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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75807633
log Bayes Factor = 18.3777
Chromosome 6   position 135,495,020  (GRCh37) Explore rs75807633 on Ensembl!
Variant rs75807633 is part of Cluster X0253

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
I30-I52 Other forms of heart disease
0.997 0.003 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.996 0.004 0.000
Chapter XXI Factors influencing health status and contact with health services
0.994 0.006 0.000
J40-J47 Chronic lower respiratory diseases
0.992 0.008 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.991 0.009 0.000
Chapter II Neoplasms
0.986 0.014 0.000
I50 Heart failure
0.984 0.016 0.000
O60-O75 Complications of labour and delivery
0.984 0.016 0.000
C15-C26 Malignant neoplasms of digestive organs
0.981 0.019 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.978 0.022 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.975 0.025 0.000
J09-J18 Influenza and pneumonia
0.973 0.027 0.000
Chapter XX External causes of morbidity and mortality
0.969 0.031 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.965 0.035 0.000
C20 Malignant neoplasm of rectum
0.964 0.036 0.000
E00-E07 Disorders of thyroid gland
0.963 0.037 0.000
E03 Other hypothyroidism
0.960 0.040 0.000
I51 Complications and ill-defined descriptions of heart disease
0.960 0.040 0.000
E03.9 Hypothyroidism, unspecified
0.959 0.041 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.956 0.044 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.956 0.044 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.955 0.045 0.000
G90-G99 Other disorders of the nervous system
0.954 0.046 0.000
J30-J39 Other diseases of upper respiratory tract
0.949 0.051 0.000
M50-M54 Other dorsopathies
0.948 0.052 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.948 0.052 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.944 0.056 0.000
I50.0 Congestive heart failure
0.939 0.061 0.000
O70 Perineal laceration during delivery
0.935 0.065 0.000
G50 Disorders of trigeminal nerve
0.935 0.065 0.000
J18 Pneumonia, organism unspecified
0.934 0.066 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.928 0.072 0.000
D00-D09 In situ neoplasms
0.926 0.074 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.925 0.075 0.000
R30-R39 Symptoms and signs involving the urinary system
0.916 0.084 0.000
I51.8 Other ill-defined heart diseases
0.911 0.089 0.000
J43 Emphysema
0.911 0.089 0.000
G93 Other disorders of brain
0.909 0.091 0.000
M40-M43 Deforming dorsopathies
0.908 0.092 0.000
O70.0 First degree perineal laceration during delivery
0.908 0.092 0.000
Z43 Attention to artificial openings
0.906 0.094 0.000
J18.9 Pneumonia, unspecified
0.906 0.094 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.906 0.094 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.905 0.095 0.000
M20-M25 Other joint disorders
0.901 0.099 0.000
I50.9 Heart failure, unspecified
0.900 0.100 0.000
Z12 Special screening examination for neoplasms
0.898 0.102 0.000
M54 Dorsalgia
0.896 0.104 0.000
G50.0 Trigeminal neuralgia
0.895 0.105 0.000
R26 Abnormalities of gait and mobility
0.894 0.106 0.000
Y95 Nosocomial condition
0.893 0.107 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.891 0.109 0.000
J35 Chronic diseases of tonsils and adenoids
0.891 0.109 0.000
J47 Bronchiectasis
0.889 0.111 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.884 0.116 0.000
J44 Other chronic obstructive pulmonary disease
0.884 0.116 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.883 0.117 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.880 0.120 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.879 0.121 0.000
J45 Asthma
0.879 0.121 0.000
M45-M49 Spondylopathies
0.878 0.122 0.000
O48 Prolonged pregnancy
0.874 0.126 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.874 0.126 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.872 0.128 0.000
J33 Nasal polyp
0.870 0.130 0.000
G40-G47 Episodic and paroxysmal disorders
0.868 0.132 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.867 0.133 0.000
R39 Other symptoms and signs involving the urinary system
0.865 0.135 0.000
I80 Phlebitis and thrombophlebitis
0.864 0.136 0.000
Chapter I Certain infectious and parasitic diseases
0.864 0.136 0.000
R47-R49 Symptoms and signs involving speech and voice
0.860 0.140 0.000
I35 Nonrheumatic aortic valve disorders
0.854 0.146 0.000
J43.9 Emphysema, unspecified
0.852 0.148 0.000
Z45 Adjustment and management of implanted device
0.850 0.150 0.000
I51.7 Cardiomegaly
0.850 0.150 0.000
Z12.1 Special screening examination for neoplasm of intestinal tract
0.850 0.150 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.849 0.151 0.000
C60-C63 Malignant neoplasms of male genital organs
0.849 0.151 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.847 0.153 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.843 0.157 0.000
R50-R69 General symptoms and signs
0.843 0.157 0.000
M70-M79 Other soft tissue disorders
0.842 0.158 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.842 0.158 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.842 0.158 0.000
J00-J06 Acute upper respiratory infections
0.838 0.162 0.000
O30 Multiple gestation
0.836 0.164 0.000
J35.0 Chronic tonsillitis
0.834 0.166 0.000
I44 Atrioventricular and left bundle-branch block
0.832 0.168 0.000
M43 Other deforming dorsopathies
0.831 0.169 0.000
M65-M68 Disorders of synovium and tendon
0.827 0.172 0.000
D05 Carcinoma in situ of breast
0.827 0.173 0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.826 0.174 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.826 0.174 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.824 0.176 0.000
G93.3 Postviral fatigue syndrome
0.823 0.177 0.000
R30 Pain associated with micturition
0.818 0.182 0.000
O36 Maternal care for other known or suspected foetal problems
0.818 0.182 0.000
J60-J70 Lung diseases due to external agents
0.818 0.182 0.000
M54.5 Low back pain
0.814 0.186 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.813 0.187 0.000
G58 Other mononeuropathies
0.811 0.189 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.810 0.190 0.000
E70-E90 Metabolic disorders
0.810 0.190 0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons
0.809 0.191 0.000
I49 Other cardiac arrhythmias
0.809 0.191 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.807 0.193 0.000
M05-M14 Inflammatory polyarthropathies
0.807 0.193 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.807 0.193 0.000
J33.8 Other polyp of sinus
0.806 0.194 0.000
C18 Malignant neoplasm of colon
0.806 0.194 0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm
0.804 0.196 0.000
J45.0 Predominantly allergic asthma
0.803 0.197 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.803 0.197 0.000
I95 Hypotension
0.803 0.197 0.000
G40 Epilepsy
0.802 0.198 0.000
M47 Spondylosis
0.802 0.198 0.000
O47 False labour
0.802 0.198 0.000
I50.1 Left ventricular failure
0.801 0.199 0.000
R22.9 Localised swelling, mass and lump, unspecified
0.799 0.201 0.000
M80-M85 Disorders of bone density and structure
0.799 0.201 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.798 0.202 0.000
B95-B98 Bacterial, viral and other infectious agents
0.797 0.203 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.795 0.205 0.000
J95-J99 Other diseases of the respiratory system
0.795 0.205 0.000
G20-G26 Extrapyramidal and movement disorders
0.794 0.206 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.794 0.206 0.000
R22.3 Localised swelling, mass and lump, upper limb
0.793 0.207 0.000
S00-S09 Injuries to the head
0.792 0.208 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.792 0.208 0.000
I35.0 Aortic (valve) stenosis
0.790 0.210 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.789 0.211 0.000
R23 Other skin changes
0.789 0.211 0.000
R26.0 Ataxic gait
0.789 0.211 0.000
G56 Mononeuropathies of upper limb
0.787 0.213 0.000
E20-E35 Disorders of other endocrine glands
0.785 0.215 0.000
Chapter VII Diseases of the eye and adnexa
0.785 0.215 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.784 0.216 0.000
Z46 Fitting and adjustment of other devices
0.784 0.216 0.000
M35 Other systemic involvement of connective tissue
0.783 0.217 0.000
Z50 Care involving use of rehabilitation procedures
0.782 0.218 0.000
Z43.4 Attention to other artificial openings of digestive tract
0.779 0.221 0.000
J36 Peritonsillar abscess
0.778 0.222 0.000
M86-M90 Other osteopathies
0.778 0.222 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.778 0.222 0.000
G93.9 Disorder of brain, unspecified
0.777 0.223 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.776 0.224 0.000
M43.1 Spondylolisthesis
0.776 0.224 0.000
G54 Nerve root and plexus disorders
0.774 0.226 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.774 0.226 0.000
Z92 Personal history of medical treatment
0.773 0.227 0.000
M31 Other necrotising vasculopathies
0.772 0.228 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.772 0.228 0.000
Z93 Artificial opening status
0.772 0.228 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.771 0.229 0.000
M91-M94 Chondropathies
0.771 0.229 0.000
M54.4 Lumbago with sciatica
0.771 0.229 0.000
O80-O84 Delivery
0.770 0.230 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.770 0.230 0.000
I95.9 Hypotension, unspecified
0.768 0.232 0.000
Z43.3 Attention to colostomy
0.767 0.233 0.000
R22.4 Localised swelling, mass and lump, lower limb
0.767 0.233 0.000
G70-G73 Diseases of myoneural junction and muscle
0.767 0.233 0.000
M51 Other intervertebral disk disorders
0.766 0.234 0.000
Chapter XXII Codes for special purposes
0.766 0.234 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.766 0.234 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.765 0.235 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.761 0.239 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.760 0.240 0.000
R22.0 Localised swelling, mass and lump, head
0.759 0.240 0.000
V80-V89 Other land transport accidents
0.759 0.241 0.000
I26 Pulmonary embolism
0.757 0.243 0.000
C15 Malignant neoplasm of oesophagus
0.756 0.243 0.000
W20-W49 Exposure to inanimate mechanical forces
0.755 0.245 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.755 0.245 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.755 0.245 0.000
G40.9 Epilepsy, unspecified
0.754 0.246 0.000
O62 Abnormalities of forces of labour
0.754 0.246 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.754 0.246 0.000
C61 Malignant neoplasm of prostate
0.750 0.250 0.000
R59 Enlarged lymph nodes
0.750 0.250 0.000
M47.9 Spondylosis, unspecified
0.750 0.250 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.749 0.251 0.000
X60-X84 Intentional self-harm
0.749 0.251 0.000
R30.0 Dysuria
0.748 0.252 0.000
Z13 Special screening examination for other diseases and disorders
0.748 0.252 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.747 0.253 0.000
I83 Varicose veins of lower extremities
0.747 0.253 0.000
J42 Unspecified chronic bronchitis
0.746 0.254 0.000
M24 Other specific joint derangements
0.745 0.255 0.000
Z45.1 Adjustment and management of infusion pump
0.744 0.256 0.000
D06 Carcinoma in situ of cervix uteri
0.743 0.257 0.000
M54.56 Low back pain (Lumbar region)
0.742 0.258 0.000
O69.1 Labour and delivery complicated by cord around neck, with compression
0.742 0.258 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.741 0.259 0.000
O66 Other obstructed labour
0.741 0.259 0.000
Z97 Presence of other devices
0.740 0.260 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.739 0.261 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.738 0.261 0.000
I05-I09 Chronic rheumatic heart diseases
0.738 0.262 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.738 0.262 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.737 0.263 0.000
R47 Speech disturbances, not elsewhere classified
0.737 0.263 0.000
O30.0 Twin pregnancy
0.736 0.264 0.000
Z43.2 Attention to ileostomy
0.735 0.265 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.735 0.265 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.735 0.265 0.000
G57 Mononeuropathies of lower limb
0.734 0.266 0.000
S70-S79 Injuries to the hip and thigh
0.734 0.266 0.000
T66-T78 Other and unspecified effects of external causes
0.733 0.267 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.732 0.268 0.000
O63 Long labour
0.731 0.269 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.730 0.269 0.000
S80-S89 Injuries to the knee and lower leg
0.730 0.270 0.000
Chapter XI Diseases of the digestive system
0.730 0.270 0.000
E40-E46 Malnutrition
0.728 0.272 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.728 0.272 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.727 0.273 0.000
C50-C50 Malignant neoplasm of breast
0.725 0.275 0.000
Z53.8 Procedure not carried out for other reasons
0.724 0.276 0.000
Z41 Procedures for purposes other than remedying health state
0.724 0.276 0.000
Z45.2 Adjustment and management of vascular access device
0.724 0.276 0.000
J33.9 Nasal polyp, unspecified
0.723 0.277 0.000
R22.1 Localised swelling, mass and lump, neck
0.722 0.278 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.722 0.278 0.000
G93.0 Cerebral cysts
0.722 0.278 0.000
R50 Fever of unknown origin
0.722 0.278 0.000
S60-S69 Injuries to the wrist and hand
0.722 0.278 0.000
M25 Other joint disorders, not elsewhere classified
0.721 0.279 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.721 0.279 0.000
D03 Melanoma in situ
0.719 0.281 0.000
R55 Syncope and collapse
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.717 0.283 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
M54.1 Radiculopathy
0.716 0.283 0.000
O85-O92 Complications predominantly related to the puerperium
0.716 0.284 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
C18.9 Colon, unspecified
0.716 0.284 0.000
G35 Multiple sclerosis
0.716 0.284 0.000
I52 Other heart disorders in diseases classified elsewhere
0.715 0.285 0.000
I48 Atrial fibrillation and flutter
0.715 0.285 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.715 0.285 0.000
I41 Myocarditis in diseases classified elsewhere
0.715 0.285 0.000
I40 Acute myocarditis
0.715 0.285 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.715 0.285 0.000
I37 Pulmonary valve disorders
0.715 0.285 0.000
I36 Nonrheumatic tricuspid valve disorders
0.715 0.285 0.000
I32 Pericarditis in diseases classified elsewhere
0.715 0.285 0.000
I30 Acute pericarditis
0.715 0.285 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.714 0.286 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.713 0.287 0.000
G37 Other demyelinating diseases of central nervous system
0.712 0.288 0.000
J41 Simple and mucopurulent chronic bronchitis
0.711 0.289 0.000
G41 Status epilepticus
0.711 0.289 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.710 0.289 0.000
G52 Disorders of other cranial nerves
0.710 0.289 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.710 0.290 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.709 0.291 0.000
Z43.6 Attention to other artificial openings of urinary tract
0.708 0.292 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.707 0.293 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.707 0.293 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.707 0.293 0.000
I42 Cardiomyopathy
0.707 0.293 0.000
D04 Carcinoma in situ of skin
0.707 0.293 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.706 0.294 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.706 0.294 0.000
O74 Complications of anaesthesia during labour and delivery
0.705 0.295 0.000
O73 Retained placenta and membranes, without haemorrhage
0.705 0.295 0.000
O71 Other obstetric trauma
0.705 0.295 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.705 0.295 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.705 0.295 0.000
O61 Failed induction of labour
0.705 0.295 0.000
O60 Preterm delivery
0.705 0.295 0.000
I33 Acute and subacute endocarditis
0.705 0.295 0.000
E07 Other disorders of thyroid
0.705 0.295 0.000
I74 Arterial embolism and thrombosis
0.705 0.295 0.000
I82 Other venous embolism and thrombosis
0.704 0.296 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.704 0.296 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.704 0.296 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.704 0.296 0.000
C21 Malignant neoplasm of anus and anal canal
0.704 0.296 0.000
C17 Malignant neoplasm of small intestine
0.704 0.296 0.000
C16 Malignant neoplasm of stomach
0.704 0.296 0.000
C23 Malignant neoplasm of gallbladder
0.704 0.296 0.000
J39 Other diseases of upper respiratory tract
0.703 0.297 0.000
J35.1 Hypertrophy of tonsils
0.702 0.298 0.000
O45 Premature separation of placenta [abruptio placentae]
0.699 0.301 0.000
O44 Placenta praevia
0.699 0.301 0.000
O43 Placental disorders
0.699 0.301 0.000
O41 Other disorders of amniotic fluid and membranes
0.699 0.301 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.699 0.301 0.000
O33 Maternal care for known or suspected disproportion
0.699 0.301 0.000
O31 Complications specific to multiple gestation
0.699 0.301 0.000
O40 Polyhydramnios
0.699 0.301 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.698 0.302 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.698 0.302 0.000
J17 Pneumonia in diseases classified elsewhere
0.698 0.302 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.698 0.302 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.698 0.302 0.000
J12 Viral pneumonia, not elsewhere classified
0.698 0.302 0.000
J11 Influenza, virus not identified
0.698 0.302 0.000
J10 Influenza due to identified influenza virus
0.698 0.302 0.000
J14 Pneumonia due to Haemophilus influenzae
0.698 0.302 0.000
J09 Influenza due to certain identified influenza virus
0.698 0.302 0.000
Z04 Examination and observation for other reasons
0.697 0.303 0.000
M21 Other acquired deformities of limbs
0.696 0.303 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.696 0.304 0.000
S90-S99 Injuries to the ankle and foot
0.696 0.304 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.695 0.305 0.000
Y35-Y36 Legal intervention and operations of war
0.695 0.305 0.000
Y10-Y34 Event of undetermined intent
0.695 0.305 0.000
Y00-Y09 Assault
0.695 0.305 0.000
X85-X99 Assault
0.695 0.305 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.695 0.305 0.000
X50-X57 Overexertion, travel and privation
0.695 0.305 0.000
X30-X39 Exposure to forces of nature
0.695 0.305 0.000
X20-X29 Contact with venomous animals and plants
0.695 0.305 0.000
X10-X19 Contact with heat and hot substances
0.695 0.305 0.000
X00-X09 Exposure to smoke, fire and flames
0.695 0.305 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.695 0.305 0.000
W75-W84 Other accidental threats to breathing
0.695 0.305 0.000
W65-W74 Accidental drowning and submersion
0.695 0.305 0.000
W50-W64 Exposure to animate mechanical forces
0.695 0.305 0.000
V98-V99 Other and unspecified transport accidents
0.695 0.305 0.000
V95-V97 Air and space transport accidents
0.695 0.305 0.000
V90-V94 Water transport accidents
0.695 0.305 0.000
V70-V79 Bus occupant injured in transport accident
0.695 0.305 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.695 0.305 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.695 0.305 0.000
V40-V49 Car occupant injured in transport accident
0.695 0.305 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.695 0.305 0.000
V20-V29 Motorcycle rider injured in transport accident
0.695 0.305 0.000
V01-V09 Pedestrian injured in transport accident
0.695 0.305 0.000
R51 Headache
0.694 0.306 0.000
Y40 Systemic antibiotics
0.692 0.307 0.000
B25-B34 Other viral diseases
0.692 0.308 0.000
Z10 Routine general health check-up of defined subpopulation
0.692 0.308 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.692 0.308 0.000
O42 Premature rupture of membranes
0.691 0.309 0.000
T86 Failure and rejection of transplanted organs and tissues
0.691 0.309 0.000
E06 Thyroiditis
0.690 0.310 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.690 0.310 0.000
E00 Congenital iodine-deficiency syndrome
0.690 0.310 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.690 0.310 0.000
S01 Open wound of head
0.690 0.310 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.690 0.310 0.000
E03.8 Other specified hypothyroidism
0.689 0.311 0.000
E03.5 Myxoedema coma
0.689 0.311 0.000
E03.4 Atrophy of thyroid (acquired)
0.689 0.311 0.000
E03.3 Postinfectious hypothyroidism
0.689 0.311 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.689 0.311 0.000
E03.1 Congenital hypothyroidism without goitre
0.689 0.311 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.689 0.311 0.000
I51.6 Cardiovascular disease, unspecified
0.688 0.312 0.000
I51.5 Myocardial degeneration
0.688 0.312 0.000
I51.4 Myocarditis, unspecified
0.688 0.312 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.688 0.312 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.688 0.312 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.688 0.312 0.000
I51.0 Cardiac septal defect, acquired
0.688 0.312 0.000
Y43 Primarily systemic agents
0.688 0.312 0.000
R25 Abnormal involuntary movements
0.687 0.313 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.687 0.313 0.000
M41 Scoliosis
0.687 0.313 0.000
L40-L45 Papulosquamous disorders
0.687 0.313 0.000
H53-H54 Visual disturbances and blindness
0.687 0.313 0.000
R26.3 Immobility
0.687 0.313 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.686 0.313 0.000
G51 Facial nerve disorders
0.686 0.313 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.686 0.314 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.686 0.314 0.000
R35 Polyuria
0.686 0.314 0.000
R27 Other lack of coordination
0.685 0.314 0.000
Z54 Convalescence
0.685 0.314 0.000
Z52 Donors of organs and tissues
0.685 0.314 0.000
Z49 Care involving dialysis
0.685 0.314 0.000
Z44 Fitting and adjustment of external prosthetic device
0.685 0.314 0.000
Z96 Presence of other functional implants
0.685 0.315 0.000
S50-S59 Injuries to the elbow and forearm
0.685 0.315 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.685 0.315 0.000
I44.1 Atrioventricular block, second degree
0.685 0.315 0.000
Q60-Q64 Congenital malformations of the urinary system
0.684 0.315 0.000
T33-T35 Frostbite
0.684 0.315 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.684 0.315 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.684 0.315 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.684 0.315 0.000
T00-T07 Injuries involving multiple body regions
0.684 0.315 0.000
S10-S19 Injuries to the neck
0.684 0.315 0.000
O36.6 Maternal care for excessive foetal growth
0.684 0.316 0.000
J69 Pneumonitis due to solids and liquids
0.684 0.316 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.684 0.316 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.684 0.316 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.684 0.316 0.000
G96 Other disorders of central nervous system
0.684 0.316 0.000
G95 Other diseases of spinal cord
0.684 0.316 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.684 0.316 0.000
G90 Disorders of autonomic nervous system
0.684 0.316 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.684 0.316 0.000
G92 Toxic encephalopathy
0.684 0.316 0.000
G58.8 Other specified mononeuropathies
0.682 0.317 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.682 0.318 0.000
I38 Endocarditis, valve unspecified
0.682 0.318 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.682 0.318 0.000
L50-L54 Urticaria and erythema
0.681 0.319 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.681 0.319 0.000
O36.9 Maternal care for foetal problem, unspecified
0.681 0.319 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.680 0.319 0.000
J37 Chronic laryngitis and laryngotracheitis
0.680 0.320 0.000
M31.6 Other giant cell arteritis
0.680 0.320 0.000
M53 Other dorsopathies, not elsewhere classified
0.679 0.320 0.000
R22.2 Localised swelling, mass and lump, trunk
0.679 0.321 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.679 0.321 0.000
I27 Other pulmonary heart diseases
0.679 0.321 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.679 0.321 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.677 0.322 0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm
0.677 0.323 0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm
0.677 0.323 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.677 0.323 0.000
S40-S49 Injuries to the shoulder and upper arm
0.677 0.323 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.676 0.324 0.000
T79-T79 Certain early complications of trauma
0.676 0.324 0.000
C92 Myeloid leukaemia
0.674 0.326 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.674 0.326 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.672 0.328 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.671 0.329 0.000
O70.9 Perineal laceration during delivery, unspecified
0.671 0.329 0.000
O70.3 Fourth degree perineal laceration during delivery
0.671 0.329 0.000
J40 Bronchitis, not specified as acute or chronic
0.670 0.329 0.000
G50.9 Disorder of trigeminal nerve, unspecified
0.670 0.330 0.000
G50.8 Other disorders of trigeminal nerve
0.670 0.330 0.000
G50.1 Atypical facial pain
0.670 0.330 0.000
R49 Voice disturbances
0.670 0.330 0.000
C25 Malignant neoplasm of pancreas
0.669 0.330 0.000
R23.3 Spontaneous ecchymoses
0.669 0.331 0.000
J18.8 Other pneumonia, organism unspecified
0.669 0.331 0.000
J18.2 Hypostatic pneumonia, unspecified
0.669 0.331 0.000
J18.0 Bronchopneumonia, unspecified
0.669 0.331 0.000
I49.8 Other specified cardiac arrhythmias
0.669 0.331 0.000
J30 Vasomotor and allergic rhinitis
0.669 0.331 0.000
M65 Synovitis and tenosynovitis
0.669 0.331 0.000
B15-B19 Viral hepatitis
0.668 0.332 0.000
G30-G32 Other degenerative diseases of the nervous system
0.668 0.332 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.668 0.332 0.000
M54.3 Sciatica
0.668 0.332 0.000
Z93.2 Ileostomy status
0.667 0.333 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.666 0.334 0.000
R22.7 Localised swelling, mass and lump, multiple sites
0.666 0.334 0.000
O70.2 Third degree perineal laceration during delivery
0.666 0.334 0.000
M50 Cervical disk disorders
0.665 0.335 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.664 0.335 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.664 0.336 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.664 0.336 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.664 0.336 0.000
Z89 Acquired absence of limb
0.663 0.337 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.663 0.337 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.663 0.337 0.000
Y98 Lifestyle-related condition
0.663 0.337 0.000
Y97 Environmental-pollution-related condition
0.663 0.337 0.000
Y96 Work-related condition
0.663 0.337 0.000
J18.1 Lobar pneumonia, unspecified
0.663 0.337 0.000
R63 Symptoms and signs concerning food and fluid intake
0.662 0.338 0.000
D09 Carcinoma in situ of other and unspecified sites
0.660 0.339 0.000
Z46.6 Fitting and adjustment of urinary device
0.660 0.339 0.000
Z40 Prophylactic surgery
0.660 0.340 0.000
M35.3 Polymyalgia rheumatica
0.660 0.340 0.000
J46 Status asthmaticus
0.658 0.342 0.000
R36 Urethral discharge
0.657 0.343 0.000
R34 Anuria and oliguria
0.657 0.343 0.000
C97 Malignant neoplasms of independent (primary) multiple sites
0.656 0.344 0.000
I47 Paroxysmal tachycardia
0.656 0.344 0.000
C81 Hodgkin's disease
0.656 0.344 0.000
O72 Postpartum haemorrhage
0.656 0.344 0.000
Z92.3 Personal history of irradiation
0.656 0.344 0.000
R59.1 Generalised enlarged lymph nodes
0.656 0.344 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.656 0.344 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.655 0.344 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.653 0.347 0.000
R50.8 Other specified fever
0.653 0.347 0.000
C85.1 B-cell lymphoma, unspecified
0.653 0.347 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.653 0.347 0.000
J43.8 Other emphysema
0.653 0.347 0.000
J43.2 Centrilobular emphysema
0.653 0.347 0.000
J43.1 Panlobular emphysema
0.653 0.347 0.000
J43.0 MacLeod's syndrome
0.653 0.347 0.000
O36.5 Maternal care for poor foetal growth
0.652 0.348 0.000
G93.8 Other specified disorders of brain
0.652 0.348 0.000
G93.7 Reye's syndrome
0.652 0.348 0.000
G93.6 Cerebral oedema
0.652 0.348 0.000
G93.5 Compression of brain
0.652 0.348 0.000
G93.4 Encephalopathy, unspecified
0.652 0.348 0.000
G93.2 Benign intracranial hypertension
0.652 0.348 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.652 0.348 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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