TreeWAS – Variant ID: rs7551188

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.222	0.778	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.219	0.781	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.219	0.781	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.207	0.793	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.202	0.798	0.000
T39.0 Salicylates	0.195	0.805	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.185	0.815	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.183	0.816	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.183	0.817	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.181	0.819	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.181	0.819	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.176	0.824	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.174	0.826	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.173	0.827	0.000
T46.1 Calcium-channel blockers	0.171	0.829	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.169	0.831	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.169	0.831	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.166	0.834	0.000
T45.0 Antiallergic and antiemetic drugs	0.166	0.834	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.163	0.837	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.162	0.838	0.000
T39.4 Antirheumatics, not elsewhere classified	0.159	0.840	0.000
T39.2 Pyrazolone derivatives	0.159	0.840	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.158	0.842	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.157	0.843	0.000
T47.2 Stimulant laxatives	0.154	0.846	0.000
T39.1 4-Aminophenol derivatives	0.154	0.846	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.152	0.848	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.151	0.849	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.150	0.850	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.149	0.851	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.149	0.851	0.000
T46.7 Peripheral vasodilators	0.149	0.851	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.149	0.851	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.148	0.852	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.147	0.852	0.000
T47.0 Histamine H(2)-receptor antagonists	0.146	0.854	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.145	0.855	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.145	0.855	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.145	0.855	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.145	0.855	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.145	0.855	0.000
T44.0 Anticholinesterase agents	0.145	0.855	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.143	0.857	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.142	0.858	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.141	0.859	0.000
T50.1 Loop [high-ceiling] diuretics	0.140	0.860	0.000
T45.2 Vitamins, not elsewhere classified	0.139	0.861	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.133	0.867	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.132	0.868	0.000
T45.8 Other primarily systemic and haematological agents	0.132	0.868	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.132	0.868	0.000
T45.6 Fibrinolysis-affecting drugs	0.132	0.868	0.000
T45.4 Iron and its compounds	0.132	0.868	0.000
T45.3 Enzymes, not elsewhere classified	0.132	0.868	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.132	0.868	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.132	0.868	0.000
T47.7 Emetics	0.132	0.868	0.000
T47.6 Antidiarrhoeal drugs	0.132	0.868	0.000
T47.5 Digestants	0.132	0.868	0.000
T47.4 Other laxatives	0.132	0.868	0.000
T47.3 Saline and osmotic laxatives	0.132	0.868	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.131	0.869	0.000
T43.2 Other and unspecified antidepressants	0.131	0.869	0.000
T36 Poisoning by systemic antibiotics	0.131	0.869	0.000
T40.2 Other opioids	0.131	0.869	0.000
T38.5 Other oestrogens and progestogens	0.130	0.870	0.000
T50.4 Drugs affecting uric acid metabolism	0.130	0.870	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.129	0.871	0.000
T50.7 Analeptics and opioid receptor antagonists	0.126	0.873	0.000
T50.5 Appetite depressants	0.126	0.873	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.126	0.873	0.000
T50.0 Mineralocorticoids and their antagonists	0.126	0.873	0.000
T48.5 Anti-common-cold drugs	0.125	0.875	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.125	0.875	0.000
T37.5 Antiviral drugs	0.125	0.875	0.000
T37.4 Anthelminthics	0.125	0.875	0.000
T37.3 Other antiprotozoal drugs	0.125	0.875	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.125	0.875	0.000
T37.1 Antimycobacterial drugs	0.125	0.875	0.000
T37.0 Sulphonamides	0.125	0.875	0.000
T40.3 Methadone	0.125	0.875	0.000
T38.1 Thyroid hormones and substitutes	0.125	0.875	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.122	0.878	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.121	0.878	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.121	0.879	0.000
T48.4 Expectorants	0.121	0.879	0.000
T48.3 Antitussives	0.121	0.879	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.121	0.879	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.121	0.879	0.000
T48.0 Oxytocic drugs	0.121	0.879	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.120	0.880	0.000
T40.1 Heroin	0.120	0.880	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.119	0.881	0.000
T38.9 Other and unspecified hormone antagonists	0.117	0.883	0.000
T38.7 Androgens and anabolic congeners	0.117	0.883	0.000
T38.4 Oral contraceptives	0.117	0.883	0.000
T38.2 Antithyroid drugs	0.117	0.883	0.000
T38.0 Glucocorticoids and synthetic analogues	0.117	0.883	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.117	0.883	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.116	0.884	0.000
T40.8 Lysergide [LSD]	0.116	0.884	0.000
T40.7 Cannabis (derivatives)	0.116	0.884	0.000
T40.0 Opium	0.116	0.884	0.000
T50.8 Diagnostic agents	0.114	0.885	0.000
T41.5 Therapeutic gases	0.113	0.887	0.000
T41.4 Anaesthetic, unspecified	0.113	0.887	0.000
T41.3 Local anaesthetics	0.113	0.887	0.000
T41.2 Other and unspecified general anaesthetics	0.113	0.887	0.000
T41.1 Intravenous anaesthetics	0.113	0.887	0.000
T41.0 Inhaled anaesthetics	0.113	0.887	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.113	0.887	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.112	0.888	0.000
T40.5 Cocaine	0.111	0.889	0.000
T40.6 Other and unspecified narcotics	0.111	0.889	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.109	0.890	0.000
T43.9 Psychotropic drug, unspecified	0.109	0.891	0.000
T49.9 Topical agent, unspecified	0.106	0.894	0.000
T49.8 Other topical agents	0.106	0.894	0.000
T49.7 Dental drugs, topically applied	0.106	0.894	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.106	0.894	0.000
T49.5 Ophthalmological drugs and preparations	0.106	0.894	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.106	0.894	0.000
T49.3 Emollients, demulcents and protectants	0.106	0.894	0.000
T49.2 Local astringents and local detergents	0.106	0.894	0.000
T49.1 Antipruritics	0.106	0.894	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.101	0.899	0.000
T40.4 Other synthetic narcotics	0.099	0.901	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.099	0.901	0.000
T42.3 Barbiturates	0.097	0.902	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.097	0.903	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.096	0.903	0.000
T45.5 Anticoagulants	0.095	0.904	0.000
T42.1 Iminostilbenes	0.095	0.905	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.094	0.906	0.000
T42.2 Succinimides and oxazolidinediones	0.094	0.906	0.000
T36.9 Systemic antibiotic, unspecified	0.094	0.906	0.000
T36.8 Other systemic antibiotics	0.094	0.906	0.000
T36.7 Antifungal antibiotics, systemically used	0.094	0.906	0.000
T36.6 Rifamycins	0.094	0.906	0.000
T36.5 Aminoglycosides	0.094	0.906	0.000
T36.2 Chloramphenicol group	0.094	0.906	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.094	0.906	0.000
T36.3 Macrolides	0.093	0.907	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.092	0.907	0.000
T36.4 Tetracyclines	0.089	0.910	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.089	0.911	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.086	0.913	0.000
T43.6 Psychostimulants with abuse potential	0.084	0.916	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.083	0.917	0.000
T42.0 Hydantoin derivatives	0.081	0.919	0.000
T36.0 Penicillins	0.075	0.924	0.000
I89.0 Lymphoedema, not elsewhere classified	0.069	0.931	0.000
T42.4 Benzodiazepines	0.034	0.966	0.000
Q61 Cystic kidney disease	0.018	0.982	0.000
Q61.3 Polycystic kidney, unspecified	0.016	0.983	0.000
Q61.0 Congenital single renal cyst	0.016	0.984	0.000
Q60-Q64 Congenital malformations of the urinary system	0.016	0.984	0.000
Q61.9 Cystic kidney disease, unspecified	0.015	0.985	0.000
Q61.2 Polycystic kidney, adult type	0.015	0.985	0.000
Q61.5 Medullary cystic kidney	0.015	0.985	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.015	0.985	0.000
Q61.4 Renal dysplasia	0.014	0.986	0.000
Q60.0 Renal agenesis, unilateral	0.013	0.987	0.000
Q61.8 Other cystic kidney diseases	0.013	0.987	0.000
Q61.1 Polycystic kidney, infantile type	0.013	0.987	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.013	0.987	0.000
Q64 Other congenital malformations of urinary system	0.013	0.987	0.000
Q60.2 Renal agenesis, unspecified	0.012	0.988	0.000
Q63 Other congenital malformations of kidney	0.011	0.989	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.011	0.989	0.000
H40.2 Primary angle-closure glaucoma	0.011	0.989	0.000
Q60.6 Potter's syndrome	0.011	0.989	0.000
Q60.5 Renal hypoplasia, unspecified	0.011	0.989	0.000
Q60.4 Renal hypoplasia, bilateral	0.011	0.989	0.000
Q60.3 Renal hypoplasia, unilateral	0.011	0.989	0.000
Q60.1 Renal agenesis, bilateral	0.011	0.989	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.010	0.989	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.010	0.990	0.000
Q62.5 Duplication of ureter	0.010	0.990	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.010	0.990	0.000
Q62.1 Atresia and stenosis of ureter	0.010	0.990	0.000
Q62.8 Other congenital malformations of ureter	0.009	0.990	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.009	0.990	0.000
Q62.6 Malposition of ureter	0.009	0.990	0.000
Q62.4 Agenesis of ureter	0.009	0.990	0.000
Q62.2 Congenital megaloureter	0.009	0.990	0.000
Q62.0 Congenital hydronephrosis	0.009	0.990	0.000
H72.0 Central perforation of tympanic membrane	0.010	0.990	0.000
Q64.9 Congenital malformation of urinary system, unspecified	0.009	0.991	0.000
Q64.8 Other specified congenital malformations of urinary system	0.009	0.991	0.000
Q64.6 Congenital diverticulum of bladder	0.009	0.991	0.000
Q64.5 Congenital absence of bladder and urethra	0.009	0.991	0.000
Q64.4 Malformation of urachus	0.009	0.991	0.000
Q64.2 Congenital posterior urethral valves	0.009	0.991	0.000
Q64.1 Exstrophy of urinary bladder	0.009	0.991	0.000
Q64.0 Epispadias	0.009	0.991	0.000
Q63.2 Ectopic kidney	0.009	0.991	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.009	0.991	0.000
Q63.8 Other specified congenital malformations of kidney	0.009	0.991	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.009	0.991	0.000
H72 Perforation of tympanic membrane	0.009	0.991	0.000
Q63.3 Hyperplastic and giant kidney	0.008	0.992	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.008	0.992	0.000
G47.9 Sleep disorder, unspecified	0.000	0.992	0.008
Y52.3 Coronary vasodilators, not elsewhere classified	0.008	0.992	0.000
D68.8 Other specified coagulation defects	0.008	0.992	0.000
D68.2 Hereditary deficiency of other clotting factors	0.007	0.993	0.000
D68.9 Coagulation defect, unspecified	0.007	0.993	0.000
H72.8 Other perforations of tympanic membrane	0.007	0.993	0.000
D68 Other coagulation defects	0.007	0.993	0.000
K65.9 Peritonitis, unspecified	0.007	0.993	0.000
D33.3 Cranial nerves	0.000	0.993	0.007
E10.3 With ophthalmic complications	0.006	0.994	0.000
D68.5 Primary Thrombophilia	0.006	0.994	0.000
H72.1 Attic perforation of tympanic membrane	0.006	0.994	0.000
S51.9 Open wound of forearm, part unspecified	0.006	0.994	0.000
S51.8 Open wound of other parts of forearm	0.006	0.994	0.000
H72.2 Other marginal perforations of tympanic membrane	0.005	0.994	0.000
Z94.8 Other transplanted organ and tissue status	0.000	0.995	0.005
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.005	0.995	0.000
R61.9 Hyperhidrosis, unspecified	0.005	0.995	0.000
S51 Open wound of forearm	0.005	0.995	0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.005	0.995	0.000
D68.1 Hereditary factor XI deficiency	0.005	0.995	0.000
D41.4 Bladder	0.005	0.995	0.000
Z49.2 Other dialysis	0.005	0.995	0.000
G47.1 Disorders of excessive somnolence [hypersomnias]	0.000	0.995	0.005
D68.6 Other Thrombophilia	0.004	0.996	0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.004	0.996	0.000
D33 Benign neoplasm of brain and other parts of central nervous system	0.000	0.996	0.004
C43.7 Malignant melanoma of lower limb, including hip	0.000	0.996	0.004
Z49.0 Preparatory care for dialysis	0.004	0.996	0.000
D33.2 Brain, unspecified	0.000	0.996	0.004
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.000	0.996	0.004
D68.4 Acquired coagulation factor deficiency	0.004	0.996	0.000
D33.4 Spinal cord	0.000	0.996	0.004
C43.6 Malignant melanoma of upper limb, including shoulder	0.000	0.996	0.004
Q63.0 Accessory kidney	0.003	0.996	0.000
S51.7 Multiple open wounds of forearm	0.004	0.996	0.000
N70.9 Salpingitis and oophoritis, unspecified	0.004	0.996	0.000
D68.0 Von Willebrand's disease	0.004	0.996	0.000
Z49 Care involving dialysis	0.004	0.996	0.000
M23.49 Loose body in knee-Unspec lig/men	0.003	0.997	0.000
E10 Insulin-dependent diabetes mellitus	0.003	0.997	0.000
G47 Sleep disorders	0.000	0.997	0.003
D33.9 Central nervous system, unspecified	0.000	0.997	0.003
D33.7 Other specified parts of central nervous system	0.000	0.997	0.003
D33.1 Brain, infratentorial	0.000	0.997	0.003
E10.1 With ketoacidosis	0.003	0.997	0.000
C43 Malignant melanoma of skin	0.000	0.997	0.003
C43.2 Malignant melanoma of ear and external auricular canal	0.000	0.997	0.003
I89.1 Lymphangitis	0.003	0.997	0.000
E10.4 With neurological complications	0.003	0.997	0.000
E10.2 With renal complications	0.003	0.997	0.000
J47 Bronchiectasis	0.003	0.997	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.003	0.997	0.000
M47.99 Spondylosis, unspecified (Site unspecified)	0.000	0.997	0.003
C43.3 Malignant melanoma of other and unspecified parts of face	0.000	0.997	0.003
B91 Sequelae of poliomyelitis	0.003	0.997	0.000
S51.0 Open wound of elbow	0.003	0.997	0.000
E10.0 With coma	0.003	0.997	0.000
E10.7 With multiple complications	0.003	0.997	0.000
C43.1 Malignant melanoma of eyelid, including canthus	0.000	0.997	0.003
K91.2 Postsurgical malabsorption, not elsewhere classified	0.000	0.997	0.003
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.997	0.003
S02.10 Fracture of base of skull (closed)	0.000	0.997	0.003
D33.0 Brain, supratentorial	0.000	0.997	0.002
E10.6 With other specified complications	0.003	0.997	0.000
M79.82 Other specified soft tissue disorders (Upper arm)	0.000	0.997	0.003
E10.8 With unspecified complications	0.003	0.997	0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.000	0.997	0.003
K91.1 Postgastric surgery syndromes	0.000	0.997	0.003
M67.2 Synovial hypertrophy, not elsewhere classified	0.003	0.997	0.000
E10.5 With peripheral circulatory complications	0.003	0.997	0.000
M17.3 Other posttraumatic gonarthrosis	0.003	0.997	0.000
C43.8 Overlapping malignant melanoma of skin	0.000	0.997	0.002
C43.0 Malignant melanoma of lip	0.000	0.997	0.002
Z49.1 Extracorporeal dialysis	0.003	0.997	0.000
K91.5 Postcholecystectomy syndrome	0.000	0.998	0.002
K65 Peritonitis	0.002	0.998	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.998	0.002
K91.9 Postprocedural disorder of digestive system, unspecified	0.000	0.998	0.002
G80.1 Spastic diplegia	0.002	0.998	0.000
M54.56 Low back pain (Lumbar region)	0.000	0.998	0.002
S82.00 Fracture of patella (closed)	0.000	0.998	0.002
Z42.0 Follow-up care involving plastic surgery of head and neck	0.002	0.998	0.000
G47.2 Disorders of the sleep-wake schedule	0.000	0.998	0.002
H49.2 Sixth [abducent] nerve palsy	0.000	0.998	0.002
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.002	0.998	0.000
M19.96 Arthrosis, unspecified-Lower leg	0.002	0.998	0.000
N70.1 Chronic salpingitis and oophoritis	0.002	0.998	0.000
R94.3 Abnormal results of cardiovascular function studies	0.002	0.998	0.000
D15.1 Heart	0.002	0.998	0.000
Q12.0 Congenital cataract	0.002	0.998	0.000
S60.8 Other superficial injuries of wrist and hand	0.000	0.998	0.002
G47.4 Narcolepsy and cataplexy	0.000	0.998	0.002
G90.2 Horner's syndrome	0.002	0.998	0.000
H40 Glaucoma	0.002	0.998	0.000
K65.8 Other peritonitis	0.002	0.998	0.000
N70 Salpingitis and oophoritis	0.002	0.998	0.000
C43.4 Malignant melanoma of scalp and neck	0.000	0.998	0.002
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
G02.0 Meningitis in viral diseases classified elsewhere	0.002	0.998	0.000
N34.2 Other urethritis	0.002	0.998	0.000
K91.4 Colostomy and enterostomy malfunction	0.000	0.998	0.002
S53.4 Sprain and strain of elbow	0.002	0.998	0.000
Q28 Other congenital malformations of circulatory system	0.002	0.998	0.000
G47.8 Other sleep disorders	0.000	0.998	0.002
H40.9 Glaucoma, unspecified	0.002	0.998	0.000
G80.0 Spastic cerebral palsy	0.002	0.998	0.000
G80 Infantile cerebral palsy	0.002	0.998	0.000
H65.4 Other chronic nonsuppurative otitis media	0.002	0.998	0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.002	0.998	0.000
G90.0 Idiopathic peripheral autonomic neuropathy	0.002	0.998	0.000
H40.8 Other glaucoma	0.002	0.998	0.000
H40.5 Glaucoma secondary to other eye disorders	0.002	0.998	0.000
G80.9 Infantile cerebral palsy, unspecified	0.002	0.998	0.000
H40.6 Glaucoma secondary to drugs	0.002	0.998	0.000
I49.8 Other specified cardiac arrhythmias	0.000	0.998	0.002
G80.2 Infantile hemiplegia	0.002	0.998	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.002	0.998	0.000
S53.0 Dislocation of radial head	0.002	0.998	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.002	0.998	0.000
H40.3 Glaucoma secondary to eye trauma	0.002	0.998	0.000
M67.8 Other specified disorders of synovium and tendon	0.002	0.998	0.000
R61 Hyperhidrosis	0.002	0.998	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.000	0.998	0.002
G90 Disorders of autonomic nervous system	0.002	0.998	0.000
K91.0 Vomiting following gastro-intestinal surgery	0.000	0.998	0.002
S53.2 Traumatic rupture of radial collateral ligament	0.002	0.998	0.000
G80.8 Other infantile cerebral palsy	0.002	0.998	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.002	0.998	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.002	0.998	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.002	0.998	0.000
Q28.1 Other malformations of precerebral vessels	0.002	0.998	0.000
M23.4 Loose body in knee	0.002	0.998	0.000
S53.3 Traumatic rupture of ulnar collateral ligament	0.002	0.998	0.000
G90.8 Other disorders of autonomic nervous system	0.002	0.998	0.000
Q28.3 Other malformations of cerebral vessels	0.002	0.998	0.000
E27.8 Other specified disorders of adrenal gland	0.000	0.998	0.002
G80.4 Ataxic cerebral palsy	0.002	0.998	0.000
G80.3 Dyskinetic cerebral palsy	0.002	0.998	0.000
M67 Other disorders of synovium and tendon	0.002	0.998	0.000
Y52 Agents primarily affecting the cardiovascular system	0.002	0.998	0.000
H40.4 Glaucoma secondary to eye inflammation	0.002	0.998	0.000
S53.1 Dislocation of elbow, unspecified	0.002	0.998	0.000
S56.1 Injury of flexor muscle and tendon of other finger(s) at forearm level	0.002	0.998	0.000
M23.41 Loose body in knee-Ant lig/hrn men	0.002	0.998	0.000
H65.0 Acute serous otitis media	0.002	0.998	0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
Q12 Congenital lens malformations	0.002	0.998	0.000
S56.8 Injury of other and unspecified muscles and tendons at forearm level	0.002	0.998	0.000
G90.9 Disorder of autonomic nervous system, unspecified	0.002	0.998	0.000
M67.4 Ganglion	0.002	0.998	0.000
M67.47 Ganglion, ankle and foot	0.002	0.998	0.000
G71.3 Mitochondrial myopathy, not elsewhere classified	0.000	0.998	0.002
N70.0 Acute salpingitis and oophoritis	0.001	0.998	0.000
L23.1 Allergic contact dermatitis due to adhesives	0.002	0.998	0.000
H65 Nonsuppurative otitis media	0.002	0.998	0.000
R61.1 Generalised hyperhidrosis	0.001	0.998	0.000
G71.1 Myotonic disorders	0.000	0.998	0.002
G90.4 Autonomic dysreflexia	0.001	0.998	0.000
G90.1 Familial dysautonomia [Riley-Day]	0.001	0.998	0.000
H21.0 Hyphaema	0.002	0.998	0.000
M23.40 Loose body in knee-Mult sites	0.001	0.998	0.000
M90.78 Fracture of bone in neoplastic disease (Other)	0.002	0.998	0.000
C43.9 Malignant melanoma of skin, unspecified	0.000	0.998	0.001
D23.5 Skin of trunk	0.002	0.998	0.000
G90.3 Multisystem degeneration	0.001	0.998	0.000
Z99.8 Dependence on other enabling machines and devices	0.002	0.998	0.000
S56 Injury of muscle and tendon at forearm level	0.002	0.998	0.000
M23.47 Loose body in knee-Capsular lig	0.001	0.998	0.000
M23.45 Loose body in knee-Pst hrn lat men	0.001	0.998	0.000
M23.42 Loose body in knee-Pst lig/hrn men	0.001	0.998	0.000
E27.9 Disorder of adrenal gland, unspecified	0.000	0.998	0.002
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.001	0.998	0.000
S50-S59 Injuries to the elbow and forearm	0.002	0.998	0.000
S53.11 Anterior subluxation and dislocation of ulnohumeral joint	0.001	0.998	0.000
S53.10 Unspecified subluxation and dislocation of ulnohumeral joint	0.001	0.998	0.000
H49.1 Fourth [trochlear] nerve palsy	0.000	0.998	0.001
I72.4 Aneurysm of artery of lower extremity	0.002	0.998	0.000
M67.9 Disorder of synovium and tendon, unspecified	0.001	0.998	0.000
M67.3 Transient synovitis	0.001	0.998	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.001	0.998	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.001	0.998	0.000
M23.46 Loose body in knee-O/unsp lat men	0.001	0.998	0.000
B35.1 Tinea unguium	0.001	0.998	0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.001	0.998	0.000
G01 Meningitis in bacterial diseases classified elsewhere	0.001	0.998	0.000
M13.90 Arthritis, unspecified (Multiple sites)	0.000	0.999	0.001
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000
G02.1 Meningitis in mycoses	0.001	0.999	0.000
G71.0 Muscular dystrophy	0.000	0.999	0.001
K91.3 Postoperative intestinal obstruction	0.000	0.999	0.001
O82.0 Delivery by elective Caesarean section	0.001	0.999	0.000
Q12.9 Congenital lens malformation, unspecified	0.001	0.999	0.000
Q12.8 Other congenital lens malformations	0.001	0.999	0.000
Q12.4 Spherophakia	0.001	0.999	0.000
Q12.3 Congenital aphakia	0.001	0.999	0.000
Q12.2 Coloboma of lens	0.001	0.999	0.000
Q12.1 Congenital displaced lens	0.001	0.999	0.000
M23.44 Loose body in knee-Lat lig/ant men	0.001	0.999	0.000
M23.43 Loose body in knee-Med lig/oth men	0.001	0.999	0.000
M67.49 Ganglion, multiple sites	0.001	0.999	0.000
M67.45 Ganglion, hip	0.001	0.999	0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.000	0.999	0.001
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.001	0.999	0.000
S32.50 Fracture of pubis (closed)	0.000	0.999	0.001
M67.0 Short Achilles tendon (acquired)	0.001	0.999	0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.001	0.999	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.000	0.999	0.001
D15.0 Thymus	0.001	0.999	0.000
G47.3 Sleep apnoea	0.000	0.999	0.001
M67.43 Ganglion, wrist	0.001	0.999	0.000
M90.71 Fracture of bone in neoplastic disease (Shoulder region)	0.001	0.999	0.000
H16.9 Keratitis, unspecified	0.001	0.999	0.000
G71 Primary disorders of muscles	0.000	0.999	0.001
G37.9 Demyelinating disease of central nervous system, unspecified	0.001	0.999	0.000
H65.2 Chronic serous otitis media	0.001	0.999	0.000
R61.0 Localised hyperhidrosis	0.001	0.999	0.000
S56.7 Injury of multiple muscles and tendons at forearm level	0.001	0.999	0.000
Q22.5 Ebstein's anomaly	0.001	0.999	0.000
S56.2 Injury of other flexor muscle and tendon at forearm level	0.001	0.999	0.000
S56.0 Injury of flexor muscle and tendon of thumb at forearm level	0.001	0.999	0.000
Y52.7 Peripheral vasodilators	0.001	0.999	0.000
S55 Injury of blood vessels at forearm level	0.001	0.999	0.000
M46.46 Discitis, unspecified (Lumbar region)	0.001	0.999	0.000
G03.9 Meningitis, unspecified	0.001	0.999	0.000
H21.4 Pupillary membranes	0.001	0.999	0.000
J69.0 Pneumonitis due to food and vomit	0.001	0.999	0.000
N64.5 Other signs and symptoms in breast	0.000	0.999	0.001
Q85.9 Phakomatosis, unspecified	0.000	0.999	0.001
H21 Other disorders of iris and ciliary body	0.001	0.999	0.000
S58 Traumatic amputation of forearm	0.001	0.999	0.000
S57 Crushing injury of forearm	0.001	0.999	0.000
M67.96 Unspecified disorder of synovium and tendon, lower leg	0.001	0.999	0.000
J69.8 Pneumonitis due to other solids and liquids	0.001	0.999	0.000
M90.7 Fracture of bone in neoplastic disease	0.001	0.999	0.000
T79.3 Post-traumatic wound infection, not elsewhere classified	0.001	0.999	0.000
S22.50 Flail chest (closed)	0.001	0.999	0.000
G00.2 Streptococcal meningitis	0.001	0.999	0.000
S56.3 Injury of extensor or abductor muscles and tendons of thumb at forearm level	0.001	0.999	0.000
Y52.1 Calcium-channel blockers	0.001	0.999	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.001	0.999	0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.001	0.999	0.000
Q85 Phakomatoses, not elsewhere classified	0.000	0.999	0.001
Q22.1 Congenital pulmonary valve stenosis	0.001	0.999	0.000
S55.0 Injury of ulnar artery at forearm level	0.001	0.999	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.001	0.999	0.000
G00 Bacterial meningitis, not elsewhere classified	0.001	0.999	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.001	0.999	0.000
H17.9 Corneal scar and opacity, unspecified	0.001	0.999	0.000
G03 Meningitis due to other and unspecified causes	0.001	0.999	0.000
J69 Pneumonitis due to solids and liquids	0.001	0.999	0.000
C83.1 Small cleaved cell (diffuse)	0.000	0.999	0.001
G71.9 Primary disorder of muscle, unspecified	0.000	0.999	0.001
G71.8 Other primary disorders of muscles	0.000	0.999	0.001
G71.2 Congenital myopathies	0.000	0.999	0.001
G09 Sequelae of inflammatory diseases of central nervous system	0.001	0.999	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.001	0.999	0.000
S56.20 Unspecified injury of other flexor muscle, fascia and tendon at forearm level	0.001	0.999	0.000
G00.1 Pneumococcal meningitis	0.001	0.999	0.000
H65.1 Other acute nonsuppurative otitis media	0.001	0.999	0.000
Q25.4 Other congenital malformations of aorta	0.000	0.999	0.001
H49 Paralytic strabismus	0.000	0.999	0.001
S54 Injury of nerves at forearm level	0.001	0.999	0.000
M90.70 Fracture of bone in neoplastic disease (Multiple sites)	0.001	0.999	0.000
F01.9 Vascular dementia, unspecified	0.000	0.999	0.001
I07.1 Tricuspid insufficiency	0.001	0.999	0.000
S55.9 Injury of unspecified blood vessel at forearm level	0.001	0.999	0.000
S55.8 Injury of other blood vessels at forearm level	0.001	0.999	0.000
S55.7 Injury of multiple blood vessels at forearm level	0.001	0.999	0.000
S55.2 Injury of vein at forearm level	0.001	0.999	0.000
S56.5 Injury of other extensor muscle and tendon at forearm level	0.001	0.999	0.000
S57.9 Crushing injury of forearm, part unspecified	0.001	0.999	0.000
S57.8 Crushing injury of forearm, part unspecified	0.001	0.999	0.000
S57.7 Crushing injury of other parts of forearm	0.001	0.999	0.000
S57.0 Crushing injury of elbow	0.001	0.999	0.000
S58.9 Traumatic amputation of forearm, level unspecified	0.001	0.999	0.000
S58.1 Traumatic amputation at level between elbow and wrist	0.001	0.999	0.000
S58.0 Traumatic amputation at elbow level	0.001	0.999	0.000
M90.79 Fracture of bone in neoplastic disease (Site unspecified)	0.001	0.999	0.000
M90.77 Fracture of bone in neoplastic disease (Ankle and foot)	0.001	0.999	0.000
M90.76 Fracture of bone in neoplastic disease (Lower leg)	0.001	0.999	0.000
M90.74 Fracture of bone in neoplastic disease (Hand)	0.001	0.999	0.000
M90.73 Fracture of bone in neoplastic disease (Forearm)	0.001	0.999	0.000
S92.50 Fracture of other toe (closed)	0.000	0.999	0.001
D15.9 Intrathoracic organ, unspecified	0.001	0.999	0.000
D15.7 Other specified intrathoracic organs	0.001	0.999	0.000
D15.2 Mediastinum	0.001	0.999	0.000
G30.9 Alzheimer's disease, unspecified	0.000	0.999	0.001
H21.3 Cyst of iris, ciliary body and anterior chamber	0.001	0.999	0.000
Z84.8 Family history of other specified conditions	0.000	0.999	0.001
Z99.2 Dependence on renal dialysis	0.001	0.999	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.001	0.999	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.001	0.999	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.001	0.999	0.000
G00.8 Other bacterial meningitis	0.001	0.999	0.000
G00.3 Staphylococcal meningitis	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations