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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75893551
log Bayes Factor = 10.605
Chromosome 11   position 107,090,471  (GRCh37) Explore rs75893551 on Ensembl!
Variant rs75893551 is part of Cluster X0138

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I10 Essential (primary) hypertension
1.000 0.000 0.000
I10-I15 Hypertensive diseases
0.999 0.001 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
M05-M14 Inflammatory polyarthropathies
0.999 0.001 0.000
Chapter XXI Factors influencing health status and contact with health services
0.998 0.002 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.998 0.002 0.000
I20-I25 Ischaemic heart diseases
0.997 0.003 0.000
Z98 Other postsurgical states
0.995 0.005 0.000
Z85 Personal history of malignant neoplasm
0.995 0.005 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.995 0.005 0.000
J40-J47 Chronic lower respiratory diseases
0.995 0.005 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.995 0.005 0.000
Z87 Personal history of other diseases and conditions
0.994 0.006 0.000
Chapter VIII Diseases of the ear and mastoid process
0.993 0.007 0.000
Z98.8 Other specified postsurgical states
0.992 0.008 0.000
I21 Acute myocardial infarction
0.990 0.010 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.987 0.013 0.000
Chapter II Neoplasms
0.986 0.014 0.000
E70-E90 Metabolic disorders
0.984 0.016 0.000
H90-H95 Other disorders of ear
0.981 0.019 0.000
M20-M25 Other joint disorders
0.980 0.020 0.000
M23 Internal derangement of knee
0.976 0.024 0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue
0.976 0.024 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.975 0.025 0.000
Z87.4 Personal history of diseases of the genito-urinary system
0.973 0.027 0.000
M06 Other rheumatoid arthritis
0.973 0.027 0.000
J95-J99 Other diseases of the respiratory system
0.973 0.027 0.000
H91 Other hearing loss
0.971 0.029 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.971 0.029 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.970 0.030 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.967 0.033 0.000
I25 Chronic ischaemic heart disease
0.965 0.035 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.960 0.040 0.000
E78.0 Pure hypercholesterolaemia
0.960 0.040 0.000
M13 Other arthritis
0.959 0.041 0.000
H91.9 Hearing loss, unspecified
0.955 0.045 0.000
J98 Other respiratory disorders
0.950 0.050 0.000
E10-E14 Diabetes mellitus
0.947 0.053 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.945 0.055 0.000
H80-H83 Diseases of inner ear
0.944 0.056 0.000
M06.9 Rheumatoid arthritis, unspecified
0.941 0.059 0.000
J47 Bronchiectasis
0.937 0.063 0.000
I25.1 Atherosclerotic heart disease
0.936 0.064 0.000
I21.4 Acute subendocardial myocardial infarction
0.935 0.065 0.000
J98.1 Pulmonary collapse
0.934 0.066 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.930 0.070 0.000
M13.9 Arthritis, unspecified
0.928 0.072 0.000
E11 Non-insulin-dependent diabetes mellitus
0.928 0.072 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.921 0.079 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.920 0.080 0.000
H81 Disorders of vestibular function
0.918 0.082 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.916 0.084 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.916 0.084 0.000
J43 Emphysema
0.913 0.087 0.000
E11.9 Without complications
0.912 0.088 0.000
J40 Bronchitis, not specified as acute or chronic
0.906 0.094 0.000
D00-D09 In situ neoplasms
0.906 0.094 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.906 0.094 0.000
M80-M85 Disorders of bone density and structure
0.905 0.095 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.904 0.096 0.000
M65-M68 Disorders of synovium and tendon
0.901 0.099 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.901 0.099 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.899 0.101 0.000
M05 Seropositive rheumatoid arthritis
0.892 0.108 0.000
E87.7 Fluid overload
0.891 0.109 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.890 0.110 0.000
M07 Psoriatic and enteropathic arthropathies
0.885 0.115 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.878 0.122 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.870 0.130 0.000
M86-M90 Other osteopathies
0.868 0.132 0.000
Z94 Transplanted organ and tissue status
0.866 0.134 0.000
H81.0 Meniere's disease
0.862 0.138 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.859 0.141 0.000
C92 Myeloid leukaemia
0.856 0.144 0.000
J43.9 Emphysema, unspecified
0.855 0.145 0.000
J90-J94 Other diseases of pleura
0.855 0.145 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.854 0.146 0.000
H91.3 Deaf mutism, not elsewhere classified
0.854 0.146 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.849 0.151 0.000
Z98.0 Intestinal bypass and anastomosis status
0.847 0.153 0.000
S80-S89 Injuries to the knee and lower leg
0.846 0.154 0.000
C34 Malignant neoplasm of bronchus and lung
0.844 0.156 0.000
M65 Synovitis and tenosynovitis
0.841 0.159 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.841 0.159 0.000
J42 Unspecified chronic bronchitis
0.841 0.159 0.000
C71 Malignant neoplasm of brain
0.841 0.159 0.000
E87.2 Acidosis
0.838 0.162 0.000
J00-J06 Acute upper respiratory infections
0.836 0.164 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.834 0.166 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.833 0.167 0.000
M70-M79 Other soft tissue disorders
0.831 0.169 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.830 0.170 0.000
M50-M54 Other dorsopathies
0.826 0.174 0.000
C90.0 Multiple myeloma
0.823 0.177 0.000
C34.3 Lower lobe, bronchus or lung
0.822 0.178 0.000
D03 Melanoma in situ
0.821 0.179 0.000
M21 Other acquired deformities of limbs
0.821 0.179 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.821 0.179 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.820 0.180 0.000
M81 Osteoporosis without pathological fracture
0.820 0.180 0.000
Z87.1 Personal history of diseases of the digestive system
0.818 0.182 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.817 0.183 0.000
Chapter VI Diseases of the nervous system
0.816 0.184 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.816 0.184 0.000
M24 Other specific joint derangements
0.814 0.186 0.000
M23.8 Other internal derangements of knee
0.813 0.187 0.000
J98.4 Other disorders of lung
0.811 0.189 0.000
I20 Angina pectoris
0.810 0.190 0.000
S82 Fracture of lower leg, including ankle
0.809 0.191 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.806 0.194 0.000
M07.3 Other psoriatic arthropathies
0.803 0.197 0.000
E87.5 Hyperkalaemia
0.799 0.201 0.000
Z84 Family history of other conditions
0.797 0.203 0.000
J44 Other chronic obstructive pulmonary disease
0.797 0.203 0.000
C83.3 Large cell (diffuse)
0.797 0.203 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.796 0.204 0.000
E20-E35 Disorders of other endocrine glands
0.795 0.205 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.793 0.207 0.000
D03.3 Melanoma in situ of other and unspecified parts of face
0.792 0.208 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.790 0.210 0.000
M23.5 Chronic instability of knee
0.790 0.210 0.000
Z85.6 Personal history of leukaemia
0.789 0.211 0.000
Z94.8 Other transplanted organ and tissue status
0.788 0.212 0.000
E87.3 Alkalosis
0.783 0.217 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.783 0.217 0.000
M00-M03 Infectious arthropathies
0.783 0.217 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.781 0.219 0.000
J09-J18 Influenza and pneumonia
0.779 0.221 0.000
H93 Other disorders of ear, not elsewhere classified
0.778 0.222 0.000
H81.2 Vestibular neuronitis
0.777 0.223 0.000
M81.9 Osteoporosis, unspecified
0.776 0.224 0.000
M06.0 Seronegative rheumatoid arthritis
0.773 0.227 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.773 0.227 0.000
C81 Hodgkin's disease
0.772 0.228 0.000
M06.3 Rheumatoid nodule
0.771 0.228 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.771 0.229 0.000
I05-I09 Chronic rheumatic heart diseases
0.770 0.230 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.770 0.230 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.769 0.231 0.000
H90 Conductive and sensorineural hearing loss
0.768 0.232 0.000
H60-H62 Diseases of external ear
0.766 0.234 0.000
E11.4 With neurological complications
0.766 0.234 0.000
C64-C68 Malignant neoplasms of urinary tract
0.765 0.235 0.000
Chapter XXII Codes for special purposes
0.765 0.235 0.000
D04 Carcinoma in situ of skin
0.762 0.238 0.000
E11.8 With unspecified complications
0.761 0.238 0.000
E88 Other metabolic disorders
0.759 0.240 0.000
S90-S99 Injuries to the ankle and foot
0.759 0.241 0.000
I23 Certain current complications following acute myocardial infarction
0.759 0.241 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.756 0.244 0.000
E74 Other disorders of carbohydrate metabolism
0.756 0.244 0.000
G40-G47 Episodic and paroxysmal disorders
0.755 0.245 0.000
E78.8 Other disorders of lipoprotein metabolism
0.754 0.246 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.754 0.246 0.000
E73 Lactose intolerance
0.751 0.249 0.000
S82.5 Fracture of medial malleolus
0.750 0.250 0.000
M40-M43 Deforming dorsopathies
0.750 0.250 0.000
E11.0 With coma
0.749 0.251 0.000
E87.0 Hyperosmolality and hypernatraemia
0.748 0.252 0.000
M24.1 Other articular cartilage disorders
0.748 0.252 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.748 0.252 0.000
M60-M63 Disorders of muscles
0.746 0.254 0.000
C90.3 Solitary plasmacytoma
0.746 0.254 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.746 0.254 0.000
Z98.1 Arthrodesis status
0.745 0.255 0.000
E78.1 Pure hyperglyceridaemia
0.744 0.256 0.000
J46 Status asthmaticus
0.743 0.257 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.743 0.257 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.739 0.261 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.738 0.262 0.000
Z98.2 Presence of cerebrospinal fluid drainage device
0.738 0.262 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.738 0.262 0.000
M75 Shoulder lesions
0.737 0.263 0.000
S40-S49 Injuries to the shoulder and upper arm
0.737 0.263 0.000
M54 Dorsalgia
0.736 0.264 0.000
J93 Pneumothorax
0.735 0.265 0.000
E85 Amyloidosis
0.733 0.266 0.000
D09 Carcinoma in situ of other and unspecified sites
0.733 0.267 0.000
M35 Other systemic involvement of connective tissue
0.732 0.268 0.000
E40-E46 Malnutrition
0.731 0.269 0.000
E16 Other disorders of pancreatic internal secretion
0.730 0.270 0.000
S82.3 Fracture of lower end of tibia
0.728 0.272 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.728 0.272 0.000
Z81 Family history of mental and behavioural disorders
0.728 0.272 0.000
Q00-Q07 Congenital malformations of the nervous system
0.728 0.272 0.000
C91 Lymphoid leukaemia
0.727 0.273 0.000
H81.9 Disorder of vestibular function, unspecified
0.726 0.273 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.726 0.274 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.725 0.275 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.723 0.277 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.723 0.277 0.000
M21.2 Flexion deformity
0.721 0.278 0.000
M84 Disorders of continuity of bone
0.721 0.279 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.720 0.280 0.000
Z73 Problems related to life-management difficulty
0.720 0.280 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
J86 Pyothorax
0.717 0.283 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.717 0.283 0.000
I13 Hypertensive heart and renal disease
0.717 0.283 0.000
M14 Arthropathies in other diseases classified elsewhere
0.716 0.284 0.000
M12 Other specific arthropathies
0.716 0.284 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.716 0.284 0.000
M08 Juvenile arthritis
0.716 0.284 0.000
M85 Other disorders of bone density and structure
0.716 0.284 0.000
M13.0 Polyarthritis, unspecified
0.716 0.284 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.716 0.284 0.000
C92.1 Chronic myeloid leukaemia
0.715 0.285 0.000
M23.9 Internal derangement of knee, unspecified
0.715 0.285 0.000
C92.0 Acute myeloid leukaemia
0.714 0.286 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.714 0.286 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.714 0.286 0.000
J41 Simple and mucopurulent chronic bronchitis
0.713 0.287 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.713 0.287 0.000
Z87.6 Personal history of certain conditions arising in the perinatal period
0.712 0.287 0.000
M34 Systemic sclerosis
0.712 0.288 0.000
I15 Secondary hypertension
0.711 0.289 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.711 0.289 0.000
C71.9 Brain, unspecified
0.711 0.289 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.710 0.290 0.000
M87 Osteonecrosis
0.709 0.291 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.709 0.291 0.000
S50-S59 Injuries to the elbow and forearm
0.708 0.292 0.000
S82.50 Fracture of medial malleolus (closed)
0.708 0.292 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.706 0.294 0.000
E84 Cystic fibrosis
0.705 0.295 0.000
E79 Disorders of purine and pyrimidine metabolism
0.705 0.295 0.000
E77 Disorders of glycoprotein metabolism
0.705 0.295 0.000
E76 Disorders of glycosaminoglycan metabolism
0.705 0.295 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.705 0.295 0.000
E72 Other disorders of amino-acid metabolism
0.705 0.295 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.705 0.295 0.000
E70 Disorders of aromatic amino-acid metabolism
0.705 0.295 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.705 0.295 0.000
I11 Hypertensive heart disease
0.704 0.295 0.000
H81.1 Benign paroxysmal vertigo
0.704 0.296 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.704 0.296 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.703 0.297 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.703 0.297 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.702 0.298 0.000
M33 Dermatopolymyositis
0.702 0.298 0.000
M32 Systemic lupus erythematosus
0.702 0.298 0.000
M30 Polyarteritis nodosa and related conditions
0.702 0.298 0.000
Z87.0 Personal history of diseases of the respiratory system
0.702 0.298 0.000
J94 Other pleural conditions
0.701 0.299 0.000
M23.1 Discoid meniscus (congenital)
0.700 0.300 0.000
M23.0 Cystic meniscus
0.700 0.300 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.700 0.300 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.700 0.300 0.000
I25.3 Aneurysm of heart
0.699 0.301 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.699 0.301 0.000
M06.8 Other specified rheumatoid arthritis
0.697 0.303 0.000
M06.2 Rheumatoid bursitis
0.697 0.303 0.000
M06.1 Adult-onset Still's disease
0.697 0.303 0.000
J96 Respiratory failure, not elsewhere classified
0.697 0.303 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.697 0.303 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.697 0.303 0.000
H91.8 Other specified hearing loss
0.696 0.304 0.000
H91.2 Sudden idiopathic hearing loss
0.696 0.304 0.000
H91.1 Presbycusis
0.696 0.304 0.000
H91.0 Ototoxic hearing loss
0.696 0.304 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.696 0.304 0.000
C95 Leukaemia of unspecified cell type
0.696 0.304 0.000
C94 Other leukaemias of specified cell type
0.696 0.304 0.000
C93 Monocytic leukaemia
0.696 0.304 0.000
C88 Malignant immunoproliferative diseases
0.696 0.304 0.000
C86 Other specified types of T/NK-cell lymphoma
0.696 0.304 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.696 0.304 0.000
Q60-Q64 Congenital malformations of the urinary system
0.695 0.305 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.695 0.305 0.000
S86 Injury of muscle and tendon at lower leg level
0.694 0.305 0.000
E11.3 With ophthalmic complications
0.694 0.306 0.000
E78.6 Lipoprotein deficiency
0.694 0.306 0.000
E78.3 Hyperchylomicronaemia
0.694 0.306 0.000
I25.6 Silent myocardial ischaemia
0.692 0.308 0.000
I25.4 Coronary artery aneurysm
0.692 0.308 0.000
M11 Other crystal arthropathies
0.690 0.310 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.690 0.310 0.000
M54.3 Sciatica
0.689 0.311 0.000
E87.4 Mixed disorder of acid-base balance
0.688 0.312 0.000
M21.0 Valgus deformity, not elsewhere classified
0.688 0.312 0.000
M13.8 Other specified arthritis
0.688 0.312 0.000
M13.1 Monoarthritis, not elsewhere classified
0.688 0.312 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.688 0.312 0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium
0.686 0.314 0.000
D06 Carcinoma in situ of cervix uteri
0.686 0.314 0.000
J98.9 Respiratory disorder, unspecified
0.685 0.315 0.000
S60-S69 Injuries to the wrist and hand
0.685 0.315 0.000
G70-G73 Diseases of myoneural junction and muscle
0.685 0.315 0.000
M86 Osteomyelitis
0.684 0.316 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.682 0.318 0.000
J98.6 Disorders of diaphragm
0.681 0.319 0.000
J98.3 Compensatory emphysema
0.681 0.319 0.000
J98.2 Interstitial emphysema
0.681 0.319 0.000
C49.2 Connective and soft tissue of lower limb, including hip
0.681 0.319 0.000
M23.80 Other internal derangements of knee (Multiple sites)
0.681 0.319 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.680 0.320 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.679 0.320 0.000
E12 Malnutrition-related diabetes mellitus
0.679 0.321 0.000
E13 Other specified diabetes mellitus
0.677 0.323 0.000
H82 Vertiginous syndromes in diseases classified elsewhere
0.677 0.323 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.676 0.324 0.000
Z60 Problems related to social environment
0.675 0.325 0.000
C49.1 Connective and soft tissue of upper limb, including shoulder
0.675 0.325 0.000
C83.1 Small cleaved cell (diffuse)
0.675 0.325 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.674 0.326 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.674 0.326 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.674 0.326 0.000
C34.2 Middle lobe, bronchus or lung
0.674 0.326 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.673 0.327 0.000
I20.8 Other forms of angina pectoris
0.671 0.329 0.000
C90.2 Plasmacytoma, extramedullary
0.671 0.329 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.671 0.329 0.000
M06.4 Inflammatory polyarthropathy
0.670 0.330 0.000
E28 Ovarian dysfunction
0.669 0.331 0.000
T39.1 4-Aminophenol derivatives
0.667 0.333 0.000
M75.1 Rotator cuff syndrome
0.667 0.333 0.000
C49.9 Connective and soft tissue, unspecified
0.666 0.334 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.665 0.335 0.000
E11.7 With multiple complications
0.665 0.335 0.000
E11.6 With other specified complications
0.665 0.335 0.000
S81 Open wound of lower leg
0.663 0.337 0.000
Z94.4 Liver transplant status
0.660 0.340 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.660 0.340 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.660 0.340 0.000
T33-T35 Frostbite
0.660 0.340 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.660 0.340 0.000
T00-T07 Injuries involving multiple body regions
0.660 0.340 0.000
Q80-Q89 Other congenital malformations
0.659 0.341 0.000
M89 Other disorders of bone
0.659 0.341 0.000
J04 Acute laryngitis and tracheitis
0.659 0.341 0.000
H81.8 Other disorders of vestibular function
0.658 0.342 0.000
H81.4 Vertigo of central origin
0.658 0.342 0.000
H81.3 Other peripheral vertigo
0.658 0.342 0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.657 0.343 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.657 0.343 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.657 0.343 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.657 0.343 0.000
Z82.2 Family history of deafness and hearing loss
0.657 0.343 0.000
Z82.1 Family history of blindness and visual loss
0.657 0.343 0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.657 0.343 0.000
I08 Multiple valve diseases
0.656 0.344 0.000
C71.2 Temporal lobe
0.656 0.344 0.000
Z71.3 Dietary counselling and surveillance
0.656 0.344 0.000
C67 Malignant neoplasm of bladder
0.655 0.345 0.000
J43.8 Other emphysema
0.655 0.345 0.000
J43.2 Centrilobular emphysema
0.655 0.345 0.000
J43.1 Panlobular emphysema
0.655 0.345 0.000
J43.0 MacLeod's syndrome
0.655 0.345 0.000
M65.1 Other infective (teno)synovitis
0.655 0.345 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.654 0.346 0.000
Z56 Problems related to employment and unemployment
0.654 0.346 0.000
C71.1 Frontal lobe
0.654 0.346 0.000
M75.5 Bursitis of shoulder
0.654 0.346 0.000
D04.4 Skin of scalp and neck
0.654 0.346 0.000
Z84.8 Family history of other specified conditions
0.653 0.347 0.000
C71.0 Cerebrum, except lobes and ventricles
0.652 0.348 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.652 0.348 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.652 0.348 0.000
E16.2 Hypoglycaemia, unspecified
0.651 0.349 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.650 0.350 0.000
M54.39 Sciatica (Site unspecified)
0.650 0.350 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.649 0.351 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.649 0.351 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.649 0.351 0.000
C90.1 Plasma cell leukaemia
0.649 0.351 0.000
M83 Adult osteomalacia
0.649 0.351 0.000
M82 Osteoporosis in diseases classified elsewhere
0.649 0.351 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.648 0.352 0.000
Q35-Q37 Cleft lip and cleft palate
0.648 0.352 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.648 0.352 0.000
J02 Acute pharyngitis
0.648 0.352 0.000
H83 Other diseases of inner ear
0.647 0.353 0.000
I12 Hypertensive renal disease
0.647 0.353 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.647 0.353 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.646 0.354 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.646 0.354 0.000
C70 Malignant neoplasm of meninges
0.646 0.354 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.644 0.356 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.644 0.356 0.000
C31 Malignant neoplasm of accessory sinuses
0.644 0.356 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.644 0.356 0.000
C37 Malignant neoplasm of thymus
0.644 0.356 0.000
C33 Malignant neoplasm of trachea
0.644 0.356 0.000
I95 Hypotension
0.644 0.356 0.000
M50 Cervical disk disorders
0.644 0.356 0.000
C71.3 Parietal lobe
0.643 0.356 0.000
C71.8 Overlapping lesion of brain
0.643 0.356 0.000
E10 Insulin-dependent diabetes mellitus
0.643 0.357 0.000
M23.4 Loose body in knee
0.642 0.357 0.000
M90 Osteopathies in diseases classified elsewhere
0.642 0.358 0.000
S61 Open wound of wrist and hand
0.641 0.359 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.640 0.359 0.000
C69 Malignant neoplasm of eye and adnexa
0.640 0.360 0.000
M05.8 Other seropositive rheumatoid arthritis
0.639 0.360 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.639 0.360 0.000
M05.2 Rheumatoid vasculitis
0.639 0.360 0.000
M05.1 Rheumatoid lung disease
0.639 0.360 0.000
M05.0 Felty's syndrome
0.639 0.360 0.000
S10-S19 Injuries to the neck
0.639 0.361 0.000
T92 Sequelae of injuries of upper limb
0.639 0.361 0.000
M54.1 Radiculopathy
0.638 0.362 0.000
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites
0.638 0.362 0.000
M91-M94 Chondropathies
0.638 0.362 0.000
J93.9 Pneumothorax, unspecified
0.638 0.362 0.000
S82.31 Fracture of lower end of tibia (open)
0.637 0.363 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.637 0.363 0.000
I99 Other and unspecified disorders of circulatory system
0.637 0.363 0.000
M13.98 Arthritis, unspecified (Other)
0.636 0.364 0.000
S40 Superficial injury of shoulder and upper arm
0.636 0.364 0.000
E78.4 Other hyperlipidaemia
0.636 0.364 0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.636 0.364 0.000
M65.3 Trigger finger
0.635 0.365 0.000
M07.6 Other enteropathic arthropathies
0.634 0.366 0.000
M07.5 Arthropathy in ulcerative colitis
0.634 0.366 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.634 0.366 0.000
M07.2 Psoriatic spondylitis
0.634 0.366 0.000
M07.1 Arthritis mutilans
0.634 0.366 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.634 0.366 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.634 0.366 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.634 0.366 0.000
G61 Inflammatory polyneuropathy
0.633 0.367 0.000
H93.1 Tinnitus
0.633 0.367 0.000
Z73.3 Stress, not elsewhere classified
0.633 0.367 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.633 0.367 0.000
M66 Spontaneous rupture of synovium and tendon
0.633 0.367 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.632 0.367 0.000
T91 Sequelae of injuries of neck and trunk
0.632 0.368 0.000
T79-T79 Certain early complications of trauma
0.631 0.368 0.000
C83.7 Burkitt's tumour
0.630 0.370 0.000
C83.6 Undifferentiated (diffuse)
0.630 0.370 0.000
C83.5 Lymphoblastic (diffuse)
0.630 0.370 0.000
C83.4 Immunoblastic (diffuse)
0.630 0.370 0.000
C83.2 Mixed small and large cell (diffuse)
0.630 0.370 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.630 0.370 0.000
C81.9 Hodgkin's disease, unspecified
0.630 0.370 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.629 0.371 0.000
Z75 Problems related to medical facilities and other health care
0.627 0.373 0.000
M06.34 Rheumatoid nodule (Hand)
0.627 0.373 0.000
Q18 Other congenital malformations of face and neck
0.627 0.373 0.000
M65.8 Other synovitis and tenosynovitis
0.627 0.373 0.000
Z97 Presence of other devices
0.627 0.373 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.626 0.374 0.000
J06.9 Acute upper respiratory infection, unspecified
0.626 0.374 0.000
M53 Other dorsopathies, not elsewhere classified
0.626 0.374 0.000
S82.0 Fracture of patella
0.626 0.374 0.000
M81.98 Osteoporosis, unspecified (Other)
0.625 0.375 0.000
J86.9 Pyothorax without fistula
0.625 0.375 0.000
J90 Pleural effusion, not elsewhere classified
0.624 0.376 0.000
M75.3 Calcific tendinitis of shoulder
0.624 0.376 0.000
Q76 Congenital malformations of spine and bony thorax
0.624 0.376 0.000
C49.0 Connective and soft tissue of head, face and neck
0.623 0.377 0.000
H80 Otosclerosis
0.623 0.377 0.000
J14 Pneumonia due to Haemophilus influenzae
0.623 0.377 0.000
Z63 Other problems related to primary support group, including family circumstances
0.623 0.377 0.000
M31 Other necrotising vasculopathies
0.622 0.378 0.000
J60-J70 Lung diseases due to external agents
0.622 0.378 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.622 0.378 0.000
M88 Paget's disease of bone [osteitis deformans]
0.621 0.378 0.000
I08.0 Disorders of both mitral and aortic valves
0.622 0.378 0.000
Q66 Congenital deformities of feet
0.621 0.379 0.000
Z94.9 Transplanted organ and tissue status, unspecified
0.621 0.379 0.000
Z94.6 Bone transplant status
0.621 0.379 0.000
Z94.5 Skin transplant status
0.621 0.379 0.000
Z94.3 Heart and lungs transplant status
0.621 0.379 0.000
Z94.2 Lung transplant status
0.621 0.379 0.000
Z94.1 Heart transplant status
0.621 0.379 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.620 0.380 0.000
D04.3 Skin of other and unspecified parts of face
0.620 0.380 0.000
T66-T78 Other and unspecified effects of external causes
0.620 0.380 0.000
T18 Foreign body in alimentary tract
0.619 0.381 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.617 0.383 0.000
C73 Malignant neoplasm of thyroid gland
0.617 0.383 0.000
S82.2 Fracture of shaft of tibia
0.617 0.383 0.000
I20.9 Angina pectoris, unspecified
0.617 0.383 0.000
E65-E68 Obesity and other hyperalimentation
0.616 0.384 0.000
S50 Superficial injury of forearm
0.616 0.384 0.000
M67 Other disorders of synovium and tendon
0.615 0.384 0.000
E87.6 Hypokalaemia
0.615 0.384 0.000
H60 Otitis externa
0.615 0.385 0.000
I20.1 Angina pectoris with documented spasm
0.615 0.385 0.000
D03.4 Melanoma in situ of scalp and neck
0.614 0.386 0.000
C92.9 Myeloid leukaemia, unspecified
0.614 0.386 0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.614 0.386 0.000
C92.7 Other myeloid leukaemia
0.614 0.386 0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.614 0.386 0.000
C92.5 Acute myelomonocytic leukaemia
0.614 0.386 0.000
C92.4 Acute promyelocytic leukaemia
0.614 0.386 0.000
C92.3 Myeloid sarcoma
0.614 0.386 0.000
C92.2 Subacute myeloid leukaemia
0.614 0.386 0.000
M21.24 Flexion deformity (Hand)
0.613 0.386 0.000
S99 Other and unspecified injuries of ankle and foot
0.613 0.387 0.000
E27 Other disorders of adrenal gland
0.613 0.387 0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.613 0.387 0.000
C46 Kaposi's sarcoma
0.613 0.387 0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.612 0.388 0.000
M87.2 Osteonecrosis due to previous trauma
0.612 0.388 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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