TreeWAS – Variant ID: rs7628219

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E87.7 Fluid overload	0.244	0.756	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.194	0.806	0.000
E87.3 Alkalosis	0.182	0.818	0.000
E87.5 Hyperkalaemia	0.181	0.819	0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.157	0.843	0.000
E87.2 Acidosis	0.153	0.847	0.000
E87.4 Mixed disorder of acid-base balance	0.139	0.861	0.000
E87.0 Hyperosmolality and hypernatraemia	0.135	0.864	0.000
N20.1 Calculus of ureter	0.129	0.871	0.000
N20 Calculus of kidney and ureter	0.119	0.881	0.000
N20.2 Calculus of kidney with calculus of ureter	0.111	0.889	0.000
N20.0 Calculus of kidney	0.110	0.890	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.105	0.895	0.000
T42.4 Benzodiazepines	0.104	0.896	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.100	0.900	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.093	0.907	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.090	0.909	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.090	0.910	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.087	0.913	0.000
T42.1 Iminostilbenes	0.086	0.914	0.000
T42.0 Hydantoin derivatives	0.081	0.919	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.079	0.921	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.079	0.921	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.078	0.922	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.075	0.924	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.075	0.924	0.000
T42.3 Barbiturates	0.075	0.924	0.000
T42.2 Succinimides and oxazolidinediones	0.075	0.924	0.000
E87.6 Hypokalaemia	0.075	0.925	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.074	0.926	0.000
N20.9 Urinary calculus, unspecified	0.074	0.926	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.072	0.928	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.067	0.933	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.067	0.933	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.067	0.933	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.067	0.933	0.000
T50.4 Drugs affecting uric acid metabolism	0.066	0.933	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.066	0.933	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.065	0.935	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.065	0.935	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.065	0.935	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.065	0.935	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.065	0.935	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.065	0.935	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.065	0.935	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.065	0.935	0.000
T44.0 Anticholinesterase agents	0.065	0.935	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.065	0.935	0.000
T36 Poisoning by systemic antibiotics	0.064	0.935	0.000
T50.8 Diagnostic agents	0.063	0.937	0.000
T50.7 Analeptics and opioid receptor antagonists	0.063	0.937	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.063	0.937	0.000
T50.5 Appetite depressants	0.063	0.937	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.063	0.937	0.000
T50.1 Loop [high-ceiling] diuretics	0.063	0.937	0.000
T50.0 Mineralocorticoids and their antagonists	0.063	0.937	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.062	0.938	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.062	0.938	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.060	0.940	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.059	0.941	0.000
D86.9 Sarcoidosis, unspecified	0.057	0.943	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.057	0.943	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.057	0.943	0.000
T46.7 Peripheral vasodilators	0.057	0.943	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.057	0.943	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.057	0.943	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.057	0.943	0.000
T46.1 Calcium-channel blockers	0.056	0.943	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.056	0.943	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.056	0.944	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.055	0.945	0.000
D86 Sarcoidosis	0.054	0.946	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.053	0.947	0.000
T47.0 Histamine H(2)-receptor antagonists	0.052	0.948	0.000
T38.9 Other and unspecified hormone antagonists	0.052	0.948	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.052	0.948	0.000
T38.7 Androgens and anabolic congeners	0.052	0.948	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.052	0.948	0.000
T38.5 Other oestrogens and progestogens	0.052	0.948	0.000
T38.4 Oral contraceptives	0.052	0.948	0.000
T38.2 Antithyroid drugs	0.052	0.948	0.000
T38.1 Thyroid hormones and substitutes	0.052	0.948	0.000
T38.0 Glucocorticoids and synthetic analogues	0.052	0.948	0.000
D86.8 Sarcoidosis of other and combined sites	0.050	0.950	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.049	0.951	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.048	0.952	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.048	0.952	0.000
T37.5 Antiviral drugs	0.048	0.952	0.000
T37.4 Anthelminthics	0.048	0.952	0.000
T37.3 Other antiprotozoal drugs	0.048	0.952	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.048	0.952	0.000
T37.1 Antimycobacterial drugs	0.048	0.952	0.000
T37.0 Sulphonamides	0.048	0.952	0.000
T41.5 Therapeutic gases	0.048	0.952	0.000
T41.4 Anaesthetic, unspecified	0.048	0.952	0.000
T41.3 Local anaesthetics	0.048	0.952	0.000
T41.2 Other and unspecified general anaesthetics	0.048	0.952	0.000
T41.1 Intravenous anaesthetics	0.048	0.952	0.000
T41.0 Inhaled anaesthetics	0.048	0.952	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.048	0.952	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.048	0.952	0.000
T48.5 Anti-common-cold drugs	0.048	0.952	0.000
T48.4 Expectorants	0.048	0.952	0.000
T48.3 Antitussives	0.048	0.952	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.048	0.952	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.048	0.952	0.000
T48.0 Oxytocic drugs	0.048	0.952	0.000
T49.9 Topical agent, unspecified	0.048	0.952	0.000
T49.8 Other topical agents	0.048	0.952	0.000
T49.7 Dental drugs, topically applied	0.048	0.952	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.048	0.952	0.000
T49.5 Ophthalmological drugs and preparations	0.048	0.952	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.048	0.952	0.000
T49.3 Emollients, demulcents and protectants	0.048	0.952	0.000
T49.2 Local astringents and local detergents	0.048	0.952	0.000
T49.1 Antipruritics	0.048	0.952	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.048	0.952	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.048	0.952	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.048	0.952	0.000
T47.7 Emetics	0.048	0.952	0.000
T47.6 Antidiarrhoeal drugs	0.048	0.952	0.000
T47.5 Digestants	0.048	0.952	0.000
T47.4 Other laxatives	0.048	0.952	0.000
T47.3 Saline and osmotic laxatives	0.048	0.952	0.000
T47.2 Stimulant laxatives	0.048	0.952	0.000
T40.6 Other and unspecified narcotics	0.047	0.952	0.000
T43.9 Psychotropic drug, unspecified	0.047	0.953	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.047	0.953	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.047	0.953	0.000
T36.9 Systemic antibiotic, unspecified	0.046	0.953	0.000
T36.8 Other systemic antibiotics	0.046	0.953	0.000
T36.7 Antifungal antibiotics, systemically used	0.046	0.953	0.000
T36.6 Rifamycins	0.046	0.953	0.000
T36.5 Aminoglycosides	0.046	0.953	0.000
T36.4 Tetracyclines	0.046	0.953	0.000
T36.3 Macrolides	0.046	0.953	0.000
T36.2 Chloramphenicol group	0.046	0.953	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.046	0.953	0.000
T36.0 Penicillins	0.044	0.956	0.000
D86.1 Sarcoidosis of lymph nodes	0.044	0.956	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.043	0.956	0.000
T40.8 Lysergide [LSD]	0.043	0.956	0.000
T40.7 Cannabis (derivatives)	0.043	0.956	0.000
T40.5 Cocaine	0.043	0.956	0.000
T40.3 Methadone	0.043	0.956	0.000
T40.1 Heroin	0.043	0.956	0.000
T40.0 Opium	0.043	0.956	0.000
D86.0 Sarcoidosis of lung	0.044	0.956	0.000
T43.6 Psychostimulants with abuse potential	0.043	0.957	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.042	0.958	0.000
T45.2 Vitamins, not elsewhere classified	0.040	0.959	0.000
T40.2 Other opioids	0.040	0.960	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.039	0.961	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.038	0.962	0.000
T45.8 Other primarily systemic and haematological agents	0.038	0.962	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.038	0.962	0.000
T45.6 Fibrinolysis-affecting drugs	0.038	0.962	0.000
T45.4 Iron and its compounds	0.038	0.962	0.000
T45.3 Enzymes, not elsewhere classified	0.038	0.962	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.038	0.962	0.000
T45.5 Anticoagulants	0.038	0.962	0.000
D86.3 Sarcoidosis of skin	0.037	0.963	0.000
D80-D89 Certain disorders involving the immune mechanism	0.036	0.964	0.000
T40.4 Other synthetic narcotics	0.036	0.964	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.034	0.966	0.000
N20-N23 Urolithiasis	0.034	0.966	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.031	0.969	0.000
T45.0 Antiallergic and antiemetic drugs	0.028	0.971	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.028	0.972	0.000
D84 Other immunodeficiencies	0.028	0.972	0.000
D80 Immunodeficiency with predominantly antibody defects	0.028	0.972	0.000
D83 Common variable immunodeficiency	0.026	0.974	0.000
D82 Immunodeficiency associated with other major defects	0.026	0.974	0.000
D81 Combined immunodeficiencies	0.026	0.974	0.000
N21 Calculus of lower urinary tract	0.025	0.974	0.000
N22 Calculus of urinary tract in diseases classified elsewhere	0.024	0.976	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.023	0.977	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.023	0.977	0.000
D89.3 Immune reconstitution syndrome	0.023	0.977	0.000
D89.1 Cryoglobulinaemia	0.023	0.977	0.000
O80.0 Spontaneous vertex delivery	0.023	0.977	0.000
D84.9 Immunodeficiency, unspecified	0.022	0.977	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.022	0.978	0.000
E70-E90 Metabolic disorders	0.022	0.978	0.000
Z09.8 Follow-up examination after other treatment for other conditions	0.022	0.978	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.021	0.978	0.000
R26.8 Other and unspecified abnormalities of gait and mobility	0.022	0.978	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.021	0.979	0.000
N21.1 Calculus in urethra	0.021	0.979	0.000
J81 Pulmonary oedema	0.021	0.979	0.000
D84.8 Other specified immunodeficiencies	0.020	0.979	0.000
D84.1 Defects in the complement system	0.020	0.979	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.020	0.979	0.000
E88 Other metabolic disorders	0.021	0.979	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.020	0.980	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.020	0.980	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.020	0.980	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.020	0.980	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.020	0.980	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.020	0.980	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.020	0.980	0.000
D81.9 Combined immunodeficiency, unspecified	0.019	0.981	0.000
D81.8 Other combined immunodeficiencies	0.019	0.981	0.000
D81.7 Major histocompatibility complex class II deficiency	0.019	0.981	0.000
D81.6 Major histocompatibility complex class I deficiency	0.019	0.981	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.019	0.981	0.000
D81.4 Nezelof's syndrome	0.019	0.981	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.019	0.981	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.019	0.981	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.019	0.981	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.019	0.981	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.019	0.981	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.019	0.981	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.019	0.981	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.019	0.981	0.000
D82.2 Immunodeficiency with short-limbed stature	0.019	0.981	0.000
D82.1 Di George's syndrome	0.019	0.981	0.000
D82.0 Wiskott-Aldrich syndrome	0.019	0.981	0.000
D83.9 Common variable immunodeficiency, unspecified	0.019	0.981	0.000
D83.8 Other common variable immunodeficiencies	0.019	0.981	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.019	0.981	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.019	0.981	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.019	0.981	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.019	0.981	0.000
N21.8 Other lower urinary tract calculus	0.019	0.981	0.000
N21.9 Calculus of lower urinary tract, unspecified	0.018	0.981	0.000
T43.2 Other and unspecified antidepressants	0.018	0.981	0.000
E87.1 Hypo-osmolality and hyponatraemia	0.018	0.982	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.018	0.982	0.000
N22.8 Calculus of urinary tract in other diseases classified elsewhere	0.018	0.982	0.000
N22.0 Calculus of urinary tract in schistosomiasis [bilharziasis]	0.018	0.982	0.000
E74 Other disorders of carbohydrate metabolism	0.018	0.982	0.000
E73 Lactose intolerance	0.018	0.982	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.017	0.983	0.000
E85 Amyloidosis	0.017	0.983	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.017	0.983	0.000
E88.3 Tumour lysis syndrome	0.016	0.984	0.000
E84 Cystic fibrosis	0.016	0.984	0.000
E79 Disorders of purine and pyrimidine metabolism	0.016	0.984	0.000
E77 Disorders of glycoprotein metabolism	0.016	0.984	0.000
E76 Disorders of glycosaminoglycan metabolism	0.016	0.984	0.000
E72 Other disorders of amino-acid metabolism	0.016	0.984	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.016	0.984	0.000
E70 Disorders of aromatic amino-acid metabolism	0.016	0.984	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.016	0.984	0.000
N21.0 Calculus in bladder	0.016	0.984	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.015	0.985	0.000
E88.9 Metabolic disorder, unspecified	0.015	0.985	0.000
E88.8 Other specified metabolic disorders	0.015	0.985	0.000
E85.8 Other amyloidosis	0.015	0.985	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.015	0.985	0.000
C77.2 Intra-abdominal lymph nodes	0.000	0.985	0.015
E73.9 Lactose intolerance, unspecified	0.015	0.985	0.000
E75.5 Other lipid storage disorders	0.014	0.986	0.000
N23 Unspecified renal colic	0.014	0.986	0.000
E85.3 Secondary systemic amyloidosis	0.013	0.987	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.013	0.987	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.013	0.987	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.013	0.987	0.000
E74.2 Disorders of galactose metabolism	0.013	0.987	0.000
E74.1 Disorders of fructose metabolism	0.013	0.987	0.000
E74.0 Glycogen storage disease	0.013	0.987	0.000
E73.8 Other lactose intolerance	0.013	0.987	0.000
E73.1 Secondary lactase deficiency	0.013	0.987	0.000
E73.0 Congenital lactase deficiency	0.013	0.987	0.000
E80.1 Porphyria cutanea tarda	0.013	0.987	0.000
E75.6 Lipid storage disorder, unspecified	0.013	0.987	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.013	0.987	0.000
E75.3 Sphingolipidosis, unspecified	0.013	0.987	0.000
E75.2 Other sphingolipidosis	0.013	0.987	0.000
E75.1 Other gangliosidosis	0.013	0.987	0.000
E75.0 GM2 gangliosidosis	0.013	0.987	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.013	0.987	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.013	0.987	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.013	0.987	0.000
E88.2 Lipomatosis, not elsewhere classified	0.012	0.987	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.012	0.987	0.000
E80.6 Other disorders of bilirubin metabolism	0.012	0.988	0.000
E85.4 Organ-limited amyloidosis	0.012	0.988	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.012	0.988	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.012	0.988	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.012	0.988	0.000
E70.3 Albinism	0.012	0.988	0.000
E70.2 Disorders of tyrosine metabolism	0.012	0.988	0.000
E70.1 Other hyperphenylalaninaemias	0.012	0.988	0.000
E70.0 Classical phenylketonuria	0.012	0.988	0.000
E71.3 Disorders of fatty-acid metabolism	0.012	0.988	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.012	0.988	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.012	0.988	0.000
E71.0 Maple-syrup-urine disease	0.012	0.988	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.012	0.988	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.012	0.988	0.000
E72.5 Disorders of glycine metabolism	0.012	0.988	0.000
E72.4 Disorders of ornithine metabolism	0.012	0.988	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.012	0.988	0.000
E72.2 Disorders of urea cycle metabolism	0.012	0.988	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.012	0.988	0.000
E72.0 Disorders of amino-acid transport	0.012	0.988	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.012	0.988	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.012	0.988	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.012	0.988	0.000
E76.2 Other mucopolysaccharidoses	0.012	0.988	0.000
E76.1 Mucopolysaccharidosis, type II	0.012	0.988	0.000
E76.0 Mucopolysaccharidosis, type I	0.012	0.988	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.012	0.988	0.000
E77.8 Other disorders of glycoprotein metabolism	0.012	0.988	0.000
E77.1 Defects in glycoprotein degradation	0.012	0.988	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.012	0.988	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.012	0.988	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.012	0.988	0.000
E79.1 Lesch-Nyhan syndrome	0.012	0.988	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.012	0.988	0.000
E84.9 Cystic fibrosis, unspecified	0.012	0.988	0.000
E84.8 Cystic fibrosis with other manifestations	0.012	0.988	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.012	0.988	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.012	0.988	0.000
E85.9 Amyloidosis, unspecified	0.011	0.989	0.000
E89.3 Postprocedural hypopituitarism	0.011	0.989	0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.000	0.989	0.011
E80.7 Disorder of bilirubin metabolism, unspecified	0.011	0.989	0.000
E80.5 Crigler-Najjar syndrome	0.011	0.989	0.000
E80.3 Defects of catalase and peroxydase	0.011	0.989	0.000
E80.2 Other porphyria	0.011	0.989	0.000
E80.0 Hereditary erythropoietic porphyria	0.011	0.989	0.000
Q61.2 Polycystic kidney, adult type	0.011	0.989	0.000
C77.8 Lymph nodes of multiple regions	0.000	0.990	0.010
L30.9 Dermatitis, unspecified	0.010	0.990	0.000
S61.0 Open wound of finger(s) without damage to nail	0.010	0.990	0.000
C83.3 Large cell (diffuse)	0.000	0.990	0.010
C77.5 Intrapelvic lymph nodes	0.000	0.990	0.010
C77.4 Inguinal and lower limb lymph nodes	0.000	0.990	0.009
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.000	0.991	0.009
C77.9 Lymph node, unspecified	0.000	0.991	0.009
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.009	0.991	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.009	0.991	0.000
E89.5 Postprocedural testicular hypofunction	0.009	0.991	0.000
E89.4 Postprocedural ovarian failure	0.009	0.991	0.000
E89.1 Postprocedural hypoinsulinaemia	0.009	0.991	0.000
Q61 Cystic kidney disease	0.009	0.991	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.009	0.991	0.000
T39.4 Antirheumatics, not elsewhere classified	0.009	0.991	0.000
T39.2 Pyrazolone derivatives	0.009	0.991	0.000
O80 Single spontaneous delivery	0.008	0.992	0.000
T39.0 Salicylates	0.008	0.992	0.000
Q61.3 Polycystic kidney, unspecified	0.008	0.992	0.000
C77.1 Intrathoracic lymph nodes	0.000	0.992	0.008
D12.2 Ascending colon	0.008	0.992	0.000
E89.2 Postprocedural hypoparathyroidism	0.008	0.992	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.008	0.992	0.000
Q61.9 Cystic kidney disease, unspecified	0.008	0.992	0.000
J39.2 Other diseases of pharynx	0.008	0.992	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.000	0.993	0.007
N18.4 Chronic kidney disease, stage 4	0.007	0.993	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.000	0.993	0.007
Q61.8 Other cystic kidney diseases	0.007	0.993	0.000
Q61.4 Renal dysplasia	0.007	0.993	0.000
Q61.1 Polycystic kidney, infantile type	0.007	0.993	0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.000	0.993	0.007
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.000	0.993	0.007
Q61.5 Medullary cystic kidney	0.006	0.993	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.006	0.993	0.000
G93.0 Cerebral cysts	0.007	0.993	0.000
Q61.0 Congenital single renal cyst	0.006	0.994	0.000
R26 Abnormalities of gait and mobility	0.006	0.994	0.000
O80.1 Spontaneous breech delivery	0.006	0.994	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.000	0.994	0.006
I84.5 External haemorrhoids without complication	0.006	0.994	0.000
S61 Open wound of wrist and hand	0.006	0.994	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.000	0.994	0.006
C78.4 Secondary malignant neoplasm of small intestine	0.000	0.994	0.006
C78.1 Secondary malignant neoplasm of mediastinum	0.000	0.994	0.006
G99.2 Myelopathy in diseases classified elsewhere	0.000	0.994	0.006
N18.0 End-stage renal disease	0.006	0.994	0.000
R26.2 Difficulty in walking, not elsewhere classified	0.006	0.994	0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.000	0.994	0.006
N18 Chronic renal failure	0.006	0.994	0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.000	0.994	0.006
O80.8 Other single spontaneous delivery	0.005	0.994	0.000
G45.9 Transient cerebral ischaemic attack, unspecified	0.006	0.994	0.000
C78.2 Secondary malignant neoplasm of pleura	0.000	0.994	0.006
S61.1 Open wound of finger(s) with damage to nail	0.006	0.994	0.000
C83.7 Burkitt's tumour	0.000	0.995	0.005
C83.6 Undifferentiated (diffuse)	0.000	0.995	0.005
C83.5 Lymphoblastic (diffuse)	0.000	0.995	0.005
C83.4 Immunoblastic (diffuse)	0.000	0.995	0.005
C83.2 Mixed small and large cell (diffuse)	0.000	0.995	0.005
C83.1 Small cleaved cell (diffuse)	0.000	0.995	0.005
C77.0 Lymph nodes of head, face and neck	0.000	0.995	0.005
E83 Disorders of mineral metabolism	0.005	0.995	0.000
N18.5 Chronic kidney disease, stage 5	0.005	0.995	0.000
S61.7 Multiple open wounds of wrist and hand	0.005	0.995	0.000
N18.1 Chronic kidney disease, stage 1	0.005	0.995	0.000
R26.1 Paralytic gait	0.005	0.995	0.000
O80.9 Single spontaneous delivery, unspecified	0.005	0.995	0.000
L30 Other dermatitis	0.005	0.995	0.000
Q60-Q64 Congenital malformations of the urinary system	0.005	0.995	0.000
J03.9 Acute tonsillitis, unspecified	0.000	0.995	0.005
C83.0 Small cell (diffuse)	0.000	0.995	0.004
N18.9 Chronic renal failure, unspecified	0.005	0.995	0.000
C78.0 Secondary malignant neoplasm of lung	0.000	0.996	0.004
H52.1 Myopia	0.004	0.996	0.000
S64.4 Injury of digital nerve of other finger	0.004	0.996	0.000
E83.4 Disorders of magnesium metabolism	0.004	0.996	0.000
E80.4 Gilbert's syndrome	0.004	0.996	0.000
X41.9 Unspecified place	0.004	0.996	0.000
J39 Other diseases of upper respiratory tract	0.004	0.996	0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs	0.000	0.996	0.004
U88 Agent resistant to multiple antibiotics	0.000	0.996	0.004
R26.0 Ataxic gait	0.004	0.996	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.004	0.996	0.000
E83.8 Other disorders of mineral metabolism	0.004	0.996	0.000
E83.2 Disorders of zinc metabolism	0.004	0.996	0.000
E83.0 Disorders of copper metabolism	0.004	0.996	0.000
S60-S69 Injuries to the wrist and hand	0.004	0.996	0.000
Q64 Other congenital malformations of urinary system	0.004	0.996	0.000
S65 Injury of blood vessels at wrist and hand level	0.004	0.996	0.000
S60.8 Other superficial injuries of wrist and hand	0.004	0.996	0.000
J39.8 Other specified diseases of upper respiratory tract	0.004	0.996	0.000
C80 Malignant neoplasm without specification of site	0.000	0.996	0.004
C76 Malignant neoplasm of other and ill-defined sites	0.000	0.996	0.004
S64 Injury of nerves at wrist and hand level	0.004	0.996	0.000
S60 Superficial injury of wrist and hand	0.004	0.996	0.000
L30.4 Erythema intertrigo	0.004	0.996	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.004	0.996	0.000
Q63 Other congenital malformations of kidney	0.004	0.996	0.000
L30.5 Pityriasis alba	0.004	0.996	0.000
L30.3 Infective dermatitis	0.004	0.996	0.000
L30.2 Cutaneous autosensitisation	0.004	0.996	0.000
L30.1 Dyshidrosis [pompholyx]	0.004	0.996	0.000
L30.0 Nummular dermatitis	0.004	0.996	0.000
L30.8 Other specified dermatitis	0.004	0.996	0.000
S65.5 Injury of blood vessel(s) of other finger	0.004	0.996	0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.004	0.996	0.000
Q21.0 Ventricular septal defect	0.004	0.996	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.003	0.996	0.000
U89.8 Agent resistant to other single specified antibiotic	0.000	0.996	0.003
S62 Fracture at wrist and hand level	0.004	0.996	0.000
S61.9 Open wound of wrist and hand, part unspecified	0.003	0.996	0.000
N39.4 Other specified urinary incontinence	0.003	0.997	0.000
N18.3 Chronic kidney disease, stage 3	0.003	0.997	0.000
S61.8 Open wound of other parts of wrist and hand	0.003	0.997	0.000
G45.3 Amaurosis fugax	0.003	0.997	0.000
S65.1 Injury of radial artery at wrist and hand level	0.003	0.997	0.000
O80-O84 Delivery	0.003	0.997	0.000
S62.3 Fracture of other metacarpal bone	0.003	0.997	0.000
G45 Transient cerebral ischaemic attacks and related syndromes	0.003	0.997	0.000
X41.2 School, other institution and public administrative area	0.003	0.997	0.000
U89 Agent resistant to other and unspecified antibiotics	0.000	0.997	0.003
S62.30 Fracture of other metacarpal bone (closed)	0.003	0.997	0.000
J86.9 Pyothorax without fistula	0.003	0.997	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.003	0.997	0.000
J39.3 Upper respiratory tract hypersensitivity reaction, site unspecified	0.003	0.997	0.000
J39.1 Other abscess of pharynx	0.003	0.997	0.000
J39.0 Retropharyngeal and parapharyngeal abscess	0.003	0.997	0.000
S64.3 Injury of digital nerve of thumb	0.003	0.997	0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle	0.000	0.997	0.003
S60.2 Contusion of other parts of wrist and hand	0.003	0.997	0.000
S62.4 Multiple fractures of metacarpal bones	0.003	0.997	0.000
S65.0 Injury of ulnar artery at wrist and hand level	0.003	0.997	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.000	0.997	0.003
Z09.9 Follow-up examination after unspecified treatment for other conditions	0.003	0.997	0.000
D47.2 Monoclonal gammopathy	0.003	0.997	0.000
E83.3 Disorders of phosphorus metabolism	0.003	0.997	0.000
Q63.2 Ectopic kidney	0.003	0.997	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.003	0.997	0.000
S60.7 Multiple superficial injuries of wrist and hand	0.003	0.997	0.000
S62.40 Multiple fractures of metacarpal bones (closed)	0.003	0.997	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.003	0.997	0.000
Q64.9 Congenital malformation of urinary system, unspecified	0.003	0.997	0.000
Q64.8 Other specified congenital malformations of urinary system	0.003	0.997	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.003	0.997	0.000
Q64.6 Congenital diverticulum of bladder	0.003	0.997	0.000
Q64.5 Congenital absence of bladder and urethra	0.003	0.997	0.000
Q64.4 Malformation of urachus	0.003	0.997	0.000
Q64.2 Congenital posterior urethral valves	0.003	0.997	0.000
Q64.1 Exstrophy of urinary bladder	0.003	0.997	0.000
Q64.0 Epispadias	0.003	0.997	0.000
S65.9 Injury of unspecified blood vessel at wrist and hand level	0.003	0.997	0.000
S65.8 Injury of other blood vessels at wrist and hand level	0.003	0.997	0.000
S65.7 Injury of multiple blood vessels at wrist and hand level	0.003	0.997	0.000
S65.4 Injury of blood vessel(s) of thumb	0.003	0.997	0.000
S65.3 Injury of deep palmar arch	0.003	0.997	0.000
S65.2 Injury of superficial palmar arch	0.003	0.997	0.000
S62.7 Multiple fractures of fingers	0.003	0.997	0.000
S67 Crushing injury of wrist and hand	0.003	0.997	0.000
N18.8 Other chronic renal failure	0.003	0.997	0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.000	0.997	0.003
Q21 Congenital malformations of cardiac septa	0.003	0.997	0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms	0.003	0.997	0.000
J39.9 Disease of upper respiratory tract, unspecified	0.003	0.997	0.000
N99.4 Postprocedural pelvic peritoneal adhesions	0.000	0.997	0.003
S62.1 Fracture of other carpal bone(s)	0.003	0.997	0.000
C76.8 Overlapping lesion of other and ill-defined sites	0.000	0.997	0.003
C76.7 Other ill-defined sites	0.000	0.997	0.003
C76.5 Lower limb	0.000	0.997	0.003
C76.4 Upper limb	0.000	0.997	0.003
C76.3 Pelvis	0.000	0.997	0.003
C78.7 Secondary malignant neoplasm of liver	0.000	0.997	0.003
C81.9 Hodgkin's disease, unspecified	0.000	0.997	0.003
S60.1 Contusion of finger(s) with damage to nail	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations