TreeWAS – Variant ID: rs75654312

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E83.1 Disorders of iron metabolism	0.000	0.000	1.000
K90.0 Coeliac disease	0.000	0.000	1.000
E10 Insulin-dependent diabetes mellitus	0.000	0.666	0.334
E10.9 Without complications	0.000	0.669	0.331
E10.4 With neurological complications	0.000	0.688	0.312
K90 Intestinal malabsorption	0.000	0.692	0.308
E10.5 With peripheral circulatory complications	0.000	0.692	0.308
E10.6 With other specified complications	0.000	0.698	0.302
E10.8 With unspecified complications	0.000	0.718	0.282
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.750	0.250
E10.2 With renal complications	0.000	0.750	0.250
E10.1 With ketoacidosis	0.000	0.753	0.247
E10.7 With multiple complications	0.000	0.760	0.240
E10-E14 Diabetes mellitus	0.000	0.770	0.230
E10.0 With coma	0.000	0.773	0.226
K90.3 Pancreatic steatorrhoea	0.000	0.779	0.221
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.779	0.221
K90.1 Tropical sprue	0.000	0.779	0.221
E10.3 With ophthalmic complications	0.000	0.782	0.218
K90.8 Other intestinal malabsorption	0.000	0.788	0.212
E83 Disorders of mineral metabolism	0.000	0.794	0.205
E13 Other specified diabetes mellitus	0.000	0.805	0.195
E13.9 Without complications	0.000	0.829	0.171
E14 Unspecified diabetes mellitus	0.000	0.830	0.170
E12 Malnutrition-related diabetes mellitus	0.000	0.835	0.165
E14.3 With ophthalmic complications	0.000	0.838	0.162
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.844	0.156
E70-E90 Metabolic disorders	0.000	0.845	0.155
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.852	0.147
E83.8 Other disorders of mineral metabolism	0.000	0.852	0.147
E83.2 Disorders of zinc metabolism	0.000	0.852	0.147
E83.0 Disorders of copper metabolism	0.000	0.852	0.147
E13.8 With unspecified complications	0.000	0.860	0.140
E13.7 With multiple complications	0.000	0.860	0.140
E13.6 With other specified complications	0.000	0.860	0.140
E13.5 With peripheral circulatory complications	0.000	0.860	0.140
E13.4 With neurological complications	0.000	0.860	0.140
E13.2 With renal complications	0.000	0.860	0.140
E13.1 With ketoacidosis	0.000	0.860	0.140
E13.0 With coma	0.000	0.860	0.140
E13.3 With ophthalmic complications	0.000	0.863	0.137
E88 Other metabolic disorders	0.000	0.869	0.131
E40-E46 Malnutrition	0.000	0.870	0.130
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.872	0.127
E14.5 With peripheral circulatory complications	0.000	0.873	0.127
E85 Amyloidosis	0.000	0.874	0.126
E14.7 With multiple complications	0.000	0.878	0.122
E14.6 With other specified complications	0.000	0.878	0.122
E14.2 Withrenal complications	0.000	0.878	0.122
E14.0 With coma	0.000	0.878	0.122
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.881	0.119
E12.9 Without complications	0.000	0.881	0.119
E12.8 With unspecified complications	0.000	0.881	0.119
E12.7 With multiple complications	0.000	0.881	0.119
E12.6 With other specified complications	0.000	0.881	0.119
E12.5 With peripheral circulatory complications	0.000	0.881	0.119
E12.4 With neurological complications	0.000	0.881	0.119
E12.3 With ophthalmic complications	0.000	0.881	0.119
E12.2 With renal complications	0.000	0.881	0.119
E12.1 With ketoacidosis	0.000	0.881	0.119
E12.0 With coma	0.000	0.881	0.119
E14.4 With neurological complications	0.000	0.882	0.118
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.886	0.114
E46 Unspecified protein-energy malnutrition	0.000	0.887	0.113
E84 Cystic fibrosis	0.000	0.888	0.112
E77 Disorders of glycoprotein metabolism	0.000	0.888	0.112
E76 Disorders of glycosaminoglycan metabolism	0.000	0.888	0.112
E72 Other disorders of amino-acid metabolism	0.000	0.888	0.112
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.888	0.112
E70 Disorders of aromatic amino-acid metabolism	0.000	0.888	0.112
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.888	0.112
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.890	0.110
E16 Other disorders of pancreatic internal secretion	0.000	0.892	0.107
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.893	0.107
E85.9 Amyloidosis, unspecified	0.000	0.895	0.105
E65-E68 Obesity and other hyperalimentation	0.000	0.896	0.104
E14.1 With ketoacidosis	0.000	0.896	0.104
K90.9 Intestinal malabsorption, unspecified	0.000	0.898	0.101
E11 Non-insulin-dependent diabetes mellitus	0.000	0.898	0.102
E79 Disorders of purine and pyrimidine metabolism	0.000	0.899	0.101
E14.8 With unspecified complications	0.000	0.899	0.101
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.900	0.100
E88.8 Other specified metabolic disorders	0.000	0.900	0.100
E88.2 Lipomatosis, not elsewhere classified	0.000	0.901	0.099
E16.2 Hypoglycaemia, unspecified	0.000	0.902	0.098
E89.2 Postprocedural hypoparathyroidism	0.000	0.904	0.096
E85.4 Organ-limited amyloidosis	0.000	0.905	0.095
E88.3 Tumour lysis syndrome	0.000	0.905	0.095
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.906	0.094
E45 Retarded development following protein-energy malnutrition	0.000	0.906	0.094
E43 Unspecified severe protein-energy malnutrition	0.000	0.906	0.094
E42 Marasmic kwashiorkor	0.000	0.906	0.094
E41 Nutritional marasmus	0.000	0.906	0.094
E40 Kwashiorkor	0.000	0.906	0.094
E89.0 Postprocedural hypothyroidism	0.000	0.907	0.093
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.908	0.092
E15 Nondiabetic hypoglycaemic coma	0.000	0.908	0.092
E85.8 Other amyloidosis	0.000	0.909	0.090
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.909	0.090
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.909	0.090
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.909	0.090
E89.4 Postprocedural ovarian failure	0.000	0.911	0.089
E83.3 Disorders of phosphorus metabolism	0.000	0.911	0.088
E74 Other disorders of carbohydrate metabolism	0.000	0.912	0.088
E65 Localised adiposity	0.000	0.912	0.088
E88.9 Metabolic disorder, unspecified	0.000	0.912	0.088
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.914	0.085
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.914	0.085
E89.5 Postprocedural testicular hypofunction	0.000	0.914	0.085
E89.1 Postprocedural hypoinsulinaemia	0.000	0.914	0.085
E11.5 With peripheral circulatory complications	0.000	0.915	0.085
E75.5 Other lipid storage disorders	0.000	0.916	0.084
E85.3 Secondary systemic amyloidosis	0.000	0.916	0.084
E80.4 Gilbert's syndrome	0.000	0.916	0.084
E73 Lactose intolerance	0.000	0.918	0.082
E75.6 Lipid storage disorder, unspecified	0.000	0.918	0.082
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.918	0.082
E75.3 Sphingolipidosis, unspecified	0.000	0.918	0.082
E75.2 Other sphingolipidosis	0.000	0.918	0.082
E75.1 Other gangliosidosis	0.000	0.918	0.082
E75.0 GM2 gangliosidosis	0.000	0.918	0.082
E83.4 Disorders of magnesium metabolism	0.000	0.920	0.080
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.920	0.080
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.920	0.080
E70.3 Albinism	0.000	0.920	0.080
E70.2 Disorders of tyrosine metabolism	0.000	0.920	0.080
E70.1 Other hyperphenylalaninaemias	0.000	0.920	0.080
E70.0 Classical phenylketonuria	0.000	0.920	0.080
E71.3 Disorders of fatty-acid metabolism	0.000	0.920	0.080
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.920	0.080
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.920	0.080
E71.0 Maple-syrup-urine disease	0.000	0.920	0.080
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.920	0.080
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.920	0.080
E72.5 Disorders of glycine metabolism	0.000	0.920	0.080
E72.4 Disorders of ornithine metabolism	0.000	0.920	0.080
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.920	0.080
E72.2 Disorders of urea cycle metabolism	0.000	0.920	0.080
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.920	0.080
E72.0 Disorders of amino-acid transport	0.000	0.920	0.080
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.920	0.080
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.920	0.080
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.920	0.080
E76.2 Other mucopolysaccharidoses	0.000	0.920	0.080
E76.1 Mucopolysaccharidosis, type II	0.000	0.920	0.080
E76.0 Mucopolysaccharidosis, type I	0.000	0.920	0.080
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.920	0.080
E77.8 Other disorders of glycoprotein metabolism	0.000	0.920	0.080
E77.1 Defects in glycoprotein degradation	0.000	0.920	0.080
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.920	0.080
E84.9 Cystic fibrosis, unspecified	0.000	0.920	0.080
E84.8 Cystic fibrosis with other manifestations	0.000	0.920	0.080
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.920	0.080
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.920	0.080
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.920	0.080
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.921	0.079
E80.5 Crigler-Najjar syndrome	0.000	0.921	0.079
E80.3 Defects of catalase and peroxydase	0.000	0.921	0.079
E80.1 Porphyria cutanea tarda	0.000	0.921	0.079
E80.0 Hereditary erythropoietic porphyria	0.000	0.921	0.079
E11.0 With coma	0.000	0.922	0.078
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.923	0.077
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.923	0.077
E16.4 Abnormal secretion of gastrin	0.000	0.923	0.077
E16.3 Increased secretion of glucagon	0.000	0.923	0.077
E80.2 Other porphyria	0.000	0.924	0.076
E80.6 Other disorders of bilirubin metabolism	0.000	0.924	0.075
E11.8 With unspecified complications	0.000	0.925	0.075
E67 Other hyperalimentation	0.000	0.925	0.075
E68 Sequelae of hyperalimentation	0.000	0.925	0.075
E11.1 With ketoacidosis	0.000	0.925	0.075
E11.2 With renal complications	0.000	0.926	0.074
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.927	0.073
E11.7 With multiple complications	0.000	0.927	0.073
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.927	0.073
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.927	0.073
E79.1 Lesch-Nyhan syndrome	0.000	0.927	0.073
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.929	0.071
E11.6 With other specified complications	0.000	0.931	0.069
E11.4 With neurological complications	0.000	0.932	0.068
E44.1 Mild protein-energy malnutrition	0.000	0.932	0.067
E44.0 Moderate protein-energy malnutrition	0.000	0.932	0.067
E00-E07 Disorders of thyroid gland	0.000	0.935	0.065
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.936	0.063
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.936	0.063
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.936	0.063
E74.2 Disorders of galactose metabolism	0.000	0.936	0.063
E74.1 Disorders of fructose metabolism	0.000	0.936	0.063
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.938	0.062
E78.4 Other hyperlipidaemia	0.000	0.940	0.060
E73.8 Other lactose intolerance	0.000	0.941	0.059
E73.1 Secondary lactase deficiency	0.000	0.941	0.059
E73.0 Congenital lactase deficiency	0.000	0.941	0.059
E16.1 Other hypoglycaemia	0.000	0.941	0.058
E74.0 Glycogen storage disease	0.000	0.942	0.058
E78.6 Lipoprotein deficiency	0.000	0.945	0.055
E11.3 With ophthalmic complications	0.000	0.945	0.055
E67.8 Other specified hyperalimentation	0.000	0.946	0.054
E67.3 Hypervitaminosis D	0.000	0.946	0.054
E67.2 Megavitamin-B6 syndrome	0.000	0.946	0.054
E67.1 Hypercarotenaemia	0.000	0.946	0.054
E67.0 Hypervitaminosis A	0.000	0.946	0.054
E50-E64 Other nutritional deficiencies	0.000	0.946	0.053
E83.5 Disorders of calcium metabolism	0.000	0.946	0.053
E78.3 Hyperchylomicronaemia	0.000	0.947	0.053
E89.3 Postprocedural hypopituitarism	0.000	0.948	0.052
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.948	0.052
E78.2 Mixed hyperlipidaemia	0.000	0.949	0.051
E07 Other disorders of thyroid	0.000	0.949	0.051
E78.1 Pure hyperglyceridaemia	0.000	0.950	0.050
E14.9 Without complications	0.000	0.951	0.049
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.952	0.048
E87.3 Alkalosis	0.000	0.953	0.047
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.953	0.047
E00 Congenital iodine-deficiency syndrome	0.000	0.953	0.047
E04 Other non-toxic goitre	0.000	0.954	0.046
E06 Thyroiditis	0.000	0.956	0.044
E07.9 Disorder of thyroid, unspecified	0.000	0.957	0.043
E87.0 Hyperosmolality and hypernatraemia	0.000	0.957	0.043
E03 Other hypothyroidism	0.000	0.958	0.042
E04.9 Non-toxic goitre, unspecified	0.000	0.960	0.040
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.961	0.038
E63 Other nutritional deficiencies	0.000	0.961	0.038
E56 Other vitamin deficiencies	0.000	0.961	0.038
E50 Vitamin A deficiency	0.000	0.961	0.038
E60 Dietary zinc deficiency	0.000	0.961	0.038
E59 Dietary selenium deficiency	0.000	0.961	0.038
E54 Ascorbic acid deficiency	0.000	0.961	0.038
E52 Niacin deficiency [pellagra]	0.000	0.961	0.038
E20-E35 Disorders of other endocrine glands	0.000	0.961	0.039
E03.8 Other specified hypothyroidism	0.000	0.962	0.038
E58 Dietary calcium deficiency	0.000	0.962	0.038
E87.7 Fluid overload	0.000	0.962	0.038
E87.4 Mixed disorder of acid-base balance	0.000	0.963	0.037
E66 Obesity	0.000	0.963	0.037
E87.2 Acidosis	0.000	0.963	0.037
E07.1 Dyshormogenetic goitre	0.000	0.963	0.036
E07.0 Hypersecretion of calcitonin	0.000	0.963	0.036
E53 Deficiency of other B group vitamins	0.000	0.964	0.036
E51 Thiamine deficiency	0.000	0.964	0.035
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.964	0.035
E04.0 Non-toxic diffuse goitre	0.000	0.965	0.035
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.966	0.033
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.966	0.033
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.966	0.033
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.966	0.033
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.966	0.033
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.966	0.033
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.966	0.033
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.966	0.033
E04.8 Other specified non-toxic goitre	0.000	0.966	0.033
E06.3 Autoimmune thyroiditis	0.000	0.967	0.033
E07.8 Other specified disorders of thyroid	0.000	0.968	0.032
E06.5 Other chronic thyroiditis	0.000	0.968	0.032
E06.4 Drug-induced thyroiditis	0.000	0.968	0.032
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.968	0.032
E06.1 Subacute thyroiditis	0.000	0.968	0.032
E06.0 Acute thyroiditis	0.000	0.968	0.032
E78.8 Other disorders of lipoprotein metabolism	0.000	0.969	0.031
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.969	0.031
E03.5 Myxoedema coma	0.000	0.969	0.031
E03.4 Atrophy of thyroid (acquired)	0.000	0.969	0.031
E03.3 Postinfectious hypothyroidism	0.000	0.969	0.031
E03.1 Congenital hypothyroidism without goitre	0.000	0.969	0.031
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.969	0.031
E87.5 Hyperkalaemia	0.000	0.969	0.031
E55 Vitamin D deficiency	0.000	0.970	0.030
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.970	0.030
E73.9 Lactose intolerance, unspecified	0.001	0.970	0.029
E20 Hypoparathyroidism	0.000	0.970	0.029
E04.2 Non-toxic multinodular goitre	0.000	0.971	0.029
E28 Ovarian dysfunction	0.000	0.971	0.029
E26 Hyperaldosteronism	0.000	0.971	0.029
E50.9 Vitamin A deficiency, unspecified	0.000	0.972	0.028
E50.8 Other manifestations of vitamin A deficiency	0.000	0.972	0.028
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.972	0.028
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.972	0.028
E50.5 Vitamin A deficiency with night blindness	0.000	0.972	0.028
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.972	0.028
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.972	0.028
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.972	0.028
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.972	0.028
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.972	0.028
E56.9 Vitamin deficiency, unspecified	0.000	0.972	0.028
E56.8 Deficiency of other vitamins	0.000	0.972	0.028
E56.1 Deficiency of vitamin K	0.000	0.972	0.028
E56.0 Deficiency of vitamin E	0.000	0.972	0.028
E63.9 Nutritional deficiency, unspecified	0.000	0.972	0.028
E63.8 Other specified nutritional deficiencies	0.000	0.972	0.028
E63.1 Imbalance of constituents of food intake	0.000	0.972	0.028
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.972	0.028
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.972	0.028
E64.8 Sequelae of other nutritional deficiencies	0.000	0.972	0.028
E64.3 Sequelae of rickets	0.000	0.972	0.028
E64.2 Sequelae of vitamin C deficiency	0.000	0.972	0.028
E64.1 Sequelae of vitamin A deficiency	0.000	0.972	0.028
E64.0 Sequelae of protein-energy malnutrition	0.000	0.972	0.028
E06.9 Thyroiditis, unspecified	0.000	0.972	0.028
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.972	0.028
E32 Diseases of thymus	0.000	0.972	0.028
E31 Polyglandular dysfunction	0.000	0.972	0.028
E30 Disorders of puberty, not elsewhere classified	0.000	0.972	0.028
E25 Adrenogenital disorders	0.000	0.972	0.028
E29 Testicular dysfunction	0.000	0.972	0.028
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.973	0.027
E23 Hypofunction and other disorders of pituitary gland	0.000	0.973	0.027
E66.1 Drug-induced obesity	0.000	0.973	0.027
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.000	0.974	0.026
E53.1 Pyridoxine deficiency	0.000	0.974	0.026
E53.0 Riboflavin deficiency	0.000	0.974	0.026
E28.2 Polycystic ovarian syndrome	0.000	0.974	0.026
E53.9 Vitamin B deficiency, unspecified	0.000	0.974	0.026
E24 Cushing's syndrome	0.000	0.974	0.026
E51.9 Thiamine deficiency, unspecified	0.000	0.974	0.026
E51.8 Other manifestations of thiamine deficiency	0.000	0.974	0.026
E51.1 Beriberi	0.000	0.974	0.026
E66.0 Obesity due to excess calories	0.000	0.975	0.025
E34 Other endocrine disorders	0.000	0.975	0.025
E23.2 Diabetes insipidus	0.000	0.975	0.025
E53.8 Deficiency of other specified B group vitamins	0.000	0.976	0.024
E20.9 Hypoparathyroidism, unspecified	0.000	0.977	0.023
E04.1 Non-toxic single thyroid nodule	0.000	0.977	0.023
E51.2 Wernicke's encephalopathy	0.000	0.977	0.022
E27 Other disorders of adrenal gland	0.000	0.978	0.022
E55.0 Rickets, active	0.000	0.978	0.022
E24.2 Drug-induced Cushing's syndrome	0.000	0.978	0.022
E26.0 Primary hyperaldosteronism	0.000	0.978	0.022
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.978	0.022
E20.8 Other hypoparathyroidism	0.000	0.979	0.021
E20.1 Pseudohypoparathyroidism	0.000	0.979	0.021
E20.0 Idiopathic hypoparathyroidism	0.000	0.979	0.021
E28.9 Ovarian dysfunction, unspecified	0.000	0.979	0.021
E28.8 Other ovarian dysfunction	0.000	0.979	0.021
E28.1 Androgen excess	0.000	0.979	0.021
E28.0 Oestrogen excess	0.000	0.979	0.021
E26.9 Hyperaldosteronism, unspecified	0.000	0.979	0.021
E26.8 Other hyperaldosteronism	0.000	0.979	0.021
E26.1 Secondary hyperaldosteronism	0.000	0.979	0.021
R31 Unspecified haematuria	0.021	0.979	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.979	0.021
E05.8 Other thyrotoxicosis	0.000	0.979	0.021
E61 Deficiency of other nutrient elements	0.001	0.979	0.020
E25.9 Adrenogenital disorder, unspecified	0.000	0.980	0.020
E25.8 Other adrenogenital disorders	0.000	0.980	0.020
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.980	0.020
E30.9 Disorder of puberty, unspecified	0.000	0.980	0.020
E30.8 Other disorders of puberty	0.000	0.980	0.020
E30.1 Precocious puberty	0.000	0.980	0.020
E30.0 Delayed puberty	0.000	0.980	0.020
E31.9 Polyglandular dysfunction, unspecified	0.000	0.980	0.020
E31.8 Other polyglandular dysfunction	0.000	0.980	0.020
E31.1 Polyglandular hyperfunction	0.000	0.980	0.020
E31.0 Autoimmune polyglandular failure	0.000	0.980	0.020
E32.9 Disease of thymus, unspecified	0.000	0.980	0.020
E32.8 Other diseases of thymus	0.000	0.980	0.020
E32.1 Abscess of thymus	0.000	0.980	0.020
E32.0 Persistent hyperplasia of thymus	0.000	0.980	0.020
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.980	0.020
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.980	0.020
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.980	0.020
E29.9 Testicular dysfunction, unspecified	0.000	0.980	0.020
E29.8 Other testicular dysfunction	0.000	0.980	0.020
E29.0 Testicular hyperfunction	0.000	0.980	0.020
K90-K93 Other diseases of the digestive system	0.000	0.980	0.020
E05.5 Thyroid crisis or storm	0.000	0.980	0.020
E05.4 Thyrotoxicosis factitia	0.000	0.980	0.020
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.980	0.020
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.980	0.020
E29.1 Testicular hypofunction	0.000	0.980	0.020
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.980	0.019
E23.1 Drug-induced hypopituitarism	0.000	0.980	0.019
E24.8 Other Cushing's syndrome	0.000	0.981	0.019
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.981	0.019
E24.3 Ectopic ACTH syndrome	0.000	0.981	0.019
E24.1 Nelson's syndrome	0.000	0.981	0.019
E23.7 Disorder of pituitary gland, unspecified	0.000	0.981	0.019
E34.5 Androgen resistance syndrome	0.000	0.982	0.018
E34.4 Constitutional tall stature	0.000	0.982	0.018
E34.3 Short stature, not elsewhere classified	0.000	0.982	0.018
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.982	0.018
E34.1 Other hypersecretion of intestinal hormones	0.000	0.982	0.018
E34.9 Endocrine disorder, unspecified	0.000	0.982	0.018
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.982	0.018
E34.8 Other specified endocrine disorders	0.000	0.982	0.017
E23.6 Other disorders of pituitary gland	0.000	0.983	0.017
E24.0 Pituitary-dependent Cushing's disease	0.000	0.983	0.017
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.983	0.016
E34.0 Carcinoid syndrome	0.000	0.984	0.016
E27.5 Adrenomedullary hyperfunction	0.000	0.984	0.016
E27.0 Other adrenocortical overactivity	0.000	0.984	0.016
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.985	0.015
E61.9 Deficiency of nutrient element, unspecified	0.001	0.985	0.014
E61.8 Deficiency of other specified nutrient elements	0.001	0.985	0.014
E61.7 Deficiency of multiple nutrient elements	0.001	0.985	0.014
E61.6 Vanadium deficiency	0.001	0.985	0.014
E61.5 Molybdenum deficiency	0.001	0.985	0.014
E61.4 Chromium deficiency	0.001	0.985	0.014
E61.3 Manganese deficiency	0.001	0.985	0.014
E61.0 Copper deficiency	0.001	0.985	0.014
E86 Volume depletion	0.000	0.985	0.015
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.985	0.014
C71.2 Temporal lobe	0.014	0.986	0.000
E24.9 Cushing's syndrome, unspecified	0.000	0.986	0.014
C71 Malignant neoplasm of brain	0.014	0.986	0.000
E28.3 Primary ovarian failure	0.000	0.986	0.013
C71.9 Brain, unspecified	0.014	0.986	0.000
E21.3 Hyperparathyroidism, unspecified	0.000	0.986	0.014
E66.9 Obesity, unspecified	0.000	0.986	0.014
E55.9 Vitamin D deficiency, unspecified	0.000	0.986	0.013
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.987	0.013
E21.4 Other specified disorders of parathyroid gland	0.000	0.987	0.013
E21.2 Other hyperparathyroidism	0.000	0.987	0.013
E22 Hyperfunction of pituitary gland	0.000	0.987	0.012
E27.2 Addisonian crisis	0.000	0.988	0.012
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.988	0.012
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.988	0.012
E61.2 Magnesium deficiency	0.001	0.988	0.011
C71.3 Parietal lobe	0.012	0.988	0.000
C71.1 Frontal lobe	0.012	0.988	0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.989	0.010
K93.1 Megacolon in Chagas' disease	0.000	0.989	0.010
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.989	0.010
C71.7 Brain stem	0.011	0.989	0.000
E27.8 Other specified disorders of adrenal gland	0.000	0.989	0.010
C71.6 Cerebellum	0.010	0.990	0.000
C71.5 Cerebral ventricle	0.010	0.990	0.000
C71.0 Cerebrum, except lobes and ventricles	0.010	0.990	0.000
E23.0 Hypopituitarism	0.000	0.990	0.010
C71.8 Overlapping lesion of brain	0.010	0.990	0.000
E27.9 Disorder of adrenal gland, unspecified	0.000	0.990	0.009
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.991	0.009
E22.8 Other hyperfunction of pituitary gland	0.000	0.991	0.009
C71.4 Occipital lobe	0.009	0.991	0.000
E22.1 Hyperprolactinaemia	0.000	0.992	0.008
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.008	0.992	0.000
M41.9 Scoliosis, unspecified	0.008	0.992	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.008	0.992	0.000
E87.6 Hypokalaemia	0.000	0.992	0.007
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.007	0.993	0.000
M41.94 Scoliosis, unspecified (Thoracic region)	0.007	0.993	0.000
G44.2 Tension-type headache	0.007	0.993	0.000
C69 Malignant neoplasm of eye and adnexa	0.007	0.993	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.007	0.993	0.000
E21.0 Primary hyperparathyroidism	0.000	0.993	0.007
C70 Malignant neoplasm of meninges	0.006	0.993	0.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.993	0.007
C69.9 Eye, unspecified	0.006	0.994	0.000
M79.10 Myalgia (Multiple sites)	0.006	0.994	0.000
E22.0 Acromegaly and pituitary gigantism	0.000	0.994	0.006
G31.8 Other specified degenerative diseases of nervous system	0.000	0.994	0.006
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.006	0.994	0.000
N04.9 Unspecified	0.000	0.994	0.006
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.006	0.994	0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.006	0.994	0.000
M41.92 Scoliosis, unspecified (Cervical region)	0.006	0.994	0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.006	0.994	0.000
C69.3 Choroid	0.006	0.994	0.000
E61.1 Iron deficiency	0.001	0.994	0.004
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.006	0.994	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.005	0.995	0.000
C69.8 Overlapping lesion of eye and adnexa	0.005	0.995	0.000
C69.5 Lachrymal gland and duct	0.005	0.995	0.000
C69.4 Ciliary body	0.005	0.995	0.000
C69.2 Retina	0.005	0.995	0.000
C69.1 Cornea	0.005	0.995	0.000
C70.0 Cerebral meninges	0.005	0.995	0.000
C69.6 Orbit	0.005	0.995	0.000
C69.0 Conjunctiva	0.005	0.995	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.995	0.005
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.005	0.995	0.000
G54.9 Nerve root and plexus disorder, unspecified	0.005	0.995	0.000
C70.9 Meninges, unspecified	0.005	0.995	0.000
C70.1 Spinal meninges	0.005	0.995	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.001	0.995	0.004
G31.0 Circumscribed brain atrophy	0.000	0.995	0.005
E66.8 Other obesity	0.000	0.995	0.005
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.995	0.005
C72.9 Central nervous system, unspecified	0.004	0.995	0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.004	0.995	0.000
C72.5 Other and unspecified cranial nerves	0.004	0.995	0.000
C72.4 Acoustic nerve	0.004	0.995	0.000
C72.3 Optic nerve	0.004	0.995	0.000
C72.2 Olfactory nerve	0.004	0.995	0.000
C72.1 Cauda equina	0.004	0.995	0.000
M79.19 Myalgia (Site unspecified)	0.004	0.996	0.000
R52.1 Chronic intractable pain	0.004	0.996	0.000
C72.0 Spinal cord	0.004	0.996	0.000
M79.1 Myalgia	0.004	0.996	0.000
I31.9 Disease of pericardium, unspecified	0.000	0.996	0.004
M41 Scoliosis	0.004	0.996	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.000	0.996	0.004
M22.2 Patellofemoral disorders	0.004	0.996	0.000
M67.8 Other specified disorders of synovium and tendon	0.000	0.996	0.004
K22.8 Other specified diseases of oesophagus	0.004	0.996	0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome	0.004	0.996	0.000
Z86.1 Personal history of infectious and parasitic diseases	0.000	0.996	0.004
G44 Other headache syndromes	0.004	0.996	0.000
A04.7 Enterocolitis due to Clostridium difficile	0.003	0.997	0.000
G44.8 Other specified headache syndromes	0.003	0.997	0.000
M79.15 Myalgia (Pelvic region and thigh)	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations