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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs763009
log Bayes Factor = 56.3134
Chromosome 6   position 28,915,108  (GRCh37) Explore rs763009 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.001 0.999
E10-E14 Diabetes mellitus
0.000 0.003 0.997
E16.2 Hypoglycaemia, unspecified
0.000 0.003 0.997
E10.3 With ophthalmic complications
0.000 0.003 0.997
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.004 0.996
E16 Other disorders of pancreatic internal secretion
0.000 0.004 0.996
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.004 0.996
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.004 0.996
E00-E07 Disorders of thyroid gland
0.000 0.007 0.993
E10.2 With renal complications
0.000 0.050 0.950
E10.1 With ketoacidosis
0.000 0.056 0.944
E10.4 With neurological complications
0.000 0.073 0.927
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.093 0.907
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.844 0.156 0.000
E05.8 Other thyrotoxicosis
0.000 0.199 0.801
E16.1 Other hypoglycaemia
0.000 0.211 0.789
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.227 0.773
E10.5 With peripheral circulatory complications
0.000 0.237 0.763
E10.0 With coma
0.000 0.241 0.759
E14 Unspecified diabetes mellitus
0.000 0.244 0.756
E10.7 With multiple complications
0.000 0.256 0.744
E13 Other specified diabetes mellitus
0.000 0.261 0.739
E12 Malnutrition-related diabetes mellitus
0.000 0.285 0.715
E05.5 Thyroid crisis or storm
0.000 0.285 0.714
E05.4 Thyrotoxicosis factitia
0.000 0.285 0.714
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.285 0.714
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.286 0.714
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.286 0.714
E16.4 Abnormal secretion of gastrin
0.000 0.286 0.714
E16.3 Increased secretion of glucagon
0.000 0.286 0.714
E15 Nondiabetic hypoglycaemic coma
0.000 0.286 0.714
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.288 0.712
E00 Congenital iodine-deficiency syndrome
0.000 0.288 0.712
E10.6 With other specified complications
0.000 0.319 0.681
E40-E46 Malnutrition
0.000 0.335 0.665
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.338 0.662
E07 Other disorders of thyroid
0.000 0.359 0.641
E14.3 With ophthalmic complications
0.000 0.364 0.636
E14.1 With ketoacidosis
0.000 0.396 0.604
E14.4 With neurological complications
0.000 0.406 0.594
E14.6 With other specified complications
0.000 0.411 0.589
E06 Thyroiditis
0.000 0.425 0.575
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.437 0.562
E13.9 Without complications
0.000 0.446 0.554
E14.7 With multiple complications
0.000 0.457 0.542
E14.8 With unspecified complications
0.000 0.459 0.541
E11 Non-insulin-dependent diabetes mellitus
0.000 0.467 0.533
E13.8 With unspecified complications
0.000 0.470 0.530
E13.7 With multiple complications
0.000 0.470 0.530
E13.6 With other specified complications
0.000 0.470 0.530
E13.5 With peripheral circulatory complications
0.000 0.470 0.530
E13.4 With neurological complications
0.000 0.470 0.530
E13.2 With renal complications
0.000 0.470 0.530
E13.1 With ketoacidosis
0.000 0.470 0.530
E13.0 With coma
0.000 0.470 0.530
E13.3 With ophthalmic complications
0.000 0.471 0.529
E14.5 With peripheral circulatory complications
0.000 0.472 0.528
E07.8 Other specified disorders of thyroid
0.000 0.476 0.524
E12.9 Without complications
0.000 0.487 0.513
E12.8 With unspecified complications
0.000 0.487 0.513
E12.7 With multiple complications
0.000 0.487 0.513
E12.6 With other specified complications
0.000 0.487 0.513
E12.5 With peripheral circulatory complications
0.000 0.487 0.513
E12.4 With neurological complications
0.000 0.487 0.513
E12.3 With ophthalmic complications
0.000 0.487 0.513
E12.2 With renal complications
0.000 0.487 0.513
E12.1 With ketoacidosis
0.000 0.487 0.513
E12.0 With coma
0.000 0.487 0.513
E14.2 Withrenal complications
0.000 0.489 0.511
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.489 0.510
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.489 0.510
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.489 0.510
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.489 0.510
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.489 0.510
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.489 0.510
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.489 0.510
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.489 0.510
E14.0 With coma
0.000 0.495 0.505
E11.6 With other specified complications
0.000 0.499 0.501
E10.8 With unspecified complications
0.000 0.511 0.489
K90 Intestinal malabsorption
0.000 0.512 0.488
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.523 0.477
E45 Retarded development following protein-energy malnutrition
0.000 0.523 0.477
E43 Unspecified severe protein-energy malnutrition
0.000 0.523 0.477
E42 Marasmic kwashiorkor
0.000 0.523 0.477
E41 Nutritional marasmus
0.000 0.523 0.477
E40 Kwashiorkor
0.000 0.523 0.477
E06.9 Thyroiditis, unspecified
0.000 0.534 0.466
E11.1 With ketoacidosis
0.000 0.539 0.461
E07.1 Dyshormogenetic goitre
0.000 0.540 0.460
E07.0 Hypersecretion of calcitonin
0.000 0.540 0.460
E11.0 With coma
0.000 0.560 0.440
E03 Other hypothyroidism
0.000 0.565 0.435
E06.1 Subacute thyroiditis
0.000 0.570 0.430
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.571 0.429
E46 Unspecified protein-energy malnutrition
0.000 0.572 0.428
E06.4 Drug-induced thyroiditis
0.000 0.587 0.412
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.587 0.412
E06.0 Acute thyroiditis
0.000 0.587 0.412
E11.2 With renal complications
0.000 0.592 0.408
E06.5 Other chronic thyroiditis
0.000 0.608 0.392
E11.7 With multiple complications
0.000 0.617 0.383
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.001 0.627 0.372
K90.3 Pancreatic steatorrhoea
0.000 0.650 0.350
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.650 0.350
K90.1 Tropical sprue
0.000 0.650 0.350
E44.1 Mild protein-energy malnutrition
0.000 0.658 0.342
E44.0 Moderate protein-energy malnutrition
0.000 0.658 0.342
E11.8 With unspecified complications
0.000 0.668 0.332
E65-E68 Obesity and other hyperalimentation
0.000 0.670 0.330
K90.8 Other intestinal malabsorption
0.000 0.672 0.328
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.676 0.323
E03.5 Myxoedema coma
0.000 0.688 0.312
E03.4 Atrophy of thyroid (acquired)
0.000 0.688 0.312
E03.3 Postinfectious hypothyroidism
0.000 0.688 0.312
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.696 0.304
E03.1 Congenital hypothyroidism without goitre
0.000 0.703 0.297
E50-E64 Other nutritional deficiencies
0.000 0.704 0.296
K90.9 Intestinal malabsorption, unspecified
0.000 0.734 0.266
E03.8 Other specified hypothyroidism
0.000 0.738 0.262
E14.9 Without complications
0.000 0.742 0.258
E11.5 With peripheral circulatory complications
0.000 0.745 0.255
E07.9 Disorder of thyroid, unspecified
0.000 0.748 0.252
E11.3 With ophthalmic complications
0.000 0.762 0.238
E67 Other hyperalimentation
0.000 0.763 0.237
E68 Sequelae of hyperalimentation
0.000 0.763 0.237
E20-E35 Disorders of other endocrine glands
0.000 0.768 0.232
E51 Thiamine deficiency
0.000 0.785 0.215
E24 Cushing's syndrome
0.000 0.785 0.215
E54 Ascorbic acid deficiency
0.000 0.786 0.214
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.788 0.212
E63 Other nutritional deficiencies
0.000 0.788 0.212
E50 Vitamin A deficiency
0.000 0.788 0.212
E60 Dietary zinc deficiency
0.000 0.788 0.212
E59 Dietary selenium deficiency
0.000 0.788 0.212
E52 Niacin deficiency [pellagra]
0.000 0.788 0.212
E56 Other vitamin deficiencies
0.000 0.801 0.199
E83 Disorders of mineral metabolism
0.190 0.802 0.008
C19 Malignant neoplasm of rectosigmoid junction
0.000 0.803 0.197
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.807 0.193
E65 Localised adiposity
0.000 0.817 0.183
E21.3 Hyperparathyroidism, unspecified
0.000 0.817 0.183
E24.9 Cushing's syndrome, unspecified
0.000 0.818 0.182
E58 Dietary calcium deficiency
0.000 0.818 0.182
E24.0 Pituitary-dependent Cushing's disease
0.000 0.819 0.181
E20 Hypoparathyroidism
0.000 0.821 0.179
E55 Vitamin D deficiency
0.000 0.821 0.179
E03.9 Hypothyroidism, unspecified
0.000 0.828 0.172
E24.2 Drug-induced Cushing's syndrome
0.000 0.829 0.171
E67.8 Other specified hyperalimentation
0.000 0.830 0.170
E67.3 Hypervitaminosis D
0.000 0.830 0.170
E67.2 Megavitamin-B6 syndrome
0.000 0.830 0.170
E67.1 Hypercarotenaemia
0.000 0.830 0.170
E67.0 Hypervitaminosis A
0.000 0.830 0.170
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.833 0.167
E32 Diseases of thymus
0.000 0.833 0.167
E30 Disorders of puberty, not elsewhere classified
0.000 0.833 0.167
E83.3 Disorders of phosphorus metabolism
0.163 0.835 0.002
E25 Adrenogenital disorders
0.000 0.835 0.165
E31 Polyglandular dysfunction
0.000 0.837 0.163
E61 Deficiency of other nutrient elements
0.000 0.842 0.158
E28 Ovarian dysfunction
0.000 0.842 0.158
E51.2 Wernicke's encephalopathy
0.000 0.842 0.157
E51.9 Thiamine deficiency, unspecified
0.000 0.845 0.154
E51.8 Other manifestations of thiamine deficiency
0.000 0.845 0.154
E51.1 Beriberi
0.000 0.845 0.154
E24.8 Other Cushing's syndrome
0.000 0.846 0.154
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.846 0.154
E24.3 Ectopic ACTH syndrome
0.000 0.846 0.154
E24.1 Nelson's syndrome
0.000 0.846 0.154
E50.9 Vitamin A deficiency, unspecified
0.000 0.848 0.152
E50.8 Other manifestations of vitamin A deficiency
0.000 0.848 0.152
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.848 0.152
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.848 0.152
E50.5 Vitamin A deficiency with night blindness
0.000 0.848 0.152
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.848 0.152
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.848 0.152
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.848 0.152
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.848 0.152
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.848 0.152
E63.9 Nutritional deficiency, unspecified
0.000 0.848 0.152
E63.8 Other specified nutritional deficiencies
0.000 0.848 0.152
E63.1 Imbalance of constituents of food intake
0.000 0.848 0.152
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.848 0.152
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.848 0.152
E64.8 Sequelae of other nutritional deficiencies
0.000 0.848 0.152
E64.3 Sequelae of rickets
0.000 0.848 0.152
E64.2 Sequelae of vitamin C deficiency
0.000 0.848 0.152
E64.1 Sequelae of vitamin A deficiency
0.000 0.848 0.152
E64.0 Sequelae of protein-energy malnutrition
0.000 0.848 0.152
E53 Deficiency of other B group vitamins
0.000 0.852 0.148
I83 Varicose veins of lower extremities
0.145 0.855 0.000
E56.9 Vitamin deficiency, unspecified
0.000 0.857 0.143
E56.8 Deficiency of other vitamins
0.000 0.857 0.143
E56.0 Deficiency of vitamin E
0.000 0.857 0.143
E83.9 Disorder of mineral metabolism, unspecified
0.137 0.858 0.006
E83.8 Other disorders of mineral metabolism
0.136 0.858 0.006
E83.2 Disorders of zinc metabolism
0.136 0.858 0.006
E83.0 Disorders of copper metabolism
0.136 0.858 0.006
E20.9 Hypoparathyroidism, unspecified
0.000 0.859 0.141
E29 Testicular dysfunction
0.000 0.859 0.141
E21.4 Other specified disorders of parathyroid gland
0.000 0.862 0.138
E21.2 Other hyperparathyroidism
0.000 0.862 0.137
E06.3 Autoimmune thyroiditis
0.001 0.865 0.134
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.869 0.131
E56.1 Deficiency of vitamin K
0.000 0.870 0.129
E20.8 Other hypoparathyroidism
0.000 0.871 0.129
E20.1 Pseudohypoparathyroidism
0.000 0.871 0.129
E20.0 Idiopathic hypoparathyroidism
0.000 0.871 0.129
E55.0 Rickets, active
0.000 0.871 0.128
E34 Other endocrine disorders
0.000 0.872 0.128
E30.9 Disorder of puberty, unspecified
0.000 0.880 0.120
E30.8 Other disorders of puberty
0.000 0.880 0.120
E30.1 Precocious puberty
0.000 0.880 0.120
E30.0 Delayed puberty
0.000 0.880 0.120
E32.9 Disease of thymus, unspecified
0.000 0.880 0.120
E32.8 Other diseases of thymus
0.000 0.880 0.120
E32.1 Abscess of thymus
0.000 0.880 0.120
E32.0 Persistent hyperplasia of thymus
0.000 0.880 0.120
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.880 0.120
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.880 0.120
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.880 0.120
E11.4 With neurological complications
0.000 0.881 0.119
E25.9 Adrenogenital disorder, unspecified
0.000 0.882 0.118
E25.8 Other adrenogenital disorders
0.000 0.882 0.118
E31.9 Polyglandular dysfunction, unspecified
0.000 0.883 0.117
E31.8 Other polyglandular dysfunction
0.000 0.883 0.117
E31.1 Polyglandular hyperfunction
0.000 0.883 0.117
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.883 0.117
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.884 0.116
E26 Hyperaldosteronism
0.000 0.885 0.115
E61.9 Deficiency of nutrient element, unspecified
0.000 0.886 0.114
E61.8 Deficiency of other specified nutrient elements
0.000 0.886 0.114
E61.7 Deficiency of multiple nutrient elements
0.000 0.886 0.114
E61.6 Vanadium deficiency
0.000 0.886 0.114
E61.5 Molybdenum deficiency
0.000 0.886 0.114
E61.4 Chromium deficiency
0.000 0.886 0.114
E61.3 Manganese deficiency
0.000 0.886 0.114
E61.0 Copper deficiency
0.000 0.886 0.114
E28.9 Ovarian dysfunction, unspecified
0.000 0.887 0.113
E28.8 Other ovarian dysfunction
0.000 0.887 0.113
E28.1 Androgen excess
0.000 0.887 0.113
E28.0 Oestrogen excess
0.000 0.887 0.113
E31.0 Autoimmune polyglandular failure
0.000 0.887 0.113
E53.9 Vitamin B deficiency, unspecified
0.000 0.889 0.111
E28.2 Polycystic ovarian syndrome
0.000 0.890 0.110
E28.3 Primary ovarian failure
0.000 0.892 0.108
E53.1 Pyridoxine deficiency
0.000 0.894 0.106
E53.0 Riboflavin deficiency
0.000 0.894 0.106
E29.9 Testicular dysfunction, unspecified
0.000 0.898 0.102
E29.8 Other testicular dysfunction
0.000 0.899 0.101
E29.0 Testicular hyperfunction
0.000 0.899 0.101
E21.0 Primary hyperparathyroidism
0.000 0.900 0.100
E61.2 Magnesium deficiency
0.000 0.902 0.098
I83.0 Varicose veins of lower extremities with ulcer
0.096 0.904 0.000
E22 Hyperfunction of pituitary gland
0.000 0.905 0.095
E55.9 Vitamin D deficiency, unspecified
0.000 0.905 0.095
E23 Hypofunction and other disorders of pituitary gland
0.000 0.906 0.094
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.094 0.906 0.000
E34.3 Short stature, not elsewhere classified
0.000 0.907 0.093
E34.5 Androgen resistance syndrome
0.000 0.908 0.092
E34.4 Constitutional tall stature
0.000 0.908 0.092
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.908 0.092
E34.1 Other hypersecretion of intestinal hormones
0.000 0.908 0.092
C20 Malignant neoplasm of rectum
0.000 0.910 0.090
C15-C26 Malignant neoplasms of digestive organs
0.000 0.911 0.089
E83.4 Disorders of magnesium metabolism
0.086 0.911 0.003
E34.8 Other specified endocrine disorders
0.000 0.912 0.087
C15 Malignant neoplasm of oesophagus
0.000 0.913 0.087
E61.1 Iron deficiency
0.000 0.915 0.085
E34.9 Endocrine disorder, unspecified
0.000 0.917 0.083
E26.8 Other hyperaldosteronism
0.000 0.917 0.083
E26.1 Secondary hyperaldosteronism
0.000 0.917 0.083
M45.X9 Ankylosing spondylitis (Site unspecified)
0.082 0.918 0.000
E23.7 Disorder of pituitary gland, unspecified
0.000 0.920 0.080
C15.4 Middle third of oesophagus
0.000 0.923 0.077
E26.9 Hyperaldosteronism, unspecified
0.000 0.924 0.075
C15.5 Lower third of oesophagus
0.000 0.925 0.075
E34.0 Carcinoid syndrome
0.000 0.927 0.073
E29.1 Testicular hypofunction
0.000 0.927 0.073
E11.9 Without complications
0.000 0.930 0.070
E22.8 Other hyperfunction of pituitary gland
0.000 0.931 0.068
C25 Malignant neoplasm of pancreas
0.000 0.931 0.069
C15.9 Oesophagus, unspecified
0.000 0.931 0.069
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.932 0.068
E23.1 Drug-induced hypopituitarism
0.000 0.932 0.068
C15.0 Cervical part of oesophagus
0.000 0.933 0.067
E22.1 Hyperprolactinaemia
0.000 0.935 0.065
C15.3 Upper third of oesophagus
0.000 0.936 0.064
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.936 0.064
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.000 0.936 0.064
C17 Malignant neoplasm of small intestine
0.000 0.937 0.063
C15.1 Thoracic part of oesophagus
0.000 0.937 0.063
C15.8 Overlapping lesion of oesophagus
0.000 0.937 0.062
C15.2 Abdominal part of oesophagus
0.000 0.937 0.062
C17.0 Duodenum
0.000 0.940 0.060
C21 Malignant neoplasm of anus and anal canal
0.000 0.941 0.059
C25.2 Tail of pancreas
0.000 0.943 0.057
C25.3 Pancreatic duct
0.000 0.943 0.056
C24.0 Extrahepatic bile duct
0.000 0.944 0.056
E04 Other non-toxic goitre
0.001 0.945 0.055
E70-E90 Metabolic disorders
0.001 0.945 0.054
C25.1 Body of pancreas
0.000 0.945 0.055
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.946 0.054
C25.8 Overlapping lesion of pancreas
0.000 0.947 0.053
C25.4 Endocrine pancreas
0.000 0.947 0.053
E23.2 Diabetes insipidus
0.000 0.949 0.051
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.951 0.049
E27 Other disorders of adrenal gland
0.000 0.952 0.048
E78.2 Mixed hyperlipidaemia
0.000 0.952 0.048
E22.0 Acromegaly and pituitary gigantism
0.000 0.953 0.047
E26.0 Primary hyperaldosteronism
0.001 0.953 0.046
C21.8 Overlapping lesion of rectum, anus and anal canal
0.000 0.953 0.047
C25.7 Other parts of pancreas
0.000 0.954 0.046
E23.6 Other disorders of pituitary gland
0.000 0.954 0.046
C24.8 Overlapping lesion of biliary tract
0.000 0.954 0.046
C17.8 Overlapping lesion of small intestine
0.000 0.954 0.045
C17.3 Meckel's diverticulum
0.000 0.954 0.045
E88 Other metabolic disorders
0.000 0.956 0.044
I83.1 Varicose veins of lower extremities with inflammation
0.044 0.956 0.000
E78.1 Pure hyperglyceridaemia
0.000 0.957 0.043
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.001 0.957 0.042
C21.2 Cloacogenic zone
0.000 0.957 0.042
C24.9 Biliary tract, unspecified
0.000 0.958 0.042
C25.9 Pancreas, unspecified
0.000 0.958 0.042
E74 Other disorders of carbohydrate metabolism
0.001 0.959 0.040
E85 Amyloidosis
0.001 0.959 0.040
C21.1 Anal canal
0.000 0.960 0.040
C17.1 Jejunum
0.000 0.960 0.040
E73 Lactose intolerance
0.001 0.960 0.039
E04.8 Other specified non-toxic goitre
0.001 0.960 0.039
E77 Disorders of glycoprotein metabolism
0.001 0.960 0.039
E76 Disorders of glycosaminoglycan metabolism
0.001 0.960 0.039
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.001 0.960 0.039
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.001 0.960 0.039
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.000 0.960 0.040
C23 Malignant neoplasm of gallbladder
0.000 0.961 0.039
E78.6 Lipoprotein deficiency
0.000 0.961 0.039
E84 Cystic fibrosis
0.001 0.961 0.038
R31 Unspecified haematuria
0.038 0.962 0.000
E79 Disorders of purine and pyrimidine metabolism
0.001 0.962 0.037
E70 Disorders of aromatic amino-acid metabolism
0.001 0.962 0.037
C26 Malignant neoplasm of other and ill-defined digestive organs
0.000 0.963 0.037
E88.9 Metabolic disorder, unspecified
0.000 0.963 0.037
E78.3 Hyperchylomicronaemia
0.000 0.963 0.037
E72 Other disorders of amino-acid metabolism
0.001 0.964 0.035
E88.2 Lipomatosis, not elsewhere classified
0.000 0.965 0.035
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.965 0.035
E27.5 Adrenomedullary hyperfunction
0.000 0.965 0.034
E27.0 Other adrenocortical overactivity
0.000 0.965 0.034
E85.4 Organ-limited amyloidosis
0.000 0.965 0.034
E27.1 Primary adrenocortical insufficiency
0.000 0.966 0.034
C21.0 Anus, unspecified
0.000 0.966 0.034
M45 Ankylosing spondylitis
0.034 0.966 0.000
E75.5 Other lipid storage disorders
0.001 0.966 0.033
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.966 0.033
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.968 0.032
E74.3 Other disorders of intestinal carbohydrate absorption
0.001 0.968 0.031
E23.0 Hypopituitarism
0.000 0.968 0.032
E27.9 Disorder of adrenal gland, unspecified
0.000 0.968 0.031
E75.2 Other sphingolipidosis
0.001 0.969 0.030
E75.6 Lipid storage disorder, unspecified
0.001 0.969 0.030
E75.4 Neuronal ceroid lipofuscinosis
0.001 0.969 0.030
E75.3 Sphingolipidosis, unspecified
0.001 0.969 0.030
E75.1 Other gangliosidosis
0.001 0.969 0.030
E75.0 GM2 gangliosidosis
0.001 0.969 0.030
E04.0 Non-toxic diffuse goitre
0.001 0.969 0.030
E85.8 Other amyloidosis
0.001 0.969 0.030
E78.5 Hyperlipidaemia, unspecified
0.000 0.970 0.030
K90-K93 Other diseases of the digestive system
0.000 0.970 0.030
E74.9 Disorder of carbohydrate metabolism, unspecified
0.001 0.970 0.029
E74.8 Other specified disorders of carbohydrate metabolism
0.001 0.970 0.029
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.001 0.970 0.029
E74.2 Disorders of galactose metabolism
0.001 0.970 0.029
E74.1 Disorders of fructose metabolism
0.001 0.970 0.029
E88.8 Other specified metabolic disorders
0.000 0.970 0.029
E85.2 Heredofamilial amyloidosis, unspecified
0.001 0.970 0.029
E85.1 Neuropathic heredofamilial amyloidosis
0.001 0.970 0.029
E85.0 Nonneuropathic heredofamilial amyloidosis
0.001 0.970 0.029
E78.4 Other hyperlipidaemia
0.000 0.970 0.029
E53.8 Deficiency of other specified B group vitamins
0.000 0.971 0.029
E85.3 Secondary systemic amyloidosis
0.001 0.971 0.029
C22.9 Liver, unspecified
0.000 0.971 0.029
E73.8 Other lactose intolerance
0.001 0.971 0.028
E73.1 Secondary lactase deficiency
0.001 0.971 0.028
E73.0 Congenital lactase deficiency
0.001 0.971 0.028
E71.3 Disorders of fatty-acid metabolism
0.001 0.971 0.028
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.001 0.971 0.028
E71.1 Other disorders of branched-chain amino-acid metabolism
0.001 0.971 0.028
E71.0 Maple-syrup-urine disease
0.001 0.971 0.028
E73.9 Lactose intolerance, unspecified
0.001 0.971 0.028
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.001 0.971 0.028
E76.8 Other disorders of glucosaminoglycan metabolism
0.001 0.971 0.028
E76.3 Mucopolysaccharidosis, unspecified
0.001 0.971 0.028
E76.2 Other mucopolysaccharidoses
0.001 0.971 0.028
E76.1 Mucopolysaccharidosis, type II
0.001 0.971 0.028
E76.0 Mucopolysaccharidosis, type I
0.001 0.971 0.028
E77.9 Disorder of glycoprotein metabolism, unspecified
0.001 0.971 0.028
E77.8 Other disorders of glycoprotein metabolism
0.001 0.971 0.028
E77.1 Defects in glycoprotein degradation
0.001 0.971 0.028
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.001 0.971 0.028
C22.7 Other specified carcinomas of liver
0.000 0.971 0.028
C22.4 Other sarcomas of liver
0.000 0.971 0.028
C22.3 Angiosarcoma of liver
0.000 0.971 0.028
C22.2 Hepatoblastoma
0.000 0.971 0.028
E74.0 Glycogen storage disease
0.001 0.971 0.028
C17.9 Small intestine, unspecified
0.000 0.971 0.028
C24.1 Ampulla of Vater
0.000 0.971 0.028
E27.2 Addisonian crisis
0.000 0.972 0.028
E84.0 Cystic fibrosis with pulmonary manifestations
0.001 0.972 0.028
C17.2 Ileum
0.000 0.972 0.028
E84.8 Cystic fibrosis with other manifestations
0.001 0.972 0.027
E84.1 Cystic fibrosis with intestinal manifestations
0.001 0.972 0.027
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.001 0.973 0.027
E79.8 Other disorders of purine and pyrimidine metabolism
0.001 0.973 0.027
E79.1 Lesch-Nyhan syndrome
0.001 0.973 0.027
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.973 0.027
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.001 0.973 0.026
E70.8 Other disorders of aromatic amino-acid metabolism
0.001 0.973 0.026
E70.2 Disorders of tyrosine metabolism
0.001 0.973 0.026
E70.1 Other hyperphenylalaninaemias
0.001 0.973 0.026
E70.0 Classical phenylketonuria
0.001 0.973 0.026
C26.8 Overlapping lesion of digestive system
0.000 0.973 0.027
C26.1 Spleen
0.000 0.973 0.027
E78.0 Pure hypercholesterolaemia
0.000 0.973 0.027
M45.X2 Ankylosing spondylitis (Cervical region)
0.027 0.973 0.000
C22.1 Intrahepatic bile duct carcinoma
0.000 0.973 0.027
E84.9 Cystic fibrosis, unspecified
0.001 0.974 0.025
E66 Obesity
0.000 0.974 0.026
E72.9 Disorder of amino-acid metabolism, unspecified
0.001 0.974 0.025
E72.8 Other specified disorders of amino-acid metabolism
0.001 0.974 0.025
E72.5 Disorders of glycine metabolism
0.001 0.974 0.025
E72.4 Disorders of ornithine metabolism
0.001 0.974 0.025
E72.3 Disorders of lysine and hydroxylysine metabolism
0.001 0.974 0.025
E72.2 Disorders of urea cycle metabolism
0.001 0.974 0.025
E88.3 Tumour lysis syndrome
0.001 0.974 0.025
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.001 0.974 0.025
E72.0 Disorders of amino-acid transport
0.001 0.975 0.024
E70.3 Albinism
0.001 0.975 0.024
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.024 0.975 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.024 0.975 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.024 0.975 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.024 0.975 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.024 0.975 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.024 0.975 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.024 0.976 0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.001 0.977 0.022
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.977 0.023
E27.8 Other specified disorders of adrenal gland
0.000 0.978 0.022
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.978 0.021
E78.8 Other disorders of lipoprotein metabolism
0.000 0.979 0.021
Z71.8 Other specified counselling
0.021 0.979 0.000
E85.9 Amyloidosis, unspecified
0.001 0.979 0.020
E80 Disorders of porphyrin and bilirubin metabolism
0.001 0.980 0.019
S02.40 Fracture of malar and maxillary bones (closed)
0.000 0.980 0.020
C25.0 Head of pancreas
0.000 0.981 0.019
I77 Other disorders of arteries and arterioles
0.000 0.981 0.019
I77.6 Arteritis, unspecified
0.000 0.981 0.019
E66.1 Drug-induced obesity
0.000 0.981 0.019
C26.9 Ill-defined sites within the digestive system
0.001 0.981 0.018
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.018 0.982 0.000
I77.8 Other specified disorders of arteries and arterioles
0.000 0.982 0.018
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.982 0.018
I74.5 Embolism and thrombosis of iliac artery
0.000 0.983 0.017
I74 Arterial embolism and thrombosis
0.000 0.983 0.017
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.983 0.017
I73 Other peripheral vascular diseases
0.000 0.983 0.017
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.000 0.983 0.017
I73.9 Peripheral vascular disease, unspecified
0.000 0.983 0.017
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.984 0.016
C26.0 Intestinal tract, part unspecified
0.000 0.984 0.016
H40.2 Primary angle-closure glaucoma
0.016 0.984 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.984 0.015
K93.1 Megacolon in Chagas' disease
0.000 0.984 0.015
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.984 0.015
Z72.0 Tobacco use
0.016 0.984 0.000
E80.2 Other porphyria
0.001 0.984 0.015
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.985 0.015
E80.7 Disorder of bilirubin metabolism, unspecified
0.001 0.985 0.014
E80.5 Crigler-Najjar syndrome
0.001 0.985 0.014
E80.3 Defects of catalase and peroxydase
0.001 0.985 0.014
E80.0 Hereditary erythropoietic porphyria
0.001 0.985 0.014
E66.0 Obesity due to excess calories
0.000 0.985 0.015
I73.0 Raynaud's syndrome
0.000 0.985 0.015
E04.9 Non-toxic goitre, unspecified
0.000 0.985 0.014
I77.3 Arterial fibromuscular dysplasia
0.000 0.985 0.015
I72 Other aneurysm
0.000 0.985 0.015
I77.2 Rupture of artery
0.000 0.986 0.014
S02.4 Fracture of malar and maxillary bones
0.000 0.986 0.014
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.986 0.014
I77.5 Necrosis of artery
0.000 0.986 0.014
I77.4 Coeliac artery compression syndrome
0.000 0.986 0.014
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.986 0.014
I70 Atherosclerosis
0.000 0.987 0.013
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.987 0.013
E83.5 Disorders of calcium metabolism
0.008 0.987 0.005

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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