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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75601073
log Bayes Factor = 12.1788
Chromosome 2   position 59,364,237  (GRCh37) Explore rs75601073 on Ensembl!
Variant rs75601073 is part of Cluster X0079

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.999 0.001 0.000
Chapter VI Diseases of the nervous system
0.998 0.002 0.000
A30-A49 Other bacterial diseases
0.996 0.004 0.000
C79 Secondary malignant neoplasm of other sites
0.996 0.004 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.993 0.007 0.000
Chapter X Diseases of the respiratory system
0.992 0.008 0.000
A41 Other septicaemia
0.991 0.009 0.000
Chapter XX External causes of morbidity and mortality
0.986 0.014 0.000
G90-G99 Other disorders of the nervous system
0.985 0.015 0.000
J30-J39 Other diseases of upper respiratory tract
0.983 0.017 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.979 0.021 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.974 0.026 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.973 0.027 0.000
G40-G47 Episodic and paroxysmal disorders
0.972 0.028 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.971 0.029 0.000
E10-E14 Diabetes mellitus
0.959 0.041 0.000
A41.9 Septicaemia, unspecified
0.952 0.048 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.951 0.049 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.951 0.049 0.000
C34 Malignant neoplasm of bronchus and lung
0.950 0.050 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.948 0.052 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.947 0.053 0.000
G40 Epilepsy
0.946 0.054 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.945 0.055 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.944 0.056 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.938 0.062 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.934 0.066 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.934 0.066 0.000
E10 Insulin-dependent diabetes mellitus
0.926 0.074 0.000
J34 Other disorders of nose and nasal sinuses
0.925 0.075 0.000
G93 Other disorders of brain
0.916 0.084 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.916 0.084 0.000
L40-L45 Papulosquamous disorders
0.915 0.085 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.913 0.087 0.000
C44 Other malignant neoplasms of skin
0.906 0.094 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.905 0.095 0.000
M50-M54 Other dorsopathies
0.902 0.098 0.000
D68 Other coagulation defects
0.893 0.107 0.000
B25-B34 Other viral diseases
0.892 0.108 0.000
C34.9 Bronchus or lung, unspecified
0.892 0.108 0.000
C34.1 Upper lobe, bronchus or lung
0.889 0.111 0.000
M70-M79 Other soft tissue disorders
0.888 0.112 0.000
C80 Malignant neoplasm without specification of site
0.888 0.112 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.886 0.114 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.885 0.115 0.000
B95-B98 Bacterial, viral and other infectious agents
0.884 0.116 0.000
D50-D53 Nutritional anaemias
0.881 0.119 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.881 0.119 0.000
B35-B49 Mycoses
0.880 0.120 0.000
J84 Other interstitial pulmonary diseases
0.879 0.121 0.000
L43 Lichen planus
0.877 0.123 0.000
Chapter XIV Diseases of the genitourinary system
0.875 0.125 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.875 0.125 0.000
E10.9 Without complications
0.872 0.128 0.000
J36 Peritonsillar abscess
0.870 0.130 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.869 0.131 0.000
E11 Non-insulin-dependent diabetes mellitus
0.868 0.132 0.000
W20-W49 Exposure to inanimate mechanical forces
0.859 0.141 0.000
A41.8 Other specified septicaemia
0.853 0.147 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.850 0.150 0.000
L43.9 Lichen planus, unspecified
0.850 0.150 0.000
D70 Agranulocytosis
0.848 0.152 0.000
A48 Other bacterial diseases, not elsewhere classified
0.848 0.152 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.842 0.158 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.841 0.159 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.836 0.164 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.834 0.166 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.833 0.167 0.000
E20-E35 Disorders of other endocrine glands
0.833 0.167 0.000
G70-G73 Diseases of myoneural junction and muscle
0.832 0.168 0.000
D68.2 Hereditary deficiency of other clotting factors
0.830 0.170 0.000
V10-V19 Pedal cyclist injured in transport accident
0.830 0.170 0.000
M65-M68 Disorders of synovium and tendon
0.829 0.171 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.825 0.175 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.824 0.176 0.000
M50 Cervical disk disorders
0.822 0.178 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.819 0.181 0.000
C92 Myeloid leukaemia
0.818 0.182 0.000
D75 Other diseases of blood and blood-forming organs
0.816 0.184 0.000
J31.0 Chronic rhinitis
0.815 0.185 0.000
B34 Viral infection of unspecified site
0.815 0.185 0.000
M91-M94 Chondropathies
0.814 0.186 0.000
J60-J70 Lung diseases due to external agents
0.810 0.190 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.809 0.190 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.809 0.191 0.000
Chapter XXII Codes for special purposes
0.809 0.191 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.809 0.191 0.000
C44.4 Skin of scalp and neck
0.808 0.192 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.807 0.193 0.000
G44 Other headache syndromes
0.806 0.194 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.805 0.195 0.000
A80-A89 Viral infections of the central nervous system
0.805 0.195 0.000
C78.0 Secondary malignant neoplasm of lung
0.804 0.196 0.000
C51-C58 Malignant neoplasms of female genital organs
0.803 0.196 0.000
G47 Sleep disorders
0.800 0.200 0.000
M51 Other intervertebral disk disorders
0.795 0.205 0.000
G40.9 Epilepsy, unspecified
0.794 0.206 0.000
M86-M90 Other osteopathies
0.793 0.207 0.000
G93.3 Postviral fatigue syndrome
0.790 0.210 0.000
M80-M85 Disorders of bone density and structure
0.790 0.210 0.000
M79.6 Pain in limb
0.790 0.210 0.000
D69 Purpura and other haemorrhagic conditions
0.789 0.211 0.000
Chapter VIII Diseases of the ear and mastoid process
0.784 0.216 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.783 0.217 0.000
E10.3 With ophthalmic complications
0.783 0.217 0.000
J33 Nasal polyp
0.783 0.217 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.782 0.218 0.000
G93.8 Other specified disorders of brain
0.781 0.219 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.781 0.219 0.000
J09-J18 Influenza and pneumonia
0.781 0.219 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.778 0.222 0.000
M60-M63 Disorders of muscles
0.774 0.226 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.773 0.227 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.772 0.228 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.772 0.228 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.772 0.228 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.772 0.228 0.000
Y52 Agents primarily affecting the cardiovascular system
0.770 0.230 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.769 0.231 0.000
W25 Contact with sharp glass
0.768 0.232 0.000
A49 Bacterial infection of unspecified site
0.768 0.232 0.000
Y40 Systemic antibiotics
0.767 0.233 0.000
J81 Pulmonary oedema
0.766 0.234 0.000
B35 Dermatophytosis
0.766 0.234 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.765 0.235 0.000
D52 Folate deficiency anaemia
0.765 0.235 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.764 0.236 0.000
S80-S89 Injuries to the knee and lower leg
0.764 0.236 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.761 0.239 0.000
J39 Other diseases of upper respiratory tract
0.760 0.240 0.000
B34.9 Viral infection, unspecified
0.760 0.240 0.000
Y44 Agents primarily affecting blood constituents
0.758 0.242 0.000
G95 Other diseases of spinal cord
0.757 0.243 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.756 0.244 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.754 0.245 0.000
D68.9 Coagulation defect, unspecified
0.754 0.246 0.000
N92 Excessive, frequent and irregular menstruation
0.754 0.246 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.753 0.247 0.000
M67 Other disorders of synovium and tendon
0.753 0.247 0.000
J32 Chronic sinusitis
0.751 0.249 0.000
D51 Vitamin B12 deficiency anaemia
0.751 0.249 0.000
G90 Disorders of autonomic nervous system
0.749 0.251 0.000
Y43 Primarily systemic agents
0.749 0.251 0.000
C44.7 Skin of lower limb, including hip
0.749 0.251 0.000
L60-L75 Disorders of skin appendages
0.748 0.252 0.000
N00-N08 Glomerular diseases
0.747 0.253 0.000
G40.8 Other epilepsy
0.745 0.255 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.745 0.255 0.000
C44.2 Skin of ear and external auricular canal
0.743 0.257 0.000
L40 Psoriasis
0.743 0.257 0.000
C43 Malignant melanoma of skin
0.742 0.258 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.741 0.259 0.000
A48.1 Legionnaires' disease
0.741 0.259 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.740 0.259 0.000
C92.0 Acute myeloid leukaemia
0.736 0.264 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.735 0.265 0.000
C44.0 Skin of lip
0.733 0.267 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.733 0.267 0.000
M45-M49 Spondylopathies
0.733 0.267 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.732 0.268 0.000
D00-D09 In situ neoplasms
0.732 0.268 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.731 0.269 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.730 0.270 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.730 0.270 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.729 0.271 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.729 0.271 0.000
W00-W19 Falls
0.728 0.272 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.728 0.272 0.000
E10.5 With peripheral circulatory complications
0.725 0.275 0.000
E23 Hypofunction and other disorders of pituitary gland
0.725 0.275 0.000
E11.9 Without complications
0.725 0.275 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.724 0.276 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.723 0.277 0.000
C15-C26 Malignant neoplasms of digestive organs
0.723 0.277 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.723 0.277 0.000
G20-G26 Extrapyramidal and movement disorders
0.723 0.277 0.000
C54 Malignant neoplasm of corpus uteri
0.722 0.278 0.000
G93.6 Cerebral oedema
0.721 0.279 0.000
M00-M03 Infectious arthropathies
0.721 0.279 0.000
M79.60 Pain in limb (Multiple sites)
0.721 0.279 0.000
M79.0 Rheumatism, unspecified
0.720 0.280 0.000
C71 Malignant neoplasm of brain
0.719 0.281 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.719 0.281 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.719 0.281 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.718 0.281 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
B99-B99 Other infectious diseases
0.717 0.283 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.717 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.717 0.283 0.000
B65-B83 Helminthiases
0.717 0.283 0.000
B50-B64 Protozoal diseases
0.717 0.283 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.717 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.717 0.283 0.000
A75-A79 Rickettsioses
0.717 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.717 0.283 0.000
A65-A69 Other spirochaetal diseases
0.717 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.717 0.283 0.000
A15-A19 Tuberculosis
0.717 0.283 0.000
N17-N19 Renal failure
0.717 0.283 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.716 0.284 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.716 0.284 0.000
C80.9 Malignant neoplasm, unspecified
0.715 0.285 0.000
A44 Bartonellosis
0.714 0.286 0.000
A43 Nocardiosis
0.714 0.286 0.000
A42 Actinomycosis
0.714 0.286 0.000
A40 Streptococcal septicaemia
0.714 0.286 0.000
A39 Meningococcal infection
0.714 0.286 0.000
A37 Whooping cough
0.714 0.286 0.000
A36 Diphtheria
0.714 0.286 0.000
A32 Listeriosis
0.714 0.286 0.000
A31 Infection due to other mycobacteria
0.714 0.286 0.000
A30 Leprosy [Hansen's disease]
0.714 0.286 0.000
A46 Erysipelas
0.714 0.286 0.000
A38 Scarlet fever
0.714 0.286 0.000
A35 Other tetanus
0.714 0.286 0.000
A34 Obstetrical tetanus
0.714 0.286 0.000
A33 Tetanus neonatorum
0.714 0.286 0.000
C79.6 Secondary malignant neoplasm of ovary
0.714 0.286 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.714 0.286 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.714 0.286 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.714 0.286 0.000
C44.5 Skin of trunk
0.713 0.287 0.000
D55-D59 Haemolytic anaemias
0.712 0.288 0.000
S60-S69 Injuries to the wrist and hand
0.711 0.289 0.000
A41.4 Septicaemia due to anaerobes
0.711 0.289 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.711 0.289 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.711 0.289 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.710 0.290 0.000
T79-T79 Certain early complications of trauma
0.709 0.291 0.000
Y35-Y36 Legal intervention and operations of war
0.707 0.293 0.000
Y10-Y34 Event of undetermined intent
0.707 0.293 0.000
Y00-Y09 Assault
0.707 0.293 0.000
X85-X99 Assault
0.707 0.293 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.707 0.293 0.000
X50-X57 Overexertion, travel and privation
0.707 0.293 0.000
X30-X39 Exposure to forces of nature
0.707 0.293 0.000
X20-X29 Contact with venomous animals and plants
0.707 0.293 0.000
X10-X19 Contact with heat and hot substances
0.707 0.293 0.000
X00-X09 Exposure to smoke, fire and flames
0.707 0.293 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.707 0.293 0.000
W75-W84 Other accidental threats to breathing
0.707 0.293 0.000
W65-W74 Accidental drowning and submersion
0.707 0.293 0.000
W50-W64 Exposure to animate mechanical forces
0.707 0.293 0.000
V98-V99 Other and unspecified transport accidents
0.707 0.293 0.000
V95-V97 Air and space transport accidents
0.707 0.293 0.000
V90-V94 Water transport accidents
0.707 0.293 0.000
V80-V89 Other land transport accidents
0.707 0.293 0.000
V70-V79 Bus occupant injured in transport accident
0.707 0.293 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.707 0.293 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.707 0.293 0.000
V40-V49 Car occupant injured in transport accident
0.707 0.293 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.707 0.293 0.000
V20-V29 Motorcycle rider injured in transport accident
0.707 0.293 0.000
V01-V09 Pedestrian injured in transport accident
0.707 0.293 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.706 0.293 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.706 0.293 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.706 0.293 0.000
G92 Toxic encephalopathy
0.706 0.293 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.706 0.293 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.706 0.294 0.000
Y57 Other and unspecified drugs and medicaments
0.705 0.295 0.000
J37 Chronic laryngitis and laryngotracheitis
0.704 0.295 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.704 0.296 0.000
M50.2 Other cervical disk displacement
0.704 0.296 0.000
C81 Hodgkin's disease
0.704 0.296 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.704 0.296 0.000
N60-N64 Disorders of breast
0.703 0.297 0.000
W25.9 Unspecified place
0.703 0.297 0.000
S90-S99 Injuries to the ankle and foot
0.703 0.297 0.000
N72 Inflammatory disease of cervix uteri
0.702 0.298 0.000
J69 Pneumonitis due to solids and liquids
0.702 0.298 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.701 0.299 0.000
D46 Myelodysplastic syndromes
0.701 0.299 0.000
J35 Chronic diseases of tonsils and adenoids
0.700 0.300 0.000
C34.0 Main bronchus
0.700 0.300 0.000
B15-B19 Viral hepatitis
0.700 0.300 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.700 0.300 0.000
C44.6 Skin of upper limb, including shoulder
0.699 0.301 0.000
E11.5 With peripheral circulatory complications
0.699 0.301 0.000
E40-E46 Malnutrition
0.698 0.301 0.000
M79.7 Fibromyalgia
0.698 0.302 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.697 0.303 0.000
G41 Status epilepticus
0.697 0.303 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.696 0.304 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.696 0.304 0.000
C32 Malignant neoplasm of larynx
0.696 0.304 0.000
C31 Malignant neoplasm of accessory sinuses
0.696 0.304 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.696 0.304 0.000
C37 Malignant neoplasm of thymus
0.696 0.304 0.000
C33 Malignant neoplasm of trachea
0.696 0.304 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.696 0.304 0.000
D60-D64 Aplastic and other anaemias
0.696 0.304 0.000
C79.2 Secondary malignant neoplasm of skin
0.693 0.307 0.000
X60-X84 Intentional self-harm
0.691 0.309 0.000
H60-H62 Diseases of external ear
0.691 0.309 0.000
E13 Other specified diabetes mellitus
0.690 0.309 0.000
G43 Migraine
0.690 0.310 0.000
T86 Failure and rejection of transplanted organs and tissues
0.688 0.312 0.000
C78.7 Secondary malignant neoplasm of liver
0.688 0.312 0.000
G44.2 Tension-type headache
0.688 0.312 0.000
E12 Malnutrition-related diabetes mellitus
0.688 0.312 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.687 0.313 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.687 0.313 0.000
D73 Diseases of spleen
0.686 0.314 0.000
T17 Foreign body in respiratory tract
0.685 0.315 0.000
E14 Unspecified diabetes mellitus
0.685 0.315 0.000
S70-S79 Injuries to the hip and thigh
0.685 0.315 0.000
B35.3 Tinea pedis
0.684 0.316 0.000
T66-T78 Other and unspecified effects of external causes
0.684 0.316 0.000
E16 Other disorders of pancreatic internal secretion
0.684 0.316 0.000
T90 Sequelae of injuries of head
0.684 0.316 0.000
S40-S49 Injuries to the shoulder and upper arm
0.683 0.316 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.683 0.317 0.000
N92.3 Ovulation bleeding
0.682 0.318 0.000
L10-L14 Bullous disorders
0.682 0.318 0.000
C34.8 Overlapping lesion of bronchus and lung
0.681 0.319 0.000
C34.2 Middle lobe, bronchus or lung
0.681 0.319 0.000
D52.9 Folate deficiency anaemia, unspecified
0.681 0.319 0.000
T18 Foreign body in alimentary tract
0.681 0.319 0.000
B37 Candidiasis
0.680 0.320 0.000
D67 Hereditary factor IX deficiency
0.679 0.320 0.000
D66 Hereditary factor VIII deficiency
0.679 0.320 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.679 0.320 0.000
T92 Sequelae of injuries of upper limb
0.679 0.321 0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere
0.679 0.321 0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere
0.679 0.321 0.000
N25-N29 Other disorders of kidney and ureter
0.679 0.321 0.000
J40-J47 Chronic lower respiratory diseases
0.678 0.322 0.000
G96 Other disorders of central nervous system
0.678 0.322 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.678 0.322 0.000
G40.5 Special epileptic syndromes
0.678 0.322 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.678 0.322 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.678 0.322 0.000
G72 Other myopathies
0.678 0.322 0.000
Y59 Other and unspecified vaccines and biological substances
0.678 0.322 0.000
Y58 Bacterial vaccines
0.678 0.322 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.678 0.322 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.678 0.322 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.678 0.322 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.678 0.322 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.678 0.322 0.000
Y48 Anaesthetics and therapeutic gases
0.678 0.322 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.678 0.322 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.678 0.322 0.000
M77 Other enthesopathies
0.677 0.323 0.000
C50-C50 Malignant neoplasm of breast
0.677 0.323 0.000
N18 Chronic renal failure
0.677 0.323 0.000
E29 Testicular dysfunction
0.677 0.323 0.000
T33-T35 Frostbite
0.676 0.323 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.676 0.323 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.676 0.323 0.000
T00-T07 Injuries involving multiple body regions
0.676 0.323 0.000
S10-S19 Injuries to the neck
0.676 0.323 0.000
D69.6 Thrombocytopenia, unspecified
0.676 0.324 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.676 0.324 0.000
J00-J06 Acute upper respiratory infections
0.676 0.324 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.675 0.325 0.000
M67.8 Other specified disorders of synovium and tendon
0.675 0.325 0.000
J34.3 Hypertrophy of nasal turbinates
0.673 0.327 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.673 0.327 0.000
J80 Adult respiratory distress syndrome
0.673 0.327 0.000
D45 Polycythaemia vera
0.671 0.329 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.670 0.330 0.000
D74 Methaemoglobinaemia
0.670 0.330 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.670 0.330 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.670 0.330 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.670 0.330 0.000
C95 Leukaemia of unspecified cell type
0.670 0.330 0.000
C94 Other leukaemias of specified cell type
0.670 0.330 0.000
C93 Monocytic leukaemia
0.670 0.330 0.000
C88 Malignant immunoproliferative diseases
0.670 0.330 0.000
C86 Other specified types of T/NK-cell lymphoma
0.670 0.330 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.670 0.330 0.000
N92.1 Excessive and frequent menstruation with irregular cycle
0.670 0.330 0.000
J34.2 Deviated nasal septum
0.669 0.331 0.000
M76 Enthesopathies of lower limb, excluding foot
0.669 0.331 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.669 0.331 0.000
E10.1 With ketoacidosis
0.669 0.331 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.668 0.332 0.000
D75.2 Essential thrombocytosis
0.667 0.333 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.667 0.333 0.000
A87 Viral meningitis
0.665 0.334 0.000
E11.3 With ophthalmic complications
0.665 0.335 0.000
M51.2 Other specified intervertebral disk displacement
0.665 0.335 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.664 0.336 0.000
E10.8 With unspecified complications
0.664 0.336 0.000
E10.7 With multiple complications
0.664 0.336 0.000
E10.6 With other specified complications
0.664 0.336 0.000
E10.2 With renal complications
0.664 0.336 0.000
E10.0 With coma
0.664 0.336 0.000
C54.1 Endometrium
0.664 0.336 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.663 0.337 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.663 0.337 0.000
M92 Other juvenile osteochondrosis
0.662 0.337 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.663 0.337 0.000
J95-J99 Other diseases of the respiratory system
0.662 0.338 0.000
Y85 Sequelae of transport accidents
0.661 0.339 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.661 0.339 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.658 0.342 0.000
D75.1 Secondary polycythaemia
0.658 0.342 0.000
M50.0 Cervical disk disorder with myelopathy
0.657 0.343 0.000
L40.9 Psoriasis, unspecified
0.657 0.343 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.657 0.343 0.000
G93.9 Disorder of brain, unspecified
0.657 0.343 0.000
G93.7 Reye's syndrome
0.657 0.343 0.000
G93.5 Compression of brain
0.657 0.343 0.000
G93.4 Encephalopathy, unspecified
0.657 0.343 0.000
G93.2 Benign intracranial hypertension
0.657 0.343 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.657 0.343 0.000
G93.0 Cerebral cysts
0.657 0.343 0.000
N87 Dysplasia of cervix uteri
0.657 0.343 0.000
C78.2 Secondary malignant neoplasm of pleura
0.657 0.343 0.000
L44 Other papulosquamous disorders
0.656 0.344 0.000
L41 Parapsoriasis
0.656 0.344 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.656 0.344 0.000
L42 Pityriasis rosea
0.656 0.344 0.000
E11.4 With neurological complications
0.656 0.344 0.000
S81 Open wound of lower leg
0.655 0.345 0.000
E65-E68 Obesity and other hyperalimentation
0.653 0.347 0.000
E10.4 With neurological complications
0.653 0.347 0.000
G91 Hydrocephalus
0.651 0.349 0.000
M05-M14 Inflammatory polyarthropathies
0.651 0.349 0.000
N83.2 Other and unspecified ovarian cysts
0.651 0.349 0.000
Chapter V Mental and behavioural disorders
0.651 0.349 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.650 0.350 0.000
C44.8 Overlapping lesion of skin
0.650 0.350 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.649 0.351 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.649 0.351 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.649 0.351 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.649 0.351 0.000
M84 Disorders of continuity of bone
0.648 0.352 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.648 0.352 0.000
G71 Primary disorders of muscles
0.647 0.353 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.647 0.353 0.000
M53 Other dorsopathies, not elsewhere classified
0.647 0.353 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.647 0.353 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.646 0.354 0.000
M79.67 Pain in limb (Ankle and foot)
0.645 0.355 0.000
B44 Aspergillosis
0.645 0.355 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.645 0.355 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.644 0.356 0.000
V18.0 Driver injured in nontraffic accident
0.643 0.357 0.000
D75.9 Disease of blood and blood-forming organs, unspecified
0.642 0.358 0.000
N60 Benign mammary dysplasia
0.642 0.358 0.000
N70 Salpingitis and oophoritis
0.642 0.358 0.000
C91 Lymphoid leukaemia
0.642 0.358 0.000
M50.1 Cervical disk disorder with radiculopathy
0.641 0.359 0.000
D68.6 Other Thrombophilia
0.640 0.360 0.000
D68.5 Primary Thrombophilia
0.640 0.360 0.000
D68.4 Acquired coagulation factor deficiency
0.640 0.360 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.640 0.360 0.000
D68.1 Hereditary factor XI deficiency
0.640 0.360 0.000
D68.0 Von Willebrand's disease
0.640 0.360 0.000
L60 Nail disorders
0.640 0.360 0.000
C51 Malignant neoplasm of vulva
0.640 0.360 0.000
E11.2 With renal complications
0.640 0.360 0.000
B33 Other viral diseases, not elsewhere classified
0.640 0.360 0.000
B30 Viral conjunctivitis
0.640 0.360 0.000
B27 Infectious mononucleosis
0.640 0.360 0.000
B26 Mumps
0.640 0.360 0.000
B25 Cytomegaloviral disease
0.640 0.360 0.000
M70.2 Olecranon bursitis
0.640 0.360 0.000
E23.2 Diabetes insipidus
0.639 0.361 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.639 0.361 0.000
N99-N99 Other disorders of the genitourinary system
0.637 0.363 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.637 0.363 0.000
M40-M43 Deforming dorsopathies
0.636 0.363 0.000
Y54.3 Benzothiadiazine derivatives
0.636 0.364 0.000
N92.0 Excessive and frequent menstruation with regular cycle
0.636 0.364 0.000
J17 Pneumonia in diseases classified elsewhere
0.636 0.364 0.000
J33.9 Nasal polyp, unspecified
0.636 0.364 0.000
N03 Chronic nephritic syndrome
0.635 0.365 0.000
J31.2 Chronic pharyngitis
0.635 0.365 0.000
J31.1 Chronic nasopharyngitis
0.635 0.365 0.000
L57.0 Actinic keratosis
0.634 0.366 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.634 0.366 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.634 0.366 0.000
D80-D89 Certain disorders involving the immune mechanism
0.633 0.367 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.633 0.367 0.000
Y86 Sequelae of other accidents
0.632 0.367 0.000
M93 Other osteochondropathies
0.632 0.367 0.000
D53 Other nutritional anaemias
0.632 0.368 0.000
Y45.0 Opioids and related analgesics
0.631 0.369 0.000
L50-L54 Urticaria and erythema
0.631 0.369 0.000
B48 Other mycoses, not elsewhere classified
0.631 0.369 0.000
B47 Mycetoma
0.631 0.369 0.000
B46 Zygomycosis
0.631 0.369 0.000
B45 Cryptococcosis
0.631 0.369 0.000
B43 Chromomycosis and phaeomycotic abscess
0.631 0.369 0.000
B42 Sporotrichosis
0.631 0.369 0.000
B41 Paracoccidioidomycosis
0.631 0.369 0.000
B40 Blastomycosis
0.631 0.369 0.000
B39 Histoplasmosis
0.631 0.369 0.000
B38 Coccidioidomycosis
0.631 0.369 0.000
B36 Other superficial mycoses
0.631 0.369 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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