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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75891265
log Bayes Factor = 11.481
Chromosome 6   position 33,185,578  (GRCh37) Explore rs75891265 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.001 0.999
E10.3 With ophthalmic complications
0.000 0.001 0.999
E11 Non-insulin-dependent diabetes mellitus
0.000 0.002 0.998
E11.4 With neurological complications
0.000 0.020 0.980
E11.3 With ophthalmic complications
0.000 0.024 0.976
E10.1 With ketoacidosis
0.000 0.037 0.963
E10.5 With peripheral circulatory complications
0.000 0.075 0.925
E10.2 With renal complications
0.000 0.095 0.905
E16.2 Hypoglycaemia, unspecified
0.000 0.110 0.890
E16 Other disorders of pancreatic internal secretion
0.000 0.114 0.886
E14 Unspecified diabetes mellitus
0.000 0.117 0.883
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.117 0.883
E11.1 With ketoacidosis
0.000 0.118 0.882
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.118 0.882
E10.4 With neurological complications
0.000 0.125 0.875
E11.2 With renal complications
0.000 0.160 0.840
E11.6 With other specified complications
0.000 0.221 0.779
E14.3 With ophthalmic complications
0.000 0.224 0.776
E11.5 With peripheral circulatory complications
0.000 0.235 0.765
E10.8 With unspecified complications
0.000 0.238 0.762
E50-E64 Other nutritional deficiencies
0.000 0.254 0.746
K90.0 Coeliac disease
0.000 0.273 0.727
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.284 0.716
E11.0 With coma
0.000 0.301 0.699
E14.9 Without complications
0.000 0.310 0.690
E10.0 With coma
0.000 0.319 0.681
E16.1 Other hypoglycaemia
0.000 0.330 0.669
E11.8 With unspecified complications
0.000 0.340 0.660
E53 Deficiency of other B group vitamins
0.000 0.355 0.645
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.365 0.635
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.365 0.635
E16.4 Abnormal secretion of gastrin
0.000 0.365 0.635
E16.3 Increased secretion of glucagon
0.000 0.365 0.635
E14.8 With unspecified complications
0.000 0.367 0.633
E14.7 With multiple complications
0.000 0.367 0.633
E14.6 With other specified complications
0.000 0.367 0.633
E14.5 With peripheral circulatory complications
0.000 0.367 0.633
E14.4 With neurological complications
0.000 0.367 0.633
E14.2 Withrenal complications
0.000 0.367 0.633
E14.1 With ketoacidosis
0.000 0.367 0.633
E14.0 With coma
0.000 0.367 0.633
E15 Nondiabetic hypoglycaemic coma
0.000 0.367 0.633
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.373 0.627
E53.8 Deficiency of other specified B group vitamins
0.000 0.409 0.591
E55 Vitamin D deficiency
0.000 0.421 0.579
E40-E46 Malnutrition
0.000 0.445 0.554
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.465 0.535
E63 Other nutritional deficiencies
0.000 0.465 0.535
E56 Other vitamin deficiencies
0.000 0.465 0.535
E51 Thiamine deficiency
0.000 0.465 0.535
E50 Vitamin A deficiency
0.000 0.465 0.535
E60 Dietary zinc deficiency
0.000 0.465 0.535
E59 Dietary selenium deficiency
0.000 0.465 0.535
E58 Dietary calcium deficiency
0.000 0.465 0.535
E54 Ascorbic acid deficiency
0.000 0.465 0.535
E52 Niacin deficiency [pellagra]
0.000 0.465 0.535
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E13 Other specified diabetes mellitus
0.001 0.488 0.511
E61 Deficiency of other nutrient elements
0.000 0.513 0.487
E20-E35 Disorders of other endocrine glands
0.000 0.522 0.478
E53.1 Pyridoxine deficiency
0.000 0.538 0.462
E53.0 Riboflavin deficiency
0.000 0.538 0.462
E55.9 Vitamin D deficiency, unspecified
0.000 0.540 0.460
E34 Other endocrine disorders
0.000 0.573 0.427
E55.0 Rickets, active
0.000 0.585 0.415
E53.9 Vitamin B deficiency, unspecified
0.000 0.601 0.399
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.602 0.398
E45 Retarded development following protein-energy malnutrition
0.000 0.602 0.398
E43 Unspecified severe protein-energy malnutrition
0.000 0.602 0.398
E42 Marasmic kwashiorkor
0.000 0.602 0.398
E41 Nutritional marasmus
0.000 0.602 0.398
E40 Kwashiorkor
0.000 0.602 0.398
E20 Hypoparathyroidism
0.000 0.608 0.392
E65-E68 Obesity and other hyperalimentation
0.000 0.613 0.387
E50.9 Vitamin A deficiency, unspecified
0.000 0.616 0.383
E50.8 Other manifestations of vitamin A deficiency
0.000 0.616 0.383
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.616 0.383
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.616 0.383
E50.5 Vitamin A deficiency with night blindness
0.000 0.616 0.383
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.616 0.383
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.616 0.383
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.616 0.383
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.616 0.383
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.616 0.383
E51.9 Thiamine deficiency, unspecified
0.000 0.616 0.383
E51.8 Other manifestations of thiamine deficiency
0.000 0.616 0.383
E51.2 Wernicke's encephalopathy
0.000 0.616 0.383
E51.1 Beriberi
0.000 0.616 0.383
E56.9 Vitamin deficiency, unspecified
0.000 0.616 0.383
E56.8 Deficiency of other vitamins
0.000 0.616 0.383
E56.1 Deficiency of vitamin K
0.000 0.616 0.383
E56.0 Deficiency of vitamin E
0.000 0.616 0.383
E63.9 Nutritional deficiency, unspecified
0.000 0.616 0.383
E63.8 Other specified nutritional deficiencies
0.000 0.616 0.383
E63.1 Imbalance of constituents of food intake
0.000 0.616 0.383
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.616 0.383
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.616 0.383
E64.8 Sequelae of other nutritional deficiencies
0.000 0.616 0.383
E64.3 Sequelae of rickets
0.000 0.616 0.383
E64.2 Sequelae of vitamin C deficiency
0.000 0.616 0.383
E64.1 Sequelae of vitamin A deficiency
0.000 0.616 0.383
E64.0 Sequelae of protein-energy malnutrition
0.000 0.616 0.383
E34.9 Endocrine disorder, unspecified
0.000 0.620 0.380
E22 Hyperfunction of pituitary gland
0.000 0.620 0.380
E13.8 With unspecified complications
0.001 0.633 0.367
E13.7 With multiple complications
0.001 0.633 0.367
E13.6 With other specified complications
0.001 0.633 0.367
E13.5 With peripheral circulatory complications
0.001 0.633 0.367
E13.4 With neurological complications
0.001 0.633 0.367
E13.3 With ophthalmic complications
0.001 0.633 0.367
E13.2 With renal complications
0.001 0.633 0.367
E13.1 With ketoacidosis
0.001 0.633 0.367
E13.0 With coma
0.001 0.633 0.367
E61.9 Deficiency of nutrient element, unspecified
0.000 0.651 0.349
E61.8 Deficiency of other specified nutrient elements
0.000 0.651 0.349
E61.7 Deficiency of multiple nutrient elements
0.000 0.651 0.349
E61.6 Vanadium deficiency
0.000 0.651 0.349
E61.5 Molybdenum deficiency
0.000 0.651 0.349
E61.4 Chromium deficiency
0.000 0.651 0.349
E61.3 Manganese deficiency
0.000 0.651 0.349
E61.2 Magnesium deficiency
0.000 0.651 0.349
E61.0 Copper deficiency
0.000 0.651 0.349
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.657 0.343
E32 Diseases of thymus
0.000 0.657 0.343
E31 Polyglandular dysfunction
0.000 0.657 0.343
E30 Disorders of puberty, not elsewhere classified
0.000 0.657 0.343
E25 Adrenogenital disorders
0.000 0.657 0.343
K90 Intestinal malabsorption
0.000 0.659 0.341
E20.9 Hypoparathyroidism, unspecified
0.000 0.669 0.331
E34.0 Carcinoid syndrome
0.000 0.669 0.331
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.670 0.330
E00-E07 Disorders of thyroid gland
0.000 0.673 0.327
E46 Unspecified protein-energy malnutrition
0.000 0.680 0.319
E70-E90 Metabolic disorders
0.000 0.681 0.319
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.687 0.313
E83 Disorders of mineral metabolism
0.000 0.691 0.309
E34.8 Other specified endocrine disorders
0.000 0.692 0.308
E34.5 Androgen resistance syndrome
0.000 0.694 0.306
E34.4 Constitutional tall stature
0.000 0.694 0.306
E34.3 Short stature, not elsewhere classified
0.000 0.694 0.306
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.694 0.306
E34.1 Other hypersecretion of intestinal hormones
0.000 0.694 0.306
E27 Other disorders of adrenal gland
0.000 0.696 0.304
E28 Ovarian dysfunction
0.000 0.698 0.301
E61.1 Iron deficiency
0.000 0.699 0.301
E83.1 Disorders of iron metabolism
0.000 0.699 0.301
E26 Hyperaldosteronism
0.000 0.699 0.301
E29 Testicular dysfunction
0.000 0.706 0.294
K90.9 Intestinal malabsorption, unspecified
0.000 0.714 0.286
E44.1 Mild protein-energy malnutrition
0.000 0.715 0.285
E44.0 Moderate protein-energy malnutrition
0.000 0.715 0.285
E22.0 Acromegaly and pituitary gigantism
0.000 0.717 0.283
E20.8 Other hypoparathyroidism
0.000 0.719 0.281
E20.1 Pseudohypoparathyroidism
0.000 0.719 0.281
E20.0 Idiopathic hypoparathyroidism
0.000 0.719 0.281
E83.4 Disorders of magnesium metabolism
0.000 0.722 0.278
E67 Other hyperalimentation
0.000 0.723 0.277
E68 Sequelae of hyperalimentation
0.000 0.723 0.277
E04 Other non-toxic goitre
0.000 0.723 0.277
E21.3 Hyperparathyroidism, unspecified
0.000 0.727 0.273
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.727 0.272
E22.8 Other hyperfunction of pituitary gland
0.000 0.727 0.272
E65 Localised adiposity
0.000 0.742 0.258
E06 Thyroiditis
0.000 0.744 0.256
E27.1 Primary adrenocortical insufficiency
0.000 0.745 0.254
E22.1 Hyperprolactinaemia
0.000 0.746 0.254
E25.9 Adrenogenital disorder, unspecified
0.000 0.754 0.246
E25.8 Other adrenogenital disorders
0.000 0.754 0.246
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.754 0.246
E30.9 Disorder of puberty, unspecified
0.000 0.754 0.246
E30.8 Other disorders of puberty
0.000 0.754 0.246
E30.1 Precocious puberty
0.000 0.754 0.246
E30.0 Delayed puberty
0.000 0.754 0.246
E31.9 Polyglandular dysfunction, unspecified
0.000 0.754 0.246
E31.8 Other polyglandular dysfunction
0.000 0.754 0.246
E31.1 Polyglandular hyperfunction
0.000 0.754 0.246
E31.0 Autoimmune polyglandular failure
0.000 0.754 0.246
E32.9 Disease of thymus, unspecified
0.000 0.754 0.246
E32.8 Other diseases of thymus
0.000 0.754 0.246
E32.1 Abscess of thymus
0.000 0.754 0.246
E32.0 Persistent hyperplasia of thymus
0.000 0.754 0.246
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.754 0.246
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.754 0.246
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.754 0.246
K90.8 Other intestinal malabsorption
0.000 0.755 0.245
K90.3 Pancreatic steatorrhoea
0.000 0.755 0.245
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.755 0.245
K90.1 Tropical sprue
0.000 0.755 0.245
E88 Other metabolic disorders
0.000 0.757 0.243
E04.2 Non-toxic multinodular goitre
0.000 0.762 0.238
E21.4 Other specified disorders of parathyroid gland
0.000 0.763 0.237
E21.2 Other hyperparathyroidism
0.000 0.763 0.237
E21.0 Primary hyperparathyroidism
0.000 0.763 0.236
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.765 0.234
E00 Congenital iodine-deficiency syndrome
0.000 0.765 0.234
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.765 0.234
E28.3 Primary ovarian failure
0.000 0.770 0.230
E84 Cystic fibrosis
0.000 0.771 0.229
E79 Disorders of purine and pyrimidine metabolism
0.000 0.771 0.229
E77 Disorders of glycoprotein metabolism
0.000 0.771 0.229
E76 Disorders of glycosaminoglycan metabolism
0.000 0.771 0.229
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.771 0.229
E72 Other disorders of amino-acid metabolism
0.000 0.771 0.229
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.771 0.229
E70 Disorders of aromatic amino-acid metabolism
0.000 0.771 0.229
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.771 0.229
E27.9 Disorder of adrenal gland, unspecified
0.000 0.772 0.228
E04.1 Non-toxic single thyroid nodule
0.000 0.772 0.228
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.773 0.227
E24 Cushing's syndrome
0.001 0.778 0.222
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.778 0.222
E83.8 Other disorders of mineral metabolism
0.000 0.778 0.222
E83.2 Disorders of zinc metabolism
0.000 0.778 0.222
E83.0 Disorders of copper metabolism
0.000 0.778 0.222
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.782 0.218
E74 Other disorders of carbohydrate metabolism
0.000 0.782 0.218
E27.5 Adrenomedullary hyperfunction
0.000 0.782 0.218
E27.0 Other adrenocortical overactivity
0.000 0.782 0.218
E28.9 Ovarian dysfunction, unspecified
0.000 0.784 0.216
E28.8 Other ovarian dysfunction
0.000 0.784 0.216
E28.1 Androgen excess
0.000 0.784 0.216
E28.0 Oestrogen excess
0.000 0.784 0.216
E85 Amyloidosis
0.000 0.784 0.216
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.784 0.216
E26.8 Other hyperaldosteronism
0.000 0.784 0.216
E26.1 Secondary hyperaldosteronism
0.000 0.784 0.216
E83.3 Disorders of phosphorus metabolism
0.000 0.785 0.215
E23 Hypofunction and other disorders of pituitary gland
0.000 0.787 0.213
E04.0 Non-toxic diffuse goitre
0.000 0.788 0.212
E29.9 Testicular dysfunction, unspecified
0.000 0.789 0.211
E29.8 Other testicular dysfunction
0.000 0.789 0.211
E29.0 Testicular hyperfunction
0.000 0.789 0.211
E26.0 Primary hyperaldosteronism
0.000 0.792 0.208
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.792 0.208
E27.2 Addisonian crisis
0.000 0.801 0.199
E67.8 Other specified hyperalimentation
0.000 0.801 0.199
E67.3 Hypervitaminosis D
0.000 0.801 0.199
E67.2 Megavitamin-B6 syndrome
0.000 0.801 0.199
E67.1 Hypercarotenaemia
0.000 0.801 0.199
E67.0 Hypervitaminosis A
0.000 0.801 0.199
E06.3 Autoimmune thyroiditis
0.000 0.801 0.199
E04.8 Other specified non-toxic goitre
0.000 0.801 0.198
E73 Lactose intolerance
0.000 0.806 0.193
E06.9 Thyroiditis, unspecified
0.000 0.807 0.193
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.809 0.191
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.811 0.188
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.811 0.188
E27.8 Other specified disorders of adrenal gland
0.000 0.811 0.188
E26.9 Hyperaldosteronism, unspecified
0.000 0.815 0.185
E06.5 Other chronic thyroiditis
0.000 0.816 0.184
E06.4 Drug-induced thyroiditis
0.000 0.816 0.184
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.816 0.184
E06.1 Subacute thyroiditis
0.000 0.816 0.184
E06.0 Acute thyroiditis
0.000 0.816 0.184
E89.3 Postprocedural hypopituitarism
0.000 0.818 0.182
E88.9 Metabolic disorder, unspecified
0.000 0.825 0.174
E88.8 Other specified metabolic disorders
0.000 0.825 0.174
E88.3 Tumour lysis syndrome
0.000 0.825 0.174
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.825 0.174
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.828 0.171
E89.2 Postprocedural hypoparathyroidism
0.000 0.830 0.170
E80.4 Gilbert's syndrome
0.000 0.830 0.170
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.832 0.168
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.832 0.168
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.832 0.168
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.832 0.168
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.832 0.168
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.832 0.168
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.832 0.168
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.832 0.168
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.836 0.164
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.836 0.164
E70.3 Albinism
0.000 0.836 0.164
E70.2 Disorders of tyrosine metabolism
0.000 0.836 0.164
E70.1 Other hyperphenylalaninaemias
0.000 0.836 0.164
E70.0 Classical phenylketonuria
0.000 0.836 0.164
E71.3 Disorders of fatty-acid metabolism
0.000 0.836 0.164
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.836 0.164
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.836 0.164
E71.0 Maple-syrup-urine disease
0.000 0.836 0.164
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.836 0.164
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.836 0.164
E72.5 Disorders of glycine metabolism
0.000 0.836 0.164
E72.4 Disorders of ornithine metabolism
0.000 0.836 0.164
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.836 0.164
E72.2 Disorders of urea cycle metabolism
0.000 0.836 0.164
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.836 0.164
E72.0 Disorders of amino-acid transport
0.000 0.836 0.164
E75.6 Lipid storage disorder, unspecified
0.000 0.836 0.164
E75.5 Other lipid storage disorders
0.000 0.836 0.164
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.836 0.164
E75.3 Sphingolipidosis, unspecified
0.000 0.836 0.164
E75.2 Other sphingolipidosis
0.000 0.836 0.164
E75.1 Other gangliosidosis
0.000 0.836 0.164
E75.0 GM2 gangliosidosis
0.000 0.836 0.164
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.836 0.164
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.836 0.164
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.836 0.164
E76.2 Other mucopolysaccharidoses
0.000 0.836 0.164
E76.1 Mucopolysaccharidosis, type II
0.000 0.836 0.164
E76.0 Mucopolysaccharidosis, type I
0.000 0.836 0.164
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.836 0.164
E77.8 Other disorders of glycoprotein metabolism
0.000 0.836 0.164
E77.1 Defects in glycoprotein degradation
0.000 0.836 0.164
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.836 0.164
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.836 0.164
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.836 0.164
E79.1 Lesch-Nyhan syndrome
0.000 0.836 0.164
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.836 0.164
E84.9 Cystic fibrosis, unspecified
0.000 0.836 0.164
E84.8 Cystic fibrosis with other manifestations
0.000 0.836 0.164
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.836 0.164
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.836 0.164
E13.9 Without complications
0.002 0.837 0.161
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.837 0.163
E80.5 Crigler-Najjar syndrome
0.000 0.837 0.163
E80.3 Defects of catalase and peroxydase
0.000 0.837 0.163
E80.2 Other porphyria
0.000 0.837 0.163
E80.1 Porphyria cutanea tarda
0.000 0.837 0.163
E80.0 Hereditary erythropoietic porphyria
0.000 0.837 0.163
E29.1 Testicular hypofunction
0.000 0.838 0.162
E07 Other disorders of thyroid
0.000 0.840 0.160
E24.8 Other Cushing's syndrome
0.001 0.840 0.159
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.001 0.840 0.159
E24.3 Ectopic ACTH syndrome
0.001 0.840 0.159
E24.2 Drug-induced Cushing's syndrome
0.001 0.840 0.159
E24.1 Nelson's syndrome
0.001 0.840 0.159
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.843 0.156
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.843 0.156
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.843 0.156
E74.2 Disorders of galactose metabolism
0.000 0.843 0.156
E74.1 Disorders of fructose metabolism
0.000 0.843 0.156
E74.0 Glycogen storage disease
0.000 0.843 0.156
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.843 0.156
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.843 0.156
E89.5 Postprocedural testicular hypofunction
0.000 0.843 0.156
E89.1 Postprocedural hypoinsulinaemia
0.000 0.843 0.156
E23.7 Disorder of pituitary gland, unspecified
0.000 0.844 0.155
E85.8 Other amyloidosis
0.000 0.845 0.155
E85.3 Secondary systemic amyloidosis
0.000 0.845 0.155
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.845 0.155
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.845 0.155
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.845 0.155
E80.6 Other disorders of bilirubin metabolism
0.000 0.847 0.153
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.847 0.153
E23.1 Drug-induced hypopituitarism
0.000 0.847 0.153
E85.4 Organ-limited amyloidosis
0.000 0.850 0.150
E28.2 Polycystic ovarian syndrome
0.000 0.850 0.150
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.851 0.149
E85.9 Amyloidosis, unspecified
0.000 0.851 0.148
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.854 0.145
E89.4 Postprocedural ovarian failure
0.000 0.857 0.143
E73.8 Other lactose intolerance
0.000 0.861 0.139
E73.1 Secondary lactase deficiency
0.000 0.861 0.139
E73.0 Congenital lactase deficiency
0.000 0.861 0.139
E23.6 Other disorders of pituitary gland
0.000 0.862 0.138
E88.2 Lipomatosis, not elsewhere classified
0.000 0.863 0.137
E04.9 Non-toxic goitre, unspecified
0.000 0.865 0.135
E23.2 Diabetes insipidus
0.000 0.870 0.129
E83.5 Disorders of calcium metabolism
0.000 0.878 0.121
E24.0 Pituitary-dependent Cushing's disease
0.001 0.884 0.115
E07.1 Dyshormogenetic goitre
0.000 0.885 0.115
E07.0 Hypersecretion of calcitonin
0.000 0.885 0.115
E24.9 Cushing's syndrome, unspecified
0.001 0.886 0.113
E07.8 Other specified disorders of thyroid
0.000 0.891 0.109
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.891 0.109
E73.9 Lactose intolerance, unspecified
0.000 0.896 0.103
E89.0 Postprocedural hypothyroidism
0.000 0.897 0.103
M31.6 Other giant cell arteritis
0.102 0.898 0.000
E03 Other hypothyroidism
0.000 0.899 0.101
M31.3 Wegener's granulomatosis
0.099 0.901 0.000
E23.0 Hypopituitarism
0.000 0.902 0.098
M31 Other necrotising vasculopathies
0.097 0.903 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.916 0.084
E66 Obesity
0.000 0.916 0.084
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.921 0.079
E05.5 Thyroid crisis or storm
0.000 0.922 0.078
E05.4 Thyrotoxicosis factitia
0.000 0.922 0.078
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.922 0.078
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.922 0.078
E87.1 Hypo-osmolality and hyponatraemia
0.000 0.925 0.075
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.926 0.074
E03.5 Myxoedema coma
0.000 0.928 0.072
E03.4 Atrophy of thyroid (acquired)
0.000 0.928 0.072
E03.3 Postinfectious hypothyroidism
0.000 0.928 0.072
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.928 0.072
E03.1 Congenital hypothyroidism without goitre
0.000 0.928 0.072
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.928 0.072
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.071 0.929 0.000
R20.2 Paraesthesia of skin
0.070 0.930 0.000
M31.9 Necrotising vasculopathy, unspecified
0.069 0.930 0.000
M31.8 Other specified necrotising vasculopathies
0.069 0.930 0.000
M31.7 Microscopic polyangiitis
0.069 0.930 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.069 0.930 0.000
M31.2 Lethal midline granuloma
0.069 0.930 0.000
M31.1 Thrombotic microangiopathy
0.069 0.930 0.000
M31.0 Hypersensitivity angiitis
0.069 0.930 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.931 0.069
K90-K93 Other diseases of the digestive system
0.000 0.933 0.067
E05.8 Other thyrotoxicosis
0.000 0.934 0.066
J98.1 Pulmonary collapse
0.064 0.936 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.939 0.061
E87.4 Mixed disorder of acid-base balance
0.000 0.939 0.060
E66.1 Drug-induced obesity
0.000 0.940 0.060
E66.0 Obesity due to excess calories
0.000 0.942 0.058
E86 Volume depletion
0.000 0.942 0.058
E07.9 Disorder of thyroid, unspecified
0.000 0.944 0.055
R20 Disturbances of skin sensation
0.055 0.945 0.000
E03.8 Other specified hypothyroidism
0.000 0.945 0.054
E87.5 Hyperkalaemia
0.000 0.946 0.054
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.947 0.053
E87.3 Alkalosis
0.000 0.948 0.052
R20.8 Other and unspecified disturbances of skin sensation
0.050 0.950 0.000
E11.9 Without complications
0.000 0.951 0.049
E87.0 Hyperosmolality and hypernatraemia
0.000 0.951 0.049
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.952 0.048
R20.3 Hyperaesthesia
0.045 0.955 0.000
E78.4 Other hyperlipidaemia
0.000 0.955 0.045
R20.1 Hypoaesthesia of skin
0.042 0.958 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.959 0.041
E78.1 Pure hyperglyceridaemia
0.000 0.960 0.039
E78.6 Lipoprotein deficiency
0.000 0.962 0.038
E78.3 Hyperchylomicronaemia
0.000 0.962 0.038
R20.0 Anaesthesia of skin
0.036 0.964 0.000
E78.2 Mixed hyperlipidaemia
0.000 0.965 0.035
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.965 0.035
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.965 0.035
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.965 0.034
K93.1 Megacolon in Chagas' disease
0.000 0.965 0.034
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.965 0.034
E87.2 Acidosis
0.000 0.966 0.034
K91.4 Colostomy and enterostomy malfunction
0.000 0.967 0.033
K91.1 Postgastric surgery syndromes
0.000 0.970 0.030
K91.9 Postprocedural disorder of digestive system, unspecified
0.000 0.971 0.029
K91.5 Postcholecystectomy syndrome
0.000 0.971 0.029
K91.2 Postsurgical malabsorption, not elsewhere classified
0.000 0.971 0.029
E78.8 Other disorders of lipoprotein metabolism
0.000 0.972 0.027
K92 Other diseases of digestive system
0.000 0.974 0.026
T51.0 Ethanol
0.000 0.975 0.025
E66.8 Other obesity
0.000 0.975 0.024
E87.7 Fluid overload
0.000 0.976 0.024
K92.9 Disease of digestive system, unspecified
0.000 0.978 0.021
K92.8 Other specified diseases of digestive system
0.000 0.979 0.021
E05.9 Thyrotoxicosis, unspecified
0.000 0.979 0.021
K91.3 Postoperative intestinal obstruction
0.000 0.980 0.020
K92.0 Haematemesis
0.000 0.980 0.020
N81.2 Incomplete uterovaginal prolapse
0.019 0.981 0.000
H36.0 Diabetic retinopathy
0.000 0.982 0.018
G56.0 Carpal tunnel syndrome
0.000 0.983 0.017
T51 Toxic effect of alcohol
0.000 0.984 0.016
T51.9 Alcohol, unspecified
0.000 0.987 0.013
E87.6 Hypokalaemia
0.000 0.987 0.013
D12.8 Rectum
0.000 0.988 0.012
T51.8 Other alcohols
0.000 0.988 0.012
T51.3 Fusel oil
0.000 0.988 0.012
T51.2 2-Propanol
0.000 0.988 0.012
T51.1 Methanol
0.000 0.988 0.012
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.000 0.988 0.011
J43.9 Emphysema, unspecified
0.000 0.990 0.010
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.010 0.990 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.009 0.991 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.009 0.991 0.000
J98 Other respiratory disorders
0.009 0.991 0.000
Q61 Cystic kidney disease
0.009 0.991 0.000
Q61.2 Polycystic kidney, adult type
0.009 0.991 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.008 0.992 0.000
Q60-Q64 Congenital malformations of the urinary system
0.008 0.992 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.008 0.992 0.000
Q43 Other congenital malformations of intestine
0.008 0.992 0.000
C34.9 Bronchus or lung, unspecified
0.000 0.992 0.008
H21.8 Other specified disorders of iris and ciliary body
0.008 0.992 0.000
Q50-Q56 Congenital malformations of genital organs
0.008 0.992 0.000
Q66 Congenital deformities of feet
0.008 0.992 0.000
Q65 Congenital deformities of hip
0.008 0.992 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.008 0.992 0.000
Q76 Congenital malformations of spine and bony thorax
0.008 0.992 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.008 0.992 0.000
H36 Retinal disorders in diseases classified elsewhere
0.000 0.992 0.008
Q25 Congenital malformations of great arteries
0.008 0.992 0.000
Q40 Other congenital malformations of upper alimentary tract
0.008 0.992 0.000
Q43.0 Meckel's diverticulum
0.008 0.992 0.000
Q45 Other congenital malformations of digestive system
0.008 0.992 0.000
Q44.6 Cystic disease of liver
0.007 0.992 0.000
Q61.3 Polycystic kidney, unspecified
0.007 0.992 0.000
Q51 Congenital malformations of uterus and cervix
0.007 0.993 0.000
Q51.2 Other doubling of uterus
0.007 0.993 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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