TreeWAS – Variant ID: rs7554182

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.999	0.001
# Top node	0.998	0.002
Chapter I Certain infectious and parasitic diseases	0.993	0.007
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.981	0.019
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.964	0.036
R50-R69 General symptoms and signs	0.959	0.041
Chapter VI Diseases of the nervous system	0.956	0.044
T36-T50 Poisoning by drugs, medicaments and biological substances	0.954	0.046
R69 Unknown and unspecified causes of morbidity	0.953	0.047
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.950	0.050
A00-A09 Intestinal infectious diseases	0.948	0.052
R42 Dizziness and giddiness	0.945	0.055
Chapter V Mental and behavioural disorders	0.943	0.057
R94 Abnormal results of function studies	0.936	0.064
B35-B49 Mycoses	0.932	0.068
R94.5 Abnormal results of liver function studies	0.927	0.073
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.926	0.074
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.921	0.079
S60-S69 Injuries to the wrist and hand	0.921	0.079
S80-S89 Injuries to the knee and lower leg	0.912	0.088
G50-G59 Nerve, nerve root and plexus disorders	0.905	0.095
F30-F39 Mood [affective] disorders	0.892	0.108
B37 Candidiasis	0.888	0.112
G40-G47 Episodic and paroxysmal disorders	0.886	0.114
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.876	0.124
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.875	0.125
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.875	0.125
B25-B34 Other viral diseases	0.873	0.127
T51 Toxic effect of alcohol	0.865	0.135
A04 Other bacterial intestinal infections	0.861	0.139
S20-S29 Injuries to the thorax	0.854	0.146
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.848	0.152
S66 Injury of muscle and tendon at wrist and hand level	0.841	0.159
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.833	0.167
R68 Other general symptoms and signs	0.830	0.170
G45 Transient cerebral ischaemic attacks and related syndromes	0.828	0.172
R55 Syncope and collapse	0.827	0.173
Chapter IV Endocrine, nutritional and metabolic diseases	0.827	0.173
A09.9 Gastroenteritis and colitis of unspecified origin	0.825	0.175
T51.0 Ethanol	0.825	0.175
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.823	0.177
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.815	0.185
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.810	0.190
F32 Depressive episode	0.809	0.191
Chapter VII Diseases of the eye and adnexa	0.807	0.193
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.804	0.196
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.801	0.199
B37.0 Candidal stomatitis	0.799	0.201
R51 Headache	0.798	0.202
S40-S49 Injuries to the shoulder and upper arm	0.793	0.207
B34 Viral infection of unspecified site	0.787	0.213
G57 Mononeuropathies of lower limb	0.782	0.218
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.780	0.220
G45.9 Transient cerebral ischaemic attack, unspecified	0.779	0.221
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.775	0.225
S82 Fracture of lower leg, including ankle	0.774	0.226
S70-S79 Injuries to the hip and thigh	0.773	0.227
F99-F99 Unspecified mental disorder	0.770	0.230
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.770	0.230
Chapter XX External causes of morbidity and mortality	0.770	0.230
S81 Open wound of lower leg	0.769	0.231
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.763	0.237
R44 Other symptoms and signs involving general sensations and perceptions	0.763	0.237
A30-A49 Other bacterial diseases	0.761	0.239
A04.7 Enterocolitis due to Clostridium difficile	0.761	0.239
R41 Other symptoms and signs involving cognitive functions and awareness	0.758	0.242
M80-M85 Disorders of bone density and structure	0.756	0.244
R57 Shock, not elsewhere classified	0.754	0.246
E10-E14 Diabetes mellitus	0.753	0.247
B15-B19 Viral hepatitis	0.753	0.247
B37.8 Candidiasis of other sites	0.750	0.250
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.747	0.253
M86-M90 Other osteopathies	0.746	0.254
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.745	0.255
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.744	0.256
M65-M68 Disorders of synovium and tendon	0.744	0.256
T88 Other complications of surgical and medical care, not elsewhere classified	0.742	0.258
R93 Abnormal findings on diagnostic imaging of other body structures	0.740	0.260
G80-G83 Cerebral palsy and other paralytic syndromes	0.740	0.260
R52 Pain, not elsewhere classified	0.737	0.263
G58 Other mononeuropathies	0.737	0.263
G43 Migraine	0.736	0.264
S90-S99 Injuries to the ankle and foot	0.735	0.265
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.734	0.265
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.732	0.268
F33 Recurrent depressive disorder	0.732	0.268
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.728	0.272
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.728	0.272
R45 Symptoms and signs involving emotional state	0.727	0.272
S00-S09 Injuries to the head	0.727	0.273
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.726	0.274
B34.9 Viral infection, unspecified	0.726	0.274
H53-H54 Visual disturbances and blindness	0.726	0.274
T85 Complications of other internal prosthetic devices, implants and grafts	0.724	0.276
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.724	0.276
B37.9 Candidiasis, unspecified	0.723	0.276
Chapter XXII Codes for special purposes	0.723	0.277
M50-M54 Other dorsopathies	0.720	0.280
G59 Mononeuropathy in diseases classified elsewhere	0.719	0.281
F31 Bipolar affective disorder	0.719	0.281
B95-B98 Bacterial, viral and other infectious agents	0.717	0.283
T79-T79 Certain early complications of trauma	0.716	0.284
T33-T35 Frostbite	0.716	0.284
T26-T28 Burns and corrosions confined to eye and internal organs	0.716	0.284
T20-T25 Burns and corrosions of external body surface, specified by site	0.716	0.284
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.716	0.284
T00-T07 Injuries involving multiple body regions	0.716	0.284
S10-S19 Injuries to the neck	0.716	0.284
Chapter XVI Certain conditions originating in the perinatal period	0.716	0.284
T43.5 Other and unspecified antipsychotics and neuroleptics	0.715	0.285
S60 Superficial injury of wrist and hand	0.715	0.285
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.713	0.287
E10 Insulin-dependent diabetes mellitus	0.713	0.287
B99-B99 Other infectious diseases	0.712	0.288
B90-B94 Sequelae of infectious and parasitic diseases	0.712	0.288
B85-B89 Pediculosis, acariasis and other infestations	0.712	0.288
B65-B83 Helminthiases	0.712	0.288
B50-B64 Protozoal diseases	0.712	0.288
B20-B24 Human immunodeficiency virus [HIV] disease	0.712	0.288
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.712	0.288
A80-A89 Viral infections of the central nervous system	0.712	0.288
A75-A79 Rickettsioses	0.712	0.288
A70-A74 Other diseases caused by chlamydiae	0.712	0.288
A65-A69 Other spirochaetal diseases	0.712	0.288
A50-A64 Infections with a predominantly sexual mode of transmission	0.712	0.288
A20-A28 Certain zoonotic bacterial diseases	0.712	0.288
A15-A19 Tuberculosis	0.712	0.288
S62 Fracture at wrist and hand level	0.708	0.292
R95-R99 Ill-defined and unknown causes of mortality	0.703	0.296
T15-T19 Effects of foreign body entering through natural orifice	0.703	0.297
R54 Senility	0.703	0.297
S80 Superficial injury of lower leg	0.703	0.297
T39.1 4-Aminophenol derivatives	0.703	0.297
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.702	0.298
H55-H59 Other disorders of eye and adnexa	0.700	0.300
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.700	0.300
S22 Fracture of rib(s), sternum and thoracic spine	0.699	0.301
D60-D64 Aplastic and other anaemias	0.699	0.301
T66-T78 Other and unspecified effects of external causes	0.697	0.302
H10-H13 Disorders of conjunctiva	0.697	0.303
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.697	0.303
F32.9 Depressive episode, unspecified	0.695	0.305
S64 Injury of nerves at wrist and hand level	0.695	0.305
G57.6 Lesion of plantar nerve	0.694	0.306
R68.8 Other specified general symptoms and signs	0.694	0.306
S89 Other and unspecified injuries of lower leg	0.693	0.307
S27 Injury of other and unspecified intrathoracic organs	0.693	0.307
R46 Symptoms and signs involving appearance and behaviour	0.691	0.308
R43 Disturbances of smell and taste	0.691	0.308
G44 Other headache syndromes	0.690	0.310
M84 Disorders of continuity of bone	0.689	0.311
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.687	0.313
R62 Lack of expected normal physiological development	0.687	0.313
R64 Cachexia	0.687	0.313
R58 Haemorrhage, not elsewhere classified	0.687	0.313
G54 Nerve root and plexus disorders	0.686	0.314
G70-G73 Diseases of myoneural junction and muscle	0.685	0.315
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.685	0.315
G00-G09 Inflammatory diseases of the central nervous system	0.685	0.315
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.684	0.316
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.684	0.316
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.684	0.316
T46 Poisoning by agents primarily affecting the cardiovascular system	0.684	0.316
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.684	0.316
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.684	0.316
T41 Poisoning by anaesthetics and therapeutic gases	0.684	0.316
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.684	0.316
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.684	0.316
T36 Poisoning by systemic antibiotics	0.684	0.316
R90 Abnormal findings on diagnostic imaging of central nervous system	0.681	0.319
R92 Abnormal findings on diagnostic imaging of breast	0.681	0.319
G50 Disorders of trigeminal nerve	0.680	0.320
A07 Other protozoal intestinal diseases	0.680	0.320
A06 Amoebiasis	0.680	0.320
A05 Other bacterial foodborne intoxications	0.680	0.320
A03 Shigellosis	0.680	0.320
A02 Other Salmonella infections	0.680	0.320
A01 Typhoid and paratyphoid fevers	0.680	0.320
A00 Cholera	0.680	0.320
A04.8 Other specified bacterial intestinal infections	0.679	0.321
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.676	0.324
F80-F89 Disorders of psychological development	0.676	0.324
F70-F79 Mental retardation	0.676	0.324
F60-F69 Disorders of adult personality and behaviour	0.676	0.324
D64 Other anaemias	0.676	0.324
H53 Visual disturbances	0.674	0.326
R68.0 Hypothermia, not associated with low environmental temperature	0.672	0.328
G55.2 Nerve root and plexus compressions in spondylosis	0.671	0.329
R94.8 Abnormal results of function studies of other organs and systems	0.671	0.329
R94.7 Abnormal results of other endocrine function studies	0.671	0.329
R94.6 Abnormal results of thyroid function studies	0.671	0.329
R94.4 Abnormal results of kidney function studies	0.671	0.329
R94.2 Abnormal results of pulmonary function studies	0.671	0.329
R94.1 Abnormal results of function studies of peripheral nervous system and special senses	0.671	0.329
R94.0 Abnormal results of function studies of central nervous system	0.671	0.329
B48 Other mycoses, not elsewhere classified	0.668	0.332
B47 Mycetoma	0.668	0.332
B46 Zygomycosis	0.668	0.332
B45 Cryptococcosis	0.668	0.332
B44 Aspergillosis	0.668	0.332
B43 Chromomycosis and phaeomycotic abscess	0.668	0.332
B42 Sporotrichosis	0.668	0.332
B41 Paracoccidioidomycosis	0.668	0.332
B40 Blastomycosis	0.668	0.332
B39 Histoplasmosis	0.668	0.332
B38 Coccidioidomycosis	0.668	0.332
B36 Other superficial mycoses	0.668	0.332
B35 Dermatophytosis	0.668	0.332
B49 Unspecified mycosis	0.668	0.332
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.666	0.334
G45.3 Amaurosis fugax	0.666	0.334
T87 Complications peculiar to reattachment and amputation	0.664	0.336
T86 Failure and rejection of transplanted organs and tissues	0.664	0.336
T80 Complications following infusion, transfusion and therapeutic injection	0.664	0.336
M00-M03 Infectious arthropathies	0.663	0.337
T65 Toxic effect of other and unspecified substances	0.660	0.340
T63 Toxic effect of contact with venomous animals	0.660	0.340
T62 Toxic effect of other noxious substances eaten as food	0.660	0.340
T61 Toxic effect of noxious substances eaten as seafood	0.660	0.340
T60 Toxic effect of pesticides	0.660	0.340
T59 Toxic effect of other gases, fumes and vapours	0.660	0.340
T57 Toxic effect of other inorganic substances	0.660	0.340
T56 Toxic effect of metals	0.660	0.340
T54 Toxic effect of corrosive substances	0.660	0.340
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.660	0.340
T52 Toxic effect of organic solvents	0.660	0.340
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.660	0.340
T58 Toxic effect of carbon monoxide	0.660	0.340
T55 Toxic effect of soaps and detergents	0.660	0.340
S69 Other and unspecified injuries of wrist and hand	0.660	0.340
S67 Crushing injury of wrist and hand	0.660	0.340
S65 Injury of blood vessels at wrist and hand level	0.660	0.340
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.660	0.340
Chapter X Diseases of the respiratory system	0.660	0.340
A04.5 Campylobacter enteritis	0.660	0.340
D64.9 Anaemia, unspecified	0.660	0.340
S81.8 Open wound of other parts of lower leg	0.657	0.343
S68 Traumatic amputation of wrist and hand	0.655	0.345
S88 Traumatic amputation of lower leg	0.654	0.346
S87 Crushing injury of lower leg	0.654	0.346
S86 Injury of muscle and tendon at lower leg level	0.654	0.346
S85 Injury of blood vessels at lower leg level	0.654	0.346
S84 Injury of nerves at lower leg level	0.654	0.346
F32.1 Moderate depressive episode	0.653	0.347
T40.2 Other opioids	0.653	0.347
R94.3 Abnormal results of cardiovascular function studies	0.652	0.348
G90-G99 Other disorders of the nervous system	0.652	0.348
M54 Dorsalgia	0.651	0.349
J09-J18 Influenza and pneumonia	0.649	0.351
G53 Cranial nerve disorders in diseases classified elsewhere	0.649	0.351
G52 Disorders of other cranial nerves	0.649	0.351
H30-H36 Disorders of choroid and retina	0.648	0.352
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.647	0.352
F99 Mental disorder, not otherwise specified	0.646	0.353
G55.0 Nerve root and plexus compressions in neoplastic disease	0.646	0.354
T43.0 Tricyclic and tetracyclic antidepressants	0.646	0.354
S50-S59 Injuries to the elbow and forearm	0.645	0.355
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.645	0.355
B37.3 Candidiasis of vulva and vagina	0.644	0.356
W20-W49 Exposure to inanimate mechanical forces	0.644	0.356
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.642	0.358
M84.1 Nonunion of fracture [pseudarthrosis]	0.641	0.359
F38 Other mood [affective] disorders	0.640	0.360
F34 Persistent mood [affective] disorders	0.640	0.360
F30 Manic episode	0.640	0.360
F39 Unspecified mood [affective] disorder	0.640	0.360
M20-M25 Other joint disorders	0.639	0.361
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.637	0.363
B37.7 Candidal septicaemia	0.637	0.363
B37.6 Candidal endocarditis	0.637	0.363
B37.5 Candidal meningitis	0.637	0.363
B37.4 Candidiasis of other urogenital sites	0.637	0.363
B37.2 Candidiasis of skin and nail	0.637	0.363
B37.1 Pulmonary candidiasis	0.637	0.363
F00-F09 Organic, including symptomatic, mental disorders	0.636	0.363
G46 Vascular syndromes of brain in cerebrovascular diseases	0.635	0.365
G41 Status epilepticus	0.635	0.365
T40.4 Other synthetic narcotics	0.633	0.367
T82.1 Mechanical complication of cardiac electronic device	0.633	0.367
M67 Other disorders of synovium and tendon	0.632	0.368
J18 Pneumonia, organism unspecified	0.632	0.368
Chapter VIII Diseases of the ear and mastoid process	0.631	0.369
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin	0.628	0.371
R41.3 Other amnesia	0.628	0.372
G43.9 Migraine, unspecified	0.628	0.372
E20-E35 Disorders of other endocrine glands	0.628	0.372
S82.2 Fracture of shaft of tibia	0.628	0.372
M91-M94 Chondropathies	0.628	0.372
M60-M63 Disorders of muscles	0.628	0.372
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.627	0.372
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.627	0.372
T82.4 Mechanical complication of vascular dialysis catheter	0.627	0.372
T82.3 Mechanical complication of other vascular grafts	0.627	0.372
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.627	0.372
T82.0 Mechanical complication of heart valve prosthesis	0.627	0.372
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.627	0.373
M87 Osteonecrosis	0.627	0.373
B33 Other viral diseases, not elsewhere classified	0.626	0.374
B30 Viral conjunctivitis	0.626	0.374
B27 Infectious mononucleosis	0.626	0.374
B26 Mumps	0.626	0.374
B25 Cytomegaloviral disease	0.626	0.374
E10.3 With ophthalmic complications	0.626	0.374
F10 Mental and behavioural disorders due to use of alcohol	0.625	0.375
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.624	0.376
Q80-Q89 Other congenital malformations	0.624	0.376
R40 Somnolence, stupor and coma	0.624	0.376
T39.0 Salicylates	0.623	0.377
R73 Elevated blood glucose level	0.623	0.377
T92 Sequelae of injuries of upper limb	0.622	0.378
F32.3 Severe depressive episode with psychotic symptoms	0.621	0.379
T51.9 Alcohol, unspecified	0.620	0.380
T51.8 Other alcohols	0.620	0.380
T51.3 Fusel oil	0.620	0.380
T51.2 2-Propanol	0.620	0.380
T51.1 Methanol	0.620	0.380
R50 Fever of unknown origin	0.618	0.382
A04.9 Bacterial intestinal infection, unspecified	0.618	0.382
A04.6 Enteritis due to Yersinia enterocolitica	0.618	0.382
A04.4 Other intestinal Escherichia coli infections	0.618	0.382
A04.3 Enterohaemorrhagic Escherichia coli infection	0.618	0.382
A04.2 Enteroinvasive Escherichia coli infection	0.618	0.382
A04.1 Enterotoxigenic Escherichia coli infection	0.618	0.382
A04.0 Enteropathogenic Escherichia coli infection	0.618	0.382
G82 Paraplegia and tetraplegia	0.617	0.383
S82.8 Fractures of other parts of lower leg	0.617	0.383
H53.2 Diplopia	0.616	0.384
S29 Other and unspecified injuries of thorax	0.612	0.387
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.612	0.387
S26 Injury of heart	0.612	0.387
S25 Injury of blood vessels of thorax	0.612	0.387
S24 Injury of nerves and spinal cord at thorax level	0.612	0.387
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.612	0.387
S21 Open wound of thorax	0.612	0.387
S20 Superficial injury of thorax	0.612	0.387
S32 Fracture of lumbar spine and pelvis	0.612	0.388
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.612	0.388
S72 Fracture of femur	0.611	0.389
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.611	0.389
R93.8 Abnormal findings on diagnostic imaging of other specified body structures	0.609	0.391
R57.2 Septic shock	0.608	0.392
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.608	0.392
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.608	0.392
T39.4 Antirheumatics, not elsewhere classified	0.608	0.392
T39.2 Pyrazolone derivatives	0.608	0.392
H55 Nystagmus and other irregular eye movements	0.606	0.393
T31 Burns classified according to extent of body surface involved	0.606	0.394
A41 Other septicaemia	0.604	0.396
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.603	0.397
S66.8 Injury of other muscles and tendons at wrist and hand level	0.603	0.397
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.603	0.397
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.603	0.397
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.603	0.397
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.603	0.397
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.603	0.397
R61 Hyperhidrosis	0.602	0.397
F52 Sexual dysfunction, not caused by organic disorder or disease	0.602	0.398
Q20-Q28 Congenital malformations of the circulatory system	0.602	0.398
G58.8 Other specified mononeuropathies	0.601	0.399
Q00-Q07 Congenital malformations of the nervous system	0.601	0.399
G40 Epilepsy	0.599	0.401
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.598	0.402
Q38-Q45 Other congenital malformations of the digestive system	0.598	0.402
S61 Open wound of wrist and hand	0.598	0.402
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere	0.597	0.403
R68.3 Clubbing of fingers	0.595	0.405
R68.2 Dry mouth, unspecified	0.595	0.405
R68.1 Nonspecific symptoms peculiar to infancy	0.595	0.405
Q60-Q64 Congenital malformations of the urinary system	0.595	0.405
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.595	0.405
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.594	0.406
G45.2 Multiple and bilateral precerebral artery syndromes	0.594	0.406
G45.1 Carotid artery syndrome (hemispheric)	0.594	0.406
G45.0 Vertebro-basilar artery syndrome	0.594	0.406
S82.1 Fracture of upper end of tibia	0.594	0.406
F32.2 Severe depressive episode without psychotic symptoms	0.593	0.407
E40-E46 Malnutrition	0.593	0.407
R44.1 Visual hallucinations	0.593	0.407
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.592	0.408
S06 Intracranial injury	0.592	0.408
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.591	0.409
T43.9 Psychotropic drug, unspecified	0.590	0.410
T43.8 Other psychotropic drugs, not elsewhere classified	0.590	0.410
T43.6 Psychostimulants with abuse potential	0.590	0.410
T43.4 Butyrophenone and thioxanthene neuroleptics	0.590	0.410
T43.3 Phenothiazine antipsychotics and neuroleptics	0.590	0.410
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.590	0.410
M23 Internal derangement of knee	0.589	0.411
M88 Paget's disease of bone [osteitis deformans]	0.589	0.411
Y60-Y69 Misadventures to patients during surgical and medical care	0.589	0.411
M45-M49 Spondylopathies	0.589	0.411
J18.1 Lobar pneumonia, unspecified	0.587	0.413
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.587	0.413
G59.0 Diabetic mononeuropathy	0.586	0.414
G20-G26 Extrapyramidal and movement disorders	0.585	0.415
W00-W19 Falls	0.584	0.416
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.584	0.416
E10.9 Without complications	0.582	0.418
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.581	0.419
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.581	0.419
Q50-Q56 Congenital malformations of genital organs	0.581	0.419
Q35-Q37 Cleft lip and cleft palate	0.581	0.419
Q30-Q34 Congenital malformations of the respiratory system	0.581	0.419
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.581	0.419
B18 Chronic viral hepatitis	0.580	0.420
F32.8 Other depressive episodes	0.580	0.420
F32.0 Mild depressive episode	0.580	0.420
S62.6 Fracture of other finger	0.579	0.421
H53.0 Amblyopia ex anopsia	0.579	0.421
E10.2 With renal complications	0.579	0.421
R72 Abnormality of white blood cells, not elsewhere classified	0.579	0.421
R44.3 Hallucinations, unspecified	0.579	0.421
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.579	0.421
H46-H48 Disorders of optic nerve and visual pathways	0.579	0.421
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.579	0.421
G55.3 Nerve root and plexus compressions in other dorsopathies	0.578	0.422
V20-V29 Motorcycle rider injured in transport accident	0.578	0.422
E00-E07 Disorders of thyroid gland	0.577	0.423
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.576	0.424
S37 Injury of urinary and pelvic organs	0.576	0.424
S36 Injury of intra-abdominal organs	0.576	0.424
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.576	0.424
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.576	0.424
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.576	0.424
S31 Open wound of abdomen, lower back and pelvis	0.576	0.424
S30 Superficial injury of abdomen, lower back and pelvis	0.576	0.424
H11 Other disorders of conjunctiva	0.575	0.424
M70-M79 Other soft tissue disorders	0.575	0.425
S27.1 Traumatic haemothorax	0.575	0.425
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.574	0.426
T40.8 Lysergide [LSD]	0.574	0.426
T40.7 Cannabis (derivatives)	0.574	0.426
T40.6 Other and unspecified narcotics	0.574	0.426
T40.5 Cocaine	0.574	0.426
T40.3 Methadone	0.574	0.426
T40.1 Heroin	0.574	0.426
T40.0 Opium	0.574	0.426
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.573	0.427
A08 Viral and other specified intestinal infections	0.573	0.427
Chapter II Neoplasms	0.573	0.427
S82.6 Fracture of lateral malleolus	0.572	0.428
S01 Open wound of head	0.571	0.429
F33.9 Recurrent depressive disorder, unspecified	0.570	0.430
H10 Conjunctivitis	0.570	0.430
G30-G32 Other degenerative diseases of the nervous system	0.569	0.430
X60-X84 Intentional self-harm	0.569	0.430
S81.9 Open wound of lower leg, part unspecified	0.569	0.431
S49 Other and unspecified injuries of shoulder and upper arm	0.568	0.432
S48 Traumatic amputation of shoulder and upper arm	0.568	0.432
S46 Injury of muscle and tendon at shoulder and upper arm level	0.568	0.432
S45 Injury of blood vessels at shoulder and upper arm level	0.568	0.432
S44 Injury of nerves at shoulder and upper arm level	0.568	0.432
S41 Open wound of shoulder and upper arm	0.568	0.432
S40 Superficial injury of shoulder and upper arm	0.568	0.432
S47 Crushing injury of shoulder and upper arm	0.568	0.432
M65 Synovitis and tenosynovitis	0.567	0.433
R47-R49 Symptoms and signs involving speech and voice	0.567	0.433
R85 Abnormal findings in specimens from digestive organs and abdominal cavity	0.567	0.433
R52.2 Other chronic pain	0.566	0.433
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.565	0.435
B34.8 Other viral infections of unspecified site	0.565	0.435
B34.4 Papovirus infection, unspecified	0.565	0.435
B34.3 Parvovirus infection, unspecified	0.565	0.435
B34.2 Coronavirus infection, unspecified	0.565	0.435
B34.1 Enterovirus infection, unspecified	0.565	0.435
B34.0 Adenovirus infection, unspecified	0.565	0.435
S42 Fracture of shoulder and upper arm	0.564	0.436
R52.9 Pain, unspecified	0.563	0.436
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.563	0.437
R52.0 Acute pain	0.563	0.437
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.563	0.437
T88.4 Failed or difficult intubation	0.562	0.438
R74 Abnormal serum enzyme levels	0.562	0.438
Chapter XV Pregnancy, childbirth and the puerperium	0.562	0.438
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.561	0.439
T93 Sequelae of injuries of lower limb	0.561	0.439
S02 Fracture of skull and facial bones	0.561	0.439
G57.9 Mononeuropathy of lower limb, unspecified	0.561	0.439
G57.8 Other mononeuropathies of lower limb	0.561	0.439
G57.5 Tarsal tunnel syndrome	0.561	0.439
G57.4 Lesion of medial popliteal nerve	0.561	0.439
G57.3 Lesion of lateral popliteal nerve	0.561	0.439
G57.2 Lesion of femoral nerve	0.561	0.439
G57.1 Meralgia paraesthetica	0.561	0.439
G57.0 Lesion of sciatic nerve	0.561	0.439
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.560	0.440
G62 Other polyneuropathies	0.560	0.440
T43.2 Other and unspecified antidepressants	0.560	0.440
T50.9 Other and unspecified drugs, medicaments and biological substances	0.560	0.440
T98 Sequelae of other and unspecified effects of external causes	0.559	0.441
T95 Sequelae of burns, corrosions and frostbite	0.559	0.441
T94 Sequelae of injuries involving multiple and unspecified body regions	0.559	0.441
T91 Sequelae of injuries of neck and trunk	0.559	0.441
T90 Sequelae of injuries of head	0.559	0.441
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.559	0.441
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.559	0.441
F31.9 Bipolar affective disorder, unspecified	0.559	0.441
S80.1 Contusion of other and unspecified parts of lower leg	0.558	0.442
T83.1 Mechanical complication of other urinary devices and implants	0.558	0.442
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.558	0.442

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations