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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75621054
log Bayes Factor = 15.8715
Chromosome 1   position 242,378,718  (GRCh37) Explore rs75621054 on Ensembl!
Variant rs75621054 is part of Cluster X0087

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Z92 Personal history of medical treatment
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Z92.3 Personal history of irradiation
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.997 0.003 0.000
Chapter VII Diseases of the eye and adnexa
0.996 0.004 0.000
Chapter XX External causes of morbidity and mortality
0.991 0.009 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.990 0.010 0.000
H25-H28 Disorders of lens
0.990 0.010 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.989 0.011 0.000
H26 Other cataract
0.988 0.012 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.987 0.013 0.000
H26.9 Cataract, unspecified
0.984 0.016 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.980 0.020 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.980 0.020 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.971 0.029 0.000
Z80 Family history of malignant neoplasm
0.966 0.034 0.000
J00-J06 Acute upper respiratory infections
0.962 0.038 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.954 0.046 0.000
D00-D09 In situ neoplasms
0.945 0.055 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.944 0.056 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.941 0.059 0.000
J30-J39 Other diseases of upper respiratory tract
0.941 0.059 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.940 0.060 0.000
Z96 Presence of other functional implants
0.937 0.063 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.935 0.065 0.000
O60-O75 Complications of labour and delivery
0.932 0.068 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.929 0.071 0.000
D05 Carcinoma in situ of breast
0.923 0.077 0.000
Z85 Personal history of malignant neoplasm
0.921 0.079 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.920 0.080 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.918 0.082 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.918 0.082 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.913 0.087 0.000
C15-C26 Malignant neoplasms of digestive organs
0.910 0.090 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.904 0.096 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.898 0.102 0.000
H30-H36 Disorders of choroid and retina
0.897 0.103 0.000
Z92.0 Personal history of contraception
0.895 0.105 0.000
C50-C50 Malignant neoplasm of breast
0.893 0.107 0.000
C77.2 Intra-abdominal lymph nodes
0.893 0.107 0.000
H26.4 After-cataract
0.890 0.110 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.890 0.110 0.000
J95-J99 Other diseases of the respiratory system
0.886 0.114 0.000
Z93 Artificial opening status
0.886 0.114 0.000
D05.1 Intraductal carcinoma in situ
0.886 0.114 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.885 0.115 0.000
R22.1 Localised swelling, mass and lump, neck
0.884 0.116 0.000
R23 Other skin changes
0.883 0.117 0.000
Z51 Other medical care
0.883 0.117 0.000
Z96.0 Presence of urogenital implants
0.883 0.117 0.000
R30-R39 Symptoms and signs involving the urinary system
0.880 0.120 0.000
Z51.1 Chemotherapy session for neoplasm
0.879 0.121 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.873 0.127 0.000
Z89 Acquired absence of limb
0.868 0.132 0.000
H35 Other retinal disorders
0.868 0.132 0.000
H43-H45 Disorders of vitreous body and globe
0.867 0.133 0.000
R39 Other symptoms and signs involving the urinary system
0.866 0.134 0.000
J03 Acute tonsillitis
0.865 0.135 0.000
Chapter IX Diseases of the circulatory system
0.865 0.135 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.864 0.136 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.860 0.140 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.856 0.144 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.854 0.146 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.854 0.146 0.000
Z80.3 Family history of malignant neoplasm of breast
0.853 0.147 0.000
J00 Acute nasopharyngitis [common cold]
0.848 0.152 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.848 0.152 0.000
C18 Malignant neoplasm of colon
0.847 0.153 0.000
C81 Hodgkin's disease
0.846 0.154 0.000
Z80.4 Family history of malignant neoplasm of genital organs
0.841 0.159 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.839 0.161 0.000
Z80.6 Family history of leukaemia
0.837 0.163 0.000
R22.4 Localised swelling, mass and lump, lower limb
0.836 0.164 0.000
J09-J18 Influenza and pneumonia
0.835 0.165 0.000
Y95 Nosocomial condition
0.832 0.168 0.000
H35.3 Degeneration of macula and posterior pole
0.831 0.169 0.000
R39.1 Other difficulties with micturition
0.829 0.171 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.829 0.171 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.828 0.172 0.000
Z96.1 Presence of intraocular lens
0.827 0.173 0.000
Z88.0 Personal history of allergy to penicillin
0.825 0.175 0.000
Z60 Problems related to social environment
0.823 0.177 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.820 0.180 0.000
Chapter XXII Codes for special purposes
0.818 0.182 0.000
C50 Malignant neoplasm of breast
0.817 0.183 0.000
J40-J47 Chronic lower respiratory diseases
0.817 0.183 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.816 0.184 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.814 0.186 0.000
I30-I52 Other forms of heart disease
0.813 0.187 0.000
Chapter I Certain infectious and parasitic diseases
0.807 0.193 0.000
J98 Other respiratory disorders
0.806 0.194 0.000
J33 Nasal polyp
0.801 0.199 0.000
Z85.6 Personal history of leukaemia
0.801 0.199 0.000
Chapter XI Diseases of the digestive system
0.800 0.200 0.000
W50-W64 Exposure to animate mechanical forces
0.799 0.201 0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.797 0.203 0.000
J03.9 Acute tonsillitis, unspecified
0.796 0.204 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.795 0.205 0.000
Y43 Primarily systemic agents
0.794 0.206 0.000
I50 Heart failure
0.793 0.207 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.793 0.207 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.789 0.211 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.788 0.212 0.000
Z45 Adjustment and management of implanted device
0.787 0.213 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.786 0.214 0.000
Z46 Fitting and adjustment of other devices
0.785 0.215 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.785 0.215 0.000
C77.5 Intrapelvic lymph nodes
0.783 0.217 0.000
H55-H59 Other disorders of eye and adnexa
0.783 0.217 0.000
K70-K77 Diseases of liver
0.783 0.217 0.000
J39 Other diseases of upper respiratory tract
0.782 0.218 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.780 0.220 0.000
J02 Acute pharyngitis
0.778 0.222 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.777 0.223 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.777 0.223 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.777 0.223 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.775 0.225 0.000
V40-V49 Car occupant injured in transport accident
0.774 0.225 0.000
C91 Lymphoid leukaemia
0.773 0.227 0.000
J36 Peritonsillar abscess
0.772 0.228 0.000
R22.3 Localised swelling, mass and lump, upper limb
0.772 0.228 0.000
O48 Prolonged pregnancy
0.771 0.229 0.000
J35 Chronic diseases of tonsils and adenoids
0.770 0.230 0.000
R23.8 Other and unspecified skin changes
0.770 0.230 0.000
Y52 Agents primarily affecting the cardiovascular system
0.768 0.232 0.000
C77.8 Lymph nodes of multiple regions
0.767 0.233 0.000
C79 Secondary malignant neoplasm of other sites
0.767 0.233 0.000
C80 Malignant neoplasm without specification of site
0.767 0.233 0.000
Z96.8 Presence of other specified functional implants
0.766 0.234 0.000
K76 Other diseases of liver
0.766 0.234 0.000
I50.1 Left ventricular failure
0.765 0.235 0.000
M45-M49 Spondylopathies
0.764 0.236 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.764 0.236 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.763 0.237 0.000
C85.1 B-cell lymphoma, unspecified
0.762 0.238 0.000
R22.0 Localised swelling, mass and lump, head
0.761 0.238 0.000
H43 Disorders of vitreous body
0.760 0.240 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.760 0.240 0.000
Z98 Other postsurgical states
0.759 0.241 0.000
I45 Other conduction disorders
0.757 0.243 0.000
Z94 Transplanted organ and tissue status
0.757 0.243 0.000
O36 Maternal care for other known or suspected foetal problems
0.757 0.243 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.756 0.244 0.000
C90.2 Plasmacytoma, extramedullary
0.755 0.245 0.000
O66 Other obstructed labour
0.755 0.245 0.000
Z60.2 Living alone
0.755 0.245 0.000
Q60-Q64 Congenital malformations of the urinary system
0.754 0.246 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.752 0.248 0.000
S40-S49 Injuries to the shoulder and upper arm
0.752 0.248 0.000
R40 Somnolence, stupor and coma
0.752 0.248 0.000
Y86 Sequelae of other accidents
0.752 0.248 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.751 0.249 0.000
C60-C63 Malignant neoplasms of male genital organs
0.750 0.250 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.750 0.250 0.000
C50.4 Upper-outer quadrant of breast
0.748 0.252 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.748 0.252 0.000
Z40 Prophylactic surgery
0.748 0.252 0.000
Y40 Systemic antibiotics
0.748 0.252 0.000
C18.0 Caecum
0.747 0.253 0.000
O80-O84 Delivery
0.747 0.253 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.746 0.254 0.000
Z57 Occupational exposure to risk-factors
0.745 0.255 0.000
R47-R49 Symptoms and signs involving speech and voice
0.744 0.256 0.000
R94 Abnormal results of function studies
0.744 0.256 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.744 0.256 0.000
C81.9 Hodgkin's disease, unspecified
0.743 0.257 0.000
M05-M14 Inflammatory polyarthropathies
0.743 0.257 0.000
Z88.5 Personal history of allergy to narcotic agent
0.742 0.258 0.000
A30-A49 Other bacterial diseases
0.741 0.259 0.000
O63 Long labour
0.741 0.259 0.000
Z81 Family history of mental and behavioural disorders
0.740 0.260 0.000
Z48 Other surgical follow-up care
0.740 0.260 0.000
J43 Emphysema
0.738 0.262 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.738 0.262 0.000
Z93.5 Cystostomy status
0.736 0.264 0.000
I35 Nonrheumatic aortic valve disorders
0.736 0.264 0.000
I05-I09 Chronic rheumatic heart diseases
0.736 0.264 0.000
X60-X84 Intentional self-harm
0.735 0.265 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.735 0.265 0.000
E10-E14 Diabetes mellitus
0.734 0.266 0.000
C77.0 Lymph nodes of head, face and neck
0.732 0.268 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.732 0.268 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.730 0.270 0.000
Z45.8 Adjustment and management of other implanted devices
0.728 0.272 0.000
Z92.8 Personal history of other medical treatment
0.728 0.272 0.000
T92 Sequelae of injuries of upper limb
0.726 0.274 0.000
J84 Other interstitial pulmonary diseases
0.726 0.274 0.000
J60-J70 Lung diseases due to external agents
0.725 0.275 0.000
H26.8 Other specified cataract
0.724 0.276 0.000
O62 Abnormalities of forces of labour
0.724 0.276 0.000
M15-M19 Arthrosis
0.724 0.276 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.723 0.276 0.000
S60-S69 Injuries to the wrist and hand
0.723 0.277 0.000
Z93.0 Tracheostomy status
0.723 0.277 0.000
Q80-Q89 Other congenital malformations
0.721 0.279 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.721 0.279 0.000
Y57 Other and unspecified drugs and medicaments
0.720 0.280 0.000
C77.3 Axillary and upper limb lymph nodes
0.720 0.280 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.719 0.281 0.000
O71 Other obstetric trauma
0.719 0.281 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z92.9 Personal history of medical treatment, unspecified
0.717 0.283 0.000
Z92.5 Personal history of rehabilitation measures
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
C18.9 Colon, unspecified
0.716 0.284 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.715 0.285 0.000
J98.4 Other disorders of lung
0.715 0.285 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.715 0.285 0.000
J20-J22 Other acute lower respiratory infections
0.715 0.285 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.712 0.287 0.000
H10-H13 Disorders of conjunctiva
0.712 0.288 0.000
S70-S79 Injuries to the hip and thigh
0.712 0.288 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.712 0.288 0.000
M80-M85 Disorders of bone density and structure
0.711 0.289 0.000
R04 Haemorrhage from respiratory passages
0.711 0.289 0.000
Z89.6 Acquired absence of leg above knee
0.711 0.289 0.000
R21 Rash and other nonspecific skin eruption
0.710 0.290 0.000
C15 Malignant neoplasm of oesophagus
0.710 0.290 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.710 0.290 0.000
Y35-Y36 Legal intervention and operations of war
0.710 0.290 0.000
Y10-Y34 Event of undetermined intent
0.710 0.290 0.000
Y00-Y09 Assault
0.710 0.290 0.000
X85-X99 Assault
0.710 0.290 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.710 0.290 0.000
X50-X57 Overexertion, travel and privation
0.710 0.290 0.000
X30-X39 Exposure to forces of nature
0.710 0.290 0.000
X20-X29 Contact with venomous animals and plants
0.710 0.290 0.000
X10-X19 Contact with heat and hot substances
0.710 0.290 0.000
X00-X09 Exposure to smoke, fire and flames
0.710 0.290 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.710 0.290 0.000
W75-W84 Other accidental threats to breathing
0.710 0.290 0.000
W65-W74 Accidental drowning and submersion
0.710 0.290 0.000
V98-V99 Other and unspecified transport accidents
0.710 0.290 0.000
V95-V97 Air and space transport accidents
0.710 0.290 0.000
V90-V94 Water transport accidents
0.710 0.290 0.000
V80-V89 Other land transport accidents
0.710 0.290 0.000
V70-V79 Bus occupant injured in transport accident
0.710 0.290 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.710 0.290 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.710 0.290 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.710 0.290 0.000
V01-V09 Pedestrian injured in transport accident
0.710 0.290 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.710 0.290 0.000
C95 Leukaemia of unspecified cell type
0.710 0.290 0.000
C94 Other leukaemias of specified cell type
0.710 0.290 0.000
C93 Monocytic leukaemia
0.710 0.290 0.000
C88 Malignant immunoproliferative diseases
0.710 0.290 0.000
C86 Other specified types of T/NK-cell lymphoma
0.710 0.290 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.710 0.290 0.000
Z80.9 Family history of malignant neoplasm, unspecified
0.710 0.290 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.710 0.290 0.000
H27 Other disorders of lens
0.710 0.290 0.000
C50.5 Lower-outer quadrant of breast
0.710 0.290 0.000
Z51.8 Other specified medical care
0.710 0.290 0.000
O85-O92 Complications predominantly related to the puerperium
0.709 0.291 0.000
C92 Myeloid leukaemia
0.709 0.291 0.000
H26.3 Drug-induced cataract
0.709 0.291 0.000
H26.2 Complicated cataract
0.709 0.291 0.000
H26.1 Traumatic cataract
0.709 0.291 0.000
H26.0 Infantile, juvenile and presenile cataract
0.709 0.291 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.708 0.292 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.708 0.292 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.708 0.292 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.707 0.292 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.706 0.294 0.000
D05.0 Lobular carcinoma in situ
0.705 0.295 0.000
E10 Insulin-dependent diabetes mellitus
0.705 0.295 0.000
I77 Other disorders of arteries and arterioles
0.705 0.295 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.704 0.296 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.702 0.297 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.702 0.298 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.702 0.298 0.000
M19 Other arthrosis
0.702 0.298 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.701 0.298 0.000
Z33 Pregnant state, incidental
0.699 0.301 0.000
H35.8 Other specified retinal disorders
0.699 0.301 0.000
Y44 Agents primarily affecting blood constituents
0.698 0.302 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.698 0.302 0.000
C90.0 Multiple myeloma
0.698 0.302 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.698 0.302 0.000
H35.5 Hereditary retinal dystrophy
0.698 0.302 0.000
H31 Other disorders of choroid
0.697 0.303 0.000
T93 Sequelae of injuries of lower limb
0.695 0.305 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.694 0.306 0.000
I45.1 Other and unspecified right bundle-branch block
0.694 0.306 0.000
I50.0 Congestive heart failure
0.694 0.306 0.000
J04 Acute laryngitis and tracheitis
0.693 0.306 0.000
S20-S29 Injuries to the thorax
0.693 0.307 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.693 0.307 0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues
0.693 0.307 0.000
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs
0.693 0.307 0.000
Y43.3 Other antineoplastic drugs
0.693 0.307 0.000
J98.1 Pulmonary collapse
0.691 0.309 0.000
R23.3 Spontaneous ecchymoses
0.691 0.309 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.690 0.310 0.000
J01 Acute sinusitis
0.690 0.310 0.000
J11 Influenza, virus not identified
0.690 0.310 0.000
O16 Unspecified maternal hypertension
0.690 0.310 0.000
K02 Dental caries
0.689 0.311 0.000
O43 Placental disorders
0.689 0.311 0.000
M19.9 Arthrosis, unspecified
0.688 0.312 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.688 0.312 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.688 0.312 0.000
Z54 Convalescence
0.688 0.312 0.000
W00-W19 Falls
0.688 0.312 0.000
M91-M94 Chondropathies
0.687 0.313 0.000
Z46.6 Fitting and adjustment of urinary device
0.687 0.313 0.000
J39.8 Other specified diseases of upper respiratory tract
0.686 0.314 0.000
Z89.4 Acquired absence of foot and ankle
0.686 0.314 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.685 0.314 0.000
R22.2 Localised swelling, mass and lump, trunk
0.685 0.315 0.000
J47 Bronchiectasis
0.685 0.315 0.000
C77.1 Intrathoracic lymph nodes
0.684 0.316 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.684 0.316 0.000
R22.7 Localised swelling, mass and lump, multiple sites
0.684 0.316 0.000
R23.4 Changes in skin texture
0.684 0.316 0.000
V10-V19 Pedal cyclist injured in transport accident
0.683 0.317 0.000
J43.9 Emphysema, unspecified
0.682 0.318 0.000
I31 Other diseases of pericardium
0.682 0.318 0.000
Z01.8 Other specified special examinations
0.682 0.318 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.682 0.318 0.000
Z93.3 Colostomy status
0.680 0.320 0.000
J33.0 Polyp of nasal cavity
0.680 0.320 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.679 0.320 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.677 0.322 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.677 0.322 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.677 0.322 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.677 0.323 0.000
S10-S19 Injuries to the neck
0.677 0.323 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.677 0.323 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.676 0.324 0.000
Z63 Other problems related to primary support group, including family circumstances
0.676 0.324 0.000
Z88.6 Personal history of allergy to analgesic agent
0.676 0.324 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.675 0.324 0.000
J40 Bronchitis, not specified as acute or chronic
0.675 0.325 0.000
D04 Carcinoma in situ of skin
0.675 0.325 0.000
K12 Stomatitis and related lesions
0.675 0.325 0.000
J37 Chronic laryngitis and laryngotracheitis
0.675 0.325 0.000
O30 Multiple gestation
0.674 0.326 0.000
S00-S09 Injuries to the head
0.674 0.326 0.000
O42 Premature rupture of membranes
0.673 0.327 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.673 0.327 0.000
V20-V29 Motorcycle rider injured in transport accident
0.672 0.328 0.000
Z96.9 Presence of functional implant, unspecified
0.672 0.328 0.000
Z96.5 Presence of tooth-root and mandibular implants
0.672 0.328 0.000
Z96.4 Presence of endocrine implants
0.672 0.328 0.000
Z96.3 Presence of artificial larynx
0.672 0.328 0.000
Z96.2 Presence of otological and audiological implants
0.672 0.328 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.672 0.328 0.000
Z80.8 Family history of malignant neoplasm of other organs or systems
0.671 0.329 0.000
M86-M90 Other osteopathies
0.671 0.329 0.000
Y59 Other and unspecified vaccines and biological substances
0.670 0.330 0.000
Y58 Bacterial vaccines
0.670 0.330 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.670 0.330 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.670 0.330 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.670 0.330 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.670 0.330 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.670 0.330 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.670 0.330 0.000
Y48 Anaesthetics and therapeutic gases
0.670 0.330 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.670 0.330 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.670 0.330 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.670 0.330 0.000
R33 Retention of urine
0.670 0.330 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.669 0.330 0.000
O41 Other disorders of amniotic fluid and membranes
0.669 0.331 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.669 0.331 0.000
Z89.5 Acquired absence of leg at or below knee
0.668 0.332 0.000
D06 Carcinoma in situ of cervix uteri
0.668 0.332 0.000
O74 Complications of anaesthesia during labour and delivery
0.668 0.332 0.000
O73 Retained placenta and membranes, without haemorrhage
0.668 0.332 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.668 0.332 0.000
O61 Failed induction of labour
0.668 0.332 0.000
O60 Preterm delivery
0.668 0.332 0.000
C64-C68 Malignant neoplasms of urinary tract
0.667 0.333 0.000
R40.2 Coma, unspecified
0.667 0.333 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.666 0.334 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.666 0.334 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.666 0.334 0.000
C85.0 Lymphosarcoma
0.666 0.334 0.000
L05 Pilonidal cyst
0.666 0.334 0.000
J80 Adult respiratory distress syndrome
0.665 0.335 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.665 0.335 0.000
Z93.2 Ileostomy status
0.663 0.337 0.000
O44 Placenta praevia
0.663 0.337 0.000
Q50-Q56 Congenital malformations of genital organs
0.663 0.337 0.000
Z97 Presence of other devices
0.663 0.337 0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person
0.662 0.338 0.000
Z34 Supervision of normal pregnancy
0.662 0.338 0.000
D05.7 Other carcinoma in situ of breast
0.662 0.338 0.000
J33.8 Other polyp of sinus
0.661 0.338 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.661 0.339 0.000
K08 Other disorders of teeth and supporting structures
0.661 0.339 0.000
C25 Malignant neoplasm of pancreas
0.661 0.339 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.660 0.340 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.660 0.340 0.000
Z93.1 Gastrostomy status
0.660 0.340 0.000
T33-T35 Frostbite
0.659 0.340 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.659 0.340 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.659 0.340 0.000
T00-T07 Injuries involving multiple body regions
0.659 0.340 0.000
L40-L45 Papulosquamous disorders
0.659 0.341 0.000
D09 Carcinoma in situ of other and unspecified sites
0.659 0.341 0.000
I71 Aortic aneurysm and dissection
0.659 0.341 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.658 0.342 0.000
Z65 Problems related to other psychosocial circumstances
0.658 0.342 0.000
Z64 Problems related to certain psychosocial circumstances
0.658 0.342 0.000
Z62 Other problems related to upbringing
0.658 0.342 0.000
Z61 Problems related to negative life events in childhood
0.658 0.342 0.000
Z59 Problems related to housing and economic circumstances
0.658 0.342 0.000
Z58 Problems related to physical environment
0.658 0.342 0.000
Z56 Problems related to employment and unemployment
0.658 0.342 0.000
Z55 Problems related to education and literacy
0.658 0.342 0.000
Z52 Donors of organs and tissues
0.658 0.342 0.000
Z44 Fitting and adjustment of external prosthetic device
0.658 0.342 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.658 0.342 0.000
M48 Other spondylopathies
0.657 0.343 0.000
Z98.1 Arthrodesis status
0.657 0.343 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.656 0.344 0.000
J81 Pulmonary oedema
0.655 0.344 0.000
Y83.6 Removal of other organ (partial) (total)
0.655 0.345 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.655 0.345 0.000
Q35-Q37 Cleft lip and cleft palate
0.655 0.345 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.655 0.345 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.655 0.345 0.000
Q00-Q07 Congenital malformations of the nervous system
0.655 0.345 0.000
E10.9 Without complications
0.655 0.345 0.000
K76.8 Other specified diseases of liver
0.655 0.345 0.000
H44 Disorders of globe
0.654 0.346 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.652 0.347 0.000
C21 Malignant neoplasm of anus and anal canal
0.652 0.347 0.000
C17 Malignant neoplasm of small intestine
0.652 0.347 0.000
C23 Malignant neoplasm of gallbladder
0.652 0.347 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.652 0.348 0.000
T98 Sequelae of other and unspecified effects of external causes
0.652 0.348 0.000
S50-S59 Injuries to the elbow and forearm
0.652 0.348 0.000
J32 Chronic sinusitis
0.651 0.349 0.000
O69.0 Labour and delivery complicated by prolapse of cord
0.651 0.349 0.000
O70 Perineal laceration during delivery
0.651 0.349 0.000
A41 Other septicaemia
0.650 0.350 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.650 0.350 0.000
E14 Unspecified diabetes mellitus
0.650 0.350 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.649 0.350 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.649 0.351 0.000
T79-T79 Certain early complications of trauma
0.649 0.351 0.000
Z42 Follow-up care involving plastic surgery
0.649 0.351 0.000
W20-W49 Exposure to inanimate mechanical forces
0.648 0.352 0.000
C16 Malignant neoplasm of stomach
0.648 0.352 0.000
Z95.2 Presence of prosthetic heart valve
0.648 0.352 0.000
J30 Vasomotor and allergic rhinitis
0.648 0.352 0.000
J34 Other disorders of nose and nasal sinuses
0.647 0.353 0.000
K04 Diseases of pulp and periapical tissues
0.646 0.354 0.000
O72 Postpartum haemorrhage
0.646 0.354 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.646 0.354 0.000
H35.4 Peripheral retinal degeneration
0.646 0.354 0.000
J02.9 Acute pharyngitis, unspecified
0.646 0.354 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.645 0.355 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.644 0.356 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.644 0.356 0.000
Y98 Lifestyle-related condition
0.644 0.356 0.000
Y97 Environmental-pollution-related condition
0.644 0.356 0.000
Y96 Work-related condition
0.644 0.356 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.644 0.356 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.643 0.357 0.000
H30 Chorioretinal inflammation
0.643 0.357 0.000
M05 Seropositive rheumatoid arthritis
0.643 0.357 0.000
M00-M03 Infectious arthropathies
0.642 0.358 0.000
Q61 Cystic kidney disease
0.642 0.358 0.000
C18.7 Sigmoid colon
0.642 0.358 0.000
O36.9 Maternal care for foetal problem, unspecified
0.642 0.358 0.000
J35.0 Chronic tonsillitis
0.641 0.359 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.641 0.359 0.000
R04.0 Epistaxis
0.640 0.360 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.639 0.361 0.000
O45 Premature separation of placenta [abruptio placentae]
0.638 0.362 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.638 0.362 0.000
O33 Maternal care for known or suspected disproportion
0.638 0.362 0.000
O31 Complications specific to multiple gestation
0.638 0.362 0.000
O40 Polyhydramnios
0.638 0.362 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.638 0.362 0.000
C18.2 Ascending colon
0.637 0.362 0.000
Y85 Sequelae of transport accidents
0.637 0.363 0.000
K07 Dentofacial anomalies [including malocclusion]
0.637 0.363 0.000
K13 Other diseases of lip and oral mucosa
0.636 0.364 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.636 0.364 0.000
J96 Respiratory failure, not elsewhere classified
0.635 0.364 0.000
Z93.9 Artificial opening status, unspecified
0.635 0.364 0.000
Z93.8 Other artificial opening status
0.635 0.364 0.000
M60-M63 Disorders of muscles
0.635 0.365 0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.635 0.365 0.000
M40-M43 Deforming dorsopathies
0.634 0.366 0.000
R23.2 Flushing
0.633 0.367 0.000
R23.1 Pallor
0.633 0.367 0.000
R23.0 Cyanosis
0.633 0.367 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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