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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs764284
log Bayes Factor = 41.8527
Chromosome 6   position 27,312,078  (GRCh37) Explore rs764284 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E83 Disorders of mineral metabolism
0.000 0.322 0.678
E10 Insulin-dependent diabetes mellitus
0.000 0.332 0.668
E10-E14 Diabetes mellitus
0.000 0.342 0.658
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.344 0.656
E70-E90 Metabolic disorders
0.000 0.346 0.654
E10.5 With peripheral circulatory complications
0.000 0.347 0.653
E88 Other metabolic disorders
0.000 0.355 0.645
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.359 0.641
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.361 0.639
E16 Other disorders of pancreatic internal secretion
0.000 0.368 0.632
E16.2 Hypoglycaemia, unspecified
0.000 0.373 0.627
E10.4 With neurological complications
0.000 0.406 0.594
E10.8 With unspecified complications
0.000 0.412 0.588
E13 Other specified diabetes mellitus
0.000 0.429 0.571
E10.9 Without complications
0.000 0.441 0.559
E27.1 Primary adrenocortical insufficiency
0.000 0.442 0.558
E27 Other disorders of adrenal gland
0.000 0.454 0.545
E20-E35 Disorders of other endocrine glands
0.000 0.456 0.544
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.456 0.544
E10.6 With other specified complications
0.000 0.464 0.536
E10.2 With renal complications
0.000 0.470 0.530
E13.9 Without complications
0.000 0.475 0.525
E88.3 Tumour lysis syndrome
0.000 0.487 0.513
E10.7 With multiple complications
0.000 0.488 0.512
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.496 0.504
E40-E46 Malnutrition
0.000 0.506 0.494
E84 Cystic fibrosis
0.000 0.510 0.490
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.514 0.486
E83.8 Other disorders of mineral metabolism
0.000 0.514 0.486
E83.2 Disorders of zinc metabolism
0.000 0.514 0.486
E83.0 Disorders of copper metabolism
0.000 0.514 0.486
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.514 0.486
E70 Disorders of aromatic amino-acid metabolism
0.000 0.521 0.479
E10.3 With ophthalmic complications
0.000 0.528 0.472
E80.4 Gilbert's syndrome
0.000 0.528 0.472
E12 Malnutrition-related diabetes mellitus
0.000 0.528 0.472
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.528 0.472
E10.0 With coma
0.000 0.529 0.470
E77 Disorders of glycoprotein metabolism
0.000 0.531 0.469
E76 Disorders of glycosaminoglycan metabolism
0.000 0.531 0.469
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.531 0.469
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.531 0.469
E10.1 With ketoacidosis
0.000 0.532 0.468
E15 Nondiabetic hypoglycaemic coma
0.000 0.540 0.460
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.541 0.459
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.547 0.453
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.547 0.453
E16.4 Abnormal secretion of gastrin
0.000 0.547 0.453
E16.3 Increased secretion of glucagon
0.000 0.547 0.453
E88.9 Metabolic disorder, unspecified
0.000 0.550 0.449
E65-E68 Obesity and other hyperalimentation
0.000 0.553 0.447
E72 Other disorders of amino-acid metabolism
0.000 0.554 0.445
E25 Adrenogenital disorders
0.000 0.563 0.437
E88.2 Lipomatosis, not elsewhere classified
0.000 0.565 0.434
E20 Hypoparathyroidism
0.000 0.568 0.431
E88.8 Other specified metabolic disorders
0.000 0.573 0.427
E73 Lactose intolerance
0.000 0.581 0.419
E14 Unspecified diabetes mellitus
0.000 0.585 0.415
E13.8 With unspecified complications
0.000 0.590 0.409
E13.7 With multiple complications
0.000 0.590 0.409
E13.6 With other specified complications
0.000 0.590 0.409
E13.5 With peripheral circulatory complications
0.000 0.590 0.409
E13.4 With neurological complications
0.000 0.590 0.409
E13.2 With renal complications
0.000 0.590 0.409
E13.1 With ketoacidosis
0.000 0.590 0.409
E13.0 With coma
0.000 0.590 0.409
E79 Disorders of purine and pyrimidine metabolism
0.000 0.601 0.399
E80.6 Other disorders of bilirubin metabolism
0.000 0.602 0.398
E65 Localised adiposity
0.000 0.603 0.397
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.607 0.393
E27.5 Adrenomedullary hyperfunction
0.000 0.609 0.391
E27.0 Other adrenocortical overactivity
0.000 0.609 0.391
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.610 0.390
E32 Diseases of thymus
0.000 0.610 0.390
E31 Polyglandular dysfunction
0.000 0.610 0.390
E30 Disorders of puberty, not elsewhere classified
0.000 0.610 0.390
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.610 0.390
E80.5 Crigler-Najjar syndrome
0.000 0.610 0.390
E80.3 Defects of catalase and peroxydase
0.000 0.610 0.390
E80.1 Porphyria cutanea tarda
0.000 0.610 0.390
E80.0 Hereditary erythropoietic porphyria
0.000 0.610 0.390
E84.9 Cystic fibrosis, unspecified
0.000 0.612 0.388
E24 Cushing's syndrome
0.000 0.612 0.388
E14.3 With ophthalmic complications
0.000 0.615 0.385
E46 Unspecified protein-energy malnutrition
0.000 0.621 0.379
E27.2 Addisonian crisis
0.000 0.627 0.373
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.630 0.370
E26 Hyperaldosteronism
0.000 0.635 0.365
E80.2 Other porphyria
0.000 0.636 0.364
E16.1 Other hypoglycaemia
0.000 0.636 0.363
E29 Testicular dysfunction
0.000 0.639 0.361
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.640 0.360
E00-E07 Disorders of thyroid gland
0.000 0.644 0.356
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.645 0.354
E45 Retarded development following protein-energy malnutrition
0.000 0.645 0.354
E43 Unspecified severe protein-energy malnutrition
0.000 0.645 0.354
E42 Marasmic kwashiorkor
0.000 0.645 0.354
E41 Nutritional marasmus
0.000 0.645 0.354
E40 Kwashiorkor
0.000 0.645 0.354
E70.3 Albinism
0.000 0.647 0.353
E13.3 With ophthalmic complications
0.000 0.649 0.351
E84.8 Cystic fibrosis with other manifestations
0.000 0.649 0.351
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.649 0.351
E20.9 Hypoparathyroidism, unspecified
0.000 0.649 0.351
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.657 0.343
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.657 0.343
E70.2 Disorders of tyrosine metabolism
0.000 0.657 0.343
E70.1 Other hyperphenylalaninaemias
0.000 0.657 0.343
E70.0 Classical phenylketonuria
0.000 0.657 0.343
E12.9 Without complications
0.000 0.662 0.338
E12.8 With unspecified complications
0.000 0.662 0.338
E12.7 With multiple complications
0.000 0.662 0.338
E12.6 With other specified complications
0.000 0.662 0.338
E12.5 With peripheral circulatory complications
0.000 0.662 0.338
E12.4 With neurological complications
0.000 0.662 0.338
E12.3 With ophthalmic complications
0.000 0.662 0.338
E12.2 With renal complications
0.000 0.662 0.338
E12.1 With ketoacidosis
0.000 0.662 0.338
E12.0 With coma
0.000 0.662 0.338
E71.3 Disorders of fatty-acid metabolism
0.000 0.664 0.336
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.664 0.336
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.664 0.336
E71.0 Maple-syrup-urine disease
0.000 0.664 0.336
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.664 0.336
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.664 0.336
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.664 0.336
E76.2 Other mucopolysaccharidoses
0.000 0.664 0.336
E76.1 Mucopolysaccharidosis, type II
0.000 0.664 0.336
E76.0 Mucopolysaccharidosis, type I
0.000 0.664 0.336
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.664 0.336
E77.8 Other disorders of glycoprotein metabolism
0.000 0.664 0.336
E77.1 Defects in glycoprotein degradation
0.000 0.664 0.336
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.664 0.336
E89.4 Postprocedural ovarian failure
0.000 0.664 0.336
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.670 0.330
E75.5 Other lipid storage disorders
0.000 0.670 0.329
E74 Other disorders of carbohydrate metabolism
0.000 0.671 0.329
E75.6 Lipid storage disorder, unspecified
0.000 0.671 0.329
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.671 0.329
E75.3 Sphingolipidosis, unspecified
0.000 0.671 0.329
E75.1 Other gangliosidosis
0.000 0.671 0.329
E75.0 GM2 gangliosidosis
0.000 0.671 0.329
E24.2 Drug-induced Cushing's syndrome
0.000 0.679 0.321
E67 Other hyperalimentation
0.000 0.679 0.321
E68 Sequelae of hyperalimentation
0.000 0.679 0.321
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.680 0.319
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.680 0.319
E72.5 Disorders of glycine metabolism
0.000 0.680 0.319
E72.4 Disorders of ornithine metabolism
0.000 0.680 0.319
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.680 0.319
E72.2 Disorders of urea cycle metabolism
0.000 0.680 0.319
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.680 0.319
E75.2 Other sphingolipidosis
0.000 0.681 0.319
E14.5 With peripheral circulatory complications
0.000 0.685 0.315
E25.9 Adrenogenital disorder, unspecified
0.000 0.687 0.313
E25.8 Other adrenogenital disorders
0.000 0.687 0.313
E34 Other endocrine disorders
0.000 0.689 0.311
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.689 0.311
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.689 0.311
E20.8 Other hypoparathyroidism
0.000 0.690 0.309
E20.1 Pseudohypoparathyroidism
0.000 0.690 0.309
E20.0 Idiopathic hypoparathyroidism
0.000 0.690 0.309
E89.0 Postprocedural hypothyroidism
0.000 0.695 0.305
E73.8 Other lactose intolerance
0.000 0.699 0.301
E73.1 Secondary lactase deficiency
0.000 0.699 0.301
E73.0 Congenital lactase deficiency
0.000 0.699 0.301
E23 Hypofunction and other disorders of pituitary gland
0.000 0.702 0.298
E83.3 Disorders of phosphorus metabolism
0.000 0.702 0.298
E14.7 With multiple complications
0.000 0.702 0.298
E14.0 With coma
0.000 0.702 0.298
E85 Amyloidosis
0.000 0.703 0.297
E72.0 Disorders of amino-acid transport
0.000 0.704 0.296
E14.2 Withrenal complications
0.000 0.705 0.295
E24.8 Other Cushing's syndrome
0.000 0.708 0.292
E14.6 With other specified complications
0.000 0.713 0.287
E83.5 Disorders of calcium metabolism
0.000 0.713 0.287
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.713 0.286
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.713 0.286
E79.1 Lesch-Nyhan syndrome
0.000 0.713 0.286
E14.1 With ketoacidosis
0.000 0.717 0.283
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.718 0.282
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.718 0.282
E89.1 Postprocedural hypoinsulinaemia
0.000 0.718 0.282
E30.9 Disorder of puberty, unspecified
0.000 0.720 0.280
E30.8 Other disorders of puberty
0.000 0.720 0.280
E30.1 Precocious puberty
0.000 0.720 0.280
E30.0 Delayed puberty
0.000 0.720 0.280
E31.9 Polyglandular dysfunction, unspecified
0.000 0.720 0.280
E31.8 Other polyglandular dysfunction
0.000 0.720 0.280
E31.1 Polyglandular hyperfunction
0.000 0.720 0.280
E31.0 Autoimmune polyglandular failure
0.000 0.720 0.280
E32.9 Disease of thymus, unspecified
0.000 0.720 0.280
E32.8 Other diseases of thymus
0.000 0.720 0.280
E32.1 Abscess of thymus
0.000 0.720 0.280
E32.0 Persistent hyperplasia of thymus
0.000 0.720 0.280
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.720 0.280
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.720 0.280
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.720 0.280
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.722 0.278
E24.3 Ectopic ACTH syndrome
0.000 0.722 0.278
E24.1 Nelson's syndrome
0.000 0.722 0.278
E24.0 Pituitary-dependent Cushing's disease
0.000 0.724 0.276
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.727 0.273
E06 Thyroiditis
0.000 0.727 0.273
E14.4 With neurological complications
0.000 0.732 0.268
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.737 0.263
E26.8 Other hyperaldosteronism
0.000 0.738 0.262
E26.1 Secondary hyperaldosteronism
0.000 0.738 0.262
E26.0 Primary hyperaldosteronism
0.000 0.738 0.262
E29.9 Testicular dysfunction, unspecified
0.000 0.741 0.259
E29.8 Other testicular dysfunction
0.000 0.741 0.259
E29.0 Testicular hyperfunction
0.000 0.741 0.259
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.745 0.255
E00 Congenital iodine-deficiency syndrome
0.000 0.745 0.255
E44.1 Mild protein-energy malnutrition
0.000 0.746 0.254
E44.0 Moderate protein-energy malnutrition
0.000 0.746 0.254
E73.9 Lactose intolerance, unspecified
0.000 0.749 0.251
E27.9 Disorder of adrenal gland, unspecified
0.000 0.755 0.244
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.756 0.244
E14.8 With unspecified complications
0.000 0.756 0.244
E05.9 Thyrotoxicosis, unspecified
0.000 0.756 0.244
E26.9 Hyperaldosteronism, unspecified
0.000 0.763 0.237
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.764 0.236
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.764 0.236
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.764 0.236
E74.2 Disorders of galactose metabolism
0.000 0.764 0.236
E74.1 Disorders of fructose metabolism
0.000 0.764 0.236
E34.9 Endocrine disorder, unspecified
0.000 0.765 0.235
E83.4 Disorders of magnesium metabolism
0.000 0.766 0.234
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.767 0.233
E23.2 Diabetes insipidus
0.000 0.768 0.232
E67.8 Other specified hyperalimentation
0.000 0.770 0.230
E67.3 Hypervitaminosis D
0.000 0.770 0.230
E67.2 Megavitamin-B6 syndrome
0.000 0.770 0.230
E67.1 Hypercarotenaemia
0.000 0.770 0.230
E67.0 Hypervitaminosis A
0.000 0.770 0.230
E29.1 Testicular hypofunction
0.000 0.770 0.230
E89.5 Postprocedural testicular hypofunction
0.000 0.770 0.229
E85.8 Other amyloidosis
0.000 0.771 0.228
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.774 0.226
E28 Ovarian dysfunction
0.000 0.774 0.226
E34.5 Androgen resistance syndrome
0.000 0.777 0.223
E34.4 Constitutional tall stature
0.000 0.777 0.223
E34.3 Short stature, not elsewhere classified
0.000 0.777 0.223
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.777 0.223
E34.1 Other hypersecretion of intestinal hormones
0.000 0.777 0.223
E05.5 Thyroid crisis or storm
0.000 0.777 0.223
E05.4 Thyrotoxicosis factitia
0.000 0.777 0.223
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.777 0.223
E03 Other hypothyroidism
0.000 0.777 0.223
E78.6 Lipoprotein deficiency
0.000 0.781 0.219
E78.4 Other hyperlipidaemia
0.000 0.782 0.218
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.001 0.783 0.217
K90 Intestinal malabsorption
0.000 0.784 0.216
E05.8 Other thyrotoxicosis
0.000 0.784 0.216
E23.7 Disorder of pituitary gland, unspecified
0.000 0.785 0.215
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.785 0.215
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.786 0.214
E23.1 Drug-induced hypopituitarism
0.000 0.786 0.214
E06.5 Other chronic thyroiditis
0.000 0.787 0.213
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.787 0.213
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.787 0.213
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.787 0.213
E07 Other disorders of thyroid
0.000 0.789 0.211
E06.3 Autoimmune thyroiditis
0.000 0.794 0.206
E23.6 Other disorders of pituitary gland
0.000 0.794 0.205
E27.8 Other specified disorders of adrenal gland
0.001 0.796 0.203
E06.1 Subacute thyroiditis
0.000 0.796 0.203
E03.8 Other specified hypothyroidism
0.000 0.799 0.201
E06.4 Drug-induced thyroiditis
0.000 0.804 0.196
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.804 0.196
E06.0 Acute thyroiditis
0.000 0.804 0.196
E78.3 Hyperchylomicronaemia
0.000 0.809 0.191
E34.8 Other specified endocrine disorders
0.000 0.811 0.189
E74.0 Glycogen storage disease
0.001 0.812 0.187
E89.2 Postprocedural hypoparathyroidism
0.000 0.815 0.185
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.817 0.183
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.817 0.183
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.817 0.183
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.817 0.183
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.817 0.183
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.817 0.183
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.817 0.183
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.817 0.183
E85.9 Amyloidosis, unspecified
0.000 0.820 0.180
E24.9 Cushing's syndrome, unspecified
0.000 0.820 0.179
E74.3 Other disorders of intestinal carbohydrate absorption
0.001 0.823 0.176
E22 Hyperfunction of pituitary gland
0.000 0.825 0.174
E06.9 Thyroiditis, unspecified
0.000 0.826 0.174
E34.0 Carcinoid syndrome
0.000 0.827 0.172
E85.3 Secondary systemic amyloidosis
0.000 0.828 0.172
E89.3 Postprocedural hypopituitarism
0.000 0.835 0.164
E28.9 Ovarian dysfunction, unspecified
0.000 0.838 0.162
E28.8 Other ovarian dysfunction
0.000 0.838 0.162
E28.1 Androgen excess
0.000 0.838 0.162
E28.0 Oestrogen excess
0.000 0.838 0.162
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.839 0.160
E03.5 Myxoedema coma
0.000 0.840 0.160
E03.4 Atrophy of thyroid (acquired)
0.000 0.840 0.160
E03.3 Postinfectious hypothyroidism
0.000 0.840 0.160
E78.2 Mixed hyperlipidaemia
0.000 0.843 0.157
K90.3 Pancreatic steatorrhoea
0.000 0.845 0.155
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.845 0.155
K90.1 Tropical sprue
0.000 0.845 0.155
E78.1 Pure hyperglyceridaemia
0.000 0.845 0.155
K90.8 Other intestinal malabsorption
0.000 0.847 0.153
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.848 0.152
E07.1 Dyshormogenetic goitre
0.000 0.849 0.151
E07.0 Hypersecretion of calcitonin
0.000 0.849 0.151
E03.1 Congenital hypothyroidism without goitre
0.000 0.850 0.149
E07.9 Disorder of thyroid, unspecified
0.000 0.854 0.146
E85.4 Organ-limited amyloidosis
0.001 0.856 0.144
E78.8 Other disorders of lipoprotein metabolism
0.000 0.859 0.141
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.864 0.136
E11 Non-insulin-dependent diabetes mellitus
0.000 0.866 0.134
E50-E64 Other nutritional deficiencies
0.000 0.870 0.130
E22.8 Other hyperfunction of pituitary gland
0.000 0.874 0.125
E07.8 Other specified disorders of thyroid
0.000 0.884 0.116
E28.2 Polycystic ovarian syndrome
0.000 0.887 0.113
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.887 0.113
E11.1 With ketoacidosis
0.000 0.890 0.110
E04 Other non-toxic goitre
0.000 0.890 0.110
E11.2 With renal complications
0.000 0.894 0.106
E22.1 Hyperprolactinaemia
0.000 0.897 0.103
E11.6 With other specified complications
0.000 0.898 0.102
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.900 0.100
E28.3 Primary ovarian failure
0.001 0.903 0.097
E11.7 With multiple complications
0.000 0.903 0.096
E11.8 With unspecified complications
0.000 0.904 0.096
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.907 0.093
E63 Other nutritional deficiencies
0.000 0.907 0.093
E50 Vitamin A deficiency
0.000 0.907 0.093
E60 Dietary zinc deficiency
0.000 0.907 0.093
E59 Dietary selenium deficiency
0.000 0.907 0.093
E52 Niacin deficiency [pellagra]
0.000 0.907 0.093
K90.9 Intestinal malabsorption, unspecified
0.000 0.908 0.092
E23.0 Hypopituitarism
0.000 0.909 0.091
E58 Dietary calcium deficiency
0.000 0.910 0.089
E56 Other vitamin deficiencies
0.000 0.911 0.089
E04.0 Non-toxic diffuse goitre
0.000 0.911 0.089
E51 Thiamine deficiency
0.000 0.912 0.087
E11.0 With coma
0.000 0.915 0.085
E11.5 With peripheral circulatory complications
0.000 0.919 0.081
E04.8 Other specified non-toxic goitre
0.000 0.921 0.079
E22.0 Acromegaly and pituitary gigantism
0.000 0.922 0.078
E14.9 Without complications
0.000 0.922 0.078
E11.4 With neurological complications
0.000 0.923 0.077
E53 Deficiency of other B group vitamins
0.000 0.923 0.077
E54 Ascorbic acid deficiency
0.000 0.926 0.074
E66 Obesity
0.000 0.927 0.073
E86 Volume depletion
0.000 0.927 0.073
E04.9 Non-toxic goitre, unspecified
0.000 0.927 0.073
E55 Vitamin D deficiency
0.000 0.929 0.071
E50.9 Vitamin A deficiency, unspecified
0.000 0.933 0.067
E50.8 Other manifestations of vitamin A deficiency
0.000 0.933 0.067
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.933 0.067
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.933 0.067
E50.5 Vitamin A deficiency with night blindness
0.000 0.933 0.067
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.933 0.067
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.933 0.067
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.933 0.067
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.933 0.067
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.933 0.067
E63.9 Nutritional deficiency, unspecified
0.000 0.933 0.067
E63.8 Other specified nutritional deficiencies
0.000 0.933 0.067
E63.1 Imbalance of constituents of food intake
0.000 0.933 0.067
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.933 0.067
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.933 0.067
E64.8 Sequelae of other nutritional deficiencies
0.000 0.933 0.067
E64.3 Sequelae of rickets
0.000 0.933 0.067
E64.2 Sequelae of vitamin C deficiency
0.000 0.933 0.067
E64.1 Sequelae of vitamin A deficiency
0.000 0.933 0.067
E64.0 Sequelae of protein-energy malnutrition
0.000 0.933 0.067
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.933 0.066
E56.9 Vitamin deficiency, unspecified
0.000 0.936 0.064
E56.8 Deficiency of other vitamins
0.000 0.936 0.064
E56.0 Deficiency of vitamin E
0.000 0.936 0.064
E51.9 Thiamine deficiency, unspecified
0.000 0.937 0.063
E51.8 Other manifestations of thiamine deficiency
0.000 0.937 0.063
E51.1 Beriberi
0.000 0.937 0.063
E53.9 Vitamin B deficiency, unspecified
0.000 0.939 0.061
E56.1 Deficiency of vitamin K
0.000 0.940 0.059
E51.2 Wernicke's encephalopathy
0.000 0.943 0.057
E53.1 Pyridoxine deficiency
0.000 0.944 0.055
E53.0 Riboflavin deficiency
0.000 0.944 0.055
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.945 0.055
E61 Deficiency of other nutrient elements
0.000 0.947 0.053
E66.1 Drug-induced obesity
0.000 0.948 0.052
E55.0 Rickets, active
0.000 0.949 0.051
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.951 0.049
E21.4 Other specified disorders of parathyroid gland
0.000 0.954 0.046
E21.2 Other hyperparathyroidism
0.000 0.955 0.045
E66.0 Obesity due to excess calories
0.000 0.957 0.043
E04.2 Non-toxic multinodular goitre
0.000 0.959 0.041
E61.9 Deficiency of nutrient element, unspecified
0.000 0.961 0.038
E61.8 Deficiency of other specified nutrient elements
0.000 0.961 0.038
E61.7 Deficiency of multiple nutrient elements
0.000 0.961 0.038
E61.6 Vanadium deficiency
0.000 0.961 0.038
E61.5 Molybdenum deficiency
0.000 0.961 0.038
E61.4 Chromium deficiency
0.000 0.961 0.038
E61.3 Manganese deficiency
0.000 0.961 0.038
E61.0 Copper deficiency
0.000 0.961 0.038
E11.3 With ophthalmic complications
0.000 0.963 0.037
K51.2 Ulcerative (chronic) proctitis
0.034 0.966 0.000
E61.2 Magnesium deficiency
0.001 0.968 0.032
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.001 0.968 0.031
E55.9 Vitamin D deficiency, unspecified
0.000 0.971 0.029
E53.8 Deficiency of other specified B group vitamins
0.000 0.975 0.025
R31 Unspecified haematuria
0.017 0.983 0.000
E21.3 Hyperparathyroidism, unspecified
0.000 0.984 0.016
E61.1 Iron deficiency
0.001 0.985 0.014
E04.1 Non-toxic single thyroid nodule
0.000 0.985 0.014
K90-K93 Other diseases of the digestive system
0.000 0.987 0.013
E78.5 Hyperlipidaemia, unspecified
0.000 0.988 0.012
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.011 0.989 0.000
E03.9 Hypothyroidism, unspecified
0.000 0.989 0.011
E21.0 Primary hyperparathyroidism
0.000 0.990 0.009
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.991 0.009
E66.9 Obesity, unspecified
0.000 0.991 0.009
G35 Multiple sclerosis
0.000 0.991 0.009
H11.9 Disorder of conjunctiva, unspecified
0.009 0.991 0.000
H11 Other disorders of conjunctiva
0.008 0.992 0.000
H11.8 Other specified disorders of conjunctiva
0.008 0.992 0.000
H11.4 Other conjunctival vascular disorders and cysts
0.008 0.992 0.000
M41.9 Scoliosis, unspecified
0.008 0.992 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.008 0.992 0.000
C71.2 Temporal lobe
0.008 0.992 0.000
H11.0 Pterygium
0.007 0.993 0.000
G30.9 Alzheimer's disease, unspecified
0.000 0.993 0.007
E11.9 Without complications
0.000 0.993 0.007
M41.95 Scoliosis, unspecified (Thoracolumbar region)
0.007 0.993 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.993 0.007
K93.1 Megacolon in Chagas' disease
0.000 0.993 0.007
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.993 0.007
O04.9 Complete or unspecified, without complication
0.007 0.993 0.000
M41.97 Scoliosis, unspecified (Lumbosacral region)
0.007 0.993 0.000
N04.9 Unspecified
0.000 0.993 0.007
M41.94 Scoliosis, unspecified (Thoracic region)
0.007 0.993 0.000
H11.1 Conjunctival degenerations and deposits
0.006 0.993 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.994 0.006
M41.99 Scoliosis, unspecified (Site unspecified)
0.006 0.994 0.000
G30 Alzheimer's disease
0.000 0.994 0.006
G31.8 Other specified degenerative diseases of nervous system
0.000 0.994 0.006
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.000 0.994 0.006
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)
0.006 0.994 0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)
0.006 0.994 0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)
0.006 0.994 0.000
H11.2 Conjunctival scars
0.006 0.994 0.000
E66.8 Other obesity
0.000 0.994 0.006
K14.0 Glossitis
0.000 0.994 0.006
C71 Malignant neoplasm of brain
0.006 0.994 0.000
M41.92 Scoliosis, unspecified (Cervical region)
0.005 0.994 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.000 0.994 0.006
G31.0 Circumscribed brain atrophy
0.000 0.995 0.005
G30.0 Alzheimer's disease with early onset
0.000 0.995 0.005
C71.0 Cerebrum, except lobes and ventricles
0.005 0.995 0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)
0.005 0.995 0.000
C71.9 Brain, unspecified
0.005 0.995 0.000
G30-G32 Other degenerative diseases of the nervous system
0.000 0.995 0.005
C71.3 Parietal lobe
0.005 0.995 0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)
0.005 0.995 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.000 0.995 0.005
E87.4 Mixed disorder of acid-base balance
0.000 0.995 0.005
G30.1 Alzheimer's disease with late onset
0.000 0.995 0.005
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.000 0.995 0.005
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)
0.005 0.995 0.000
E87.7 Fluid overload
0.000 0.995 0.005
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
0.000 0.995 0.005
D47.1 Chronic myeloproliferative disease
0.000 0.996 0.004
G31.1 Senile degeneration of brain, not elsewhere classified
0.000 0.996 0.004
M41 Scoliosis
0.004 0.996 0.000
G30.8 Other Alzheimer's disease
0.000 0.996 0.004
C71.7 Brain stem
0.004 0.996 0.000
C71.6 Cerebellum
0.004 0.996 0.000
D47.4 Osteomyelofibrosis
0.000 0.996 0.004
E87.0 Hyperosmolality and hypernatraemia
0.000 0.996 0.004
Y85.0 Sequelae of motor-vehicle accident
0.004 0.996 0.000
C71.5 Cerebral ventricle
0.004 0.996 0.000
M25.57 Pain in joint (Ankle and foot)
0.000 0.996 0.004
D73.8 Other diseases of spleen
0.000 0.996 0.004
K07.3 Anomalies of tooth position
0.004 0.996 0.000
C71.8 Overlapping lesion of brain
0.004 0.996 0.000
I49.5 Sick sinus syndrome
0.004 0.996 0.000
N04 Nephrotic syndrome
0.000 0.996 0.004
C71.4 Occipital lobe
0.004 0.996 0.000
K51.4 Pseudopolyposis of colon
0.004 0.996 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.996 0.004
D73 Diseases of spleen
0.000 0.996 0.004
K51 Ulcerative colitis
0.004 0.996 0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]
0.000 0.996 0.004
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour
0.000 0.996 0.004
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.996 0.003
E87.5 Hyperkalaemia
0.000 0.996 0.004
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.000 0.996 0.003
D73.5 Infarction of spleen
0.000 0.996 0.003
M41.4 Neuromuscular scoliosis
0.003 0.997 0.000
M41.3 Thoracogenic scoliosis
0.003 0.997 0.000
M41.2 Other idiopathic scoliosis
0.003 0.997 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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