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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75876943
log Bayes Factor = 15.0045
Chromosome 12   position 86,555,845  (GRCh37) Explore rs75876943 on Ensembl!
Variant rs75876943 is part of Cluster X0042

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Z51 Other medical care
1.000 0.000 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
1.000 0.000 0.000
Z51.1 Chemotherapy session for neoplasm
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
Chapter VI Diseases of the nervous system
0.999 0.001 0.000
Chapter XXI Factors influencing health status and contact with health services
0.997 0.003 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.995 0.005 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.993 0.007 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.992 0.008 0.000
Chapter IX Diseases of the circulatory system
0.988 0.012 0.000
M05-M14 Inflammatory polyarthropathies
0.984 0.016 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.979 0.021 0.000
M50-M54 Other dorsopathies
0.974 0.026 0.000
C15-C26 Malignant neoplasms of digestive organs
0.970 0.030 0.000
Z45 Adjustment and management of implanted device
0.970 0.030 0.000
Chapter XI Diseases of the digestive system
0.969 0.031 0.000
C79 Secondary malignant neoplasm of other sites
0.969 0.031 0.000
K55-K64 Other diseases of intestines
0.968 0.032 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.966 0.034 0.000
M45-M49 Spondylopathies
0.961 0.039 0.000
K63 Other diseases of intestine
0.960 0.040 0.000
Chapter VIII Diseases of the ear and mastoid process
0.960 0.040 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.959 0.041 0.000
Z51.5 Palliative care
0.958 0.042 0.000
Z45.2 Adjustment and management of vascular access device
0.956 0.044 0.000
M06 Other rheumatoid arthritis
0.956 0.044 0.000
K63.5 Polyp of colon
0.951 0.049 0.000
I60-I69 Cerebrovascular diseases
0.951 0.049 0.000
G51 Facial nerve disorders
0.938 0.062 0.000
Chapter XIV Diseases of the genitourinary system
0.938 0.062 0.000
M54 Dorsalgia
0.935 0.065 0.000
M06.9 Rheumatoid arthritis, unspecified
0.932 0.068 0.000
Z43 Attention to artificial openings
0.932 0.068 0.000
M47 Spondylosis
0.929 0.071 0.000
N20-N23 Urolithiasis
0.924 0.076 0.000
I20-I25 Ischaemic heart diseases
0.923 0.077 0.000
I63 Cerebral infarction
0.920 0.080 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.913 0.087 0.000
Chapter I Certain infectious and parasitic diseases
0.912 0.088 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.911 0.089 0.000
C51-C58 Malignant neoplasms of female genital organs
0.910 0.090 0.000
N20 Calculus of kidney and ureter
0.907 0.093 0.000
N60-N64 Disorders of breast
0.907 0.093 0.000
Chapter X Diseases of the respiratory system
0.905 0.095 0.000
M54.5 Low back pain
0.902 0.098 0.000
C18 Malignant neoplasm of colon
0.902 0.098 0.000
K57 Diverticular disease of intestine
0.901 0.099 0.000
G51.0 Bell's palsy
0.897 0.103 0.000
N20.0 Calculus of kidney
0.897 0.103 0.000
Chapter XX External causes of morbidity and mortality
0.896 0.104 0.000
Z46 Fitting and adjustment of other devices
0.895 0.105 0.000
K50-K52 Noninfective enteritis and colitis
0.894 0.106 0.000
G57 Mononeuropathies of lower limb
0.894 0.106 0.000
N63 Unspecified lump in breast
0.894 0.106 0.000
O48 Prolonged pregnancy
0.889 0.111 0.000
A30-A49 Other bacterial diseases
0.886 0.114 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.885 0.115 0.000
M47.8 Other spondylosis
0.879 0.121 0.000
H90-H95 Other disorders of ear
0.878 0.122 0.000
K51 Ulcerative colitis
0.877 0.123 0.000
Z48 Other surgical follow-up care
0.877 0.123 0.000
O00-O08 Pregnancy with abortive outcome
0.875 0.125 0.000
Chapter VII Diseases of the eye and adnexa
0.874 0.126 0.000
C78.0 Secondary malignant neoplasm of lung
0.872 0.128 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.872 0.128 0.000
I21 Acute myocardial infarction
0.868 0.132 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.862 0.138 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.854 0.146 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.853 0.147 0.000
O36 Maternal care for other known or suspected foetal problems
0.853 0.147 0.000
O60-O75 Complications of labour and delivery
0.849 0.151 0.000
Z51.3 Blood transfusion without reported diagnosis
0.846 0.154 0.000
I05-I09 Chronic rheumatic heart diseases
0.845 0.155 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.843 0.157 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.842 0.158 0.000
K58 Irritable bowel syndrome
0.840 0.160 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.838 0.162 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.835 0.165 0.000
M54.59 Low back pain (Site unspecified)
0.834 0.166 0.000
M51 Other intervertebral disk disorders
0.833 0.167 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.829 0.171 0.000
H30-H36 Disorders of choroid and retina
0.829 0.171 0.000
A41 Other septicaemia
0.828 0.172 0.000
N23 Unspecified renal colic
0.826 0.174 0.000
S00-S09 Injuries to the head
0.824 0.176 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.824 0.176 0.000
G57.6 Lesion of plantar nerve
0.821 0.179 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.820 0.180 0.000
M54.57 Low back pain (Lumbosacral region)
0.820 0.180 0.000
H90 Conductive and sensorineural hearing loss
0.819 0.181 0.000
G90-G99 Other disorders of the nervous system
0.819 0.181 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.818 0.182 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.818 0.182 0.000
K55 Vascular disorders of intestine
0.818 0.182 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.813 0.187 0.000
Z43.3 Attention to colostomy
0.812 0.188 0.000
C79.6 Secondary malignant neoplasm of ovary
0.810 0.189 0.000
I80 Phlebitis and thrombophlebitis
0.806 0.194 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.805 0.195 0.000
A49 Bacterial infection of unspecified site
0.802 0.198 0.000
G30-G32 Other degenerative diseases of the nervous system
0.798 0.202 0.000
K57.1 Diverticular disease of small intestine without perforation or abscess
0.798 0.202 0.000
M47.9 Spondylosis, unspecified
0.796 0.203 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.796 0.204 0.000
M05 Seropositive rheumatoid arthritis
0.796 0.204 0.000
I20 Angina pectoris
0.794 0.206 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.793 0.207 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.793 0.207 0.000
M47.86 Other spondylosis (Lumbar region)
0.792 0.208 0.000
I63.8 Other cerebral infarction
0.791 0.208 0.000
C18.6 Descending colon
0.791 0.209 0.000
H65-H75 Diseases of middle ear and mastoid
0.790 0.210 0.000
J20-J22 Other acute lower respiratory infections
0.789 0.210 0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess
0.789 0.211 0.000
I22 Subsequent myocardial infarction
0.789 0.211 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.786 0.214 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.786 0.214 0.000
C20 Malignant neoplasm of rectum
0.785 0.215 0.000
Z46.6 Fitting and adjustment of urinary device
0.782 0.218 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.780 0.220 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.780 0.220 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.779 0.221 0.000
K51.9 Ulcerative colitis, unspecified
0.779 0.221 0.000
M80-M85 Disorders of bone density and structure
0.778 0.222 0.000
N10-N16 Renal tubulo-interstitial diseases
0.778 0.222 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.777 0.223 0.000
H33 Retinal detachments and breaks
0.776 0.224 0.000
K51.2 Ulcerative (chronic) proctitis
0.773 0.227 0.000
I20.0 Unstable angina
0.773 0.227 0.000
H90.5 Sensorineural hearing loss, unspecified
0.772 0.228 0.000
I21.9 Acute myocardial infarction, unspecified
0.771 0.229 0.000
G70-G73 Diseases of myoneural junction and muscle
0.771 0.229 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.771 0.229 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.771 0.229 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.769 0.231 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.768 0.231 0.000
Z51.0 Radiotherapy session
0.768 0.232 0.000
C15 Malignant neoplasm of oesophagus
0.768 0.232 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.768 0.232 0.000
K58.9 Irritable bowel syndrome without diarrhoea
0.768 0.232 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.767 0.233 0.000
M13 Other arthritis
0.767 0.233 0.000
J95-J99 Other diseases of the respiratory system
0.766 0.234 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.764 0.236 0.000
M70-M79 Other soft tissue disorders
0.763 0.237 0.000
J30-J39 Other diseases of upper respiratory tract
0.762 0.238 0.000
O04 Medical abortion
0.761 0.239 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.760 0.239 0.000
M40-M43 Deforming dorsopathies
0.760 0.240 0.000
I63.9 Cerebral infarction, unspecified
0.760 0.240 0.000
C50-C50 Malignant neoplasm of breast
0.760 0.240 0.000
H60-H62 Diseases of external ear
0.760 0.240 0.000
A41.9 Septicaemia, unspecified
0.759 0.241 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.757 0.243 0.000
K63.3 Ulcer of intestine
0.756 0.244 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.755 0.245 0.000
H80-H83 Diseases of inner ear
0.754 0.246 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.753 0.247 0.000
Z48.0 Attention to surgical dressings and sutures
0.753 0.247 0.000
S50-S59 Injuries to the elbow and forearm
0.750 0.250 0.000
Z43.2 Attention to ileostomy
0.748 0.252 0.000
C18.0 Caecum
0.748 0.252 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.748 0.252 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.747 0.253 0.000
C64-C68 Malignant neoplasms of urinary tract
0.747 0.253 0.000
M10 Gout
0.747 0.253 0.000
Z43.1 Attention to gastrostomy
0.746 0.253 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.745 0.255 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.744 0.256 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.744 0.256 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.743 0.257 0.000
O32.1 Maternal care for breech presentation
0.742 0.258 0.000
H33.0 Retinal detachment with retinal break
0.740 0.260 0.000
O36.8 Maternal care for other specified foetal problems
0.739 0.261 0.000
B25-B34 Other viral diseases
0.739 0.261 0.000
K63.1 Perforation of intestine (nontraumatic)
0.737 0.263 0.000
C56 Malignant neoplasm of ovary
0.736 0.264 0.000
K63.9 Disease of intestine, unspecified
0.735 0.265 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.735 0.265 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.731 0.269 0.000
K59 Other functional intestinal disorders
0.731 0.269 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.731 0.269 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.730 0.270 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.730 0.270 0.000
Z45.1 Adjustment and management of infusion pump
0.729 0.271 0.000
K51.8 Other ulcerative colitis
0.727 0.273 0.000
J90-J94 Other diseases of pleura
0.726 0.274 0.000
C53 Malignant neoplasm of cervix uteri
0.726 0.274 0.000
S01 Open wound of head
0.726 0.274 0.000
Z40 Prophylactic surgery
0.726 0.274 0.000
Z51.2 Other chemotherapy
0.726 0.274 0.000
I80.8 Phlebitis and thrombophlebitis of other sites
0.726 0.274 0.000
H34 Retinal vascular occlusions
0.725 0.275 0.000
M06.0 Seronegative rheumatoid arthritis
0.724 0.276 0.000
O30 Multiple gestation
0.723 0.276 0.000
S00 Superficial injury of head
0.723 0.276 0.000
J34 Other disorders of nose and nasal sinuses
0.723 0.277 0.000
M07 Psoriatic and enteropathic arthropathies
0.722 0.278 0.000
C80 Malignant neoplasm without specification of site
0.721 0.278 0.000
M11 Other crystal arthropathies
0.721 0.279 0.000
K60 Fissure and fistula of anal and rectal regions
0.721 0.279 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.721 0.279 0.000
C78.2 Secondary malignant neoplasm of pleura
0.720 0.280 0.000
Chapter XXII Codes for special purposes
0.720 0.280 0.000
M45 Ankylosing spondylitis
0.719 0.280 0.000
M54.2 Cervicalgia
0.719 0.281 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.718 0.282 0.000
A41.8 Other specified septicaemia
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Z51.9 Medical care, unspecified
0.717 0.283 0.000
Z51.6 Desensitisation to allergens
0.717 0.283 0.000
Z54 Convalescence
0.717 0.283 0.000
Z49 Care involving dialysis
0.717 0.283 0.000
Z44 Fitting and adjustment of external prosthetic device
0.717 0.283 0.000
M91-M94 Chondropathies
0.716 0.283 0.000
M60-M63 Disorders of muscles
0.716 0.283 0.000
M00-M03 Infectious arthropathies
0.716 0.283 0.000
M50 Cervical disk disorders
0.716 0.284 0.000
I08 Multiple valve diseases
0.716 0.284 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.716 0.284 0.000
M48 Other spondylopathies
0.716 0.284 0.000
J60-J70 Lung diseases due to external agents
0.715 0.285 0.000
C18.9 Colon, unspecified
0.715 0.285 0.000
Z43.6 Attention to other artificial openings of urinary tract
0.714 0.286 0.000
G58 Other mononeuropathies
0.713 0.287 0.000
G54 Nerve root and plexus disorders
0.713 0.287 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.713 0.287 0.000
G52 Disorders of other cranial nerves
0.713 0.287 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.712 0.288 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.712 0.288 0.000
O85-O92 Complications predominantly related to the puerperium
0.711 0.289 0.000
K61 Abscess of anal and rectal regions
0.711 0.289 0.000
I67 Other cerebrovascular diseases
0.711 0.289 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.710 0.290 0.000
G83 Other paralytic syndromes
0.709 0.291 0.000
I00-I02 Acute rheumatic fever
0.708 0.291 0.000
S80-S89 Injuries to the knee and lower leg
0.708 0.292 0.000
J22 Unspecified acute lower respiratory infection
0.707 0.293 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.707 0.293 0.000
M14 Arthropathies in other diseases classified elsewhere
0.705 0.295 0.000
M12 Other specific arthropathies
0.705 0.295 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.705 0.295 0.000
M08 Juvenile arthritis
0.705 0.295 0.000
Z46.5 Fitting and adjustment of ileostomy and other intestinal appliances
0.705 0.295 0.000
H43-H45 Disorders of vitreous body and globe
0.705 0.295 0.000
Z52 Donors of organs and tissues
0.704 0.296 0.000
O03 Spontaneous abortion
0.703 0.297 0.000
H93 Other disorders of ear, not elsewhere classified
0.703 0.297 0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere
0.702 0.298 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.702 0.298 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.702 0.298 0.000
I83 Varicose veins of lower extremities
0.702 0.298 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.701 0.299 0.000
Z48.8 Other specified surgical follow-up care
0.701 0.299 0.000
G50 Disorders of trigeminal nerve
0.700 0.299 0.000
N20.1 Calculus of ureter
0.700 0.300 0.000
M86-M90 Other osteopathies
0.699 0.300 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.699 0.301 0.000
M53 Other dorsopathies, not elsewhere classified
0.698 0.302 0.000
B35-B49 Mycoses
0.697 0.303 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.696 0.304 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.696 0.304 0.000
C21 Malignant neoplasm of anus and anal canal
0.696 0.304 0.000
C17 Malignant neoplasm of small intestine
0.696 0.304 0.000
C23 Malignant neoplasm of gallbladder
0.696 0.304 0.000
Z45.9 Adjustment and management of unspecified implanted device
0.695 0.305 0.000
Z45.3 Adjustment and management of implanted hearing device
0.695 0.305 0.000
Z51.8 Other specified medical care
0.695 0.305 0.000
S40-S49 Injuries to the shoulder and upper arm
0.695 0.305 0.000
K57.2 Diverticular disease of large intestine with perforation and abscess
0.695 0.305 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.695 0.305 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.695 0.305 0.000
M54.9 Dorsalgia, unspecified
0.695 0.305 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.694 0.305 0.000
D72 Other disorders of white blood cells
0.694 0.306 0.000
V40-V49 Car occupant injured in transport accident
0.694 0.306 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.694 0.306 0.000
O47 False labour
0.694 0.306 0.000
A49.0 Staphylococcal infection, unspecified
0.694 0.306 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.694 0.306 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.693 0.307 0.000
O45 Premature separation of placenta [abruptio placentae]
0.693 0.307 0.000
O44 Placenta praevia
0.693 0.307 0.000
O43 Placental disorders
0.693 0.307 0.000
O41 Other disorders of amniotic fluid and membranes
0.693 0.307 0.000
O33 Maternal care for known or suspected disproportion
0.693 0.307 0.000
O31 Complications specific to multiple gestation
0.693 0.307 0.000
O40 Polyhydramnios
0.693 0.307 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.692 0.308 0.000
C79.2 Secondary malignant neoplasm of skin
0.691 0.309 0.000
M47.2 Other spondylosis with radiculopathy
0.690 0.310 0.000
M49 Spondylopathies in diseases classified elsewhere
0.689 0.311 0.000
K63.2 Fistula of intestine
0.689 0.311 0.000
K63.4 Enteroptosis
0.688 0.311 0.000
K63.0 Abscess of intestine
0.688 0.311 0.000
G81 Hemiplegia
0.688 0.312 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.688 0.312 0.000
D70 Agranulocytosis
0.687 0.313 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.687 0.313 0.000
M06.8 Other specified rheumatoid arthritis
0.685 0.315 0.000
M06.4 Inflammatory polyarthropathy
0.685 0.315 0.000
M06.3 Rheumatoid nodule
0.685 0.315 0.000
M06.2 Rheumatoid bursitis
0.685 0.315 0.000
M06.1 Adult-onset Still's disease
0.685 0.315 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.683 0.317 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.682 0.318 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.682 0.318 0.000
D68 Other coagulation defects
0.680 0.320 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.680 0.320 0.000
J98 Other respiratory disorders
0.680 0.320 0.000
C18.2 Ascending colon
0.679 0.320 0.000
I95 Hypotension
0.679 0.321 0.000
O04.9 Complete or unspecified, without complication
0.679 0.321 0.000
N60 Benign mammary dysplasia
0.677 0.323 0.000
M51.2 Other specified intervertebral disk displacement
0.677 0.323 0.000
C34 Malignant neoplasm of bronchus and lung
0.676 0.324 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.673 0.327 0.000
C77.3 Axillary and upper limb lymph nodes
0.673 0.327 0.000
G51.9 Disorder of facial nerve, unspecified
0.673 0.327 0.000
G51.8 Other disorders of facial nerve
0.673 0.327 0.000
G51.4 Facial myokymia
0.673 0.327 0.000
G51.3 Clonic hemifacial spasm
0.673 0.327 0.000
G51.2 Melkersson's syndrome
0.673 0.327 0.000
G51.1 Geniculate ganglionitis
0.673 0.327 0.000
S90-S99 Injuries to the ankle and foot
0.673 0.327 0.000
S51 Open wound of forearm
0.672 0.328 0.000
N64 Other disorders of breast
0.671 0.329 0.000
I69 Sequelae of cerebrovascular disease
0.671 0.329 0.000
M46 Other inflammatory spondylopathies
0.671 0.329 0.000
M54.8 Other dorsalgia
0.670 0.330 0.000
M54.6 Pain in thoracic spine
0.670 0.330 0.000
M54.4 Lumbago with sciatica
0.670 0.330 0.000
M54.0 Panniculitis affecting regions of neck and back
0.670 0.330 0.000
M54.1 Radiculopathy
0.670 0.330 0.000
J90 Pleural effusion, not elsewhere classified
0.670 0.330 0.000
Z46.8 Fitting and adjustment of other specified devices
0.669 0.331 0.000
H53-H54 Visual disturbances and blindness
0.669 0.331 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.669 0.331 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.669 0.331 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.669 0.331 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.669 0.331 0.000
Z43.9 Attention to unspecified artificial opening
0.668 0.332 0.000
Z43.8 Attention to other artificial openings
0.668 0.332 0.000
Z43.7 Attention to artificial vagina
0.668 0.332 0.000
Z43.5 Attention to cyctostomy
0.668 0.332 0.000
Z43.4 Attention to other artificial openings of digestive tract
0.668 0.332 0.000
Z43.0 Attention to tracheostomy
0.668 0.332 0.000
D00-D09 In situ neoplasms
0.668 0.332 0.000
O70 Perineal laceration during delivery
0.668 0.332 0.000
O36.5 Maternal care for poor foetal growth
0.667 0.333 0.000
C54 Malignant neoplasm of corpus uteri
0.667 0.333 0.000
M47.1 Other spondylosis with myelopathy
0.666 0.334 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.666 0.334 0.000
M51.9 Intervertebral disk disorder, unspecified
0.666 0.334 0.000
V10-V19 Pedal cyclist injured in transport accident
0.665 0.334 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.665 0.335 0.000
V20-V29 Motorcycle rider injured in transport accident
0.664 0.336 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.663 0.337 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.663 0.337 0.000
I23 Certain current complications following acute myocardial infarction
0.662 0.338 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.661 0.338 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.660 0.340 0.000
K55.0 Acute vascular disorders of intestine
0.660 0.340 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.659 0.340 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.659 0.340 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.659 0.340 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.659 0.340 0.000
D60-D64 Aplastic and other anaemias
0.659 0.341 0.000
C16 Malignant neoplasm of stomach
0.659 0.341 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.659 0.341 0.000
N25-N29 Other disorders of kidney and ureter
0.658 0.342 0.000
Y86 Sequelae of other accidents
0.658 0.342 0.000
S10-S19 Injuries to the neck
0.657 0.342 0.000
Z33 Pregnant state, incidental
0.657 0.342 0.000
C18.7 Sigmoid colon
0.656 0.344 0.000
G93 Other disorders of brain
0.656 0.344 0.000
O73 Retained placenta and membranes, without haemorrhage
0.656 0.344 0.000
H92 Otalgia and effusion of ear
0.656 0.344 0.000
I05 Rheumatic mitral valve diseases
0.655 0.344 0.000
D55-D59 Haemolytic anaemias
0.655 0.345 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.655 0.345 0.000
G30 Alzheimer's disease
0.655 0.345 0.000
B99-B99 Other infectious diseases
0.654 0.346 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.654 0.346 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.654 0.346 0.000
B65-B83 Helminthiases
0.654 0.346 0.000
B50-B64 Protozoal diseases
0.654 0.346 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.654 0.346 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.654 0.346 0.000
A80-A89 Viral infections of the central nervous system
0.654 0.346 0.000
A75-A79 Rickettsioses
0.654 0.346 0.000
A70-A74 Other diseases caused by chlamydiae
0.654 0.346 0.000
A65-A69 Other spirochaetal diseases
0.654 0.346 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.654 0.346 0.000
A20-A28 Certain zoonotic bacterial diseases
0.654 0.346 0.000
A15-A19 Tuberculosis
0.654 0.346 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.654 0.346 0.000
I81 Portal vein thrombosis
0.654 0.346 0.000
Z42 Follow-up care involving plastic surgery
0.653 0.346 0.000
M72 Fibroblastic disorders
0.653 0.347 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.653 0.347 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.653 0.347 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.653 0.347 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.653 0.347 0.000
C51 Malignant neoplasm of vulva
0.653 0.347 0.000
C58 Malignant neoplasm of placenta
0.653 0.347 0.000
C52 Malignant neoplasm of vagina
0.653 0.347 0.000
K59.8 Other specified functional intestinal disorders
0.652 0.348 0.000
M47.82 Other spondylosis (Cervical region)
0.652 0.348 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.651 0.349 0.000
G12 Spinal muscular atrophy and related syndromes
0.651 0.349 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.651 0.349 0.000
N20.9 Urinary calculus, unspecified
0.651 0.349 0.000
I86 Varicose veins of other sites
0.650 0.349 0.000
M50.1 Cervical disk disorder with radiculopathy
0.650 0.350 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.650 0.350 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.650 0.350 0.000
J34.2 Deviated nasal septum
0.650 0.350 0.000
X60-X84 Intentional self-harm
0.650 0.350 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.650 0.350 0.000
I62 Other nontraumatic intracranial haemorrhage
0.649 0.351 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.649 0.351 0.000
H55-H59 Other disorders of eye and adnexa
0.649 0.351 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.648 0.351 0.000
O80-O84 Delivery
0.648 0.352 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.647 0.352 0.000
M54.55 Low back pain (Thoracolumbar region)
0.647 0.353 0.000
M54.54 Low back pain-Thoracic
0.647 0.353 0.000
M54.53 Low back pain-Cervicothoracic
0.647 0.353 0.000
M54.52 Low back pain-Cervical
0.647 0.353 0.000
M54.51 Low back pain-Occipit-atl-axl
0.647 0.353 0.000
M54.50 Low back pain (Multiple sites in spine)
0.647 0.353 0.000
C18.8 Overlapping lesion of colon
0.646 0.353 0.000
C18.5 Splenic flexure
0.646 0.353 0.000
C18.3 Hepatic flexure
0.646 0.353 0.000
C18.1 Appendix
0.646 0.353 0.000
M65-M68 Disorders of synovium and tendon
0.646 0.354 0.000
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess
0.646 0.354 0.000
K57.5 Diverticular disease of both small and large intestine without perforation or abscess
0.646 0.354 0.000
K57.4 Diverticular disease of both small and large intestine with perforation and abscess
0.646 0.354 0.000
K57.0 Diverticular disease of small intestine with perforation and abscess
0.646 0.354 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.646 0.354 0.000
K55.2 Angiodysplasia of colon
0.645 0.354 0.000
D10-D36 Benign neoplasms
0.643 0.357 0.000
C32 Malignant neoplasm of larynx
0.642 0.357 0.000
G82 Paraplegia and tetraplegia
0.642 0.357 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.642 0.358 0.000
Y35-Y36 Legal intervention and operations of war
0.642 0.358 0.000
Y10-Y34 Event of undetermined intent
0.642 0.358 0.000
Y00-Y09 Assault
0.642 0.358 0.000
X85-X99 Assault
0.642 0.358 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.642 0.358 0.000
X50-X57 Overexertion, travel and privation
0.642 0.358 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.642 0.358 0.000
X30-X39 Exposure to forces of nature
0.642 0.358 0.000
X20-X29 Contact with venomous animals and plants
0.642 0.358 0.000
X10-X19 Contact with heat and hot substances
0.642 0.358 0.000
X00-X09 Exposure to smoke, fire and flames
0.642 0.358 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.642 0.358 0.000
W75-W84 Other accidental threats to breathing
0.642 0.358 0.000
W65-W74 Accidental drowning and submersion
0.642 0.358 0.000
W50-W64 Exposure to animate mechanical forces
0.642 0.358 0.000
V98-V99 Other and unspecified transport accidents
0.642 0.358 0.000
V95-V97 Air and space transport accidents
0.642 0.358 0.000
V90-V94 Water transport accidents
0.642 0.358 0.000
V80-V89 Other land transport accidents
0.642 0.358 0.000
V70-V79 Bus occupant injured in transport accident
0.642 0.358 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.642 0.358 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.642 0.358 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.642 0.358 0.000
V01-V09 Pedestrian injured in transport accident
0.642 0.358 0.000
W20-W49 Exposure to inanimate mechanical forces
0.642 0.358 0.000
O62 Abnormalities of forces of labour
0.642 0.358 0.000
Z46.9 Fitting and adjustment of other unspecified device
0.641 0.359 0.000
Z46.7 Fitting and adjustment of orthopaedic device
0.641 0.359 0.000
Z46.4 Fitting and adjustment of orthodontic device
0.641 0.359 0.000
Z46.3 Fitting and adjustment of dental prosthetic device
0.641 0.359 0.000
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses
0.641 0.359 0.000
Z46.1 Fitting and adjustment of hearing aid
0.641 0.359 0.000
Z46.0 Fitting and adjustment of spectacles and contact lenses
0.641 0.359 0.000
G57.9 Mononeuropathy of lower limb, unspecified
0.641 0.359 0.000
G57.8 Other mononeuropathies of lower limb
0.641 0.359 0.000
G57.5 Tarsal tunnel syndrome
0.641 0.359 0.000
G57.4 Lesion of medial popliteal nerve
0.641 0.359 0.000
G57.3 Lesion of lateral popliteal nerve
0.641 0.359 0.000
G57.2 Lesion of femoral nerve
0.641 0.359 0.000
G57.1 Meralgia paraesthetica
0.641 0.359 0.000
G57.0 Lesion of sciatic nerve
0.641 0.359 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.639 0.361 0.000
O00 Ectopic pregnancy
0.639 0.361 0.000
A49.1 Streptococcal infection, unspecified
0.639 0.361 0.000
H33.3 Retinal breaks without detachment
0.638 0.362 0.000
B15-B19 Viral hepatitis
0.638 0.362 0.000
M54.3 Sciatica
0.638 0.362 0.000
J34.3 Hypertrophy of nasal turbinates
0.637 0.363 0.000
T79-T79 Certain early complications of trauma
0.636 0.364 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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