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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75587225
log Bayes Factor = 21.2196
Chromosome 5   position 176,166,134  (GRCh37) Explore rs75587225 on Ensembl!
Variant rs75587225 is part of Cluster X0248

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
G40-G47 Episodic and paroxysmal disorders
0.995 0.005 0.000
Chapter IX Diseases of the circulatory system
0.995 0.005 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.994 0.006 0.000
R50-R69 General symptoms and signs
0.993 0.007 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.992 0.008 0.000
D10-D36 Benign neoplasms
0.990 0.010 0.000
Chapter VII Diseases of the eye and adnexa
0.989 0.011 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.988 0.012 0.000
Chapter XI Diseases of the digestive system
0.986 0.014 0.000
Chapter X Diseases of the respiratory system
0.986 0.014 0.000
C15-C26 Malignant neoplasms of digestive organs
0.982 0.018 0.000
G47 Sleep disorders
0.979 0.021 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.976 0.024 0.000
Chapter XX External causes of morbidity and mortality
0.972 0.028 0.000
I83 Varicose veins of lower extremities
0.972 0.028 0.000
D12.5 Sigmoid colon
0.970 0.030 0.000
J30-J39 Other diseases of upper respiratory tract
0.969 0.031 0.000
R59 Enlarged lymph nodes
0.965 0.035 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.959 0.041 0.000
Chapter XXI Factors influencing health status and contact with health services
0.959 0.041 0.000
R30-R39 Symptoms and signs involving the urinary system
0.956 0.044 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.952 0.048 0.000
R33 Retention of urine
0.950 0.050 0.000
K80 Cholelithiasis
0.950 0.050 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.945 0.055 0.000
R15 Faecal incontinence
0.939 0.061 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.938 0.062 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.938 0.062 0.000
H53-H54 Visual disturbances and blindness
0.938 0.062 0.000
G47.3 Sleep apnoea
0.938 0.062 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.935 0.065 0.000
R14 Flatulence and related conditions
0.933 0.067 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.933 0.067 0.000
C64-C68 Malignant neoplasms of urinary tract
0.931 0.069 0.000
K70-K77 Diseases of liver
0.928 0.072 0.000
J90-J94 Other diseases of pleura
0.928 0.072 0.000
I84 Haemorrhoids
0.922 0.078 0.000
I60-I69 Cerebrovascular diseases
0.921 0.079 0.000
R60 Oedema, not elsewhere classified
0.920 0.080 0.000
M70-M79 Other soft tissue disorders
0.915 0.085 0.000
R59.0 Localised enlarged lymph nodes
0.914 0.086 0.000
G40 Epilepsy
0.913 0.087 0.000
C15 Malignant neoplasm of oesophagus
0.913 0.087 0.000
W00-W19 Falls
0.913 0.087 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.912 0.088 0.000
Chapter I Certain infectious and parasitic diseases
0.903 0.097 0.000
I84.6 Residual haemorrhoidal skin tags
0.903 0.097 0.000
G47.9 Sleep disorder, unspecified
0.903 0.097 0.000
J34 Other disorders of nose and nasal sinuses
0.902 0.098 0.000
R53 Malaise and fatigue
0.902 0.098 0.000
R17 Unspecified jaundice
0.899 0.101 0.000
Chapter XIV Diseases of the genitourinary system
0.895 0.105 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.893 0.107 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.887 0.113 0.000
K80.1 Calculus of gallbladder with other cholecystitis
0.887 0.113 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.886 0.114 0.000
J90 Pleural effusion, not elsewhere classified
0.885 0.115 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.883 0.117 0.000
S40-S49 Injuries to the shoulder and upper arm
0.880 0.120 0.000
C67 Malignant neoplasm of bladder
0.879 0.121 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.875 0.125 0.000
M20-M25 Other joint disorders
0.874 0.126 0.000
K81 Cholecystitis
0.873 0.127 0.000
H54 Blindness and low vision
0.873 0.127 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.872 0.128 0.000
H25-H28 Disorders of lens
0.871 0.129 0.000
M05-M14 Inflammatory polyarthropathies
0.870 0.130 0.000
M80-M85 Disorders of bone density and structure
0.869 0.131 0.000
T92 Sequelae of injuries of upper limb
0.869 0.131 0.000
J09-J18 Influenza and pneumonia
0.869 0.131 0.000
R60.0 Localised oedema
0.867 0.133 0.000
H55-H59 Other disorders of eye and adnexa
0.866 0.134 0.000
K35-K38 Diseases of appendix
0.865 0.135 0.000
I84.9 Unspecified haemorrhoids without complication
0.865 0.135 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.864 0.136 0.000
K83 Other diseases of biliary tract
0.864 0.136 0.000
N30-N39 Other diseases of urinary system
0.863 0.137 0.000
D12.6 Colon, unspecified
0.862 0.138 0.000
D00-D09 In situ neoplasms
0.862 0.138 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.862 0.138 0.000
R12 Heartburn
0.860 0.140 0.000
R13 Dysphagia
0.859 0.141 0.000
N39 Other disorders of urinary system
0.856 0.144 0.000
J34.2 Deviated nasal septum
0.855 0.145 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.855 0.145 0.000
R19.5 Other fecal abnormalities
0.853 0.147 0.000
S20-S29 Injuries to the thorax
0.850 0.150 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.848 0.152 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.847 0.153 0.000
G40.9 Epilepsy, unspecified
0.845 0.155 0.000
J36 Peritonsillar abscess
0.845 0.155 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.844 0.156 0.000
I63 Cerebral infarction
0.843 0.157 0.000
W19 Unspecified fall
0.840 0.160 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.839 0.161 0.000
R59.9 Enlarged lymph nodes, unspecified
0.839 0.161 0.000
R19.0 Intra-abdominal and pelvic swelling, mass and lump
0.838 0.162 0.000
C15.9 Oesophagus, unspecified
0.837 0.163 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.835 0.165 0.000
D12.8 Rectum
0.832 0.168 0.000
I82 Other venous embolism and thrombosis
0.832 0.168 0.000
I85 Oesophageal varices
0.832 0.168 0.000
D12.3 Transverse colon
0.831 0.169 0.000
D32 Benign neoplasm of meninges
0.831 0.169 0.000
D45 Polycythaemia vera
0.830 0.170 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.826 0.174 0.000
R19.8 Other specified symptoms and signs involving the digestive system and abdomen
0.824 0.176 0.000
R54 Senility
0.823 0.177 0.000
B95-B98 Bacterial, viral and other infectious agents
0.822 0.178 0.000
I05-I09 Chronic rheumatic heart diseases
0.822 0.178 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.819 0.180 0.000
K74 Fibrosis and cirrhosis of liver
0.819 0.181 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.817 0.183 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.816 0.184 0.000
M65-M68 Disorders of synovium and tendon
0.816 0.184 0.000
J38.3 Other diseases of vocal cords
0.814 0.186 0.000
N10-N16 Renal tubulo-interstitial diseases
0.813 0.187 0.000
R10 Abdominal and pelvic pain
0.813 0.187 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.811 0.189 0.000
R61 Hyperhidrosis
0.810 0.190 0.000
C16 Malignant neoplasm of stomach
0.807 0.193 0.000
K50-K52 Noninfective enteritis and colitis
0.806 0.193 0.000
R56 Convulsions, not elsewhere classified
0.804 0.195 0.000
H25 Senile cataract
0.803 0.197 0.000
S70-S79 Injuries to the hip and thigh
0.801 0.199 0.000
H10-H13 Disorders of conjunctiva
0.801 0.199 0.000
D36 Benign neoplasm of other and unspecified sites
0.800 0.200 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.799 0.201 0.000
N39.3 Stress incontinence
0.799 0.201 0.000
M79.8 Other specified soft tissue disorders
0.799 0.201 0.000
D10 Benign neoplasm of mouth and pharynx
0.798 0.202 0.000
D12.7 Rectosigmoid junction
0.796 0.204 0.000
S80-S89 Injuries to the knee and lower leg
0.793 0.206 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.793 0.207 0.000
H53 Visual disturbances
0.789 0.211 0.000
Z04 Examination and observation for other reasons
0.789 0.211 0.000
R21 Rash and other nonspecific skin eruption
0.788 0.212 0.000
K72 Hepatic failure, not elsewhere classified
0.788 0.212 0.000
D12.2 Ascending colon
0.785 0.215 0.000
K81.0 Acute cholecystitis
0.785 0.215 0.000
R47-R49 Symptoms and signs involving speech and voice
0.785 0.215 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.783 0.217 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.782 0.218 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.782 0.218 0.000
R57 Shock, not elsewhere classified
0.780 0.220 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.778 0.222 0.000
T90 Sequelae of injuries of head
0.777 0.223 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.777 0.223 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.776 0.224 0.000
M79.6 Pain in limb
0.775 0.225 0.000
D27 Benign neoplasm of ovary
0.774 0.226 0.000
D26 Other benign neoplasms of uterus
0.772 0.227 0.000
N60-N64 Disorders of breast
0.772 0.228 0.000
I83.1 Varicose veins of lower extremities with inflammation
0.772 0.228 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.772 0.228 0.000
T66-T78 Other and unspecified effects of external causes
0.771 0.229 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.771 0.229 0.000
S90-S99 Injuries to the ankle and foot
0.770 0.230 0.000
D30 Benign neoplasm of urinary organs
0.770 0.230 0.000
G44 Other headache syndromes
0.769 0.231 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.769 0.231 0.000
N39.4 Other specified urinary incontinence
0.768 0.232 0.000
M06 Other rheumatoid arthritis
0.768 0.232 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.768 0.232 0.000
Chapter XXII Codes for special purposes
0.766 0.234 0.000
T81 Complications of procedures, not elsewhere classified
0.765 0.235 0.000
G81 Hemiplegia
0.764 0.236 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.764 0.236 0.000
M86-M90 Other osteopathies
0.764 0.236 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.763 0.237 0.000
M81 Osteoporosis without pathological fracture
0.761 0.239 0.000
M79.0 Rheumatism, unspecified
0.761 0.239 0.000
S42 Fracture of shoulder and upper arm
0.760 0.240 0.000
C20 Malignant neoplasm of rectum
0.760 0.240 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.760 0.240 0.000
H54.7 Unspecified visual loss
0.758 0.242 0.000
N13 Obstructive and reflux uropathy
0.758 0.242 0.000
C51-C58 Malignant neoplasms of female genital organs
0.757 0.243 0.000
K75 Other inflammatory liver diseases
0.755 0.245 0.000
S50-S59 Injuries to the elbow and forearm
0.755 0.245 0.000
M31 Other necrotising vasculopathies
0.755 0.245 0.000
K83.0 Cholangitis
0.754 0.246 0.000
S10-S19 Injuries to the neck
0.754 0.246 0.000
C25 Malignant neoplasm of pancreas
0.752 0.248 0.000
K35 Acute appendicitis
0.752 0.248 0.000
Z12 Special screening examination for neoplasms
0.752 0.248 0.000
J35 Chronic diseases of tonsils and adenoids
0.750 0.250 0.000
C67.9 Bladder, unspecified
0.750 0.250 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.750 0.250 0.000
T86 Failure and rejection of transplanted organs and tissues
0.748 0.252 0.000
J32 Chronic sinusitis
0.747 0.253 0.000
I67 Other cerebrovascular diseases
0.746 0.254 0.000
C81 Hodgkin's disease
0.745 0.255 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.745 0.255 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.744 0.256 0.000
C15.5 Lower third of oesophagus
0.744 0.256 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.743 0.257 0.000
J18 Pneumonia, organism unspecified
0.742 0.258 0.000
J30 Vasomotor and allergic rhinitis
0.742 0.258 0.000
R68 Other general symptoms and signs
0.741 0.258 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.741 0.259 0.000
R59.1 Generalised enlarged lymph nodes
0.741 0.259 0.000
Z43 Attention to artificial openings
0.740 0.260 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.740 0.260 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.739 0.261 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.739 0.261 0.000
I69 Sequelae of cerebrovascular disease
0.738 0.262 0.000
K50 Crohn's disease [regional enteritis]
0.738 0.262 0.000
I63.9 Cerebral infarction, unspecified
0.737 0.263 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.736 0.264 0.000
I81 Portal vein thrombosis
0.736 0.264 0.000
R69 Unknown and unspecified causes of morbidity
0.736 0.264 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.735 0.264 0.000
N39.8 Other specified disorders of urinary system
0.735 0.265 0.000
G58 Other mononeuropathies
0.735 0.265 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.735 0.265 0.000
C67.1 Dome of bladder
0.734 0.266 0.000
N20-N23 Urolithiasis
0.734 0.266 0.000
H54.4 Blindness, one eye
0.733 0.267 0.000
K73 Chronic hepatitis, not elsewhere classified
0.732 0.267 0.000
C85.1 B-cell lymphoma, unspecified
0.732 0.268 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.732 0.268 0.000
H55 Nystagmus and other irregular eye movements
0.730 0.270 0.000
Chapter VIII Diseases of the ear and mastoid process
0.730 0.270 0.000
I86 Varicose veins of other sites
0.729 0.271 0.000
W19.2 School, other institution and public administrative area
0.729 0.271 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.729 0.271 0.000
M35 Other systemic involvement of connective tissue
0.729 0.271 0.000
R16.0 Hepatomegaly, not elsewhere classified
0.728 0.272 0.000
K55-K64 Other diseases of intestines
0.728 0.272 0.000
W19.9 Unspecified place
0.727 0.273 0.000
R39 Other symptoms and signs involving the urinary system
0.727 0.273 0.000
S40 Superficial injury of shoulder and upper arm
0.726 0.274 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.726 0.274 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.724 0.276 0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm
0.723 0.277 0.000
K86 Other diseases of pancreas
0.722 0.278 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.722 0.278 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.722 0.278 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.721 0.279 0.000
M71 Other bursopathies
0.721 0.279 0.000
K74.6 Other and unspecified cirrhosis of liver
0.721 0.279 0.000
N39.0 Urinary tract infection, site not specified
0.721 0.279 0.000
R30 Pain associated with micturition
0.720 0.280 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.720 0.280 0.000
I82.8 Embolism and thrombosis of other specified veins
0.718 0.282 0.000
D34 Benign neoplasm of thyroid gland
0.718 0.282 0.000
G90-G99 Other disorders of the nervous system
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
G70-G73 Diseases of myoneural junction and muscle
0.716 0.284 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
M40-M43 Deforming dorsopathies
0.714 0.285 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.714 0.286 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.714 0.286 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.714 0.286 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.714 0.286 0.000
G41 Status epilepticus
0.714 0.286 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.714 0.286 0.000
I00-I02 Acute rheumatic fever
0.713 0.287 0.000
M91-M94 Chondropathies
0.712 0.287 0.000
M60-M63 Disorders of muscles
0.712 0.287 0.000
M00-M03 Infectious arthropathies
0.712 0.287 0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb
0.712 0.288 0.000
J34.3 Hypertrophy of nasal turbinates
0.712 0.288 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.712 0.288 0.000
R62 Lack of expected normal physiological development
0.712 0.288 0.000
R64 Cachexia
0.712 0.288 0.000
R58 Haemorrhage, not elsewhere classified
0.712 0.288 0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm
0.712 0.288 0.000
I88 Nonspecific lymphadenitis
0.711 0.289 0.000
I87 Other disorders of veins
0.711 0.289 0.000
C01 Malignant neoplasm of base of tongue
0.711 0.289 0.000
Z13 Special screening examination for other diseases and disorders
0.711 0.289 0.000
Y60.0 During surgical operation
0.711 0.289 0.000
J93 Pneumothorax
0.710 0.290 0.000
S27 Injury of other and unspecified intrathoracic organs
0.710 0.290 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.709 0.290 0.000
D31 Benign neoplasm of eye and adnexa
0.709 0.290 0.000
D29 Benign neoplasm of male genital organs
0.709 0.290 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.709 0.290 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.709 0.290 0.000
D19 Benign neoplasm of mesothelial tissue
0.709 0.290 0.000
D16 Benign neoplasm of bone and articular cartilage
0.709 0.290 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.709 0.290 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.709 0.291 0.000
W06 Fall involving bed
0.709 0.291 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.709 0.291 0.000
W20-W49 Exposure to inanimate mechanical forces
0.708 0.292 0.000
R35 Polyuria
0.708 0.292 0.000
D12.9 Anus and anal canal
0.708 0.292 0.000
D12.1 Appendix
0.708 0.292 0.000
D18 Haemangioma and lymphangioma, any site
0.708 0.292 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.707 0.292 0.000
D32.0 Cerebral meninges
0.707 0.293 0.000
C67.2 Lateral wall of bladder
0.707 0.293 0.000
C92 Myeloid leukaemia
0.706 0.294 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.706 0.294 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.706 0.294 0.000
M45-M49 Spondylopathies
0.706 0.294 0.000
T92.1 Sequelae of fracture of arm
0.705 0.295 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.704 0.296 0.000
C21 Malignant neoplasm of anus and anal canal
0.704 0.296 0.000
C17 Malignant neoplasm of small intestine
0.704 0.296 0.000
C23 Malignant neoplasm of gallbladder
0.704 0.296 0.000
Z51 Other medical care
0.704 0.296 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.703 0.297 0.000
T92.0 Sequelae of open wound of upper limb
0.703 0.297 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.703 0.297 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.702 0.298 0.000
M50-M54 Other dorsopathies
0.702 0.298 0.000
G47.8 Other sleep disorders
0.702 0.298 0.000
G47.4 Narcolepsy and cataplexy
0.702 0.298 0.000
G47.2 Disorders of the sleep-wake schedule
0.702 0.298 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.702 0.298 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.702 0.298 0.000
N25-N29 Other disorders of kidney and ureter
0.702 0.298 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.701 0.299 0.000
T79-T79 Certain early complications of trauma
0.700 0.299 0.000
C67.4 Posterior wall of bladder
0.700 0.300 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.700 0.300 0.000
Y44 Agents primarily affecting blood constituents
0.700 0.300 0.000
M67 Other disorders of synovium and tendon
0.700 0.300 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.699 0.300 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.698 0.302 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.698 0.302 0.000
Y57 Other and unspecified drugs and medicaments
0.698 0.302 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.698 0.302 0.000
M07 Psoriatic and enteropathic arthropathies
0.697 0.303 0.000
C16.9 Stomach, unspecified
0.697 0.303 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.697 0.303 0.000
Y35-Y36 Legal intervention and operations of war
0.697 0.303 0.000
Y10-Y34 Event of undetermined intent
0.697 0.303 0.000
Y00-Y09 Assault
0.697 0.303 0.000
X85-X99 Assault
0.697 0.303 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.697 0.303 0.000
X50-X57 Overexertion, travel and privation
0.697 0.303 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.697 0.303 0.000
X30-X39 Exposure to forces of nature
0.697 0.303 0.000
X20-X29 Contact with venomous animals and plants
0.697 0.303 0.000
X10-X19 Contact with heat and hot substances
0.697 0.303 0.000
X00-X09 Exposure to smoke, fire and flames
0.697 0.303 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.697 0.303 0.000
W75-W84 Other accidental threats to breathing
0.697 0.303 0.000
W65-W74 Accidental drowning and submersion
0.697 0.303 0.000
W50-W64 Exposure to animate mechanical forces
0.697 0.303 0.000
V98-V99 Other and unspecified transport accidents
0.697 0.303 0.000
V95-V97 Air and space transport accidents
0.697 0.303 0.000
V90-V94 Water transport accidents
0.697 0.303 0.000
V80-V89 Other land transport accidents
0.697 0.303 0.000
V70-V79 Bus occupant injured in transport accident
0.697 0.303 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.697 0.303 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.697 0.303 0.000
V40-V49 Car occupant injured in transport accident
0.697 0.303 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.697 0.303 0.000
V01-V09 Pedestrian injured in transport accident
0.697 0.303 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.697 0.303 0.000
H54.0 Blindness, both eyes
0.696 0.304 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.696 0.304 0.000
C91 Lymphoid leukaemia
0.696 0.304 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.696 0.304 0.000
J37 Chronic laryngitis and laryngotracheitis
0.695 0.305 0.000
I27 Other pulmonary heart diseases
0.695 0.305 0.000
H40-H42 Glaucoma
0.694 0.305 0.000
D05 Carcinoma in situ of breast
0.694 0.306 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.693 0.307 0.000
D12.0 Caecum
0.693 0.307 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.693 0.307 0.000
G81.9 Hemiplegia, unspecified
0.693 0.307 0.000
H25.9 Senile cataract, unspecified
0.691 0.309 0.000
Z45 Adjustment and management of implanted device
0.691 0.309 0.000
A30-A49 Other bacterial diseases
0.691 0.309 0.000
C22.9 Liver, unspecified
0.691 0.309 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.691 0.309 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.690 0.310 0.000
R51 Headache
0.690 0.310 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.690 0.310 0.000
G20-G26 Extrapyramidal and movement disorders
0.689 0.310 0.000
I08 Multiple valve diseases
0.689 0.311 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.689 0.311 0.000
B25-B34 Other viral diseases
0.688 0.312 0.000
R19.6 Halitosis
0.687 0.312 0.000
R19.3 Abdominal rigidity
0.687 0.312 0.000
R19.2 Visible peristalsis
0.687 0.312 0.000
R19.1 Abnormal bowel sounds
0.687 0.312 0.000
K72.9 Hepatic failure, unspecified
0.687 0.313 0.000
N60 Benign mammary dysplasia
0.686 0.314 0.000
R36 Urethral discharge
0.686 0.314 0.000
R34 Anuria and oliguria
0.686 0.314 0.000
M79.60 Pain in limb (Multiple sites)
0.685 0.315 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.685 0.315 0.000
C18 Malignant neoplasm of colon
0.685 0.315 0.000
H25.8 Other senile cataract
0.684 0.316 0.000
M81.9 Osteoporosis, unspecified
0.684 0.316 0.000
K83.1 Obstruction of bile duct
0.684 0.316 0.000
J39 Other diseases of upper respiratory tract
0.683 0.317 0.000
Z46 Fitting and adjustment of other devices
0.683 0.317 0.000
G45.4 Transient global amnesia
0.683 0.317 0.000
H57 Other disorders of eye and adnexa
0.683 0.317 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.683 0.317 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.682 0.318 0.000
C95 Leukaemia of unspecified cell type
0.682 0.318 0.000
C94 Other leukaemias of specified cell type
0.682 0.318 0.000
C93 Monocytic leukaemia
0.682 0.318 0.000
C88 Malignant immunoproliferative diseases
0.682 0.318 0.000
C86 Other specified types of T/NK-cell lymphoma
0.682 0.318 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.682 0.318 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.682 0.318 0.000
R10.2 Pelvic and perineal pain
0.682 0.318 0.000
K80.3 Calculus of bile duct with cholangitis
0.681 0.319 0.000
K80.8 Other cholelithiasis
0.681 0.319 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.681 0.319 0.000
G50 Disorders of trigeminal nerve
0.680 0.320 0.000
M79.66 Pain in limb (Lower leg)
0.679 0.321 0.000
V20-V29 Motorcycle rider injured in transport accident
0.679 0.321 0.000
K37 Unspecified appendicitis
0.679 0.321 0.000
R61.9 Hyperhidrosis, unspecified
0.679 0.321 0.000
H53.8 Other visual disturbances
0.678 0.322 0.000
M21 Other acquired deformities of limbs
0.677 0.322 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.677 0.323 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.677 0.323 0.000
B35-B49 Mycoses
0.676 0.324 0.000
S20 Superficial injury of thorax
0.676 0.324 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.675 0.325 0.000
Z04.1 Examination and observation following transport accident
0.675 0.325 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.675 0.325 0.000
T98 Sequelae of other and unspecified effects of external causes
0.673 0.327 0.000
T95 Sequelae of burns, corrosions and frostbite
0.673 0.327 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.673 0.327 0.000
T91 Sequelae of injuries of neck and trunk
0.673 0.327 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.673 0.327 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.673 0.327 0.000
Z10 Routine general health check-up of defined subpopulation
0.673 0.327 0.000
I60 Subarachnoid haemorrhage
0.672 0.327 0.000
I85.9 Oesophageal varices without bleeding
0.672 0.328 0.000
K50.1 Crohn's disease of large intestine
0.672 0.328 0.000
I63.8 Other cerebral infarction
0.672 0.328 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.671 0.328 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.671 0.329 0.000
R11 Nausea and vomiting
0.671 0.329 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.670 0.330 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.670 0.330 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.670 0.330 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.670 0.330 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.670 0.330 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.670 0.330 0.000
J60-J70 Lung diseases due to external agents
0.670 0.330 0.000
R56.8 Other and unspecified convulsions
0.670 0.330 0.000
D14.1 Larynx
0.669 0.331 0.000
M31.6 Other giant cell arteritis
0.669 0.331 0.000
M10 Gout
0.669 0.331 0.000
T87 Complications peculiar to reattachment and amputation
0.669 0.331 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.669 0.331 0.000
T93 Sequelae of injuries of lower limb
0.668 0.332 0.000
R10.0 Acute abdomen
0.668 0.332 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.668 0.332 0.000
C66 Malignant neoplasm of ureter
0.668 0.332 0.000
C65 Malignant neoplasm of renal pelvis
0.668 0.332 0.000
M24 Other specific joint derangements
0.668 0.332 0.000
M72 Fibroblastic disorders
0.667 0.333 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.667 0.333 0.000
I67.1 Cerebral aneurysm, nonruptured
0.666 0.334 0.000
R60.9 Oedema, unspecified
0.666 0.334 0.000
K77 Liver disorders in diseases classified elsewhere
0.666 0.334 0.000
K71 Toxic liver disease
0.666 0.334 0.000
J94 Other pleural conditions
0.665 0.335 0.000
J91 Pleural effusion in conditions classified elsewhere
0.665 0.335 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.665 0.335 0.000
K81.1 Chronic cholecystitis
0.665 0.335 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.664 0.336 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.664 0.336 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.664 0.336 0.000
H43-H45 Disorders of vitreous body and globe
0.664 0.336 0.000
X60-X84 Intentional self-harm
0.663 0.337 0.000
R39.1 Other difficulties with micturition
0.663 0.337 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.663 0.337 0.000
I85.0 Oesophageal varices with bleeding
0.662 0.338 0.000
R10.4 Other and unspecified abdominal pain
0.662 0.338 0.000
M80 Osteoporosis with pathological fracture
0.662 0.338 0.000
I84.7 Unspecified thrombosed haemorrhoids
0.661 0.339 0.000
I84.3 External thrombosed haemorrhoids
0.661 0.339 0.000
I84.0 Internal thrombosed haemorrhoids
0.661 0.339 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.660 0.340 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.660 0.340 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.660 0.340 0.000
I62 Other nontraumatic intracranial haemorrhage
0.660 0.340 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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