mandible
0.699 0.301 0.000
E11.8 With unspecified complications
0.699 0.301 0.000
E11.7 With multiple complications
0.699 0.301 0.000
E11.1 With ketoacidosis
0.699 0.301 0.000
E11.0 With coma
0.699 0.301 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.698 0.302 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.698 0.302 0.000
M48.02 Spinal stenosis (Cervical region)
0.698 0.302 0.000
J18.8 Other pneumonia, organism unspecified
0.698 0.302 0.000
J18.2 Hypostatic pneumonia, unspecified
0.698 0.302 0.000
E14.8 With unspecified complications
0.697 0.303 0.000
E14.7 With multiple complications
0.697 0.303 0.000
E14.6 With other specified complications
0.697 0.303 0.000
E14.5 With peripheral circulatory complications
0.697 0.303 0.000
E14.4 With neurological complications
0.697 0.303 0.000
E14.2 Withrenal complications
0.697 0.303 0.000
E14.1 With ketoacidosis
0.697 0.303 0.000
E14.0 With coma
0.697 0.303 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.697 0.303 0.000
E34 Other endocrine disorders
0.697 0.303 0.000
E32 Diseases of thymus
0.697 0.303 0.000
E31 Polyglandular dysfunction
0.697 0.303 0.000
E30 Disorders of puberty, not elsewhere classified
0.697 0.303 0.000
E26 Hyperaldosteronism
0.697 0.303 0.000
E25 Adrenogenital disorders
0.697 0.303 0.000
E24 Cushing's syndrome
0.697 0.303 0.000
E20 Hypoparathyroidism
0.697 0.303 0.000
Q50-Q56 Congenital malformations of genital organs
0.696 0.304 0.000
L04 Acute lymphadenitis
0.696 0.304 0.000
L01 Impetigo
0.696 0.304 0.000
L00 Staphylococcal scalded skin syndrome
0.696 0.304 0.000
I78 Diseases of capillaries
0.695 0.305 0.000
E27.1 Primary adrenocortical insufficiency
0.695 0.305 0.000
Y57 Other and unspecified drugs and medicaments
0.694 0.305 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.694 0.306 0.000
S01.3 Open wound of ear
0.694 0.306 0.000
W29 Contact with other powered hand tools and household machinery
0.693 0.307 0.000
M49 Spondylopathies in diseases classified elsewhere
0.693 0.307 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.692 0.308 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.691 0.308 0.000
N05 Unspecified nephritic syndrome
0.690 0.310 0.000
I46.1 Sudden cardiac death, so described
0.689 0.310 0.000
S08 Traumatic amputation of part of head
0.689 0.311 0.000
S07 Crushing injury of head
0.689 0.311 0.000
S04 Injury of cranial nerves
0.689 0.311 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.689 0.311 0.000
T86.8 Failure and rejection of other transplanted organs and tissues
0.688 0.312 0.000
G91 Hydrocephalus
0.688 0.312 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.688 0.312 0.000
E40-E46 Malnutrition
0.687 0.313 0.000
I44.0 Atrioventricular block, first degree
0.687 0.313 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.687 0.313 0.000
E21.3 Hyperparathyroidism, unspecified
0.686 0.313 0.000
N17.8 Other acute renal failure
0.686 0.314 0.000
N17.2 Acute renal failure with medullary necrosis
0.686 0.314 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.686 0.314 0.000
N17.0 Acute renal failure with tubular necrosis
0.686 0.314 0.000
Y45.0 Opioids and related analgesics
0.686 0.314 0.000
L30 Other dermatitis
0.685 0.315 0.000
J06.9 Acute upper respiratory infection, unspecified
0.685 0.315 0.000
N70 Salpingitis and oophoritis
0.684 0.316 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.684 0.316 0.000
T90 Sequelae of injuries of head
0.684 0.316 0.000
I42.2 Other hypertrophic cardiomyopathy
0.683 0.317 0.000
M65-M68 Disorders of synovium and tendon
0.682 0.318 0.000
M89 Other disorders of bone
0.681 0.319 0.000
I44.6 Other and unspecified fascicular block
0.681 0.319 0.000
I44.5 Left posterior fascicular block
0.681 0.319 0.000
I44.4 Left anterior fascicular block
0.681 0.319 0.000
I44.3 Other and unspecified atrioventricular block
0.681 0.319 0.000
M88 Paget's disease of bone [osteitis deformans]
0.681 0.319 0.000
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.680 0.319 0.000
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.680 0.319 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.680 0.320 0.000
G93 Other disorders of brain
0.680 0.320 0.000
M84 Disorders of continuity of bone
0.680 0.320 0.000
M48.9 Spondylopathy, unspecified
0.679 0.321 0.000
M48.8 Other specified spondylopathies
0.679 0.321 0.000
M48.4 Fatigue fracture of vertebra
0.679 0.321 0.000
M48.3 Traumatic spondylopathy
0.679 0.321 0.000
M48.2 Kissing spine
0.679 0.321 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.679 0.321 0.000
J43.8 Other emphysema
0.678 0.321 0.000
J43.2 Centrilobular emphysema
0.678 0.321 0.000
J43.1 Panlobular emphysema
0.678 0.321 0.000
J43.0 MacLeod's syndrome
0.678 0.321 0.000
W25 Contact with sharp glass
0.678 0.321 0.000
X60-X84 Intentional self-harm
0.678 0.322 0.000
I27 Other pulmonary heart diseases
0.677 0.323 0.000
M23 Internal derangement of knee
0.677 0.323 0.000
M70-M79 Other soft tissue disorders
0.676 0.324 0.000
S02.4 Fracture of malar and maxillary bones
0.673 0.327 0.000
M10 Gout
0.672 0.328 0.000
L40-L45 Papulosquamous disorders
0.671 0.329 0.000
J40 Bronchitis, not specified as acute or chronic
0.670 0.329 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.669 0.331 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.669 0.331 0.000
M48.04 Spinal stenosis (Thoracic region)
0.669 0.331 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.669 0.331 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.669 0.331 0.000
I60 Subarachnoid haemorrhage
0.668 0.332 0.000
S01.4 Open wound of cheek and temporomandibular area
0.667 0.333 0.000
N18.4 Chronic kidney disease, stage 4
0.667 0.333 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.666 0.334 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.665 0.335 0.000
I71.0 Dissection of aorta [any part]
0.665 0.335 0.000
M05 Seropositive rheumatoid arthritis
0.663 0.336 0.000
I49.9 Cardiac arrhythmia, unspecified
0.663 0.337 0.000
I33 Acute and subacute endocarditis
0.663 0.337 0.000
I72.4 Aneurysm of artery of lower extremity
0.662 0.338 0.000
I42.8 Other cardiomyopathies
0.662 0.338 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.662 0.338 0.000
I42.6 Alcoholic cardiomyopathy
0.662 0.338 0.000
I42.5 Other restrictive cardiomyopathy
0.662 0.338 0.000
I42.4 Endocardial fibroelastosis
0.662 0.338 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.662 0.338 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.662 0.338 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.661 0.339 0.000
E23.0 Hypopituitarism
0.660 0.340 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.658 0.342 0.000
J60-J70 Lung diseases due to external agents
0.657 0.343 0.000
M11 Other crystal arthropathies
0.655 0.345 0.000
M14 Arthropathies in other diseases classified elsewhere
0.654 0.345 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.654 0.346 0.000
I73 Other peripheral vascular diseases
0.654 0.346 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.654 0.346 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.654 0.346 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.653 0.347 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.652 0.348 0.000
L05 Pilonidal cyst
0.652 0.348 0.000
I05-I09 Chronic rheumatic heart diseases
0.650 0.349 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.650 0.350 0.000
G70-G73 Diseases of myoneural junction and muscle
0.650 0.350 0.000
S82 Fracture of lower leg, including ankle
0.649 0.351 0.000
I77.1 Stricture of artery
0.647 0.353 0.000
G20-G26 Extrapyramidal and movement disorders
0.647 0.353 0.000
S89 Other and unspecified injuries of lower leg
0.647 0.353 0.000
S01.5 Open wound of lip and oral cavity
0.646 0.353 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.647 0.353 0.000
L03 Cellulitis
0.646 0.353 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.646 0.354 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.646 0.354 0.000
L57.0 Actinic keratosis
0.645 0.355 0.000
E65-E68 Obesity and other hyperalimentation
0.645 0.355 0.000
E29 Testicular dysfunction
0.645 0.355 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.645 0.355 0.000
J96 Respiratory failure, not elsewhere classified
0.645 0.355 0.000
S01.2 Open wound of nose
0.643 0.357 0.000
S06 Intracranial injury
0.642 0.358 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.641 0.359 0.000
N18.1 Chronic kidney disease, stage 1
0.641 0.359 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.641 0.359 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.641 0.359 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.641 0.359 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.641 0.359 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.641 0.359 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.641 0.359 0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system
0.640 0.360 0.000
Y52.8 Antivaricose drugs, including sclerosing agents
0.640 0.360 0.000
Y52.7 Peripheral vasodilators
0.640 0.360 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.640 0.360 0.000
Y52.1 Calcium-channel blockers
0.640 0.360 0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action
0.640 0.360 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.638 0.361 0.000
E21.0 Primary hyperparathyroidism
0.637 0.362 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.638 0.362 0.000
M87 Osteonecrosis
0.636 0.363 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.635 0.364 0.000
I31.9 Disease of pericardium, unspecified
0.634 0.365 0.000
Chapter I Certain infectious and parasitic diseases
0.633 0.367 0.000
N25-N29 Other disorders of kidney and ureter
0.633 0.367 0.000
I49.4 Other and unspecified premature depolarisation
0.632 0.368 0.000
V10-V19 Pedal cyclist injured in transport accident
0.631 0.368 0.000
S32.0 Fracture of lumbar vertebra
0.630 0.370 0.000
T86.0 Bone-marrow transplant rejection
0.630 0.370 0.000
G95 Other diseases of spinal cord
0.630 0.370 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.630 0.370 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.630 0.370 0.000
N46 Male infertility
0.630 0.370 0.000
N44 Torsion of testis
0.630 0.370 0.000
I77.8 Other specified disorders of arteries and arterioles
0.629 0.371 0.000
Y43 Primarily systemic agents
0.629 0.371 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.628 0.372 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.628 0.372 0.000
L83 Acanthosis nigricans
0.628 0.372 0.000
N70.1 Chronic salpingitis and oophoritis
0.627 0.373 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.627 0.373 0.000
Y44.9 Other and unspecified agents affecting blood constituents
0.627 0.373 0.000
Y44.7 Plasma substitutes
0.627 0.373 0.000
Y44.6 Natural blood and blood products
0.627 0.373 0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]
0.627 0.373 0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants
0.627 0.373 0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations
0.627 0.373 0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations
0.627 0.373 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.626 0.374 0.000
Y45.8 Other analgesics and antipyretics
0.626 0.374 0.000
Y45.5 4-Aminophenol derivatives
0.626 0.374 0.000
Y45.4 Antirheumatics
0.626 0.374 0.000
I47 Paroxysmal tachycardia
0.626 0.374 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.625 0.375 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.624 0.376 0.000
J86 Pyothorax
0.624 0.376 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.624 0.376 0.000
M21 Other acquired deformities of limbs
0.624 0.376 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.623 0.377 0.000
L94 Other localised connective tissue disorders
0.623 0.377 0.000
L93 Lupus erythematosus
0.623 0.377 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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