TreeWAS – Variant ID: rs757210

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D86.9 Sarcoidosis, unspecified	0.005	0.995	0.000
H35.3 Degeneration of macula and posterior pole	0.005	0.995	0.000
D86 Sarcoidosis	0.004	0.996	0.000
N81.2 Incomplete uterovaginal prolapse	0.004	0.996	0.000
H35 Other retinal disorders	0.004	0.996	0.000
D86.8 Sarcoidosis of other and combined sites	0.004	0.996	0.000
H35.8 Other specified retinal disorders	0.004	0.996	0.000
H35.0 Background retinopathy and retinal vascular changes	0.004	0.996	0.000
D86.0 Sarcoidosis of lung	0.004	0.996	0.000
H35.4 Peripheral retinal degeneration	0.004	0.996	0.000
H35.2 Other proliferative retinopathy	0.004	0.996	0.000
D86.3 Sarcoidosis of skin	0.003	0.996	0.000
D80-D89 Certain disorders involving the immune mechanism	0.004	0.996	0.000
D75 Other diseases of blood and blood-forming organs	0.004	0.996	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.004	0.996	0.000
H35.7 Separation of retinal layers	0.003	0.996	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.003	0.997	0.000
D69 Purpura and other haemorrhagic conditions	0.003	0.997	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.003	0.997	0.000
N89.8 Other specified noninflammatory disorders of vagina	0.003	0.997	0.000
H35.1 Retinopathy of prematurity	0.003	0.997	0.000
H35.9 Retinal disorder, unspecified	0.003	0.997	0.000
H35.5 Hereditary retinal dystrophy	0.003	0.997	0.000
D75.2 Essential thrombocytosis	0.003	0.997	0.000
D86.1 Sarcoidosis of lymph nodes	0.003	0.997	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.003	0.997	0.000
N81.4 Uterovaginal prolapse, unspecified	0.003	0.997	0.000
N81 Female genital prolapse	0.003	0.997	0.000
H35.6 Retinal haemorrhage	0.003	0.997	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.003	0.997	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.003	0.997	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.003	0.997	0.000
S52.60 Fracture of lower end of both ulna and radius (closed)	0.003	0.997	0.000
D69.5 Secondary thrombocytopenia	0.003	0.997	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.003	0.997	0.000
N81.3 Complete uterovaginal prolapse	0.003	0.997	0.000
G40.9 Epilepsy, unspecified	0.000	0.997	0.003
D70 Agranulocytosis	0.003	0.997	0.000
D72 Other disorders of white blood cells	0.003	0.997	0.000
D84 Other immunodeficiencies	0.003	0.997	0.000
D83 Common variable immunodeficiency	0.003	0.997	0.000
D82 Immunodeficiency associated with other major defects	0.003	0.997	0.000
D81 Combined immunodeficiencies	0.003	0.997	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.003	0.997	0.000
D75.0 Familial erythrocytosis	0.003	0.997	0.000
D74 Methaemoglobinaemia	0.003	0.997	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.003	0.997	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.003	0.997	0.000
D60-D64 Aplastic and other anaemias	0.003	0.997	0.000
D69.0 Allergic purpura	0.003	0.997	0.000
N81.9 Female genital prolapse, unspecified	0.003	0.997	0.000
D69.6 Thrombocytopenia, unspecified	0.003	0.997	0.000
T81.3 Disruption of operation wound, not elsewhere classified	0.000	0.997	0.003
D80 Immunodeficiency with predominantly antibody defects	0.003	0.997	0.000
D69.9 Haemorrhagic condition, unspecified	0.003	0.997	0.000
D69.8 Other specified haemorrhagic conditions	0.003	0.997	0.000
D69.4 Other primary thrombocytopenia	0.003	0.997	0.000
D69.2 Other nonthrombocytopenic purpura	0.003	0.997	0.000
D69.1 Qualitative platelet defects	0.003	0.997	0.000
N81.5 Vaginal enterocele	0.003	0.997	0.000
D73 Diseases of spleen	0.003	0.997	0.000
N81.1 Cystocele	0.003	0.997	0.000
D75.1 Secondary polycythaemia	0.003	0.997	0.000
L40.5 Arthropathic psoriasis	0.003	0.997	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.002	0.997	0.000
D76.3 Other histiocytosis syndromes	0.003	0.997	0.000
N81.0 Female urethrocele	0.003	0.997	0.000
D66 Hereditary factor VIII deficiency	0.002	0.997	0.000
D55-D59 Haemolytic anaemias	0.003	0.997	0.000
D67 Hereditary factor IX deficiency	0.002	0.997	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.002	0.997	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.003	0.997	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.002	0.997	0.000
D61 Other aplastic anaemias	0.002	0.997	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.002	0.997	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
D63.0 Anaemia in neoplastic disease	0.002	0.997	0.000
N92.0 Excessive and frequent menstruation with regular cycle	0.003	0.997	0.000
M07.3 Other psoriatic arthropathies	0.002	0.998	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.002	0.998	0.000
D76.2 Haemophagocytic syndrome, infection-associated	0.002	0.998	0.000
D76.1 Haemophagocytic lymphohistiocytosis	0.002	0.998	0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.002	0.998	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.002	0.998	0.000
T40.2 Other opioids	0.002	0.998	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.002	0.998	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.002	0.998	0.000
D68 Other coagulation defects	0.002	0.998	0.000
D72.8 Other specified disorders of white blood cells	0.002	0.998	0.000
D61.9 Aplastic anaemia, unspecified	0.002	0.998	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
D50-D53 Nutritional anaemias	0.002	0.998	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.002	0.998	0.000
D72.1 Eosinophilia	0.002	0.998	0.000
D81.9 Combined immunodeficiency, unspecified	0.002	0.998	0.000
D81.8 Other combined immunodeficiencies	0.002	0.998	0.000
D81.7 Major histocompatibility complex class II deficiency	0.002	0.998	0.000
D81.6 Major histocompatibility complex class I deficiency	0.002	0.998	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.002	0.998	0.000
D81.4 Nezelof's syndrome	0.002	0.998	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.002	0.998	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.002	0.998	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.002	0.998	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.002	0.998	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.002	0.998	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.002	0.998	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.002	0.998	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.002	0.998	0.000
D82.2 Immunodeficiency with short-limbed stature	0.002	0.998	0.000
D82.1 Di George's syndrome	0.002	0.998	0.000
D82.0 Wiskott-Aldrich syndrome	0.002	0.998	0.000
D83.9 Common variable immunodeficiency, unspecified	0.002	0.998	0.000
D83.8 Other common variable immunodeficiencies	0.002	0.998	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.002	0.998	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.002	0.998	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.002	0.998	0.000
D84.9 Immunodeficiency, unspecified	0.002	0.998	0.000
D84.8 Other specified immunodeficiencies	0.002	0.998	0.000
D84.1 Defects in the complement system	0.002	0.998	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.002	0.998	0.000
D72.9 Disorder of white blood cells, unspecified	0.002	0.998	0.000
D72.0 Genetic anomalies of leukocytes	0.002	0.998	0.000
L40.9 Psoriasis, unspecified	0.002	0.998	0.000
D74.9 Methaemoglobinaemia, unspecified	0.002	0.998	0.000
D74.8 Other methaemoglobinaemias	0.002	0.998	0.000
D74.0 Congenital methaemoglobinaemia	0.002	0.998	0.000
D51 Vitamin B12 deficiency anaemia	0.002	0.998	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.002	0.998	0.000
L40 Psoriasis	0.002	0.998	0.000
D73.5 Infarction of spleen	0.002	0.998	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.002	0.998	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.002	0.998	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.002	0.998	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.002	0.998	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.002	0.998	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.002	0.998	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.002	0.998	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.002	0.998	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.002	0.998	0.000
D73.9 Disease of spleen, unspecified	0.002	0.998	0.000
D73.8 Other diseases of spleen	0.002	0.998	0.000
D73.4 Cyst of spleen	0.002	0.998	0.000
D73.3 Abscess of spleen	0.002	0.998	0.000
D73.2 Chronic congestive splenomegaly	0.002	0.998	0.000
D73.1 Hypersplenism	0.002	0.998	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.002	0.998	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.002	0.998	0.000
D89.3 Immune reconstitution syndrome	0.002	0.998	0.000
D89.1 Cryoglobulinaemia	0.002	0.998	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.002	0.998	0.000
D59 Acquired haemolytic anaemia	0.002	0.998	0.000
D62 Acute posthaemorrhagic anaemia	0.002	0.998	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.002	0.998	0.000
D73.0 Hyposplenism	0.002	0.998	0.000
N81.8 Other female genital prolapse	0.002	0.998	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.002	0.998	0.000
D57 Sickle-cell disorders	0.002	0.998	0.000
D56 Thalassaemia	0.002	0.998	0.000
D55 Anaemia due to enzyme disorders	0.002	0.998	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.002	0.998	0.000
D63.1 Anaemia in other chronic diseases classified elsewhere	0.002	0.998	0.000
T43.2 Other and unspecified antidepressants	0.002	0.998	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.002	0.998	0.000
D58 Other hereditary haemolytic anaemias	0.002	0.998	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.002	0.998	0.000
D61.8 Other specified aplastic anaemias	0.002	0.998	0.000
D61.3 Idiopathic aplastic anaemia	0.002	0.998	0.000
D61.2 Aplastic anaemia due to other external agents	0.002	0.998	0.000
D61.1 Drug-induced aplastic anaemia	0.002	0.998	0.000
D61.0 Constitutional aplastic anaemia	0.002	0.998	0.000
T40.4 Other synthetic narcotics	0.002	0.998	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.002	0.998	0.000
S52.6 Fracture of lower end of both ulna and radius	0.002	0.998	0.000
T43.9 Psychotropic drug, unspecified	0.002	0.998	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
T43.6 Psychostimulants with abuse potential	0.002	0.998	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.998	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.998	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
H33 Retinal detachments and breaks	0.002	0.998	0.000
M07.38 Other psoriatic arthropathies (Other)	0.002	0.998	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.002	0.998	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.002	0.998	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.002	0.998	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.002	0.998	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.002	0.998	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.002	0.998	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.002	0.998	0.000
D68.9 Coagulation defect, unspecified	0.002	0.998	0.000
H33.3 Retinal breaks without detachment	0.002	0.998	0.000
T40.6 Other and unspecified narcotics	0.002	0.998	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.002	0.998	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.002	0.998	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.002	0.998	0.000
T39.1 4-Aminophenol derivatives	0.002	0.998	0.000
T85.4 Mechanical complication of breast prosthesis and implant	0.000	0.998	0.002
G40 Epilepsy	0.000	0.998	0.002
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.002	0.998	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.002	0.998	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.002	0.998	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.002	0.998	0.000
T40.8 Lysergide [LSD]	0.002	0.998	0.000
T40.7 Cannabis (derivatives)	0.002	0.998	0.000
T40.5 Cocaine	0.002	0.998	0.000
T40.3 Methadone	0.002	0.998	0.000
T40.1 Heroin	0.002	0.998	0.000
T40.0 Opium	0.002	0.998	0.000
N89 Other noninflammatory disorders of vagina	0.002	0.998	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.002	0.998	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.002	0.998	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
T36 Poisoning by systemic antibiotics	0.002	0.998	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.002	0.998	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.002	0.998	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.002	0.998	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.002	0.998	0.000
T42.3 Barbiturates	0.002	0.998	0.000
T42.2 Succinimides and oxazolidinediones	0.002	0.998	0.000
T42.1 Iminostilbenes	0.002	0.998	0.000
T42.0 Hydantoin derivatives	0.002	0.998	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.998	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.002	0.998	0.000
T46.7 Peripheral vasodilators	0.002	0.998	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.002	0.998	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
T46.1 Calcium-channel blockers	0.002	0.998	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.002	0.998	0.000
D68.4 Acquired coagulation factor deficiency	0.002	0.998	0.000
D68.1 Hereditary factor XI deficiency	0.002	0.998	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.002	0.998	0.000
M10.99 Gout, unspecified (Site unspecified)	0.002	0.998	0.000
L40.8 Other psoriasis	0.002	0.998	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.000	0.998	0.002
D64 Other anaemias	0.002	0.998	0.000
D68.2 Hereditary deficiency of other clotting factors	0.002	0.998	0.000
H33.1 Retinoschisis and retinal cysts	0.002	0.998	0.000
D53 Other nutritional anaemias	0.002	0.998	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.002	0.998	0.000
D68.6 Other Thrombophilia	0.002	0.998	0.000
D68.0 Von Willebrand's disease	0.002	0.998	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.002	0.998	0.000
H30-H36 Disorders of choroid and retina	0.002	0.998	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.002	0.998	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.002	0.998	0.000
D51.2 Transcobalamin II deficiency	0.002	0.998	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.002	0.998	0.000
D60.9 Acquired pure red cell aplasia, unspecified	0.002	0.998	0.000
D60.8 Other acquired pure red cell aplasias	0.002	0.998	0.000
D60.1 Transient acquired pure red cell aplasia	0.002	0.998	0.000
D60.0 Chronic acquired pure red cell aplasia	0.002	0.998	0.000
L40.0 Psoriasis vulgaris	0.002	0.998	0.000
N50.1 Vascular disorders of male genital organs	0.002	0.998	0.000
N81.6 Rectocele	0.002	0.998	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.000	0.998	0.002
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.002	0.998	0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.000	0.998	0.002
L40.4 Guttate psoriasis	0.002	0.998	0.000
L40.3 Pustulosis palmaris et plantaris	0.002	0.998	0.000
L40.2 Acrodermatitis continua	0.002	0.998	0.000
L40.1 Generalised pustular psoriasis	0.002	0.998	0.000
D68.5 Primary Thrombophilia	0.002	0.998	0.000
M07 Psoriatic and enteropathic arthropathies	0.002	0.998	0.000
D68.8 Other specified coagulation defects	0.002	0.998	0.000
I50.0 Congestive heart failure	0.002	0.998	0.000
L03.1 Cellulitis of other parts of limb	0.002	0.998	0.000
M06.0 Seronegative rheumatoid arthritis	0.002	0.998	0.000
N89.9 Noninflammatory disorder of vagina, unspecified	0.002	0.998	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.002	0.998	0.000
D52 Folate deficiency anaemia	0.002	0.998	0.000
D59.1 Other autoimmune haemolytic anaemias	0.002	0.998	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.000	0.998	0.002
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.002	0.998	0.000
T42.4 Benzodiazepines	0.002	0.998	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.002	0.998	0.000
D59.8 Other acquired haemolytic anaemias	0.002	0.998	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.002	0.998	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.002	0.998	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.002	0.998	0.000
D59.3 Haemolytic-uraemic syndrome	0.002	0.998	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.002	0.998	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.002	0.998	0.000
H33.2 Serous retinal detachment	0.002	0.998	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.002	0.998	0.000
Y43 Primarily systemic agents	0.002	0.998	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.002	0.998	0.000
D55.8 Other anaemias due to enzyme disorders	0.002	0.998	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.002	0.998	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.002	0.998	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.002	0.998	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.002	0.998	0.000
D56.9 Thalassaemia, unspecified	0.002	0.998	0.000
D56.8 Other thalassaemias	0.002	0.998	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.002	0.998	0.000
D56.3 Thalassaemia trait	0.002	0.998	0.000
D56.2 Delta-beta thalassaemia	0.002	0.998	0.000
D56.1 Beta thalassaemia	0.002	0.998	0.000
D56.0 Alpha thalassaemia	0.002	0.998	0.000
D57.8 Other sickle-cell disorders	0.002	0.998	0.000
D57.3 Sickle-cell trait	0.002	0.998	0.000
D57.2 Double heterozygous sickling disorders	0.002	0.998	0.000
D57.1 Sickle-cell anaemia without crisis	0.002	0.998	0.000
D57.0 Sickle-cell anaemia with crisis	0.002	0.998	0.000
T39.4 Antirheumatics, not elsewhere classified	0.002	0.998	0.000
T39.2 Pyrazolone derivatives	0.002	0.998	0.000
Y52 Agents primarily affecting the cardiovascular system	0.002	0.998	0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.000	0.998	0.002
D58.9 Hereditary haemolytic anaemia, unspecified	0.001	0.998	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.001	0.998	0.000
D58.2 Other haemoglobinopathies	0.001	0.998	0.000
D58.1 Hereditary elliptocytosis	0.001	0.998	0.000
N89.6 Tight hymenal ring	0.002	0.998	0.000
R94.5 Abnormal results of liver function studies	0.002	0.998	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.002	0.998	0.000
T85.2 Mechanical complication of intraocular lens	0.000	0.998	0.002
Y40.0 Penicillins	0.002	0.998	0.000
Y40 Systemic antibiotics	0.002	0.998	0.000
G40.8 Other epilepsy	0.000	0.998	0.002
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.002	0.998	0.000
T45.5 Anticoagulants	0.002	0.998	0.000
Y45.2 Propionic acid derivatives	0.002	0.998	0.000
S52.61 Fracture of lower end of both ulna and radius (open)	0.002	0.998	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.002	0.998	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.002	0.998	0.000
Y44 Agents primarily affecting blood constituents	0.002	0.998	0.000
G40.7 Petit mal, unspecified, without grand mal seizures	0.000	0.998	0.002
G40.5 Special epileptic syndromes	0.000	0.998	0.002
G40.4 Other generalised epilepsy and epileptic syndromes	0.000	0.998	0.002
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.000	0.998	0.002
T38.9 Other and unspecified hormone antagonists	0.002	0.998	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.002	0.998	0.000
T38.7 Androgens and anabolic congeners	0.002	0.998	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.002	0.998	0.000
T38.5 Other oestrogens and progestogens	0.002	0.998	0.000
T38.4 Oral contraceptives	0.002	0.998	0.000
T38.2 Antithyroid drugs	0.002	0.998	0.000
T38.1 Thyroid hormones and substitutes	0.002	0.998	0.000
T38.0 Glucocorticoids and synthetic analogues	0.002	0.998	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.002	0.998	0.000
T50.8 Diagnostic agents	0.002	0.998	0.000
T50.7 Analeptics and opioid receptor antagonists	0.002	0.998	0.000
T50.5 Appetite depressants	0.002	0.998	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.002	0.998	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.002	0.998	0.000
T50.1 Loop [high-ceiling] diuretics	0.002	0.998	0.000
T50.0 Mineralocorticoids and their antagonists	0.002	0.998	0.000
Y43.4 Immunosuppressive agents	0.002	0.998	0.000
D58.0 Hereditary spherocytosis	0.001	0.998	0.000
D64.8 Other specified anaemias	0.002	0.998	0.000
H33.5 Other retinal detachments	0.002	0.998	0.000
N89.7 Haematocolpos	0.002	0.998	0.000
N89.4 Leukoplakia of vagina	0.002	0.998	0.000
N89.3 Dysplasia of vagina, unspecified	0.002	0.998	0.000
N89.2 Severe vaginal dysplasia, not elsewhere classified	0.002	0.998	0.000
N89.1 Moderate vaginal dysplasia	0.002	0.998	0.000
N89.0 Mild vaginal dysplasia	0.002	0.998	0.000
T36.9 Systemic antibiotic, unspecified	0.002	0.998	0.000
T36.8 Other systemic antibiotics	0.002	0.998	0.000
T36.7 Antifungal antibiotics, systemically used	0.002	0.998	0.000
T36.6 Rifamycins	0.002	0.998	0.000
T36.5 Aminoglycosides	0.002	0.998	0.000
T36.4 Tetracyclines	0.002	0.998	0.000
T36.3 Macrolides	0.002	0.998	0.000
T36.2 Chloramphenicol group	0.002	0.998	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.002	0.998	0.000
T36.0 Penicillins	0.002	0.998	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.002	0.998	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.002	0.998	0.000
T37.5 Antiviral drugs	0.002	0.998	0.000
T37.4 Anthelminthics	0.002	0.998	0.000
T37.3 Other antiprotozoal drugs	0.002	0.998	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.002	0.998	0.000
T37.1 Antimycobacterial drugs	0.002	0.998	0.000
T37.0 Sulphonamides	0.002	0.998	0.000
T41.5 Therapeutic gases	0.002	0.998	0.000
T41.4 Anaesthetic, unspecified	0.002	0.998	0.000
T41.3 Local anaesthetics	0.002	0.998	0.000
T41.2 Other and unspecified general anaesthetics	0.002	0.998	0.000
T41.1 Intravenous anaesthetics	0.002	0.998	0.000
T41.0 Inhaled anaesthetics	0.002	0.998	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.002	0.998	0.000
T45.8 Other primarily systemic and haematological agents	0.002	0.998	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.000
T45.6 Fibrinolysis-affecting drugs	0.002	0.998	0.000
T45.4 Iron and its compounds	0.002	0.998	0.000
T45.3 Enzymes, not elsewhere classified	0.002	0.998	0.000
T45.2 Vitamins, not elsewhere classified	0.002	0.998	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.002	0.998	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.002	0.998	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.002	0.998	0.000
T48.5 Anti-common-cold drugs	0.002	0.998	0.000
T48.4 Expectorants	0.002	0.998	0.000
T48.3 Antitussives	0.002	0.998	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.002	0.998	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.002	0.998	0.000
T48.0 Oxytocic drugs	0.002	0.998	0.000
T49.9 Topical agent, unspecified	0.002	0.998	0.000
T49.8 Other topical agents	0.002	0.998	0.000
T49.7 Dental drugs, topically applied	0.002	0.998	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.002	0.998	0.000
T49.5 Ophthalmological drugs and preparations	0.002	0.998	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.002	0.998	0.000
T49.3 Emollients, demulcents and protectants	0.002	0.998	0.000
T49.2 Local astringents and local detergents	0.002	0.998	0.000
T49.1 Antipruritics	0.002	0.998	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.998	0.000
T50.4 Drugs affecting uric acid metabolism	0.002	0.998	0.000
Y45.5 4-Aminophenol derivatives	0.002	0.998	0.000
Y45.1 Salicylates	0.002	0.998	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
M13.99 Arthritis, unspecified (Site unspecified)	0.002	0.998	0.000
H33.4 Traction detachment of retina	0.002	0.998	0.000
N50.8 Other specified disorders of male genital organs	0.002	0.998	0.000
Y45.0 Opioids and related analgesics	0.002	0.998	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.000	0.998	0.002
Y51 Drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
D64.4 Congenital dyserythropoietic anaemia	0.002	0.998	0.000
D64.3 Other sideroblastic anaemias	0.002	0.998	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.002	0.998	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.002	0.998	0.000
D64.0 Hereditary sideroblastic anaemia	0.002	0.998	0.000
T45.0 Antiallergic and antiemetic drugs	0.001	0.998	0.000
D53.9 Nutritional anaemia, unspecified	0.001	0.998	0.000
D53.8 Other specified nutritional anaemias	0.001	0.998	0.000
D53.2 Scorbutic anaemia	0.001	0.998	0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.001	0.998	0.000
D53.0 Protein deficiency anaemia	0.001	0.998	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.001	0.998	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.001	0.998	0.000
T47.7 Emetics	0.001	0.998	0.000
T47.6 Antidiarrhoeal drugs	0.001	0.998	0.000
T47.5 Digestants	0.001	0.998	0.000
T47.4 Other laxatives	0.001	0.998	0.000
T47.3 Saline and osmotic laxatives	0.001	0.998	0.000
T47.2 Stimulant laxatives	0.001	0.998	0.000
T47.0 Histamine H(2)-receptor antagonists	0.001	0.998	0.000
Z96.6 Presence of orthopaedic joint implants	0.002	0.998	0.000
Y57 Other and unspecified drugs and medicaments	0.002	0.998	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.002	0.998	0.000
Y45.8 Other analgesics and antipyretics	0.002	0.998	0.000
Y45.4 Antirheumatics	0.002	0.998	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.002	0.998	0.000
H30 Chorioretinal inflammation	0.002	0.998	0.000
N89.5 Stricture and atresia of vagina	0.002	0.998	0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.000	0.998	0.002
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.000	0.998	0.002
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.000	0.998	0.002
R33 Retention of urine	0.002	0.998	0.000
T81 Complications of procedures, not elsewhere classified	0.000	0.998	0.002
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.002	0.998	0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.000	0.998	0.001
T39.0 Salicylates	0.001	0.998	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.001	0.998	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.001	0.998	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.001	0.998	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.001	0.998	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.001	0.998	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.001	0.998	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.001	0.998	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.001	0.998	0.000
T44.0 Anticholinesterase agents	0.001	0.998	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.001	0.998	0.000
Y59 Other and unspecified vaccines and biological substances	0.002	0.998	0.000
Y58 Bacterial vaccines	0.002	0.998	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.002	0.998	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.002	0.998	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.001	0.998	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.001	0.998	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.001	0.998	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.001	0.998	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.001	0.998	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.001	0.998	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.001	0.998	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.001	0.998	0.000
H33.0 Retinal detachment with retinal break	0.002	0.998	0.000
M07.6 Other enteropathic arthropathies	0.001	0.998	0.000
M07.5 Arthropathy in ulcerative colitis	0.001	0.998	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.001	0.998	0.000
M07.2 Psoriatic spondylitis	0.001	0.998	0.000
M07.1 Arthritis mutilans	0.001	0.998	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.001	0.998	0.000
M10.9 Gout, unspecified	0.002	0.998	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.001	0.998	0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.000	0.998	0.001
Y43.0 Antiallergic and antiemetic drugs	0.001	0.998	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.001	0.998	0.000
Y48 Anaesthetics and therapeutic gases	0.001	0.998	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.000	0.998	0.002
D52.8 Other folate deficiency anaemias	0.001	0.998	0.000
D52.1 Drug-induced folate deficiency anaemia	0.001	0.998	0.000
D52.0 Dietary folate deficiency anaemia	0.001	0.998	0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.000	0.998	0.001
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.000	0.998	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations